HHsearch 1.5 NAME c6hmsB_ FAM FILE c6hmsB_ COM /bmm/www/servers/phyre2/HH/hhmake -i c6hmsB_.a3m DATE Sat Feb 2 09:01:01 2019 LENG 1101 match states, 1101 columns in multiple alignment FILT 31 out of 35 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.2 EVD 0.3274 -7.2234 SEQ >ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSCSSCSCCCBCSHHHHHHHHSCCSSTHHHHHHHHHHSCTTHHHHHHHHHHHHCCSSCCCSHHHHHHHHH HHHHHHHHTTCSSTTTTSCCEEEEEECTTTSCCEEEEEECCSTTTTTCTTHHHHHHHHHHHHHHHHTCCCCCCCSHHHHHHHHHHHHHHSSSSCCSSCCC HHHHHHHHHHCCSEECCSCCSCCBCSSCSCSSCCCSBCCTHHHHHHTTTTSSTHHHHHHHHHHHTCSSTHHHHHHSCCCCCCCSHHHHHHHHHHHCCCCH HHHHHHHHSCCCCCCCEEECCCCSSSCSSSCBBCSHHHHHSCCCCTTCSSBCCCSSSCCCCCCBCSSCCCCEEEETTSCEEECCSTTHHHHHGGGEEEEE ECCEEECCSCSTTSSCCCCCCCCSCHHHHHHHHHHHHTTTTCCCCCSSSCCCHHHHHHHHHHHTCCHHHHHHHHHCTTTCCCCHHHHHHHHHTTCCCCCS TTCCCGGGSCHHHHHHHHHHHHHHCEEEEEESSSCEEEEEEECCTTTTSSTHHHHHTTTCCCEEETTEEEBCTTHHHHHHTTTTTTTSCCCCCSSSCHHH HHHHHCSCCCCCSCCCCCCCCCCSCBGGGSCCCCCSCSBCCCCCSSSTTSCCHHHHHHHTCCCCEEECCEECTTTTCBCSSSBCSSSCCBCEECEECTTT CCEECHHHHHHHTTBCSSSCSBCBSCEEECCCHHHHHHHHTTTTCCCCCSCCCBCSCCCSSSCCCCCSHHHHHHHHHTCCCCTTSSCCCEEEEECCSCBC TTTTTCCHHHHHTTTCCBCTTSSBCCCTTCCBCCCTTEEEEEHHHHHHHHHHHHHHHHHHHHTSCCCCSSCCCSHHHHTTCEEEEECTTCSEEEEEEEEE EESSSCEECCHHHHCHHHHHSSCCEEEEEEHHHHHHTCCSTTSCSSCCCSSCCCCEEECCCCCCCCCTTHHHHHHTTCCSHHHHHHSCSCCCCCCSSHHH HHHHHHHHCTTCSTTHHHHHHHHHHHHCCTHHHHHHSCCCCCSSSCCCCCCCCCSCSSSSSSCCCCCCCCCCSHHHHHHHTSCSHHHHHHHHHHHHHTTC C >sa_dssp EEDDEDCCDEBCEDBEECCECADEBBDCBDCDBDDBDBDCBDDBACBBDDCBDBEDBBEDBDDCCEEDDDDDABCCBBDCBCDCDCDEBEEDCECBCDAB DBBBBBCCCBCBACBDCABDCBCDCEBDEDEEBCBBABBBBCBBECBCCDCBABBCCCBBCBBDCCEBDEBDCDEEBBCBBBDBACDBCEEECECEEEBD DEDBDDCBECCBABBCBEDCCEDEADCDEBDECEDCCBBBBBABBCBCACDEBBEDBCDCBEECECEEBDECDEBCEEEEECEECDACECDCEDDCEDDD EDCEDBCECDABBBACBBBCBBDECDCDDCBBCACBCBBCCCECEECCCCBCBCBDCBEBCBCEBECBCABBACCDEECBDCBBEEEDBCECDEDCDCBB BBBBCCBBBBCCCEEBEDCBCCBBCBCBBBCCCBDBBCEDCEBEBDCDDECEEEBBDDBBEDAECCDEECCECBDCABECDBDBCDBBABDDCBEBCCBB CCBCBCCDBEBECBCDBBDCCCEDCECDECEECEBEBBCDBCACBEDBCEBDDACDDBBBBCCCEEDDBCBDCDDABBBCCCBCDCEEDADCDEEDCABB ABCECBECEBDBBACACCCBBABDECBEDBCDCEBECCAABBACEDCCECCABCEBBEECDDBECCBCCCDADEEECEBCDCDBDECECEBDBBABADEE EDDCCCDEADEDECCADEBEDEBDBCBEBEBEBCEDCDCBBEDBDCEEBEDBDACDDBDBCCCCCBDCBCBBABBCBEBDABDBABBBBBCBBCCCCCCD BEDBEBDBEDBDECDBCDBDEEEDBECDDCCCDBBBBBBBCBCDCBEDBCDAADABADBBDECCECECDCEAEEBDCBCCBBBABBBCCBBBABBBBBAA CCEDCCCCBBDDBBCEDCCEDECCCBABBBBABBCCBCBDCBCCEEEACEDCBBDBBCBDEEEEECDCEBBDBAEDDDECEDBCDEBEECACCACCEBCE CACCBBDCBDCCEDEACCBBBCCCEECCEECEEDEEDDECEBEDDEDECEDEEDEEECCEDDBEDCEDEEDCDDADECAEECEEBDDECCECBDDDDEEE E >ss_pred CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC HHHHHHHHHCCCEEECCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH HHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHH HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC CCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCEEEECCEEEEECCHHHHHHHHHCCCCCHHHHCCCHHHHH HHHHHCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCCCCCCEEECCCCCCCCCEEEECCCC CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCCCCCHHHHHHHHHHCCCEEECCCCEECCCCCCCCCEEE HHHHCCCHHHHHHCCCCCCCCCCCCCCHHHEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEECCCHHHHHHHHHEE EECCCEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHH C >ss_conf 9027999999999999999999999874999987742565340788876540810178999999756084489999999985152566000788986557 8888776301333001021010542467778851699996077366771589999999999999738744688888998999999978865204224898 8999999836983783787764020346776447663116889898868874538899998861886606899983146665444332213454457113 5688875287788821320043102235213457889987510010351544317985027765047778768926987777399899999775033533 3456777566665268842783212799999877410100100011011121000000000135553110000133445689999999999980897587 