Phyre 2 Results for Q9JK95

Email	l.a.kelley@imperial.ac.uk
Description	Q9JK95
Date	Wed Jul 10 14:03:56 BST 2013
Unique Job ID	89f945e39a9ae1d1
Sequence	MLRCGLACER ... Download FASTA

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:36.389 Y:35.890 Z:47.127

Model (left) based on template d1j4na_

Top template information

Fold:Aquaporin-like
Superfamily:Aquaporin-like
Family:Aquaporin-like

Confidence and coverage

Confidence:

17.5%

Coverage:

54%

105 residues ( 54% of your sequence) have been modelled with 17.5% confidence by the single highest scoring template.

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3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M L R C G L A C E R C R W I L P L L L L S A I A F D I I A L A G R G W L Q S S N H I Q T S S L W W R C F D E G G G S G S

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ? ? ?
?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence Y D D G C Q S L M E Y A W G R A A A A T L F C G F I I L C I C F I L S F F A L C G P Q M L V F L R V I G G L L A L A A I

Secondary structure

SS confidence

Disorder ? ?
?
? ?
? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence F Q I I S L V I Y P V K Y T Q T F R L H D N P A V N Y I Y N W A Y G F G W A A T I I L I G C S F F F C C L P N Y E D D L

Secondary structure

SS confidence

Disorder
? ?

Disorder confidence

. . . . . . . . . 190 . . .

Sequence L G A A K P R Y F Y P P A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 18%)

Alpha helix ( 69%)

Beta strand ( 3%)

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1j4n chain A

Region: 78 - 185
Aligned: 105
Modelled: 108
Confidence: 17.5%
Identity: 11%
Fold: Aquaporin-like
Superfamily: Aquaporin-like
Family: Aquaporin-like

Phyre2

PDB 2kse chain A

Region: 10 - 45
Aligned: 34
Modelled: 36
Confidence: 14.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:sensor protein qsec;
PDBTitle: backbone structure of the membrane domain of e. coli histidine kinase2 receptor qsec, center for structures of membrane proteins (csmp)3 target 4311c

Phyre2

PDB 2pm5 chain B

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 11.6%
Identity: 38%
PDB header:antimicrobial protein
Chain: B: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha
PDBTitle: human alpha-defensin 1 derivative (hnp1)

Phyre2

PDB 2pm5 chain A

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 11.6%
Identity: 38%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha
PDBTitle: human alpha-defensin 1 derivative (hnp1)

Phyre2

PDB 2pm1 chain A

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 11.5%
Identity: 38%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1)
PDBTitle: derivative of human alpha-defensin 1 (hnp1)

Phyre2

PDB 1dtx chain A

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 10.9%
Identity: 13%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1shp chain A

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 10.0%
Identity: 13%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1p2j chain I

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 9.3%
Identity: 30%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 4b0f chain E

Region: 172 - 178
Aligned: 7
Modelled: 7
Confidence: 9.2%
Identity: 86%
PDB header:immune system
Chain: E: PDB Molecule:c4b-binding protein alpha chain;
PDBTitle: heptameric core complex structure of c4b-binding (c4bp)2 protein from human

Phyre2

PDB 1dtk chain A

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 8.7%
Identity: 13%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1bf0 chain A

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 8.7%
Identity: 4%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1jc6 chain A

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 8.5%
Identity: 22%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1ld6 chain A

Region: 171 - 192
Aligned: 22
Modelled: 22
Confidence: 8.4%
Identity: 36%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1bpi chain A

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 8.4%
Identity: 30%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1zr0 chain B domain 1

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 8.3%
Identity: 26%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 3rko chain F

Region: 68 - 180
Aligned: 113
Modelled: 113
Confidence: 8.0%
Identity: 18%
PDB header:oxidoreductase
Chain: F: PDB Molecule:nadh-quinone oxidoreductase subunit j;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution

Phyre2

PDB 1pb5 chain A

Region: 171 - 184
Aligned: 13
Modelled: 14
Confidence: 7.7%
Identity: 38%
Fold: Notch domain
Superfamily: Notch domain
Family: Notch domain

Phyre2

PDB 1yc0 chain I

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 7.6%
Identity: 26%
PDB header:hydrolase/inhibitor
Chain: I: PDB Molecule:kunitz-type protease inhibitor 1;
PDBTitle: short form hgfa with first kunitz domain from hai-1

Phyre2

PDB 4j05 chain A

Region: 71 - 187
Aligned: 104
Modelled: 117
Confidence: 7.6%
Identity: 12%
PDB header:transport protein
Chain: A: PDB Molecule:phosphate transporter;
PDBTitle: crystal structure of a eukaryotic phosphate transporter

Phyre2

PDB 1aap chain A

Region: 171 - 193
Aligned: 23
Modelled: 23
Confidence: 7.4%
Identity: 17%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	L	R	C	G	L	A	C	E	R	C	R	W	I	L	P	L	L	L	L	S	A	I	A	F	D	I	I	A	L	A	G	R	G	W	L	Q	S	S	N	H	I	Q	T	S	S	L	W	W	R	C	F	D	E	G	G	G	S	G	S
Secondary structure
SS confidence
Disorder	?	?	?	?	?																																		?	?	?	?		?									?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	Y	D	D	G	C	Q	S	L	M	E	Y	A	W	G	R	A	A	A	A	T	L	F	C	G	F	I	I	L	C	I	C	F	I	L	S	F	F	A	L	C	G	P	Q	M	L	V	F	L	R	V	I	G	G	L	L	A	L	A	A	I
Secondary structure
SS confidence
Disorder	?	?						?			?	?																																?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	F	Q	I	I	S	L	V	I	Y	P	V	K	Y	T	Q	T	F	R	L	H	D	N	P	A	V	N	Y	I	Y	N	W	A	Y	G	F	G	W	A	A	T	I	I	L	I	G	C	S	F	F	F	C	C	L	P	N	Y	E	D	D	L
Secondary structure
SS confidence
Disorder																			?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.
Sequence	L	G	A	A	K	P	R	Y	F	Y	P	P	A
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?
Disorder confidence