|   |
357 | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | V | D | A | A | L | A | A | A | Q | T | N | A | A | A | K | V | D | I | L | G | V | D | F | D | N | T | T | M | L | Q | M | V | E | N | I | K | T | F | F | A | N | Q | S | T | N | N | L | F | I | V | T | A | N | P | E | I | V | N | Y |
Query Conservation |   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |
|   |
|   |
|
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |
|   |   |   |   | . | . |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
| . | . | . |
|
|
|   |   |   |   |   |   |   |   |
Template Sequence |   |
R | X | G | E | G | V | V | Q | A | G | K | E | F | N | L | N | A | S | Q | V | G | . |
. |
P | S | S | T | D | A | P | Q | Q | V | K | I | I | E | D | L | I | A | R | K | V | D | A | . |
. |
. |
I | T | I | V | P | N | D | A | N | V | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
| . | . |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  | . | . | . |  |  |  |
|
| S |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
. | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | |
|
|
. | 90 | . | . | . | . | . | . | . | . | . |
  |
  |   |
417 | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | T | H | Q | A | Y | L | E | L | I | N | Q | A | S | Y | I | V | A | D | G | T | G | V | V | K | A | S | H | R | L | K | Q | P | L | A | H | R | I | P | G | I | E | L | M | D | E | C | L | K | I | A | H | V | N | H | Q | K | V | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | . |
. |
. |
P | V | F | K | K | A | R | D | A | G | I | V | V | L | T | N | E | S | P | G | Q | P | S | A | N | W | D | V | E | I | I | D | N | E | K | F | A | A | E | Y | V | E | H | X | A | K | R | X | G | G | K | G | G | Y | V | I |
Template Known Secondary structure |   |
 | . | . | . |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  | S |
| T | T |
| T | T |
| S |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
100 | |
|
|
. | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . |
  |
  |   |
477 | . | . | 480 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | |
|
. | . | . | . | . | . | 510 | . | . | . | |
. | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | G | A | T | N | E | V | V | E | A | . |
. |
. |
. |
. |
A | Q | Y | A | L | Q | Q | R | Y | P | N | I | S | F | A | H | . |
. |
H | H | G | Y | I | D | L | E | D | E | . |
T | V | V | K | R | I | K | L | F | K | P | D | Y | I | F |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
Template Sequence |   |
Y | V | G | S | L | T | V | P | Q | H | N | L | W | A | D | L | L | V | K | Y | Q | K | E | H | Y | P | D | X | H | E | V | T | R | R | X | P | V | A | E | S | V | D | D | S | R | R | T | T | L | D | L | X | K | T | Y | P | D | L | K | A |
Template Known Secondary structure |   |
 |
| S |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  | S | S | S |
| B | S |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
157 | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
  |
  |   |
529 | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | |
|
|
. | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | G | M | G | F | P | K | Q | E | E | W | I | M | T | H | E | N | Q | F | E | . |
. |
. |
S | T | V | M | M | G | V | G | G | S | L | E | V | F | . |
. |
. |
. |
. |
. |
. |
. |
A | G | A | K | K | R | A | P | Y | I | F | R | K | L | N |
Query Conservation |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   | . | . | . |   |   |   |   |   |   |
|
|   |   |   |
|   |   | . | . | . | . | . | . | . | . |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |
Template Sequence |   |
V | V | S | F | G | S | N | G | P | I | G | A | G | R | A | V | K | E | K | R | A | K | N | K | V | A | V | Y | G | X | X | I | P | S | Q | A | A | S | L | I | K | S | G | D | I | T | E | G | I | T | Y | D | P | A | T | A | G | Y | A | L |
Template Known Secondary structure |   |
 |  |  | S | S | T | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | T |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  | T | S | S |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
  |
  |   |
578 | . | 580 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | E | W | I | Y | R | A | L | I |
Query Conservation |   |
|
|
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |
Template Sequence |   |
A | A | V | A | S | T | L | L | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
  |   |
277 | . | . | 280 | . | . | . | . | . |
  |