Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA0JLX3
DateWed Jul 10 14:37:17 BST 2013
Unique Job IDadc6907121aa734a
SequenceMEKFHAQYEM ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:44.654 Y:56.912 Z:60.567
Model (left) based on template c3pfqA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
Confidence and coverage
Confidence:100.0% Coverage: 58%
252 residues ( 58% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
321 residues ( 74%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MEKFHAQYEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVKRECWFNPVMSEAELLMMTD
Secondary structure 





















SS confidence 



























































Disorder  ??????


































????














Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  HPNIISLLQVIETKKKLYLIMELCEGKSLYQHIQNAGYLQEDEACPLFKQLLSAVNYCHN
Secondary structure 



















SS confidence 



























































Disorder 





































??



















Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  QGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPAQKLNLFCENYPFSTPEVLLSRPYDM
Secondary structure 




































SS confidence 



























































Disorder 





















































???


Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  RKIDVWGLGVVLYFMVTGKILFDAASIEKLRKQIVAGKCSVPCRLSVELQDLIRLLMTDN
Secondary structure 























SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  PELRPTVAEVMVHPWVTEGSGVFPDPCEEQISLKPDPAIVKAMGYIGFRAQEIEDSLRQR
Secondary structure 




























SS confidence 



























































Disorder 




















?



?????



























?
Disorder confidence 



























































 
   .........310.........320.........330.........340.........350.........360
Sequence  KFNETMASYCLLKKQILKECDRPIRAQPMNPSLTPFPSLVDTPTSHLGLRRRETEPTGLS
Secondary structure 











































SS confidence 



























































Disorder 
















???????????????????????????????????????????
Disorder confidence 



























































 
   .........370.........380.........390.........400.........410.........420
Sequence  LSANRQVSVCGKSTSKKRDRSFSWPGVLGRPIHTTPTMDQTHTRTRSVPCIYSNFCTIHP
Secondary structure 



























































SS confidence 



























































Disorder  ????????????????????????????????????????????????????????????
Disorder confidence 



























































 
   .........430...
Sequence  NSIDESTEGHTSA
Secondary structure 












SS confidence 












Disorder  ?????????????
Disorder confidence 












 

Confidence Key
High(9)                    Low (0)
?Disordered ( 32%)
Alpha helix ( 31%)
Beta strand ( 12%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3pfq chain A

3D model

Region: 6 - 258
Aligned: 252
Modelled: 253
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii

Phyre2

PDB 1ym7 chain C

3D model

Region: 6 - 258
Aligned: 252
Modelled: 253
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)

Phyre2

PDB 2acx chain B

3D model

Region: 5 - 258
Aligned: 253
Modelled: 254
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp

Phyre2

PDB 3nyo chain B

3D model

Region: 6 - 258
Aligned: 252
Modelled: 253
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp

Phyre2

PDB 1koa chain A

3D model

Region: 2 - 266
Aligned: 264
Modelled: 265
Confidence: 100.0%
Identity: 26%
PDB header:kinase
Chain: A: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains

Phyre2

PDB 3c4w chain B

3D model

Region: 5 - 258
Aligned: 253
Modelled: 254
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a

Phyre2

PDB 3q5i chain A

3D model

Region: 1 - 266
Aligned: 260
Modelled: 266
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase;
PDBTitle: crystal structure of pbanka_031420

Phyre2

PDB 3c4y chain A

3D model

Region: 5 - 258
Aligned: 253
Modelled: 254
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a

Phyre2

PDB 4im2 chain A

3D model

Region: 5 - 255
Aligned: 233
Modelled: 234
Confidence: 100.0%
Identity: 29%
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1

Phyre2

PDB 3qa8 chain H

3D model

Region: 9 - 256
Aligned: 247
Modelled: 248
Confidence: 100.0%
Identity: 28%
PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 2c30 chain A

3D model

Region: 2 - 259
Aligned: 256
Modelled: 258
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6;
PDBTitle: crystal structure of the human p21-activated kinase 6

Phyre2

PDB 3qa8 chain A

3D model

Region: 9 - 256
Aligned: 247
Modelled: 248
Confidence: 100.0%
Identity: 28%
PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 3soa chain A

3D model

Region: 3 - 257
Aligned: 253
Modelled: 255
Confidence: 100.0%
Identity: 31%
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit
PDBTitle: full-length human camkii

Phyre2

PDB 3tku chain B

3D model

Region: 6 - 258
Aligned: 252
Modelled: 251
Confidence: 100.0%
Identity: 25%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil

Phyre2

PDB 3ckx chain A

3D model

Region: 6 - 256
Aligned: 249
Modelled: 251
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine

Phyre2

PDB 4fij chain A

3D model

Region: 3 - 261
Aligned: 257
Modelled: 259
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: catalytic domain of human pak4

