Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ9NUG6
DateTue Apr 3 15:15:57 BST 2012
Unique Job ID1314d70a36936970

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2zdiC_
Top template information
PDB header:chaperone
Chain: C: PDB Molecule:prefoldin subunit alpha;
PDBTitle: crystal structure of prefoldin from pyrococcus horikoshii2 ot3
Confidence and coverage
Confidence: 97.0% Coverage: 79%
105 residues ( 79% of your sequence) have been modelled with 97.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLSPEAERVLRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVC
Secondary structure 
SS confidence 
Disorder  ?????
?
?
???
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  FGNMFIKMPHPETKEMIEKDQDHLDKEIEKLRKQLKVKVNRLFEAQGKPELKGFNLNPLN
Secondary structure 
SS confidence 
Disorder 
??
????????
Disorder confidence 
 
   .........130...
Sequence  QDELKALKVILKG
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2zdi chain C

3D model

Region: 2 - 106
Aligned: 105
Modelled: 105
Confidence: 97.0%
Identity: 18%
PDB header:chaperone
Chain: C: PDB Molecule:prefoldin subunit alpha;
PDBTitle: crystal structure of prefoldin from pyrococcus horikoshii2 ot3

Phyre2

PDB 1fxk chain C

3D model

Region: 9 - 106
Aligned: 98
Modelled: 98
Confidence: 96.8%
Identity: 15%
Fold: Long alpha-hairpin
Superfamily: Prefoldin
Family: Prefoldin

Phyre2

PDB 2zdi chain A

3D model

Region: 13 - 106
Aligned: 93
Modelled: 94
Confidence: 96.2%
Identity: 12%
PDB header:chaperone
Chain: A: PDB Molecule:prefoldin subunit beta;
PDBTitle: crystal structure of prefoldin from pyrococcus horikoshii2 ot3

Phyre2

PDB 1fxk chain A

3D model

Region: 5 - 106
Aligned: 98
Modelled: 100
Confidence: 89.9%
Identity: 17%
Fold: Long alpha-hairpin
Superfamily: Prefoldin
Family: Prefoldin

Phyre2

PDB 3aei chain A

3D model

Region: 47 - 105
Aligned: 59
Modelled: 59
Confidence: 70.3%
Identity: 24%
PDB header:chaperone
Chain: A: PDB Molecule:prefoldin beta subunit 2;
PDBTitle: crystal structure of the prefoldin beta2 subunit from thermococcus2 strain ks-1

Phyre2

PDB 1go4 chain F

3D model

Region: 21 - 97
Aligned: 73
Modelled: 73
Confidence: 45.7%
Identity: 26%
PDB header:cell cycle
Chain: F: PDB Molecule:mad1 (mitotic arrest deficient)-like 1;
PDBTitle: crystal structure of mad1-mad2 reveals a conserved mad22 binding motif in mad1 and cdc20.

Phyre2

PDB 1k8k chain E

3D model

Region: 39 - 62
Aligned: 24
Modelled: 24
Confidence: 42.5%
Identity: 13%
Fold: Arp2/3 complex 21 kDa subunit ARPC3
Superfamily: Arp2/3 complex 21 kDa subunit ARPC3
Family: Arp2/3 complex 21 kDa subunit ARPC3

Phyre2

PDB 2gbo chain B

3D model

Region: 68 - 95
Aligned: 28
Modelled: 28
Confidence: 27.2%
Identity: 14%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:upf0358 protein ef2458;
PDBTitle: protein of unknown function ef2458 from enterococcus faecalis

Phyre2

PDB 2gbo chain A domain 1

3D model

Region: 68 - 95
Aligned: 28
Modelled: 28
Confidence: 27.2%
Identity: 14%
Fold: Open three-helical up-and-down bundle
Superfamily: EF2458-like
Family: EF2458-like

Phyre2

PDB 2ke4 chain A

3D model

Region: 4 - 110
Aligned: 82
Modelled: 93
Confidence: 24.6%
Identity: 26%
PDB header:membrane protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4

Phyre2

PDB 3dwl chain E

3D model

Region: 55 - 62
Aligned: 8
Modelled: 8
Confidence: 23.2%
Identity: 25%
PDB header:structural protein
Chain: E: PDB Molecule:actin-related protein 2/3 complex subunit 3;
PDBTitle: crystal structure of fission yeast arp2/3 complex lacking the arp22 subunit

