HHsearch 1.5 NAME c3dhyC_ FAM FILE c3dhyC_ COM /bmm/www/servers/phyre/brandnew/HH/hhmake -i c3dhyC_.a3m DATE Tue Mar 9 11:22:10 2010 LENG 485 match states, 485 columns in multiple alignment FILT 121 out of 126 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 5.1 EVD 0.3399 -7.1853 SEQ >ss_dssp CCCEEETTEEEEESCGGGHHHHHHHHHHHHTTCHHHHHHHHHTTTTCTTTTCEEEEESCCSHHHHHHHHHHHHTTCEEEEECSSTTCCCHHHHHHHHHTT TCCSSSCCSCCEEECSSCCHHHHHHHHHHHHCCSCTTSCCCEEEESSSHHHHHHHHHHHHHHHTCCCCCCTTSCHHHHHHHHHHHHHHHHCSSHHHHHHH HCCCEEECSHHHHHHHHHHHHTTCCCSCEEECTTSHHHHTTHHHHHHHHHHHHHHHHHCCCCCTTSEEEEECCSHHHHHHHHHHHHTTCEEEEECSCHHH HHHHHTTTCEECCHHHHGGGCSEEEECSSCSCSBCHHHHHHSCTTCEEEECSSTTTTBTHHHHHTTTCEEEEEETTEEEEECTTTCCEEEEEGGGSBHHH HSSCCSCHHHHHHHHHHHHHHHHHHHHTGGGCCSSEECCCHHHHHHHHHHHHHHHTCCCCCCCHHHHHHHTCCTTSCCSCTTCCC >sa_dssp EECDEDDEBCBCBDDBECBEDABEDADEACEDACAACCACEDCDEEDBAEDACAAABABABBBAAAAABAADDACBEBBABBBBBBAABCBAAAAAABBD ECDCEDADCBBAAABDDBDCECBBCABBCAACBEDEEECABAAAABBBBBBBAABCBBDBBEEEEBCEDEEECEECDDBAADCBCECCEEDEDBACEBBE CBCAAAABCDCABDCADEBDEEEDBDABAAAAADBCBABCDBBCDABDEAACCAADDBBECEACDCDBAAABBCCCACAAACBADEDDBDBCABCEDEEC CEDAEEDEBECCDBEECBDEBCAAAABDCEEDCACCEBACDADDEABAAABCBCCDAACBECAEEDECEDEDEDEBBACBCBEEDEDBACAAACABCABB ABBDACCCCCBABAAAAAABAABBACDDCEECEEDCCEBDBEBBBCACCCBDDDEEDEEEECDEEDAEEEECEBEBDCDDEEDED >ss_pred CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCC CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCC CCCEEEEECHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHH HHHHHHCCCCCCCHHHHHHHCCEEEECCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEECCCCEEEE ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEHHCCHHHHHHCCCCCCCCCCCCCCCC >ss_conf 9730115887232040008876899999995479999999973037986786699750356889999999986698499970688777325888863022 2233111585567507999999999999985056677787389866224322330232010013466543342012233444320000113012255303 4320575410368999998607985203786132001112333221112589999875086655665999816833389999976169829998387305 6787642732236888872089999944975357988998469984999804777531888985122100320365148985589963899416743234 1688873788889999999999999857783464201486788888999677860864111494578753751356848453469 >Consensus xxxxxxxxxxxxvxdxxlaxxGxxxixxaxxemPxlxxxxxxxxxxxplxGxxIxxxlhlxxxTaxlixtLxaxGAxvxxxxxnxxstqdxvaaxlxxxx xxxxxxxxGixVfaxkxetxxeyxxxxxxxlxxxxxxxxpxxilDDGgdltxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxlxxxxxxxxxxxxxlxx xixGxxExTxtGvxrlxxxxxxxxlxxPvxxvndsxxKxxxdnxxgxgxsxxdxlxRxtxxxLxGKxvxViGyGxIGrgVAxxlraxGxxVxvxdxdpxx axxAxxdGxxxxxlxexlxxaDiIvtaTgxxxiIxxexlxxMKxgaiLxNxgxxxxEIDxxaLxxxxxxxxxvxxxvdxxxxpxxgkxixLLaxGxxvNL xxxxGxpxexmdxsfAxqxlaxxxLxxxxxxxxxgVxxlPxxidexvAxlxLxxlgvxltxLTxeqxxylgixvxGpxkxxxxxx >c3dhyC_ LTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGP HGTPDEPKGVPVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFETDKDKWTKIAE SVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPIN ALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNL GNATGHPSFVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY >UniRef50_D1V7F3(4-221:304) Short-chain dehydrogenase/reductase SDR n=2 Tax=Frankia sp. EuI1c RepID=D1V7F3_9ACTO E=1e-15 s/c=0.40 id=21% cov=41% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----------------------------------------------------------DLGLAGKAAVVTGAGaGIGQAIARGLAAAGVRVGLVEIDPT RA-AATVELIEKEGGQALALQADVMDTAALT-DAITATHTEFGRLDILVNNAGgvkasrfldqserswRRHIDINlVSMLAATSTAAPLIAQTVAAAAEA SGGRP----TGGSIVNITSIEGMRAAPM---YAVYAACKAGMINFTRTM----------------ALELADSGIRINAIAPDLTATAGIRgiMRGPVDPD ---- >UniRef50_C9L4S7(62-373:879) Pyridine nucleotide-disulfide oxidoreductase/rhodanese domain protein n=3 Tax=Bacteria RepID=C9L4S7_RUMHA E=0.0004 s/c=0.16 id=23% cov=41% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----------------------------------------------------------------KKAVVIGAGFIGLEVAENLKAKGIQVTVIDFASQI LPNIVDAEVAVYAKKHLLKEGIRVITGTKADAIMGNDHVTGVKTSAGLLRCEllimAAGIRPNTDFLQDSGLEMFKGTILVDK-TMKTNLEDVY--AAGD CVMVTNRiTGKPQwSPMGSSANLEGRTLAQVLTGTKKEYPGVLGTGV--------VKLPNLNIGRTGLTEEQAKNAGYDV----------- >UniRef50_UPI0000DB72A4(139-381:478) PREDICTED: similar to 3-phosphoglycerate dehydrogenase n=2 Tax=Apocrita RepID=UPI0000DB72A4 E=2e-29 s/c=0.55 id=19% cov=45% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- --------------------------------------------------------------LSGKTLAVLGMGRIGREVTRRMQAYGMRVIAFDP-LLT SEDANYLNVEKFSLDEIWPMADYITVHTPlipqTKNLINATTLAKCKKGVRIINVARGGI-VDEEALLNALKSGHCAGAALDVFTEEPPKNSVILELIAH PkVISTPHLGASTEEAQQRVAEE-IAQQFLVLAGRSTEyviTGIVNAPmlsaAISDENASWIELsKKLAVLVGILSgqtknglnlinaPTLAQEIGIDIK RSYEE----- >UniRef50_C6N370(107-335:357) Erythronate-4-phosphate dehydrogenase n=2 Tax=Legionella RepID=C6N370_9GAMM E=2e-22 s/c=0.48 id=18% cov=42% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------HLIQGNKAGIIGFGKVGSQVAARLQAAGFELLTYD--PLK ELR-EPNTFQSCQFDD-LSQADLLCIHAelhdtqphPSLNLINQPFLEHLKSGCVIINAARGGIINEEALLNNHKTLSYCTDVYLNE---PAVDQRIIER TTLCTPHIAGHSLEAKYLAvamvserlhqiiglpSPQFAIPELKHIFALKNDKTWEENVLSIYNPLDETI----------LLKEATDKESAFLTLR---- -KNHHQRH >UniRef50_D1RG91(41-370:389) Putative adenosylhomocysteinase n=1 Tax=Legionella longbeachae D-4968 RepID=D1RG91_LEGLO E=7e-49 s/c=0.60 id=24% cov=65% ------------------------------NEAPFMHQQLTEWSVTRPLAGLRILHHVPVVVNTLLKIACLIEAGA------------------------ ------------------------------------------------DVTVTNPSDFCHAHPRAVSALKEANVRYVETPLSLVGDKFDLYYDCGAQLYQ flgaPKIGAIELTGSG----DDFYRHQDLDFPVISIDRTLTKQL-ETVFGCAESSHMALTKLTGIPPNETSWIIFGFGKIGRGVAYFCNQNKIPVTVVDI