Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ9NHC3
DateSat Apr 13 12:56:47 BST 2013
Unique Job ID4dd35388f6c1116d

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:74.958 Y:56.516 Z:45.857
Model (left) based on template c2lqnA_
Top template information
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
Confidence and coverage
Confidence:100.0% Coverage: 96%
267 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTTNGFDPFEWRSFYFPGMSREEAHKLLGEPQVSIGTFLMRDSSRPGEYSLTVREADEGN
Secondary structure 






































SS confidence 



























































Disorder  ???????????



?











????











??








?????
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   .........70.........80.........90.........100.........110.........120
Sequence  AVCHYLIERGEPKEDGTAAAGVKIANQSFPDIPALLNHFKMRVLTEASLLAAYKKPIIEV
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Disorder  ??
??

?????????






???










???????????????????



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   .........130.........140.........150.........160.........170.........180
Sequence  VVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNALGTTGLVPANYVQIQMEFHND
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Disorder 










???
?













?
























???
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   .........190.........200.........210.........220.........230.........240
Sequence  RTSKGASQSSIGSSGGGAERFSSASTSSDNIELQPRLPAKAKVTFDRVPNAYDPTQLRVK
Secondary structure 



















































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Disorder  ?
???????????????????????????

?

?














?
????



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   .........250.........260.........270.........
Sequence  KGQTVLVTQKMSNGMYKAELDGQIGSVPHTYLRFTAVSE
Secondary structure 














SS confidence 






































Disorder 

































?????
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Confidence Key
High(9)                    Low (0)
?Disordered ( 38%)
Alpha helix ( 3%)
Beta strand ( 30%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2lqn chain A

3D model

Region: 1 - 279
Aligned: 267
Modelled: 272
Confidence: 100.0%
Identity: 31%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2eyz chain A

3D model

Region: 1 - 279
Aligned: 273
Modelled: 277
Confidence: 100.0%
Identity: 33%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 3qwx chain X

3D model

Region: 4 - 173
Aligned: 170
Modelled: 170
Confidence: 100.0%
Identity: 100%
PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174

Phyre2

PDB 3qwy chain A

3D model

Region: 5 - 173
Aligned: 169
Modelled: 169
Confidence: 100.0%
Identity: 100%
PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2

Phyre2

PDB 2eyy chain A

3D model

Region: 1 - 183
Aligned: 177
Modelled: 183
Confidence: 100.0%
Identity: 37%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i

Phyre2

PDB 2dvj chain A

3D model

Region: 1 - 211
Aligned: 205
Modelled: 211
Confidence: 100.0%
Identity: 33%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii

Phyre2

PDB 2l3s chain A

3D model

Region: 119 - 276
Aligned: 158
Modelled: 158
Confidence: 100.0%
Identity: 29%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 1gri chain A

3D model

Region: 120 - 277
Aligned: 152
Modelled: 158
Confidence: 100.0%
Identity: 22%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 1ng2 chain A

3D model

Region: 117 - 278
Aligned: 130
Modelled: 131
Confidence: 100.0%
Identity: 17%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2

PDB 1ov3 chain A

3D model

Region: 110 - 273
Aligned: 132
Modelled: 133
Confidence: 100.0%
Identity: 17%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 2eo3 chain A

3D model

Region: 1 - 115
Aligned: 103
Modelled: 115
Confidence: 99.9%
Identity: 36%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein

Phyre2

PDB 2oq1 chain A domain 1

3D model

Region: 7 - 117
Aligned: 99
Modelled: 111
Confidence: 99.9%
Identity: 24%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2y3a chain B

3D model

Region: 1 - 117
Aligned: 106
Modelled: 117
Confidence: 99.9%
Identity: 25%
PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941

Phyre2

PDB 2oq1 chain A domain 2

3D model

Region: 8 - 119
Aligned: 100
Modelled: 112
Confidence: 99.9%
Identity: 25%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2eyv chain A domain 1

3D model

Region: 13 - 115
Aligned: 98
Modelled: 103
Confidence: 99.9%
Identity: 38%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2gsb chain A

3D model

Region: 2 - 120
Aligned: 108
Modelled: 119
Confidence: 99.9%
Identity: 22%
PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1

Phyre2

PDB 2oq1 chain A

3D model

Region: 7 - 117
Aligned: 102
Modelled: 111
Confidence: 99.9%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2

PDB 2b3o chain A

3D model

Region: 7 - 134
Aligned: 120
Modelled: 128
Confidence: 99.9%
Identity: 22%
PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1

Phyre2

PDB 1csy chain A

3D model

Region: 4 - 119
Aligned: 107
Modelled: 115
Confidence: 99.9%
Identity: 20%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1a81 chain E domain 2

