HHsearch 1.5 NAME c4eycA_ FAM FILE c4eycA_ COM /bmm/www/servers/phyre2/HH/hhmake -i c4eycA_.a3m DATE Sat Mar 2 08:28:08 2013 LENG 103 match states, 103 columns in multiple alignment FILT 115 out of 151 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 6.5 EVD 0.4324 -0.2266 SEQ >ss_dssp CCSCCBCCHHHHHHHHHHHHHHHCCCSEEEEEEEECCCCCCSCTTSCEEEEEEEEEEEEETTCCSCGGGSCBCTTCCEEEEEEEECSBTTSSCCEEEEET TCC >sa_dssp EEEDDDCDCEDAADDABDCBBEECEDECBBCCDECCEDEDEEDCCCEBDAAACACCAEADCECEDDDEEAEDDEEBDDCCADDCABBACDEEECEAECDD EDE >ss_pred CCHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCEEEEECCC CCC >ss_conf 9301115789999999999974187653067766201542467880699999985225334558997673346787046799999976886279996176 779 >Consensus xxxxxxlxyxeAvxxAixxxNxxsxxxxlfrlxxixxaxxqxxxgxxyxixfxixeTxCxkxxxxxxxxCxxxxxxxxxxCxxxVxxxpxxxxxxltCdx xxx >c4eycA_ GSHMQVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDK DNK >UniRef50_Q13103(39-134:211) Secreted phosphoprotein 24 n=14 Tax=Eutheria RepID=SPP24_HUMAN E=4e-18 s/c=0.96 id=22% cov=89% -------SLRDALSASVVKVNSQSLSPYLFRAFRSSLKRVEvlDENNLVMNLEFSIRETTCRKDSGEDPATCAFQRDYYVSTavCRSTVKVSaQQVQGVH ARC----- >UniRef50_O08677(35-125:661) Kininogen-1 light chain n=3 Tax=Eutheria RepID=KNG1_MOUSE E=7e-07 s/c=0.61 id=22% cov=83% ----------QAVDFSLKQFNPGVKSGNQYmlhRVIEGTKTDGSPTFYSFK---YLIKEGNCSAQSGLAWQDCDFKDAEEAAtgECTATVGKREnEFFIV TQTC----- >UniRef50_P24090(163-247:352) Alpha-2-HS-glycoprotein n=9 Tax=Eukaryota RepID=FETUA_RAT E=9e-07 s/c=0.64 id=15% cov=83% -----------TVKTALAAFNAQNNGTY-FKLVEISRA-QNVPFPVSTLVEFVIAATDCTGQEVTDPAKCNLLAEKQYGFCKATLIHRLGGEEVSVAC-- --- >UniRef50_Q4SMM7(27-126:318) Chromosome undetermined SCAF14546, whole genome shotgun sequence n=2 Tax=Tetraodontidae RepID=Q4SMM7_TETNG E=5e-12 s/c=0.72 id=22% cov=89% -------SSPEALRmaeEALEQVNQDRTDGYILslnRLYDISHTPETEGGALVYKLSIDVMETECHIISRKPWKQCEVKsiaKAPVYGECEMSIYVDSEV KLQSYTC----- >UniRef50_Q9D264(36-130:133) Novel protein containing a Cystatin domain n=3 Tax=Murinae RepID=Q9D264_MOUSE E=3e-06 s/c=0.56 id=16% cov=90% -------SEPDIVKFALSAFHKKSKDEYAYRVIHIMNfLKVQEEPPQTFFVKLRLTRTICMKFE-KSLDTCPLPELQNILICSFSISSpgSKQFNLLKMT CSE--- >UniRef50_UPI00016E6254(40-128:302) UPI00016E6254 related cluster n=1 Tax=Takifugu rubripes RepID=UPI00016E6254 E=6e-05 s/c=0.55 id=21% cov=71% ---------------AIHHINENHDHGYKFKIDEVTEVDLKmVDNGCDIMLQLLLKETACHTISPRDFEECRERSLGEravVANCSVLITV--------- ------- >UniRef50_O08677(156-247:661) Kininogen-1 light chain n=3 Tax=Eutheria RepID=KNG1_MOUSE E=3e-11 s/c=0.76 