Found 257 pleiotropic proteins (16.0 %) and 1345 non-pleiotropic proteins (84.0 %).
1602 items found (page 27 of 33)
Gene | UniProt | Protein Type | Disease |
---|---|---|---|
SH2D1A | O60880 | non-pleiotropic | Lymphoproliferative syndrome, X-linked, 1 (XLP1) [MIM:308240] |
SH3BP2 | P78314 | non-pleiotropic | Cherubism (CRBM) [MIM:118400] |
SH3PXD2B | A1X283 | non-pleiotropic | Frank-Ter Haar syndrome (FTHS) [MIM:249420] |
SHOC2 | Q9UQ13 | non-pleiotropic | Noonan syndrome-like disorder with loose anagen hair (NSLH) [MIM:607721] |
SHOX | O15266 | pleiotropic | Leri-Weill dyschondrosteosis (LWD) [MIM:127300] Langer mesomelic dysplasia (LMD) [MIM:249700] |
SHROOM4 | Q9ULL8 | non-pleiotropic | Mental retardation, X-linked, syndromic, Stocco dos Santos type (SDSX) [MIM:300434] |
SI | P14410 | non-pleiotropic | Congenital sucrase-isomaltase deficiency (CSID) [MIM:222900] |
SIAE | Q9HAT2 | non-pleiotropic | Autoimmune disease 6 (AIS6) [MIM:613551] |
SIGMAR1 | Q99720 | non-pleiotropic | Amyotrophic lateral sclerosis 16, juvenile (ALS16) [MIM:614373] |
SIX5 | Q8N196 | non-pleiotropic | Branchiootorenal syndrome 2 (BOR2) [MIM:610896] |
SIX6 | O95475 | non-pleiotropic | Microphthalmia, isolated, with cataract, 2 (MCOPCT2) [MIM:212550] |
SKIV2L | Q15477 | non-pleiotropic | Trichohepatoenteric syndrome 2 (THES2) [MIM:614602] |
SLC10A2 | Q12908 | non-pleiotropic | Primary bile acid malabsorption (PBAM) [MIM:613291] |
SLC11A2 | P49281 | non-pleiotropic | Anemia, hypochromic microcytic, with iron overload 1 (AHMIO1) [MIM:206100] |
SLC12A1 | Q13621 | non-pleiotropic | Bartter syndrome 1 (BS1) [MIM:601678] |
SLC12A3 | P55017 | non-pleiotropic | Gitelman syndrome (GS) [MIM:263800] |
SLC16A2 | P36021 | non-pleiotropic | Monocarboxylate transporter 8 deficiency (MCT8 deficiency) [MIM:300523] |
SLC17A8 | Q8NDX2 | non-pleiotropic | Deafness, autosomal dominant, 25 (DFNA25) [MIM:605583] |
SLC19A2 | O60779 | non-pleiotropic | Thiamine-responsive megaloblastic anemia syndrome (TRMA) [MIM:249270] |
SLC19A3 | Q9BZV2 | non-pleiotropic | Thiamine metabolism dysfunction syndrome 2, biotin- or thiamine-responsive type (THMD2) [MIM:607483] |
SLC1A3 | P43003 | non-pleiotropic | Episodic ataxia 6 (EA6) [MIM:612656] |
SLC20A2 | Q08357 | non-pleiotropic | Basal ganglia calcification, idiopathic, 1 (IBGC1) [MIM:213600] |
SLC22A12 | Q96S37 | non-pleiotropic | Hypouricemia renal 1 (RHUC1) [MIM:220150] |
SLC22A18 | Q96BI1 | non-pleiotropic | Lung cancer (LNCR) [MIM:211980] |
SLC22A5 | O76082 | non-pleiotropic | Systemic primary carnitine deficiency (CDSP) [MIM:212140] |
SLC25A1 | P53007 | non-pleiotropic | Combined D-2- and L-2-hydroxyglutaric aciduria (D2L2AD) [MIM:615182] |