7320243189999999999986222123444444543344112047712489999972563473099179606125788874234641011001001578 8875369136125761244333787433343178998157134445855123687504688127999854677888623000373448844112203333 8555655333456556325678776544672399999999986386675653200000134767645788787665182041277143002278400022 7782999899984286445489867882245773036078502489999999978999999980897135899876633302200066025546533102 2104423207203442016788428899999998863256638777887243434420136867869799999751799789999999898799999999 9898998763355799999863022567754444203520203568820037877505100887413236679999999871984785202578755651 9 >Consensus xeexxxYfxxLxxxxxxxxeiAxxARxxGxDpxxxVEIplAxDmAdRVExligixgvAxrIrelexxxsrEeaalxixxeixegkxgxxxxxxxxxexAV RtalAilTEGVVaAPlEGIaxVxikkNdxxDGteYlavyyAGPIRSAGGTAqALSVLvaDyvRxxlGlxxYkpxxdEIeRYvEEVxlYxxevxxlQYxPx xxEirxixxnxPVxIdGexTexxEVshRdlxRVeTNxiRGGmxLVlxEGixxKApKixkxvxklxxxgWxwLxxlxxxxxxxxxxxxxxexxxxxixpxx KylxdlIaGRsxxGGFRLRYGRsRntGfAtxGxhPAtMxlldxFiAvGTQlKxErPGKaxxVvPVdsIegPtVkLxnGdVxrIddxxxAxxxrxxVeeIL xlGdiLvxyGdFlENNhxLxPsxyxxEWWxqexxxaxxxxxxxxxxpxxdxxxxxxxxxxxyxxxxxxxxxxxxxxxxxxxpxxxeAixxsxxxxvPLHP xytYxWhdIsxeelxxLxxxlxxxxxxexxxxxxxxxxxxxxlxxxxxxxvKxiLExLxvxHxxxxxxivixxxxaxxllxxLGxxxxxxxxxxxxxxix xvnxlsxxxirxraptrIGxRmGRPEKaxxRkMkPxvhxLFPIGxaGGxxRxixxAxxxxxxxxveixxrxCpxCgxxtxxxxCpxCGxxTxxxxxCxxC xxxxxxxxxexxxxxcxxcxxxxxxxxxxxixlxxxxxxAlxxlgxxxxxxlKGVkGlxSxxkixEPLEKGILRAkxxvxvFKDGTiRfDxtDxPlTHfr pxEIgvsvekLreLGYxxDixGxpLxxxdQivELkxQDIvlpxxaaeylxxvaxFIDdLLeKxYglxpfYnvxxxeDLIGhLViGlAPHTSagvvgRIIG FtxaxvgYAHPyfHAAKRRNCDGDEDxvmLLlDxLlNFSrxyLPdxrGGxMDAPLVltxxidPxeYPleFYeatxxxxxpxevxxxyxtlxtMxdKxxaQ lxLaxxIRAVDexdVAerVixsHFlPDlxGNLRaFsrQxfRCxkCxakYRRxPLsGxCxkCGgxixlTxKYLxxsxxlaxeYxqrlxllxxxIxslFexx x >c6hmsB_ PKEMEEYFEMLQREIDKAYEIAKKARAQGKDPSLDVEIPQATDMAGRVESLVGPPGVAKRIRELVKEYGKEIAALKIVDEIIEGKFGDLGSREKYAEQAV RTALAILTEGIVSAPIEGIANVKIKRNTWADNSEYLALYYAGPIRSSGGTAQALSVLVGDYVRRKLGLDRFKPSEKHIERMVEEVDLYHRAVTRLQYHPS PEEVRLAMRNIPIEITGEATDDVEVSHRDVPGVETNQLRGGAILVLAEGVLQKAKKLVKYIDKMGIEGWEWLKEFVEAKEDMGFYYSLYQKFKEEIAPSD KYAKEVIGGRSKPGGFRLRYGRSRASGFATWGINPATMILVDEFLAIGTQLKTERPGKGAVVTPVTTIEGPIVKLKDGSVLRVDDYNLALKVREDVEEIL YLGDAVIAFGDFVENNQTLLPANYCEEWWILEFVKALKEIYEVHLEPFTENEEESIEEASDYLEIDPEFLKEMLRDPLRVKPPVELAIHFSEVLGIPLHP YYTLYWNSVEPKDVEKLWRLLKNYAEIEWSNFRGIKFAKKIVISQEKLGDSKRTLELLGLPHTVRDGNVIVDYPWAAALLTPLGNLNWEFMAKPLYATID IINENNEIKLRDRGISWIGARMGRPEKAKERKMKPPVQVLFPIGLAGGSSRDIKKAAEEGKVAEVEIAFFKCPKCGHVGPEHLCPNCGTRKELLWVCPRC NAEYPESQAEGYNYTCPKCNVKLRPYAKRKIRPSELLNRAMENVKVYGVDKLKGVMGMTSGWKMPEPLEKGLLRAKNDVYVFKDGTIRFDATDAPITHFR PREIGVSVEKLRELGYTHDFEGKPLVSEDQIVELKPQDIILSKEAGRYLLKVAKFVDDLLEKFYGLPRFYNAEKMEDLIGHLVIGLAPHTSAGIVGRIIG FVDALVGYAHPYFHAAKRRNCDGDEDAVMLLLDALLNFSRYYLPEKRGGKMDAPLVITTRLDPRYYPLEFYEATYELKSPKELVGVIERVEDMEEKVRRQ LEVAKRIRAVDEHGVAEKILNSHLIPDLRGNLRSFTRQEFRCVKCNTKFRRPPLNGKCPVCGGKIVLTEKYLGTAKMLVTEYNQRICLTERDIDSLFENV F >UniRef50_B9ZC02(4-1469:1481) DNA polymerase II, large subunit DP2 n=1 Tax=Natrialba magadii ATCC 43099 RepID=B9ZC02_NATMA E=0 s/c=1.00 id=45% cov=97% --EDERYFEQLESQLEEAFDVAERAKERGGDPEPDVEIPTARDMADRVENILGIDGVAERVRELEGEMSREEAALELAEDFAEGRVGDYETKAGKVEGAV RTAVALLTEGVVAAPIEGIDRVEILTND--DGTEFVNVYYAGPIRSAGGTAQALSVLVADYTRALVGIEQYEARQEEVERYAEEISLYDKE-TGLQYCPK DKEAKFIAKHLPIMLDGEATGDEEVSgFRDLERVDTNSARGGMCLVLGEGIALKAPKIQRYTRNLDEIDWPWLQDLIDgnyaadasdgddtadaAGSDDG SNEADTDENaendgddtdgdeteadessdeaavtdetdtsdsepvgPPRAEPSKKFLRDLIAGRpvfthpSSPGGFRLRYGRARNHGFATGGIHPATMHL VDDFLATGTQIKTERPGKAHGIIPVDSIDGPTVKLANGDVRRIDDPEEAKEIRNGVEKILDTGEYLVNYGEFVENNHPLAPASYVYEWWIQDMATAGADV QALEDDPRIDLEF----------------------------PDPAEALEWATEYDAPLHPQYTYLWHDISVESFCTLADAVAEGWVEAEPREGAGTGAND DTLVLECTESVQEALETLILEHRQRPDENRIEIDDWRPFARTLGceprqavadgaaldsdvgdadsdqasdsnsnsnsdsnpnaahdntlpiELERTWDD DDLSerartwghedeadgaNAIEAVNEVAPFEVRERAPTRIGNRMGRPEKSERRDLSPPVHTLFPIGEAGGAQRNVADAAKHAEtmsdtpgIVEIQIGRQ QCPSCGTETFKNRCPDCETRTEPDYRCPDCDQSLEPDD--SGRVECGRCEIEGTCVEPREIDINDEFRSALESVGERenAFEILKGVKGLTSQNKIPEPI EKGILRAKHDVSAFKDGTVRYDMTDLPVTSVRANELDIDVGQLQALGYEEDIHGDPLTHEDQLVELNVQDIVLSDGAAEHMMQTADFIDDLLEQYYGLEP FYEIDDRQELVGELVFGMAPHTSAATVGRVIGFTSAAVGYAHPYFHAAKRRNcfhpeteivyregesrsiydkqqlesddglppeerpqrdsirtfvedr lenpeqddfgteyqeldddvwvlsytgvccpkrvttvskhpapdhllsittesgrklrvtpdhtmlrfdedssdrlsqeywkaetvsaqelspgdelptp spvgertvddflfgpvkeindfppavtgwdvisdieiiesdtdyvyclevessntlsangiitgqCDGDEDCVMLLLDGLLNFSKSFLPDKRGGKMDAPL VMSSRIDPSEiddeahnmdivsqYPREFYLATREQADPEEVdiqigedtlgtdgeytgfehthdttdiamgpdLSAYKTLGSMMDKMDAQLELSRKLAAV DETDVAERVIEYHFLPDLIGNLRAFSRQETRCLDCGEKFRRMPLTGDCRECGGRVNLTvhqgsvNKYMQTAIQVAEEYDcrdytkQRLEVLEKSLESIFE N-- >UniRef50_D1JFA5(7-1075:1087) DNA polymerase II, large subunit n=1 Tax=uncultured archaeon RepID=D1JFA5_9ARCH E=0 s/c=1.30 id=46% cov=91% ------YHSTLKEKLDTELNIARAARKKGLDPAPTSEIKITKDLAERVEALIGVKGLGARIKELEQaGNSREELALKIGYDFVENKFGEY-RRIEIVELA VRTAVAILTEGVVAAPIEGISRVESDRND--DGSEYIKVFYSGPIRSAGGTAQVLSVLAADYIRRRMGFAAYQPRENEIGRYVLEVSVYER-ISGLQYKP TDDEIKEIVRGCPICIDGDATEDMEVgGFKDLQRVATNKIRGGMVLVLIEGIAMKATKIKRHVDRLGLEGWDFLAKLVKSKGEKKKKK------------ ---FLGDLIAGRpvfgrpSAKGSFSLRYGRSRNTGLETVGLNPYTMSLL-GFVAAGTQIKPELPGKAGCVVPVDSIDAATVKLKDGSLVRLDSAAAVTKL RDEVAEIVDVGEILIDYGDFLETGHRLMPGAYSHEWWLREL------------------EAKSKEEAAKWC---------------LKPPNQAEAIELAS RFAVPLHPAYTYLWADITEEDNAYLADSICK---------KGTSEENTLFIHSDDRGRIKAILEDLLVLHHIENGSLAIEKPDA--LLRCLG-ITGDLRR D----------ESTRVKTRNKAPTRIGVRMGRPEKSKERRMTPAPHSIFPVGEYGGKSRLLKEALKK-KVIEVEIGMRRCNECGNEFISSSC-------- ---ICDKCGSSNFKTPGLMQDA---RSRLKTGSRAKKSIDLWNYYHATIKKLGEsPNKQNVKCVQGLISKHKVAEHLGKGILRAKHGVFVFKDGTIRYDF TNLPLTHFKPKEIGLSLEKAKELGYSHDTFGKELERDVQIVELKQQDIVISLDAASYLLKVSQFLDSLLSKFYGLSPYYGASNKEDLLGELVLGLAPHTS AGILGRIIGFTKASACYAHPFFHAAKRRNCDGDEDSVLLLLDALINFSLFFLPEKRGGKMDAPLVLIPFINPKevdkearnvsiarEYPLEFYEAACSEK LPKEVdietastrieepkdvygflythettdiaagplNSLYKSLGTMMEKLDAQLKLARIIRAVDAPEVAEAVIENHFLRDIKGNLRAFGSQRMRCSKCN AKYRRIPLSGKCTRCGSKILPTvhiasvKKYLDVSMRMAKEYHlsdytrQRLELLQKDVNTLFPD-- >UniRef50_Q74N29(3-1230:1243) DNA polymerase II large subunit n=1 Tax=Nanoarchaeum equitans RepID=DP2L_NANEQ E=0 s/c=1.13 id=47% cov=98% ------YYDILAKELEKLYEIAEKARAQGYDPKDIVEIPLANNMGERVAHLISaiheqldVKKTAELILELEKQYGflDWRVGLKLIDYALEGKLIPYDD ILKRIDLGVRLALGYITMGVVSAPLEGLVELRIKKR--KDGKPYLALYYAGPIRGAGGTAAAVSVLFADYARKKAGLYEYDPTKEEIERYKIEIDSYHNK VARLQYKPSDEEIEFLVKHIPVEINGDPTSDKEVpSYKNLERVETNRIRGGMCLVIAEGIAQKAKKIYGKItewgKEFGLEHWEFLGEYLKLQKEIQAKL AaesggeiegkeikrkitlfLDEIKKEEItvkypTPAGKYLQEITAGRPifslpmAIGGFRLRYGRSFATGFATSGIHPATMFLTYGFLAIGTQMRGERP KKSTIVTPVTSLHPPIVKLKDGTVKKVHSVVEAIKIANDVEEILFLGDILTAFGDWLNEKANLVPSPYVEEWWIQEFDRAAMKKTDYKIEfdvmkPRKLF KIEGLENLSQYLGIPKDRLEEIIRKPFSRKPTIDEAITISEKLGIPLHPEYTPFWVHITKEELIKLIEELRK-----------AKIQNNKIYFHESQKEL KAILEKLFIEHFREGEYFYINESMTKSLLYQLDNLNLEKAKKEFDNAIdalDLVNRLSPIEIRDVAGVYVGFRAGRPEKAKMREMTGRPHGLFPVGEEGG KMRNVIEAYNKGYV-KAEFALYYCNHCKRYTIYRKCEVCGNKTKEVYVCKEIINRLKTSlfkqykdwkkveeeiashlWAEAVTHSKNNC-REPKRYSLI KLNIKHYVDRAVQKLKLFNIPKLvKGVRGTSNKDHIVERLEKAFLRSVSDVYVNKDGTIRYDGTQIPLTHFRPKDlIGVTIEKLKELGYTHDIYGNPLER EDQILQLKPQDIILPYgilvksrlnknkivrtDAAEAFKKVANFVDEELKRLYNLEPYYNIEKAEDLIGKIVFGIAPHTSAAVVGRIIGFTPIQGIIAHP IWHAGQRRNCDGDETAVMLGLDALINFSREYLPDKRGARtMDAPLVLTLKLELKAvddevhdmdivynYPLEFYYETLKGSPAKDVkkqcgiltlgdflk eediskipigfthptksirlgnkVSLYKRLKTMQQKTEWQLKLAERIRAVDENIVAEIVIEKHFMPDIKGNLRGFSSQVFRCTKCDTTYDRVPLSGKCPK CGGNIVFTvhegtiKKYLPTSLYLARKYkikkftKQSLFLLDRRIKQIF---- >UniRef50_B1L744(2-1090:1115) DNA polymerase II, large subunit DP2 n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L744_KORCO E=0 s/c=1.26 