HHsearch 1.5 NAME c4h56M_ FAM FILE c4h56M_ COM /bmm/www/servers/phyre2/HH/hhmake -i c4h56M_.a3m DATE Wed Jan 9 14:50:40 2013 LENG 267 match states, 267 columns in multiple alignment FILT 20 out of 24 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 4.2 EVD 0.4133 -2.0668 SEQ >ss_dssp CCEEEEEEEEECTTTTCEEEEEEEEECTTCSSEEEEEEECCCCCCCCEEEECSSEEEEEEEEEEEEEEEEEESSSCCEEEEEESCCCCCCEEEEEEEEEE EEEEEEESSSCEEEEEEEEEEEEEEEEECCCSEEEEEEEECSSEEEEEEEECCCTTSCCTTCCCTTTBCCTTBSCSSSSCTGGGBCCTTTSCHHHHSCCC CCEEEEEEECTTCCEEEEEEEEEEEEEEEEEEEETTEEEEEECCCSCEEEEEEEEEEETTTTEEEEC >sa_dssp EDDCDECDCDBDCDEBDACBCADACCDEEDEBBCADBDBCCDBCBDCDCDDDCEDACACAABBADACBBBDBEEEDBCBEEACDDEEEDDEEEDEDDCED EDDEEDEDEDEEDECEDEDEDEEEDDEEECDDBDEDCECCEDDDABBBBDBCCCDEDCDCECEDEDCBBCABCCCBCDDDADCABCDDEEBCECACDCBC BEBCBCADACDEBCEACACACACACABBACADDDEECABBDCCEDEECDDCDACACBCBDDCBBECE >ss_pred CCEEEEECCCCCCCCEEEEEEEEEEECCCCCCEEEEEEEEEEECCCCEECCCCCCEEEECCCEEEEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEEEE EEEEEEECCCCCCCCCEEEEEEEEEEEEECCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHCCHHHCCCCC CCEEEEEECCCCCCEEEEEEEEEEEECCEEECCCEEEEEEEEECCCCCEEEEEEEEEECCCCEEEEC >ss_conf 9224520244554546889999986178877229999854431567255166640288727069988750357854799963264212326776677556 5117894488776500002455667887457416886147764035347864220687765555532103786420056765563786452423316878 6469999847887703899999873022362241179976210466510346889994554456549 >Consensus xxxxyxxxxxxxxxxxxxslxxxFIdDpxxdKxxxiixxxGxixsxxxxxxxxxxxxlxwPsxyxixxxxxxxNxxaxixxxaPkNxixtxxVxxTxgYx iGGxixvxxxxxxxsinaxxsxSxtISYxQpdYrTixxxxtxxkvxWxVxfxxxxxxYxrdSxxxxygnqlFmxsrxxxxxxxNfvxxxxlpxLxxxGFx PxxxavxsaxkxtxxSxfxVxyxRxxdxYxxxwxxxxwxGxnxkdxxxxxxxxxyxVDWknhxvkxx >c4h56M_ EAIKYTSSDTASHKGWKATLSGTFIEDPHSDKKTALLNLEGFIPSDKQIFGSKYYGKMKWPETYRINVKSADVNNNIKIANSIPKNTIDKKDVSNSIGYS IGGNISVEGKTAGAGINASYNVQNTISYEQPDFRTIQRKDDANLASWDIKFVETKDGYNIDSYHAIYGNQLFMKSRLYNNGDKNFTDDRDLSTLISGGFS PNMALALTAPKNAKESVIIVEYQRFDNDYILNWETTQWRGTNKLSSTSEYNEFMFKINWQDHKIEYY >UniRef50_Q99RL1(43-310:315) Gamma-hemolysin component C n=192 Tax=root RepID=HLGC_STAAM E=2e-58 s/c=0.85 id=26% cov=96% EIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKktnHVKAMRWPFQYNIGLKTND--KYVSLINYLPKNKIESTNVSQTL GYNIGGNFQSAPSLGG---NGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKS---AFDSDLFVGYKPHSKDPRDyFVPDSELPPLVQ SGFNPSFIATVSHEKGsSDTSEFEITYGRNMD-VTHAIKRSTHYGNSYLDGHRVHNAFVnrnytvkYEVNWKTHEIK-- >UniRef50_Q99SN7(72-336:351) Uncharacterized leukocidin-like protein 2 n=53 Tax=Staphylococcus aureus RepID=LUKL2_STAAN E=2e-31 s/c=0.52 