Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ5F267
DateWed Jul 10 14:18:19 BST 2013
Unique Job IDc7eba2d3692eca70
SequenceMVHPPPPPPR ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:18.416 Y:13.708 Z:15.901
Model (left) based on template d2ok5a4
Top template information
Fold:Complement control module/SCR domain
Superfamily:Complement control module/SCR domain
Family:Complement control module/SCR domain
Confidence and coverage
Confidence: 77.9% Coverage: 3%
13 residues ( 3% of your sequence) have been modelled with 77.9% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MVHPPPPPPRLLLVALVGLLSLREVVAEPAEEAGTPCPEGLWPVPPQVLPRVTYTQVSQG
Secondary structure 
SS confidence 
Disorder  ??????
?
??
?
????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  QAEGIAFFYHPCAHPWLKLQLALLAHLYVAKPTLIPDFSLTWDRPLVLTAWGTALELAWI
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  EPAWVAHWLKRQRRRKQRKSVWFLSDNLFGPTPTMPASRRGKLCGRRCVQAPTLAFALRS
Secondary structure 
SS confidence 
Disorder 
???????
???
??
????????????
?????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  WRPPGAQVTSRGSGRSSISVVKRRGLRAALGLQSTPPGLRVSLASSQSLKAQQLTLGTSS
Secondary structure 
SS confidence 
Disorder  ????????????????????????????????????????????????????????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  VAPVSLTTGGPGGNGRSRTEAQMPSGQGNHGGCACPGQVSPAPRAAGPPRVARGPTPRTE
Secondary structure 
SS confidence 
Disorder  ???????????????????????????????????????????????????????????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  EAAWAAMALTFLLVLLTLATLCTRLHRNFRRSESIYWGPTADSQDTVAALLKRRLPLPSR
Secondary structure 
SS confidence 
Disorder 
??
??????
Disorder confidence 
 
   .........370.........380.....
Sequence  RIKRSRRRPLLPPTPDSGPDSESSD
Secondary structure 
SS confidence 
Disorder 
??????
?
???????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 50%)
Alpha helix ( 43%)
Beta strand ( 4%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2ok5 chain A domain 4

3D model

Region: 35 - 47
Aligned: 13
Modelled: 13
Confidence: 77.9%
Identity: 46%
Fold: Complement control module/SCR domain
Superfamily: Complement control module/SCR domain
Family: Complement control module/SCR domain

Phyre2

PDB 1k3r chain A domain 2

3D model

Region: 266 - 314
Aligned: 24
Modelled: 24
Confidence: 74.8%
Identity: 42%
Fold: alpha/beta knot
Superfamily: alpha/beta knot
Family: Hypothetical protein MTH1 (MT0001), dimerisation domain

Phyre2

PDB 1k3r chain A

3D model

Region: 298 - 313
Aligned: 16
Modelled: 16
Confidence: 58.6%
Identity: 44%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved protein mt0001;
PDBTitle: crystal structure of the methyltransferase with a knot from2 methanobacterium thermoautotrophicum

Phyre2

PDB 1b93 chain A

3D model

Region: 56 - 93
Aligned: 38
Modelled: 38
Confidence: 56.5%
Identity: 18%
Fold: Methylglyoxal synthase-like
Superfamily: Methylglyoxal synthase-like
Family: Methylglyoxal synthase, MgsA

Phyre2

PDB 1vmd chain A

3D model

Region: 56 - 93
Aligned: 38
Modelled: 38
Confidence: 26.6%
Identity: 13%
Fold: Methylglyoxal synthase-like
Superfamily: Methylglyoxal synthase-like
Family: Methylglyoxal synthase, MgsA

Phyre2

PDB 2fwt chain A

3D model

Region: 37 - 64
Aligned: 28
Modelled: 28
Confidence: 23.9%
Identity: 21%
PDB header:electron transport
Chain: A: PDB Molecule:dhc, diheme cytochrome c;
PDBTitle: crystal structure of dhc purified from rhodobacter2 sphaeroides

Phyre2

PDB 4a8x chain B

3D model

Region: 325 - 344
Aligned: 20
Modelled: 20
Confidence: 23.2%
Identity: 30%
PDB header:transcription
Chain: B: PDB Molecule:hook-like, isoform a;
PDBTitle: structure of the core asap complex

Phyre2

PDB 3eop chain B

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 22.4%
Identity: 50%
PDB header:unknown function
Chain: B: PDB Molecule:thymocyte nuclear protein 1;
PDBTitle: crystal structure of the duf55 domain of human thymocyte nuclear2 protein 1