id=48% cov=92% -----DYFDTLRKGMDELLSVARRARSLGLDPSNDIEISLANELHERIAALFGIPELGERVKYWLDATGSKlETAFRVIGEIVPGYYLKI-SYERRAELA LRVGMAIITDATVSAPIEGISKVEVKKQ----GGTYLSVYYNGPIRTAGGTEGAISVLMADYIRQRLGIDRYRPTQEEIERYVEEVSLYKR-IAHLQYNS EPNEVRIAVSNLPVEITGPPTEKEEVsSFRNLPRVETNRVRGGAVLVINDCIIQKAKKLKKIIDQIKKIGfddscWGWIEGKKEEESEEEAGGC------ PVIEPSYKYLKDAVMGRpvlshpSRIGGFRLRYGRARNTGLASIGMNPATMYLLDSFIAVGTQVRIERPGKSAVVMPVDSIEGPTVRLRDGSVIRVDDPD EAMRIMDQVEEIIHLGDVLIGYGEFLENNHPLLPSAWVEEWWE----------------------------------------ALVRRKGLRAVRGFEDA LRASRELDVPLHPRFTYYWEHITSEELLKLAGAIRNSERAE----------------IDLNEDIKRILELLGVPHRVQNGKIVLDEEDWKALSY-IASKL PESLELPRYATIKVLNQYLDVKVMPKGPTKIGMRVGRPEKAKPRKMKPPVNLLFPVGNLKGSSRSLDLAYEKGSV-NVEVALRLCRKCGSRTTLFRCPNC GSPTYKISFCPICG-----KQVNGKCQDHPN--AEPVPYRSVKLNIREEVDRALRKLGESPgiLERVKGVKGLTSGSKIPEPIEKGILRAKHGLSVFKDG TVRFDAVNAVLTHFKPEEIGVSVEKLRELGYLEDVEGKYLEREDQLLELKVQDIIIPRAAAKYLLSIANYIDELLVKFYGLEPFYNLRDESDLIGQLVLT ISPHTFVANLARIIGFTNADVIFAHPFLHAAKRRNVDGDEDSIMLALDALINFSREFLPSSPGGREDAPLLLVTKVDPKyiddevynmevsELPPEFYEA TYKFEDPSKLKGIIETVgsrieagdlypkivgsietsrmdlgplqttyrklETMSDKMEAHFSLERKIRAVDEKDALSRALTSHFLRDIIGNLRKFGQQE FRCSECNAKYRRPPISGRCPRCGGNIVLTVhkgtvlKYLKPTLELIRRYGmegylsQRVKLIEGEISSLFK--- >UniRef50_A0RYM0(16-1099:1112) DNA polymerase II large subunit n=2 Tax=Thaumarchaeota RepID=DP2L_CENSY E=0 s/c=1.16 id=40% cov=92% PEEYRRYYSSLSGGTYDIFEKAASAKSNLADSSGMVEPKIAVDLSDRVAKM-HDLDIAGPLRELLATKGKELAALMLAKEIMDGKYLPEADIEKRIDSAV RVGLAVVTEGVTIAPLQGIADVITKKN--KDGSEYLSVSIAGPMRSAGGTESAVTMLIADYVRRQAGLAEYQADslDDETGRFIEELRIYEREVGSFQFH VLDEDIRAVISHLPVELDGVDTDPYEvVNHKGMSRIQTDRVRGGALRVLNDGLIGRSKKLLKRIELYGLDGWEWLAELKGAVQTGENKED---------- AAAKRMREVITGRSvlsmpnRLGGFRLRYGRACNTGYTSVGFHPAVAEILDHTIAVGTQVKIDIPGKGATVAFVDTIEAPTVRLAGGDVVKIRDVAHGIE LKGSIERILHLGDMLISFGDFLENNAQLVPSGYVEEIWKMDMEAAGA--------------------------------------AQGSPSSADEAVRIS RELGVPLHPRYLYYWDQISHEELAMLLSPLDKGDAISYP------------------AACKPVLEKLGVPHKAGPEGPVLEGDEARIFRELI--LDNPPG PDASAPVPELISRSSGITIRDKFSTSIGVRIGRPEKAAPRQMRPPTHCLFPVGGTGGPTNNlLKSAARPGFS--ADILSRRCPGCGEPSISIRCWACGER TAVERTCMQCGTDVDGEE-------CERCGRPGLAHSRVEFPLKKMLVSAQEKTGVRAHDPLKGVKELAHQDRIAEPLEKGLIRQSRSLTVFKDGTVRFD ATNSPMTHFKPSWIGTSAEKLRELGYETDVDGKKLEGPDQLVELRMQDIVIPLEGAKYLVSACGYIDAELDKLYGAPPFYKVPDLGGLIGHLVVGLAPHT SVGVAARIIGYTETHVCFGTPNWHSAKRRDADGDADSIILLMDALLNFSRHYLSDRIGGLMDAPLLIQPLVLPhesqsqahnievvKRLPPGFYEAAAAR KKASEVgcveivksrletagqfggyhfthgtsslttsrpRSAYSTLGSMLDKLDLQIRNANLIAAVDAAEIISNVISTHLVPDIMGNLRAYARQNFRCTA CGKSYRRIPLAQRCS-CGNGLIQTitrasvEKYLKLAKRLVNEYDVgayqrgRIHALSDEIELVF---- >UniRef50_Q6L1K9(8-1059:1080) DNA polymerase II large subunit n=2 Tax=Thermoplasmatales RepID=DP2L_PICTO E=0 s/c=1.32 id=45% cov=90% -----DYNERLRKETYECYEIAKKARAMGLDVSDEVEIPIANDMAERVEELIHISGIAGEIRELSKSMSREELSLHISKKVAS---LLKDNRVEALDKAV RVGLAILTEGILVAPLEGIKDVKINKND--DGTEYVSIVYSGPIRSAGGTAQALSVLIADIVRRELNIGSFSPTDDEIERYIEEVEAYNR-LKHLQYMPT PDEIRLVLKNSPVMIDgEGSEEEEVSGHRDMKRITTNRIRGGMCLVLCEGLIQKAKKVLKYTNVMHLNEWNILENIGKNKSDEKTEN-----------KS EKYLKDIIAGRpvfgypNRPGGFRLRYGRSRVSGLAAASINPVTMKILNDFIAIGSQIKVELPGKAAAITPCDSIDGPMVLTRSGDHIKVKSIEQAEKIK NDIERITDLGEILIAYGDFLENNRNLDLSPFTREWWEY-------------------------------------YLNDELSIYKSRDPDQFDAVNISRK YKMPMFPGYDYFWHDITMEELNLLINAIAN----------GIINDDSMML----DASVSEILIKLGIEFKKHNNKLILHEYYPLIVSCGFDLINEKIVKV SDERKNDVlgtVNALSGIEIKPRAPVRVGARLGRPEKAGDRKMKPKVHGLFPLMNYGGSTRSIINAARSGSIMDIELGARICRACGTETPFVRCPKCGMP TE-----------------------------DSDSEKKFKIDISKALDDAALRVStdIGTIKELKGVKKLMSRRSVIEPLEKAILRAKHGISINKDGTCR YDMSDIPITHFKYNEISLTRQRLMELGY----------SDSDINEIYPQDIIIPRDAASYLLNVSKFIDDLLVNYYGLGPYYMCNSEDDLIGHLVIGLAP HTSGGIVGRIIGFSDVNGCYAHPFFHAAKRRNCDGDEDSIMLLLDGLLNFSKKYLPSTTGGLMDAPLVLTLILDPEeidkealnvdtlqRYPLDFYIATE KNAPPASIENMmktmkvlikdgrytgisysfdtgdisygtrlsaYKTIGSMEEKIEKQLGLARILRSVDENDVAARVLSSHFLPDIYGNFRSFFTQEFRC TKCNAKYRRVPLSGRCLRCGsSNIILTihhgsiVKYLNETKKVMNEYKLPDYLV-FRINRLLEQI- >UniRef50_C7DGN4(2-1129:1147) DNA polymerase II, large subunit DP2 n=1 Tax=Candidatus Micrarchaeum acidiphilum ARMAN-2 RepID=C7DGN4_9EURY E=0 s/c=1.21 id=42% cov=94% --DSDEYFNEINASFNKAYEVAVKARSIGYDPKTTVEIRPAPDLASRVEGIIGIEGLADIIKAHADGKSRQELAFDIVRVIcTDGKF--EMEISSRLTLA VRIGLAILTEGILVAPTEGVQGVELHKN--PDGTSYISVMYAGPIRGAGGTSAALSVALADFARKLLGIGSYKAQKTEVERCIEEIQIYNSRAARLQYLP GDEDIRTILSNCPVCIDGMPTEQLEVAiHRNVARLDaagkqqmiTNRVRGGICLVSCEGIAQKAKSVLKYTKMAGLD-WSWLNKIIKVEKG-------TS KPGEDKKKTAVFLQELVAGRpvfaypNHHGSFRLRYGRSRLTGIAAKGFSPATMAILDDFIAVGTQLKVEKPGKGCIAMPVDSIEGPFVKLDSGQALRIN TYEDALRLRSSVKKILSVGDILVTYGDFKKTNTPLEPSSYVEEFWYEELKAAG------------------------------------FNGPMPSPASF KEALGYSKDYGVPMHPKYIYEYAEIQPPGLRALAESMAE-ADVEKSE-DSIFGLKSITLSGNRIEEVREALETLCVPHMDYGDRIKIDADDAQSLAFTLG ftengklHLSNDVLGKYAEAqdSLQMLSAISPVKIMRRS-TRIGGRMGRPEKAKSRLMKPAPNVLFPVGELGGKERSVSKAYSieskkfDSKGIYAEVAR FKCDKGGEYINSFYCRKHKSRATIERKCSVCGHLTNDKK-------CEKCGSKTNSSESKVLDLIEIVNAALSNLGIQAMPkNVKGVKSLMNGDMVPEPI EKGILRSLHDIHIFKDGTIRFDATDAPITHFYPNEIATPAERLKELGYKKDYMGNELKDDNQLVELMHQDVILNINCAEYFLKVSNFIDDLLVKYYGMQP FYNASKIQDLIGHYVITLSPHTSAGVLCRIIGFTKSNVGFAHPYVISARRRNCDGDEDTTMMLLDGLINFSRSYLPTTIGGTMDAPLILTINVMPEEvdd evhamevsesYGLDFYKSTLSYANPSEVEveivanrlgkksifsnlkfttpssdksinyapiqSSYTKLKTMQDKINKQFELMDILYSIDRSDTARRLIL SHFIPDLMGNLHSFSKQTFRCGNCNAKYRRVPLVGKCTKCGGKLLLTiskggiEKYLETATDLANRYNlenyikQRILLLRDEINAVF---- >UniRef50_Q8TUV3(6-1225:1240) DNA polymerase II large subunit n=1 Tax=Methanopyrus kandleri RepID=DP2L_METKA E=0 s/c=1.09 id=48% cov=98% -EELDRYRETLEEVSSRFVDVATKARQRREDPKPEPEVMLATSIGERVEGLLQVENVAdRLEELEEELGDREEATFRIVEEVIKGELKVKGDlpLHKRID YAVRIGLAVLTEAVVSAPLEGIAAVEIRERGTghrvVDESEppheepklvctecgkevdpencYLAVKYAGPIRAAGGTAAALSALLADYARQVAGLPRF NPDDfdhDLVGRYVEEVVTYLDKVGSFQYNPSEEEVELVAKNIPIEIDGEPTEEVEVqGHRDIPHL-PNQLRGGALLVICEGICQKAPKLIKRVEKYGID GWEFLEKLVNKGSD---DEEEGEEEKTKIKPNDKYMGELVAGRpllshpSAKGGFRLRYGRARNTGFAAVGVHPSLMYVTKGFIVIGTQLKVERPGKAAC VLPVTEIEPPVVKLRDGSVVRLDDPREAKELveKDEIEEILDLGEMLVAVGEFIENNHPLVPPAYCPEWWVKEVPDVvkviglRKNLPNDVFEKLKDVPL KRLVKEASRLSGNGNNLDGFLNGPVKVarsivelvrkeviprlsspeRMSVEEAIELSREYGVPFHPKYTFLWHDVKPKDVDELREALE-VAGSEWGNLR ---------VEFENDGEIKRILEDLLVPHRLEDDTIVVEEPWASALLAQLGYDpesgefreqdeDLDYLLDYLvirDETCRYVSKLAGFPIREKAPTRIG ARMGRPEKARERKMSPPPHVLFPIGIAGGNQRDIMKfhRGESEDTDRVEVCYRICPECDRLVPYRVCPFCGTET--VQYCNRCDEPADECDCEEPDPVV- RADIERNDDPYSSLPVRELVRRAEEEVG--TTDTLKGVKGMTSRLKMPEPLQKGILRAKRDLFVFKDGTLRFDCNDCPLTHVRLKEVGLTPFKARLLGFE RDINGDPVVSEDQVVELYPQDVVLPRKAAEWAVRVCQYLDDLLRKYYGLEPVYGVEKPEDLIGHLIVTLAPHTSCGVVGRVVGIADINCWYNHPIINAAR RRNCDGDEDAFMLLLDVLLNFSRLYLPDKRGGLMDAPLVLTAVVDPYEiddevwnmdvcgdYPLELYRKALEYADAGEAEELIERLEDRLDLPRglqfth dteaidlgptvtrysrlekmeekleEQLDLARRIRAVDESDVAKIVLDSHFLPDIKGNLRKFGRQKFRCSRCNAKFNVPPLSGKCPRCGGDVLLTiypat aTKYLEPAKRLVEEFGthdeewrtiaSEVELLEEEAKTLF---- >UniRef50_D2EGQ3(2-1130:1143) DNA polymerase II, large subunit DP2 n=1 Tax=Candidatus Parvarchaeum acidiphilum ARMAN-4 RepID=D2EGQ3_9EURY E=0 s/c=1.17 id=42% cov=94% --EIDSYHNKIIQEVKKQYEIIGKLKP--------INIPLASDVADKIEGLLSVlnqnlikSGLADFIREAEKKYGPNDWRVAIDSAIatADSKFIKFEN IHDAIEMGIRVGLAYITSAIVSAPLEGFVKLEFKKRM--DGQEYFACHFGGPIRGAGGTAAASVVVIADALRANFGYGKYDATEQEISRVKVEVTDYNDY EARLQYLPSSIELDFLLKNIPIEIDGDPTSDREVSaYKDLPRIKTNRIRSGMCLVLCEGFAQKSNKVNKLLKGFAknykiEDDFSFLVEYLKIKELSHAE KDSSEKENtssQKVLPNYRYIEELAAGRPvfsyplTSGGFRLRYGRSRTSGLAAASVNPATNKILMDFIATGSQLRVELPGKACAVTPCSTIDGPIVKLK NGSVRRINNAKLAEQVLNDIEEILYIGDILFNYGDFSEQGHLLMPSPFVSEWWDRIVESKGETAV---------NESKRLSNFVEYKD------------ -------------FSLKYGIPLHPKFLYFWSQISYKQLTELIESVHANAKIEYQNEIPGSAYKILILPLE--ESIKRTLELLAVEHYLKGNNIIIDN--A DAFLFTLGYNNVKFDALLLKigqnfFNLDLLSSISGLKIMDIAGTFIGGRLGRPEKAKMREMDTNPNVIFPIGESGGSSRNIIIAAQKPSVL-AEYGLFY