Phyre2

PDB 2la3 chain A

3D model

Region: 27 - 65
Aligned: 37
Modelled: 39
Confidence: 21.5%
Identity: 16%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the nmr structure of the protein np_344798.1 reveals a cca-adding2 enzyme head domain

Phyre2

PDB 2kz6 chain A

3D model

Region: 39 - 58
Aligned: 20
Modelled: 20
Confidence: 21.0%
Identity: 35%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of protein cv0426 from chromobacterium violaceum,2 northeast structural genomics consortium (nesg) target cvt2

Phyre2

PDB 3lyv chain F

3D model

Region: 112 - 124
Aligned: 13
Modelled: 13
Confidence: 18.8%
Identity: 31%
PDB header:chaperone
Chain: F: PDB Molecule:ribosome-associated factor y;
PDBTitle: crystal structure of a domain of ribosome-associated factor y from2 streptococcus pyogenes serotype m6. northeast structural genomics3 consortium target id dr64a

Phyre2

PDB 3ka5 chain A

3D model

Region: 112 - 124
Aligned: 13
Modelled: 11
Confidence: 17.6%
Identity: 31%
PDB header:chaperone
Chain: A: PDB Molecule:ribosome-associated protein y (psrp-1);
PDBTitle: crystal structure of ribosome-associated protein y (psrp-1)2 from clostridium acetobutylicum. northeast structural3 genomics consortium target id car123a

Phyre2

PDB 2ivf chain B

3D model

Region: 77 - 121
Aligned: 45
Modelled: 45
Confidence: 16.1%
Identity: 22%
PDB header:oxidoreductase
Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit;
PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum

Phyre2

PDB 3he4 chain A

3D model

Region: 77 - 95
Aligned: 19
Modelled: 19
Confidence: 16.0%
Identity: 37%
PDB header:de novo protein
Chain: A: PDB Molecule:synzip6;
PDBTitle: heterospecific coiled-coil pair synzip5:synzip6

Phyre2

PDB 1t3j chain A

3D model

Region: 62 - 96
Aligned: 35
Modelled: 35
Confidence: 14.2%
Identity: 26%
PDB header:membrane protein
Chain: A: PDB Molecule:mitofusin 1;
PDBTitle: mitofusin domain hr2 v686m/i708m mutant

Phyre2

PDB 1yuz chain B

3D model

Region: 3 - 60
Aligned: 40
Modelled: 42
Confidence: 12.2%
Identity: 13%
PDB header:oxidoreductase
Chain: B: PDB Molecule:nigerythrin;
PDBTitle: partially reduced state of nigerythrin

Phyre2

PDB 2ko2 chain A

3D model

Region: 40 - 93
Aligned: 52
Modelled: 54
Confidence: 11.2%
Identity: 15%
PDB header:membrane protein
Chain: A: PDB Molecule:reticulon-4;
PDBTitle: nogo66