Phyre2

PDB 2j4z chain A domain 1

3D model

Region: 6 - 261
Aligned: 254
Modelled: 256
Confidence: 100.0%
Identity: 29%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 1phk chain A

3D model

Region: 4 - 259
Aligned: 256
Modelled: 256
Confidence: 100.0%
Identity: 28%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 4fie chain B

3D model

Region: 2 - 261
Aligned: 258
Modelled: 260
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: full-length human pak4

Phyre2

PDB 2vwi chain C

3D model

Region: 5 - 256
Aligned: 252
Modelled: 252
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: C: PDB Molecule:serine/threonine-protein kinase osr1;
PDBTitle: structure of the osr1 kinase, a hypertension drug target

Phyre2

PDB 1kob chain A

3D model

Region: 3 - 322
Aligned: 319
Modelled: 319
Confidence: 100.0%
Identity: 23%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
1

c3pfqA_
2

c1ym7C_
3

c2acxB_
4

c3nyoB_
5

c1koaA_
6

c3c4wB_
7

c3q5iA_
8

c3c4yA_
9

c4im2A_
10

c3qa8H_
11

c2c30A_
12

c3qa8A_
13

c3soaA_
14

c3tkuB_
15

c3ckxA_
16

c4fijA_
17

d2j4za1
18

d1phka_
19

c4fieB_
20

c2vwiC_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49

d1koba_
50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139



140



141



142



143



144



145



146



147



148



149



150



151



152



153



154



155



156



157



158



159



160



161



162



163



164



165



166



167



168



169



170



171



172



173



174



175



176



177



178



179



180



181



182



183



184



185



186



187



188



189



190



191



192



193



194



195



196



197



198



199



200



201



202



203



204



205



206



207



208



209



210



211



212



213



214



215



216



217



218



219



220



221



222



223



224



225



226



227



228



229



230



231



232



233



234



235



236



237



238



239



240



241



242



243



244



245



246



247



248



249



250



251



252



253



254



255



256



257



258



259



260



261



262



263



264



265



266



267



268



269



270



271



272



273



274



275



276



277



278



279



280



281



282



283



284



285



286



287



288



289



290



291



292



293



294



295



296



297



298



299



300



301



302



303



304



305



306



307



308



309



310



311



312



313



314



315



316



317



318



319



320



321



322



323



324



325



326



327



328



329



330



331



332



333



334



335



336



337



338



339



340



341



342



343



344



345



346



347



348



349



350



351



352



353



354



355



356



357



358



359



360



361



362



363



364



365



366



367






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3pfqA_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
2c1ym7C_



100.0 25 PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)
3c2acxB_



100.0 26 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp
4c3nyoB_



100.0 27 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp
5c1koaA_



100.0 26 PDB header:kinase
Chain: A: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains
6c3c4wB_



100.0 28 PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a
7c3q5iA_



100.0 32 PDB header:transferase
Chain: A: PDB Molecule:protein kinase;
PDBTitle: crystal structure of pbanka_031420
8c3c4yA_



100.0 28 PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
9c4im2A_



100.0 29 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1
10c3qa8H_



100.0 28 PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
11c2c30A_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6;
PDBTitle: crystal structure of the human p21-activated kinase 6
12c3qa8A_



100.0 28 PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
13c3soaA_



100.0 31 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit
PDBTitle: full-length human camkii
14c3tkuB_



100.0 25 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil
15c3ckxA_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine
16c4fijA_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: catalytic domain of human pak4
17d2j4za1



100.0 29 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
18d1phka_



100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
19c4fieB_



100.0 24 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: full-length human pak4
20c2vwiC_



100.0 27 PDB header:transferase
Chain: C: PDB Molecule:serine/threonine-protein kinase osr1;
PDBTitle: structure of the osr1 kinase, a hypertension drug target
21c2jamB_



not modelled 100.0 33 PDB header:transferase
Chain: B: PDB Molecule:calcium/calmodulin-dependent protein kinase type
PDBTitle: crystal structure of human calmodulin-dependent protein2 kinase i g
22c3lijA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with
PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp
23c2qg5D_



not modelled 100.0 32 PDB header:transferase
Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase;
PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840
24c2fo0A_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
25d1jksa_



not modelled 100.0 31 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
26c2a27B_



not modelled 100.0 31 PDB header:transferase
Chain: B: PDB Molecule:death-associated protein kinase 2;
PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit
27c2bmcD_



not modelled 100.0 29 PDB header:transferase
Chain: D: PDB Molecule:serine threonine-protein kinase 6;
PDBTitle: aurora-2 t287d t288d complexed with pha-680632
28c3d9vA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil
29c2y7jB_



not modelled 100.0 28 PDB header:transferase
Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain,
PDBTitle: structure of human phosphorylase kinase, gamma 2
30d1yhwa1



