HHsearch 1.5 NAME c2lftA_ FAM FILE c2lftA_ COM /bmm/www/servers/phyre2/HH/hhmake -i c2lftA_.a3m DATE Thu Jan 10 02:36:39 2013 LENG 142 match states, 142 columns in multiple alignment FILT 10 out of 14 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 2.1 EVD 0.4254 -0.0836 SEQ >ss_dssp CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCSCSSCCEEEECCCCCCCSSSHHHHHHHHHHGGGSCCEEECCCCTTCSSTTTHHHHHHHHHHHHHHH HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTC >sa_dssp EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEDECEEDEDDDECECCEBEDEEEECBECAEECCECABDCABDDBCEEEECEEDABCDAADBBBCCCCE ECDEEECEBDECAEEABCDAACCBADECBDECBEDDEEEEEE >ss_pred CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCC CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC >ss_conf 9888763114688765005888877544567777666655542047888777861577889899875395017747532334777888886301100014 544455652224679999999999999999999998750479 >Consensus gxxxxxxxqxnkpxkskxxxKxxaxAAxxGAvxGmaxgYxlGrxxxrpxfxFxnPxEexyynxxmxrypxxvxYrpxxxxxsxxxFvxdCxNxTxxqxsx xpsxkgxdxxexDtvxxxxiIeqMCvxqYxxysxxxxqrxSx >c2lftA_ GQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTV TTTTKGENFTETDVKMMERVVEQMCITQYKRESQAYYQRGSS >UniRef50_Q5I4J0(288-438:506) Prion protein n=8 Tax=Percomorpha RepID=Q5I4J0_LATJA E=5e-35 s/c=0.98 id=32% cov=88% -------------PKSTGFAKKAVMAAGVGAVAGMAIGYGLGR-FPRPHFNFRNPEEEQYYNNFMYRrygsqstdekdYGRDYVYKPPPRAESYENFMGR CMNKTDllkDQGSSSPSLKGGDEDNDDTVGIEEIgypalIEQLksrpCVEQYMVYSERFLQ---- >UniRef50_Q5K0E1(363-488:606) Prion protein 1 n=5 Tax=Danio rerio RepID=Q5K0E1_DANRE E=5e-14 s/c=0.62 id=36% cov=41% ---------YNPSAKSKGFGKKAVVAAGVGAMAGMAIGYGIGN-FQRPNFQFRSPQEERYYNNHMYQ--------------------------------- ------------------------------------------ >UniRef50_A2BDK1(295-386:557) Prion protein 2A PrP2A n=2 Tax=Gasterosteus aculeatus RepID=A2BDK1_GASAC E=1e-13 s/c=0.84 id=43% cov=30% -------------------------AAGGGALVGMALGYGLGR-FPRPPFSFHNPQEEHYYNHYMYR--------------------------------- ------------------------------------------ >UniRef50_Q50J88(289-351:567) PrP2 protein n=11 Tax=Danio rerio RepID=Q50J88_DANRE E=3e-06 s/c=0.84 id=45% cov=37% --------------KSKGFGKQAIIAAGAGAVAGMALGYGLGS-FPRPRFHFHNPQEEYYYNHYMYR--------------------------------- ------------------------------------------ >UniRef50_A2BDK3(227-375:409) Prion protein 1 PrP1 n=1 Tax=Oryzias latipes RepID=A2BDK3_ORYLA E=1e-24 s/c=0.77 id=27% cov=90% -------------PRSTGFAKKAMMAAGVGALAGMAVGYGLGR-FPRPHFNFRNPEEESYYNNYMYRrygkestdekdYGRDYVYKIPPRAESYEKFMAR