Alignment of TRAD_HUMAN_whole with 1a06-0

Alignment of TRAD_HUMAN_whole with 1a06-0

PSSM Score Key
-10																			10

Bad																			Good

TRAD_H_PSS	Predicted Secondary Structure for your Sequence
TRAD_H_Seq	Your Sequence
1a06-0_Seq	Library Sequence
1a06-0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

TRAD_H_PSS

C

C

C

C

C

C

C

H

H

H

H

E

E

E

E

E

E

E

E

E

C

H

H

H

H

H

H

H

H

C

C

C

C

C

C

H

H

H

H

H

H

.

.

.

H

H

H

H

H

H

TRAD_H_Seq

M

A

A

G

Q

N

G

H

E

E

W

V

G

S

A

Y

L

F

V

E

S

S

L

D

K

V

V

L

S

D

A

Y

A

H

P

Q

Q

K

V

A

V

.

.

.

Y

R

A

L

Q

A

-------

-

-

+

+

-

-

+

+

+

-

-

-

-

L

-

+

-

+

-

-

+

V

-

L

-

-

-

-

Q

+

+

V

A

+

-

+

-

-

1a06-0_Seq

W

K

Q

A

E

D

I

R

D

I

Y

D

F

R

D

V

L

.

G

T

G

A

F

S

E

V

I

L

A

E

D

.

K

R

T

Q

K

L

V

A

I

K

C

I

A

K

E

N

E

I

1a06-0_SS

C

E

E

C

C

C

H

H

H

C

E

E

E

E

E

E

C

.

E

C

H

H

H

H

H

E

E

E

E

E

E

.

C

C

C

C

C

E

E

E

E

E

E

E

E

C

H

H

H

H

CORE

0

0

0

0

0

0

2

0

0

0

0

0

1

0

0

0

6

.

0

0

0

0

2

0

0

2

1

5

2

0

0

.

0

0

0

0

0

3

1

5

2

0

0

1

0

0

0

0

0

2

TRAD_H_PSS

H

H

H

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

E

E

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

H

TRAD_H_Seq

A

L

A

E

S

G

G

S

P

D

V

L

Q

M

L

K

I

H

R

S

D

P

Q

L

I

V

Q

L

R

F

C

G

R

Q

P

C

G

R

F

L

R

A

Y

R

E

G

X

X

X

X

-------

A

+

-

-

-

P

-

+

+

+

-

I

-

S

-

-

L

-

+

-

+

+

+

G

-

-

L

-

+

-

-

1a06-0_Seq

A

V

L

H

K

I

K

H

P

N

I

V

A

L

D

D

I

Y

E

S

G

G

H

L

Y

L

I

M

Q

L

V

S

.

.

.

.

G

G

E

L

F

D

R

I

V

E

K

G

F

Y

1a06-0_SS

H

H

H

H

H

C

C

C

C

C

E

C

C

E

E

E

E

E

E

E

C

C

E

E

E

E

E

E

C

C

C

C

.

.

.

.

C

E

E

H

H

H

H

H

H

H

C

C

C

C

CORE

0

0

0

0

0

2

0

0

0

0

4

1

0

1

0

0

1

0

0

0

0

0

0

1

0

1

2

1

0

5

2

1

.

.

.

.

1

2

0

5

2

0

0

4

0

0

0

0

0

1

TRAD_H_PSS		H	H	H	H	H	H	H	H	H	H		C	C	C	C	C	C	E	E	E	E		E	C	C	C	H	H	H	H	H	H		H	C	C	C	C	H	H	H	H	H		H	H	H	H	C	C	C	C	C	H
TRAD_H_Seq		X	X	X	X	X	X	X	X	X	X		X	X	H	S	V	P	L	Q	L	E		L	R	A	G	A	E	R	L	D	A		L	L	A	D	E	E	R	C	L	S		C	I	L	A	Q	Q	P	X	X	X
-------																													+	-	L	D	A		+
1a06-0_Seq		T	E	R	D	A	S	R	L	I	F		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	Q	V	L	D	A		V	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.
1a06-0_SS		E	H	H	H	H	H	H	H	H	H		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	H	H	H	H	H		H	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.
CORE		0	0	0	0	4	2	0	5	8	1		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	0	8	8	0	3		6	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

E

E

E

E

E

E

E

C

C

C

.

.

.

C

C

C

C

C

C

C

.

.

.

.

.

.

