Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA1E960
DateWed Jul 10 14:29:05 BST 2013
Unique Job IDafb3a6805f36e8c7
SequenceMKIIILLGLI ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:18.943 Y:19.230 Z:29.765
Model (left) based on template d1y7ta1
Top template information
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
Confidence and coverage
Confidence: 16.1% Coverage: 12%
34 residues ( 12% of your sequence) have been modelled with 16.1% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKIIILLGLIGASSSAPLISQRLLSASNSHELLLNLNNGQLLPLQFQGAFNSWIPPFPGF
Secondary structure 


















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Disorder  ??



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?
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   .........70.........80.........90.........100.........110.........120
Sequence  LQQQQAQVSGRPQFTLSTLESFAGLFPNQIPLSRQVGLAQGGQAGQPDLSQQQTPPQTQQ
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Disorder 

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   .........130.........140.........150.........160.........170.........180
Sequence  SASPMSYVVPVKVPQDQTQMFQYYPVYMLLPWEQPQTVTSSPQHTGQQLFEEQIPFYNQF
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Disorder  ?









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   .........190.........200.........210.........220.........230.........240
Sequence  GFAPPQAEPGVPGGQQHLAFDSFVGTAPETPGMPVEGSLLYPQKEPISFKHDNAGVFMPT
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Disorder 



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   .........250.........260.........270...
Sequence  TSPKPSTDNFFTSGIDPTIAPEQKVKTDSLREP
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Disorder  ???


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Confidence Key
High(9)                    Low (0)
?Disordered ( 44%)
Alpha helix ( 31%)
Beta strand ( 16%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1y7t chain A domain 1

3D model

Region: 1 - 34
Aligned: 34
Modelled: 34
Confidence: 16.1%
Identity: 21%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: LDH N-terminal domain-like

Phyre2

PDB 2v6b chain B

3D model

Region: 1 - 34
Aligned: 29
Modelled: 34
Confidence: 11.6%
Identity: 38%
PDB header:oxidoreductase
Chain: B: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: crystal structure of lactate dehydrogenase from deinococcus2 radiodurans (apo form)

Phyre2

PDB 1s1i chain N

3D model

Region: 206 - 236
Aligned: 31
Modelled: 31
Confidence: 9.4%
Identity: 23%
PDB header:ribosome
Chain: N: PDB Molecule:60s ribosomal protein l17-a;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1i,4 contains 60s subunit. the 40s ribosomal subunit is in file5 1s1h.

Phyre2

PDB 1y0n chain A

3D model

Region: 147 - 154
Aligned: 8
Modelled: 8
Confidence: 8.1%
Identity: 38%
Fold: YehU-like
Superfamily: YehU-like
Family: YehU-like

Phyre2

PDB 1b8p chain A domain 1

3D model

Region: 1 - 39
Aligned: 39
Modelled: 39
Confidence: 6.8%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: LDH N-terminal domain-like

Phyre2

PDB 1hyg chain A

3D model

Region: 1 - 34
Aligned: 29
Modelled: 34
Confidence: 6.7%
Identity: 28%
PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate/malate dehydrogenase;
PDBTitle: crystal structure of mj0490 gene product, the family of2 lactate/malate dehydrogenase

Phyre2

PDB 1mv8 chain A domain 2

3D model

Region: 1 - 34
Aligned: 27
Modelled: 34
Confidence: 6.4%
Identity: 44%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2
1

d1y7ta1
2

c2v6bB_
3

c1s1iN_
4

d1y0na_
5

d1b8pa1
6

c1hygA_
7

d1mv8a2



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1y7ta1



16.1 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
2c2v6bB_



11.6 38 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: crystal structure of lactate dehydrogenase from deinococcus2 radiodurans (apo form)
3c1s1iN_



9.4 23 PDB header:ribosome
Chain: N: PDB Molecule:60s ribosomal protein l17-a;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1i,4 contains 60s subunit. the 40s ribosomal subunit is in file5 1s1h.
4d1y0na_



8.1 38 Fold:YehU-like
Superfamily:YehU-like
Family:YehU-like
5d1b8pa1



6.8 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
6c1hygA_



6.7 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate/malate dehydrogenase;
PDBTitle: crystal structure of mj0490 gene product, the family of2 lactate/malate dehydrogenase
7d1mv8a2



6.4 44 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite