Found 257 pleiotropic proteins (16.0 %) and 1345 non-pleiotropic proteins (84.0 %).
1602 items found (page 12 of 33)
| Gene | UniProt | Protein Type | Disease |
|---|---|---|---|
| GALNS | P34059 | non-pleiotropic | Mucopolysaccharidosis 4A (MPS4A) [MIM:253000] |
| GALNT12 | Q8IXK2 | non-pleiotropic | Colorectal cancer 1 (CRCS1) [MIM:608812] |
| GALT | P07902 | non-pleiotropic | Galactosemia (GALCT) [MIM:230400] |
| GAMT | Q14353 | non-pleiotropic | Cerebral creatine deficiency syndrome 2 (CCDS2) [MIM:612736] |
| GAN | Q9H2C0 | non-pleiotropic | Giant axonal neuropathy (GAN) [MIM:256850] |
| GARS | P41250 | pleiotropic | Charcot-Marie-Tooth disease 2D (CMT2D) [MIM:601472] Neuronopathy, distal hereditary motor, 5A (HMN5A) [MIM:600794] |
| GATA2 | P23769 | pleiotropic | Immunodeficiency 21 (IMD21) [MIM:614172] Myelodysplastic syndrome (MDS) [MIM:614286] Lymphedema, primary, with myelodysplasia (LMPM) [MIM:614038] |
| GATA3 | P23771 | non-pleiotropic | Hypoparathyroidism, sensorineural deafness, and renal disease (HDR) [MIM:146255] |
| GATA6 | Q92908 | pleiotropic | Atrioventricular septal defect 5 (AVSD5) [MIM:614474] Atrial septal defect 9 (ASD9) [MIM:614475] Tetralogy of Fallot (TOF) [MIM:187500] Pancreatic agenesis and congenital heart defects (PACHD) [MIM:600001] Conotruncal heart malformations (CTHM) [MIM:217095] |
| GATAD1 | Q8WUU5 | non-pleiotropic | Cardiomyopathy, dilated 2B (CMD2B) [MIM:614672] |
| GATM | P50440 | non-pleiotropic | Cerebral creatine deficiency syndrome 3 (CCDS3) [MIM:612718] |
| GBA2 | Q9HCG7 | non-pleiotropic | Spastic paraplegia 46, autosomal recessive (SPG46) [MIM:614409] |
| GCDH | Q92947 | non-pleiotropic | Glutaric aciduria 1 (GA1) [MIM:231670] |
| GCH1 | P30793 | pleiotropic | Dystonia 5 (DYT5) [MIM:128230] GTP cyclohydrolase 1 deficiency (GCH1D) [MIM:233910] |
| GCK | P35557 | pleiotropic | Maturity-onset diabetes of the young 2 (MODY2) [MIM:125851] Familial hyperinsulinemic hypoglycemia 3 (HHF3) [MIM:602485] |
| GCM2 | O75603 | non-pleiotropic | Hypoparathyroidism, familial isolated (FIH) [MIM:146200] |
| GDF1 | P27539 | pleiotropic | Tetralogy of Fallot (TOF) [MIM:187500] Conotruncal heart malformations (CTHM) [MIM:217095] Transposition of the great arteries dextro-looped 3 (DTGA3) [MIM:613854] |
| GDF2 | Q9UK05 | non-pleiotropic | Telangiectasia, hereditary hemorrhagic, 5 (HHT5) [MIM:615506] |
| GDF3 | Q9NR23 | pleiotropic | Microphthalmia, isolated, 7 (MCOP7) [MIM:613704] Klippel-Feil syndrome 3, autosomal dominant (KFS3) [MIM:613702] Microphthalmia, isolated, with coloboma, 6 (MCOPCB6) [MIM:613703] |
| GDF5 | P43026 | pleiotropic | Acromesomelic chondrodysplasia, Grebe type (AMDG) [MIM:200700] Brachydactyly A2 (BDA2) [MIM:112600] Du Pan syndrome (DPS) [MIM:228900] Multiple synostoses syndrome 2 (SYNS2) [MIM:610017] Symphalangism, proximal 1B (SYM1B) [MIM:615298] Brachydactyly C (BDC) [MIM:113100] Brachydactyly A1, C (BDA1C) [MIM:615072] |
| GDF6 | Q6KF10 | pleiotropic | Klippel-Feil syndrome 1, autosomal dominant (KFS1) [MIM:118100] Leber congenital amaurosis 17 (LCA17) [MIM:615360] Microphthalmia, isolated, 4 (MCOP4) [MIM:613094] |
| GDI1 | P31150 | non-pleiotropic | Mental retardation, X-linked 41 (MRX41) [MIM:300849] |
| GFAP | P14136 | non-pleiotropic | Alexander disease (ALEXD) [MIM:203450] |
| GFER | P55789 | non-pleiotropic | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss and developmental delay (MPMCHD) [MIM:613076] |
