Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA2A559
DateWed Jul 10 14:28:33 BST 2013
Unique Job IDfbeaf2f952f8c7db
SequenceMAKRTAPLLL ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:17.083 Y:13.494 Z:55.964
Model (left) based on template c2voyG_
Top template information
PDB header:hydrolase
Chain: G: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus
Confidence and coverage
Confidence: 55.3% Coverage: 11%
34 residues ( 11% of your sequence) have been modelled with 55.3% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MAKRTAPLLLLTLAVGLAGGSQGDREPVYRDCVLRCEERNCSGDALKHFRSRQPIYMSLA
Secondary structure 
SS confidence 
Disorder  ?????
??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  GWTCRDDCKYECMWFTVGLYLQEGHRVPQFHGKWPFSRFLFIQEPASAVASLLNGLASLV
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  MLCRYRASVPASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSV
Secondary structure 
SS confidence 
Disorder 
???
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  YLCCVRTVGLQHPSVASAFGALLLLLLTGHISYLSLVHFDYGYNMMANVAIGLVNLAWWL
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  VWCLRNRQRLPHTRRCMVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFR
Secondary structure 
SS confidence 
Disorder 
???????
Disorder confidence 
 
   .........310.........320
Sequence  FLEDDSLYLLKESGAMFKLD
Secondary structure 
SS confidence 
Disorder 
?????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 9%)
Alpha helix ( 74%)
Beta strand ( 0%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2voy chain G

3D model

Region: 159 - 192
Aligned: 34
Modelled: 34
Confidence: 55.3%
Identity: 24%
PDB header:hydrolase
Chain: G: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus

Phyre2

PDB 1dx5 chain I domain 1

3D model

Region: 67 - 73
Aligned: 7
Modelled: 7
Confidence: 29.5%
Identity: 43%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: EGF/Laminin
Family: EGF-type module

Phyre2

PDB 2l2r chain A

3D model

Region: 24 - 44
Aligned: 21
Modelled: 21
Confidence: 21.7%
Identity: 33%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:antimicrobial peptide ecamp1;
PDBTitle: helical hairpin structure of a novel antimicrobial peptide ecamp1 from2 seeds of barnyard grass (echinochloa crus-galli)

Phyre2

PDB 1nyr chain A domain 1

3D model

Region: 89 - 97
Aligned: 9
Modelled: 9
Confidence: 21.2%
Identity: 22%
Fold: Anticodon-binding domain-like
Superfamily: Class II aaRS ABD-related
Family: Anticodon-binding domain of Class II aaRS

Phyre2

PDB 1ulk chain A domain 1

3D model

Region: 64 - 70
Aligned: 7
Modelled: 7
Confidence: 18.8%
Identity: 43%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: Plant lectins/antimicrobial peptides
Family: Hevein-like agglutinin (lectin) domain

Phyre2

PDB 1ulk chain A domain 2

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 16.7%
Identity: 40%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: Plant lectins/antimicrobial peptides
Family: Hevein-like agglutinin (lectin) domain

Phyre2

PDB 1m4u chain A

3D model

Region: 36 - 74
Aligned: 39
Modelled: 39
Confidence: 14.9%
Identity: 18%
Fold: Cystine-knot cytokines
Superfamily: Cystine-knot cytokines
Family: Noggin

Phyre2

PDB 1uha chain A domain 1

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 12.9%
Identity: 40%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: Plant lectins/antimicrobial peptides
Family: Hevein-like agglutinin (lectin) domain

Phyre2

PDB 2qrx chain A

3D model

Region: 83 - 109
Aligned: 23
Modelled: 27
Confidence: 12.4%
Identity: 17%
PDB header:dna binding protein
Chain: A: PDB Molecule:gm27569p;
PDBTitle: crystal structure of drosophila melanogaster translin2 protein

Phyre2

PDB 1z1z chain A domain 1

3D model

Region: 74 - 96
Aligned: 23
Modelled: 23
Confidence: 11.3%
Identity: 9%
Fold: Phage tail protein-like
Superfamily: Phage tail protein-like
Family: Lambda phage gpU-like

Phyre2

PDB 1rqr chain A

3D model

Region: 153 - 161
Aligned: 9
Modelled: 8
Confidence: 10.5%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:5'-fluoro-5'-deoxyadenosine synthase;
PDBTitle: crystal structure and mechanism of a bacterial fluorinating enzyme,2 product complex

Phyre2

PDB 1wu8 chain B

3D model

Region: 153 - 161
Aligned: 9
Modelled: 9
Confidence: 10.4%
Identity: 56%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein ph0463;
PDBTitle: crystal structure of project ph0463 from pyrococcus horikoshii ot3