CMNETDNgQASRSPApVSGVDTEEDDTVSIQEIgypalIEQMksrrCVEKYMIYSEQFLESRS- >UniRef50_Q801J8(356-451:605) Prion protein n=3 Tax=Euteleostei RepID=Q801J8_SALSA E=2e-17 s/c=0.94 id=33% cov=37% -------------TQSKGFAKKAFMAAGVGALAGMAVGYGLGR-FPRPHFNFRNPQEEQSYNNYM----------------------------------- ------------------------------------------ >UniRef50_Q5VJ83(195-282:425) Prion protein 2 n=4 Tax=Tetraodontidae RepID=Q5VJ83_TAKRU E=5e-14 s/c=0.89 id=41% cov=31% -----------------------ARAASGGAVAKMAVDYGLGR-FPRPPFQFQSPEEEYYYNHYMYR--------------------------------- ------------------------------------------ >UniRef50_Q6GLY6(54-234:235) Major prion protein n=6 Tax=Xenopus RepID=Q6GLY6_XENLA E=4e-52 s/c=0.94 id=41% cov=91% GGSNFNNKQW-KPPKSKTNMKAVAVGAAAGAIGG----YMLGNAVGRMNHHFDNPMESRYYNDYYNQMPDRV-YRPMyrsEEYVSEDRFVTDCYNMSVTE YIIKPSegKNGSDVNQLDTVVKSKIIREMCITEYR--------RGSG >UniRef50_P27177(51-247:273) Major prion protein homolog n=19 Tax=Sauropsida RepID=PRIO_CHICK E=3e-42 s/c=1.09 id=51% cov=94% GQgynpssGGSYHNQ--KPWKpPKTNFKHVAGAAAAGAVVGGLGGYAMGRVMSGMNYHFDSPDEYRWWSENSARYPNRVYYRDYSSPVPQDVFVADCFNI TVTEYSIGPAAKkntseavaAANQTEVEMenKVVTKVIREMCVQQYREYRLA------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * G 1 * * * * * 0 * * * * * * * * * * * * * * 1 0 * * * * * * 1696 0 0 Q 2 * * * * * 1642 * * * * * * * 557 * * * * * * 2 577 1601 * 2585 263 * * 1696 1000 0 G 3 * * * * * 557 * * * * * * * * * 1642 * * * * 3 0 * * * * * * 1696 0 0 G 4 * * * * * 557 * * * * * 1642 * * * * * * * * 4 0 * * * * * * 1696 0 0 G 5 * * * * 1642 1515 * * * * * * * * * 1601 * * * * 5 0 * * * * * * 1696 0 0 T 6 * * * * * * * * * * * 1642 * * * * 1515 * * 1601 6 0 * * * * * * 1696 0 0 H 7 * * * * * * 557 * * * * 1642 * * * * * * * * 7 0 * * * * * * 1696 0 0 S 8 * * * * * * * * 1642 * * 1601 * * * 1515 * * * * 8 0 * * * * * * 1696 0 0 Q 9 * * * * * * * * * * * * * 0 * * * * * * 9 577 * 1601 * * * * 1696 0 0 W 10 * * * * * * * * * * * * * * * * * * 645 1471 10 497 * 1778 * * * 0 1742 0 1000 N 11 * * * * * * * * * * * 0 * * * * * * * * 11 0 * * * * 0 * 1537 0 1427 K 12 * * * * * * * * 527 * * * 1708 * * * * * * * 12 0 * * * * * * 1906 0 0 P 13 * * * * * * * * * * * * 527 * * 1708 * * * * 13 0 * * * * * * 1906 0 0 S 14 2943 * * * * * * * * * * * 1380 * * 2535 3066 * 2368 * 14 0 * * * * * * 2096 0 0 K 15 * * * * * * * * 326 * * * * 3314 3301 * * * * * 15 290 2459 * 0 * * * 2109 1000 0 P 16 * * * * * * * * * * * * 1575 * * 590 * * * * 16 0 * * * * * * 2109 0 0 K 17 * * * * * * * * 314 * * * * * * * 2355 * * * 17 0 * * * * * * 2109 0 0 T 18 * * * * * 945 * * * * * * * * * * 1057 * * * 18 0 * * * * * * 2109 0 0 N 19 * * * * 945 * * * * * * 1057 * * * * * * * * 19 0 * * * * * * 2109 0 0 M 20 1756 * * * 2459 2162 * * * * 1743 * * * * * * * * * 20 0 * * * * * * 2109 0 0 K 21 * * * * * * * * 0 * * * * * * * * * * * 21 0 * * * * * * 2109 0 0 H 22 2788 * * * * * 1575 * 1298 * * * * 3148 * * * * * * 22 0 * * * * * * 2109 0 0 M 23 945 * * * * * * * * * 2700 * * * * * * 1614 * * 23 0 * * * * * * 2109 0 0 A 24 813 * * * 3585 * * 3445 * * 3653 * * * * * * 2505 * * 24 0 * * * * * * 2178 0 0 G 25 * * * * * 1668 * 3445 * * 2053 * * * 3090 * * 2088 * * 25 0 * * * * * * 2178 0 0 A 26 215 * * * * 2856 * * * * * * * * * * * * * * 26 0 * * * * * * 2199 0 0 A 27 0 * * * * * * * * * * * * * * * * * * * 27 0 * * * * * * 2199 0 0 A 28 1174 * * * * 1134 * * * * * * * * * 3305 * * * * 28 0 * * * * * * 2199 0 0 A 29 943 * * * * 2516 * * * * * * * * * * * 1713 * * 29 0 * * * * * * 2199 0 0 G 30 * * * * * 0 * * * * * * * * * * * * * * 30 0 * * * * * * 2199 0 0 A 31 0 * * * * * * * * * * * * * * * * * * * 31 0 * * * * * * 2199 0 0 V 32 * * * * * * * 2856 * 2220 3414 * * * * * * 854 * * 32 0 * * * * * * 2199 0 0 V 33 1049 * * * * 2856 * * * * * * * * * * * 1401 * * 33 0 * * * * * * 2199 0 0 G 34 * * * * * 154 * * 3305 * * * * * * * * * * * 34 215 * 2856 * * * * 2199 0 0 G 35 * * * * * 1422 * * * * 674 * * * * * * * * * 35 0 * * * * * 0 2004 0 1000 L 36 674 * * * * * * * * 1422 * * * * * * * * * * 36 0 * * * * * 0 2004 0 1000 G 37 * * * * * 1422 * 2417 * 2549 * * * * * * * 1896 * * 37 0 * * * * * 0 2004 0 1000 G 38 * * 3171 * * 170 * * * * * * * * * * * * * * 38 0 * * * * 0 * 2004 0 1000 Y 39 * * * * * * * * * * * * * * * * * * * 0 39 0 * * * * * * 2199 0 0 M 40 2553 * * * * 845 * * * * 1875 * * * * * * * * * 40 0 * * * * * * 2199 0 0 L 41 * * * * * * * 3414 * 443 2553 * * * * * * * * * 41 0 * * * * * * 2199 0 0 G 42 * * * * * 0 * * * * * * * * * * * * * * 42 0 * * * * * * 2199 0 0 S 43 * * * * * * * * * * * 2108 * * 846 2241 * * * * 43 1174 * 845 * * * * 2199 0 0 A 44 577 * * * * * * * * * * * * * * * * 1601 * * 44 0 * * * * 0 * 1696 0 1467 M 45 * * * * 845 * * * * * 1713 * * * * * * 2856 * * 45 0 * * * * * * 2199 0 0 S 46 * * * * * 2856 * * * * * * 1111 3414 * 1713 * * * * 46 0 * * * * * * 2199 0 0 R 47 * * * * * 2553 * * * * * * * * 270 * * * * * 47 0 * * * * * * 2199 0 0 P 48 * * * * * * * * * * 1696 * 532 * * * * * * * 48 0 * * * * * * 2199 0 0 I 49 * * * * * * 2243 2894 * * * 1313 2516 * 3698 * * * * * 49 0 * * * * * * 2199 0 0 I 50 * * * * 