Alignment of TRAD_HUMAN_whole with 1bf6A0

Alignment of TRAD_HUMAN_whole with 1bf6A0

PSSM Score Key
-10																			10

Bad																			Good

TRAD_H_PSS	Predicted Secondary Structure for your Sequence
TRAD_H_Seq	Your Sequence
1bf6A0_Seq	Library Sequence
1bf6A0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

TRAD_H_PSS

C

C

C

C

C

C

C

H

H

H

H

E

E

E

E

E

E

E

E

E

C

H

H

H

H

H

H

H

H

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

.

.

.

TRAD_H_Seq

M

A

A

G

Q

N

G

H

E

E

W

V

G

S

A

Y

L

F

V

E

S

S

L

D

K

V

V

L

S

D

A

Y

A

H

P

Q

Q

K

V

A

V

Y

R

A

L

Q

A

.

.

.

-------

+

-

-

G

-

-

-

-

+

L

+

+

+

S

-

-

K

-

-

-

+

+

-

-

-

-

+

-

-

-

-

L

+

1bf6A0_Seq

.

S

F

D

P

T

G

Y

.

.

T

L

A

H

E

H

L

H

I

D

L

S

G

F

K

N

N

V

D

C

R

L

D

Q

Y

A

F

I

C

Q

E

M

N

D

L

M

T

R

G

V

1bf6A0_SS

.

C

C

C

C

C

C

E

.

.

E

E

E

E

E

C

C

C

E

E

H

H

H

H

H

C

C

H

H

H

E

E

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

E

CORE

.

0

1

0

0

0

0

0

.

.

1

4

2

0

0

0

5

0

0

0

0

0

0

0

0

0

0

0

0

0

0

2

0

0

0

0

0

3

1

0

0

3

0

0

4

0

0

0

0

3

TRAD_H_PSS

.

H

H

H

C

C

C

C

.

.

.

C

C

C

H

H

H

H

H

H

H

H

C

C

.

C

C

E

E

E

E

E

E

H

H

.

.

H

C

C

C

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

.

A

L

A

E

S

G

G

.

.

.

S

P

D

V

L

Q

M

L

K

I

H

R

S

.

D

P

Q

L

I

V

Q

L

R

F

.

.

C

G

R

Q

P

C

G

R

F

L

R

A

Y

-------

+

+

E

-

-

-

+

-

+

+

-

-

M

L

+

-

R

+

-

+

+

+

-

-

-

+

-

-

-

P

-

+

-

-

+

R

-

1bf6A0_Seq

R

N

V

I

E

M

T

N

R

Y

M

G

R

N

A

Q

F

M

L

D

V

M

R

E

T

G

I

N

V

V

A

C

T

G

Y

Y

Q

D

A

F

F

P

E

H

V

A

T

R

S

V

1bf6A0_SS

E

E

E

E

E

C

C

C

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

E

E

E

C

E

E

C

C

C

C

H

H

H

C

C

H

H

H

H

H

C

C

H

CORE

0

0

6

2

0

1

0

0

0

0

0

0

0

0

1

0

1

2

0

0

5

1

0

0

0

0

4

0

4

1

2

1

2

3

0

0

0

0

0

0

0

0

0

0

1

0

0

0

0

0

TRAD_H_PSS

H

H

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

E

E

E

E

E

C

C

C

H

H

H

H

H

H

H

C

C

C

C

H

H

H

H

H

H

H

H

TRAD_H_Seq

R

E

G

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

H

S

V

P

L

Q

L

E

L

R

A

G

A

E

R

L

D

A

L

L

A

D

E

E

R

C

L

S

C

I

L

-------

E

-

-

L

+

A

G

-

+

+

I

-

1bf6A0_Seq

Q

E

.

.

.

.

L

A

Q

E

M

V

D

E

I

E

Q

G

I

D

G

T

E

L

.

.

.

.

K

A

G

.

.

.

.

.

.

.

.

.

.

.

.

.

I

I

A

E

I

G

1bf6A0_SS

H

H

.

.

.

.

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

.

.

.

.

C

C

C

.

.

.

.

.

.

.

.

.

.

.

.

.

E

E

E

E

E

E

CORE

0

0

.

.

.

.

1

2

0

0

4

1

0

0

2

0

0

0

2

0

0

0

0

2

.

.

.

.

0

2

0

.

.

.

.

.

.

.

.

.

.

.

.

.

2

6

1

0

7

0

TRAD_H_PSS

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

E

E

C

C

C

C

.

.

.

.

.

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

TRAD_H_Seq

A

Q

Q

P

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

N

L

K

C

G

S

G

.

.

.

.

.

A

R

G

G

D

G

E

V

A

S

A

P

L

Q

X

X

X

X

-------

+

+

+

-

G

-

-

+

+

+

-

+

G

+

-

-

A

-

L

Q

1bf6A0_Seq

T

S

E

G

K

I

T

P

L

E

E

K

V

F

I

A

A

A

L

A

H

N

Q

T

G

R

P

I

S

T

H

T

S

F

S

T

M

G

L

E

Q

L

A

L

L

Q

A

H

G

V

1bf6A0_SS

C

E

C

C

E

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

E

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

CORE

0

0

0

0

0

0

0

0

0

0

0

0

3

3

0

2

9

4

0

3

0

0

0

1

0

0

0

8

1

5

0

1

0

0

0

0

0

2

1

0

0

6

0

0

9

0

0

0

0

6

TRAD_H_PSS

H

H

H

H

H

H

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

H

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

TRAD_H_Seq

X

X

X

X

X

X

.

.

.

.

.

.

.

.

.

X

X

X

X

X

X

X

A

Q

T

F

L

F

Q

G

Q

P

V

V

N

R

P

L

S

L

K

D

Q

Q

T

F

A

R

S

V

-------

+

+

-

-

-

+

-

+

-

-

-

+

-

+

-

+

-

D

+

-

+

1bf6A0_Seq

D

L

S

R

V

T

V

G

H

C

D

L

K

D

N

L

D

N

I

L

K

M

I

D

L

G

A

Y

V

Q

F

D

T

I

G

K

N

S

Y

Y

P

D

E

.

.

.

.

K

R

I

1bf6A0_SS

C

H

H

H

E

E

E

E

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

C

C

E

E

E

E

C

C

C

C

C

C

C

C

C

C

H

H

.

.

.

.

H

H

H

CORE

0

4

0

0

8

1

7

1

0

2

0

0

0

0

0

1

0

0

4

1

0

5

4

0

2

0

8

0

7

0

3

0

0

2

0

0

0

0

0

0

0

0

0

.

.

.

.

0

0

0

TRAD_H_PSS

C

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

TRAD_H_Seq

G

L

K

W

R

K

V

G

R

S

L

Q

R

G

C

R

A

L

R

D

P

A

L

D

S

L

A

Y

E

Y

E

R

E

G

L

Y

E

Q

A

F

Q

L

L

R

R

F

V

Q

A

E

-------

+

+

-

-

+

-

+

-

R

L

-

-

-

-

-

D

+

-

-

-

S

-

-

+

-

-

-

G

Y

-

-

-

-

-

-

-

+

-

1bf6A0_Seq

A

M

L

H

A

L

R

D

R

G

L

L

N

R

V

M

L

S

M

D

I

T

R

R

S

H

L

K

A

N

G

G

Y

G

.

Y

D

Y

L

L

T

T

F

I

P

Q

L

R

Q

S

1bf6A0_SS

H

H

H

H

H

H

H

H

H

C

C

H

H

H

E

E

E

C

C

C

C

C

C

H

H

H

C

H

H

H

C

C

C

C

.

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

CORE

0

1

4

0

0

6

0

0

0

0

2

2

0

0

6

1

4

1

1

0

1

0

0

0

0

0

2

0

0

0

0

0

0

0

.

1

0

0

3

2

0

0

1

2

0

0

2

0

0

0

TRAD_H_PSS

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

TRAD_H_Seq

G

R

R

A

T

L

Q

R

L

V

E

A

L

E

E

N

E

L

T

S

L

A

E

D

L

L

G

L

T

D

P

N

G

G

L

A

-------

G

-

+

-

-

+

-

-

-

L

-

E

N

-

-

-

1bf6A0_Seq

G

.

.

F

S

Q

A

D

V

D

V

M

L

R

E

N

.

.

.

.

.

P

S

Q

F

F

.

.

.

.

.

.

.

.

.

Q

1bf6A0_SS

C

.

.

C

C

H

H

H

H

H

H

H

H

H

H

H

.

.

.

.

.

H

H

H

H

H

.

.

.

.

.

.

.

.

.

C

CORE

0

.

.

2

0

0

0

0

1

0

0

3

2

0

0

0

.

.

.

.

.

0

0

0

1

2

.

.

.

.

.

.

.

.

.

0