id=19% cov=87% ---------EPVLKHSIEHFNNNTDHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERFPSLHgDCVALPNGDDGECRGNLFMdiNNKIANFSQS C----- >UniRef50_Q4ZJ77(38-133:133) Cystatin n=2 Tax=Xenopus RepID=Q4ZJ77_XENLA E=3e-12 s/c=0.76 id=20% cov=87% ---------QKAMTFAMQEYNKQSNDMFLNTITKVNGVTKQLVSGTVYRIDAVVSRTECKK-SAVGVQNCPVHTDGNFaksMNCQFEVLTIPWQRENKLq kkTCD---- >UniRef50_B7PKZ1(34-121:132) Secreted cystatin n=3 Tax=Ixodes scapularis RepID=B7PKZ1_IXOSC E=7e-05 s/c=0.55 id=18% cov=44% --------------------------------------------GTNYRLTLKVAESTCELTSTYNKDTCQANANAAQRTCTTVIYRN------------ --- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * G 1 * * * * * 0 * * * * * * * * * * * * * * 1 0 * * * * * * 1000 0 0 S 2 1000 * * * * * * * * * * * * * * 1000 * * * * 2 0 * * * * * * 1511 0 0 H 3 * * * * * * 1000 * * * * * * * * * * * * 1000 3 0 * * * * * * 1511 0 0 M 4 2025 * * * * * * * * 975 2025 * * * * * * * * * 4 0 * * * * * * 2215 0 0 Q 5 * * * 3357 * * * * * * * * * 707 2398 3321 * * * * 5 0 * * * * * * 3212 0 0 V 6 3036 * 2496 * * 4259 * * * * * * * 3590 * 1449 3840 2949 * * 6 0 * * * * * * 3237 0 0 L 7 * * * * * * * 3481 * 302 * * 4519 4169 * * * * * * 7 0 * * * * * * 3985 0 0 S 8 * * * 4501 * * * 4418 * 3587 * 4471 * * 2528 887 3907 * * * 8 0 * * * * * * 4873 0 0 Y 9 * * * 3807 * * * * * 3920 * * * * * 3982 * 3318 * 517 9 0 * * * * * * 4926 0 0 K 10 * * * 1448 * * * * 3153 4810 * * 3847 1718 3158 * * * * * 10 0 * * * * * * 6474 0 0 E 11 6113 * 3094 1351 * 5694 5617 * 2093 * * 4729 4660 3515 5424 * 6133 * * * 11 0 * * * * * * 6637 0 0 A 12 667 * * * 5232 * * 4548 * 4716 4622 * * * * 4967 3480 3312 * * 12 0 * * * * * * 6866 0 0 V 13 2094 * * * * * * 4786 * 1849 5989 * * * * * 5774 1259 * * 13 0 * * * * * * 6898 0 0 L 14 4202 * 3172 3415 * 6284 * 6100 3690 2995 * 2971 * 3307 3635 3657 3961 4534 6067 * 14 18 6360 * 1585 585 * * 6898 1000 0 R 15 2595 * * 3053 2698 6384 4261 * 3621 3982 5934 5570 * 5178 2958 5481 4720 4180 * 4576 15 0 * * * * * * 7036 0 0 A 16 392 * * * 5129 4399 * * * 6140 * * * * * 3145 4846 * * * 16 0 * * * * * * 7154 0 0 I 17 6473 * * 6110 * * * 2343 * 1529 3282 * * * * * 5513 1709 * * 17 13 6787 * 2000 415 * * 7101 1000 0 D 18 3009 * 2647 2523 * 5619 4815 7639 4491 6193 * 4535 * 3330 3706 5011 3267 6401 6411 4462 18 0 * * * * * * 7113 0 0 G 19 3616 * 5191 2731 4820 5921 3665 5539 2182 4048 * 4896 * 3154 4880 4818 4936 * 6169 4457 19 0 * * * * * * 7113 0 0 I 20 * * * * 1519 * 5523 2948 * 3977 * * * * * * * 3616 * 1495 20 0 * * * * * * 7113 0 0 N 21 * * * 5706 * * 6050 * * * * 76 * * * 5864 * * * * 21 0 * * * * * * 7113 0 0 Q 22 3650 * 5995 3587 * * * 5131 2103 6377 * 3147 6117 2490 3987 2604 7388 * * 6751 22 0 * * * * * * 7113 0 0 R 23 3667 6389 3971 2835 * 3314 * 5717 2801 5484 4832 3552 * 2145 4000 * * 6486 * * 23 0 * * * * * * 7113 0 0 S 24 * * 6681 * * * 5394 5180 * 3486 7639 3873 5614 5091 3503 923 3756 6117 * 5484 24 19 * 6276 * * * * 7113 0 0 S 25 4447 * 4174 4541 * 4544 * 4852 3793 5657 * 1719 4560 3554 4439 3404 4239 4862 5202 * 25 0 * * * * 0 * 7099 0 1000 D 26 4541 * 1650 3882 * 2726 4432 * * 6305 * 4186 * 6849 5483 2299 5704 5582 5947 6063 26 12 6923 * 0 * * * 7113 1000 0 A 27 3336 * 3651 3391 * 2559 * * 3563 3603 4926 4127 4237 4790 4992 3429 3751 * * 6411 27 0 * * * * * * 7113 0 0 N 28 5593 5831 * * 3312 * 3410 * 4777 * * 1808 5599 * 3709 3990 * * * 1812 28 97 4867 5032 1585 585 * * 7113 1910 0 L 29 3622 * * * 6403 * 3987 3945 3499 1012 * 6467 * 4838 * 7015 * 3957 * 3711 29 0 * * * * 0 * 7103 0 1558 Y 30 * * 5709 * 874 * 5951 * * 3948 * 6498 * 5717 6135 4965 * * 4607 2078 30 36 5354 * 1999 415 * * 7125 1712 0 R 31 4719 * * 4837 * 4658 * 5718 2074 6309 5358 * * 4826 1339 6386 3679 3997 6549 * 31 0 * * * * * * 7125 0 0 L 32 4306 * 6326 5600 * 6444 * 3069 6772 818 6500 5841 3853 * * * * 3160 * * 32 0 * * * * * * 7125 0 0 L 33 * * 3664 5045 4805 5095 4941 3810 6749 2084 5254 3821 * 5883 4524 3018 4578 3016 * 5033 33 0 * * * * * * 7119 0 0 D 34 4254 6385 4105 2193 * 4709 4068 5602 3030 7389 * 4727 * 4834 2198 3633 6290 5165 * * 34 24 5893 * 0 * * * 7120 1000 0 L 35 3129 * * * 5215 5484 * 1659 * 3179 * * 5519 5893 * 4754 4610 1773 * * 35 14 6667 * 0 * * * 7120 1000 0 D 36 6278 * 3125 4017 * 4763 4964 3856 4343 3203 4794 4244 * 5051 6290 2724 2796 4608 5487 5354 36 31 5560 * 361 2176 * * 7120 1621 0 P 37 4548 6328 3512 3472 * 5436 5442 4670 3181 5165 6183 4781 2934 5348 2874 3008 5301 4803 * 5963 37 42 6050 6183 0 * * * 7120 1000 0 R 38 1263 * * 4927 * 6098 * 5052 4097 5196 5708 * 3475 4196 4332 4869 5160 2790 * * 38 136 4150 4882 915 1090 * 0 7101 2467 1000 T 39 4255 * 4935 3389 6748 * 4019 * 2711 5474 4730 5686 2855 3152 4258 3298 3306 6592 * * 39 179 3763 4536 3586 125 865 1149 7072 3140 2508 M 40 * * 5708 3602 6229 4603 * 4259 3155 3303 5649 6989 4239 5495 2503 3368 3471 3894 4487 * 40 64 4983 6382 347 2227 0 * 7054 1823 2722 D 41 5863 * 2956 4470 * 4487 5516 5694 4429 * * 4435 6522 1103 5840 3964 4854 4718 * * 41 118 3956 6129 988 1012 