CDKCKKDSIFTKCDVCGTETRRLRYCRVCGVKTTDSF---------HHGKPTSQKSKQSINLKEYLDRAFNRLEIRERPTViKGVKGVFNSNGDIEPLEK GILRAINGLNVNKDGTIRFDAIEVPITHFKPKEVGTSIEKLKELGYTEDIYGKELNNREQILQLKQQDIILPtygnsnENAAEVFSRVSNFIDELLMKYY SAEKMMNVKSREDLVGKLVVGLAPHTSSGTIGRIVGFSKTQGLFAHPFFHAAMRRNCDGDEAALMLLTDMLLNFDRGLLPDSRGARyMDSPLVISSKLDL EsidseaynldivdKYPLEFYEATLNYAKPSDVKimqvkdifkdpyrtiffthdtddinegvnvSSYKTLGTMLEKVSAQMALQEKIRAVDASDVAKIII DKHFIKDIKGNLRRFGTQEFRCVKCNERYRRAPLIGKCLKCGGNLVLTssegniKKYLSISLNIAQKYHisqylkDELHLLDVELDSIF---- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * P 1 * * * * * * * * * * * * 0 * * * * * * * 1 0 * * * * * * 1472 0 0 K 2 * * * 561 * * * * 1634 * * * * * * * * * * * 2 0 * * * * * * 2511 0 0 E 3 4180 * 2040 843 * 4569 * * * * * 3887 * * * * 4860 * * * 3 0 * * * * * * 2900 0 0 M 4 * * 3369 * * * * 3138 * 3024 1210 * * 4439 * 3965 * * * 3009 4 0 * * * * * * 2994 0 0 E 5 * * 2420 1645 * * 4623 * 2502 * 4614 * * 4655 2614 * 4947 * * * 5 0 * * * * * * 3037 0 0 E 6 3793 * 2423 2070 5165 * * * 3944 * * * * 3550 2318 3411 5033 * * * 6 0 * * * * * * 3154 0 0 Y 7 * * * * * * * * * * * * * * * * * * * 0 7 0 * * * * * * 3244 0 0 F 8 * * * * 739 * 3141 * * 4868 * 4821 * * 3609 * * * * 2878 8 0 * * * * * * 3244 0 0 E 9 5274 * 2231 1305 * * * * 3479 * * 2740 * * 5308 3444 * * * * 9 0 * * * * * * 3244 0 0 M 10 * * * 3245 * 4868 * 4308 3588 * 5099 3052 * 5332 2471 2868 2090 * * * 10 0 * * * * * * 3244 0 0 L 11 * * * * * * * 1892 * 453 * * * * * * * * * * 11 0 * * * * * * 3244 0 0 Q 12 4308 * * 1475 * * * 3570 4734 3224 * 3707 * 4039 3711 3514 * 4067 * * 12 0 * * * * * * 3244 0 0 R 13 2816 * 4082 3162 * 3557 * * 2166 * * 5682 * 4324 3079 2841 4263 * * * 13 0 * * * * * * 3244 0 0 E 14 * * 4179 1286 * 2201 5079 * 4734 * * 4286 * 3764 5005 4464 * 4359 * * 14 0 * * * * * * 3244 0 0 I 15 * * * * 3719 * * 4039 * 1338 4609 * * * * 4359 2701 2158 * * 15 0 * * * * * * 3244 0 0 D 16 5000 * 1989 2165 * 5030 * * 2918 * 5061 3929 * 4834 4017 4359 * * * 3479 16 0 * * * * * * 3244 0 0 K 17 5386 * 3219 2409 * * * * 1912 * * 5274 * 4039 2088 5061 3992 * * * 17 0 * * * * * * 3244 0 0 A 18 1376 3333 * 3919 4359 * * 3064 * 2313 * * * 4324 * * 5061 * * * 18 0 * * * * * * 3244 0 0 Y 19 * * * * 2192 * * 5005 * 3268 3411 * * * 5030 * * 4359 * 1081 19 0 * * * * * * 3244 0 0 E 20 4029 * 2423 828 * * * * 4668 * * 3988 * * 5619 3916 * * * * 20 0 * * * * * * 3244 0 0 I 21 * * * * * * * 991 4202 3479 * * * * 5079 * * 1629 * * 21 0 * * * * * * 3244 0 0 A 22 74 * * * * * * 4324 * * * * * * * * * * * * 22 0 * * * * * * 3244 0 0 K 23 4202 * * 2069 * 3634 * * 2722 * * 3315 * 5329 2167 4911 4359 4464 * * 23 0 * * * * * * 3244 0 0 K 24 3464 * * 3327 * 5274 * 5619 1303 * * * * 3993 2748 3569 4003 * * * 24 0 * * * * * * 3244 0 0 A 25 305 2827 * * * * * * * 4324 * * * * * * * * * * 25 0 * * * * * * 3244 0 0 R 26 * * * * * * * * 2049 * * * * * 399 * * * * * 26 0 * * * * * * 3244 0 0 A 27 2273 * * 3183 * 5079 * * 2843 * * 5298 4324 3856 5329 1536 * * * * 27 74 * 4324 * * * * 3244 0 0 Q 28 * * * * * * * 4379 2096 3129 4749 4146 * 2731 1739 5212 4927 * * * 28 0 * * * * * 0 3183 0 1000 G 29 * * * * * 263 * * * 3576 * 4992 * * 4285 * * * * * 29 0 * * * * * 0 3183 0 1000 K 30 4146 * * 3631 3186 2880 * * 3971 1768 4816 * * * * * * 4802 * 2409 30 0 * * * * * 0 3183 0 1000 D 31 * * 0 * * * * * * * * * * * * * * * * * 31 0 * * * * * 0 3183 0 1000 P 32 * * * * * * * * * * * * 476 * * 4146 * 2154 * * 32 0 * * * * * 0 3183 0 1000 S 33 4644 * * 2992 * * * * 2037 * * 5240 * 4965 4802 2116 2848 3882 * 4088 33 0 * * * * * 0 3183 0 1000 L 34 * * 2197 5251 4912 4146 * * * 3332 * 3309 1624 * * * 2823 * * * 34 0 * * * * * 0 3183 0 1000 D 35 * * 2403 1681 * * 4371 4162 4816 * 4146 4137 * * * * 3079 3935 * 4004 35 0 * * * * 0 * 3183 0 1000 V 36 * * * * * * * 2775 * * * * 3685 * * 4734 4834 507 * * 36 0 * * * * * * 3244 0 0 E 37 * * * 74 * * * * * * * 4324 * * * * * * * * 37 0 * * * * * * 3244 0 0 I 38 * * * * * * * 261 * * * * 4202 * * * * 3171 * * 38 0 * * * * * * 3244 0 0 P 39 * * * * * * * * 3444 * 4359 * 410 * 4464 4609 * * * 5619 39 0 * * * * * * 3244 0 0 Q 40 * * * * * * * 1876 * 1237 * * 4464 4039 * 5030 3764 3429 * * 40 0 * * * * * * 3244 0 0 A 41 55 * * * * * * * * * * * * * * * 4734 * * * 41 0 * * * * * * 3244 0 0 T 42 5682 * * * * * * * 1795 * * 2223 4464 * 3277 3090 3190 3283 * * 42 0 * * * * * * 3244 0 0 D 43 * * 262 4609 * * * * * * * 3712 * * * 4359 * * * * 43 0 * * * * * * 3244 0 0 M 44 * * * * * * * 4359 * 1329 991 * * * * * * 4324 * * 44 0 * * * * * * 3244 0 0 A 45 312 * * * * 3333 4609 * * * * * * * * 4202 * * * * 45 0 * * * * * * 3244 0 0 G 46 * * 1107 1338 * 3395 * * * * * * * * * 4464 * * * * 46 0 * * * * * * 3244 0 0 R 47 * * * * * * * * 4324 * * * * * 74 * * * * * 47 0 * * * * * * 3244 0 0 V 48 * * * * * * * 3010 * * * * * * * * * 191 * * 48 0 * * * * * * 3244 0 0 E 49 2778 * * 227 * * * * * * * * * * * * * * * * 49 0 * * * * * * 3244 0 0 S 50 2496 * * 4821 * 1519 4308 * 3202 * * 2413 * * * 4039 * 5030 * * 50 0 * * * * * * 3244 0 0 L 51 * * * * * * * 1820 * 664 4202 * * 5000 * * * * * * 51 81 * 4202 * * * * 3244 0 0 V 52 * * * * 4480 * * 2015 * 1716 4066 * * * * * * 1540 * * 52 0 * * * * 0 * 3168 0 1000 G 53 5079 * * * * 508 3479 * * * * * * 4359 * 2955 * * * * 53 75 4308 * 2807 222 * * 3244 1000 0 P 54 * * 4202 * * * * 1225 * * * * 1911 * * * * 2199 * 4868 54 74 4324 * 2807 222 * * 3244 1000 0 P 55 5061 * 2977 2697 * * * * 1898 4202 * 5274 2173 * * 3077 * * * * 55 0 * * * * * * 3244 0 0 G 56 * * 3575 4609 * 526 * * 4308 * * 3322 * 5061 * * * * * * 56 0 * * * * * * 3244 0 0 V 57 * * * * * * * 2419 * 2119 * * * * * * 4308 910 * * 57 0 * * * * * * 3244 0 0 A 58 207 * * * * 3670 * * * * * * * * * 4175 * * * * 58 72 4359 * 0 * * * 3244 1000 0 K 59 3280 * 2960 1419 * 3119 * * 3740 * * * 5030 4030 3148 * * * * * 59 0 * * * * * * 3244 0 0 R 60 * * * 4821 4324 * 5030 4464 3935 3333 5000 * 4202 4911 848 * * * * * 60 0 * * * * * * 3244 0 0 I 61 * * * 4359 * * * 456 * 4202 * * * * * * * 2573 * * 61 0 * * * * * * 3244 0 0 R 62 * * * 4359 * * * * 2411 4308 * * * * 542 * * 5274 * * 62 0 * * * * * * 3244 0 0 E 63 4464 * 3452 490 * * * * 5030 4359 * * * * * * * 5005 * 4609 63 0 * * * * * * 3244 0 0 L 64 4324 5030 * 4359 5132 * 4464 * * 453 5308 * * * * * * * 4609 * 64 0 * * * * * * 3244 0 0 V 65 4464 * 4114 912 * * * * * 3391 * * * * * 3866 * 2309 * * 65 42 5132 * 0 * * * 3244 1000 0 K 66 2777 * 2736 2875 * 2935 * 5298 1788 * * * * 3919 * 4164 * * * * 66 149 3352 * 329 2295 * * 3244 1664 0 E 67 4609 * 3642 1693 * 2771 * * 2787 4359 * * * 3749 4868 4821 4202 5000 * * 67 38 5274 * 0 * * * 3244 1000 0 Y 68 * * * * * 4359 5619 4834 3327 2321 1748 4734 * * 4093 * 4609 * * 2633 68 0 * * * * * * 3244 0 0 G 69 * * 4359 * * 1230 * * * * * * * * * 930 * * * * 69 75 4308 * 1000 1000 * * 3244 1000 0 K 70 * * 4308 * * * * * 1965 * * * 4324 * 731 4609 * * * * 70 0 * * * * * * 3244 0 0 E 71 * * * 298 * * * * 4609 * * 4324 * 4464 * * * * 4308 * 71 60 4609 * 0 * * * 3244 1000 0 I 72 * * 4324 636 * * * 3623 * 4202 * * 3052 * 4308 * * * * * 72 0 * * * * * * 3244 0 0 A 73 846 5005 * * * * * 5274 * 3080 * * * * * * 4609 2495 4324 * 73 0 * * * * * * 3244 0 0 A 74 633 5274 * * * 4308 * * * * * * * * 4324 2472 4359 * * * 74 0 * * * * * * 3244 0 0 L 75 * * * * 2152 * * * * 464 * * * * * * * 4324 * * 75 0 * * * * * * 3244 0 0 K 76 3672 * 4464 1409 * * 3908 * 2124 * 4202 * * 4068 3479 * * * * * 76 0 * * * * * * 3244 0 0 I 77 * * * * * * * 794 * 1936 4911 * * * * * * 2958 * * 77 0 * * * * * * 3244 0 0 V 78 1451 * 4324 * * 2619 * 3451 * * * * * * * 3866 * 1935 * * 78 0 * * * * * * 3244 0 0 D 79 2755 * 2500 2799 * 4609 * * 2250 * * * * * 2855 3741 5079 * * 4734 79 0 * * * * * * 3244 0 0 E 80 3570 * 1981 1199 * * * * 4821 * * * * 5005 4911 * * 4464 * 3613 80 0 * * * * * * 3244 0 0 I 81 4308 * * * 1795 * * 963 * * * * * * * * * 2752 * * 81 144 3392 * 599 1558 * * 3244 1455 0 I 82 1497 * * * * * * 2944 * 4308 4202 * * * * * 4464 1451 * * 82 49 * 4911 * * * * 3244 0 0 E 83 * * 2452 846 * 4827 * * 4321 * * 5275 4575 * * 3211 * * * * 83 62 * 4574 * * 0 * 3224 0 1000 G 84 * * 5273 * * 493 * * 3891 * * 3668 * 3917 * 4281 * * * * 84 0 * * * * * 0 3218 0 1000 K 85 5059 * * 2284 * * * 4646 1057 4985 * 5008 * * 3567 * 4182 * * 4571 85 0 * * * * * 0 3218 0 1000 F 86 * * * * 1060 * * * * 2926 * * * * * 4789 * 1971 * 3355 86 116 5059 4410 1000 1000 0 * 3218 1000 1000 G 87 * * 5035 * * 727 * 3248 3540 2860 * * * * * 4772 * * * * 87 39 * 5240 * * * 0 3193 0 1000 D 88 * * 1634 2496 * 4929 * * 2684 4712 * 3689 3161 * 4930 * * 4272 * * 88 109 * 3785 * * 0 * 3188 0 1494 L 89 * * * 3248 1886 5031 * 4526 3401 3949 * * 5020 * * * 3314 * * 1947 89 183 * 3069 * * 941 1061 3203 0 1418 G 90 2900 * 1440 2275 * 2348 * * * * 4263 * * * * 4557 * * * * 90 200 * 2951 * * 0 * 3137 0 1891 S 91 4655 * 2578 3599 * * * * * * * 2554 * * 4581 2079 1935 * * * 91 142 3420 * 1479 641 0 * 3249 1434 1546 R 92 * * 5150 * * * * 2322 1726 4359 * * 5298 * 1497 * * * * 4609 92 0 * * * * * * 3244 0 0 E 93 2903 * 5061 1181 * * 3341 4734 3958 3132 * * * * * 4464 * 4821 * * 93 0 * * * * * * 3244 0 0 K 94 5061 * 2519 2535 * 2675 * * 1722 * * * * * 4609 4464 5274 4286 * * 94 0 * * * * * * 3244 0 0 Y 95 1890 * * * * 5274 * 3278 2351 3567 * * * * 1942 * * * * 4039 95 52 4834 * 2322 322 * * 3244 1000 0 A 96 1705 * * * * * * 1642 * 2284 * * * * * * * 2577 * * 96 0 * * * * * * 3244 0 0 E 97 * * 1300 949 * * * * * * * * * 5030 * * 4464 * * * 97 0 * * * * * * 3244 0 0 Q 98 5005 5030 * * * 2675 3932 * 3404 2520 3672 * * 1911 * 4202 * * * 4359 98 0 * * * * * * 3244 0 0 A 99 210 * * * * 2884 * * * * * * * * * * * * * * 99 0 * * * * * * 3244 0 0 V 100 * * * * * * * 2263 * 3251 * * * * * * * 542 * * 100 0 * * * * * * 3244 0 0 R 101 * * * * * * * * * * * * * * 0 * * * * * 101 0 * * * * * * 3244 0 0 T 102 * * * * * * * 3410 * 4308 * * * * * * 774 1885 * * 102 0 * * * * * * 3244 0 0 A 103 741 * * * * 1700 * * * * * * * * * 3413 * * * * 103 0 * * * * * * 3244 0 0 L 104 5030 * * * * * * * * 778 2861 * * * * * * 2008 * * 104 0 * * * * * * 3244 0 0 A 105 75 * * * * 4308 * * * * * * * * * * * * * * 105 0 * * * * * * 3244 0 0 I 106 * * * * * * * 1324 * 1996 * * * * * * * 2002 * 3316 106 0 * * * * * * 3244 0 0 L 107 * * * * * * * 1646 * 736 * * * 5274 * * * 4202 * * 107 0 * * * * * * 3244 0 0 T 108 * * * * * * * * * * * * * * * * 0 * * * 108 0 * * * * * * 3244 0 0 E 109 * * 4609 220 * * * * * * 4308 * * * * 4324 * * * * 109 0 * * * * * * 3244 0 0 G 110 2840 * * * * 217 * * * * * * * * * * * * * * 110 0 * * * * * * 3244 0 0 I 111 * * * * * * * 1452 * * * * * * * * 4609 753 * * 111 0 * * * * * * 3244 0 0 V 112 * * * * * * * * * 3134 * * * * * * 4202 266 * * 112 0 * * * * * * 3244 0 0 S 113 864 * * * * * * 4202 * * * * * * * 1825 * 3134 * * 113 0 * * * * * * 3244 0 0 A 114 0 * * * * * * * * * * * * * * * * * * * 114 0 * * * * * * 3244 0 0 P 115 * * * * * * * * * * * * 0 * * * * * * * 115 0 * * * * * * 3244 0 0 I 116 * * * * * * * 1392 * 891 * * * * * * 3652 * * * 116 0 * * * * * * 3244 0 0 E 117 * * * 81 * * * * * * * * * 4202 * * * * * * 117 0 * * * * * * 3244 0 0 G 118 * * * * * 0 * * * * * * * * * * * * * * 118 0 * * * * * * 3244 0 0 I 119 * * * * 4324 * * 227 * 4308 * * * * * * * 4464 * * 119 0 * * * * 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