Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP92160
DateFri May 3 21:25:32 BST 2013
Unique Job ID892b586c2bcb4a3b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:55.703 Y:37.435 Z:41.876
Model (left) based on template d2dkqa1
Top template information
Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
Confidence and coverage
Confidence:100.0% Coverage: 35%
146 residues ( 35% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
275 residues ( 66%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSDTATTSTTVVIHLKRSNHDDASASATTAQLQQRSRYCDVSLASSEESSDLSDAEEKDD
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Disorder  ???????







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   .........70.........80.........90.........100.........110.........120
Sequence  LIRRTITSSSKDTMEEGDDDDEEEFDDVVMEEDVGGGTDANEQFSRVIQRQISGAGGGIL
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Disorder  ????????????????????????







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   .........130.........140.........150.........160.........170.........180
Sequence  KKSNGKDTSEIIHHHPLFVKDTSKYWYKPTISREQAINMLRDKPPGTFVVRDSNSFPGAF
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Disorder  ????????????????????



















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??














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   .........190.........200.........210.........220.........230.........240
Sequence  GLALKVSTPPPGVNPGDGSELVRHFLIEPSPKGVKLKGCNNEPVFGSLSALVYQHSITAL
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Disorder 






???????????





















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   .........250.........260.........270.........280.........290.........300
Sequence  ALPTKLVLPDFDPAATPEHLSATQALLEQGAACNVVYVGSVDVESLTGNECVKRSIATCS
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????????????


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?
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   .........310.........320.........330.........340.........350.........360
Sequence  QRAINGDSRAVSVHFKVSSQGVTLTDNTRKVFFRRHFNVQSVIFAGMDPIERRFENTRAL
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Disorder  ????????????





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?
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   .........370.........380.........390.........400.........410.......
Sequence  GFHDGCIAQARLFAFVARIPSSSENACHVFAELEPEQPGSAVVNFINKVMLAQKNRS
Secondary structure 




























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Disorder  ???????










































???????
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Confidence Key
High(9)                    Low (0)
?Disordered ( 49%)
Alpha helix ( 16%)
Beta strand ( 21%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2dkq chain A domain 1

3D model

Region: 260 - 415
Aligned: 146
Modelled: 156
Confidence: 100.0%
Identity: 51%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 1wvh chain A domain 1

3D model

Region: 271 - 411
Aligned: 132
Modelled: 141
Confidence: 100.0%
Identity: 51%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 2kno chain A

3D model

Region: 129 - 252
Aligned: 124
Modelled: 124
Confidence: 100.0%
Identity: 59%
PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)

Phyre2

PDB 1lkk chain A

3D model

Region: 141 - 251
Aligned: 102
Modelled: 111
Confidence: 99.9%
Identity: 27%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2oq1 chain A domain 1

3D model

Region: 141 - 266
Aligned: 112
Modelled: 124
Confidence: 99.9%
Identity: 21%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 4fl2 chain A

3D model

Region: 145 - 269
Aligned: 111
Modelled: 125
Confidence: 99.9%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2

PDB 2oq1 chain A

3D model

Region: 145 - 266
Aligned: 108
Modelled: 120
Confidence: 99.9%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2

PDB 1qcf chain A domain 2

3D model

Region: 144 - 249
Aligned: 97
Modelled: 106
Confidence: 99.9%
Identity: 31%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1f2f chain A

3D model

Region: 143 - 249
Aligned: 98
Modelled: 107
Confidence: 99.9%
Identity: 29%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1g83 chain A domain 2

3D model

Region: 141 - 249
Aligned: 100
Modelled: 107
Confidence: 99.9%
Identity: 28%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1a81 chain A domain 1

3D model

Region: 143 - 266
Aligned: 110
Modelled: 122
Confidence: 99.9%
Identity: 22%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1lui chain A

3D model

Region: 141 - 251
Aligned: 104
Modelled: 111
Confidence: 99.9%
Identity: 27%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2y3a chain B

3D model

Region: 140 - 254
Aligned: 100
Modelled: 115
Confidence: 99.9%
Identity: 31%
PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941

Phyre2

PDB 2dly chain A

3D model

Region: 141 - 260
Aligned: 106
Modelled: 120
Confidence: 99.9%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase

Phyre2

PDB 1blj chain A

3D model

Region: 136 - 254
Aligned: 109
Modelled: 119
Confidence: 99.9%
Identity: 32%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2ozo chain A

3D model

Region: 145 - 269
Aligned: 111
Modelled: 125
Confidence: 99.9%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2

PDB 1a81 chain E domain 1

3D model

Region: 141 - 260
Aligned: 106
Modelled: 120
Confidence: 99.9%
Identity: 22%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1bkl chain A

3D model

Region: 144 - 253
Aligned: 101
Modelled: 110
Confidence: 99.9%
Identity: 29%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1opk chain A domain 2

3D model

Region: 141 - 253
Aligned: 99
Modelled: 113
Confidence: 99.8%
Identity: 31%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2oq1 chain A domain 2

3D model

Region: 143 - 252
Aligned: 95
Modelled: 108
Confidence: 99.8%
Identity: 25%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
1

d2dkqa1
2

d1wvha1
3

c2knoA_
4

d1lkka_
5

d2oq1a1
6

c4fl2A_
7

c2oq1A_
8

d1qcfa2
9

d1f2fa_
10

d1g83a2
11

d1a81a1
12

d1luia_
13

c2y3aB_
14

c2dlyA_
15

d1blja_
16

c2ozoA_
17

d1a81e1
18

d1bkla_
19

d1opka2
20

d2oq1a2
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2dkqa1



100.0 51 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
2d1wvha1



100.0 51 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
3c2knoA_



100.0 59 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
4d1lkka_



99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
5d2oq1a1



99.9 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
6c4fl2A_



99.9 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
7c2oq1A_



99.9 22 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
8d1qcfa2



99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
9d1f2fa_



99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
10d1g83a2



99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
11d1a81a1



99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
12d1luia_



99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
13c2y3aB_



99.9 31 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
14c2dlyA_



99.9 25 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
15d1blja_



99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
16c2ozoA_



99.9 22 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
17d1a81e1



99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
18d1bkla_



99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
19d1opka2



99.8 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
20d2oq1a2



99.8 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
21c1x27F_



not modelled 99.8 26 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
22c2ablA_



not modelled 99.8 33 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
23d1a81a2



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
24d1cwea_



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
25c2fo0A_



not modelled 99.8 27 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
26c3nhnA_



not modelled 99.8 30 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
27d1jwoa_



not modelled 99.8 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
28d1o48a_



not modelled 99.8 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
29c2ge9A_



not modelled 99.8 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
30c1g83A_



not modelled 99.8 27 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
31d1k9aa2



not modelled 99.8 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
32d1rjaa_



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
33c1y57A_



not modelled 99.8 24 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
34c2ekxA_



not modelled 99.8 27 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
35c2augB_



not modelled 99.8 28 PDB header:signaling protein
Chain: B: PDB Molecule:growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
36c3hizB_



not modelled 99.8 30 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
37d1nrva_



not modelled 99.8 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
38d2qmsa1



not modelled 99.8 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
39c2gsbA_



not modelled 99.8 21 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
40d1a81e2



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
41c2lctA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
42c2dlzA_



not modelled 99.8 22 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
43d1csya_



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
44c1a81E_



not modelled 99.8 21 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
45c1k9aB_



not modelled 99.8 29 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
46c2crhA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
47c2ysxA_



not modelled 99.8 25 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
48d2eyva1



not modelled 99.8 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
49c2eo6A_



not modelled 99.8 23 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
50d1fhsa_



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
51c1ka6A_



not modelled 99.8 20 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
52d1i3za_



not modelled 99.8 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
53c2c0iA_



not modelled 99.8 25 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
54c2vifA_



not modelled 99.8 23 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
55c2eo3A_



not modelled 99.8 28 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
56d2izva2



not modelled 99.8 19 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
57c1oplA_



not modelled 99.8 29 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
58c2h8hA_



not modelled 99.8 24 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
59d1d4ta_



not modelled 99.8 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
60c1x6cA_



not modelled 99.8 31 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
61d2shpa2



not modelled 99.8 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
62c2el8A_



not modelled 99.8 18 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
63d2shpa3



not modelled 99.8 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
64c2eobA_



not modelled 99.8 26 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
65c2dm0A_



not modelled 99.8 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
66c2shpA_



not modelled 99.8 24 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
67c2lqnA_



not modelled 99.8 28 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
68c2c9wA_



not modelled 99.8 24 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
69d1pica_



not modelled 99.8 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
70c2b3oA_



