Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionE6N0W1
DateFri May 3 21:47:45 BST 2013
Unique Job IDd228f0f148128221

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:57.723 Y:57.197 Z:48.946
Model (left) based on template c1griA_
Top template information
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
Confidence and coverage
Confidence: 99.9% Coverage: 30%
192 residues ( 30% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
265 residues ( 42%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRSTRDEKVARIKELQETNQKTAIESQELGHQLLQKQSAHKETTQRKSELEALRRKRDAI
Secondary structure 
SS confidence 
Disorder  ????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  RKAIEDAALELSTEKEKSYNQTEILKTNKEKYKTDVYSKLVAKREEYRNSFELLVHAQTH
Secondary structure 
SS confidence 
Disorder 
????????
??????????????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ARSKIGEFEAKSAPASAAPAPAPAPAPTTTNGFPANFNDAFGEFDKTDASQRFDADFGAT
Secondary structure 
SS confidence 
Disorder  ????????????????????????????????????????????????????????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  STADPFAQIAQAPAHSKGAVDQSAFNIHDTYKCRALFAFEARSEDELSFEPGDVIIVFQS
Secondary structure 
SS confidence 
Disorder  ??????????????????????????????
?????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  HAAEPGWRAGQLREKVGWFPEAFVEAIAAVPTPGGDPPIQNMPPNMTPSSSVDQIGVKAA
Secondary structure 
SS confidence 
Disorder 
?
?????????????????????????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  RKAEIAAAMGLTEGGAPPASSAPAAAAVISQCIAQFQWRARNEEDLSFAKGDTIEVLEKQ
Secondary structure 
SS confidence 
Disorder  ?????????????????????????????
????
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  EMKWKGRNPAGEIGWFPKSYVKEVGATTSTTTPIVSPSKASAGAPGAAAGAQYDVVPSDV
Secondary structure 
SS confidence 
Disorder 
?
???????????????????????????????????
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  TLQASETAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKNDEWWKGRCNGREGIFPAN
Secondary structure 
SS confidence 
Disorder  ???????????
?
??????
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  YVEISVQQAGDPTPPTQAPTPAAPPTVLCEAKVVVDFVASAPNQLGIKVGEIVKIREKSA
Secondary structure 
SS confidence 
Disorder 
???
?
???????????????
?
???
????????????????
?????
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  AGWWEGELIRNGKPIAGWFPGEYVKVLEEAASPATRATAVYDYEASQPDELGFKTGDVII
Secondary structure 
SS confidence 
Disorder  ????????????????????
?
??
Disorder confidence 
 
   .........610.........620.........630..
Sequence  VTDKSEAEWWSGHREQDPSKSGLFPSNYVQQQ
Secondary structure 
SS confidence 
Disorder 
?
??????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 49%)
Alpha helix ( 20%)
Beta strand ( 19%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1gri chain A

3D model

Region: 331 - 630
Aligned: 192
Modelled: 200
Confidence: 99.9%
Identity: 26%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 2lqn chain A

3D model

Region: 307 - 631
Aligned: 190
Modelled: 193
Confidence: 99.9%
Identity: 24%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2eyz chain A

3D model

Region: 312 - 631
Aligned: 176
Modelled: 179
Confidence: 99.9%
Identity: 28%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 2l3s chain A

3D model

Region: 329 - 630
Aligned: 158
Modelled: 161
Confidence: 99.9%
Identity: 23%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 1ov3 chain A

3D model

Region: 501 - 631
Aligned: 124
Modelled: 131
Confidence: 99.8%
Identity: 26%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 1ng2 chain A

3D model

Region: 509 - 630
Aligned: 115
Modelled: 118
Confidence: 99.8%
Identity: 27%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2

PDB 1mv3 chain A

3D model

Region: 487 - 631
Aligned: 145
Modelled: 145
Confidence: 99.8%
Identity: 20%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 2dx1 chain A

3D model

Region: 576 - 630
Aligned: 52
Modelled: 55
Confidence: 99.7%
Identity: 42%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 2rqr chain A

3D model

Region: 518 - 630
Aligned: 112
Modelled: 113
Confidence: 99.7%
Identity: 15%
PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex

Phyre2

PDB 1ng2 chain A domain 2

3D model

Region: 568 - 630
Aligned: 60
Modelled: 63
Confidence: 99.7%
Identity: 30%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 2kym chain A

3D model

Region: 573 - 630
Aligned: 58
Modelled: 58
Confidence: 99.7%
Identity: 24%
PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide

Phyre2

PDB 1udl chain A

3D model

Region: 550 - 630
Aligned: 78
Modelled: 81
Confidence: 99.6%
Identity: 44%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 3nmz chain D

3D model

Region: 550 - 630
Aligned: 78
Modelled: 81
Confidence: 99.6%
Identity: 29%
PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef

Phyre2

PDB 1zuk chain A

3D model

Region: 571 - 630
Aligned: 60
Modelled: 60
Confidence: 99.6%
Identity: 28%
PDB header:contractile protein
Chain: A: PDB Molecule:myosin tail region-interacting protein mti1;
PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17

Phyre2

PDB 1zlm chain A

3D model

Region: 572 - 632
Aligned: 58
Modelled: 58
Confidence: 99.6%
Identity: 43%
PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor

Phyre2

PDB 2ed1 chain A

3D model

Region: 566 - 630
Aligned: 65
Modelled: 65
Confidence: 99.6%
Identity: 38%
PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein

Phyre2

PDB 2eyy chain A

3D model

Region: 558 - 631
Aligned: 72
Modelled: 74
Confidence: 99.6%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i

Phyre2

PDB 2rqv chain A

3D model

Region: 570 - 630
Aligned: 61
Modelled: 61
Confidence: 99.6%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of sh3ci domain of bem1p

Phyre2

PDB 2yt6 chain A

3D model

Region: 550 - 630
Aligned: 80
Modelled: 81
Confidence: 99.6%
Identity: 29%
PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1

Phyre2

PDB 1ue9 chain A

3D model

Region: 570 - 630
Aligned: 61
Modelled: 61
Confidence: 99.6%
Identity: 26%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2
1
c1griA_
2
c2lqnA_
3
c2eyzA_
4
c2l3sA_
5
c1ov3A_
6
c1ng2A_
7
c1mv3A_
8
c2dx1A_
9
c2rqrA_
10
d1ng2a2
11
c2kymA_
12
d1udla_
13
c3nmzD_
14
c1zukA_
15
c1zlmA_
16
c2ed1A_
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c2eyyA_
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c2rqvA_
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c2yt6A_
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d1ue9a_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1griA_
99.9 26 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
2c2lqnA_
99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
3c2eyzA_
99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
4c2l3sA_
99.9 23 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
5c1ov3A_
99.8 26 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
6c1ng2A_
99.8 27 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
7c1mv3A_
99.8 20 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
8c2dx1A_
99.7 42 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
9c2rqrA_
99.7 15 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
10d1ng2a2
99.7 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
11c2kymA_
99.7 24 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
12d1udla_
99.6 44 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
13c3nmzD_
99.6 29 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
14c1zukA_
99.6 28 PDB header:contractile protein
Chain: A: PDB Molecule:myosin tail region-interacting protein mti1;
PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17
15c1zlmA_
99.6 43 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
16c2ed1A_
99.6 38 PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
17c2eyyA_
99.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
18c2rqvA_
99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of sh3ci domain of bem1p
19c2yt6A_
99.6 29 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
20d1ue9a_
99.6 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
21c3qwyA_
not modelled 99.6 22 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
22d1ov3a2
not modelled 99.6 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
23c2jxbA_
not modelled 99.6 28 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
24c1x2qA_
not modelled 99.6 40 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
25c2yupA_
not modelled 99.6 27 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
26d1uj0a_
not modelled 99.6 48 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
27c2df6A_
not modelled 99.6 39 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
28c1bb9A_
not modelled 99.6 32 PDB header:transferase
Chain: A: PDB Molecule:amphiphysin 2;
PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2
29d1bb9a_
not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
30c3qwxX_
not modelled 99.6 21 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
31d1i1ja_
not modelled 99.6 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
32c2nwmA_
not modelled 99.6 30 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
33c2d8jA_
not modelled 99.6 32 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh3 domain of fyn-related kinase
34c2lj0A_
not modelled 99.6 29 PDB header:signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: the third sh3 domain of r85fl
35c2ysqA_
not modelled 99.6 37 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
36d1k4us_
not modelled 99.6 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
37c2fpeB_
not modelled 99.6 20 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
38c3rnjA_
not modelled 99.6 28 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)
39d1oeba_
not modelled 99.6 47 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
40c2l0aA_
not modelled 99.6 42 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
41c2e5kA_
not modelled 99.6 23 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
42c4glmD_
not modelled 99.6 33 PDB header:signaling protein
Chain: D: PDB Molecule:dynamin-binding protein;
PDBTitle: crystal structure of the sh3 domain of dnmbp protein [homo sapiens]
43c2ed0A_
not modelled 99.6 34 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
44c2yunA_
not modelled 99.6 38 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
45d1gcqa_
not modelled 99.6 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
46c2ebpA_
not modelled 99.6 28 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
47c2yuoA_
not modelled 99.6 32 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
48c2cubA_
not modelled 99.6 32 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
49c4esrB_
not modelled 99.6 39 PDB header:protein binding
Chain: B: PDB Molecule:jouberin;
PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors
50c2dlpA_
not modelled 99.6 30 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
51c1x6gA_
not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
52c2ekhA_
not modelled 99.6 28 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
53c2j06B_
not modelled 99.6 27 PDB header:signal transduction
Chain: B: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution
54c2xmfA_
not modelled 99.6 36 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
55c2ke9A_
not modelled 99.6 31 PDB header:protein binding
Chain: A: PDB Molecule:caskin-2;
PDBTitle: nmr solution structure of the caskin sh3 domain
56c2epdA_
not modelled 99.6 28 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
57c1wx6A_
not modelled 99.6 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:cytoplasmic protein nck2;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2
58d1utia_
not modelled 99.6 50 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
59c2ct3A_
not modelled 99.5 33 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
60c2djqA_
not modelled 99.5 33 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
61c1x6bA_
not modelled 99.5 21 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
62d1gria2
not modelled 99.5 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
63d1uuea_
not modelled 99.5 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
64c2eyxA_
not modelled 99.5 23 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
65d1sema_
not modelled 99.5 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
66d1wlpb2
not modelled 99.5 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
67c2egcA_
not modelled 99.5 24 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the fifth sh3 domain from human2 kiaa0418 protein
68c2cudA_
not modelled 99.5 16 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
69c2m0yA_
not modelled 99.5 27 PDB header:apoptosis
Chain: A: PDB Molecule:dedicator of cytokinesis protein 1;
PDBTitle: solution structure of the sh3 domain of dock180
70d1ckaa_
not modelled 99.5 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
71c2enmA_
not modelled 99.5 29 PDB header:endocytosis
Chain: A: PDB Molecule:sorting nexin-9;
PDBTitle: solution structure of the sh3 domain from mouse sorting2 nexin-9
72c2egeA_
not modelled 99.5 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein kiaa1666;
PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
73c2dl4A_
not modelled 99.5 30 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
74c1zx6A_
not modelled 99.5 34 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
75c2dmoA_
not modelled 99.5 21 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
76c2kgtA_
not modelled 99.5 27 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase 6;
PDBTitle: solution structure of sh3 domain of ptk6
77d1cska_
not modelled 99.5 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
78c2d1xD_
not modelled 99.5 38 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
79d1uffa_
not modelled 99.5 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
80c2kbtA_
not modelled 99.5 37 PDB header:signaling protein
Chain: A: PDB Molecule:chimera of proto-oncogene vav, linker,
PDBTitle: attachment of an nmr-invisible solubility enhancement tag2 (inset) using a sortase-mediated protein ligation method
81d1phta_
not modelled 99.5 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
82c2i0nA_
not modelled 99.5 32 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
83c2dl8A_
not modelled 99.5 26 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
84c2csqA_
not modelled 99.5 28 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
85d1pwta_
not modelled 99.5 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
86d2v1ra1
not modelled 99.5 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
87d1gl5a_
not modelled 99.5 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
88c2lcsA_
not modelled 99.5 33 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:nap1-binding protein 2;
PDBTitle: yeast nbp2p sh3 domain in complex with a peptide from ste20p
89c2dbkA_
not modelled 99.5 21 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
90c1zuyB_
not modelled 99.5 36 PDB header:contractile protein
Chain: B: PDB Molecule:myosin-5 isoform;
PDBTitle: high-resolution structure of yeast myo5 sh3 domain
91c2rf0D_
not modelled 99.5 40 PDB header:transferase
Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10;
PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
92c2dnuA_
not modelled 99.5 26 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
93d1u06a1
not modelled 99.5 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
94c2dilA_
not modelled 99.5 34 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
95d1u5sa1
not modelled 99.5 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
96c2bz8B_
not modelled 99.5 37 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
97d1wiea_
not modelled 99.5 22 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
98c2oi3A_
not modelled 99.5 32 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
99c1w70A_
not modelled 99.5 35 PDB header:sh3 domain
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
100c1x2pA_
not modelled 99.5 31 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 2;
PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
101c2d8hA_
not modelled 99.5 28 PDB header:unknown function
Chain: A: PDB Molecule:sh3yl1 protein;
PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1
102c2dl7A_
not modelled 99.5 33 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:kiaa0769 protein;
PDBTitle: solution structure of the second sh3 domain of human2 kiaa0769 protein
103d1jo8a_
not modelled 99.5 48 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
104c2drmB_
not modelled 99.5 50 PDB header:contractile protein
Chain: B: PDB Molecule:acanthamoeba myosin ib;
PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
105c2dl3A_
not modelled 99.5 25 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
106c4igzA_
not modelled 99.5 38 PDB header:protein binding
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 2;
PDBTitle: crystal structure of the sh3 domain of human sorbin and sh3 domain-2 containing protein 2
107c2dbmA_
not modelled 99.5 39 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:sh3-containing grb2-like protein 2;
PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2
108c2js0A_
not modelled 99.5 37 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of second sh3 domain of adaptor nck
109c1x43A_
not modelled 99.5 25 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
110c2pqhA_
not modelled 99.5 28 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal
111c2eqiA_
not modelled 99.5 37 PDB header:immune system, hydrolase
Chain: A: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2
112d1t0ha_
not modelled 99.5 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
113d1qlya_
not modelled 99.5 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
114c2krnA_
not modelled 99.5 42 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: high resolution structure of the second sh3 domain of cd2ap
115c4afzC_
not modelled 99.5 30 PDB header:hydrolase/de novo protein
Chain: C: PDB Molecule:fynomer;
PDBTitle: human chymase - fynomer complex
116c2cucA_
not modelled 99.5 31 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2
117d1e6ga_
not modelled 99.5 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
118c1yn8E_
not modelled 99.5 34 PDB header:unknown function
Chain: E: PDB Molecule:nap1-binding protein 2;
PDBTitle: sh3 domain of yeast nbp2
119c2egaA_
not modelled 99.5 25 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein
120c1x69A_
not modelled 99.5 33 PDB header:signaling protein
Chain: A: PDB Molecule:cortactin isoform a;
PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin

Binding site prediction 

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