Alignment of thymidine_kinase with 1gdtB-

Alignment of thymidine_kinase with 1gdtB-

PSSM Score Key
-10																			10

Bad																			Good

thymid_PSS	Predicted Secondary Structure for your Sequence
thymid_Seq	Your Sequence
1gdtB-_Seq	Library Sequence
1gdtB-_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

thymid_PSS		C	C	C	C	C	C	C	C	C	C		C	C	C	C	C	C	C	C	E	E		E	E	E	E	E	E	E	C	C	C		C	H	H	H	H	H	H	H	H	H		H	H	H	H	H	C	C	C	E	E
thymid_Seq		M	S	C	I	N	L	P	T	V	L		P	G	S	P	S	K	T	R	G	Q		I	Q	V	I	L	G	P	M	F	S		G	K	S	T	E	L	M	R	R	V		R	R	F	Q	I	A	Q	Y	K	C
-------		M																						-	-	+	-	-	-	-		-	+			-			-	-	-			V		R		-	+	-	A	-
1gdtB-_Seq		M	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		R	L	F	G	Y	A	R	V	S	T		S	Q	Q	S	L	D	I	Q	.	V		R	A	L	K	D	A	G	.	.	.
1gdtB-_SS		C	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		C	E	E	E	E	C	C	C	C	C		C	H	H	H	H	H	H	H	.	H		H	H	H	H	H	C	C	.	.	.
CORE		0	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		0	1	2	3	2	2	0	0	0	0		0	0	0	0	1	0	0	0	.	1		0	0	3	0	0	1	1	.	.	.

thymid_PSS

E

E

E

E

E

C

C

C

C

C

C

C

C

C

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

E

E

E

E

E

E

.

.

.

.

thymid_Seq

L

V

I

K

Y

A

K

D

T

R

Y

S

S

S

F

C

T

H

D

R

N

T

M

E

A

L

P

A

C

L

L

R

D

V

A

Q

E

A

L

G

V

A

V

I

G

I

.

.

.

.

-------

K

R

-

-

-

D

+

-

+

-

-

-

-

-

-

L

-

-

+

-

-

-

-

V

I

-

+

1gdtB-_Seq

.

.

.

.

.

V

K

A

N

R

.

.

.

.

.

I

F

T

D

K

A

S

G

S

S

S

D

R

K

G

L

D

L

L

R

M

K

V

E

E

G

D

V

I

L

V

K

K

L

D

1gdtB-_SS

.

.

.

.

.

C

C

C

C

C

.

.

.

.

.

E

E

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

E

C

C

H

H

CORE

.

.

.

.

.

0

0

0

0

0

.

.

.

.

.

2

2

1

0

0

0

0

0

0

0

0

0

0

0

1

4

0

0

4

0

0

0

3

0

0

0

0

0

7

3

6

0

0

5

0

thymid_PSS

.

.

.

.

E

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

.

.

E

E

E

C

C

C

C

C

.

H

H

H

C

C

C

C

C

H

H

H

H

thymid_Seq

.

.

.

.

D

E

G

Q

F

F

P

D

I

M

E

F

C

E

A

M

A

N

A

G

K

T

V

.

.

I

V

A

A

L

D

G

T

.

F

Q

R

K

P

F

G

A

I

L

N

L

-------

D

-

-

D

+

+

-

-

+

-

+

-

G

-

+

+

I

-

+

-

+

K

-

+

-

I

L

-

-

1gdtB-_Seq

R

L

G

R

D

T

A

.

.

.

.

D

M

I

Q

L

I

K

E

F

D

A

Q

G

V

S

I

R

F

I

D

D

G

I

S

T

D

G

E

M

G

K

M

V

V

T

I

L

S

A

1gdtB-_SS

H

C

C

C

C

H

H

.

.

.

.

H

H

H

H

H

H

H

H

H

H

H

H

C

E

E

E

E

E

C

C

C

C

E

E

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

CORE

0

9

1

0

0

0

0

.

.

.

.

0

3

1

0

3

8

0

0

5

0

0

0

0

3

1

8

0

5

1

0

0

0

2

0

5

0

0

0

0

0

0

0

1

3

0

0

6

0

0

thymid_PSS		H	H	H	H	H	H	H	H	H	C		C	H	H	H	H	H	H	C	C	C		C	C	E	E	E	E	E	C	C	C		C	E	E	E	E	E	C	C	C	C		C	C	H	H	H	H	H	H	H	C
thymid_Seq		V	P	L	A	E	S	V	V	K	L		T	A	V	C	M	E	C	F	R	E		A	A	Y	T	K	R	L	G	T	E		K	E	V	E	V	I	G	G	A	D		K	Y	H	S	V	C	R	L	C	Y
-------		V	-	-	A	E	-	-	-	-	L		-	-			+	E	-			E		A																										-	-	+	-	-	+
1gdtB-_Seq		V	A	Q	A	E	R	Q	R	I	L		E	R	T	.	N	E	G	R	Q	E		A	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	M	A	K	G	V	V
1gdtB-_SS		H	H	H	H	H	H	H	H	H	H		H	H	H	.	H	H	H	H	H	H		H	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	H	H	H	C	C	C
CORE		0	0	0	0	0	0	0	0	0	0		0	0	0	.	0	0	0	0	0	0		0	.	.	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	.	.	0	0	0	0	0	0

thymid_PSS

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

C

C

.

C

C

C

C

thymid_Seq

F

K

K

A

S

G

Q

P

A

G

P

D

N

K

E

N

C

P

V

P

G

K

P

G

E

A

V

A

A

R

K

L

F

A

P

Q

Q

I

L

Q

C

.

S

P

A

N

-------

F

-

-

+

-

-

D

-

N

-

-

-

+

G

+

-

-

+

+

-

-

-

-

A

-

+

-

+

+

-

-

-

N

1gdtB-_Seq

F

G

R

K

R

K

I

D

.

.

R

D

A

V

L

N

M

W

Q

Q

G

L

G

A

S

H

I

S

K

T

M

N

I

A

R

S

T

V

Y

K

V

I

N

E

S

N

1gdtB-_SS

C

C

C

C

C

C

C

C

.

.

H

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

C

C

CORE

0

0

0

0

0

0

3

0

.

.

0

0

0

6

1

0

1

0

0

0

0

1

0

1

0

0

5

2

0

0

1

0

4

0

0

0

0

5

0

0

2

3

0

0

0

0