not modelled 99.8 30 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
71d1ayaa_



not modelled 99.8 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
72d1r1qa_



not modelled 99.8 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
73d2cs0a1



not modelled 99.8 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
74d3c7ia1



not modelled 99.8 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
75c2hmhA_



not modelled 99.8 21 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
76c2izvA_



not modelled 99.8 18 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
77c2hdxB_



not modelled 99.7 18 PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
78d1qada_



not modelled 99.7 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
79c3gqiB_



not modelled 99.7 29 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
80c3ps5A_



not modelled 99.7 26 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
81d2c9wa2



not modelled 99.7 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
82d2fcia1



not modelled 99.7 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
83d1jyra_



not modelled 99.7 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
84d1fu6a_



not modelled 99.7 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
85c3gxxB_



not modelled 99.7 20 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
86c3mazA_



not modelled 99.7 11 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
87c2kk6A_



not modelled 99.7 27 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
88c2ci8A_



not modelled 99.7 26 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
89d1mila_



not modelled 99.7 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
90c3d8dA_



not modelled 99.7 25 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family b member
PDBTitle: crystal structure of the human fe65-ptb1 domain
91c2m38A_



not modelled 99.7 20 PDB header:peptide binding protein
Chain: A: PDB Molecule:ankyrin repeat and sterile alpha motif domain-containing
PDBTitle: ptb domain of aida1
92c3so6A_



not modelled 99.7 21 PDB header:protein binding/protein transport
Chain: A: PDB Molecule:ldl receptor adaptor protein;
PDBTitle: crystal structure of the ldl receptor tail in complex with autosomal2 recessive hypercholesterolemia ptb domain
93d1rpya_



not modelled 99.6 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
94c2dcrA_



not modelled 99.6 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
95c1rqqC_



not modelled 99.6 23 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
96d1wgua_



not modelled 99.6 19 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
97d1ddma_



not modelled 99.6 23 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
98c2eyzA_



not modelled 99.6 27 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
99c2dvjA_



not modelled 99.6 29 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
100c2elaB_



not modelled 99.6 23 PDB header:cell cycle
Chain: B: PDB Molecule:adapter protein containing ph domain, ptb domain
PDBTitle: crystal structure of the ptb domain of human appl1
101c3qwxX_



not modelled 99.6 27 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
102c3qwyA_



not modelled 99.6 27 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
103c2yt1A_



not modelled 99.6 23 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 protein and amyloid beta a4
PDBTitle: solution structure of the chimera of the c-terminal tail2 peptide of app and the c-terminal pid domain of fe65l
104c3dxeC_



not modelled 99.6 18 PDB header:protein binding
Chain: C: PDB Molecule:amyloid beta a4 protein-binding family b member
PDBTitle: crystal structure of the intracellular domain of human app2 (t668a mutant) in complex with fe65-ptb2
105d1xa6a2



not modelled 99.6 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
106c2eyyA_



not modelled 99.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
107d1wj1a_



not modelled 99.6 20 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
108d1ntva_



not modelled 99.6 15 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
109d1p3ra_



not modelled 99.6 18 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
110d1uura3



not modelled 99.5 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
111c2dx0B_



not modelled 99.5 26 PDB header:hydrolase
Chain: B: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
112c3or8A_



not modelled 99.5 24 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
113c2cr4A_



not modelled 99.5 19 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
114c2yszA_



not modelled 99.5 24 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family
PDBTitle: solution structure of the chimera of the c-terminal pid2 domain of fe65l and the c-terminal tail peptide of app
115c2dyqA_



not modelled 99.3 19 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family b member
PDBTitle: crystal structure of the c-terminal phophotyrosine interaction domain2 of human apbb3
116c2xp1A_



not modelled 99.3 22 PDB header:transcription
Chain: A: PDB Molecule:spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
117d2cy5a1



not modelled 99.2 17 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
118c3sv1C_



not modelled 99.2 19 PDB header:protein binding
Chain: C: PDB Molecule:amyloid beta a4 precursor protein-binding family a member
PDBTitle: crystal structure of app peptide bound rat mint2 parm
119d1bf5a3



not modelled 99.2 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
120c1xa6A_



not modelled 99.2 23 PDB header:signaling protein
Chain: A: PDB Molecule:beta2-chimaerin;
PDBTitle: crystal structure of the human beta2-chimaerin

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