Alignment of thymidine_kinase with 1rahC-

Alignment of thymidine_kinase with 1rahC-

PSSM Score Key
-10																			10

Bad																			Good

thymid_PSS	Predicted Secondary Structure for your Sequence
thymid_Seq	Your Sequence
1rahC-_Seq	Library Sequence
1rahC-_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

thymid_PSS

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

E

E

E

E

E

E

E

E

E

C

C

C

C

H

H

.

H

H

H

H

H

H

H

H

H

H

H

H

C

.

.

.

thymid_Seq

M

S

C

I

N

L

P

T

V

L

P

G

S

P

S

K

T

R

G

Q

I

Q

V

I

L

G

P

M

F

S

G

K

S

.

T

E

L

M

R

R

V

R

R

F

Q

I

A

.

.

.

-------

P

-

+

-

+

-

I

-

I

+

S

-

-

+

+

-

+

+

+

+

1rahC-_Seq

.

.

.

.

.

.

.

.

.

.

.

A

N

P

L

Y

Q

K

.

H

I

I

S

I

N

D

.

.

L

S

R

D

D

L

N

L

V

L

A

T

A

A

K

L

K

A

N

P

Q

P

1rahC-_SS

.

.

.

.

.

.

.

.

.

.

.

C

C

C

C

C

C

C

.

C

E

C

C

H

H

H

.

.

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

CORE

.

.

.

.

.

.

.

.

.

.

.

0

0

0

6

0

0

0

.

0

6

2

0

4

0

0

.

.

5

0

0

0

0

5

0

2

6

3

0

2

2

0

0

3

0

0

0

0

0

0

thymid_PSS

.

.

.

C

C

E

E

E

E

E

E

E

C

C

C

.

C

C

C

C

C

C

E

.

.

.

.

.

.

.

.

.

.

.

.

.

E

E

E

C

C

C

C

C

C

C

C

C

C

C

thymid_Seq

.

.

.

Q

Y

K

C

L

V

I

K

Y

A

K

D

.

T

R

Y

S

S

S

F

.

.

.

.

.

.

.

.

.

.

.

.

.

C

T

H

D

R

N

T

M

E

A

L

P

A

C

-------

+

-

K

-

+

+

-

+

+

T

R

-

S

F

-

-

N

T

-

-

-

-

-

-

1rahC-_Seq

E

L

L

K

H

K

V

I

A

S

C

F

F

E

A

S

T

R

T

R

L

S

F

E

T

S

M

H

R

L

G

A

S

V

V

G

F

S

D

S

A

N

T

S

L

G

K

K

G

E

1rahC-_SS

C

C

C

C

C

C

E

E

E

E

E

E

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

CORE

0

2

5

0

0

0

1

7

4

1

3

2

2

0

0

0

0

0

1

0

0

0

4

0

0

0

4

0

0

4

0

5

0

1

1

0

1

0

0

0

0

0

0

0

1

0

0

0

0

0

thymid_PSS		C	H	H	H	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	H	H		H	H	H	C	C	E	E	E	E	.		E	E	E	C	C	C	C	C	C	.
thymid_Seq		L	L	R	D	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	V	A		Q	E	A	L	G	V	A	V	I	.		G	I	D	E	G	Q	F	F	P	.
-------		-	L	+	D																											-	+		+		+	-	+	V	-	V	+			+	-	D	-	-	-	+	-	P
1rahC-_Seq		T	L	A	D	T	I	S	V	I	S		T	Y	V	D	A	I	V	M	R	H		P	Q	E	G	A	A	R	L	A	T		E	F	S	G	N	V	P	V	L	N		A	G	D	G	S	N	Q	H	P	T
1rahC-_SS		C	H	H	H	H	H	H	H	H	H		C	C	C	C	E	E	E	E	E	E		C	C	E	C	H	H	H	H	H	H		H	C	C	C	C	C	C	E	E	E		E	E	E	C	C	C	E	C	H	H
CORE		0	2	0	0	0	4	0	0	3	2		0	0	2	0	4	6	8	4	0	0		0	0	0	0	2	4	0	0	4	1		0	0	4	0	0	3	1	6	7	0		4	0	0	0	0	0	0	0	2	1

thymid_PSS

.

.

.

.

H

H

H

H

H

H

H

H

H

H

H

.

C

C

C

E

E

E

E

E

C

C

C

C

C

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

thymid_Seq

.

.

.

.

D

I

M

E

F

C

E

A

M

A

N

.

A

G

K

T

V

I

V

A

A

L

D

G

T

F

Q

R

K

P

F

G

A

I

L

N

L

V

P

L

A

E

S

V

V

K

-------

D

+

+

-

E

-

-

-

-

+

+

V

-

-

-

D

+

-

-

G

-

+

-

-

A

-

1rahC-_Seq

Q

T

L

L

D

L

F

T

I

Q

E

T

Q

G

R

L

D

N

L

H

V

A

M

V

G

.

D

L

.

.

.

.

.

K

Y

G

R

T

V

H

S

L

T

Q

A

L

A

K

F

D

1rahC-_SS

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

E

E

E

E

E

C

.

C

C

.

.

.

.

.

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

CORE

0

2

6

0

0

5

1

0

3

0

0

0

0

0

0

3

0

0

1

0

1

5

2

5

0

.

0

1

.

.

.

.

.

0

0

0

0

0

2

0

1

3

2

0

5

3

1

0

1

0

thymid_PSS

C

C

.

.

.

.

.

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

C

C

C

C

C

E

E

E

E

E

C

C

C

C

E

E

E

E

E

C

C

C

C

.

.

.

.

.

thymid_Seq

L

T

.

.

.

.

.

.

.

.

.

.

.

.

.

.

A

V

C

M

E

C

F

R

E

A

A

Y

T

K

R

L

G

T

E

K

E

V

E

V

I

G

G

A

D

.

.

.

.

.

-------

-

+

-

-

+

+

+

-

+

-

+

+

-

-

-

E

V

+

-

+

+

D

1rahC-_Seq

G

N

R

F

Y

F

I

A

P

D

A

L

A

M

P

Q

Y

I

L

D

M

L

.

.

D

E

K

G

I

A

W

S

L

H

S

S

I

E

E

V

M

A

E

V

D

I

L

Y

M

T

1rahC-_SS

C

C

E

E

E

E

E

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

.

.

H

H

H

C

C

C

E

E

E

C

C

C

H

H

H

C

H

H

H

C

C

E

E

E

E

C

CORE

0

0

0

2

0

2

3

1

0

0

0

0

0

2

0

0

0

1

1

0

0

2

.

.

0

0

0

0

1

0

0

0

0

0

0

0

5

0

0

2

5

0

0

2

0

1

9

0

4

0

thymid_PSS

.

.

.

.

C

C

H

H

H

H

H

H

H

C

C

C

C

C

C

C

.

.

.

.

.

.

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

.

.

.

.

.

.

.

thymid_Seq

.

.

.

.

K

Y

H

S

V

C

R

L

C

Y

F

K

K

A

S

G

.

.

.

.

.

.

Q

P

A

G

P

D

N

K

E

N

C

P

V

P

G

K

P

.

.

.

.

.

.

.

-------

-

-

+

-

+

-

+

-

-

+

K

-

+

-

-

A

+

+

-

K

-

-

-

P

-

P

-

1rahC-_Seq

R

V

Q

K

E

R

L

D

P

S

E

Y

A

N

V

K

A

Q

F

V

L

R

A

S

D

L

H

N

A

K

A

N

M

K

V

L

H

P

L

P

R

V

D

E

I

A

T

D

V

D

1rahC-_SS

C

C

C

C

C

C

C

C

H

H

H

H

H

C

C

C

C

C

C

C

E

C

H

H

H

H

C

C

C

C

C

C

C

E

E

E

C

C

C

C

C

C

C

C

E

C

H

H

H

C

CORE

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

9

0

2

0

0

8

0

0

1

0

0

0

3

0

9

1

0

0

0

0

0

0

0

0

4

0

0

0

6

0

thymid_PSS

.

.

.

.

.

.

.

.

.

.

.

C

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

C

C

C

C

C

C

thymid_Seq

.

.

.

.

.

.

.

.

.

.

.

G

E

A

V

A

A

R

K

L

F

A

P

Q

Q

I

L

Q

C

S

P

A

N

-------

G

-

-

+

A

R

+

-

-

-

-

L

-

-

-

-

-

1rahC-_Seq

K

T

P

H

A

W

Y

F

Q

Q

A

G

N

G

I

F

A

R

Q

A

.

L

L

A

L

V

L

N

R

D

L

V

L

1rahC-_SS

C

C

C

C

E

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

.

H

H

H

H

H

H

C

C

C

C

C

C

CORE

0

1

0

0

1

0

1

0

0

0

0

0

0

0

0

1

2

0

0

4

.

6

8

4

4

4

4

0

0

0

2

0

0