Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionO62482
DateFri May 3 21:35:38 BST 2013
Unique Job ID907f535300166207

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:64.269 Y:57.012 Z:51.091
Model (left) based on template c1griA_
Top template information
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
Confidence and coverage
Confidence:100.0% Coverage: 40%
188 residues ( 40% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Warning: 58% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MCDLPKKDVEFKEIDAIYENMKIKNSQRQRSQNSLDLIRITNNLDETTKSLNLYLQQIDA
Secondary structure 
SS confidence 
Disorder  ?????????????????
?????????
??
????
????????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  TWKRSKSQPIMKGPNDQYNNQERVKQSNEEELLRLKAEKLAEELRKEKERKHSFIPSSAP
Secondary structure 
SS confidence 
Disorder  ?????????????????????????????
?????
????????????????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  SLQNNMDRLNSLLYDFSSDIQEPAHRDYTPQPVMTATAVYKFEPRSARELPLNRGDIIRI
Secondary structure 
SS confidence 
Disorder  ?????????????????????????????????
????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  IREVDGYWMEGERNGRSGIFPTSYVQINTGNQGDSQKMRAIYPFTARSDTELSLKRGEII
Secondary structure 
SS confidence 
Disorder 
?
?
??
??????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  TRRRQIDSNWLEGSNQIGIVGIFPASYVEPIEQVEQHIPTIVPNRPKTPKIEDQVYNQVY
Secondary structure 
SS confidence 
Disorder 
?
?
????????????????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  KPNETVIMQSNQGYYDKAAVVPNNKVRFDLPSGSDSNLQMSLNPHQNQFPPTHTQTSTQQ
Secondary structure 
SS confidence 
Disorder  ???????
????????????????????????????????????????????????????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  PSNYGMKKIEYEREKVVEEVPPMHMDQYRKLNDEPKNPKKDTNILMNAASLIPKGSEMYR
Secondary structure 
SS confidence 
Disorder  ???????????????????????????????????????????????????
??
Disorder confidence 
 
   .........430.........440.........450.........460.........470...
Sequence  AVYPYQPQKEDELQLYTNDIIFVVEKCDDGWFIGTSLRTGDFGIFPGNYVKRH
Secondary structure 
SS confidence 
Disorder 
??
?
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 58%)
Alpha helix ( 18%)
Beta strand ( 16%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1gri chain A

3D model

Region: 154 - 471
Aligned: 188
Modelled: 193
Confidence: 100.0%
Identity: 30%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 2lqn chain A

3D model

Region: 208 - 471
Aligned: 173
Modelled: 175
Confidence: 100.0%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2l3s chain A

3D model

Region: 215 - 471
Aligned: 159
Modelled: 161
Confidence: 99.9%
Identity: 19%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 2eyz chain A

3D model

Region: 208 - 471
Aligned: 166
Modelled: 166
Confidence: 99.9%
Identity: 17%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 1ov3 chain A

3D model

Region: 155 - 472
Aligned: 123
Modelled: 125
Confidence: 99.9%
Identity: 31%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 1ng2 chain A

3D model

Region: 155 - 308
Aligned: 153
Modelled: 154
Confidence: 99.9%
Identity: 18%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2

PDB 1mv3 chain A

3D model

Region: 276 - 472
Aligned: 197
Modelled: 197
Confidence: 99.9%
Identity: 14%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 2rqr chain A

3D model

Region: 358 - 471
Aligned: 114
Modelled: 114
Confidence: 99.7%
Identity: 15%
PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex

Phyre2

PDB 1ng2 chain A domain 2

3D model

Region: 406 - 471
Aligned: 64
Modelled: 64
Confidence: 99.7%
Identity: 25%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 2dx1 chain A

3D model

Region: 418 - 471
Aligned: 52
Modelled: 54
Confidence: 99.7%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 3nmz chain D

3D model

Region: 397 - 471
Aligned: 73
Modelled: 75
Confidence: 99.7%
Identity: 19%
PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef

Phyre2

PDB 2kym chain A

3D model

Region: 414 - 471
Aligned: 58
Modelled: 58
Confidence: 99.7%
Identity: 24%
PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide

Phyre2

PDB 2yt6 chain A

3D model

Region: 390 - 472
Aligned: 83
Modelled: 83
Confidence: 99.7%
Identity: 17%
PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1

Phyre2

PDB 2jxb chain A

3D model

Region: 386 - 472
Aligned: 85
Modelled: 87
Confidence: 99.7%
Identity: 18%
PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex

Phyre2

PDB 1x6g chain A

3D model

Region: 401 - 471
Aligned: 71
Modelled: 71
Confidence: 99.7%
Identity: 11%
PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.