Phyre2

PDB 2zbv chain C

3D model

Region: 153 - 161
Aligned: 9
Modelled: 9
Confidence: 10.4%
Identity: 56%
PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized conserved protein;
PDBTitle: crystal structure of uncharacterized conserved protein from thermotoga2 maritima

Phyre2

PDB 1rqp chain A domain 2

3D model

Region: 153 - 161
Aligned: 9
Modelled: 9
Confidence: 10.1%
Identity: 22%
Fold: Bacterial fluorinating enzyme, N-terminal domain
Superfamily: Bacterial fluorinating enzyme, N-terminal domain
Family: Bacterial fluorinating enzyme, N-terminal domain

Phyre2

PDB 2q6o chain B

3D model

Region: 153 - 161
Aligned: 9
Modelled: 9
Confidence: 10.1%
Identity: 11%
PDB header:biosynthetic protein
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: sall-y70t with sam and cl

Phyre2

PDB 3pja chain K

3D model

Region: 83 - 109
Aligned: 23
Modelled: 27
Confidence: 9.2%
Identity: 35%
PDB header:hydrolase
Chain: K: PDB Molecule:translin-associated protein x;
PDBTitle: crystal structure of human c3po complex

Phyre2

PDB 3cjh chain K

3D model

Region: 18 - 39
Aligned: 20
Modelled: 22
Confidence: 8.8%
Identity: 15%
PDB header:protein transport
Chain: K: PDB Molecule:mitochondrial import inner membrane translocase subunit
PDBTitle: tim8-tim13 complex

Phyre2

PDB 4dg7 chain D

3D model

Region: 83 - 109
Aligned: 23
Modelled: 27
Confidence: 8.8%
Identity: 17%
PDB header:dna binding protein
Chain: D: PDB Molecule:gm27569p;
PDBTitle: low resolution structure of drosophila translin

Phyre2

PDB 3nct chain C

3D model

Region: 17 - 27
Aligned: 11
Modelled: 11
Confidence: 8.6%
Identity: 45%
PDB header:dna binding protein, chaperone
Chain: C: PDB Molecule:protein psib;
PDBTitle: x-ray crystal structure of the bacterial conjugation factor psib, a2 negative regulator of reca

Phyre2

PDB 2wew chain A

3D model

Region: 89 - 97
Aligned: 9
Modelled: 9
Confidence: 8.5%
Identity: 33%
PDB header:lipid transport
Chain: A: PDB Molecule:apolipoprotein m;
PDBTitle: crystal structure of human apom in complex with myristic2 acid