3D model

Region: 8 - 115
Aligned: 99
Modelled: 108
Confidence: 99.9%
Identity: 22%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
1

c2lqnA_
2

c2eyzA_
3

c3qwxX_
4

c3qwyA_
5

c2eyyA_
6

c2dvjA_
7

c2l3sA_
8

c1griA_
9

c1ng2A_
10

c1ov3A_
11

c2eo3A_
12

d2oq1a1
13

c2y3aB_
14

d2oq1a2
15

d2eyva1
16

c2gsbA_
17

c2oq1A_
18

c2b3oA_
19

d1csya_
20

d1a81e2
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2lqnA_



100.0 31 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
2c2eyzA_



100.0 33 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
3c3qwxX_



100.0 100 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
4c3qwyA_



100.0 100 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
5c2eyyA_



100.0 37 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
6c2dvjA_



100.0 33 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
7c2l3sA_



100.0 29 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
8c1griA_



100.0 22 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
9c1ng2A_



100.0 17 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
10c1ov3A_



100.0 17 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
11c2eo3A_



99.9 36 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
12d2oq1a1



99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
13c2y3aB_



99.9 25 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
14d2oq1a2



99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
15d2eyva1



99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
16c2gsbA_



99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
17c2oq1A_



99.9 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
18c2b3oA_



99.9 22 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
19d1csya_



99.9 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
20d1a81e2



99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
21d1blja_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
22c2hdxB_



not modelled 99.9 25 PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
23d1a81a2



not modelled 99.9 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
24c2dlyA_



not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
25c3gqiB_



not modelled 99.9 20 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
26d1g83a2



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
27c2fo0A_



not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
28d1a81a1



not modelled 99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
29c2ge9A_



not modelled 99.9 27 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
30c3hizB_



not modelled 99.9 26 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
31d1nrva_



not modelled 99.9 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
32d1lkka_



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
33d1a81e1



not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
34c2shpA_



not modelled 99.9 27 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
35d1o48a_



not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
36d1luia_



not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
37c1mv3A_



not modelled 99.9 18 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
38c1y57A_



not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
39d3c7ia1



not modelled 99.9 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
40d1rjaa_



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
41c1x27F_



not modelled 99.9 29 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
42d1fhsa_



not modelled 99.9 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
43c3ps5A_



not modelled 99.9 26 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
44c2eobA_



not modelled 99.9 26 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
45c3nhnA_



not modelled 99.9 31 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
46d1pica_



not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
47c2ekxA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
48d2shpa2



not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
49d1udla_



not modelled 99.9 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
50c2augB_



not modelled 99.9 21 PDB header:signaling protein
Chain: B: PDB Molecule:growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
51d1bkla_



not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
52c2ci8A_



not modelled 99.9 25 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
53c2ozoA_



not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
54c1ka6A_



not modelled 99.9 26 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
55c3mazA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
56c2dlzA_



not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
57d1f2fa_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
58c1x6cA_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
59c2eo6A_



not modelled 99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
60d1qcfa2



not modelled 99.8 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
61c2c0iA_



not modelled 99.8 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
62c4fl2A_



not modelled 99.8 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
63d1jyra_



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
64d2izva2



not modelled 99.8 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
65c2h8hA_



not modelled 99.8 22 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
66c2crhA_



not modelled 99.8 21 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
67d1r1qa_



not modelled 99.8 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
68d1cwea_



not modelled 99.8 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
69c1oplA_



not modelled 99.8 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
70d1ayaa_



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
71d1d4ta_



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
72d2qmsa1



not modelled 99.8 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
73d2shpa3



not modelled 99.8 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
74d2c9wa2



not modelled 99.8 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
75c2ablA_



not modelled 99.8 28 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
76c1a81E_



not modelled 99.8 22 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
77c2ysxA_



not modelled 99.8 23 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
78c2knoA_



not modelled 99.8 30 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
79d1k9aa2



not modelled 99.8 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
80c2dcrA_



not modelled 99.8 27 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
81c2c9wA_



not modelled 99.8 23 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
82c2vifA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
83c1k9aB_



not modelled 99.8 25 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
84d1opka2



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
85c2dm0A_



not modelled 99.8 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
86c2el8A_



not modelled 99.8 28 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
87d1rpya_



not modelled 99.8 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
88d2fcia1



not modelled 99.8 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
89c1g83A_



not modelled 99.8 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
90d1i3za_



not modelled 99.8 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
91c2dbkA_



not modelled 99.8 33 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
92d1jwoa_



not modelled 99.8 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
93c2lctA_



not modelled 99.8 22 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
94d1qada_



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
95d2cs0a1



not modelled 99.8 18 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
96c2dx1A_



not modelled 99.8 14 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
97c3jv3A_



not modelled 99.8 26 PDB header:protein binding
Chain: A: PDB Molecule:intersectin-1;
PDBTitle: structure of sh3e-dh unit of murine intersectin-1l
98c1rqqC_



not modelled 99.8 25 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
99c2kk6A_



not modelled 99.8 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
100c2hmhA_



not modelled 99.8 24 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
101c3nmzD_



not modelled 99.8 11 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
102d1mila_



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
103c2rqrA_



not modelled 99.8 12 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
104d1ng2a2



not modelled 99.8 21 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
105c3gxxB_



not modelled 99.8 19 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
106c2izvA_



not modelled 99.8 23 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
107c2ed0A_



not modelled 99.8 19 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
108c2ebpA_



not modelled 99.8 22 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
109c2dybA_



not modelled 99.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: the crystal structure of human p40(phox)
110c2eyxA_



not modelled 99.8 34 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
111d1fu6a_



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
112c2cubA_



not modelled 99.8 23 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
113d1xa6a2



not modelled 99.8 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
114c2bzxA_



not modelled 99.8 38 PDB header:sh3 domain
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: atomic model of crkl-sh3c monomer
115c1x2qA_



not modelled 99.7 23 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
116c2epdA_



not modelled 99.7 16 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
117c2bz8B_



not modelled 99.7 16 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
118c2ysqA_



not modelled 99.7 14 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
119c2dl8A_



not modelled 99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
120c2nwmA_



not modelled 99.7 20 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin

Binding site prediction 

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