0 * 7108 2966 1000 G 42 * * 4354 4496 * 3703 * 3763 5251 2559 4552 4068 4650 5172 6792 5250 5880 1847 4054 * 42 9 * 7360 * * 546 1666 7120 0 1329 D 43 * * 2965 3174 * 3720 5699 5864 6279 5058 6315 3358 4700 * 5714 4036 3406 1888 6288 * 43 0 * * * * * 0 7108 0 1607 P 44 2683 * 4242 5423 4258 4900 * 5278 3803 4775 5699 2950 2937 * 5548 2819 3850 4767 * * 44 35 5385 * 638 1484 * 0 7108 1752 1607 D 45 5218 * 4303 5219 * 870 6469 6321 5297 6298 6716 6418 3656 5105 4552 4329 6381 * * 4247 45 0 * * * * * 0 7305 0 1607 T 46 5114 6291 4978 5234 4816 4537 6429 2944 4638 2790 5905 6192 4693 5177 5273 3921 2314 3590 6753 6236 46 0 * * * * * 0 7305 0 1607 P 47 4949 * 5240 4805 4315 * 3674 4834 3390 3139 * 2547 4959 5117 3247 4574 4864 3069 * * 47 13 * 6837 * * * 0 7305 0 1607 K 48 * * 6199 * 2498 * 6409 3886 3748 6598 4210 4849 * 6581 4713 5732 4208 6313 * 1243 48 152 5696 3635 0 * 603 1549 7282 1000 1403 P 49 5316 * 4816 4460 2745 * 6480 5027 3794 3609 5275 5240 3561 7623 2837 3041 4913 5994 * 3374 49 0 * * * * 1075 929 7183 0 3466 V 50 5754 * * * 4289 * * 1944 * 1471 4631 * * * * * 6181 1969 * * 50 0 * * * * * 0 6836 0 2494 S 51 * 6086 3625 1964 4924 * 5588 6458 2892 * 5798 3567 * 3797 4253 3648 3010 * * 5828 51 0 * * * * 340 2252 6836 0 2494 F 52 4649 * * * 1124 * * 3865 * 3043 4399 * * * * 6360 6553 2865 * 3269 52 0 * * * * * 0 6842 0 1607 T 53 4691 * 3211 2649 * 6239 6580 4011 3877 3785 * 5048 * 4724 3345 4052 2424 4530 * 6475 53 14 6729 * 1000 1000 * 0 6842 1000 1607 V 54 6356 * * * * * * 1194 * 2505 3641 * * * * 5301 4564 2141 * * 54 25 6650 7079 1000 1000 * 0 6690 1000 1607 K 55 2593 6595 * 4438 * 2884 6583 * 2460 4228 4953 * * 4385 3314 3830 5851 3119 6227 * 55 0 * * * * * 0 6692 0 1372 E 56 4408 * 5468 1027 * 6459 * * 3022 6197 * 6517 4049 4719 2897 6509 * 6275 6403 6360 56 0 * * * * 553 1651 6709 0 1372 T 57 * * * * * 4214 * * * * * * * * * 2624 394 5437 * * 57 0 * * * * * 0 6703 0 1607 V 58 4545 * 2559 3097 5815 6120 * 4553 4877 7082 6568 2833 4545 5603 6153 4399 2962 2733 * * 58 0 * * * * * 0 6703 0 1607 C 59 * 0 * * * * * * * * * * * * * * * * * * 59 0 * * * * * 0 6702 0 1607 P 60 5390 * * 6086 6671 4833 3968 6168 2701 3780 6647 5867 2479 5743 3107 2912 3181 5167 * * 60 35 * 5400 * * * 0 6741 0 1607 R 61 3892 * * 5985 6165 6510 * 5112 856 6039 * 6987 6742 * 3404 5142 5342 3033 6855 * 61 197 3767 4210 750 1303 1216 812 6682 2982 1927 T 62 3549 * 4747 3425 4892 5426 * 4178 4063 4463 5740 4035 4692 4180 4877 2982 2440 4366 * * 62 