Phyre2

PDB 2e5k chain A

3D model

Region: 401 - 472
Aligned: 72
Modelled: 72
Confidence: 99.7%
Identity: 36%
PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1

Phyre2

PDB 2eyy chain A

3D model

Region: 386 - 472
Aligned: 86
Modelled: 87
Confidence: 99.7%
Identity: 19%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i

Phyre2

PDB 2fpe chain B

3D model

Region: 414 - 472
Aligned: 59
Modelled: 59
Confidence: 99.7%
Identity: 32%
PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain

Phyre2

PDB 2oi3 chain A

3D model

Region: 392 - 472
Aligned: 80
Modelled: 81
Confidence: 99.7%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)

Phyre2

PDB 2ct3 chain A

3D model

Region: 412 - 471
Aligned: 60
Modelled: 60
Confidence: 99.7%
Identity: 53%
PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein

Phyre2
1
c1griA_
2
c2lqnA_
3
c2l3sA_
4
c2eyzA_
5
c1ov3A_
6
c1ng2A_
7
c1mv3A_
8
c2rqrA_
9
d1ng2a2
10
c2dx1A_
11
c3nmzD_
12
c2kymA_
13
c2yt6A_
14
c2jxbA_
15
c1x6gA_
16
c2e5kA_
17
c2eyyA_
18
c2fpeB_
19
c2oi3A_
20
c2ct3A_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1griA_
100.0 30 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
2c2lqnA_
100.0 23 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
3c2l3sA_
99.9 19 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
4c2eyzA_
99.9 17 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
5c1ov3A_
99.9 31 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
6c1ng2A_
99.9 18 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
7c1mv3A_
99.9 14 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
8c2rqrA_
99.7 15 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
9d1ng2a2
99.7 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
10c2dx1A_
99.7 23 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
11c3nmzD_
99.7 19 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
12c2kymA_
99.7 24 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
13c2yt6A_
99.7 17 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
14c2jxbA_
99.7 18 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
15c1x6gA_
99.7 11 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
16c2e5kA_
99.7 36 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
17c2eyyA_
99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
18c2fpeB_
99.7 32 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
19c2oi3A_
99.7 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
20c2ct3A_
99.7 53 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
21d1ov3a2
not modelled 99.7 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
22c2cudA_
not modelled 99.7 18 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
23c1zukA_
not modelled 99.7 31 PDB header:contractile protein
Chain: A: PDB Molecule:myosin tail region-interacting protein mti1;
PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17
24c3rnjA_
not modelled 99.7 25 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)
25c2lj0A_
not modelled 99.7 57 PDB header:signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: the third sh3 domain of r85fl
26c2yupA_
not modelled 99.7 24 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
27d1phta_
not modelled 99.6 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
28d1ue9a_
not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
29c1x2qA_
not modelled 99.6 26 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
30c3qwyA_
not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
31c2j06B_
not modelled 99.6 30 PDB header:signal transduction
Chain: B: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution
32d1bb9a_
not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
33c1bb9A_
not modelled 99.6 32 PDB header:transferase
Chain: A: PDB Molecule:amphiphysin 2;
PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2
34c2ysqA_
not modelled 99.6 21 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
35c3qwxX_
not modelled 99.6 18 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
36c2rqvA_
not modelled 99.6 30 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of sh3ci domain of bem1p
37c1x6bA_
not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
38c1zlmA_
not modelled 99.6 36 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
39c2cubA_
not modelled 99.6 30 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
40c2l0aA_
not modelled 99.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
41c2xmfA_
not modelled 99.6 42 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
42d1jo8a_
not modelled 99.6 37 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
43d1k4us_
not modelled 99.6 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
44c2kt1A_
not modelled 99.6 33 PDB header:protein binding
Chain: A: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: solution nmr structure of the sh3 domain from the p85beta2 subunit of phosphatidylinositol 3-kinase from h.sapiens,3 northeast structural genomics consortium target hr5531e
45c2yunA_
not modelled 99.6 36 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
46c4afzC_
not modelled 99.6 27 PDB header:hydrolase/de novo protein
Chain: C: PDB Molecule:fynomer;
PDBTitle: human chymase - fynomer complex
47c2cucA_
not modelled 99.6 37 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2
48c2lcsA_
not modelled 99.6 25 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:nap1-binding protein 2;
PDBTitle: yeast nbp2p sh3 domain in complex with a peptide from ste20p
49c1yn8E_
not modelled 99.6 27 PDB header:unknown function
Chain: E: PDB Molecule:nap1-binding protein 2;
PDBTitle: sh3 domain of yeast nbp2
50d1wiea_
not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
51c2ed0A_
not modelled 99.6 38 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
52d1gl5a_
not modelled 99.6 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
53c2df6A_
not modelled 99.6 37 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
54c2dlpA_
not modelled 99.6 21 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
55c2ekhA_
not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
56d1gcqa_
not modelled 99.6 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
57c2d8jA_
not modelled 99.6 23 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh3 domain of fyn-related kinase
58c1zuyB_
not modelled 99.6 30 PDB header:contractile protein
Chain: B: PDB Molecule:myosin-5 isoform;
PDBTitle: high-resolution structure of yeast myo5 sh3 domain
59d1uffa_
