Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA0AUV4
DateTue Jul 30 13:10:30 BST 2013
Unique Job ID56c46adebed88290
SequenceMPAHIEEELP ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:43.746 Y:57.652 Z:61.469
Model (left) based on template c3pfqA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
Confidence and coverage
Confidence:100.0% Coverage: 53%
270 residues ( 53% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol
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Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPAHIEEELPPPSPQPSNPEDGELYSQYKVVRTLGHGTYAKVLLAKHWLTGTPVAVKVLL
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Disorder  ?????????????????????????


































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   .........70.........80.........90.........100.........110.........120
Sequence  KNKPCFQPAMKEANIMKKIKHPNIVSLLQVFETKTRGYLIMELVEGQELYEYIKSSGHIE
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Disorder 


??




















































??
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   .........130.........140.........150.........160.........170.........180
Sequence  EDEARQIFLQILSAVSYCHGLGIVHRDLKPDNIMIDDKGSIKIIDFGLSTQVKPGDLLDE
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   .........190.........200.........210.........220.........230.........240
Sequence  HCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPFDSYIIPELQRQILAGVYP
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???










































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   .........250.........260.........270.........280.........290.........300
Sequence  APCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWLRGHCKGLTNIHEEPVPVRPDPDIV
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???
?????????






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   .........310.........320.........330.........340.........350.........360
Sequence  DAMQYIGFQAKDIRESLTKEKFNEMSAAYYLLEEQALQREVRSTQAPTVSQVKAPFPSMD
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?
?













????????????????????????
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   .........370.........380.........390.........400.........410.........420
Sequence  AGEASCLKIKRSGSASILGRSVWPPSIDQEPAYVQKVRQRAGRRSSGHGLLFEANQMTPT
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Disorder  ????????????????????????????????????????????????????????????
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   .........430.........440.........450.........460.........470.........480
Sequence  QDQHHIRAMSVPCMLSTSSISEESVSEKREENLSHIALAEDKPIRSRGWCRGIMRWTRRV
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Disorder  ????????????????????????????????????????????????????????????
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   .........490.........500........
Sequence  GNAIRTLCCCIPSRKTPQLGQSRVSPQK
Secondary structure 



















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Disorder  ???

?
?????????????????????
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Confidence Key
High(9)                    Low (0)
?Disordered ( 42%)
Alpha helix ( 28%)
Beta strand ( 10%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3pfq chain A

3D model

Region: 25 - 295
Aligned: 270
Modelled: 271
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii

Phyre2

PDB 3nyo chain B

3D model

Region: 25 - 297
Aligned: 272
Modelled: 273
Confidence: 100.0%
Identity: 31%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp

Phyre2

PDB 2acx chain B

3D model

Region: 25 - 296
Aligned: 271
Modelled: 272
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp

Phyre2

PDB 1ym7 chain C

3D model

Region: 25 - 296
Aligned: 271
Modelled: 272
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)

Phyre2

PDB 1koa chain A

3D model

Region: 14 - 285
Aligned: 271
Modelled: 272
Confidence: 100.0%
Identity: 29%
PDB header:kinase
Chain: A: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains

Phyre2

PDB 3c4w chain B

3D model

Region: 25 - 297
Aligned: 272
Modelled: 273
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a

Phyre2

PDB 3qa8 chain H

3D model

Region: 29 - 276
Aligned: 247
Modelled: 248
Confidence: 100.0%
Identity: 31%
PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 3c4y chain A

3D model

Region: 26 - 296
Aligned: 270
Modelled: 271
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a

Phyre2

PDB 3q5i chain A

3D model

Region: 21 - 287
Aligned: 261
Modelled: 267
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase;
PDBTitle: crystal structure of pbanka_031420

Phyre2

PDB 4im2 chain A

3D model

Region: 28 - 273
Aligned: 227
Modelled: 230
Confidence: 100.0%
Identity: 28%
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1

Phyre2

PDB 3qa8 chain A

3D model

Region: 29 - 276
Aligned: 247
Modelled: 248
Confidence: 100.0%
Identity: 30%
PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 3soa chain A

3D model

Region: 22 - 276
Aligned: 252
Modelled: 255
Confidence: 100.0%
Identity: 37%
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit
PDBTitle: full-length human camkii

Phyre2

PDB 2fo0 chain A

3D model

Region: 2 - 272
Aligned: 270
Modelled: 271
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 3tku chain B

3D model

Region: 26 - 290
Aligned: 264
Modelled: 263
Confidence: 100.0%
Identity: 26%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil

Phyre2

PDB 3ckx chain A

3D model

Region: 26 - 276
Aligned: 249
Modelled: 251
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine

Phyre2

PDB 2c30 chain A

3D model

Region: 20 - 278
Aligned: 257
Modelled: 259
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6;
PDBTitle: crystal structure of the human p21-activated kinase 6

Phyre2

PDB 2j4z chain A domain 1

3D model

Region: 25 - 277
Aligned: 251
Modelled: 253
Confidence: 100.0%
Identity: 32%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 4fij chain A

3D model

Region: 20 - 278
Aligned: 257
Modelled: 259
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: catalytic domain of human pak4

Phyre2

PDB 1opl chain A

3D model

Region: 2 - 272
Aligned: 270
Modelled: 271
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 2vwi chain C

3D model

Region: 25 - 276
Aligned: 252
Modelled: 251
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: C: PDB Molecule:serine/threonine-protein kinase osr1;
PDBTitle: structure of the osr1 kinase, a hypertension drug target

Phyre2
1

c3pfqA_
2

c3nyoB_
3

c2acxB_
4

c1ym7C_
5

c1koaA_
6

c3c4wB_
7

c3qa8H_
8

c3c4yA_
9

c3q5iA_
10

c4im2A_
11

c3qa8A_
12

c3soaA_
13

c2fo0A_
14

c3tkuB_
15

c3ckxA_
16

c2c30A_
17

d2j4za1
18

c4fijA_
19

c1oplA_
20

c2vwiC_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3pfqA_



100.0 30 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
2c3nyoB_



100.0 31 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp
3c2acxB_



100.0 30 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp
4c1ym7C_



100.0 25 PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)
5c1koaA_



100.0 29 PDB header:kinase
Chain: A: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains
6c3c4wB_



100.0 32 PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a
7c3qa8H_



100.0 31 PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
8c3c4yA_



100.0 32 PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
9c3q5iA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:protein kinase;
PDBTitle: crystal structure of pbanka_031420
10c4im2A_



100.0 28 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1
11c3qa8A_



100.0 30 PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
12c3soaA_



100.0 37 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit
PDBTitle: full-length human camkii
13c2fo0A_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
14c3tkuB_



100.0 26 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil
15c3ckxA_



100.0 22 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine
16c2c30A_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6;
PDBTitle: crystal structure of the human p21-activated kinase 6
17d2j4za1



100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
18c4fijA_



100.0 28 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: catalytic domain of human pak4
19c1oplA_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
20c2vwiC_



100.0 29 PDB header:transferase
Chain: C: PDB Molecule:serine/threonine-protein kinase osr1;
PDBTitle: structure of the osr1 kinase, a hypertension drug target
21c4fieB_



not modelled 100.0 28 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: full-length human pak4
22d1phka_



not modelled 100.0 35 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
23c3lijA_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with
PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp
24c2jamB_



not modelled 100.0 36 PDB header:transferase
Chain: B: PDB Molecule:calcium/calmodulin-dependent protein kinase type
PDBTitle: crystal structure of human calmodulin-dependent protein2 kinase i g
25c2qg5D_



not modelled 100.0 33 PDB header:transferase
Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase;
PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840
26c2a27B_



not modelled 100.0 32 PDB header:transferase
Chain: B: PDB Molecule:death-associated protein kinase 2;
PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit
27d1jksa_



not modelled 100.0 34 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
28c2y7jB_



not modelled 100.0 34 PDB header:transferase
Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain,
PDBTitle: structure of human phosphorylase kinase, gamma 2
29d1yhwa1



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
30c3d9vA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil
31c2wtkC_



not modelled 100.0 27 PDB header:transferase/metal-binding protein
Chain: C: PDB Molecule:serine/threonine-protein kinase 11;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
32c3dfaA_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920;
PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum
33c2bmcD_



not modelled 100.0 32 PDB header:transferase
Chain: D: PDB Molecule:serine threonine-protein kinase 6;
PDBTitle: aurora-2 t287d t288d complexed with pha-680632
34d1xjda_



