Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ8CFU8
DateTue Jul 30 12:57:00 BST 2013
Unique Job ID9e80d9b5cf62af12
SequenceMFQRFTSLFF ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:24.132 Y:22.489 Z:14.378
Model (left) based on template d2o5aa1
Top template information
Fold:Nucleotidyltransferase
Superfamily:Nucleotidyltransferase
Family:Iojap/YbeB-like
Confidence and coverage
Confidence: 43.7% Coverage: 7%
15 residues ( 7% of your sequence) have been modelled with 43.7% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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Warning: 60% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MFQRFTSLFFNTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQDSYTAPPDPGASPAPAGRP
Secondary structure 
SS confidence 
Disorder  ?
?
?????????
???
???????????????????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  PPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESG
Secondary structure 
SS confidence 
Disorder  ?????????
???????????????
??????????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  PPSPHPEAALPDQDLSDGELAPALREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRA
Secondary structure 
SS confidence 
Disorder  ?????????????????????????????????????
??
Disorder confidence 
 
   .........190.........200.........210.........220.
Sequence  ERHTLSAKVLQRQNRARESRSRRPKHQGSFIYQPCQRQFNY
Secondary structure 
SS confidence 
Disorder  ??????
???????????????
??????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 60%)
Alpha helix ( 43%)
Beta strand ( 8%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2o5a chain A domain 1

3D model

Region: 28 - 42
Aligned: 15
Modelled: 15
Confidence: 43.7%
Identity: 47%
Fold: Nucleotidyltransferase
Superfamily: Nucleotidyltransferase
Family: Iojap/YbeB-like

Phyre2

PDB 3ups chain A

3D model

Region: 28 - 42
Aligned: 15
Modelled: 15
Confidence: 42.7%
Identity: 27%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:iojap-like protein;
PDBTitle: crystal structure of iojap-like protein from zymomonas mobilis

Phyre2

PDB 2id1 chain A domain 1

3D model

Region: 28 - 42
Aligned: 15
Modelled: 15
Confidence: 41.2%
Identity: 33%
Fold: Nucleotidyltransferase
Superfamily: Nucleotidyltransferase
Family: Iojap/YbeB-like

Phyre2

PDB 2biw chain C

3D model

Region: 29 - 74
Aligned: 46
Modelled: 45
Confidence: 36.8%
Identity: 26%
PDB header:oxidoreductase
Chain: C: PDB Molecule:apocarotenoid-cleaving oxygenase;
PDBTitle: crystal structure of apocarotenoid cleavage oxygenase from2 synechocystis, native enzyme

Phyre2

PDB 1wfw chain A

3D model

Region: 29 - 66
Aligned: 38
Modelled: 38
Confidence: 32.8%
Identity: 18%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 3qsq chain A

3D model

Region: 7 - 77
Aligned: 71
Modelled: 71
Confidence: 31.4%
Identity: 15%
PDB header:viral protein
Chain: A: PDB Molecule:capsid polyprotein;
PDBTitle: crystal structure of the projection domain of the human astrovirus2 capsid protein

Phyre2

PDB 3npe chain A

3D model

Region: 22 - 49
Aligned: 28
Modelled: 28
Confidence: 29.6%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:9-cis-epoxycarotenoid dioxygenase 1, chloroplastic;
PDBTitle: structure of vp14 in complex with oxygen

Phyre2

PDB 3fsn chain A

3D model

Region: 29 - 38
Aligned: 10
Modelled: 10
Confidence: 24.2%
Identity: 30%
PDB header:isomerase
Chain: A: PDB Molecule:retinal pigment epithelium-specific 65 kda protein;
PDBTitle: crystal structure of rpe65 at 2.14 angstrom resolution

Phyre2

PDB 3m1h chain B

3D model

Region: 25 - 76
Aligned: 52
Modelled: 52
Confidence: 21.5%
Identity: 21%
PDB header:cell invasion
Chain: B: PDB Molecule:lysine specific cysteine protease;
PDBTitle: crystal structure analysis of the k3 cleaved adhesin domain of lys-2 gingipain (kgp) from porphyromonas gingivalis w83

Phyre2

PDB 1zcz chain A domain 1

3D model

Region: 95 - 106
Aligned: 12
Modelled: 12
Confidence: 18.1%
Identity: 25%
Fold: Methylglyoxal synthase-like
Superfamily: Methylglyoxal synthase-like
Family: Inosicase

Phyre2

PDB 3r8k chain B

3D model

Region: 1 - 34
Aligned: 34
Modelled: 34
Confidence: 17.3%
Identity: 12%
PDB header:apoptosis
Chain: B: PDB Molecule:heme-binding protein 2;
PDBTitle: crystal structure of human soul protein (hexagonal form)