Phyre2

PDB 2gbs chain A domain 1

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 20.4%
Identity: 40%
Fold: PUA domain-like
Superfamily: PUA domain-like
Family: Atu2648/PH1033-like

Phyre2

PDB 1zce chain A domain 1

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 19.0%
Identity: 40%
Fold: PUA domain-like
Superfamily: PUA domain-like
Family: Atu2648/PH1033-like

Phyre2

PDB 2g2x chain A domain 1

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 18.8%
Identity: 40%
Fold: PUA domain-like
Superfamily: PUA domain-like
Family: Atu2648/PH1033-like

Phyre2

PDB 2ar1 chain A domain 1

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 18.2%
Identity: 30%
Fold: PUA domain-like
Superfamily: PUA domain-like
Family: Atu2648/PH1033-like

Phyre2

PDB 2eve chain A domain 1

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 17.4%
Identity: 40%
Fold: PUA domain-like
Superfamily: PUA domain-like
Family: Atu2648/PH1033-like

Phyre2

PDB 2dky chain A domain 1

3D model

Region: 117 - 131
Aligned: 15
Modelled: 15
Confidence: 16.6%
Identity: 33%
Fold: SAM domain-like
Superfamily: SAM/Pointed domain
Family: Variant SAM domain

Phyre2

PDB 3u99 chain A

3D model

Region: 37 - 64
Aligned: 28
Modelled: 28
Confidence: 15.9%
Identity: 18%
PDB header:electron transport
Chain: A: PDB Molecule:diheme cytochrome c;
PDBTitle: the experimental x-ray structure of the new diheme cytochrome type c2 from shewanella baltica os155 sb-dhc

Phyre2

PDB 1y5i chain A domain 1

3D model

Region: 56 - 70
Aligned: 15
Modelled: 15
Confidence: 14.4%
Identity: 40%
Fold: Double psi beta-barrel
Superfamily: ADC-like
Family: Formate dehydrogenase/DMSO reductase, C-terminal domain

Phyre2

PDB 2k8q chain A

3D model

Region: 94 - 110
Aligned: 17
Modelled: 17
Confidence: 12.4%
Identity: 29%
PDB header:structural protein
Chain: A: PDB Molecule:protein shq1;
PDBTitle: nmr structure of shq1p n-terminal domain

Phyre2

PDB 3eud chain E

3D model

Region: 93 - 110
Aligned: 18
Modelled: 17
Confidence: 12.2%
Identity: 28%
PDB header:nuclear protein
Chain: E: PDB Molecule:protein shq1;
PDBTitle: structure of the cs domain of the essential h/aca rnp2 assembly protein shq1p

Phyre2

PDB 1w4m chain A

3D model

Region: 123 - 158
Aligned: 36
Modelled: 36
Confidence: 11.4%
Identity: 19%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: DEP domain

Phyre2

PDB 2jy0 chain A

3D model

Region: 300 - 319
Aligned: 20
Modelled: 20
Confidence: 11.0%
Identity: 55%
PDB header:membrane protein, viral protein
Chain: A: PDB Molecule:protease ns2-3;
PDBTitle: solution nmr structure of hcv ns2 protein, membrane segment2 (1-27)