845 * 2856 2894 * * * * * * * * * * * 2553 50 0 * * * * * * 2199 0 0 H 51 * * * * * * 943 * * * * 2243 * 2359 * 3764 * * * * 51 0 * * * * * * 2199 0 0 F 52 * * * * 0 * * * * * * * * * * * * * * * 52 0 * * * * * * 2199 0 0 G 53 * * 1696 * * 2894 2730 * * * * * * 3305 1713 * * * * * 53 0 * * * * * * 2199 0 0 S 54 * * * * * * * * * * * 1000 * * * 1000 * * * * 54 0 * * * * * * 2199 0 0 D 55 * * 2894 * * * * * * * * * 208 * * * * * * * 55 0 * * * * * * 2199 0 0 Y 56 * * 2553 2052 * * * * * * 2856 * * 1663 * * * * * 2894 56 0 * * * * * * 2199 0 0 E 57 * * * 0 * * * * * * * * * * * * * * * * 57 0 * * * * * * 2199 0 0 D 58 * * 2894 845 * * * * * * * * * * * 2856 * * * 2553 58 0 * * * * * * 2199 0 0 R 59 * * * * * * 3764 * * * * * * 2822 897 3841 * * * 2488 59 0 * * * * * * 2199 0 0 Y 60 * * * * * * * * * * * * * * * 3812 * * 2553 399 60 0 * * * * * * 2199 0 0 Y 61 * * * * * * * * * * * * * * * * * * 2553 270 61 0 * * * * * * 2199 0 0 R 62 * * * * * * * * * * * 525 * * 2894 2553 * * * * 62 0 * * * * * * 2199 0 0 E 63 * * 2856 1713 * * 1989 * * * * 1713 * * * * * * * * 63 0 * * * * * * 2199 0 0 N 64 * * * * 3833 * 3414 * * * * 1713 * * * * * * * 913 64 0 * * * * * * 2199 0 0 M 65 * * * * * * * * * * 532 * * * * 2553 * * * 2856 65 0 * * * * * * 2199 0 0 H 66 2460 * * * * * 2825 * * * * 2785 * * * * * * * 910 66 0 * * * * * * 2145 0 0 R 67 * * * * * * * * * * * * * 2022 408 * * * * * 67 426 1967 * 3459 138 * * 2145 1163 0 Y 68 * * * * * * * * * * 2361 * * * * * * * * 312 68 0 * * * * * * 2246 0 0 P 69 * * * * * 1428 * * * * * * 671 * * * * * * * 69 0 * * * * * * 2246 0 0 N 70 * * 2361 * * * * * * * * 1206 * * 1428 * * * * * 70 0 * * * * * * 2246 0 0 Q 71 * * 1428 * * * * * * * * * * 2222 1273 * * * * * 71 0 * * * * * * 2246 0 0 V 72 * * * * * * * * * * * * * * * * * 671 * 1428 72 312 * 2361 * * * * 2246 0 0 Y 73 * * * * * * * * * * * * * * * * * 1158 * 857 73 0 * * * * 0 * 2056 0 1000 Y 74 * * * * * * * * * * * * * * * * * * * 0 74 0 * * * * * * 2246 0 0 R 75 * * * * * * * * 1428 * * * * * 671 * * * * * 75 0 * * * * * * 2246 0 0 P 76 * * 2190 * * * * 2408 * * * * 755 * * * * * * * 76 0 * * * * * * 2246 0 0 M 77 * * * * * * * * * * 1290 * 1428 * * * * * * 2190 77 312 2361 * 1585 585 * * 2246 1000 0 D 78 * * 2222 2361 * * * * * * * * 1428 * * 2190 * * * * 78 0 * * * * * * 2246 0 0 E 79 * * * 1290 * * * * * * * * * * 1428 2190 * * * * 79 0 * * * * * * 2246 0 0 Y 80 1428 * * * * * * * * * * * 2190 * * * * * * 1290 80 0 * * * * * * 2246 0 0 S 81 * * * 1428 * * * * * * * * * * * 2222 * 