SLC25A12 | O75746 | non-pleiotropic | Global cerebral hypomyelination (GCHM) [MIM:612949] |
SLC25A15 | Q9Y619 | non-pleiotropic | Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH syndrome) [MIM:238970] |
SLC25A20 | O43772 | non-pleiotropic | Carnitine-acylcarnitine translocase deficiency (CACTD) [MIM:212138] |
SLC25A22 | Q9H936 | non-pleiotropic | Epileptic encephalopathy, early infantile, 3 (EIEE3) [MIM:609304] |
SLC25A3 | Q00325 | non-pleiotropic | Mitochondrial phosphate carrier deficiency (MPCD) [MIM:610773] |
SLC25A38 | Q96DW6 | non-pleiotropic | Anemia, sideroblastic, pyridoxine-refractory, autosomal recessive (PRARSA) [MIM:205950] |
SLC26A3 | P40879 | non-pleiotropic | Diarrhea 1, secretory chloride, congenital (DIAR1) [MIM:214700] |
SLC26A4 | O43511 | pleiotropic | Deafness, autosomal recessive, 4 (DFNB4) [MIM:600791] Pendred syndrome (PDS) [MIM:274600] |
SLC26A8 | Q96RN1 | non-pleiotropic | Spermatogenic failure 3 (SPGF3) [MIM:606766] |
SLC27A4 | Q6P1M0 | non-pleiotropic | Ichthyosis prematurity syndrome (IPS) [MIM:608649] |
SLC29A3 | Q9BZD2 | non-pleiotropic | Histiocytosis-lymphadenopathy plus syndrome (HLAS) [MIM:602782] |
SLC2A1 | P11166 | pleiotropic | GLUT1 deficiency syndrome 1 (GLUT1DS1) [MIM:606777] GLUT1 deficiency syndrome 2 (GLUT1DS2) [MIM:612126] Dystonia 9 (DYT9) [MIM:601042] Epilepsy, idiopathic generalized 12 (EIG12) [MIM:614847] |
SLC2A10 | O95528 | non-pleiotropic | Arterial tortuosity syndrome (ATS) [MIM:208050] |
SLC2A2 | P11168 | non-pleiotropic | Fanconi-Bickel syndrome (FBS) [MIM:227810] |
SLC2A4 | P14672 | non-pleiotropic | Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853] |
SLC30A2 | Q9BRI3 | non-pleiotropic | Zinc deficiency, transient neonatal (TNZD) [MIM:608118] |
SLC34A3 | Q8N130 | non-pleiotropic | Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) [MIM:241530] |
SLC35A2 | P78381 | non-pleiotropic | Congenital disorder of glycosylation 2M (CDG2M) [MIM:300896] |
SLC35C1 | Q96A29 | non-pleiotropic | Congenital disorder of glycosylation 2C (CDG2C) [MIM:266265] |
SLC39A4 | Q6P5W5 | non-pleiotropic | Acrodermatitis enteropathica, zinc-deficiency type (AEZ) [MIM:201100] |
SLC3A1 | Q07837 | non-pleiotropic | Cystinuria (CSNU) [MIM:220100] |
SLC40A1 | Q9NP59 | non-pleiotropic | Hemochromatosis 4 (HFE4) [MIM:606069] |
SLC46A1 | Q96NT5 | non-pleiotropic | Hereditary folate malabsorption (HFM) [MIM:229050] |
SLC4A1 | P02730 | pleiotropic | Spherocytosis 4 (SPH4) [MIM:612653] Renal tubular acidosis, distal, autosomal dominant (AD-dRTA) [MIM:179800] Renal tubular acidosis, distal, with hemolytic anemia (dRTA-HA) [MIM:611590] Renal tubular acidosis, distal, with normal red cell morphology (dRTA-NRC) [MIM:611590] |