| GFM1 | Q96RP9 | non-pleiotropic | Combined oxidative phosphorylation deficiency 1 (COXPD1) [MIM:609060] |
| GFPT1 | Q06210 | non-pleiotropic | Myasthenic syndrome, congenital, with tubular aggregates, 1 (CMSTA1) [MIM:610542] |
| GHRHR | Q02643 | non-pleiotropic | Growth hormone deficiency, isolated, 1B (IGHD1B) [MIM:612781] |
| GHSR | Q92847 | non-pleiotropic | Short stature, idiopathic, autosomal (ISSA) [MIM:604271] |
| GIF | P27352 | non-pleiotropic | Hereditary intrinsic factor deficiency (IFD) [MIM:261000] |
| GIGYF2 | Q6Y7W6 | non-pleiotropic | Parkinson disease 11 (PARK11) [MIM:607688] |
| GIPC3 | Q8TF64 | non-pleiotropic | Deafness, autosomal recessive, 15 (DFNB15) [MIM:601869] |
| GJA1 | P17302 | pleiotropic | Oculodentodigital dysplasia (ODDD) [MIM:164200] Atrioventricular septal defect 3 (AVSD3) [MIM:600309] Hypoplastic left heart syndrome 1 (HLHS1) [MIM:241550] Syndactyly 3 (SDTY3) [MIM:186100] Hallermann-Streiff syndrome (HSS) [MIM:234100] Craniometaphyseal dysplasia, autosomal recessive (CMDR) [MIM:218400] |
| GJA3 | Q9Y6H8 | non-pleiotropic | Cataract 14, multiple types (CTRCT14) [MIM:601885] |
| GJA5 | P36382 | pleiotropic | Atrial standstill 1 (ATRST1) [MIM:108770] Atrial fibrillation, familial, 11 (ATFB11) [MIM:614049] |
| GJA8 | P48165 | non-pleiotropic | Cataract 1, multiple types (CTRCT1) [MIM:116200] |
| GJB2 | P29033 | pleiotropic | Deafness, autosomal recessive, 1A (DFNB1A) [MIM:220290] Deafness, autosomal dominant, 3A (DFNA3A) [MIM:601544] Keratoderma, palmoplantar, with deafness (PPKDFN) [MIM:148350] Vohwinkel syndrome (VS) [MIM:124500] Keratitis-ichthyosis-deafness syndrome (KID syndrome) [MIM:148210] Ichthyosis hystrix-like with deafness syndrome (HID syndrome) [MIM:602540] Bart-Pumphrey syndrome (BPS) [MIM:149200] |
| GJB3 | O75712 | pleiotropic | Erythrokeratodermia variabilis (EKV) [MIM:133200] Deafness, autosomal dominant, 2B (DFNA2B) [MIM:612644] |
| GJB4 | Q9NTQ9 | non-pleiotropic | Erythrokeratodermia variabilis (EKV) [MIM:133200] |
| GJB6 | O95452 | pleiotropic | Deafness, autosomal dominant, 3B (DFNA3B) [MIM:612643] Ectodermal dysplasia 2, Clouston type (ECTD2) [MIM:129500] |
| GJC2 | Q5T442 | pleiotropic | Leukodystrophy, hypomyelinating, 2 (HLD2) [MIM:608804] Spastic paraplegia 44, autosomal recessive (SPG44) [MIM:613206] Lymphedema, hereditary, 1C (LMPH1C) [MIM:613480] |
| GK | P32189 | non-pleiotropic | Glycerol kinase deficiency (GKD) [MIM:307030] |
| GLB1 | P16278 | pleiotropic | GM1-gangliosidosis 1 (GM1G1) [MIM:230500] GM1-gangliosidosis 3 (GM1G3) [MIM:230650] GM1-gangliosidosis 2 (GM1G2) [MIM:230600] Mucopolysaccharidosis 4B (MPS4B) [MIM:253010] |
| GLDC | P23378 | non-pleiotropic | Non-ketotic hyperglycinemia (NKH) [MIM:605899] |
| GLI2 | P10070 | non-pleiotropic | Holoprosencephaly 9 (HPE9) [MIM:610829] |
| GLI3 | P10071 | pleiotropic | Polydactyly, postaxial A1 (PAPA1) [MIM:174200] Polydactyly, postaxial B (PAPB) [MIM:174200] Greig cephalo-poly-syndactyly syndrome (GCPS) [MIM:175700] |
| GLRA1 | P23415 | non-pleiotropic | Hyperekplexia 1 (HKPX1) [MIM:149400] |
| GLRB | P48167 | non-pleiotropic | Hyperekplexia 2 (HKPX2) [MIM:614619] |
| GLUD1 | P00367 | non-pleiotropic | Familial hyperinsulinemic hypoglycemia 6 (HHF6) [MIM:606762] |
| GLUL | P15104 | non-pleiotropic | Congenital systemic glutamine deficiency (CSGD) [MIM:610015] |
| GLYCTK | Q8IVS8 | non-pleiotropic | D-glyceric aciduria (D-GA) [MIM:220120] |