Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionE6N0W0
DateSat Apr 13 12:48:06 BST 2013
Unique Job ID2060d4b5fde3bb56

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:62.363 Y:57.197 Z:48.946
Model (left) based on template c1griA_
Top template information
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
Confidence and coverage
Confidence: 99.9% Coverage: 23%
192 residues ( 23% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
324 residues ( 39%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MCGISSRSANNTPELEPGAEPPQKSPAPKTFEDKRQDNLSKGQAELERRRRVLEEEEQRR
Secondary structure 












SS confidence 



























































Disorder  ????????????????

??








?





























Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  RAEVEKKEREEEAKKNRERQEKERQAEVERQAELERQRIIEAQREEEEKKRRLEMERRRE
Secondary structure 
SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  EDEKMRKVQMEKAKVKQMQNQKQQENERLAQRQQREKTLQFQLQALDEKVIDVEVDIGKA
Secondary structure 
SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  KEAVAEVTGFIERMRSTRDEKVARIKELQETNQKTAIESQELGHQLLQKQSAHKETTQRK
Secondary structure 
SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  SELEALRRKRDAIRKAIEDAALELSTEKEKSYNQTEILKTNKEKYKTDVYSKLVAKREEY
Secondary structure 
SS confidence 



























































Disorder 


























































?
Disorder confidence 



























































 
   .........310.........320.........330.........340.........350.........360
Sequence  RNSFELLVHAQTHARSKIGEFEAKSAPASAAPAPAPAPAPTTTNGFPANFNDAFGEFDKT
Secondary structure 






























SS confidence 



























































Disorder  ????????????????????????????????????????????????????????????
Disorder confidence 



























































 
   .........370.........380.........390.........400.........410.........420
Sequence  DASQRFDADFGATSTADPFAQIAQAPAHSKGAVDQSAFNIHDTYKCRALFAFEARSEDEL
Secondary structure 





















































SS confidence 



























































Disorder  ???????????????????????????????????????????









?
???

Disorder confidence 



























































 
   .........430.........440.........450.........460.........470.........480
Sequence  SFEPGDVIIVFQSHAAEPGWRAGQLREKVGWFPEAFVEAIAAVPTPGGDPPIQNMPPNMT
Secondary structure 






































SS confidence 



























































Disorder 





































??????????????????????
Disorder confidence 



























































 
   .........490.........500.........510.........520.........530.........540
Sequence  PSSSVDQIGVKAARKAEIAAAMGLTEGGAPPASSAPAAAAVISQCIAQFQWRARNEEDLS
Secondary structure 



















































SS confidence 



























































Disorder  ??????????????????????????????????????????











??????
Disorder confidence 



























































 
   .........550.........560.........570.........580.........590.........600
Sequence  FAKGDTIEVLEKQEMKWKGRNPAGEIGWFPKSYVKEVGATTSTTTPIVSPSKASAGAPGA
Secondary structure 




































SS confidence 



























































Disorder 




















?













????????????????????????
Disorder confidence 



























































 
   .........610.........620.........630.........640.........650.........660
Sequence  AAGAQYDVVPSDVTLQASETAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKNDEWWK
Secondary structure 












































SS confidence 



























































Disorder  ????????????????????????









???????????
?








?


Disorder confidence 



























































 
   .........670.........680.........690.........700.........710.........720
Sequence  GRCNGREGIFPANYVEISVQQAGDPTPPTQAPTPAAPPTVLCEAKVVVDFVASAPNQLGI
Secondary structure 















































SS confidence 



























































Disorder 


????







??????????????????????????????
?
????????????
Disorder confidence 



























































 
   .........730.........740.........750.........760.........770.........780
Sequence  KVGEIVKIREKSAAGWWEGELIRNGKPIAGWFPGEYVKVLEEAASPATRATAVYDYEASQ
Secondary structure 










































SS confidence 



























































Disorder  ????







???

?
??????????








?????????












Disorder confidence 



























































 
   .........790.........800.........810.........820.....
Sequence  PDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQQQ
Secondary structure 























SS confidence 












































Disorder  ?????



































????
Disorder confidence 












































 

Confidence Key
High(9)                    Low (0)
?Disordered ( 41%)
Alpha helix ( 40%)
Beta strand ( 13%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1gri chain A

3D model

Region: 625 - 823
Aligned: 192
Modelled: 199
Confidence: 99.9%
Identity: 26%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 2lqn chain A

3D model

Region: 669 - 824
Aligned: 150
Modelled: 156
Confidence: 99.9%
Identity: 29%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2l3s chain A

3D model

Region: 522 - 823
Aligned: 158
Modelled: 161
Confidence: 99.9%
Identity: 23%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 2eyz chain A

3D model

Region: 494 - 824
Aligned: 187
Modelled: 190
Confidence: 99.9%
Identity: 26%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 1ov3 chain A

3D model

Region: 694 - 824
Aligned: 124
Modelled: 131
Confidence: 99.9%
Identity: 26%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 1ng2 chain A

3D model

Region: 700 - 823
Aligned: 117
Modelled: 120
Confidence: 99.9%
Identity: 29%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2

PDB 1mv3 chain A

3D model

Region: 583 - 824
Aligned: 199
Modelled: 199
Confidence: 99.8%
Identity: 20%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 2rqr chain A

3D model

Region: 712 - 823
Aligned: 111
Modelled: 112
Confidence: 99.7%
Identity: 15%
PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex

Phyre2

PDB 2dx1 chain A

3D model

Region: 765 - 823
Aligned: 56
Modelled: 59
Confidence: 99.7%
Identity: 39%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 1udl chain A

3D model

Region: 743 - 823
Aligned: 78
Modelled: 81
Confidence: 99.7%
Identity: 41%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 1ng2 chain A domain 2

3D model

Region: 762 - 823
Aligned: 59
Modelled: 62
Confidence: 99.6%
Identity: 31%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 2kym chain A

3D model

Region: 769 - 823
Aligned: 55
Modelled: 55
Confidence: 99.6%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide

Phyre2

PDB 2jxb chain A

3D model

Region: 759 - 825
Aligned: 64
Modelled: 67
Confidence: 99.6%
Identity: 28%
PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex

Phyre2

PDB 2yt6 chain A

3D model

Region: 743 - 823
Aligned: 80
Modelled: 81
Confidence: 99.6%
Identity: 30%
PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1

Phyre2

PDB 3nmz chain D

3D model

Region: 743 - 823
Aligned: 78
Modelled: 81
Confidence: 99.6%
Identity: 29%
PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef

Phyre2

PDB 2eyy chain A

3D model

Region: 736 - 824
Aligned: 87
Modelled: 89
Confidence: 99.6%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i

Phyre2

PDB 1x6g chain A

3D model

Region: 753 - 825
Aligned: 72
Modelled: 73
Confidence: 99.6%
Identity: 18%
PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.

Phyre2

PDB 2rqv chain A

3D model

Region: 763 - 823
Aligned: 61
Modelled: 61
Confidence: 99.6%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of sh3ci domain of bem1p

Phyre2

PDB 2j06 chain B

3D model

Region: 767 - 824
Aligned: 57
Modelled: 58
Confidence: 99.6%
Identity: 26%
PDB header:signal transduction
Chain: B: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution

Phyre2

PDB 2ed1 chain A

3D model

Region: 762 - 823
Aligned: 62
Modelled: 62
Confidence: 99.6%
Identity: 40%
PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein

Phyre2
1

c1griA_
2

c2lqnA_
3

c2l3sA_
4

c2eyzA_
5

c1ov3A_
6

c1ng2A_
7

c1mv3A_
8

c2rqrA_
9

c2dx1A_
10

d1udla_
11

d1ng2a2
12

c2kymA_
13

c2jxbA_
14

c2yt6A_
15

c3nmzD_
16

c2eyyA_
17

c1x6gA_
18

c2rqvA_
19

c2j06B_
20

c2ed1A_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139



140



141



142



143



144



145



146



147



148



149



150



151



152



153



154



155



156



157



158



159



160



161



162



163



164



165



166



167



168



169



170



171



172



173



174



175



176



177



178



179



180



181



182



183



184



185



186



187



188



189



190



191



192



193



194



195



196



197



198



199



200



201



202



203



204



205



206



207



208



209



210



211



212



213



214



215



216



217



218



219



220



221



222



223



224



225



226



227



228



229



230



231



232



233



234



235



236



237



238



239



240



241



242



243



244



245



246



247



248



249



250



251



252



253



254



255



256



257



258



259



260



261



262



263



264



265



266



267



268



269



270



271



272



273



274



275



276



277



278



279



280



281



282



283



284



285



286



287



288



289



290



291



292



293



294



295



296



297



298



299



300



301



302



303



304



305



306



307



308



309



310



311



312



313



314



315



316



317



318



319



320



321



322



323



324



325



326



327



328



329



330



331



332



333



334



335



336



337



338



339



340



341



342



343



344



345



346



347



348



349



350



351



352



353



354



355



356



357



358



359



360



361



362



363



364



365



366



367



368



369



370



371



372



373



374



375



376



377



378



379



380



381



382



383



384



385



386



387



388



389



390



391



392



393



394



395



396



397



398



399



400



401



402



403



404



405



406



407



408



409



410



411



412



413



414






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1griA_



99.9 26 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
2c2lqnA_



99.9 29 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
3c2l3sA_



99.9 23 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
4c2eyzA_



99.9 26 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
5c1ov3A_



99.9 26 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
6c1ng2A_



99.9 29 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
7c1mv3A_



99.8 20 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
8c2rqrA_



99.7 15 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
9c2dx1A_



99.7 39 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
10d1udla_



99.7 41 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
11d1ng2a2



99.6 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
12c2kymA_



99.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
13c2jxbA_



99.6 28 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
14c2yt6A_



99.6 30 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
15c3nmzD_



99.6 29 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
16c2eyyA_



99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
17c1x6gA_



99.6 18 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
18c2rqvA_



99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of sh3ci domain of bem1p
19c2j06B_



99.6 26 PDB header:signal transduction
Chain: B: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution
20c2ed1A_



99.6 40 PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
21c2fpeB_



not modelled 99.6 22 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
22d1ov3a2



not modelled 99.6 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
23c2yupA_



not modelled 99.6 28 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
24c1zukA_



not modelled 99.6 28 PDB header:contractile protein
Chain: A: PDB Molecule:myosin tail region-interacting protein mti1;
PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17
25c1zlmA_



not modelled 99.6 44 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
26d1ue9a_



not modelled 99.6 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
27c2e5kA_



not modelled 99.6 26 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
28c3qwyA_



not modelled 99.6 22 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
29c2cudA_



not modelled 99.6 16 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
30c2ct3A_



not modelled 99.6 32 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
31c3rnjA_



not modelled 99.6 26 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)
32c3qwxX_



not modelled 99.6 22 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
33c1x6bA_



not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
34c2egcA_



not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the fifth sh3 domain from human2 kiaa0418 protein
35c2lj0A_



not modelled 99.6 30 PDB header:signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: the third sh3 domain of r85fl
36c2d8jA_



not modelled 99.5 32 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh3 domain of fyn-related kinase
37c2lcsA_



not modelled 99.5 32 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:nap1-binding protein 2;
PDBTitle: yeast nbp2p sh3 domain in complex with a peptide from ste20p
38d1k4us_



not modelled 99.5 37 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
39d1phta_



not modelled 99.5 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
40c2ysqA_



not modelled 99.5 39 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
41d1i1ja_



not modelled 99.5 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
42c2yunA_



not modelled 99.5 37 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
43c2oi3A_



not modelled 99.5 29 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
44d1cska_



not modelled 99.5 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
45c2l0aA_



not modelled 99.5 42 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
46c2xmfA_



not modelled 99.5 36 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
47c1zuyB_



not modelled 99.5 38 PDB header:contractile protein
Chain: B: PDB Molecule:myosin-5 isoform;
PDBTitle: high-resolution structure of yeast myo5 sh3 domain
48d1wiea_



not modelled 99.5 22 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
49c1x2qA_



not modelled 99.5 44 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
50c2df6A_



not modelled 99.5 39 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
51d1uj0a_



not modelled 99.5 47 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
52c2m0yA_



not modelled 99.5 28 PDB header:apoptosis
Chain: A: PDB Molecule:dedicator of cytokinesis protein 1;
PDBTitle: solution structure of the sh3 domain of dock180
53c2cucA_



not modelled 99.5 31 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2
54c2yuoA_



not modelled 99.5 32 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
55c1yn8E_



not modelled 99.5 32 PDB header:unknown function
Chain: E: PDB Molecule:nap1-binding protein 2;
PDBTitle: sh3 domain of yeast nbp2
56c2egeA_



not modelled 99.5 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein kiaa1666;
PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
57c2d8hA_



not modelled 99.5 29 PDB header:unknown function
Chain: A: PDB Molecule:sh3yl1 protein;
PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1
58c1wx6A_



not modelled 99.5 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:cytoplasmic protein nck2;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2
59c2enmA_



not modelled 99.5 29 PDB header:endocytosis
Chain: A: PDB Molecule:sorting nexin-9;
PDBTitle: solution structure of the sh3 domain from mouse sorting2 nexin-9
60c2cubA_



not modelled 99.5 32 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
61c4esrB_



not modelled 99.5 38 PDB header:protein binding
Chain: B: PDB Molecule:jouberin;
PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors
62d1jo8a_



not modelled 99.5 44 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
63c2ekhA_



not modelled 99.5 28 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
64c2epdA_



not modelled 99.5 27 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
65d1uuea_



not modelled 99.5 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
66c2dmoA_



not modelled 99.5 20 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
67c2nwmA_



not modelled 99.5 30 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
68c2kt1A_



not modelled 99.5 30 PDB header:protein binding
Chain: A: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: solution nmr structure of the sh3 domain from the p85beta2 subunit of phosphatidylinositol 3-kinase from h.sapiens,3 northeast structural genomics consortium target hr5531e
69d1gcqa_



not modelled 99.5 41 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
70c2ke9A_



not modelled 99.5 29 PDB header:protein binding
Chain: A: PDB Molecule:caskin-2;
PDBTitle: nmr solution structure of the caskin sh3 domain
71c2ebpA_



not modelled 99.5 28 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
72c1x43A_



not modelled 99.5 23 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
73c2djqA_



not modelled 99.5 32 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
74c4glmD_



not modelled 99.5 33 PDB header:signaling protein
Chain: D: PDB Molecule:dynamin-binding protein;
PDBTitle: crystal structure of the sh3 domain of dnmbp protein [homo sapiens]
75d1oeba_



not modelled 99.5 47 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
76d1uffa_



not modelled 99.5 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
77c2csqA_



not modelled 99.5 29 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
78d1ckaa_



not modelled 99.5 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
79c2jteA_



not modelled 99.5 26 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: third sh3 domain of cd2ap
80c4afzC_



not modelled 99.5 32 PDB header:hydrolase/de novo protein
Chain: C: PDB Molecule:fynomer;
PDBTitle: human chymase - fynomer complex
81c2i0nA_



not modelled 99.5 33 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
82c1bb9A_



not modelled 99.5 32 PDB header:transferase
Chain: A: PDB Molecule:amphiphysin 2;
PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2
83d1bb9a_



not modelled 99.5 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
84d1utia_



not modelled 99.5 50 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
85c2dlpA_



not modelled 99.5 26 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
86c2dnuA_



not modelled 99.5 26 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
87c2rf0D_



not modelled 99.5 40 PDB header:transferase
Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10;
PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
88d1gl5a_



not modelled 99.5 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
89c2dl4A_



not modelled 99.5 31 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
90d1k9aa1



not modelled 99.5 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
91c2ed0A_



not modelled 99.5 33 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
92c2dilA_



not modelled 99.5 34 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
93d2iima1



not modelled 99.5 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
94d1wlpb2



not modelled 99.5 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
95c2bz8B_



not modelled 99.5 37 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
96d1fmka1



not modelled 99.5 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
97c2eyxA_



not modelled 99.5 22 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
98d1spka_



not modelled 99.5 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
99d1sema_



not modelled 99.5 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
100c2d1xD_



not modelled 99.5 40 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
101c1zx6A_



not modelled 99.5 34 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
102c1x2pA_



not modelled 99.5 30 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 2;
PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
103d1gria2



not modelled 99.5 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
104c2dl3A_



not modelled 99.5 25 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
105d1pwta_



not modelled 99.5 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
106d1u06a1



not modelled 99.5 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
107c2dl8A_



not modelled 99.5 27 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
108d2v1ra1



not modelled 99.5 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
109c2lx7A_



not modelled 99.5 29 PDB header:protein binding
Chain: A: PDB Molecule:growth arrest-specific protein 7;
PDBTitle: solution nmr structure of sh3 domain of growth arrest-specific protein2 7 (gas7) (fragment 1-60) from homo sapiens, northeast structural3 genomics consortium (nesg) target hr8574a
110d1jqqa_



not modelled 99.5 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
111c1w70A_



not modelled 99.5 35 PDB header:sh3 domain
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
112c2dbkA_



not modelled 99.5 21 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
113c2ct4A_



not modelled 99.5 17 PDB header:signaling protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: solution strutcure of the sh3 domain of the cdc42-2 interacting protein 4
114d1shfa_



not modelled 99.5 39 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
115d1e6ga_



not modelled 99.5 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
116c3cqtA_



not modelled 99.5 35 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: n53i v55l mutant of fyn sh3 domain
117c2egaA_



not modelled 99.5 25 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein
118c1z9zA_



not modelled 99.5 37 PDB header:structural protein
Chain: A: PDB Molecule:cytoskeleton assembly control protein sla1;
PDBTitle: crystal structure of yeast sla1 sh3 domain 3
119c2js0A_



not modelled 99.5 38 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of second sh3 domain of adaptor nck
120d1arka_



not modelled 99.5 36 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite