Alignment of thymidine_kinase with 1zip--

Alignment of thymidine_kinase with 1zip--

PSSM Score Key
-10																			10

Bad																			Good

thymid_PSS	Predicted Secondary Structure for your Sequence
thymid_Seq	Your Sequence
1zip--_Seq	Library Sequence
1zip--_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

thymid_PSS

C

C

.

.

C

C

C

C

C

C

C

C

C

C

C

.

.

.

.

.

.

C

C

C

C

C

E

E

E

E

E

E

E

E

E

C

C

C

C

H

H

H

H

.

.

.

H

H

H

H

thymid_Seq

M

S

.

.

C

I

N

L

P

T

V

L

P

G

S

.

.

.

.

.

.

P

S

K

T

R

G

Q

I

Q

V

I

L

G

P

M

F

S

G

K

S

T

E

.

.

.

L

M

R

R

-------

M

-

-

+

-

L

P

-

-

-

G

-

-

-

-

-

-

+

I

-

-

G

-

M

F

-

-

-

-

E

L

-

+

1zip--_Seq

M

N

L

V

L

M

G

L

P

G

A

G

K

G

T

Q

A

E

K

I

V

A

A

Y

G

I

P

H

I

S

.

.

T

G

D

M

F

R

A

A

M

K

E

G

T

P

L

G

L

Q

1zip--_SS

C

E

E

E

E

E

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

.

.

H

H

H

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

CORE

4

0

7

5

9

2

0

1

0

0

3

1

0

0

0

1

5

0

0

9

3

0

0

0

0

5

0

0

4

0

.

.

2

0

0

2

1

0

0

0

0

0

0

0

0

0

1

0

0

0

thymid_PSS		H	H	H	H	H	H	C	C	C	E		E	E	E	E	E	E	C	C	C	C		C	C	C	C	C	E	E	E	E	C		C	C	C	C	C	C	C	C	C	C		C	H	H	H	H	H	.	H	H	H
thymid_Seq		V	R	R	F	Q	I	A	Q	Y	K		C	L	V	I	K	Y	A	K	D	T		R	Y	S	S	S	F	C	T	H	D		R	N	T	M	E	A	L	P	A	C		L	L	R	D	V	A	.	Q	E	A
-------					+	-	-	+	-																														+	-		P	-	-		+		-	+		-		+	+	-
1zip--_Seq		A	K	Q	Y	M	D	R	G	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	D	L	V	P	D	E		V	T	I	G	I	V	R	E	R	L
1zip--_SS		H	H	H	H	H	H	H	C	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	C	C	C	C	H	H		H	H	H	H	H	H	H	H	H	H
CORE		1	0	0	0	0	0	0	0	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	0	0	1	0	0	0		0	1	1	0	1	5	0	0	0	6

thymid_PSS

C

C

E

E

E

.

.

.

E

E

E

E

C

C

C

C

C

C

H

H

H

.

.

H

H

H

H

H

H

.

H

H

C

C

C

E

E

E

E

E

C

C

C

C

.

.

.

.

C

H

thymid_Seq

L

G

V

A

V

.

.

.

I

G

I

D

E

G

Q

F

F

P

D

I

M

.

.

E

F

C

E

A

M

.

A

N

A

G

K

T

V

I

V

A

A

L

D

G

.

.

.

.

T

F

-------

-

-

-

-

+

D

-

F

-

-

-

+

-

E

+

-

E

M

A

G

-

L

D

-

-

-

1zip--_Seq

S

K

D

D

C

Q

N

G

F

L

L

D

.

.

G

F

P

R

T

V

A

Q

A

E

A

L

E

T

M

L

A

D

I

G

R

K

.

.

.

.

.

L

D

Y

V

I

H

I

D

V

1zip--_SS

H

C

H

H

H

C

C

C

E

E

E

E

.

.

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

.

.

.

.

.

C

C

E

E

E

E

E

E

C

CORE

0

0

0

0

2

0

0

1

3

8

6

1

.

.

0

3

2

0

0

0

0

0

2

0

0

8

0

0

2

3

0

0

1

0

0

0

.

.

.

.

.

5

0

1

3

7

0

7

0

2

thymid_PSS

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

H

C

C

C

C

C

E

E

E

.

.

E

E

C

C

C

C

E

E

.

.

.

.

thymid_Seq

Q

R

K

P

F

G

A

I

L

N

L

V

P

L

A

E

S

V

V

K

L

T

A

V

C

M

E

C

F

R

E

A

A

Y

T

K

.

.

R

L

G

T

E

K

E

V

.

.

.

.

-------

-

+

-

-

L

-

E

-

+

-

-

+

C

-

C

-

A

Y

-

+

-

-

-

+

-

-

V

1zip--_Seq

R

Q

.

.

.

.

.

.

.

.

.

D

V

L

M

E

R

L

T

G

.

R

R

I

C

R

N

C

G

.

.

A

T

Y

H

L

I

F

H

P

P

A

K

P

G

V

C

D

K

C

1zip--_SS

C

H

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

H

.

E

E

E

E

C

C

C

C

.

.

C

E

E

E

C

C

C

E

C

C

C

E

C

C

E

C

C

C

C

CORE

0

0

.

.

.

.

.

.

.

.

.

0

0

2

0

0

0

1

0

0

.

0

0

0

1

0

0

0

0

.

.

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

thymid_PSS

.

.

E

E

E

C

C

C

C

C

C

H

H

.

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

.

.

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

thymid_Seq

.

.

E

V

I

G

G

A

D

K

Y

H

S

.

V

C

R

L

C

Y

F

K

K

A

S

G

Q

P

A

G

P

.

.

D

N

K

E

N

C

P

V

P

G

K

P

G

E

A

V

A

-------

E

+

-

A

D

-

-

-

V

-

-

-

-

-

-

+

-

+

P

-

-

-

-

+

K

-

+

-

-

-

-

-

+

+

-

1zip--_Seq

G

G

E

L

Y

Q

R

A

D

D

N

E

A

T

V

A

N

R

L

E

V

N

M

K

Q

M

K

P

L

V

D

F

Y

E

Q

K

G

Y

L

R

N

I

N

G

E

Q

D

M

.

.

1zip--_SS

C

C

E

E

E

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

E

E

E

E

E

C

C

C

C

H

.

.

CORE

0

0

0

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

0

0

0

0

0

0

1

1

0

0

2

0

0

0

0

0

2

0

0

6

0

2

0

0

0

0

.

.

thymid_PSS

H

H

H

H

C

C

C

H

H

H

H

C

C

C

C

C

C

thymid_Seq

A

R

K

L

F

A

P

Q

Q

I

L

Q

C

S

P

A

N

-------

-

K

F

A

-

-

+

-

L

-

-

-

A

1zip--_Seq

.

E

K

V

F

A

D

I

R

E

L

L

G

G

L

A

R

1zip--_SS

.

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

CORE

.

0

0

3

1

0

0

8

0

0

3

6

0

0

2

0

0