Phyre2
1
c2voyG_
2
d1dx5i1
3
c2l2rA_
4
d1nyra1
5
d1ulka1
6
d1ulka2
7
d1m4ua_
8
d1uhaa1
9
c2qrxA_
10
d1z1za1
11
c1rqrA_
12
c1wu8B_
13
c2zbvC_
14
d1rqpa2
15
c2q6oB_
16
c3pjaK_
17
c3cjhK_
18
c4dg7D_
19
c3nctC_
20
c2wewA_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2voyG_
55.3 24 PDB header:hydrolase
Chain: G: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus
2d1dx5i1
29.5 43 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:EGF/Laminin
Family:EGF-type module
3c2l2rA_
21.7 33 PDB header:antimicrobial protein
Chain: A: PDB Molecule:antimicrobial peptide ecamp1;
PDBTitle: helical hairpin structure of a novel antimicrobial peptide ecamp1 from2 seeds of barnyard grass (echinochloa crus-galli)
4d1nyra1
21.2 22 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
5d1ulka1
18.8 43 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Plant lectins/antimicrobial peptides
Family:Hevein-like agglutinin (lectin) domain
6d1ulka2
16.7 40 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Plant lectins/antimicrobial peptides
Family:Hevein-like agglutinin (lectin) domain
7d1m4ua_
14.9 18 Fold:Cystine-knot cytokines
Superfamily:Cystine-knot cytokines
Family:Noggin
8d1uhaa1
12.9 40 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Plant lectins/antimicrobial peptides
Family:Hevein-like agglutinin (lectin) domain
9c2qrxA_
12.4 17 PDB header:dna binding protein
Chain: A: PDB Molecule:gm27569p;
PDBTitle: crystal structure of drosophila melanogaster translin2 protein
10d1z1za1
11.3 9 Fold:Phage tail protein-like
Superfamily:Phage tail protein-like
Family:Lambda phage gpU-like
11c1rqrA_
10.5 22 PDB header:transferase
Chain: A: PDB Molecule:5'-fluoro-5'-deoxyadenosine synthase;
PDBTitle: crystal structure and mechanism of a bacterial fluorinating enzyme,2 product complex
12c1wu8B_
10.4 56 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein ph0463;
PDBTitle: crystal structure of project ph0463 from pyrococcus horikoshii ot3
13c2zbvC_
10.4 56 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized conserved protein;
PDBTitle: crystal structure of uncharacterized conserved protein from thermotoga2 maritima
14d1rqpa2
10.1 22 Fold:Bacterial fluorinating enzyme, N-terminal domain
Superfamily:Bacterial fluorinating enzyme, N-terminal domain
Family:Bacterial fluorinating enzyme, N-terminal domain
15c2q6oB_
10.1 11 PDB header:biosynthetic protein
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: sall-y70t with sam and cl
16c3pjaK_
9.2 35 PDB header:hydrolase
Chain: K: PDB Molecule:translin-associated protein x;
PDBTitle: crystal structure of human c3po complex
17c3cjhK_
8.8 15 PDB header:protein transport
Chain: K: PDB Molecule:mitochondrial import inner membrane translocase subunit
PDBTitle: tim8-tim13 complex
18c4dg7D_
8.8 17 PDB header:dna binding protein
Chain: D: PDB Molecule:gm27569p;
PDBTitle: low resolution structure of drosophila translin
19c3nctC_
8.6 45 PDB header:dna binding protein, chaperone
Chain: C: PDB Molecule:protein psib;
PDBTitle: x-ray crystal structure of the bacterial conjugation factor psib, a2 negative regulator of reca
20c2wewA_
8.5 33 PDB header:lipid transport
Chain: A: PDB Molecule:apolipoprotein m;
PDBTitle: crystal structure of human apom in complex with myristic2 acid
21d2axtz1
not modelled 8.2 17 Fold:Transmembrane helix hairpin
Superfamily:PsbZ-like
Family:PsbZ-like
22d1wila_
not modelled 8.2 44 Fold:FYVE/PHD zinc finger
Superfamily:FYVE/PHD zinc finger
Family:variant PHD-like domain
23d1myla_
not modelled 8.0 50 Fold:Ribbon-helix-helix
Superfamily:Ribbon-helix-helix
Family:Arc/Mnt-like phage repressors
24d1x5wa1
not modelled 7.2 43 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
25c4j4vD_
not modelled 7.1 25 PDB header:viral protein
Chain: D: PDB Molecule:nucleocapsid protein;
PDBTitle: pentameric sftsvn with su
26d1xb4a1
not modelled 7.1 44 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Vacuolar sorting protein domain
27c2l4uA_
not modelled 7.0 40 PDB header:signaling protein
Chain: A: PDB Molecule:24mer peptide from protein ste5;
PDBTitle: solution structure of ste5pm24 in the presence of sds micelle
28d1en2a2
not modelled 6.9 50 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Plant lectins/antimicrobial peptides
Family:Hevein-like agglutinin (lectin) domain
29c4k7cA_
not modelled 6.8 12 PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase c;
PDBTitle: crystal structure of pepw from lactobacillus rhamnosis hn001 (dr20)2 determined as the selenomet derivative
30c2kgnA_
not modelled 6.7 38 PDB header:signaling protein
Chain: A: PDB Molecule:protein ste5;
PDBTitle: solution structure of ste5pm24 in the zwitterionic dpc2 micelle
31c2kgmA_
not modelled 6.5 38 PDB header:signaling protein
Chain: A: PDB Molecule:protein ste5;
