Alignment of thymidine_kinase with 1scuA1

Alignment of thymidine_kinase with 1scuA1

PSSM Score Key
-10																			10

Bad																			Good

thymid_PSS	Predicted Secondary Structure for your Sequence
thymid_Seq	Your Sequence
1scuA1_Seq	Library Sequence
1scuA1_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

thymid_PSS

C

C

C

C

C

C

.

.

C

C

.

.

.

.

.

C

C

C

C

C

C

C

C

C

C

E

E

E

E

E

E

E

E

E

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

thymid_Seq

M

S

C

I

N

L

.

.

P

T

.

.

.

.

.

V

L

P

G

S

P

S

K

T

R

G

Q

I

Q

V

I

L

G

P

M

F

S

G

K

S

T

E

L

M

R

R

V

R

R

F

-------

C

+

P

-

+

+

P

G

-

-

-

K

-

G

+

-

-

-

-

-

-

+

-

+

E

+

-

-

+

-

1scuA1_Seq

.

N

C

P

G

V

I

T

P

G

E

C

K

I

G

I

Q

P

G

H

I

H

K

P

.

G

K

V

G

.

.

I

V

S

R

S

G

T

L

T

Y

E

A

V

K

Q

T

T

D

Y

1scuA1_SS

.

C

C

C

E

E

E

E

C

C

C

E

E

E

E

C

C

C

C

C

C

C

C

C

.

C

C

E

E

.

.

E

E

E

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

CORE

.

0

0

0

1

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

.

1

0

5

5

.

.

5

9

3

0

0

0

0

3

1

0

0

5

2

0

0

3

0

0

0

thymid_PSS		H	H	C	C	C	E	E	E	E	E		E	E	C	C	C	C	C	C	C	C		C	E	E	E	E	C	C	C	C	C		C	C	C	C	C	C	C	H	H	H		H	H	H	H	H	C	C	E	E	E
thymid_Seq		Q	I	A	Q	Y	K	C	L	V	I		K	Y	A	K	D	T	R	Y	S	S		S	F	C	T	H	D	R	N	T	M		E	A	L	P	A	C	L	L	R	D		V	A	Q	E	A	L	G	V	A	V
-------																					-	-			-	-	T	-	-	-	-	-	-		-			P
1scuA1_Seq		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	G	F		G	Q	S	T	C	V	G	I	G	G		D	P	I	P	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.
1scuA1_SS		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	C	C		C	E	E	E	E	E	E	C	C	C		C	C	C	C	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.
CORE		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	0	2		1	1	3	1	2	5	1	4	0	0		0	0	0	0	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.

thymid_PSS

E

E

E

E

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

E

E

C

C

C

C

C

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

thymid_Seq

I

G

I

D

E

G

Q

F

F

P

D

I

M

E

F

C

E

A

M

A

N

A

G

K

T

V

I

V

A

A

L

D

G

T

F

Q

R

K

P

F

G

A

I

L

N

L

V

P

L

A

-------

G

-

F

-

D

I

E

-

-

E

-

-

+

-

-

-

-

V

+

-

-

-

G

-

-

-

-

-

-

A

1scuA1_Seq

.

.

.

.

.

G

S

N

F

I

D

I

L

E

M

F

E

K

D

P

Q

T

E

A

I

V

M

I

.

.

.

.

.

.

.

.

G

E

I

.

G

G

S

A

E

E

E

A

.

A

1scuA1_SS

.

.

.

.

.

C

C

C

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

E

E

E

E

E

.

.

.

.

.

.

.

.

E

E

C

.

C

C

H

H

H

H

H

H

.

H

CORE

.

.

.

.

.

0

0

0

5

1

0

4

6

0

0

5

0

0

0

0

0

2

0

1

7

9

9

4

.

.

.

.

.

.

.

.

3

0

4

.

0

0

0

1

1

0

0

7

.

2

thymid_PSS

H

H

H

H

H

.

.

.

C

C

H

H

H

H

H

H

C

C

C

C

C

E

E

E

E

E

C

C

C

C

E

E

E

E

E

C

C

C

C

C

C

H

H

H

H

H

H

H

C

C

thymid_Seq

E

S

V

V

K

.

.

.

L

T

A

V

C

M

E

C

F

R

E

A

A

Y

T

K

R

L

G

T

E

K

E

V

E

V

I

G

G

A

D

K

Y

H

S

V

C

R

L

C

Y

F

-------

+

-

+

-

+

-

-

-

V

+

-

-

-

-

-

A

-

-

-

K

R

G

-

-

-

-

-

-

G

G

-

-

1scuA1_Seq

A

Y

I

K

E

H

V

T

K

P

V

V

G

Y

I

A

G

V

T

A

P

K

G

K

R

M

G

H

A

G

A

I

I

.

A

G

G

K

G

.

.

.

.

.

.

.

.

.

.

.

1scuA1_SS

H

H

H

H

H

C

C

C

C

C

E

E

E

E

E

E

C

C

C

C

C

C

C

E

E

C

C

C

C

C

C

E

E

.

C

C

C

C

C

.

.

.

.

.

.

.

.

.

.

.

CORE

0

0

6

0

0

0

2

0

0

1

6

9

4

1

3

2

1

1

0

3

0

0

0

0

0

2

0

0

0

0

2

0

2

.

0

0

0

0

1

.

.

.

.

.

.

.

.

.

.

.

thymid_PSS

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

C

C

C

C

C

C

thymid_Seq

K

K

A

S

G

Q

P

A

G

P

D

N

K

E

N

C

P

V

P

G

K

P

G

E

A

V

A

A

R

K

L

F

A

P

Q

Q

I

L

Q

C

S

P

A

N

-------

-

A

-

-

-

+

+

-

-

-

-

+

-

K

+

-

-

A

+

+

-

+

L

+

-

+

+

1scuA1_Seq

.

.

.

.

.

.

T

A

D

E

K

F

A

A

L

E

A

A

G

V

K

T

V

R

S

L

A

.

.

D

I

.

.

.

G

E

A

L

K

.

T

V

L

K

1scuA1_SS

.

.

.

.

.

.

C

H

H

H

H

H

H

H

H

H

H

H

C

C

E

E

C

C

C

H

H

.

.

H

H

.

.

.

H

H

H

H

H

.

H

H

H

C

CORE

.

.

.

.

.

.

0

4

0

0

0

2

0

0

4

0

0

2

0

5

0

2

6

0

0

1

0

.

.

0

6

.

.

.

0

0

5

6

0

.

0

3

1

0