CETQRGFAKKLGIQAINpknfndLERALIRANVIITATGKKAILN-DYPHSWFSGKILANLGVYD----------------EFGPHFSEDE--------- VLNHKMPVNFVLEDPTPMKYIDPEFYIHNFASLMLVK--EKLTNGVHGIPGEIDQNI-------------------------------------- >UniRef50_C7Q1U7(123-473:500) S-adenosyl-L-homocysteine hydrolase, NAD binding n=1 Tax=Catenulispora acidiphila DSM 44928 RepID=C7Q1U7_CATAD E=3e-37 s/c=0.45 id=23% cov=61% --------------------------------------------ADKPLGECGVVLVGHLLSDLVVQAQTLMALGARpeamTVLAKDYPYKLRARVEAHL ASL---------GIAVLPVADAEIALRLHAARVV--------EPSVVIDDGGHV-------------------------------------LPTLMKLAP DLLPRFQGLVEQSLPGIEELEVAEEAMPVPVPVFSVAQSAVKRGVE-----AHWIAESVVRAIRELLAGENfdgapALVVGYGMVGEQVAQVLRTQRMRV AVHDTEWRKLVAAHEAGFLTAPDLPALLDGHrpaLIVSATGRTG-LGGEDLDFLPGDCFLASVSARGTEIDMPGLAERAERVEEVAHVGMRYVLPNG--P VTVLADGLSVN-------------------------------------------------------------------------------------- >UniRef50_Q1ZK07(144-397:401) Putative uncharacterized protein n=2 Tax=Photobacterium RepID=Q1ZK07_PHOAS E=5e-32 s/c=0.56 id=20% cov=37% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------VIGAGNLGRGVIKHLKAKGItNIHVTDIDPR KLTQFPRDGIQACSIKYLVEHCNMLFCCTGNQS-ITPEMIDALSQPIFISTVTSADDELHLPDLLQQGVLTEVKTNRLTKEYKTRHGHSVYLFAGGESAN tpFKTGMGDPTLYLFE--AAHMLAGLELIKDATQFKPGIQSLCEDDEIMIAE------------------------------------ >UniRef50_Q054V2(340-813:819) Putative uncharacterized protein n=4 Tax=Leptospira RepID=Q054V2_LEPBL E=4e-27 s/c=0.26 id=18% cov=51% ---------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------LMQ TLVGSVEHTRNGYDRLKSVQdKNQKLFLPSFSIAISDQKVREESKEVAYSilNAIEAILNGQGMILSSRKVLILGAkGNIGSYLCKylesRLHETNQDLI QVDIQFSKSERFNCRTIGEIEREEFLSR-DLILGVVGC-SILKREHFEDLilngtKSKILIASGSTKTAEYTdlIHWLDELSFSEDKkigghpVRLEFDR ILDPQSGidqggkvsffvskdgveieKTFFLLSDLSPINF-LFYGVPTEGMDAiigQLASVALGMADQSKNGRILPPGLYAVDHEID------------- ---------------------------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * L 1 * * * * * * * * * 551 1655 * * * * * * * * * 1 0 * * * * * * 1535 0 0 T 2 * * * * * * * * * * * * * * * * 604 1547 * * 2 0 * * * * * * 1535 0 0 P 3 * * * 1547 * * * * * * * * 604 * * * * * * * 3 0 * * * * * * 1535 0 0 D 4 1655 * 1556 * * * * * 1547 * * * * * * * * * * * 4 0 * * * * * * 1535 0 0 V 5 * * * 1655 * * * * * * * * * * * * 1547 1556 * * 5 0 * * * * * * 1535 0 0 R 6 * * * * 1655 * * * * * * * * * 1556 1547 * * * * 6 0 * * * * * * 1535 0 0 N 7 * * * * * * * * * * * 414 * * * 2003 * * * * 7 359 * 2183 * * * * 1934 0 0 G 8 2453 * * * * 291 * * * * * * * * * * * * * * 8 0 * * * * * 0 2097 0 1000 I 9 * * * 3671 3042 * * 1833 * 2416 3096 * 3516 * 2970 * * * * * 9 0 * * * * 0 * 2851 0 1000 D 10 * * 873 3035 * * * * 4544 * * 2595 3015 * * * * * * * 10 0 * * * * * * 3364 0 0 F 11 * 4779 * * 2383 * 3208 * * * * * * * * 2529 * * * 1028 11 0 * * * * * * 3331 0 0 K 12 * 3679 3590 