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
35c1xjdA_



not modelled 100.0 32 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, theta type;
PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution
36c2bdwB_



not modelled 100.0 37 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein k11e8.1d;
PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii
37c2h8hA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
38c2ya9A_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:death-associated protein kinase 2;
PDBTitle: crystal structure of the autoinhibited form of mouse dapk2
39c3hztA_



not modelled 100.0 38 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase 3;
PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860
40c1y57A_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
41d1koaa2



not modelled 100.0 29 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
42d1nvra_



not modelled 100.0 30 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
43c1kobB_



not modelled 100.0 30 PDB header:kinase
Chain: B: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (aplysia), autoregulated protein2 kinase domain
44c2x4fA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:myosin light chain kinase family member 4;
PDBTitle: the crystal structure of the human myosin light chain2 kinase loc340156.
45c2cgvA_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk1;
PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening
46c2j51A_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase;
PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
47c2j0kB_



not modelled 100.0 24 PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.
48d2jfla1



not modelled 100.0 27 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
49d1koba_



not modelled 100.0 30 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
50d1o6la_



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
51c4fl2A_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
52c1k9aB_



not modelled 100.0 28 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
53d1tkia_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
54c2ozoA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
55c2zv2A_



not modelled 100.0 36 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase kinase 2;
PDBTitle: crystal structure of human calcium/calmodulin-dependent protein kinase2 kinase 2, beta, camkk2 kinase domain in complex with sto-609
56c2vd5A_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:dmpk protein;
PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii
57c2c0iA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
58d1qcfa3



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
59c2r5tA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase sgk1;
PDBTitle: crystal structure of inactive serum and glucocorticoid-2 regulated kinase 1 in complex with amp-pnp
60c4eutA_



not modelled 100.0 28 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of bx-795 complexed with unphosphorylated human tbk1 kinase-2 uld domain
61c2wtkB_



not modelled 100.0 23 PDB header:transferase/metal-binding protein
Chain: B: PDB Molecule:ste20-related kinase adapter protein alpha;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
62d1xwsa_



not modelled 100.0 35 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
63c2vz6A_



not modelled 100.0 37 PDB header:transferase
Chain: A: PDB Molecule:calcium calmodulin dependent protein kinase type ii alpha
PDBTitle: structure of human calcium calmodulin dependent protein2 kinase type ii alpha (camk2a) in complex with indirubin3 e804
64c2r7bA_



not modelled 100.0 30 PDB header:signaling protein, transferase
Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1;
PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
65c3zzwA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2
66c2h6dA_



not modelled 100.0 39 PDB header:signaling protein,transferase
Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit
PDBTitle: protein kinase domain of the human 5'-amp-activated protein2 kinase catalytic subunit alpha-2 (ampk alpha-2 chain)
67c2pziA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng;
PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
68c1mruB_



not modelled 100.0 29 PDB header:transferase
Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb;
PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb.
69c1zrzA_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, iota;
PDBTitle: crystal structure of the catalytic domain of atypical2 protein kinase c-iota
70c2clqA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5
71d1uu3a_



not modelled 100.0 30 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
72d1fota_



not modelled 100.0 30 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
73d1opja_



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
74c2j2iB_



not modelled 100.0 35 PDB header:transferase
Chain: B: PDB Molecule:proto-oncogene serine/threonine-protein kinase pim-1;
PDBTitle: crystal structure of the humab pim1 in complex with2 ly333531
75c2y94A_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit alpha-1;
PDBTitle: structure of an active form of mammalian ampk
76c3c0hB_



not modelled 100.0 31 PDB header:transferase
Chain: B: PDB Molecule:peripheral plasma membrane protein cask;
PDBTitle: cask cam-kinase domain- amppnp complex, p1 form
77c3comB_



not modelled 100.0 26 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase 4;
PDBTitle: crystal structure of mst1 kinase
78d1o6ya_



not modelled 100.0 29 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
79c2vrxB_



not modelled 100.0 31 PDB header:cell cycle/transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase 12-a;
PDBTitle: structure of aurora b kinase in complex with zm447439
80c3kl8C_



not modelled 100.0 36 PDB header:transferase/ transferase inhibitor
Chain: C: PDB Molecule:calcium/calmodulin dependent protein kinase ii;
PDBTitle: camkiintide inhibitor complex
81c2a1aB_



not modelled 100.0 27 PDB header:protein synthesis/transferase
Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein
PDBTitle: pkr kinase domain-eif2alpha complex
82c3vw6B_



not modelled 100.0 30 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
83d1qpca_



not modelled 100.0 27 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
84d1rdqe_



not modelled 100.0 34 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
85c3fbvL_



not modelled 100.0 31 PDB header:transferase, hydrolase
Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1
86c3zgwA_



not modelled 100.0 32 PDB header:transferase
Chain: A: PDB Molecule:maternal embryonic leucine zipper kinase;
PDBTitle: crystal structure of maternal embryonic leucine zipper2 kinase (melk) in complex with amp-pnp
87c3ku2A_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:calmodulin-domain protein kinase 1;
PDBTitle: crystal structure of inactivated form of cdpk1 from toxoplasma gondii,2 tgme49.101440
88d1unla_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
89c4dn5A_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 14;
PDBTitle: crystal structure of nf-kb-inducing kinase (nik)
90c2i0eB_



not modelled 100.0 31 PDB header:transferase
Chain: B: PDB Molecule:protein kinase c-beta ii;
PDBTitle: structure of catalytic domain of human protein kinase c2 beta ii complexed with a bisindolylmaleimide inhibitor
91c2qhnA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk1;
PDBTitle: crystal structure of chek1 in complex with inhibitor 1a
92d1xh6a1



not modelled 100.0 34 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
93c2cn5A_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk2;
PDBTitle: crystal structure of human chk2 in complex with adp
94c3p23B_



not modelled 100.0 29 PDB header:hydrolase, transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp
95c2in6A_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:wee1-like protein kinase;
PDBTitle: wee1 kinase complex with inhibitor pd311839
96c3is5E_



not modelled 100.0 33 PDB header:transferase
Chain: E: PDB Molecule:calcium-dependent protein kinase;
PDBTitle: crystal structure of cdpk kinase domain from toxoplasma gondii,2 tgme49_018720
97c3h4jB_



not modelled 100.0 35 PDB header:transferase
Chain: B: PDB Molecule:snf1-like protein kinase ssp2;
PDBTitle: crystal structure of pombe ampk kdaid fragment
98c4dc2A_



not modelled 100.0 32 PDB header:transferase/transferase substrate
Chain: A: PDB Molecule:protein kinase c iota type;
PDBTitle: structure of pkc in complex with a substrate peptide from par-3
99d1gzka_



not modelled 100.0 35 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
100d3bu3a1



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
101c3cblA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
102c3eqiA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 1;
PDBTitle: x-ray structure of the human mitogen-activated protein kinase kinase 12 (mek1) in a binary complex with adp and mg2p
103c2ivsA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
104d1k2pa_



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
105d1lufa_



not modelled 100.0 27 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
106c1lufA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk;
PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation
107c2x7fA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:traf2 and nck-interacting protein kinase;
PDBTitle: crystal structure of the kinase domain of human traf2- and2 nck-interacting kinase with wee1chk1 inhibitor
108c2pvfA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of tyrosine phosphorylated activated fgf receptor 22 (fgfr2) kinase domain in complex with atp analog and substrate3 peptide
109c3p1aA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:membrane-associated tyrosine- and threonine-specific cdc2-
PDBTitle: structure of human membrane-associated tyrosine- and threonine-2 specific cdc2-inhibitory kinase myt1 (pkmyt1)
110c3dpkA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor;
PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor
111c3i6wB_



not modelled 100.0 35 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase chk2;
PDBTitle: structure and activation mechanism of the chk2 dna-damage checkpoint2 kinase
112c2bujA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 16;
PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine
113c3an0A_



not modelled 100.0 27 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6;
PDBTitle: crystal structure of non-phosphorylated map2k6 as a putative auto2 inhibition state
114c3g0eA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:mast/stem cell growth factor receptor;
PDBTitle: kit kinase domain in complex with sunitinib
115c3kvwA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase
PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand
116c3dlsA_



not modelled 100.0 32 PDB header:transferase
Chain: A: PDB Molecule:pas domain-containing serine/threonine-protein kinase;
PDBTitle: crystal structure of human pas kinase bound to adp
117c3lxkA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
118d1s9ja_



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
119c4eqmE_



not modelled 100.0 29 PDB header:transferase
Chain: E: PDB Molecule:protein kinase;
PDBTitle: structural analysis of staphylococcus aureus serine/threonine kinase2 pknb
120d3blha1



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit

Binding site prediction 

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