1273 * * 81 0 * * * * * * 2246 0 0 N 82 * * * * * * * * * * * 2222 2190 * * 820 * * * * 82 0 * * * * * * 2246 0 0 Q 83 * * * 2361 * * * * * * * * * 1206 * * * * * 1428 83 0 * * * * * * 2246 0 0 N 84 * * 1273 1428 * * * * * * * 2222 * * * * * * * * 84 0 * * * * * * 2246 0 0 N 85 * * * * * * * * 2408 * * 1330 * * 2361 * * 2190 * * 85 0 * * * * * * 2246 0 0 F 86 * * * * 0 * * * * * * * * * * * * * * * 86 0 * * * * * * 2246 0 0 V 87 * * * * * * * * * * 1428 * * * * * * 671 * * 87 0 * * * * * * 2246 0 0 H 88 1295 * * * * 2448 2222 * * * * * * * * * 2361 * * * 88 0 * * * * * * 2246 0 0 D 89 * * 671 * * * * * * * * * * * 1428 * * * * * 89 0 * * * * * * 2246 0 0 C 90 * 0 * * * * * * * * * * * * * * * * * * 90 0 * * * * * * 2246 0 0 V 91 * * * * 2190 * * * * * 1428 * * * * * * 2222 * 2361 91 0 * * * * * * 2246 0 0 N 92 * * * * * * * * * * * 0 * * * * * * * * 92 0 * * * * * * 2246 0 0 I 93 * * * 2408 * * * 1206 2448 * 2361 * * * * * * * * * 93 0 * * * * * * 2246 0 0 T 94 * * * * * * * * * * * * * * * 2361 312 * * * 94 0 * * * * * * 2246 0 0 I 95 * * 1428 * * * * 2222 * * * * * * * * * 1273 * * 95 292 2448 * 1585 585 * * 2246 1000 0 K 96 * * 2448 * * * * * 2222 * * 2408 * * * * 1273 * * * 96 301 2408 * 0 * * * 2246 1000 0 Q 97 * * * 1273 * * * * * * * * * 771 * * * * * * 97 0 * * * * * * 2246 0 0 H 98 2408 * * * * 2448 2222 * * * * * * * * * * * * 1273 98 0 * * * * * * 2246 0 0 T 99 * * * * * * * 2361 * * * * * * * 759 2222 * * * 99 0 * * * * * * 2246 0 0 V 100 * * * * * * * 1273 * * * * * * 2408 2448 * 2222 * * 100 0 * * * * * * 2246 0 0 T 101 * * * * * 2190 * * 2361 * * * * * * 1428 2222 * * * 101 0 * * * * * * 2246 0 0 T 102 * * * * * * * * * * * * 348 * * * 2222 * * * 102 0 * * * * * * 2246 0 0 T 103 1295 * * * * * * * * * * * * * * 1404 2222 * * * 103 697 1384 * 650 1464 * * 2246 1517 0 T 104 2190 * * * * * * * 2361 2448 * * * * * * 2222 2408 * * 104 0 * * * * * * 2246 0 0 K 105 * * * * * * * * 697 * * 2361 * * * 2408 * * * * 105 357 2190 * 3000 193 * * 2246 1000 0 G 106 2190 * * * * 357 * * * * * * * * * * * * * * 106 0 * * * * * * 2246 0 0 E 107 2190 * * 2222 * 2448 * * * * * * * * * 2361 * 2408 * * 107 0 * * * * * * 2246 0 0 N 108 * * 820 * * * * * * * * 1206 * * * * * * * * 108 0 * * * * * * 2246 0 0 F 109 * * * 2448 2222 * * * * * * * * 2190 * * 2408 2361 * * 109 0 * * * * * * 2246 0 0 T 110 * * 2448 2408 * * * * * * * 2361 * * * * 1206 * * * 110 0 * * * * * * 2246 0 0 E 111 * * * 685 * * * * * * * 2448 * 2361 * * * * * * 111 0 * * * * * * 2246 0 0 T 112 * * 1428 * * * * * * 