Alignment of thymidine_kinase with 1ofgC1

Alignment of thymidine_kinase with 1ofgC1

PSSM Score Key
-10																			10

Bad																			Good

thymid_PSS	Predicted Secondary Structure for your Sequence
thymid_Seq	Your Sequence
1ofgC1_Seq	Library Sequence
1ofgC1_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

thymid_PSS

.

.

.

.

.

.

.

.

.

.

.

.

.

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

E

E

E

E

E

E

E

E

E

C

C

C

C

H

H

H

H

H

H

thymid_Seq

.

.

.

.

.

.

.

.

.

.

.

.

.

M

S

C

I

N

L

P

T

V

L

P

G

S

P

S

K

T

R

G

Q

I

Q

V

I

L

G

P

M

F

S

G

K

S

T

E

L

M

-------

-

-

-

-

+

P

-

+

-

-

-

P

-

R

+

-

-

G

K

1ofgC1_Seq

A

T

L

P

A

G

A

S

Q

V

P

T

T

P

A

G

R

P

M

P

Y

A

I

R

P

M

P

E

D

R

R

.

.

.

.

F

G

Y

A

I

V

G

L

G

K

.

.

.

.

.

1ofgC1_SS

C

C

C

C

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

.

.

.

.

E

E

E

E

E

E

C

C

C

H

.

.

.

.

.

CORE

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

.

.

.

.

2

1

1

7

9

8

4

6

0

0

.

.

.

.

.

thymid_PSS		H	H	H	H	H	H	H	H	C	C		C	E	E	E	E	E	E	E	C	C		C	C	C	C	C	C	C	E	E	E		.	.	E	C	C	C	.	.	.	.		.	.	.	.	.	.	.	C	C	C
thymid_Seq		R	R	V	R	R	F	Q	I	A	Q		Y	K	C	L	V	I	K	Y	A	K		D	T	R	Y	S	S	S	F	C	T		.	.	H	D	R	N	.	.	.	.		.	.	.	.	.	.	.	T	M	E
-------			-	-	+		+	-	+	-			-												-		-	-	-	S	+	-	-				-	+	+	N
1ofgC1_Seq		.	Y	A	L	N	Q	I	L	P	G		F	.	.	.	.	.	.	.	.	.		.	A	G	C	Q	H	S	R	I	E		A	L	V	S	G	N	A	E	K	A		K	I	V	A	A	E	Y	G	V	D
1ofgC1_SS		.	H	H	H	H	H	C	C	C	C		C	.	.	.	.	.	.	.	.	.		.	C	C	C	C	C	E	E	E	E		E	E	E	C	C	C	H	H	H	H		H	H	H	H	H	H	H	C	C	C
CORE		.	1	5	2	0	0	5	7	0	1		3	.	.	.	.	.	.	.	.	.		.	0	0	1	0	0	3	0	5	0		3	8	6	2	0	0	0	0	0	3		0	0	5	5	0	0	0	0	4	0

thymid_PSS

C

C

C

.

.

C

C

C

H

H

H

H

H

H

H

H

C

C

E

E

E

E

E

E

E

C

C

C

C

C

C

H

.

.

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

thymid_Seq

A

L

P

.

.

A

C

L

L

R

D

V

A

Q

E

A

L

G

V

A

V

I

G

I

D

E

G

Q

F

F

P

D

.

.

I

M

E

F

C

E

A

M

A

N

A

G

K

T

V

I

-------

+

+

+

+

-

-

-

D

-

+

+

+

+

-

+

+

-

I

-

P

-

-

-

E

F

+

+

+

-

A

G

K

V

+

1ofgC1_Seq

P

R

K

I

Y

D

Y

S

N

F

D

K

I

A

K

D

P

K

I

D

A

V

Y

I

.

.

.

.

I

L

P

N

S

L

H

A

E

F

A

I

R

A

F

K

A

G

K

H

V

M

1ofgC1_SS

H

H

H

E

E

C

C

C

C

H

H

H

H

H

H

C

C

C

C

C

E

E

E

E

.

.

.

.

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

E

E

E

CORE

0

0

0

3

1

0

1

0

0

5

0

0

3

0

0

0

0

0

3

0

3

9

2

7

.

.

.

.

5

4

0

0

0

0

1

3

0

4

7

1

0

7

3

0

1

0

0

0

9

3

thymid_PSS

E

E

C

C

C

C

C

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

H

C

C

C

C

C

E

E

E

E

E

C

C

C

C

thymid_Seq

V

A

A

L

D

G

T

F

Q

R

K

P

F

G

A

I

L

N

L

V

P

L

A

E

S

V

V

K

L

T

A

V

C

M

E

C

F

R

E

A

A

Y

T

K

R

L

G

T

E

K

-------

+

-

K

P

+

+

+

-

V

-

+

-

+

+

-

+

+

+

A

K

1ofgC1_Seq

C

.

.

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.

.

E

K

P

M

A

T

S

.

.

.

V

A

D

C

Q

R

M

I

D

.

.

.

.

.

.

.

A

A

K

A

A

N

.

.

.

.

.

.

.

.

K

1ofgC1_SS

E

.

.

.

.

.

.

.

.

C

C

C

C

C

C

C

.

.

.

H

H

H

H

H

H

H

H

H

.

.

.

.

.

.

.

H

H

H

H

H

C

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.

.

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.

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.

C

CORE

5

.

.

.

.

.

.

.

.

0

0

0

7

4

0

0

.

.

.

1

0

0

3

0

0

6

4

0

.

.

.

.

.

.

.

1

4

0

0

1

0

.

.

.

.

.

.

.

.

0

thymid_PSS

E

E

E

E

E

C

C

C

C

C

C

H

H

H

H

H

H

H

C

.

.

C

C

C

C

C

C

.

.

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

thymid_Seq

E

V

E

V

I

G

G

A

D

K

Y

H

S

V

C

R

L

C

Y

.

.

F

K

K

A

S

G

.

.

Q

P

A

G

P

D

N

K

E

N

C

P

V

P

G

K

P

G

E

A

V

-------

-

+

-

I

G

Y

C

-

Y

F

-

+

-

-

-

+

A

+

-

N

K

P

V

-

-

-

-

-

E

1ofgC1_Seq

K

L

M

.

I

G

.

.

.

.

Y

.

.

R

C

.

.

H

Y

N

Q

F

S

A

Q

L

D

H

L

A

E

A

V

I

N

N

K

.

.

.

P

V

R

S

P

G

E

E

G

M

1ofgC1_SS

C

E

E

.

E

C

.

.

.

.

C

.

.

H

H

.

.

H

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

.

.

.

C

C

C

C

E

H

H

H

H

H

CORE

0

9

2

.

4

1

.

.

.

.

0

.

.

0

0

.

.

0

0

0

0

1

0

0

0

4

0

0

3

2

0

0

0

0

0

0

0

.

.

.

0

1

0

1

0

4

0

0

2

2

thymid_PSS

H

.

H

H

H

H

C

C

C

H

H

H

H

C

C

C

.

.

.

.

.

.

.

.

.

.

.

.

C

C

C

thymid_Seq

A

.

A

R

K

L

F

A

P

Q

Q

I

L

Q

C

S

.

.

.

.

.

.

.

.

.

.

.

.

P

A

N

-------

-

R

-

+

-

A

-

-

+

-

-

-

-

-

1ofgC1_Seq

Q

D

V

R

L

I

Q

A

I

Y

E

A

A

R

T

G

R

P

V

N

T

D

W

G

Y

V

R

Q

G

G

Y

1ofgC1_SS

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

C

C

C

C

C

C

C

C

C

C

C

CORE

0

0

3

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0