id=22% cov=88% -----------------------FIDDPTYDKNVLLVKKQGSIHSNLKFEShkeEKNSNWLKYPSEYHVDFQ-VKRNRKTEILDQLPKNKISTAKVDSTF SYSSGGKFDSTKGIGRTSSN---SYSKTISYNQQNYDTIASGKNNNwHVHWSVIANDLKYGgevKNRNDELLFYRN---TRIATVENPELSFASKYRYPA LVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVK-- >UniRef50_B8K890(66-270:287) Leukocidin/Hemolysin toxin family n=7 Tax=Gammaproteobacteria RepID=B8K890_VIBPA E=7e-12 s/c=0.36 id=21% cov=60% ----------------------------------------------------------------------------------APENTIATASVSESLDFN LGFTASQSP-----SINAGVSWSNRVTYDQPEFQTVADfNQTNESISWLIENRTIRNHTPAKDW---------LLYRWTSCGMGNLVDYNELPIVMRSDF KPQVGAVYRKENindGQNTTDIKLVAGWRKTNYYFGRDWCSWY-TSYQNSWKKNRDSSHW----------- >UniRef50_Q6GF50(52-328:339) Uncharacterized leukocidin-like protein 1 n=53 Tax=Staphylococcus aureus RepID=LUKL1_STAAR E=6e-67 s/c=0.92 id=26% cov=98% -----TATTSDTEKKISQSLQFNFLTEPNYDKETVFIKAKGTIGSGLKILNPNGYwnSTLRWPGSYSVSIQNVDDNNNsTNVTDFAPKNQDESREVKYTY GYKTGGDFSINRGGLTGNITKEKNYSETISYQQPSYRTLIDQPTTNKgVAWKVEAHSINNmGHDHtrqltNDSDDRVKSEIFSLTRNGNLWAkDNFTPKN KMPVTVSEGFNPEFLAVMSHDKNDKgKSRFIVHYKRSMDDFKLDWNKHgfwgYWSGENHVDQKEEKLSALYEVDWKTHDVK-- >UniRef50_B7JDR2(50-332:337) Cytotoxin K n=43 Tax=Bacillales RepID=B7JDR2_BACC0 E=1e-65 s/c=0.89 id=29% cov=97% ----YNTFNNDQTDNMTMSLKVTFIDDPSADKQIAVINTTGsFLKANPTISSAPIdnypipgaSATLRYPSQYDIAFNLQD--NSARFFNVAPTNAVEET TVTSSVSYQLGGSVKASatpnGPSAEAGATGQVTWSDSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQnwgiYTRDSYHSLYGNQLFMYSRTYlyeSD AKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLrpgyTFGTANWVGNNVKDVDQKTFNKLFTLDWKNKKL--- >UniRef50_P55870(273-486:621) Hemolysin ahh1 n=79 Tax=Gammaproteobacteria RepID=HLY1_AERHH E=1e-17 s/c=0.43 id=19% cov=67% ------------------------------------------------------------------------SNTKAAVLKSLPTNLNSKYEHREISGFE VGvtGGVEVNKDGPKAKLEASakFSQQRQLAYNTQDYRVERSAPSAQK----VSFSWVRDQYA--------TAESLLSSKTATVWGMGYdVDHNRIQPLS YKGFVPNLDVIYKaAPDETGSTEFKIdSSVNIRPIYTGIYKHYYVVGahvsfqgfEDTDKRRRVTASTSFKVDW-NHPV--- >UniRef50_P19247(127-333:471) Cytolysin n=16 Tax=Vibrio RepID=VVHA_VIBVU E=0.0001 s/c=0.24 id=29% cov=25% -----------------------------------------------------------------------------------PQNENKNYQHRDTYGYS IgingkvGAEVNKDGPKVGGEVSGSftYNYSKTLVFDTKDYR---INNRSSLSDFDISF----------------------------------------- --------------------------------------------------------------------------- >UniRef50_P09616(55-317:319) Alpha-hemolysin n=54 Tax=Staphylococcus aureus RepID=HLA_STAAU E=4e-63 s/c=0.92 id=31% cov=91% ----------------------SFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKsgLAWPSAFKVQLQLPD-NEVAQISDYYPRNSIDTKEYMSTLT YGFNGNVTGDDtGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQnwgpYDRDSWNPVYGNQLFMKTRNGSmKAADNFLDPNKAS SLLSSGFSPDFATVITMDRKASKqqTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEM--- >UniRef50_C9NYC0(275-474:616) Cytolysin and hemolysin HlyA Pore-forming toxin n=1 Tax=Vibrio coralliilyticus ATCC BAA-450 RepID=C9NYC0_9VIBR E=7e-32 s/c=0.69 id=16% cov=70% ------------------------------------------------------------------DFNFNASNEKARILRTVPKsnlNKNYTNREISTF SFGVvaGGEASSDGAKGKLEASANWTESKWLSFETNDYRVDRHSNGPQHVG----FEWAREQY------PTAESVMVTTIHGYTAGITLPVDESRINKMG HASFLPKMEVIYSaAPDATGNTKFNIDSTvditgfRYMTNVTPFFGVRTYYAKDDDHQvNSVNKNINFVVDW-DHPV--- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * E 1 * * * 576 * * * * * * * * * 1603 * * * * * * 1 0 * * * * * * 2047 0 0 A 2 1645 * * * * * * 556 * * * * * * * * * * * * 2 0 * * * * * * 2047 0 0 I 3 * * * * * * * 0 * * * * * * * * * * * * 3 0 * * * * * * 2047 0 0 K 4 * * * * * * * * 401 * * * * * * 2043 * * * * 4 0 * * * * * * 2261 0 0 Y 5 * * * * * * * * * * * * * * 2716 * * * * 238 5 0 * * * * * * 3063 0 0 T 6 * * * * * * * * 2679 * * 2980 * 3182 * 3350 975 * * * 6 0 * * * * * * 3293 0 0 S 7 3558 * * 3018 * * * * * * * * * * * 1232 1450 * * * 7 0 * * * * * * 3293 0 0 S 8 * * 3018 * 2980 * * * * * * * * * * 1735 1560 3182 * * 8 0 * * * * * * 3293 0 0 D 9 2679 * 1358 * * * * * 2046 * * 2980 * * * * 3558 * * * 9 0 * * * * * * 3293 0 0 T 10 * * * * * * * 3075 * * * 2980 * * * 1770 1116 * * * 10 125 * 3591 * * * * 3293 0 0 A 11 2272 * 1961 * * * * 3023 * * * * * * * 1275 * * * * 11 175 3127 * 1000 1000 * 0 3266 1000 1000 S 12 * * 2572 * * * * * * * * 2029 * 2927 * 2136 2133 * * * 12 0 * * * * 0 * 3266 0 1000 H 13 * * * 1846 * * 3339 * 3018 * * 3679 * * * 2345 2153 * * * 13 0 * * * * * * 3293 0 0 K 14 * * 1347 * * * * * 1455 * * 3075 * * * * * * 3018 * 14 0 * * * * * * 3293 0 0 G 15 * * * * * 1149 * * 1625 * * 2980 * * * 3350 * * * * 15 149 3350 * 0 * * * 3293 1000 0 W 16 * * * * 2128 * * 2574 * 2679 2980 * * * * 3350 * 3018 3339 * 16 0 * * * * * * 3293 0 0 K 17 * * * * * * * * 904 * * 4025 * * * 2889 1893 * * * 17 0 * * * * * * 3584 0 0 A 18 2631 * * * * * * 1817 * * 3568 2656 * 2107 * * 3651 * * * 18 0 * * * * * * 3584 0 0 T 19 * * * * * * * * * * * 3364 * * * 407 2748 * * * 19 189 3029 * 1000 1000 * * 3584 1149 0 L 20 * * * * * * * 1541 * 783 * * * * * * * 3732 * * 20 0 * * * * * * 3584 0 0 S 21 * * 2616 3538 * * * * 2041 3651 * * * 2107 * 3765 3029 * * * 21 0 * * * * * * 3584 0 0 G 22 2616 * * * 1496 2647 * * * * * * * * * * * 1632 * * 22 0 * * * * * * 3584 0 0 T 23 * * 3449 * * * * * * * * 2066 * * 3613 1454 2167 * * * 23 0 * * * * * * 3690 0 0 F 24 * * * * 100 * * 3907 * * * * * * * * * * * * 24 0 * * * * * * 3841 0 0 I 25 * * * * * * * 430 * 3122 * * * * * * * 2807 * * 25 0 * * * * * * 3841 0 0 E 26 * * 810 2939 * * * * 2439 * * * * * * * 3122 * * * 26 0 * * * * * * 3841 0 0 D 27 * * 176 3122 * * * * * * * * * * * * * * * * 27 0 * * * * * * 3841 0 0 P 28 * * * * * * * * 1328 * * * 733 * * * * * * * 28 0 * * * * * * 3841 0 0 H 29 * * * * 4006 * 3990 * 2705 * * 1965 * * * 2525 3632 * * 2245 29 0 * * * * * * 3841 0 0 S 30 2862 * 3783 * * * 3741 * * * * * * * * 1897 3910 * * 1396 30 0 * * * * * * 3841 0 0 D 31 * * 646 * * * * * * * * 2170 * * * 2847 * * * * 31 0 * * * * * * 3841 0 0 K 32 * * * 2847 * * * * 216 * * * * * * * * * * * 32 0 * * * * * * 3841 0 0 K 33 * * 2439 3122 * * * * 1880 3783 2847 3632 * 2871 * * * * * * 33 0 * * * * * * 3841 0 0 T 34 3632 * * * * * * 2292 * 3741 * * * * * * 1020 3632 * 3910 34 0 * * * * * * 3841 0 0 A 35 1584 * * * * * * * * 1277 * * * * * * 2847 3122 * * 35 0 * * * * * * 3841 0 0 L 36 * * * * 3122 * * 1602 * 1771 * * * * * * * 1928 * * 36 0 * * * * * * 3841 0 0 L 37 * * * * * * * 1104 * 1644 * * * * * * * 2220 * * 37 0 * * * * * * 3841 0 0 N 38 * * * * 3910 * * * 1163 * * 2254 * * 3741 2890 3889 * * * 38 0 * * * * * * 3841 0 0 L 39 2194 * * * * * * * 3632 2308 3632 * * * * * 1258 * * * 39 0 * * * * * * 3841 0 0 E 40 3268 * 2274 2950 * * * * 1989 * * * * 2632 * * 2769 * * * 40 0 * * * * * * 3841 0 0 G 41 * * * * * 0 * * * * * * * * * * * * * * 41 468 1853 * 0 * * * 3841 2180 0 F 42 * * * * 1234 * * * * * * 2071 * * * 2764 2399 * * * 42 99 3910 * 1000 1000 * * 3841 1000 0 I 43 3910 * * * * * * 486 * 3836 2743 * * * * * * * * * 43 0 * * * * * * 3841 0 0 P 44 3741 * 3889 * * 3122 3632 * 3836 * * 4285 2338 * * 1783 * * * 4252 44 0 * * * * * * 3841 0 0 S 45 2292 * * * * 3741 * * * * * * * * * 472 * * * * 45 0 * * * * * * 3841 0 0 D 46 * * 3990 * 3910 1500 * * 2794 * * 2730 * 3741 3632 * * * * 3907 46 0 * * * * * * 3841 0 0 K 47 * * * * * * * * 2277 1932 3783 * 3836 * 4006 * 3632 * * 2023 47 0 * * * * * * 3841 0 0 Q 48 * * * 2743 * * * * 1694 * * * * 3990 2823 3907 1885 * * * 48 0 * * * * * * 3841 0 0 I 49 * * 3704 * 3632 * * 1405 2503 * * * * * * 3910 * 2821 * 3632 49 0 * * * * * * 3841 0 0 F 50 * * * 2763 2998 * * * * 3122 * 3889 2554 * * 3836 3783 3704 * 2685 50 0 * * * * * * 3841 0 0 G 51 4006 * * 3910 * 1890 * 3704 * * * 1740 * * * 2149 * * * * 51 339 2254 * 2090 386 * * 3841 2087 0 S 52 3836 * 3783 2685 * 2898 * * 3704 * * * 2194 * * 2998 3910 * * 3632 52 0 * * * * * * 3841 0 0 K 53 * * * 3741 * * * * 1099 * * 3122 2873 * * * * * * 2274 53 294 2439 * 1294 756 * * 3841 1667 0 Y 54 * * * * * 2399 3632 3029 * * 3907 2922 * * * 3910 * * 3783 1892 54 229 2769 * 2900 207 * * 3841 1670 0 Y 55 2823 * * * * * * * * * * 3889 * * 4006 1254 * 3632 * 2126 55 176 3122 * 1000 1000 * * 3841 1086 0 G 56 1885 * * * * 2338 * * 3632 * * 2685 * * * 2194 3704 * * * 56 0 * * * * * * 3841 0 0 K 57 2668 * * * * 3889 * * 2860 * * * * 2503 * 3910 2435 2955 3632 * 57 112 3741 * 1000 1000 * * 3841 1000 0 M 58 * * * * 3268 * * 3704 * 886 1844 * * * * * * * * * 58 0 * * * * * * 3841 0 0 K 59 3741 * * * * * * 3783 1848 * * 3704 * * 1609 * 3910 * * 3268 59 0 * * * * * * 3841 0 0 W 60 * * * * 3704 * * * * * * * * * * * * * 372 2730 60 0 * * * * * * 3841 0 0 P 61 3907 * * * * 3268 * * * * * * 270 * * * * * * * 61 0 * * * * * * 3841 0 0 E 62 * * * 3990 3632 2590 * 4006 * * * * * * * 859 * 3704 * * 62 0 * * * * * * 3841 0 0 T 63 2813 * * 3632 * * * * 2591 * * * * 2730 3704 2462 2883 3910 * * 63 0 * * * * * * 3841 0 0 Y 64 * * * * 2225 * * * * * * * * * * * * * * 347 64 0 * * * * * * 3841 0 0 R 65 * * 3836 * * * 2755 * 2823 * 4006 1993 * 3783 3990 2384 * * * * 65 0 * * * * * * 3841 0 0 I 66 * * * * * * * 1288 * 3783 * * * * * * 2900 1381 * * 66 0 * * * * * * 3841 0 0 N 67 3979 * 2220 3991 * 2360 * * * * * 4111 * 3866 3895 1885 * * * * 67 0 * * * * * * 4065 0 0 V 68 3991 * * * 2176 * * 2160 * 1953 2954 * * * * * * 3254 * * 68 144 * 3394 * * * * 4065 0 0 K 69 * * * 2307 * 3744 * * 2252 3706 * 2624 * 1865 * * * * * * 69 118 * 3665 * * 0 * 4010 0 1149 S 70 * * * * 3433 * * 2910 * 1836 * 1727 * * * 3162 3636 * * * 70 98 * 3924 * * 0 * 3941 0 1000 A 71 3989 * * 3770 * * * * * * * 2156 3762 3846 * 2528 2888 2414 * * 71 0 * * * * * 0 4007 0 1000 D 72 3498 * 1169 3032 * * * * 3714 * * * * * * 1898 * * * * 72 631 * 1497 * * 0 * 4007 0 1000 V 73 * * 2937 * * * * 3646 * 3884 * 3569 * * 3455 1375 3517 3765 * * 73 0 * * * * 786 1251 3932 0 2631 N 74 * * 4249 * * 3939 * * 3952 * * 291 * * * * * * * * 74 96 3952 * 0 * 0 * 4178 1000 1666 N 75 * * 2389 1995 * * * * 2485 * * 2297 * * 3930 4397 3984 * * * 75 0 * * * * * * 4352 0 0 N 76 4601 * * * * * * * 1637 * * 1687 * * * 2298 * 4043 * 3996 76 146 3375 * 0 * * * 4352 1086 0 I 77 1249 * * * * * * 4286 * * * * * * * 4190 2188 1977 * * 77 0 * * * * * * 4352 0 0 K 78 3052 * * 3930 * * * * 2274 * * 2460 * 2120 2915 3996 * * * * 78 0 * * * * * * 4352 0 0 I 79 * * * * 2210 * * 1070 * 3996 * * * * * * * 2030 * * 79 0 * * * * * * 4352 0 0 A 80 4286 * * * 4164 * 4159 3996 * 1637 * * * * * 4043 3375 2386 * 3260 80 0 * * * * * * 4352 0 0 N 81 * * 1272 * * * * * 1559 * * 2559 * * 3702 * * * * * 81 0 * * * * * * 4352 0 0 S 82 4159 * * * 3375 * * * * * * * * 3930 * 2182 2885 2200 * 2261 82 0 * * * * * * 4352 0 0 I 83 1190 * * * 4181 * * 3268 * 2471 * * * * * 4280 * 3106 * 4190 83 0 * * * * * * 4512 0 0 P 84 * * * * * * * * * * * * 0 * * * * * * * 84 0 * * * * * * 4539 0 0 K 85 * * * 4000 * * * 3302 876 * * * * 5349 3227 * 3199 4288 * * 85 189 3023 * 1096 910 * * 4539 1455 0 N 86 * * * * * * * * * * * 0 * * * * * * * * 86 0 * * * * * * 4539 0 0 T 87 4313 * * 3859 * * * 4233 2411 4094 * * * 2574 * 3257 1697 * * * 87 0 * * * * * * 4539 0 0 I 88 * * 3479 * * * * 931 * * 4288 1815 * * * * * 4313 * * 88 0 * * * * * * 4539 0 0 D 89 4000 * 2728 1433 * * * * 5349 * * * * * * 1885 4288 * * 3840 89 0 * * * * * * 4539 0 0 K 90 * * * 2960 * * * * 3246 * * 3685 * 4195 * 2047 1352 * * * 90 0 * * * * * * 4539 0 0 K 91 2513 * * * 3677 * * 4295 1772 * * 3840 * * 3479 * 3223 * * 2875 91 0 * * * * * * 4539 0 0 D 92 * * 3354 2030 * * * * 3150 * * 3185 * 3283 3840 4000 2324 * * * 92 0 * * * * * * 4539 0 0 V 93 * * * 3840 * * 3589 3271 * * * * * * * * * 536 * 4221 93 0 * * * * * * 4539 0 0 S 94 * * 4024 * * * * 3840 3479 * 4221 3379 * 3677 3589 1662 2719 * * * 94 0 * * * * * * 4539 0 0 N 95 * * 5349 2151 * * * * * * * 2792 * 2890 * 1391 * * * 3479 95 0 * * * * * * 4539 0 0 S 96 * * * 4288 * * * 4094 * * * * * * * 1925 673 * * * 96 0 * * * * * * 4539 0 0 I 97 * * * * 2929 * * 2834 * 2248 3244 * * * * 3162 * 2424 * 3130 97 0 * * * * * * 4539 0 0 G 98 * * 4000 * * 701 * * * * * * * * * 1895 4221 * * * 98 0 * * * * * * 4539 0 0 Y 99 * * * * 2035 * * * * * * * * * * * * * * 404 99 0 * * * * * * 4539 0 0 S 100 * * * 4094 * 3018 * * 2360 * * 2612 * 4313 * 1713 3260 * * * 100 0 * * * * * * 4539 0 0 I 101 * * * * 4221 * * 1602 * 2608 * * * * * 4024 3479 2161 * 3677 101 143 3406 * 1982 421 * * 4539 1503 0 G 102 * * * * * 80 * * * * * 4221 * * * * * * * * 102 171 3162 * 1000 1000 * * 4539 1348 0 G 103 5349 * * * 4000 131 * * * * * * * * * * * * * * 103 0 * * * * * * 4539 0 0 N 104 * * 2574 2788 * 2329 * * 4024 * * 2669 * * * 2272 4000 * * * 104 0 * * * * * * 4539 0 0 I 105 2431 * * * 2266 * * 1626 * 4494 * * * * * * * 2070 * * 105 0 * * * * * * 4539 0 0 S 106 * * 3259 2272 * * * * 2276 * * 3283 * 4139 * 1895 4221 * * * 106 0 * * * * * * 4539 0 0 V 107 4313 * * * * 4221 * 1906 5349 * * * * 4000 * 2411 4541 1684 * * 107 155 3292 * 2000 415 * * 4539 1589 0 E 108 4139 * 2757 3301 * * * * 3388 * * 2754 * * * 1567 3153 * * * 108 74 4313 * 2000 415 * * 4539 1000 0 G 109 * * 3265 4195 * 1768 * * 2529 * * 3045 2612 * 3479 * * * * * 109 178 4221 4000 0 * * * 4539 1000 0 K 110 3746 * 3069 4399 * 1493 * * 2746 * * 4115 2888 * * 4015 * * * * 110 68 * 4441 * * * 0 4397 0 1000 T 111 4165 * * * * 1881 * 3873 2136 2728 * 4122 * * * 3121 4215 * * * 111 0 * * * * * 0 4372 0 1611 A 112 2579 * 4165 * * 1900 * 4067 * 3353 * * 2074 * * 3523 * 5206 * * 112 0 * * * * * 0 4372 0 1611 G 113 * * 4122 4156 * 1300 * * 1919 * * * * * 3873 4329 3353 * * * 113 162 * 3239 * * 918 1087 4372 0 1611 A 114 1254 * * * * 1674 * * * 3636 * * * * * 3144 3763 * * * 114 0 * * * * 565 1625 4286 0 2061 G 115 * * * 3286 * 2090 * * 3969 4165 * 3380 * * * 1162 * * * * 115 77 * 4258 * * * 0 4557 0 1000 I 116 2419 * * * * 4207 * 1316 * 2221 * 4477 * * * 3843 * 5147 * * 116 91 4040 * 1000 1000 0 * 4499 1000 1634 N 117 * * * 3144 * 3409 * * * * * 1278 * * * 2402 2387 * * * 117 92 * 4024 * * * * 4539 0 0 A 118 951 * * * * 2101 * * 3372 * * * * * * 3323 * 4235 * * 118 0 * * * * * 0 4517 0 1000 S 119 * * * 2706 * 2542 * * 4531 * * 2116 * 4223 * 1525 * * * * 119 137 3462 * 1000 1000 * 0 4517 1564 1000 Y 120 4394 * * * 2500 * * * 2882 * 4235 * * * * 4531 * 2459 3697 1813 120 0 * * * * 0 * 4517 0 1000 N 121 2749 * * * 4625 * * * * * * 1898 * * * 1244 3057 * * * 121 60 * 4625 * * * * 4539 0 0 V 122 * * * 2957 4385 * * 4159 * * * * * 3103 * * * 2846 1881 2056 122 0 * * * * 0 * 4621 0 1000 Q 123 * * * * * 4221 * * 4288 * * * * 3246 * 340 * * * * 123 0 * * * * * * 4539 0 0 N 124 * * 4313 2191 * * 4221 * 1475 * * 2702 * * 4094 4195 4310 * * * 124 0 * * * * * * 4539 0 0 T 125 * * * * * * * * * * * * * 4094 4000 1714 988 * 3840 * 125 0 * * * * * * 4539 0 0 I 126 * * * * * * * 927 * 1945 * * * * * * 4310 2608 * * 126 0 * * * * * * 4539 0 0 S 127 4094 * * 4195 * * * * 4221 * * 3677 * * * 582 4000 5349 * * 127 0 * * * * * * 4539 0 0 Y 128 * * * * 2761 * * * * * * * * * * * * * * 230 128 0 * * * * * * 4539 0 0 E 129 * * 2406 2635 * * * 4195 2478 * * 2529 * 3479 * * 4139 3372 * * 129 0 * * * * * * 4539 0 0 Q 130 * * * * * * * * * * * * * 333 * * 2279 * * * 130 0 * * * * * * 4539 0 0 P 131 * * * 3677 * * * * 5349 * * 3840 1012 2120 * * 4313 4288 * * 131 0 * * * * * * 4539 0 0 D 132 * * 734 4000 * * * * * * * 3080 * * * 2196 * * * * 132 0 * * * * * * 4539 0 0 F 133 * * * * 2200 * * * * * * * * * * * * * * 354 133 0 * * * * 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