.

C

C

C

C

C

C

H

H

H

H

H

H

H

H

TRAD_H_Seq

X

X

X

X

X

X

X

X

X

X

X

X

X

N

L

K

C

G

S

.

.

.

G

A

R

G

G

D

G

.

.

.

.

.

.

.

E

V

A

S

A

P

L

Q

X

X

X

X

X

X

-------

L

K

+

D

-

-

-

-

-

A

P

-

-

1a06-0_Seq

.

.

K

Y

L

H

D

L

G

I

V

H

R

D

L

K

P

E

N

L

L

Y

Y

S

L

D

E

D

S

K

I

M

I

S

D

F

P

G

Y

V

A

P

E

V

L

A

Q

K

P

Y

1a06-0_SS

.

.

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

E

E

E

C

C

C

C

C

C

C

C

E

E

E

C

C

C

C

C

C

C

C

H

H

H

H

H

C

C

C

C

CORE

.

.

0

0

2

0

0

0

0

1

0

0

0

0

7

0

2

0

0

6

2

1

0

0

1

0

0

0

0

0

5

0

7

1

0

2

0

1

1

0

0

0

0

0

0

0

0

0

0

0

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

.

C

C

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

X

X

X

X

X

X

X

X

X

X

X

A

Q

T

F

L

F

Q

G

Q

P

V

V

N

R

P

L

S

.

L

K

D

Q

Q

T

F

A

R

S

V

G

L

K

W

R

K

V

G

R

S

-------

-

-

-

-

L

-

-

G

+

P

P

-

D

+

+

+

F

-

+

-

-

1a06-0_Seq

S

K

A

V

D

C

W

S

I

G

V

I

A

Y

I

L

L

C

G

Y

P

.

.

.

.

P

F

Y

D

E

N

D

A

K

L

F

E

Q

I

L

K

.

.

.

.

.

.

.

.

.

1a06-0_SS

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

.

.

.

.

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

C

.

.

.

.

.

.

.

.

.

CORE

0

0

0

0

0

2

0

1

9

2

1

5

6

0

1

6

3

0

0

0

0

.

.

.

.

1

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

.

.

.

.

.

.

.

.

.

TRAD_H_PSS

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

.

C

C

C

C

H

H

H

H

H

TRAD_H_Seq

L

Q

R

G

C

R

A

L

R

D

P

A

L

D

S

L

A

Y

E

Y

E

R

E

G

L

Y

E

Q

A

F

Q

L

L

R

R

F

V

Q

A

E

.

G

R

R

A

T

L

Q

R

L

-------

+

-

-

-

-

+

P

-

+

D

+

-

+

A

-

+

+

R

+

-

+

+

+

R

-

T

+

+

-

+

1a06-0_Seq

.

.

.

A

E

Y

E

F

D

S

P

Y

W

D

D

I

S

D

S

.

.

.

.

.

.

.

.

.

A

K

D

F

I

R

H

L

M

E

K

D

P

E

K

R

F

T

C

E

Q

A

1a06-0_SS

.

.

.

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

C

C

C

C

H

H

H

C

C

C

H

H

H

H

CORE

.

.

.

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

.

.

.

.

.

.

.

.

.

2

0

0

6

3

0

0

6

1

0

0

0

0

0

0

0

2

0

5

0

0

7

TRAD_H_PSS

H

H

.

.

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

.

.

.

.

.

.

.

.

TRAD_H_Seq

V

E

.

.

.

.

.

.

.

.

.

.

.

A

L

E

E

N

E

L

T

S

L

A

E

D

L

L

G

L

T

D

P

N

G

G

L

A

.

.

.

.

.

.

.

.

-------

-

+

+

+

+

+

-

-

-

+

+

-

-

-

-

-

1a06-0_Seq

L

Q

H

P

W

I

A

G

D

T

A

L

D

K

N

I

H

Q

S

V

S

E

Q

I

K

K

N

F

A

K

S

K

W

K

Q

A

F

N

A

T

A

V

V

R

H

M

1a06-0_SS

H

H

C

C

C

C

C

C

C

C

C

C

C

C

E

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

E

C

H

H

H

H

H

H

H

C

CORE

3

0

0

0

2

5

0

0

0

0

1

0

0

0

0

1

0

0

0

1

0

0

0

1

0

0

0

1

0

0

0

0

0

0

0

0

3

0

1

0

1

6

0

0

0

0