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
31c3hztA_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase 3;
PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860
32c2wtkC_



not modelled 100.0 27 PDB header:transferase/metal-binding protein
Chain: C: PDB Molecule:serine/threonine-protein kinase 11;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
33c2bdwB_



not modelled 100.0 32 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein k11e8.1d;
PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii
34c1oplA_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
35c3dfaA_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920;
PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum
36c2ya9A_



not modelled 100.0 32 PDB header:transferase
Chain: A: PDB Molecule:death-associated protein kinase 2;
PDBTitle: crystal structure of the autoinhibited form of mouse dapk2
37d1xjda_



not modelled 100.0 30 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
38c1xjdA_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, theta type;
PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution
39d1nvra_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
40d1tkia_



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
41c2j51A_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase;
PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
42d2jfla1



not modelled 100.0 29 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
43c2cgvA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk1;
PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening
44d1o6la_



not modelled 100.0 31 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
45c1kobB_



not modelled 100.0 24 PDB header:kinase
Chain: B: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (aplysia), autoregulated protein2 kinase domain
46c2h6dA_



not modelled 100.0 34 PDB header:signaling protein,transferase
Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit
PDBTitle: protein kinase domain of the human 5'-amp-activated protein2 kinase catalytic subunit alpha-2 (ampk alpha-2 chain)
47d1koaa2



not modelled 100.0 24 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
48c2zv2A_



not modelled 100.0 34 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase kinase 2;
PDBTitle: crystal structure of human calcium/calmodulin-dependent protein kinase2 kinase 2, beta, camkk2 kinase domain in complex with sto-609
49d1koba_



100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
50c2vz6A_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:calcium calmodulin dependent protein kinase type ii alpha
PDBTitle: structure of human calcium calmodulin dependent protein2 kinase type ii alpha (camk2a) in complex with indirubin3 e804
51c2y94A_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit alpha-1;
PDBTitle: structure of an active form of mammalian ampk
52d1xwsa_



not modelled 100.0 34 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
53c3zgwA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:maternal embryonic leucine zipper kinase;
PDBTitle: crystal structure of maternal embryonic leucine zipper2 kinase (melk) in complex with amp-pnp
54c2x4fA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:myosin light chain kinase family member 4;
PDBTitle: the crystal structure of the human myosin light chain2 kinase loc340156.
55c2h8hA_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
56c2wtkB_



not modelled 100.0 23 PDB header:transferase/metal-binding protein
Chain: B: PDB Molecule:ste20-related kinase adapter protein alpha;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
57c2vd5A_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:dmpk protein;
PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii
58c2clqA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5
59c1y57A_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
60c2vrxB_



not modelled 100.0 27 PDB header:cell cycle/transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase 12-a;
PDBTitle: structure of aurora b kinase in complex with zm447439
61c2j2iB_



not modelled 100.0 34 PDB header:transferase
Chain: B: PDB Molecule:proto-oncogene serine/threonine-protein kinase pim-1;
PDBTitle: crystal structure of the humab pim1 in complex with2 ly333531
62c3c0hB_



not modelled 100.0 31 PDB header:transferase
Chain: B: PDB Molecule:peripheral plasma membrane protein cask;
PDBTitle: cask cam-kinase domain- amppnp complex, p1 form
63c2r5tA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase sgk1;
PDBTitle: crystal structure of inactive serum and glucocorticoid-2 regulated kinase 1 in complex with amp-pnp
64c1zrzA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, iota;
PDBTitle: crystal structure of the catalytic domain of atypical2 protein kinase c-iota
65d1fota_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
66c3kl8C_



not modelled 100.0 31 PDB header:transferase/ transferase inhibitor
Chain: C: PDB Molecule:calcium/calmodulin dependent protein kinase ii;
PDBTitle: camkiintide inhibitor complex
67c2r7bA_



not modelled 100.0 26 PDB header:signaling protein, transferase
Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1;
PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
68d1uu3a_



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
69c4fl2A_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
70c3comB_



not modelled 100.0 26 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase 4;
PDBTitle: crystal structure of mst1 kinase
71c2j0kB_



not modelled 100.0 26 PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.
72c3h4jB_



not modelled 100.0 33 PDB header:transferase
Chain: B: PDB Molecule:snf1-like protein kinase ssp2;
PDBTitle: crystal structure of pombe ampk kdaid fragment
73c3vw6B_



not modelled 100.0 25 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
74d1rdqe_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
75c3ku2A_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:calmodulin-domain protein kinase 1;
PDBTitle: crystal structure of inactivated form of cdpk1 from toxoplasma gondii,2 tgme49.101440
76c1k9aB_



not modelled 100.0 28 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
77c1mruB_



not modelled 100.0 29 PDB header:transferase
Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb;
PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb.
78d1qcfa3



