Alignment of TRAD_HUMAN_whole with 1bcw-0

Alignment of TRAD_HUMAN_whole with 1bcw-0

PSSM Score Key
-10																			10

Bad																			Good

TRAD_H_PSS	Predicted Secondary Structure for your Sequence
TRAD_H_Seq	Your Sequence
1bcw-0_Seq	Library Sequence
1bcw-0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

TRAD_H_PSS		C	C	C	C	C	C	C	H	H	H		H	E	E	E	E	E	E	E	E	E		C	H	H	H	H	H	H	H	H	C		C	C	C	C	C	H	H	H	H	H		H	H	H	H	H	H	H	H	H	H
TRAD_H_Seq		M	A	A	G	Q	N	G	H	E	E		W	V	G	S	A	Y	L	F	V	E		S	S	L	D	K	V	V	L	S	D		A	Y	A	H	P	Q	Q	K	V	A		V	Y	R	A	L	Q	A	A	L	A
-------		-	-	-	G	-	-																										-		+	+		+		-	-	-		-		+		-	+	L			A
1bcw-0_Seq		A	L	R	G	T	V	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	T		D	F	S	G	F	D	G	R	A	D		A	.	E	V	L	R	K	A	.	.
1bcw-0_SS		C	C	C	C	C	C	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	C		C	C	C	C	C	C	H	H	H	H		H	.	H	H	H	H	H	H	.	.
CORE		0	0	0	0	0	2	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	0		0	0	0	0	1	0	1	0	0	0		4	.	0	0	6	0	0	2	.	.

TRAD_H_PSS

C

C

C

C

C

C

C

H

H

H

H

H

H

H

.

.

H

C

C

C

C

E

E

E

E

E

E

H

H

H

C

C

C

H

.

H

H

H

H

H

H

H

H

H

H

C

C

C

C

H

TRAD_H_Seq

E

S

G

G

S

P

D

V

L

Q

M

L

K

I

.

.

H

R

S

D

P

Q

L

I

V

Q

L

R

F

C

G

R

Q

P

.

C

G

R

F

L

R

A

Y

R

E

G

X

X

X

X

-------

-

G

-

-

-

D

-

-

-

L

+

+

R

S

-

-

Q

R

Q

-

+

-

-

F

+

+

+

+

-

1bcw-0_Seq

M

K

G

L

G

T

D

E

D

S

I

L

N

L

L

T

A

R

S

N

A

Q

.

.

.

.

.

.

.

.

.

R

Q

Q

I

A

E

E

F

K

T

L

F

G

R

D

L

V

N

D

1bcw-0_SS

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

CORE

3

0

0

0

0

2

0

0

0

0

5

2

0

2

4

3

0

0

0

0

0

0

.

.

.

.

.

.

.

.

.

0

0

0

4

3

0

0

3

0

0

1

0

0

0

0

6

1

0

0

TRAD_H_PSS

H

H

H

H

.

.

.

.

H

H

H

H

H

H

C

C

C

C

C

C

E

E

E

E

E

C

C

C

H

H

H

H

.

H

H

H

.

.

C

C

C

C

H

H

H

H

H

H

H

H

TRAD_H_Seq

X

X

X

X

.

.

.

.

X

X

X

X

X

X

X

X

H

S

V

P

L

Q

L

E

L

R

A

G

A

E

R

L

.

D

A

L

.

.

L

A

D

E

E

R

C

L

S

C

I

L

-------

-

-

-

+

+

-

+

A

-

L

+

A

L

+

-

-

+

E

+

L

-

-

I

+

1bcw-0_Seq

M

K

S

E

L

A

G

K

F

E

K

L

I

V

A

L

M

K

P

S

R

L

Y

D

.

.

.

.

A

Y

E

L

K

H

A

L

K

G

A

G

T

D

E

K

V

L

T

E

I

I

1bcw-0_SS

H

H

H

H

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

.

.

.

.

H

H

H

H

H

H

H

H

C

C

C

C

C

C

H

H

H

H

H

H

H

H

CORE

4

0

0

0

1

0

0

0

2

0

0

7

3

0

3

3

4

0

0

0

0

0

1

0

.

.

.

.

2

0

0

7

0

0

4

6

0

0

0

0

2

0

0

0

3

9

2

0

1

6

TRAD_H_PSS

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

.

H

TRAD_H_Seq

A

Q

Q

P

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

N

L

K

C

G

S

G

A

R

G

G

D

G

E

V

A

S

A

P

L

Q

X

X

X

X

X

X

X

.

X

-------

A

-

-

-

+

G

-

+

L

1bcw-0_Seq

A

.

.

.

.

.

S

R

T

P

E

E

L

R

A

I

K

Q

A

Y

E

E

E

Y

G

.

.

.

.

.

.

.

.

.

.

.

.

S

N

L

E

D

D

V

V

G

D

T

S

G

1bcw-0_SS

H

.

.

.

.

.

H

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

.

.

.

.

.

.

.

.

.

.

.

.

C

C

H

H

H

H

H

H

H

H

C

C

H

CORE

7

.

.

.

.

.

1

0

0

0

0

0

3

0

0

4

0

0

1

2

0

0

0

0

0

.

.

.

.

.

.

.

.

.

.

.

.

0

0

6

0

0

0

7

0

0

0

3

0

0

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

H

H

H

.

.

.

.

H

H

H

H

H

TRAD_H_Seq

X

X

X

X

X

X

X

X

X

A

Q

T

F

L

F

Q

G

Q

P

V

V

N

R

P

L

S

L

K

D

Q

Q

T

F

A

R

S

V

G

L

K

W

.

.

.

.

R

K

V

G

R

-------

+

Q

+

-

-

+

+

+

-

-

+

-

-

+

D

-

Q

-

-

-

L

K

W

-

K

+

-

+

1bcw-0_Seq

Y

Y

Q

R

M

L

V

V

L

L

Q

A

N

R

D

P

D

.

T

A

I

D

D

A

Q

V

E

L

D

A

Q

A

L

F

Q

A

G

E

L

K

W

G

T

D

E

E

K

F

I

T

1bcw-0_SS

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

.

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

H

H

H

H

H

H

CORE

0

1

0

0

7

7

0

1

5

5

0

1

0

0

0

0

0

.

0

0

0

0

0

0

0

1

0

0

0

1

0

0

6

0

0

2

2

0

0

0

0

0

1

0

0

0

0

5

3

0

TRAD_H_PSS

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

C

.

.

.

.

.

.

.

.

.

.

.

.

.

.

C

C

C

C

H

H

H

H

H

.

.

.

.

.

.

TRAD_H_Seq

S

L

Q

R

G

C

R

A

L

R

D

P

A

L

D

S

L

A

Y

E

Y

.

.

.

.

.

.

.

.

.

.

.

.

.

.

E

R

E

G

L

Y

E

Q

A

.

.

.

.

.

.

-------

-

L

-

-

-

+

-

L

-

-

-

+

+

Y

E

-

G

-

+

E

+

1bcw-0_Seq

I

L

.

.

.

.

G

T

R

S

V

S

H

L

R

R

V

F

D

K

Y

M

T

I

S

G

F

Q

I

E

E

T

I

D

R

E

T

S

G

N

L

E

N

L

L

L

A

V

V

K

1bcw-0_SS

H

H

.

.

.

.

H

H

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

H

H

H

H

H

H

H

CORE

2

9

.

.

.

.

3

0

0

0

0

0

0

3

0

0

2

4

0

0

1

0

0

0

0

0

0

0

5

0

0

1

4

0

0

0

1

0

0

0

3

0

0

7

6

1

3

7

6

0

TRAD_H_PSS

.

.

.

.

.

.

.

.

H

.

H

H

H

H

H

H

H

H

H

C

C

C

C

.

.

.

.

.

.

C

H

H

H

H

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

.

.

.

.

.

.

.

.

F

.

Q

L

L

R

R

F

V

Q

A

E

G

R

R

.

.

.

.

.

.

A

T

L

Q

R

.

.

.

.

.

.

.

L

V

E

A

L

E

E

N

E

-------

+

L

+

-

+

-

-

G

-

+

-

-

R

-

+

-

+

N

-

1bcw-0_Seq

S

I

R

S

I

P

A

Y

L

A

E

T

L

Y

Y

A

M

K

G

A

G

T

D

D

H

T

L

I

R

V

I

V

S

R

S

E

I

D

L

F

N

I

R

K

E

F

R

K

N

F

1bcw-0_SS

H

H

H

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

CORE

2

1

0

0

0

1

0

0

2

3

0

0

8

0

0

0

5

0

0

0

0

2

0

0

0

0

7

3

0

3

5

5

0

0

0

0

0

0

3

0

0

5

0

0

0

5

0

0

0

0

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

C

C

C

.

.

.

.

.

.

.

.

.

.

C

C

C

C

C

C

C

TRAD_H_Seq

L

T

S

L

A

E

D

L

L

G

L

T

.

.

.

.

.

.

.

.

.

.

D

P

N

G

G

L

A

-------

-

T

S

L

+

G

-

T

-

-

-

G

-

-

1bcw-0_Seq

A

T

S

L

Y

S

M

I

K

G

D

T

S

G

D

Y

K

K

A

L

L

L

L

C

G

G

E

D

D

1bcw-0_SS

C

C

C

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

CORE

0

1

0

6

0

0

2

4

0

0

0

2

0

0

0

1

0

0

5

6

1

1

6

1

0

0

0

0

0