Found 257 pleiotropic proteins (16.0 %) and 1345 non-pleiotropic proteins (84.0 %).
1602 items found (page 31 of 33)
| Gene | UniProt | Protein Type | Disease |
|---|---|---|---|
| TRIM32 | Q13049 | pleiotropic | Limb-girdle muscular dystrophy 2H (LGMD2H) [MIM:254110] Bardet-Biedl syndrome 11 (BBS11) [MIM:209900] |
| TRIM37 | O94972 | non-pleiotropic | Mulibrey nanism (MUL) [MIM:253250] |
| TRIOBP | Q9H2D6 | non-pleiotropic | Deafness, autosomal recessive, 28 (DFNB28) [MIM:609823] |
| TRPA1 | O75762 | non-pleiotropic | Episodic pain syndrome, familial, 1 (FEPS1) [MIM:615040] |
| TRPC6 | Q9Y210 | non-pleiotropic | Focal segmental glomerulosclerosis 2 (FSGS2) [MIM:603965] |
| TRPM1 | Q7Z4N2 | non-pleiotropic | Night blindness, congenital stationary, 1C (CSNB1C) [MIM:613216] |
| TRPM4 | Q8TD43 | non-pleiotropic | Progressive familial heart block 1B (PFHB1B) [MIM:604559] |
| TRPM6 | Q9BX84 | non-pleiotropic | Hypomagnesemia 1 (HOMG1) [MIM:602014] |
| TRPV3 | Q8NET8 | non-pleiotropic | Olmsted syndrome (OLMS) [MIM:614594] |
| TRPV4 | Q9HBA0 | pleiotropic | Brachyolmia 3 (BRAC3) [MIM:113500] Metatropic dysplasia (MTD) [MIM:156530] Spondylometaphyseal dysplasia Kozlowski type (SMDK) [MIM:184252] Parastremmatic dwarfism (PSTD) [MIM:168400] Charcot-Marie-Tooth disease 2C (CMT2C) [MIM:606071] Distal spinal muscular atrophy, congenital non-progressive (DSMAC) [MIM:600175] Scapuloperoneal spinal muscular atrophy (SPSMA) [MIM:181405] Digital arthropathy-brachydactyly, familial (FDAB) [MIM:606835] |
| TSC2 | P49815 | pleiotropic | Tuberous sclerosis 2 (TSC2) [MIM:613254] Lymphangioleiomyomatosis (LAM) [MIM:606690] |
| TSEN2 | Q8NCE0 | non-pleiotropic | Pontocerebellar hypoplasia 2B (PCH2B) [MIM:612389] |
| TSEN34 | Q9BSV6 | non-pleiotropic | Pontocerebellar hypoplasia 2C (PCH2C) [MIM:612390] |
| TSFM | P43897 | non-pleiotropic | Combined oxidative phosphorylation deficiency 3 (COXPD3) [MIM:610505] |
| TSHR | P16473 | pleiotropic | Familial gestational hyperthyroidism (HTFG) [MIM:603373] Hyperthyroidism, non-autoimmune (HTNA) [MIM:609152] Hypothyroidism, congenital, non-goitrous, 1 (CHNG1) [MIM:275200] |
| TSPAN12 | O95859 | non-pleiotropic | Vitreoretinopathy, exudative 5 (EVR5) [MIM:613310] |
| TSPAN7 | P41732 | non-pleiotropic | Mental retardation, X-linked 58 (MRX58) [MIM:300210] |
| TTC21B | Q7Z4L5 | pleiotropic | Nephronophthisis 12 (NPHP12) [MIM:613820] Bardet-Biedl syndrome (BBS) [MIM:209900] Short-rib thoracic dysplasia 4 with or without polydactyly (SRTD4) [MIM:613819] Joubert syndrome 11 (JBTS11) [MIM:613820] |
| TTC37 | Q6PGP7 | non-pleiotropic | Trichohepatoenteric syndrome 1 (THES1) [MIM:222470] |
| TTC7A | Q9ULT0 | non-pleiotropic | Intestinal atresia, multiple (MINAT) [MIM:243150] |
| TTI2 | Q6NXR4 | non-pleiotropic | Mental retardation, autosomal recessive 39 (MRT39) [MIM:615541] |
| TTPA | P49638 | non-pleiotropic | Ataxia with isolated vitamin E deficiency (AVED) [MIM:277460] |
| TUBA1A | Q71U36 | non-pleiotropic | Lissencephaly 3 (LIS3) [MIM:611603] |