2361 * * * * * * 2222 2190 * * 112 0 * * * * * * 2246 0 0 D 113 * * 357 2190 * * * * * * * * * * * * * * * * 113 0 * * * * * * 2246 0 0 V 114 * * * * * * * * * * 2190 * * * * * 820 2222 * * 114 357 2190 * 1000 1000 * * 2246 1000 0 K 115 * * * * * * * * 1206 * * * * * * * * 820 * * 115 0 * * * * * * 2246 0 0 M 116 * * * * * 2448 * * * * 2222 * * * * 2408 * 1273 * * 116 0 * * * * * * 2246 0 0 M 117 * * * * * * * 1428 2361 * 2222 * * * * * * 2190 * * 117 0 * * * * * * 2246 0 0 E 118 * * * 1330 * * * * * * * * * 2408 * 2361 2190 * * * 118 0 * * * * * * 2246 0 0 R 119 * * * 1428 * * * * 1273 * * * * * 2222 * * * * * 119 0 * * * * * * 2246 0 0 V 120 * * * * * * * 820 * * * * * * * * * 1206 * * 120 671 1428 * 2322 322 * * 2246 1163 0 V 121 * * * * * * * 348 * * * * * * * * * 2222 * * 121 0 * * * * * * 2246 0 0 E 122 * * * 771 * * * * * * * * * * 1273 * * * * * 122 0 * * * * * * 2246 0 0 Q 123 * * * 1273 * * * * * * * * * 771 * * * * * * 123 0 * * * * * * 2246 0 0 M 124 * * * * * * * * * 2448 292 * * * * * * * * * 124 671 1428 * 2000 415 * * 2246 1163 0 C 125 * 0 * * * * * * * * * * * * * * * * * * 125 0 * * * * * * 2246 0 0 I 126 * * * * * * * 1290 * * * * * * * * * 759 * * 126 0 * * * * * * 2246 0 0 T 127 * * * 1428 * * * * * * * * * 2190 * * 1290 * * * 127 0 * * * * * * 2246 0 0 Q 128 * * * 2361 * * * * 2408 * * * * 697 * * * * * * 128 0 * * * * * * 2246 0 0 Y 129 * * * * * * * * * * * * * * * * * * * 0 129 0 * * * * * * 2246 0 0 K 130 * * * * * * * * 2222 * 1428 * * * 1273 * * * * * 130 312 * 2361 * * * * 2246 0 0 R 131 * * * 1819 * * * 2136 * * * * * * 1897 * * 2180 * * 131 0 * * * * * 0 2056 0 1000 E 132 * * * 1897 * * * * * * * * * * * * * * * 451 132 0 * * * * * 0 2056 0 1000 S 133 * * * * * * * * * * * * * * 1819 481 * * * * 133 0 * * * * * 0 2056 0 1000 Q 134 * * * 1158 * * * * * 1819 * * * 1897 * * * * * * 134 0 * * * * * 0 2056 0 1000 A 135 857 * * * * * * * * * * * * 2136 2180 * * * * * 135 0 * * * * * 0 2056 0 1000 Y 136 * * * * 783 * * * * * * * * * * * * * * 1256 136 0 * * * * * 0 1732 0 1000 Y 137 * * * * * * * * * 783 * * * * * * * * * 1256 137 0 * * * * * 0 1732 0 1000 Q 138 * * * 1753 * * * * * * * * * 508 * * * * * * 138 0 * * * * 0 * 1732 0 1000 R 139 * * * * * * * * * * * * * * 653 1458 * * * * 139 0 * * * * * * 1956 0 0 G 140 * * * * * 653 * * * * * * * * 1458 * * * * * 140 0 * * * * * * 1956 0 0 S 141 * * * * * * * * * * * * * * * 0 * * * * 141 0 * * * * * * 1956 0 0 S 142 * * * * * 1150 * * * * * * * * * 864 * * * * 142 0 * * 0 * * * 1438 0 0 //