Phyre2

PDB 3hxr chain A

3D model

Region: 31 - 43
Aligned: 13
Modelled: 13
Confidence: 16.4%
Identity: 23%
PDB header:structural protein
Chain: A: PDB Molecule:nucleoporin nup120;
PDBTitle: nucleoporin nup120 from s.cerevisiae (aa 1-757)

Phyre2

PDB 2gov chain A domain 1

3D model

Region: 1 - 34
Aligned: 34
Modelled: 34
Confidence: 14.8%
Identity: 3%
Fold: Probable bacterial effector-binding domain
Superfamily: Probable bacterial effector-binding domain
Family: SOUL heme-binding protein

Phyre2

PDB 2cfu chain A domain 2

3D model

Region: 25 - 43
Aligned: 19
Modelled: 19
Confidence: 14.3%
Identity: 16%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Alkylsulfatase-like

Phyre2

PDB 3fka chain D

3D model

Region: 24 - 40
Aligned: 17
Modelled: 17
Confidence: 13.9%
Identity: 18%
PDB header:unknown function
Chain: D: PDB Molecule:uncharacterized ntf-2 like protein;
PDBTitle: crystal structure of a ntf-2 like protein of unknown function2 (spo1084) from silicibacter pomeroyi dss-3 at 1.69 a resolution

Phyre2

PDB 1q1o chain A

3D model

Region: 30 - 43
Aligned: 14
Modelled: 14
Confidence: 13.5%
Identity: 14%
Fold: beta-Grasp (ubiquitin-like)
Superfamily: CAD & PB1 domains
Family: PB1 domain

Phyre2

PDB 3alz chain B

3D model

Region: 20 - 41
Aligned: 22
Modelled: 22
Confidence: 13.5%
Identity: 23%
PDB header:viral protein/membrane protein
Chain: B: PDB Molecule:cdw150;
PDBTitle: crystal structure of the measles virus hemagglutinin bound to its2 cellular receptor slam (form i)

Phyre2

PDB 3duk chain D

3D model

Region: 24 - 40
Aligned: 17
Modelled: 17
Confidence: 13.4%
Identity: 12%
PDB header:unknown function
Chain: D: PDB Molecule:ntf2-like protein of unknown function;
PDBTitle: crystal structure of a ntf2-like protein of unknown function2 (mfla_0564) from methylobacillus flagellatus kt at 2.200 a resolution

Phyre2

PDB 4eoy chain B

3D model

Region: 8 - 45
Aligned: 38
Modelled: 38
Confidence: 13.3%
Identity: 13%
PDB header:transport protein
Chain: B: PDB Molecule:microtubule-associated protein 1 light chain 3;
PDBTitle: plasmodium falciparum atg8 in complex with plasmodium falciparum atg32 peptide

Phyre2

PDB 3kub chain A

3D model

Region: 32 - 110
Aligned: 71
Modelled: 79
Confidence: 13.0%
Identity: 17%
PDB header:oxidoreductase
Chain: A: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of aspartate semi-aldehyde dehydrogenase complexed2 with glycerol and phosphate of mycobacterium tuberculosis h37rv