122 3839 6495 1523 617 1066 937 6558 3268 2918 T 63 4000 * 3321 1821 * 3975 6410 * 5301 4659 * 6225 * 4646 6218 1680 5759 5902 * * 63 90 5203 4894 0 * 1451 657 6678 2040 1965 Q 64 4396 * 3826 3540 4395 2522 3895 * 3611 5958 * 3469 3707 4015 3462 5311 4665 5309 * * 64 91 6212 4401 1000 1000 540 1678 6686 1584 3406 Q 65 5801 5373 5689 3357 * * * 5047 2540 4289 * 4690 5119 3800 2697 4177 3359 3922 * 3729 65 78 5395 5128 1427 671 434 1945 6654 2141 3263 S 66 4378 * 2170 3977 5465 6574 6481 5919 5100 4781 5143 2447 3259 4675 * 2872 4388 * * * 66 52 6682 5295 2322 322 * 0 6627 1000 2545 P 67 4888 6309 * 6977 5104 6001 5833 4547 5128 1513 * 6808 2555 6888 5124 5675 * 3510 2854 * 67 43 5273 8111 0 * 406 2028 6620 1663 3321 E 68 3823 * 2823 1980 5710 6165 5268 6428 3814 * 5521 * 5728 3674 3787 3216 3772 5602 * * 68 38 5261 * 0 * * 0 6752 1288 2007 D 69 4741 * 2331 3647 * 4425 5728 5062 4839 5008 6518 2417 * 3254 3921 3639 3768 * * * 69 75 4687 6362 504 1761 1233 799 6752 2097 2007 C 70 * 53 * * * * * * 4797 * * * * * * * * * * * 70 54 4770 * 692 1392 1153 862 6729 2221 1929 D 71 3144 * 2454 2684 * 6715 6197 * 3401 4949 * 3790 2522 4360 4534 6553 * 4826 * 6105 71 47 5930 6009 1585 585 * 0 6938 1535 1577 F 72 4110 4901 * 5025 1310 * * 4311 * 2739 * 5877 3493 * * 4338 6029 4025 * 4563 72 26 5781 * 615 1527 1685 537 7073 1611 2034 K 73 5004 5709 5740 * * * 5069 * 1715 2693 5122 4420 4485 2599 3312 4843 5554 * * * 73 43 5076 * 1414 679 731 1331 7541 2124 1531 K 74 3346 * 2884 1928 * * 6671 * 3421 5610 * 4366 4064 3757 5518 5033 3585 4421 6054 * 74 40 5187 * 0 * * 0 7566 1818 1607 D 75 4771 * 2178 3590 * 3011 6392 6224 4560 4624 * 2504 5730 4990 5439 3098 4306 * * 6633 75 28 5713 * 1000 1000 * 0 7062 1748 1607 G 76 3285 * 4642 3750 5672 1510 6408 6390 4717 6330 5139 6028 3572 4833 4874 5054 4565 4125 * 6457 76 49 5459 6588 1285 762 0 * 7185 1698 1607 L 77 3859 * 5115 2683 3974 5055 4610 6354 4090 2871 6849 4662 3588 3798 5030 * 4261 3222 * 6499 77 98 4496 5567 1437 665 0 * 7126 2491 1000 V 78 6663 * 5254 3957 5382 * 4330 4899 4776 2199 5255 6809 5514 4417 4840 4693 4263 2079 * 3799 78 52 4811 * 1404 685 * 0 6986 2342 1468 K 79 3253 * * 6087 * 2310 5746 * 2470 4277 4021 5383 5686 3969 2640 5269 6546 4235 * 6801 79 95 3966 * 970 1030 * 0 6958 2858 1468 R 80 6027 * 4079 2879 4508 6260 4945 4263 3404 3616 * 3192 * 2748 4412 4612 3208 * * 5813 80 176 3120 * 1347 721 0 * 6958 3689 1468 C 81 * 0 * * * * * * * * * * * * * * * * * * 81 0 * * * * * * 7301 0 0 M 82 6404 * 5801 4236 4387 * 5356 3936 3703 5503 5810 3251 * 3462 3313 3110 2299 4632 7107 * 82 40 5861 6618 1000 1000 * * 7217 1000 0 G 83 1929 * * * 2324 1940 * * * 6249 5460 * * * * 3336 4572 3322 * * 83 0 * * * * * 0 7166 0 1000 T 84 4518 * * 3363 * * 4713 4236 5316 5275 6983 5190 6319 4379 4593 2720 1866 3037 * 4981 84 17 6416 * 0 * * 0 7166 1000 1000 V 85 7099 * * * 3864 * * 2513 * 3407 5936 * * * * * * 681 * 6102 85 18 6327 * 0 * * 0 7165 1000 1000 T 86 * * 3831 5409 3578 4160 5819 4808 6227 3926 * 4974 6097 * 4821 2705 3217 4872 2874 3050 86 0 * * * * 0 * 7275 0 1000 L 87 3688 * 6204 3746 4876 * 5132 3807 4238 3136 3967 6760 5259 * 3560 3990 3764 2341 * 6005 87 75 4294 * 752 1300 * * 7266 2335 0 N 88 4622 * 3961 3501 * 4999 * 4478 4664 4306 * 3021 5511 5197 2097 3621 4291 3505 * 6138 88 36 5327 * 478 1827 * * 7268 1701 0 Q 89 5573 * 4720 5175 6283 6322 5715 * 3953 4324 * 5620 1171 3416 4345 2894 6299 * * * 89 56 4709 * 400 2047 * * 7212 2278 0 A 90 5065 * 3485 3489 * 3328 * * 5620 * * * 5884 3143 4907 3680 5186 * 1312 * 90 158 3609 5519 1231 801 * * 7212 2723 0 R 91 5214 * 4386 3992 2850 3927 6030 3020 4676 3108 4720 3631 5987 5169 5075 6402 3479 3817 * * 91 17 6386 * 1585 585 0 * 7151 1000 1000 G 92 3075 * 3694 2907 6275 4677 * * 3574 * * 2677 2713 4966 3722 5312 3683 6054 * * 92 86 4104 * 1169 849 * * 7207 2727 0 S 93 5097 * * 2432 4971 5823 5997 3844 3865 3823 * 3678 * 3252 * 3534 4374 2368 * * 93 21 6093 * 1000 1000 * * 7157 1000 0 F 94 3575 * 6561 6122 2948 5406 * 3407 4848 3446 4611 5016 * 3868 5384 6609 4754 1952 * 4404 94 50 4862 * 562 1632 * * 7052 1594 0 D 95 4638 * 3044 4285 * * 4906 5151 2930 * * 4359 * 5921 5226 2015 2626 3420 * * 95 0 * * * * * * 7052 0 0 I 96 4912 * * * 5989 * * 2826 * 1366 4977 * * 3251 * * * 1991 * 4889 96 228 2776 * 1585 585 * * 7052 3335 0 S 97 5628 * 5680 5491 * * * * 4906 * * 3198 * 3777 3263 2483 1321 5799 * 5540 97 65 4513 * 1850 469 * * 6701 1595 0 C 98 * 0 * * * * * * * * * * * * * * * * * * 98 0 * * * * * * 6673 0 0 D 99 * * 1045 2792 * 4372 4107 * 5004 5724 * 3441 * * 5234 3870 5181 * * * 99 0 * * * * * * 6029 0 0 K 100 * * 3279 1725 * 2675 * * 3012 * * * * 3294 2680 4158 * * * * 100 0 * * * * * * 5339 0 0 D 101 2719 * 1014 * * 4517 * * * 4876 * * 2368 * * * * 3616 * * 101 0 * * * * * * 4653 0 0 N 102 4451 * * 2893 * * * 3461 2773 * * 3802 * 2581 3686 1910 * * * * 102 0 * * * * * * 3680 0 0 K 103 * * * * * * * * 843 * * * * * 1176 * * * * * 103 0 * * 0 * * * 2949 0 0 //