not modelled 99.6 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
60c2ed1A_
not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
61c2egcA_
not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the fifth sh3 domain from human2 kiaa0418 protein
62c2yuoA_
not modelled 99.6 27 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
63d1oeba_
not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
64c2djqA_
not modelled 99.6 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
65d1sema_
not modelled 99.6 34 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
66c2nwmA_
not modelled 99.6 36 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
67c2epdA_
not modelled 99.6 21 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
68d1spka_
not modelled 99.6 22 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
69c2i0nA_
not modelled 99.6 24 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
70c4glmD_
not modelled 99.6 36 PDB header:signaling protein
Chain: D: PDB Molecule:dynamin-binding protein;
PDBTitle: crystal structure of the sh3 domain of dnmbp protein [homo sapiens]
71c2dmoA_
not modelled 99.6 29 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
72c2dl4A_
not modelled 99.6 29 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
73c1x43A_
not modelled 99.6 17 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
74c3cqtA_
not modelled 99.6 26 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: n53i v55l mutant of fyn sh3 domain
75d1uj0a_
not modelled 99.6 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
76c2ebpA_
not modelled 99.6 27 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
77d1uuea_
not modelled 99.6 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
78c4esrB_
not modelled 99.6 36 PDB header:protein binding
Chain: B: PDB Molecule:jouberin;
PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors
79c2rf0D_
not modelled 99.6 36 PDB header:transferase
Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10;
PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
80d1pwta_
not modelled 99.6 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
81d1efna_
not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
82c1zx6A_
not modelled 99.6 40 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
83c2eyxA_
not modelled 99.6 21 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
84c2enmA_
not modelled 99.6 22 PDB header:endocytosis
Chain: A: PDB Molecule:sorting nexin-9;
PDBTitle: solution structure of the sh3 domain from mouse sorting2 nexin-9
85c1z9zA_
not modelled 99.6 21 PDB header:structural protein
Chain: A: PDB Molecule:cytoskeleton assembly control protein sla1;
PDBTitle: crystal structure of yeast sla1 sh3 domain 3
86c2dnuA_
not modelled 99.6 31 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
87c2egeA_
not modelled 99.6 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein kiaa1666;
PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
88c2bz8B_
not modelled 99.6 37 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
89d1utia_
not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
90c2d1xD_
not modelled 99.6 41 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
91d1gria2
not modelled 99.6 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
92c2csqA_
not modelled 99.6 21 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
93c1x2pA_
not modelled 99.6 25 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 2;
PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
94d1wlpb2
not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
95c2d8hA_
not modelled 99.6 24 PDB header:unknown function
Chain: A: PDB Molecule:sh3yl1 protein;
PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1
96d1fmka1
not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
97c2drmB_
not modelled 99.6 38 PDB header:contractile protein
Chain: B: PDB Molecule:acanthamoeba myosin ib;
PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
98d1arka_
not modelled 99.6 39 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
99d1u06a1
not modelled 99.6 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
100d1ujya_
not modelled 99.6 34 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
101d1shfa_
not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
102c2dilA_
not modelled 99.6 39 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
103c2dl8A_
not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
104d2v1ra1
not modelled 99.6 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
105d2iima1
not modelled 99.6 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
106c2eqiA_
not modelled 99.6 31 PDB header:immune system, hydrolase
Chain: A: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2
107c2pqhA_
not modelled 99.6 26 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal
108c2ke9A_
not modelled 99.6 30 PDB header:protein binding
Chain: A: PDB Molecule:caskin-2;
PDBTitle: nmr solution structure of the caskin sh3 domain
109d1e6ga_
not modelled 99.6 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
110c2dl3A_
not modelled 99.6 29 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
111c2jteA_
not modelled 99.6 27 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: third sh3 domain of cd2ap
112c2dbmA_
not modelled 99.6 36 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:sh3-containing grb2-like protein 2;
PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2
113c2ct4A_
not modelled 99.6 13 PDB header:signaling protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: solution strutcure of the sh3 domain of the cdc42-2 interacting protein 4
114d1udla_
not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
115d1ckaa_
not modelled 99.6 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
116c2kgtA_
not modelled 99.6 17 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase 6;
PDBTitle: solution structure of sh3 domain of ptk6
117d1y57a1
not modelled 99.6 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
118c4igzA_
not modelled 99.6 35 PDB header:protein binding
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 2;
PDBTitle: crystal structure of the sh3 domain of human sorbin and sh3 domain-2 containing protein 2
119c2dl5A_
not modelled 99.6 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:kiaa0769 protein;
PDBTitle: solution structure of the first sh3 domain of human2 kiaa0769 protein
120c1negA_
not modelled 99.6 26 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite