-This SVM was trained using LIBSVM-3.12, with the -b 1 option used to enable probability outputs.
-Features should be scaled before use using svm-scale (provided by LIBSVM-3.12) and the scaling parameters available at the SuSPect website.
-Prediction should be carried out using svm-predict -b 1
-Output will be a score from 0-1, which should be multiplied by 100 to give the SuSPect score.

The following features are included in SuSPect-FS:

4 - PPI degree from STRING
24 - Number of annotations for that position in the UniProt FT table
36 - PSSM score of wild-type
37 - PSSM score of variant
38 - Feature 36-Feature 37
42 - (Pfam HMM emission score for the wild-type amino acid) - (Pfam HMM emission score for the variant amino acid)
43 - Jensen-Shannon divergence
45 - Percentage sequence identity with the closest homologue to have the variant amino acid at that position
80 - Predicted relative solvent accessibility from NetSurfP