4195 * * * * 1338 * 5151 * * 3888 3085 3791 5078 3772 * * 12 54 * 4774 * * * * 3588 0 0 I 13 * * * * * * * 1584 * * * * * * * * * 585 * * 13 0 * * * * * 0 3541 0 1000 A 14 1632 * * * * * * * 1069 * * * * * 3003 5071 4436 * * * 14 0 * * * * * 0 3675 0 1000 D 15 * * 177 * * * * * * * * 3111 * * * * * * * * 15 0 * * * * * 0 3675 0 1000 L 16 4668 * * * 5071 * * 1041 * 2116 3332 * 3654 * * 4817 * * * * 16 0 * * * * 0 * 3675 0 1000 S 17 3477 * 5446 * * 2869 * * 2969 * * 5168 * * 4013 1338 2865 * * * 17 0 * * * * * * 3753 0 0 L 18 * * * 5357 * * * * 4605 593 5446 * * 2216 * 4912 * * * * 18 0 * * * * * * 3753 0 0 A 19 346 * 4050 * * * * * * * * * * * 4822 4122 * 4956 5168 * 19 61 * 4605 * * * * 3753 0 0 D 20 3612 * 1915 1559 * * 6095 * 3855 * * * 2392 * * * 4662 * * * 20 0 * * * * 0 * 3676 0 1000 F 21 4210 * 4956 3981 1525 * * * 5446 3818 * * 4912 3722 3853 3398 * * 3550 4306 21 0 * * * * * * 3753 0 0 G 22 * * * 5171 * 41 * * * * * * * * * * * * * * 22 0 * * * * * * 3773 0 0 R 23 * * * 5227 4798 * 3044 * 3128 3758 * * * 4366 858 * 5174 * * * 23 0 * * * * * * 3773 0 0 K 24 5004 * 5303 3234 * * 4227 4156 1559 4009 * * * 2826 2434 * * * * * 24 0 * * * * * * 3773 0 0 E 25 3637 * * 1444 * 5279 * * 2829 4329 * * * 3443 2227 5047 * * * * 25 38 * 5279 * * * * 3897 0 0 L 26 * * * * * * * 835 * 1694 4057 * * * * * 5774 5466 * 5084 26 0 * * * * * 0 3795 0 1000 R 27 2842 * 2729 1607 * * * 4959 3653 * * 3620 * * 3287 * 4062 * * 5255 27 0 * * * * * 0 3795 0 1000 I 28 * * * * * * * 2803 * 1815 * * * * * * * 5000 989 4744 28 0 * * * * * 0 3795 0 1000 A 29 289 * * * * * * * * * * * * * 4430 * 5456 3155 * * 29 0 * * * * * 0 3795 0 1000 E 30 4617 * * 1175 * 4230 * * 2534 5507 3802 * * * 2945 4354 * * 5805 * 30 0 * * * * * 0 3954 0 1000 H 31 3198 * 5174 4605 * * 3255 * * 3839 * 2334 * 2864 2938 3771 6037 3427 * * 31 0 * * * * * 0 4124 0 1000 E 32 * * 4415 873 3986 * 1974 * * * * 5333 * * * 4363 * * * 5963 32 0 * * * * * 0 4293 0 1000 M 33 4486 5271 * * 5006 * * * * * 422 * * * * 3493 * * * 3989 33 0 * * * * * 0 4329 0 1000 P 34 5064 * * * * * * * * * * * 179 5356 5312 6066 5484 * * * 34 76 * 4284 * * * 0 4383 0 1000 G 35 2671 * * * 3736 1615 * 3588 * 4291 * * * * * * * 1703 * * 35 0 * * * * * 0 4283 0 1516 L 36 * * * * * * 5428 * * 313 3011 * * * * * 5144 5698 * * 36 0 * * * * * 0 4283 0 1516 M 37 3007 * 5258 5144 * * 3736 3913 5840 4161 1954 3190 * 5630 2988 5944 4201 5509 * * 37 0 * * * * 0 * 4283 0 1516 S 38 1537 5802 5249 3695 * 4500 5080 * 5006 6254 * 4606 * 3343 4021 2568 5816 5135 * * 38 0 * * * * * * 4414 0 0 L 39 5224 5627 * * 4347 * * 3111 * 1471 3322 * * 3350 * 4587 2989 4016 * * 39 29 * 5638 * * * * 4414 0 0 R 40 5341 * 5854 3965 * * * 3482 5056 3199 5209 * * * 904 * 5053 4518 * 5045 40 0 * * * * * 0 4400 0 1000 R 41 2879 * 3185 1874 * * 4106 * 2847 * * 4546 * * 3436 3505 4034 * * * 41 0 * * * * * 0 4400 0 1000 E 42 3595 * 5189 1923 * * * * 4092 * 5257 * * 3793 1548 4159 5045 4614 * * 42 0 * * * * * 0 4400 0 1000 Y 43 3735 * * 4614 2171 * * 5161 * 3313 * 4589 * * * * * 5339 2934 1572 43 0 * * * * 0 * 4400 0 1000 A 44 2761 * * 2437 5501 2521 * * 5366 5482 * 6284 * 3973 3653 2398 3660 * * * 44 0 * * * * * * 4414 0 0 E 45 2166 * 5185 2616 * 3391 5147 5621 2864 * * 5547 3126 6075 6390 4324 5326 3884 * * 45 0 * * * * * * 4562 0 0 V 46 5547 * 3103 2100 * * * 5678 * 3661 * 5291 * * 5326 1716 2941 4464 * * 46 35 * 5379 * * * * 4562 0 0 Q 47 * * * * * 3942 * * 1612 5573 * * 4360 1937 2078 * 6150 5256 * * 47 0 * * * * * 0 4530 0 1000 P 48 * * 3383 * * * * 3984 * * * * 326 * * 5515 5536 * * * 48 32 * 5532 * * 0 * 4530 0 1000 L 49 * * * * 1987 * * * * 529 * * * * * * * 5310 * 5078 49 0 * * * * 0 * 4539 0 1000 K 50 1797 * 3387 3948 * 4638 * * 1387 * * * * * 5906 3402 5778 * * * 50 0 * * * * * * 4562 0 0 G 51 * * * 4638 * 97 * * * * * 5318 * * * * * * * * 51 0 * * * * * * 4562 0 0 A 52 1651 3889 5547 5882 5235 * 4559 3763 4199 2234 * * * * 4565 * * 3015 * * 52 0 * * * * * * 4562 0 0 R 53 * 4611 * * * 4042 5908 * 2320 * * 5904 * * 1204 3692 2931 5499 * * 53 0 * * * * * * 4562 0 0 I 54 * * * * * * * 684 * 2900 5985 * * * * * * 2135 * * 54 0 * * * * * * 4616 0 0 S 55 1711 * * * * 2312 * 5241 5561 3028 5829 * * * * 3343 4004 2791 * * 55 0 * * * * * * 4616 0 0 G 56 3540 4460 4264 * 5510 1586 3556 3788 * 3645 4248 * * * * 4737 5462 3168 * * 56 0 * * * * * * 4616 0 0 S 57 3468 1425 * * * 4372 4079 * * * * 3810 * * * 2200 5985 3000 * * 57 31 * 5561 * * * * 4616 0 0 L 58 6128 6203 * * * 4614 * 3072 * 1076 4030 * * * * 4317 3282 3013 * * 58 0 * * * * * 0 4591 0 1000 H 59 * * * * * * 483 5319 * * * * 2207 * * * * 4553 * * 59 0 * * * * * 0 4591 0 1000 M 60 * * * * * * * 3225 * 1244 2159 * * * * * * 2018 * * 60 0 * * * * * 0 4591 0 1000 T 61 * * 4467 1761 4246 * * * * 4614 * * * * * * 1069 4037 * 5135 61 0 * * * * * 0 4591 0 1000 V 62 2257 * * * * 4866 * 3252 4202 4467 * * 2844 5111 3623 4614 4669 2347 * 5268 62 0 * * * * * 0 4591 0 1000 Q 63 * * 4614 2468 * * * * 1555 * * 2815 * 1905 * * 5111 * * * 63 0 * * * * 0 * 4591 0 1000 T 64 6203 * * * * * * * * 4694 4460 * * * * 5299 251 4780 * * 64 0 * * * * * * 4616 0 0 A 65 635 5241 * * * 3207 * * * 3556 4242 * * * * 5510 * 4028 * * 65 36 5848 7130 4248 78 * * 4616 1000 0 V 66 3242 3797 * * * * 6171 5316 * 3481 * 4091 4475 * 5939 * 4334 1098 * 4129 66 0 * * * * * 0 4609 0 1000 L 67 * * * 5130 5759 * * * 2814 571 6030 * * 3501 * * * * 4887 * 67 0 * * * * * 0 4609 0 1000 I 68 2357 * * * * * * 1303 * 2285 5686 * * * * * * 3419 * 3622 68 0 * * * * * 0 4609 0 1000 E 69 2626 * * 1261 * * * 5202 4391 3645 4450 * * 4621 3060 5484 * * * 4743 69 0 * * * * * 0 4609 0 1000 T 70 2605 3980 * 5268 * 3922 4391 6030 5316 4704 5344 * * * * 4982 1065 5680 * * 70 0 * * * * * 0 4609 0 1000 L 71 * * * * 4478 * * 5572 * 174 * * * * * 4391 * * * * 71 0 * * * * * 0 4609 0 1000 T 72 2683 6166 * * * * 6030 4865 2790 3357 4621 4934 * * 4208 3837 2472 2635 * * 72 0 * * * * * 0 4609 0 1000 A 73 773 * 4068 3015 * * 6001 * 5009 4036 * 5918 * * 3752 5382 6795 * * * 73 0 * * * * * 0 4615 0 1000 L 74 1915 5040 * * * 2293 * * 5537 1376 * * * 4502 5382 * * * * 5295 74 37 * 5295 * * * 0 4615 0 1000 G 75 * * * * * 38 * * * * * 5282 * * * * * * * * 75 0 * * * * 930 1073 4557 0 1326 A 76 142 5382 * * * * * * * 4502 * * * * * * 5295 * * * 76 88 * 4081 * * * 0 4615 0 1000 E 77 5462 * 2686 1220 * * * * 3307 * * 3896 * 4955 2979 6127 4291 * * * 77 59 4634 * 2000 415 1060 942 4462 1000 1668 V 78 5080 4971 * * * * * 2636 * 2895 * * 6405 4476 * * 4665 870 * * 78 71 * 4381 * * * 0 4499 0 1203 R 79 2663 * * * 4657 * * 4636 * 5069 * * * 4569 1690 5263 3535 2201 * 4305 79 72 * 4364 * * 1432 668 4419 0 1899 W 80 4020 3558 * * 5567 5263 * 3579 * 2628 * * * * * * * 2263 1504 * 80 0 * * * * * 0 4329 0 2075 A 81 1556 2979 * * 5243 5026 * 4139 * * * * * * * 3359 2025 3714 * * 81 122 * 3625 * * * 0 4329 0 2075 S 82 3074 * * * * 1957 * * 3733 4818 * * 5289 * * 1648 3258 4834 * 5122 82 39 * 5236 * * 2338 318 4180 0 2941 C 83 * 1074 4465 * * 3486 * * * 5044 * * 5411 * * 1698 * * 5147 * 83 101 * 3887 * * 1537 610 4163 0 2903 N 84 * * 3944 5378 * 5095 * * * 5368 * 410 4103 * * * * * * 4427 84 0 * * * * 1314 742 4199 0 3105 I 85 4407 * 5140 * * 4944 5453 1575 * 5362 * * 1067 * * * * 4960 * * 85 0 * * * * 1150 864 4266 0 2495 F 86 5045 * 5285 * 1593 3558 5585 5154 * 2514 5111 5415 * * * 3892 4322 * * 2900 86 0 * * * * * 0 4333 0 1997 S 87 * * * 4216 * * * * 4581 * * * 4132 * * 487 3153 5534 * * 87 44 5045 * 1585 585 * 0 4333 1000 1997 T 88 3782 * * 5047 * * 5154 * * 4581 * * * * * 5124 519 3805 * 5111 88 0 * * * * * 0 4333 0 1997 Q 89 5673 * 3596 6959 5047 * 3161 * 5211 * * * * 616 3879 * * * * * 89 0 * * * * * 0 4333 0 1997 D 90 4581 * 563 5256 * 5585 * * * * * 3816 2613 * * * * * * * 90 0 * * * * * 0 4333 0 1997 H 91 5585 * 1312 2079 * 4560 2263 * * * * * * 5543 3890 * * * * * 91 206 * 2912 * * * 0 4333 0 1997 A 92 1993 * * * * * * 3044 * * * * * * * * 3200 947 * * 92 0 * * * * * 0 4196 0 2932 A 93 737 4009 * 4396 * * * 4853 * * * * * * * 5661 * 2084 * * 93 0 * * * * * 0 4196 0 2932 A 94 403 * * 4947 * 5044 * * * * * * * * 5355 3524 4853 4828 * * 94 0 * * * * * 0 4196 0 2932 A 95 854 4228 * * 4242 6043 4396 * * 4068 * * * 4947 4928 5866 * * 4079 3705 95 0 * * * * 3264 159 4196 0 2932 V 96 * * * * * * * 2853 * 443 * * * * * * * 2988 * * 96 459 * 1875 * * 2576 265 4220 0 2737 V 97 1528 * * * * * 4486 * 4342 * * * 4664 3954 * * * 1135 * * 97 627 * 1505 * * * 0 3938 0 3621 V 98 3887 * 3478 2632 * * * * 3006 * * 3950 * * 4598 2976 2927 2380 * * 98 274 * 2532 * * 4396 70 3619 0 4019 G 99 3803 * 4386 * 2971 2423 3364 * * 3370 * 2485 3865 * * 2993 * * * * 99 513 * 1741 * * 3224 163 3645 0 4073 P 100 2770 * 3309 * * 1586 3395 * * * * * 1903 * * 4134 * * * * 100 0 * * * * 3008 192 3123 0 4027 H 101 1475 * 4525 * * * 2418 3692 4064 * * * * 4408 * 3760 * 2722 * * 101 0 * * * * 5958 23 3223 0 3908 G 102 943 * 3439 * 2872 2502 * * * * * * * * * * * 3747 * * 102 70 * 4409 * * * 0 3250 0 3979 T 103 1630 * 3790 3353 * * * * * * 2899 * * * * * 2295 4836 4863 3326 103 155 * 3292 * * 6365 18 3337 0 4013 P 104 2109 * * * 3751 5152 * 2569 4591 * * 3872 3129 * * * 3209 2997 4653 * 104 165 * 3209 * * 4330 74 3250 0 4117 D 105 2505 4886 2469 2430 * 4081 * 2538 * * 3926 4015 * * * 5308 4660 * * * 105 58 * 4660 * * 1771 500 3243 0 4229 E 106 2574 * 2987 2665 * 4599 * 5926 3475 * * 4597 * 3649 2130 4292 * * * * 106 0 * * * * 1034 966 3868 0 3743 P 107 2272 * 2631 2865 * * * * 4522 4989 * 5675 3084 2936 3552 3925 * * * * 107 0 * * * * 2759 231 4247 0 3096 K 108 2854 * 3382 2913 * 5016 * * 2282 * * * 4959 2803 4021 * 6387 * 4765 3176 108 0 * * * * 1331 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0 2085 D 433 3808 * 4730 2088 * 6098 * * 2994 5098 * 5607 2244 5139 4472 4118 3902 5731 * 4713 433 28 5684 * 1585 585 1528 614 5868 1000 2129 N 434 3730 * 4557 5153 * 4888 4882 6684 3031 6920 * 3248 1497 5070 * 3462 5171 4713 * * 434 33 6158 6841 3000 193 939 1063 5887 1000 1563 E 435 2087 4853 4188 6709 * 1083 * 6333 4996 * * 3819 * * 5586 5283 4939 * * * 435 36 5360 * 3003 192 * 0 5914 1361 1664 V 436 6048 * * * * * * 2377 * 2394 * * 5209 * * * * 798 * * 436 0 * * * * 830 1193 5914 0 1664 Y 437 * * * 6182 * * 2112 3854 * 3683 * 2196 5984 3750 4981 * 5336 4087 * 2441 437 148 4166 4572 1267 774 * 0 5868 1913 1000 R 438 4544 * 5664 5482 6844 2856 * 5081 5383 2547 5885 3348 3092 * 4318 3183 5539 2949 * * 438 17 6420 * 2585 263 957 1044 5829 1000 2756 L 439 4307 * 6118 * * 6144 * 3713 * 1182 4556 5441 * 6217 * 5914 4112 1997 * * 439 0 * * * * 1026 974 5861 0 1544 P 440 6004 4381 4285 * * 3601 * 5634 * * * * 542 5876 * 4913 5886 * * 5127 440 56 4720 * 1854 467 * 0 5805 1471 1000 K 441 3087 * 4053 2705 * 3797 4201 6602 2438 * * 5114 4287 6324 3184 5307 * 3774 * 4425 441 98 5239 4674 2326 321 * 0 5799 1631 1000 H 442 3992 * 2941 1616 * * 3938 4264 3121 * 5599 * 5064 * 6079 4291 4100 3763 * * 442 0 * * * * * 0 5613 0 1673 L 443 * * 4698 * 5041 * * 1882 * 1711 3620 * 5055 4773 * 4170 5390 2978 * * 443 0 * * * * * 0 5574 0 1673 D 444 3671 4773 898 2437 * * * * 4266 * 5654 4009 * 5070 * * * * * * 444 40 5185 * 3170 170 * 0 5574 1000 1673 E 445 4615 * 3663 995 * * * 4632 4475 4870 * * 5770 3086 3911 4484 6385 * * * 445 28 5689 * 0 * * 0 5440 1000 1673 K 446 5341 * 3812 1817 6265 * * * 3412 3897 3355 3601 * 4386 4640 5583 3526 * * 3826 446 29 * 5673 * * * 0 5440 0 1673 V 447 3809 * * * 5961 * 5676 1645 * 3806 * 6323 5350 * 5494 * * 1176 * * 447 158 3884 4786 1227 804 1416 678 5430 1850 2273 A 448 336 * 6241 4591 * 5006 * 5430 * * * * 4678 * * 4551 * 5890 * * 448 88 4082 * 0 * 1708 527 5178 1464 2245 R 449 3108 * * 2804 * 5696 * * * 3805 6060 * * 4845 1899 3079 * * 3347 3113 449 0 * * * * 952 1050 5300 0 1718 I 450 3775 * 5941 5793 * * * 2707 * 941 5066 * * * 5592 5241 5972 3475 * 4812 450 30 5584 * 1000 1000 * 0 5292 1000 1000 H 451 4070 * 4127 3280 5226 * 1944 5066 1689 * 4136 * 4639 * * 5719 * * 4725 * 451 73 4341 * 2130 374 * 0 5292 1809 1000 V 452 6164 3734 * * * * * 5762 * 344 4181 * * * * * * 4337 * * 452 230 2761 * 0 * * 0 5233 2900 1000 E 453 3160 * 4051 2384 * 2801 * * 2595 * * 4260 3518 3372 4243 5655 * 5757 * * 453 70 4409 * 0 * * 0 5233 1531 1000 A 454 2093 * 4656 5571 * 4697 4527 * 2132 * * 4363 * 6328 5228 2848 2703 6093 * * 454 0 * * * * * 0 5188 0 1000 L 455 4164 * * 6046 3299 * * 5571 * 961 3031 * * 5895 5153 4219 * 4930 * 4674 455 0 * * * * * 0 5188 0 1000 G 456 3134 * 4591 * * 650 * * * 5571 * 2423 * * * * * * * * 456 0 * * * * * 0 5188 0 1000 G 457 2302 * * * * 2625 * 2009 * * 5640 * * * 5254 4563 * 1746 * * 457 0 * * * * 0 * 5379 0 1000 H 458 3485 * 5892 4598 4581 3010 4455 5270 2901 2997 * 5778 * 3836 2918 5568 4330 3950 * * 458 0 * * * 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4412 * 4177 3243 4698 5206 5666 * * 468 0 * * * * * * 5436 0 0 Y 469 * * * 3660 3205 * 4992 * 4518 4737 * 4161 * 5140 * 4532 3872 * * 988 469 0 * * * * * * 4996 0 0 L 470 3318 * * * * * * 2119 * 885 4106 * * * * * * 3840 * * 470 0 * * * * * * 4996 0 0 G 471 * * 4925 5506 * 911 5200 * * * * 2463 * * * 3501 3104 * * * 471 0 * * * * * * 4907 0 0 V 472 * * * * * * * 1515 * 2323 2991 * * * * * * 1967 * 3862 472 0 * * * * * * 4786 0 0 D 473 * * 1909 3127 * 5464 5072 * 3219 * * 4604 2571 5102 3078 4433 4153 * * * 473 182 4021 4137 1000 1000 * * 4702 1000 0 V 474 5640 5502 * * * * * 2425 3355 * 3911 * 4703 * * * 4512 1294 * 3090 474 0 * * * * * 0 4871 0 1000 E 475 2281 * 3104 2174 * * * * 3445 * * 3863 * 4244 2362 4370 * * * * 475 0 * * * * * 0 4516 0 1000 G 476 * * * * * 124 * * * * * * * * 4321 4955 * * * * 476 0 * * * * * 0 4420 0 1000 P 477 * * * 3111 * * * * * * * * 389 * * 3050 * * * * 477 0 * * * * * 0 3415 0 1000 Y 478 * * * * 1168 * * * * * * * * * * * * 3167 * 1173 478 0 * * * * 0 * 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