| TUBB1 | Q9H4B7 | non-pleiotropic | Macrothrombocytopenia, autosomal dominant, TUBB1-related (MAD-TUBB1) [MIM:613112] |
| TUBB2B | Q9BVA1 | non-pleiotropic | Polymicrogyria, symmetric or asymmetric (PMGYSA) [MIM:610031] |
| TUBB3 | Q13509 | pleiotropic | Congenital fibrosis of extraocular muscles 3A (CFEOM3A) [MIM:600638] Cortical dysplasia, complex, with other brain malformations 1 (CDCBM1) [MIM:614039] |
| TUBB4A | P04350 | pleiotropic | Dystonia 4, torsion, autosomal dominant (DYT4) [MIM:128101] Leukodystrophy, hypomyelinating, 6 (HLD) [MIM:612438] |
| TUBG1 | P23258 | non-pleiotropic | Cortical dysplasia, complex, with other brain malformations 4 (CDCBM4) [MIM:615412] |
| TUFM | P49411 | non-pleiotropic | Combined oxidative phosphorylation deficiency 4 (COXPD4) [MIM:610678] |
| TWIST1 | Q15672 | pleiotropic | Saethre-Chotzen syndrome (SCS) [MIM:101400] Craniosynostosis 1 (CRS1) [MIM:123100] |
| TYMP | P19971 | non-pleiotropic | Mitochondrial DNA depletion syndrome 1, MNGIE type (MTDPS1) [MIM:603041] |
| UBA1 | P22314 | non-pleiotropic | Spinal muscular atrophy X-linked 2 (SMAX2) [MIM:301830] |
| UBE2A | P49459 | non-pleiotropic | Mental retardation, X-linked, syndromic, Nascimento-type (MRXSN) [MIM:300860] |
| UBE3B | Q7Z3V4 | non-pleiotropic | Blepharophimosis-ptosis-intellectual disability syndrome (BPIDS) [MIM:615057] |
| UBIAD1 | Q9Y5Z9 | non-pleiotropic | Corneal dystrophy, Schnyder type (SCCD) [MIM:121800] |
| UBQLN2 | Q9UHD9 | non-pleiotropic | Amyotrophic lateral sclerosis 15, with or without frontotemporal dementia (ALS15) [MIM:300857] |
| UBR1 | Q8IWV7 | non-pleiotropic | Johanson-Blizzard syndrome (JBS) [MIM:243800] |
| UCP3 | P55916 | non-pleiotropic | Obesity (OBESITY) [MIM:601665] |
| UGT1A1 | P22309 | pleiotropic | Crigler-Najjar syndrome 1 (CN1) [MIM:218800] Crigler-Najjar syndrome 2 (CN2) [MIM:606785] Gilbert syndrome (GILBS) [MIM:143500] Transient familial neonatal hyperbilirubinemia (HBLRTFN) [MIM:237900] |
| UMPS | P11172 | non-pleiotropic | Orotic aciduria 1 (ORAC1) [MIM:258900] |
| UNG | P13051 | non-pleiotropic | Immunodeficiency with hyper-IgM 5 (HIGM5) [MIM:608106] |
| UPB1 | Q9UBR1 | non-pleiotropic | Beta-ureidopropionase deficiency (BUPD) [MIM:613161] |
| UPF3B | Q9BZI7 | non-pleiotropic | Mental retardation, X-linked, syndromic, 14 (MRXS14) [MIM:300676] |
| UQCRC2 | P22695 | non-pleiotropic | Mitochondrial complex III deficiency, nuclear 5 (MC3DN5) [MIM:615160] |
| UQCRQ | O14949 | non-pleiotropic | Mitochondrial complex III deficiency, nuclear 4 (MC3DN4) [MIM:615159] |
| UROC1 | Q96N76 | non-pleiotropic | Urocanase deficiency (UROD) [MIM:276880] |
| UROS | P10746 | non-pleiotropic | Congenital erythropoietic porphyria (CEP) [MIM:263700] |
| USH1G | Q495M9 | non-pleiotropic | Usher syndrome 1G (USH1G) [MIM:606943] |
| UVSSA | Q2YD98 | non-pleiotropic | UV-sensitive syndrome 3 (UVSS3) [MIM:614640] |
| VANGL1 | Q8TAA9 | pleiotropic | Sacral defect with anterior meningocele (SDAM) [MIM:600145] Neural tube defects (NTD) [MIM:182940] |