PDBTitle: solution structure of ste5pm24 in sds micelle
32d1bdta_
not modelled 6.5 50 Fold:Ribbon-helix-helix
Superfamily:Ribbon-helix-helix
Family:Arc/Mnt-like phage repressors
33d1b28a_
not modelled 6.5 50 Fold:Ribbon-helix-helix
Superfamily:Ribbon-helix-helix
Family:Arc/Mnt-like phage repressors
34d1mylb_
not modelled 6.4 56 Fold:Ribbon-helix-helix
Superfamily:Ribbon-helix-helix
Family:Arc/Mnt-like phage repressors
35c1yo4A_
not modelled 6.3 18 PDB header:viral protein
Chain: A: PDB Molecule:hypothetical protein x4;
PDBTitle: solution structure of the sars coronavirus orf 7a coded x42 protein
36c2cw5B_
not modelled 5.9 22 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:bacterial fluorinating enzyme homolog;
PDBTitle: crystal structure of a conserved hypothetical protein from2 thermus thermophilus hb8
37c1mp6A_
not modelled 5.7 33 PDB header:membrane protein
Chain: A: PDB Molecule:matrix protein m2;
PDBTitle: structure of the transmembrane region of the m2 protein h+2 channel by solid state nmr spectroscopy
38c2kqtD_
not modelled 5.7 33 PDB header:transport protein
Chain: D: PDB Molecule:m2 protein;
PDBTitle: solid-state nmr structure of the m2 transmembrane peptide of the2 influenza a virus in dmpc lipid bilayers bound to deuterated3 amantadine
39c1nyjD_
not modelled 5.7 33 PDB header:viral protein
Chain: D: PDB Molecule:matrix protein m2;
PDBTitle: the closed state structure of m2 protein h+ channel by2 solid state nmr spectroscopy
40c2kqtA_
not modelled 5.7 33 PDB header:transport protein
Chain: A: PDB Molecule:m2 protein;
PDBTitle: solid-state nmr structure of the m2 transmembrane peptide of the2 influenza a virus in dmpc lipid bilayers bound to deuterated3 amantadine
41c2kqtB_
not modelled 5.7 33 PDB header:transport protein
Chain: B: PDB Molecule:m2 protein;
PDBTitle: solid-state nmr structure of the m2 transmembrane peptide of the2 influenza a virus in dmpc lipid bilayers bound to deuterated3 amantadine
42c1nyjA_
not modelled 5.7 33 PDB header:viral protein
Chain: A: PDB Molecule:matrix protein m2;
PDBTitle: the closed state structure of m2 protein h+ channel by2 solid state nmr spectroscopy
43c1nyjB_
not modelled 5.7 33 PDB header:viral protein
Chain: B: PDB Molecule:matrix protein m2;
PDBTitle: the closed state structure of m2 protein h+ channel by2 solid state nmr spectroscopy
44c1nyjC_
not modelled 5.7 33 PDB header:viral protein
Chain: C: PDB Molecule:matrix protein m2;
PDBTitle: the closed state structure of m2 protein h+ channel by2 solid state nmr spectroscopy
45c2kqtC_
not modelled 5.7 33 PDB header:transport protein
Chain: C: PDB Molecule:m2 protein;
PDBTitle: solid-state nmr structure of the m2 transmembrane peptide of the2 influenza a virus in dmpc lipid bilayers bound to deuterated3 amantadine
46d1m2vb2
not modelled 5.6 30 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily:beta-sandwich domain of Sec23/24
Family:beta-sandwich domain of Sec23/24
47c3axjB_
not modelled 5.5 30 PDB header:dna binding protein
Chain: B: PDB Molecule:translin associated factor x, isoform b;
PDBTitle: high resolution crystal structure of c3po
48c2plxB_
not modelled 5.4 44 PDB header:hydrolase
Chain: B: PDB Molecule:peptide inhibitor;
PDBTitle: trypsin complexed to a synthetic peptide from veronica hederifolia
49d1crba_
not modelled 5.4 22 Fold:Lipocalins
Superfamily:Lipocalins
Family:Fatty acid binding protein-like
50d1j1ja_
not modelled 5.4 26 Fold:alpha-alpha superhelix
Superfamily:Translin
Family:Translin
51d1v54b2
not modelled 5.4 17 Fold:Transmembrane helix hairpin
Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region
Family:Cytochrome c oxidase subunit II-like, transmembrane region
52c3c9jD_
not modelled 5.3 25 PDB header:membrane protein
Chain: D: PDB Molecule:proton channel protein m2, transmembrane segment;
PDBTitle: the crystal structure of transmembrane domain of m2 protein and2 amantadine complex
53d2q49a2
not modelled 5.3 15 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:GAPDH-like
54d1djta_
not modelled 5.3 44 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Scorpion toxin-like
Family:Long-chain scorpion toxins
55c2rnnA_
not modelled 5.2 15 PDB header:ligase
Chain: A: PDB Molecule:e3 sumo-protein ligase siz1;
PDBTitle: solution structure of the n-terminal sap domain of sumo e3 ligases2 from saccharomyces cerevisiae
56d1ahoa_
not modelled 5.2 33 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Scorpion toxin-like
Family:Long-chain scorpion toxins
57c2i5oA_
not modelled 5.2 50 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase eta;
PDBTitle: solution structure of the ubiquitin-binding zinc finger2 (ubz) domain of the human dna y-polymerase eta

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite