Alignment of thymidine_kinase with 1ajz-0

Alignment of thymidine_kinase with 1ajz-0

PSSM Score Key
-10																			10

Bad																			Good

thymid_PSS	Predicted Secondary Structure for your Sequence
thymid_Seq	Your Sequence
1ajz-0_Seq	Library Sequence
1ajz-0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

thymid_PSS

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

E

E

E

E

E

E

E

E

E

C

C

C

C

H

H

.

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

thymid_Seq

M

S

C

I

N

L

P

T

V

L

P

G

S

P

S

K

T

R

G

Q

I

Q

V

I

L

G

P

M

F

S

G

K

S

.

T

E

L

M

R

R

V

R

R

F

Q

I

A

Q

Y

K

-------

M

-

+

-

-

-

T

-

L

-

+

S

+

-

+

-

G

-

-

V

-

-

-

-

-

+

-

G

-

+

L

-

-

V

-

+

-

-

-

1ajz-0_Seq

M

K

L

F

A

Q

G

T

S

L

D

L

S

H

P

H

V

M

G

I

L

N

V

T

P

D

S

F

S

D

G

G

T

H

N

S

L

I

D

A

V

K

H

A

N

L

.

.

.

.

1ajz-0_SS

C

E

E

E

E

C

C

E

E

E

E

C

C

C

C

E

E

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

.

.

.

.

CORE

0

0

4

0

1

0

0

0

0

2

0

2

0

0

1

0

2

2

2

0

7

0

6

0

0

0

0

2

0

0

0

0

0

0

0

0

1

0

0

5

0

0

0

4

0

0

.

.

.

.

thymid_PSS

E

E

E

E

E

E

C

C

C

C

C

C

C

C

C

E

E

E

E

C

C

C

C

C

C

.

.

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

E

E

E

E

.

.

.

thymid_Seq

C

L

V

I

K

Y

A

K

D

T

R

Y

S

S

S

F

C

T

H

D

R

N

T

M

E

.

.

A

L

P

A

C

L

L

R

D

V

A

Q

E

A

L

G

V

A

V

I

.

.

.

-------

-

-

-

+

-

-

-

-

-

-

-

-

A

-

+

-

-

+

-

-

-

V

-

I

1ajz-0_Seq

.

.

.

.

.

.

.

.

M

I

N

A

G

A

T

I

I

D

V

G

G

E

S

T

R

P

G

A

A

E

V

S

V

E

E

E

L

Q

R

V

I

P

V

V

E

A

I

A

Q

R

1ajz-0_SS

.

.

.

.

.

.

.

.

H

H

H

H

C

C

C

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

CORE

.

.

.

.

.

.

.

.

2

1

0

0

1

2

0

3

4

0

9

2

2

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

6

1

0

6

7

0

0

5

2

0

0

thymid_PSS		.	.	.	.	.	E	E	E	C	C		C	C	C	C	H	H	H	.	H	H		H	H	H	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	H	H	H	C	C	C	E	E
thymid_Seq		.	.	.	.	.	G	I	D	E	G		Q	F	F	P	D	I	M	.	E	F		C	E	A	.	.	.	.	.	.	.		.	.	.	.	.	.	.	.	.	.		.	.	M	A	N	A	G	K	T	V
-------							-	+	D	-	-		+			P		+	+		E	-		+	+	+																							A	-	-	G	+	+	V
1ajz-0_Seq		F	E	V	W	I	S	V	D	T	S		K	.	.	P	E	V	I	R	E	S		A	K	V	G	A	H	I	I	N	D		I	R	S	L	S	E	P	G	A	L		E	A	A	A	E	T	G	L	P	V
1ajz-0_SS		C	C	C	E	E	E	E	E	C	C		C	.	.	H	H	H	H	H	H	H		H	H	H	C	C	C	E	E	C	C		C	C	C	C	C	C	C	C	H	H		H	H	H	H	H	H	C	C	C	E
CORE		0	0	2	1	5	2	7	0	1	0		0	.	.	0	0	3	5	0	0	4		1	0	1	2	6	0	4	6	0	0		0	0	1	9	0	0	0	0	4	4		0	1	9	2	0	1	0	2	1	8

thymid_PSS

E

E

E

C

C

C

C

C

H

H

.

.

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

H

C

C

C

C

C

E

E

E

E

E

C

thymid_Seq

I

V

A

A

L

D

G

T

F

Q

.

.

R

K

P

F

G

A

I

L

N

L

V

P

L

A

E

S

V

V

K

L

T

A

V

C

M

E

C

F

R

E

A

A

Y

T

K

R

L

G

-------

+

+

-

-

-

-

G

+

-

+

+

-

-

-

-

-

-

-

+

-

-

-

-

-

A

C

-

+

-

-

-

1ajz-0_Seq

C

L

M

H

M

Q

G

N

P

K

T

M

Q

E

A

P

K

Y

D

D

V

F

A

E

V

N

R

Y

F

I

E

Q

I

A

R

C

E

Q

A

G

.

.

.

.

.

.

.

.

I

A

1ajz-0_SS

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

.

.

.

.

.

.

.

.

C

C

CORE

2

5

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

1

0

0

0

3

0

0

6

0

0

1

0

.

.

.

.

.

.

.

.

7

0

thymid_PSS

C

C

C

E

E

E

E

.

.

E

C

.

C

C

C

C

.

.

.

C

H

H

H

H

H

H

.

.

.

H

C

C

C

C

.

.

.

.

.

C

C

C

C

C

C

.

.

.

.

.

thymid_Seq

T

E

K

E

V

E

V

.

.

I

G

.

G

A

D

K

.

.

.

Y

H

S

V

C

R

L

.

.

.

C

Y

F

K

K

.

.

.

.

.

A

S

G

Q

P

A

.

.

.

.

.

-------

E

K

-

+

-

-

+

G

G

-

Y

-

-

R

L

+

-

F

S

-

-

-

1ajz-0_Seq

K

E

K

L

L

L

D

P

G

F

G

F

G

K

N

L

S

H

N

Y

S

L

L

A

R

L

A

E

F

H

H

F

N

L

P

L

L

V

G

M

S

R

K

S

M

I

G

Q

L

L

1ajz-0_SS

H

H

H

E

E

E

E

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

E

E

E

C

C

C

C

C

H

H

H

H

H

H

H

CORE

0

0

0

5

3

2

0

1

0

2

0

0

0

0

0

0

0

0

0

0

0

1

2

0

0

4

0

0

1

0

0

1

0

2

1

2

2

4

0

2

0

0

0

0

1

0

0

0

0

0

thymid_PSS

.

.

C

C

C

C

C

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

C

C

thymid_Seq

.

.

G

P

D

N

K

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

E

N

C

P

V

P

G

K

P

G

E

A

V

A

A

R

K

L

F

A

P

Q

Q

I

L

Q

C

-------

G

P

-

-

-

-

V

-

-

-

-

+

-

A

+

R

-

+

-

A

-

-

-

-

1ajz-0_Seq

N

V

G

P

S

E

R

L

S

G

S

L

A

C

A

V

I

A

A

M

Q

G

A

H

I

I

R

V

H

D

V

K

E

T

V

E

A

M

R

V

V

E

A

T

L

S

A

K

E

N

1ajz-0_SS

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

CORE

0

0

0

0

0

0

0

0

0

0

0

0

0

1

2

0

0

6

2

0

0

0

5

0

4

3

0

1

0

0

2

0

0

1

0

0

0

1

0

0

0

0

0

0

0

0

0

0

0

0

thymid_PSS		C	C	C	C
thymid_Seq		S	P	A	N
-------		-	-	-	-
1ajz-0_Seq		K	R	Y	E
1ajz-0_SS		C	C	C	C
CORE		0	0	0	0