Phyre2
1
d2ok5a4
2
d1k3ra2
3
c1k3rA_
4
d1b93a_
5
d1vmda_
6
c2fwtA_
7
c4a8xB_
8
c3eopB_
9
d2gbsa1
10
d1zcea1
11
d2g2xa1
12
d2ar1a1
13
d2evea1
14
d2dkya1
15
c3u99A_
16
d1y5ia1
17
c2k8qA_
18
c3eudE_
19
d1w4ma_
20
c2jy0A_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2ok5a4
77.9 46 Fold:Complement control module/SCR domain
Superfamily:Complement control module/SCR domain
Family:Complement control module/SCR domain
2d1k3ra2
74.8 42 Fold:alpha/beta knot
Superfamily:alpha/beta knot
Family:Hypothetical protein MTH1 (MT0001), dimerisation domain
3c1k3rA_
58.6 44 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved protein mt0001;
PDBTitle: crystal structure of the methyltransferase with a knot from2 methanobacterium thermoautotrophicum
4d1b93a_
56.5 18 Fold:Methylglyoxal synthase-like
Superfamily:Methylglyoxal synthase-like
Family:Methylglyoxal synthase, MgsA
5d1vmda_
26.6 13 Fold:Methylglyoxal synthase-like
Superfamily:Methylglyoxal synthase-like
Family:Methylglyoxal synthase, MgsA
6c2fwtA_
23.9 21 PDB header:electron transport
Chain: A: PDB Molecule:dhc, diheme cytochrome c;
PDBTitle: crystal structure of dhc purified from rhodobacter2 sphaeroides
7c4a8xB_
23.2 30 PDB header:transcription
Chain: B: PDB Molecule:hook-like, isoform a;
PDBTitle: structure of the core asap complex
8c3eopB_
22.4 50 PDB header:unknown function
Chain: B: PDB Molecule:thymocyte nuclear protein 1;
PDBTitle: crystal structure of the duf55 domain of human thymocyte nuclear2 protein 1
9d2gbsa1
20.4 40 Fold:PUA domain-like
Superfamily:PUA domain-like
Family:Atu2648/PH1033-like
10d1zcea1
19.0 40 Fold:PUA domain-like
Superfamily:PUA domain-like
Family:Atu2648/PH1033-like
11d2g2xa1
18.8 40 Fold:PUA domain-like
Superfamily:PUA domain-like
Family:Atu2648/PH1033-like
12d2ar1a1
18.2 30 Fold:PUA domain-like
Superfamily:PUA domain-like
Family:Atu2648/PH1033-like
13d2evea1
17.4 40 Fold:PUA domain-like
Superfamily:PUA domain-like
Family:Atu2648/PH1033-like
14d2dkya1
16.6 33 Fold:SAM domain-like
Superfamily:SAM/Pointed domain
Family:Variant SAM domain
15c3u99A_
15.9 18 PDB header:electron transport
Chain: A: PDB Molecule:diheme cytochrome c;
PDBTitle: the experimental x-ray structure of the new diheme cytochrome type c2 from shewanella baltica os155 sb-dhc
16d1y5ia1
14.4 40 Fold:Double psi beta-barrel
Superfamily:ADC-like
Family:Formate dehydrogenase/DMSO reductase, C-terminal domain
17c2k8qA_
12.4 29 PDB header:structural protein
Chain: A: PDB Molecule:protein shq1;
PDBTitle: nmr structure of shq1p n-terminal domain
18c3eudE_
12.2 28 PDB header:nuclear protein
Chain: E: PDB Molecule:protein shq1;
PDBTitle: structure of the cs domain of the essential h/aca rnp2 assembly protein shq1p
19d1w4ma_
11.4 19 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:DEP domain
20c2jy0A_
11.0 55 PDB header:membrane protein, viral protein
Chain: A: PDB Molecule:protease ns2-3;
PDBTitle: solution nmr structure of hcv ns2 protein, membrane segment2 (1-27)
21c1qcrD_
not modelled 10.9 19 PDB header:oxidoreductase
Chain: D: PDB Molecule:ubiquinol cytochrome c oxidoreductase;
PDBTitle: crystal structure of bovine mitochondrial cytochrome bc12 complex, alpha carbon atoms only
22d2h80a1
not modelled 10.8 32 Fold:SAM domain-like
Superfamily:SAM/Pointed domain
Family:Variant SAM domain
23d2r5fa1
not modelled 9.8 16 Fold:NagB/RpiA/CoA transferase-like
Superfamily:NagB/RpiA/CoA transferase-like
Family:SorC sugar-binding domain-like
24c2i6sA_
not modelled 9.5 21 PDB header:hydrolase
Chain: A: PDB Molecule:complement c2a fragment;
PDBTitle: complement component c2a
25c3h5jA_
not modelled 9.3 50 PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: leud_1-168 small subunit of isopropylmalate isomerase (rv2987c) from2 mycobacterium tuberculosis
26c3q3wB_
not modelled 8.8 33 PDB header:transferase
Chain: B: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: isopropylmalate isomerase small subunit from campylobacter jejuni.
27c2hcuA_
not modelled 8.8 50 PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: crystal structure of smu.1381 (or leud) from streptococcus2 mutans
28d1uhwa_
not modelled 8.8 22 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:DEP domain
29c2ct6A_
not modelled 8.8 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain-binding glutamic acid-rich-like
PDBTitle: solution structure of the sh3 domain-binding glutamic acid-2 rich-like protein 2
30c3a0bL_
not modelled 8.4 50 PDB header:electron transport