Phyre2
1
d2o5aa1
2
c3upsA_
3
d2id1a1
4
c2biwC_
5
d1wfwa_
6
c3qsqA_
7
c3npeA_
8
c3fsnA_
9
c3m1hB_
10
d1zcza1
11
c3r8kB_
12
c3hxrA_
13
d2gova1
14
d2cfua2
15
c3fkaD_
16
d1q1oa_
17
c3alzB_
18
c3dukD_
19
c4eoyB_
20
c3kubA_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2o5aa1
43.7 47 Fold:Nucleotidyltransferase
Superfamily:Nucleotidyltransferase
Family:Iojap/YbeB-like
2c3upsA_
42.7 27 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:iojap-like protein;
PDBTitle: crystal structure of iojap-like protein from zymomonas mobilis
3d2id1a1
41.2 33 Fold:Nucleotidyltransferase
Superfamily:Nucleotidyltransferase
Family:Iojap/YbeB-like
4c2biwC_
36.8 26 PDB header:oxidoreductase
Chain: C: PDB Molecule:apocarotenoid-cleaving oxygenase;
PDBTitle: crystal structure of apocarotenoid cleavage oxygenase from2 synechocystis, native enzyme
5d1wfwa_
32.8 18 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
6c3qsqA_
31.4 15 PDB header:viral protein
Chain: A: PDB Molecule:capsid polyprotein;
PDBTitle: crystal structure of the projection domain of the human astrovirus2 capsid protein
7c3npeA_
29.6 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:9-cis-epoxycarotenoid dioxygenase 1, chloroplastic;
PDBTitle: structure of vp14 in complex with oxygen
8c3fsnA_
24.2 30 PDB header:isomerase
Chain: A: PDB Molecule:retinal pigment epithelium-specific 65 kda protein;
PDBTitle: crystal structure of rpe65 at 2.14 angstrom resolution
9c3m1hB_
21.5 21 PDB header:cell invasion
Chain: B: PDB Molecule:lysine specific cysteine protease;
PDBTitle: crystal structure analysis of the k3 cleaved adhesin domain of lys-2 gingipain (kgp) from porphyromonas gingivalis w83
10d1zcza1
18.1 25 Fold:Methylglyoxal synthase-like
Superfamily:Methylglyoxal synthase-like
Family:Inosicase
11c3r8kB_
17.3 12 PDB header:apoptosis
Chain: B: PDB Molecule:heme-binding protein 2;
PDBTitle: crystal structure of human soul protein (hexagonal form)
12c3hxrA_
16.4 23 PDB header:structural protein
Chain: A: PDB Molecule:nucleoporin nup120;
PDBTitle: nucleoporin nup120 from s.cerevisiae (aa 1-757)
13d2gova1
14.8 3 Fold:Probable bacterial effector-binding domain
Superfamily:Probable bacterial effector-binding domain
Family:SOUL heme-binding protein
14d2cfua2
14.3 16 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Alkylsulfatase-like
15c3fkaD_
13.9 18 PDB header:unknown function
Chain: D: PDB Molecule:uncharacterized ntf-2 like protein;
PDBTitle: crystal structure of a ntf-2 like protein of unknown function2 (spo1084) from silicibacter pomeroyi dss-3 at 1.69 a resolution
16d1q1oa_
13.5 14 Fold:beta-Grasp (ubiquitin-like)
Superfamily:CAD & PB1 domains
Family:PB1 domain
17c3alzB_
13.5 23 PDB header:viral protein/membrane protein
Chain: B: PDB Molecule:cdw150;
PDBTitle: crystal structure of the measles virus hemagglutinin bound to its2 cellular receptor slam (form i)
18c3dukD_
13.4 12 PDB header:unknown function
Chain: D: PDB Molecule:ntf2-like protein of unknown function;
PDBTitle: crystal structure of a ntf2-like protein of unknown function2 (mfla_0564) from methylobacillus flagellatus kt at 2.200 a resolution
19c4eoyB_
13.3 13 PDB header:transport protein
Chain: B: PDB Molecule:microtubule-associated protein 1 light chain 3;
PDBTitle: plasmodium falciparum atg8 in complex with plasmodium falciparum atg32 peptide
20c3kubA_
13.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of aspartate semi-aldehyde dehydrogenase complexed2 with glycerol and phosphate of mycobacterium tuberculosis h37rv
21c2zpnB_
not modelled 11.4 23 PDB header:protein transport
Chain: B: PDB Molecule:autophagy-related protein 8;
PDBTitle: the crystal structure of saccharomyces cerevisiae atg8-2 atg19(412-415) complex
22c2yheD_
not modelled 11.3 16 PDB header:hydrolase
Chain: D: PDB Molecule:sec-alkyl sulfatase;
PDBTitle: structure determination of the stereoselective inverting2 sec-alkylsulfatase pisa1 from pseudomonas sp.
23c2cfuA_
not modelled 11.2 16 PDB header:hydrolase
Chain: A: PDB Molecule:sdsa1;
PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid.
24d1pqsa_
not modelled 10.3 14 Fold:beta-Grasp (ubiquitin-like)
Superfamily:CAD & PB1 domains
Family:PB1 domain
25d1sgva2
not modelled 10.3 27 Fold:Pseudouridine synthase
Superfamily:Pseudouridine synthase
Family:Pseudouridine synthase II TruB
26c3n0kA_
not modelled 10.0 19 PDB header:hydrolase inhibitor
Chain: A: PDB Molecule:serine protease inhibitor 1;
PDBTitle: proteinase inhibitor from coprinopsis cinerea
27c1xk5A_
not modelled 9.7 30 PDB header:transport protein
Chain: A: PDB Molecule:snurportin-1;
PDBTitle: crystal structure of the m3g-cap-binding domain of2 snurportin1 in complex with a m3gpppg-cap dinucleotide
28c1zczA_
not modelled 9.2 25 PDB header:transferase/hydrolase
Chain: A: PDB Molecule:bifunctional purine biosynthesis protein purh;
PDBTitle: crystal structure of phosphoribosylaminoimidazolecarboxamide2 formyltransferase / imp cyclohydrolase (tm1249) from thermotoga3 maritima at 1.88 a resolution
29c1plpA_
not modelled 9.1 18 PDB header:membrane protein
Chain: A: PDB Molecule:phospholamban;
PDBTitle: solution structure of the cytoplasmic domain of2 phospholamban
30d3d32a1
not modelled 8.9 29 Fold:beta-Grasp (ubiquitin-like)
Superfamily:Ubiquitin-like
Family:GABARAP-like
31d1oa8a_
not modelled 8.9 26 Fold:AXH domain
Superfamily:AXH domain
Family:AXH domain
32c3nrlB_
not modelled 8.9 27 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein rumgna_01417;
PDBTitle: crystal structure of protein rumgna_01417 from ruminococcus gnavus,2 northeast structural genomics consortium target ugr76
33c3s63B_
not modelled 8.7 71 PDB header:lipid binding protein
Chain: B: PDB Molecule:saposin-like protein;
PDBTitle: saposin-like protein na-slp-1
34c2gp4B_
not modelled 8.5 11 PDB header:lyase
Chain: B: PDB Molecule:6-phosphogluconate dehydratase;
PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis
35d1p5dx4
not modelled 8.2 29 Fold:TBP-like
Superfamily:Phosphoglucomutase, C-terminal domain
Family:Phosphoglucomutase, C-terminal domain
36c2istA_
not modelled 8.2 19 PDB header:isomerase
Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d;
PDBTitle: crystal structure of rlud from e. coli
37d2zjda1
not modelled 8.1 23 Fold:beta-Grasp (ubiquitin-like)
Superfamily:Ubiquitin-like
Family:GABARAP-like
38d1k12a_
not modelled 8.0 24 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:Fucose binding lectin
39c2gp4A_
not modelled 7.6 11 PDB header:lyase
Chain: A: PDB Molecule:6-phosphogluconate dehydratase;
PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis
40c2qz9B_
not modelled 7.4 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase2 ii from vibrio cholerae
41c2i82D_
not modelled 7.4 13 PDB header:lyase/rna
Chain: D: PDB Molecule:ribosomal large subunit pseudouridine synthase a;
PDBTitle: crystal structure of pseudouridine synthase rlua: indirect2 sequence readout through protein-induced rna structure
42c1qyuA_
not modelled 7.3 19 PDB header:lyase
Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d;
PDBTitle: structure of the catalytic domain of 23s rrna pseudouridine2 synthase rlud
43d1eo6a_
not modelled 6.3 24 Fold:beta-Grasp (ubiquitin-like)
Superfamily:Ubiquitin-like
Family:GABARAP-like
44c2gz3D_
not modelled 6.3 20 PDB header:oxidoreductase
Chain: D: PDB Molecule:aspartate beta-semialdehyde dehydrogenase;
PDBTitle: structure of aspartate semialdehyde dehydrogenase (asadh) from2 streptococcus pneumoniae complexed with nadp and aspartate-3 semialdehyde
45c3vvwB_
not modelled 6.2 16 PDB header:protein transport
Chain: B: PDB Molecule:microtubule-associated proteins 1a/1b light chain 3c;
PDBTitle: ndp52 in complex with lc3c
46d1wj6a_
not modelled 6.0 30 Fold:beta-Grasp (ubiquitin-like)
Superfamily:CAD & PB1 domains
Family:PB1 domain
47c2kpmA_
not modelled 5.6 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution nmr structure of uncharacterized protein from gene2 locus ne0665 of nitrosomonas europaea. northeast structural3 genomics target ner103a
48c3am2A_
not modelled 5.5 24 PDB header:toxin
Chain: A: PDB Molecule:heat-labile enterotoxin b chain;
PDBTitle: clostridium perfringens enterotoxin
49c3mxuA_
not modelled 5.3 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycine cleavage system h protein;
PDBTitle: crystal structure of glycine cleavage system protein h from bartonella2 henselae
50d1ee8a2
not modelled 5.2 32 Fold:N-terminal domain of MutM-like DNA repair proteins
Superfamily:N-terminal domain of MutM-like DNA repair proteins
Family:N-terminal domain of MutM-like DNA repair proteins
51c2m65A_
not modelled 5.2 31 PDB header:hydrolase
Chain: A: PDB Molecule:probable dna dc->du-editing enzyme apobec-3a;
PDBTitle: nmr structure of human restriction factor apobec3a
52c3metB_
not modelled 5.2 20 PDB header:transcription
Chain: B: PDB Molecule:saga-associated factor 29 homolog;
PDBTitle: crystal structure of sgf29 in complex with h3k4me2
53d2gpia1
not modelled 5.1 25 Fold:Shew3726-like
Superfamily:Shew3726-like
Family:Shew3726-like
54c4esrB_
not modelled 5.0 6 PDB header:protein binding
Chain: B: PDB Molecule:jouberin;
PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors

Binding site prediction 

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If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite