Alignment of thymidine_kinase with 1dekA0

Alignment of thymidine_kinase with 1dekA0

PSSM Score Key
-10																			10

Bad																			Good

thymid_PSS	Predicted Secondary Structure for your Sequence
thymid_Seq	Your Sequence
1dekA0_Seq	Library Sequence
1dekA0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

thymid_PSS

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

E

E

E

E

E

E

E

E

E

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

thymid_Seq

M

S

C

I

N

L

P

T

V

L

P

G

S

P

S

K

T

R

G

Q

I

Q

V

I

L

G

P

M

F

S

G

K

S

T

E

L

M

R

R

V

R

R

F

Q

I

A

Q

Y

K

C

-------

M

+

-

+

+

+

G

+

-

S

G

K

+

T

-

+

-

+

-

+

+

+

+

Y

-

1dekA0_Seq

M

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

K

L

I

F

L

S

G

V

K

R

S

G

K

D

T

T

A

D

F

I

M

S

N

Y

S

A

V

K

Y

Q

.

1dekA0_SS

C

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

E

E

E

E

E

E

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

E

E

E

C

C

.

CORE

0

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

0

2

2

2

2

0

0

0

0

0

0

0

0

0

0

2

1

0

0

3

1

0

0

0

0

2

0

0

0

0

.

thymid_PSS

E

E

E

E

E

C

C

C

.

.

.

.

.

.

.

.

.

.

.

.

C

C

C

C

C

C

E

E

E

E

C

C

C

C

C

C

C

C

C

.

.

C

C

C

H

H

H

H

H

H

thymid_Seq

L

V

I

K

Y

A

K

D

.

.

.

.

.

.

.

.

.

.

.

.

T

R

Y

S

S

S

F

C

T

H

D

R

N

T

M

E

A

L

P

.

.

A

C

L

L

R

D

V

A

Q

-------

-

-

-

-

-

K

D

T

-

Y

-

+

-

-

+

-

-

+

-

-

-

-

+

V

1dekA0_Seq

.

L

A

G

P

I

K

D

A

L

A

Y

A

W

G

V

F

A

A

N

T

D

Y

P

L

T

R

K

E

F

E

G

I

D

Y

D

R

E

T

N

L

N

L

T

K

L

E

V

I

T

1dekA0_SS

.

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

H

H

H

H

H

C

C

C

C

C

C

C

C

E

C

C

C

C

H

H

H

H

H

H

CORE

.

2

0

0

1

2

0

0

6

7

0

0

3

1

0

0

1

0

0

0

0

0

0

0

1

0

0

0

0

2

0

0

0

0

0

0

0

0

0

0

2

0

3

0

0

0

0

3

2

0

thymid_PSS		H	H	C	C	E	E	E	.	.	.		.	.	.	.	.	.	.	.	.	E		E	E	E	C	C	C	.	.	.	.		C	.	.	C	C	H	H	H	H	H		.	.	.	.	.	.	.	.	.	.
thymid_Seq		E	A	L	G	V	A	V	.	.	.		.	.	.	.	.	.	.	.	.	I		G	I	D	E	G	Q	.	.	.	.		F	.	.	F	P	D	I	M	E	F		.	.	.	.	.	.	.	.	.	.
-------		-		-	-		-															+		-	-	D	E	G	+						F			F	-		I		+
1dekA0_Seq		I	M	E	Q	A	F	C	Y	L	N		G	K	S	P	I	K	G	V	F	V		F	D	D	E	G	K	E	S	V	N		F	V	A	F	N	K	I	T	D	V		I	N	N	I	E	D	Q	W	S	V
1dekA0_SS		H	H	H	H	H	H	H	H	H	H		H	H	C	C	C	C	C	C	C	E		E	E	C	C	C	C	E	E	E	C		H	H	H	H	H	H	H	H	H	H		H	H	H	C	C	C	C	C	E	H
CORE		3	6	0	0	7	6	1	0	6	0		0	0	0	0	4	0	0	4	0	1		0	0	0	0	0	0	0	0	4	0		0	0	2	1	0	0	6	0	0	1		4	0	0	0	0	0	0	1	0	1

thymid_PSS

H

H

H

H

H

H

C

C

C

E

E

E

E

E

C

C

C

C

C

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

H

C

C

thymid_Seq

C

E

A

M

A

N

A

G

K

T

V

I

V

A

A

L

D

G

T

F

Q

R

K

P

F

G

A

I

L

N

L

V

P

L

A

E

S

V

V

K

L

T

A

V

C

M

E

C

F

R

-------

-

+

-

M

-

+

G

-

-

-

I

V

-

-

D

-

+

-

-

K

+

F

+

+

+

-

-

+

-

-

+

+

-

-

-

1dekA0_Seq

R

R

L

M

Q

A

L

G

T

D

L

I

V

N

N

F

D

R

M

Y

W

V

K

L

F

.

.

.

.

.

A

L

D

Y

L

D

K

F

N

S

G

Y

D

Y

Y

I

V

P

D

T

1dekA0_SS

H

H

H

H

H

H

H

H

H

C

H

H

H

H

H

H

C

C

H

H

H

H

H

H

H

.

.

.

.

.

H

H

H

H

H

H

H

H

C

C

C

C

C

E

E

E

E

C

C

C

CORE

0

0

5

1

0

4

9

0

0

0

5

5

0

0

0

4

0

0

0

1

1

1

0

1

2

.

.

.

.

.

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

2

2

0

0

1

thymid_PSS

C

C

C

E

.

.

.

E

E

E

E

C

C

C

C

E

E

E

E

E

C

C

C

C

C

C

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

thymid_Seq

E

A

A

Y

.

.

.

T

K

R

L

G

T

E

K

E

V

E

V

I

G

G

A

D

K

Y

H

S

V

C

R

L

C

Y

F

K

K

A

S

G

Q

P

A

G

P

D

N

K

E

N

-------

-

-

+

-

R

-

-

-

-

-

-

+

V

-

-

+

K

-

-

-

-

-

-

A

G

-

-

-

+

1dekA0_Seq

R

Q

D

H

E

M

D

A

A

R

A

M

G

A

T

V

I

H

V

V

R

P

G

Q

K

.

.

.

.

.

.

.

.

.

S

N

D

T

H

I

T

E

A

G

L

P

I

R

D

G

1dekA0_SS

C

C

H

H

H

H

H

H

H

H

H

H

C

C

E

E

E

E

E

E

C

C

C

C

C

.

.

.

.

.

.

.

.

.

C

C

C

C

C

H

H

H

C

C

C

C

C

C

C

C

CORE

0

0

0

0

0

1

0

0

2

0

0

1

0

2

0

1

3

0

2

0

0

0

0

0

0

.

.

.

.

.

.

.

.

.

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

thymid_PSS

C

C

C

C

C

C

C

C

H

H

H

.

H

H

H

H

H

C

C

C

H

H

H

H

C

C

C

C

C

C

thymid_Seq

C

P

V

P

G

K

P

G

E

A

V

.

A

A

R

K

L

F

A

P

Q

Q

I

L

Q

C

S

P

A

N

-------

-

-

V

-

+

-

-

G

-

-

-

K

+

-

-

-

-

L

1dekA0_Seq

D

L

V

I

T

N

D

G

S

L

E

E

L

F

S

K

I

K

N

T

L

K

V

L

.

.

.

.

.

.

1dekA0_SS

C

E

E

E

E

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

.

.

.

.

.

.

CORE

0

1

0

2

0

0

0

0

0

0

0

0

2

0

0

0

1

0

0

1

2

0

0

1

.

.

.

.

.

.