Chain: L: PDB Molecule:photosystem ii reaction center protein l;
PDBTitle: crystal structure of br-substituted photosystem ii complex
31d1v3fa_
not modelled 8.3 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:DEP domain
32d1t0ia_
not modelled 8.2 26 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:NADPH-dependent FMN reductase
33d1sxra_
not modelled 8.0 15 Fold:N-acetylmuramoyl-L-alanine amidase-like
Superfamily:N-acetylmuramoyl-L-alanine amidase-like
Family:N-acetylmuramoyl-L-alanine amidase-like
34c3a0hl_
not modelled 7.8 50 PDB header:electron transport
Chain: L: PDB Molecule:photosystem ii reaction center protein l;
PDBTitle: crystal structure of i-substituted photosystem ii complex
35c3a0hL_
not modelled 7.8 50 PDB header:electron transport
Chain: L: PDB Molecule:photosystem ii reaction center protein l;
PDBTitle: crystal structure of i-substituted photosystem ii complex
36c3a0bl_
not modelled 7.8 50 PDB header:electron transport
Chain: L: PDB Molecule:photosystem ii reaction center protein l;
PDBTitle: crystal structure of br-substituted photosystem ii complex
37d2cu8a2
not modelled 7.7 27 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
38c3t7hB_
not modelled 7.6 13 PDB header:ligase
Chain: B: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7;
PDBTitle: atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and2 mechanism in the autophagy pathway
39d1wo8a1
not modelled 7.3 14 Fold:Methylglyoxal synthase-like
Superfamily:Methylglyoxal synthase-like
Family:Methylglyoxal synthase, MgsA
40c3ju3A_
not modelled 7.2 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 2-oxoacid ferredoxin oxidoreductase, alpha chain;
PDBTitle: crystal structure of alpha chain of probable 2-oxoacid ferredoxin2 oxidoreductase from thermoplasma acidophilum
41c3mbfA_
not modelled 7.1 16 PDB header:lyase
Chain: A: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: crystal structure of fructose bisphosphate aldolase from2 encephalitozoon cuniculi, bound to fructose 1,6-bisphosphate
42d1gl0i_
not modelled 6.4 60 Fold:PMP inhibitors
Superfamily:PMP inhibitors
Family:PMP inhibitors
43d1xmeb2
not modelled 6.4 33 Fold:Transmembrane helix hairpin
Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region
Family:Cytochrome c oxidase subunit II-like, transmembrane region
44d1ixsa_
not modelled 6.2 58 Fold:RuvA C-terminal domain-like
Superfamily:DNA helicase RuvA subunit, C-terminal domain
Family:DNA helicase RuvA subunit, C-terminal domain
45d2iv2x1
not modelled 6.1 20 Fold:Double psi beta-barrel
Superfamily:ADC-like
Family:Formate dehydrogenase/DMSO reductase, C-terminal domain
46d1vfsa1
not modelled 5.9 21 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like
Superfamily:Alanine racemase C-terminal domain-like
Family:Alanine racemase
47c1rpqW_
not modelled 5.9 43 PDB header:membrane protein
Chain: W: PDB Molecule:peptide e131;
PDBTitle: high affinity ige receptor (alpha chain) complexed with tight-binding2 e131 'zeta' peptide from phage display
48c1kcoA_
not modelled 5.9 43 PDB header:protein binding
Chain: A: PDB Molecule:e131 zeta peptide;
PDBTitle: structure of e131 zeta peptide, a potent antagonist of the2 high-affinity ige receptor
49c1rpqZ_
not modelled 5.9 43 PDB header:membrane protein
Chain: Z: PDB Molecule:peptide e131;
PDBTitle: high affinity ige receptor (alpha chain) complexed with tight-binding2 e131 'zeta' peptide from phage display
50c1rpqX_
not modelled 5.9 43 PDB header:membrane protein
Chain: X: PDB Molecule:peptide e131;
PDBTitle: high affinity ige receptor (alpha chain) complexed with tight-binding2 e131 'zeta' peptide from phage display
51d1g1xc_
not modelled 5.6 50 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Ribosomal protein S18
Family:Ribosomal protein S18
52c3kl4B_
not modelled 5.6 60 PDB header:hydrolase
Chain: B: PDB Molecule:signal peptide of yeast dipeptidyl aminopeptidase b;
PDBTitle: recognition of a signal peptide by the signal recognition particle
53d1ea0a1
not modelled 5.5 27 Fold:Single-stranded right-handed beta-helix
Superfamily:Alpha subunit of glutamate synthase, C-terminal domain
Family:Alpha subunit of glutamate synthase, C-terminal domain
54c1rpqY_
not modelled 5.2 43 PDB header:membrane protein
Chain: Y: PDB Molecule:peptide e131;
PDBTitle: high affinity ige receptor (alpha chain) complexed with tight-binding2 e131 'zeta' peptide from phage display

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite