Alignment of TRAD_HUMAN_whole with 1ad5B3

Alignment of TRAD_HUMAN_whole with 1ad5B3

PSSM Score Key
-10																			10

Bad																			Good

TRAD_H_PSS	Predicted Secondary Structure for your Sequence
TRAD_H_Seq	Your Sequence
1ad5B3_Seq	Library Sequence
1ad5B3_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

TRAD_H_PSS

C

C

C

C

C

C

C

H

H

H

H

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

E

E

E

E

E

E

E

E

E

C

H

H

H

H

H

H

H

H

C

C

C

C

TRAD_H_Seq

M

A

A

G

Q

N

G

H

E

E

W

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

V

G

S

A

Y

L

F

V

E

S

S

L

D

K

V

V

L

S

D

A

Y

A

-------

-

-

-

+

-

-

+

W

-

G

-

+

+

-

+

-

-

-

K

V

-

+

-

-

-

-

1ad5B3_Seq

K

P

Q

K

P

W

E

K

D

A

W

E

I

P

R

E

S

L

K

L

E

K

K

L

G

A

G

Q

F

G

E

V

W

M

A

T

Y

N

K

H

T

K

V

A

V

K

T

M

K

P

1ad5B3_SS

C

C

C

C

C

C

C

C

C

C

C

E

E

C

H

H

H

E

E

E

E

E

E

E

E

C

C

C

C

E

E

E

E

E

E

E

E

C

C

C

E

E

E

E

E

E

E

E

C

C

CORE

0

0

0

0

0

0

0

0

0

0

0

0

3

0

0

0

0

4

0

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

4

0

0

0

0

0

0

0

3

0

3

0

0

0

0

0

TRAD_H_PSS

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

E

E

H

H

H

C

C

C

H

H

TRAD_H_Seq

H

P

Q

Q

K

V

A

V

Y

R

A

L

Q

A

A

L

A

E

S

G

G

S

P

D

V

L

Q

M

L

K

I

H

R

S

D

P

Q

L

I

V

Q

L

R

F

C

G

R

Q

P

C

-------

+

-

-

A

+

+

A

+

-

-

+

+

+

+

+

+

-

+

+

P

-

-

I

+

+

-

F

+

+

-

-

1ad5B3_Seq

G

S

M

S

V

E

A

F

L

A

.

.

E

A

N

V

M

K

T

L

Q

H

D

K

L

V

K

L

H

A

V

V

T

K

E

P

I

Y

I

I

.

T

E

F

M

A

K

G

S

L

1ad5B3_SS

C

C

C

C

H

H

H

H

H

H

.

.

H

H

H

H

H

H

C

C

C

C

C

C

E

C

C

E

E

E

E

E

C

C

C

C

E

E

E

E

.

E

E

C

C

C

C

E

E

H

CORE

0

0

0

0

0

0

0

0

0

0

.

.

0

0

0

0

0

0

0

1

0

0

0

0

3

1

0

0

0

2

1

2

0

0

0

0

0

0

1

4

.

0

0

0

0

0

0

0

0

8

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

E

E

E

E

E

C

C

C

H

H

H

H

H

H

H

C

C

C

C

H

TRAD_H_Seq

G

R

F

L

R

A

Y

R

E

G

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

H

S

V

P

L

Q

L

E

L

R

A

G

A

E

R

L

D

A

L

L

A

D

E

E

-------

-

F

L

+

-

+

+

G

-

+

-

+

-

1ad5B3_Seq

L

D

F

L

K

S

D

E

G

S

K

Q

P

L

P

K

L

I

D

F

S

A

Q

I

A

E

.

.

.

.

.

.

.

.

.

.

.

G

M

A

F

I

E

Q

R

.

.

.

.

.

1ad5B3_SS

H

H

H

H

H

C

H

H

H

H

H

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

.

.

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

.

.

.

.

.

CORE

1

0

1

2

0

0

0

0

0

0

0

0

0

1

0

0

1

1

0

2

3

1

0

9

3

0

.

.

.

.

.

.

.

.

.

.

.

1

3

0

0

2

0

0

0

.

.

.

.

.

TRAD_H_PSS

H

H

H

H

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

E

E

.

.

.

C

C

C

C

C

C

C

C

C

C

C

C

C

.

C

C

C

TRAD_H_Seq

R

C

L

S

C

I

L

A

Q

Q

P

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

N

L

K

.

.

.

C

G

S

G

A

R

G

G

D

G

E

V

A

.

S

A

P

-------

-

+

K

-

G

-

-

G

+

-

+

-

+

-

A

P

1ad5B3_Seq

.

.

.

.

.

.

.

.

.

N

Y

I

H

R

D

L

R

A

A

N

I

L

V

S

A

S

L

V

C

K

I

A

D

F

G

L

A

R

V

G

A

K

F

P

I

K

W

T

A

P

1ad5B3_SS

.

.

.

.

.

.

.

.

.

C

C

C

C

C

C

C

C

C

C

C

E

E

E

E

C

C

C

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

C

C

H

CORE

.

.

.

.

.

.

.

.

.

0

0

0

0

0

0

8

0

5

0

0

8

0

3

0

0

0

0

0

5

0

7

0

0

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

H

H

TRAD_H_Seq

L

Q

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

A

Q

T

F

L

F

Q

G

Q

P

V

V

N

R

P

L

S

L

K

D

Q

Q

T

F

A

R

S

V

G

L

K

-------

-

-

-

-

-

-

+

+

-

+

+

-

P

-

G

+

+

1ad5B3_Seq

E

A

I

N

F

G

S

F

T

I

K

S

D

V

W

S

F

G

I

L

L

M

E

I

V

T

Y

G

.

.

.

R

I

P

Y

P

.

.

.

.

.

.

.

.

.

.

.

G

M

S

1ad5B3_SS

H

H

H

H

H

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

.

.

.

C

C

C

C

C

.

.

.

.

.

.

.

.

.

.

.

C

C

C

CORE

0

0

0

0

0

0

0

0

0

0

0

0

0

2

0

1

5

0

0

7

2

0

0

5

1

0

0

0

.

.

.

0

0

0

0

0

.

.

.

.

.

.

.

.

.

.

.

0

0

0

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

.

C

C

TRAD_H_Seq

W

R

K

V

G

R

S

L

Q

R

G

C

R

A

L

R

D

P

A

L

D

S

L

A

Y

E

Y

E

R

E

G

L

Y

E

Q

A

F

Q

L

L

R

R

F

V

Q

A

E

.

G

R

-------

-

+

V

-

R

L

R

G

R

P

-

-

E

+

-

E

+

+

+

+

+

R

-

+

-

+

-

1ad5B3_Seq

N

P

E

V

I

R

A

L

E

R

G

.

.

.

Y

R

M

P

.

.

.

.

.

.

.

.

.

R

P

E

N

C

P

E

E

L

Y

N

I

M

M

R

C

W

K

N

R

P

E

E

1ad5B3_SS

C

H

H

H

H

H

H

H

H

H

C

.

.

.

C

C

C

C

.

.

.

.

.

.

.

.

.

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

CORE

0

0

0

0

0

0

0

0

0

0

0

.

.

.

0

0

0

0

.

.

.

.

.

.

.

.

.

0

0

0

0

0

0

0

0

2

0

0

1

0

0

0

2

0

0

0

0

0

0

0

TRAD_H_PSS

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

TRAD_H_Seq

R

A

T

L

Q

R

L

V

E

A

L

E

E

N

E

L

T

S

L

A

E

D

L

L

G

L

T

D

P

N

G

G

L

A

-------

R

-

T

-

+

+

-

L

D

+

-

-

T

+

+

-

-

-

-

-

1ad5B3_Seq

R

P

T

F

E

Y

I

Q

S

V

L

D

.

.

.

.

.

.

.

.

.

D

F

Y

T

A

T

E

S

Q

Q

Q

Q

P

1ad5B3_SS

C

C

C

H

H

H

H

H

H

H

H

H

.

.

.

.

.

.

.

.

.

H

C

C

C

E

C

C

C

C

C

C

C

C

CORE

0

0

0

3

0

0

3

0

0

0

4

0

.

.

.

.

.

.

.

.

.

0

0

0

0

0

0

0

0

0

0

0

0

0