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
79c3zzwA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2
80c2i0eB_



not modelled 100.0 27 PDB header:transferase
Chain: B: PDB Molecule:protein kinase c-beta ii;
PDBTitle: structure of catalytic domain of human protein kinase c2 beta ii complexed with a bisindolylmaleimide inhibitor
81d1o6ya_



not modelled 100.0 29 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
82c4eutA_



not modelled 100.0 29 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of bx-795 complexed with unphosphorylated human tbk1 kinase-2 uld domain
83c2cn5A_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk2;
PDBTitle: crystal structure of human chk2 in complex with adp
84c2ozoA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
85c2qhnA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk1;
PDBTitle: crystal structure of chek1 in complex with inhibitor 1a
86d1unla_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
87d1xh6a1



not modelled 100.0 29 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
88c2in6A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:wee1-like protein kinase;
PDBTitle: wee1 kinase complex with inhibitor pd311839
89c2a1aB_



not modelled 100.0 28 PDB header:protein synthesis/transferase
Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein
PDBTitle: pkr kinase domain-eif2alpha complex
90c3igoA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:calmodulin-domain protein kinase 1;
PDBTitle: crystal structure of cryptosporidium parvum cdpk1, cgd3_920
91c4dc2A_



not modelled 100.0 25 PDB header:transferase/transferase substrate
Chain: A: PDB Molecule:protein kinase c iota type;
PDBTitle: structure of pkc in complex with a substrate peptide from par-3
92c3is5E_



not modelled 100.0 35 PDB header:transferase
Chain: E: PDB Molecule:calcium-dependent protein kinase;
PDBTitle: crystal structure of cdpk kinase domain from toxoplasma gondii,2 tgme49_018720
93c2c0iA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
94c3fbvL_



not modelled 100.0 30 PDB header:transferase, hydrolase
Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1
95d1gzka_



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
96d1opja_



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
97c3p23B_



not modelled 100.0 29 PDB header:hydrolase, transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp
98c3an0A_



not modelled 100.0 22 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6;
PDBTitle: crystal structure of non-phosphorylated map2k6 as a putative auto2 inhibition state
99c2x7fA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:traf2 and nck-interacting protein kinase;
PDBTitle: crystal structure of the kinase domain of human traf2- and2 nck-interacting kinase with wee1chk1 inhibitor
100c3i6wB_



not modelled 100.0 32 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase chk2;
PDBTitle: structure and activation mechanism of the chk2 dna-damage checkpoint2 kinase
101c2pziA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng;
PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
102c4dn5A_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 14;
PDBTitle: crystal structure of nf-kb-inducing kinase (nik)
103d3blha1



not modelled 100.0 27 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
104c3dlsA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:pas domain-containing serine/threonine-protein kinase;
PDBTitle: crystal structure of human pas kinase bound to adp
105c3i6uA_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk2;
PDBTitle: structure and activation mechanism of the chk2 dna-damage checkpoint2 kinase
106d1s9ja_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
107d1qpca_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
108c2qr8A_



not modelled 100.0 32 PDB header:transferase
Chain: A: PDB Molecule:ribosomal protein s6 kinase alpha-3;
PDBTitle: 2.0a x-ray structure of c-terminal kinase domain of p90 ribosomal s62 kinase 2 (rsk2)
109d3bu3a1



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
110c3eqiA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 1;
PDBTitle: x-ray structure of the human mitogen-activated protein kinase kinase 12 (mek1) in a binary complex with adp and mg2p
111c1u5qA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine protein kinase tao2;
PDBTitle: crystal structure of the tao2 kinase domain: activation and2 specifity of a ste20p map3k
112c3kvwA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase
PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand
113c2pvfA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of tyrosine phosphorylated activated fgf receptor 22 (fgfr2) kinase domain in complex with atp analog and substrate3 peptide
114c3udbF_



not modelled 100.0 34 PDB header:transferase
Chain: F: PDB Molecule:serine/threonine-protein kinase srk2e;
PDBTitle: crystal structure of snrk2.6
115d1u5ra_



not modelled 100.0 22 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
116c3cblA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
117c2jedA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c theta;
PDBTitle: the crystal structure of the kinase domain of the protein2 kinase c theta in complex with nvp-xaa228 at 2.32a3 resolution.
118c2ivsA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
119d1k2pa_



not modelled 100.0 22 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
120c2zmcA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:dual specificity protein kinase ttk;
PDBTitle: crystal structure of human mitotic checkpoint kinase mps1 catalytic2 domain apo form

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite