Alignment of thymidine_kinase with 1mjhA0

Alignment of thymidine_kinase with 1mjhA0

PSSM Score Key
-10																			10

Bad																			Good

thymid_PSS	Predicted Secondary Structure for your Sequence
thymid_Seq	Your Sequence
1mjhA0_Seq	Library Sequence
1mjhA0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

thymid_PSS

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

E

E

E

E

E

E

E

E

E

C

C

C

C

H

H

H

H

H

.

H

H

H

H

H

H

H

H

H

C

C

C

E

thymid_Seq

M

S

C

I

N

L

P

T

V

L

P

G

S

P

S

K

T

R

G

Q

I

Q

V

I

L

G

P

M

F

S

G

K

S

T

E

L

.

M

R

R

V

R

R

F

Q

I

A

Q

Y

K

-------

-

-

-

I

L

-

P

-

-

-

-

+

+

E

-

-

V

-

-

F

-

-

-

+

-

1mjhA0_Seq

V

M

Y

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

K

K

I

L

Y

P

T

D

F

S

E

T

A

E

I

A

L

K

H

V

K

A

F

K

T

L

K

A

E

1mjhA0_SS

C

C

C

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

C

E

E

E

E

E

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

CORE

0

0

0

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

0

0

6

9

2

4

1

0

1

0

0

0

1

0

0

4

2

0

0

8

0

0

3

0

0

0

0

0

0

thymid_PSS

E

E

E

E

E

E

C

C

C

C

C

C

C

C

C

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

E

E

E

E

E

E

E

C

C

thymid_Seq

C

L

V

I

K

Y

A

K

D

T

R

Y

S

S

S

F

C

T

H

D

R

N

T

M

E

A

L

P

A

C

L

L

R

D

V

A

Q

E

A

L

G

V

A

V

I

G

I

D

E

G

-------

-

+

+

-

+

D

+

R

-

-

-

-

-

-

-

E

+

-

-

-

E

+

1mjhA0_Seq

E

V

I

L

L

H

V

I

D

E

R

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

E

I

K

V

E

E

F

E

N

E

L

K

N

.

.

.

K

L

T

E

E

A

1mjhA0_SS

E

E

E

E

E

E

E

E

E

H

H

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

H

C

C

H

H

H

H

H

H

H

H

H

H

.

.

.

H

H

H

H

H

H

CORE

0

7

5

4

7

0

3

1

0

0

0

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

0

0

0

0

0

0

0

0

0

0

0

0

0

.

.

.

0

0

0

0

0

1

thymid_PSS

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

.

.

.

C

E

E

E

E

E

C

C

C

C

C

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

thymid_Seq

Q

F

F

P

D

I

M

E

F

C

E

A

M

A

N

A

G

.

.

.

K

T

V

I

V

A

A

L

D

G

T

F

Q

R

K

P

F

G

A

I

L

N

L

V

P

L

A

E

S

V

-------

-

-

+

-

+

+

+

G

K

+

+

I

V

-

P

-

E

-

+

1mjhA0_Seq

K

.

.

N

K

M

E

N

I

K

K

E

L

E

D

V

G

F

K

V

K

D

I

I

V

V

G

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

I

P

H

.

E

E

I

1mjhA0_SS

H

.

.

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

E

E

E

E

E

E

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

C

H

H

.

H

H

H

CORE

0

.

.

0

0

1

0

0

2

0

0

0

7

0

0

0

0

5

0

4

0

0

3

1

3

0

0

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

0

0

0

.

0

0

9

thymid_PSS		H	H	C	C	H	H	H	H	H	H		C	C	C	C	C	E	E	E	E	E		C	C	C	C	E	E	E	E	E	C		C	C	C	C	C	H	H	H	H	H		H	H	C	C	C	C	C	C	C	C
thymid_Seq		V	K	L	T	A	V	C	M	E	C		F	R	E	A	A	Y	T	K	R	L		G	T	E	K	E	V	E	V	I	G		G	A	D	K	Y	H	S	V	C	R		L	C	Y	F	K	K	A	S	G	Q
-------		V	K				+	-	-	+	-		-	-																-	+	I
1mjhA0_Seq		V	K	.	.	.	I	A	E	D	E		G	V	D	.	.	.	.	.	.	.		.	.	.	.	.	.	I	I	I	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.
1mjhA0_SS		H	H	.	.	.	H	H	H	H	H		C	C	C	.	.	.	.	.	.	.		.	.	.	.	.	.	E	E	E	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.
CORE		2	0	.	.	.	5	8	0	0	0		0	5	0	.	.	.	.	.	.	.		.	.	.	.	.	.	2	9	6	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.

thymid_PSS

C

C

C

C

C

C

C

C

C

C

C

.

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

C

C

C

C

C

C

thymid_Seq

P

A

G

P

D

N

K

E

N

C

P

.

V

P

G

K

P

G

E

A

V

A

A

R

K

L

F

A

P

Q

Q

I

L

Q

C

S

P

A

N

-------

-

G

-

-

-

K

-

N

-

-

-

-

-

-

-

-

+

-

-

-

+

K

-

-

-

P

-

-

+

+

+

-

1mjhA0_Seq

.

M

G

S

H

G

K

T

N

L

K

E

I

L

L

G

S

V

T

E

N

V

I

K

K

S

N

K

P

V

L

V

V

K

.

R

K

N

S

1mjhA0_SS

.

E

E

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

C

.

C

C

C

C

CORE

.

5

2

1

0

0

0

0

0

0

0

0

0

0

1

0

0

3

2

0

0

7

1

0

0

4

0

0

0

5

2

2

3

0

.

0

0

0

0