Phyre2
1
c2zdiC_
2
d1fxkc_
3
c2zdiA_
4
d1fxka_
5
c3aeiA_
6
c1go4F_
7
d1k8ke_
8
c2gboB_
9
d2gboa1
10
c2ke4A_
11
c3dwlE_
12
c2la3A_
13
c2kz6A_
14
c3lyvF_
15
c3ka5A_
16
c2ivfB_
17
c3he4A_
18
c1t3jA_
19
c1yuzB_
20
c2ko2A_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2zdiC_
97.0 18 PDB header:chaperone
Chain: C: PDB Molecule:prefoldin subunit alpha;
PDBTitle: crystal structure of prefoldin from pyrococcus horikoshii2 ot3
2d1fxkc_
96.8 15 Fold:Long alpha-hairpin
Superfamily:Prefoldin
Family:Prefoldin
3c2zdiA_
96.2 12 PDB header:chaperone
Chain: A: PDB Molecule:prefoldin subunit beta;
PDBTitle: crystal structure of prefoldin from pyrococcus horikoshii2 ot3
4d1fxka_
89.9 17 Fold:Long alpha-hairpin
Superfamily:Prefoldin
Family:Prefoldin
5c3aeiA_
70.3 24 PDB header:chaperone
Chain: A: PDB Molecule:prefoldin beta subunit 2;
PDBTitle: crystal structure of the prefoldin beta2 subunit from thermococcus2 strain ks-1
6c1go4F_
45.7 26 PDB header:cell cycle
Chain: F: PDB Molecule:mad1 (mitotic arrest deficient)-like 1;
PDBTitle: crystal structure of mad1-mad2 reveals a conserved mad22 binding motif in mad1 and cdc20.
7d1k8ke_
42.5 13 Fold:Arp2/3 complex 21 kDa subunit ARPC3
Superfamily:Arp2/3 complex 21 kDa subunit ARPC3
Family:Arp2/3 complex 21 kDa subunit ARPC3
8c2gboB_
27.2 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:upf0358 protein ef2458;
PDBTitle: protein of unknown function ef2458 from enterococcus faecalis
9d2gboa1
27.2 14 Fold:Open three-helical up-and-down bundle
Superfamily:EF2458-like
Family:EF2458-like
10c2ke4A_
24.6 26 PDB header:membrane protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4
11c3dwlE_
23.2 25 PDB header:structural protein
Chain: E: PDB Molecule:actin-related protein 2/3 complex subunit 3;
PDBTitle: crystal structure of fission yeast arp2/3 complex lacking the arp22 subunit
12c2la3A_
21.5 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the nmr structure of the protein np_344798.1 reveals a cca-adding2 enzyme head domain
13c2kz6A_
21.0 35 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of protein cv0426 from chromobacterium violaceum,2 northeast structural genomics consortium (nesg) target cvt2
14c3lyvF_
18.8 31 PDB header:chaperone
Chain: F: PDB Molecule:ribosome-associated factor y;
PDBTitle: crystal structure of a domain of ribosome-associated factor y from2 streptococcus pyogenes serotype m6. northeast structural genomics3 consortium target id dr64a
15c3ka5A_
17.6 31 PDB header:chaperone
Chain: A: PDB Molecule:ribosome-associated protein y (psrp-1);
PDBTitle: crystal structure of ribosome-associated protein y (psrp-1)2 from clostridium acetobutylicum. northeast structural3 genomics consortium target id car123a
16c2ivfB_
16.1 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit;
PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum
17c3he4A_
16.0 37 PDB header:de novo protein
Chain: A: PDB Molecule:synzip6;
PDBTitle: heterospecific coiled-coil pair synzip5:synzip6
18c1t3jA_
14.2 26 PDB header:membrane protein
Chain: A: PDB Molecule:mitofusin 1;
PDBTitle: mitofusin domain hr2 v686m/i708m mutant
19c1yuzB_
12.2 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:nigerythrin;
PDBTitle: partially reduced state of nigerythrin
20c2ko2A_
11.2 15 PDB header:membrane protein
Chain: A: PDB Molecule:reticulon-4;
PDBTitle: nogo66
21c2y0mB_
not modelled 10.4 30 PDB header:transcription
Chain: B: PDB Molecule:male-specific lethal 1 homolog;
PDBTitle: crystal structure of the complex between dosage2 compensation factors msl1 and mof
22d1oqya1
not modelled 10.1 26 Fold:RuvA C-terminal domain-like
Superfamily:UBA-like
Family:UBA domain
23d1hh8a_
not modelled 9.9 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
24c1y4mC_
not modelled 9.9 30 PDB header:membrane protein
Chain: C: PDB Molecule:herv-frd_6p24.1 provirus ancestral env polyprotein;
PDBTitle: crystal structure of human endogenous retrovirus herv-frd envelope2 protein (syncitin-2)
25c2ykqC_
not modelled 9.8 19 PDB header:rna-binding protein
Chain: C: PDB Molecule:line-1 orf1p;
PDBTitle: structure of the human line-1 orf1p trimer
26c1mofA_
not modelled 9.5 24 PDB header:viral protein
Chain: A: PDB Molecule:moloney murine leukemia virus p15;
PDBTitle: coat protein
27c1lb1C_
not modelled 9.2 13 PDB header:signaling protein
Chain: C: PDB Molecule:guanine nucleotide exchange factor dbs;
PDBTitle: crystal structure of the dbl and pleckstrin homology2 domains of dbs in complex with rhoa
28c3hdeA_
not modelled 9.1 22 PDB header:hydrolase
Chain: A: PDB Molecule:lysozyme;
PDBTitle: crystal structure of full-length endolysin r21 from phage 21
29c2p3xA_
not modelled 8.7 3 PDB header:oxidoreductase
Chain: A: PDB Molecule:polyphenol oxidase, chloroplast;
PDBTitle: crystal structure of grenache (vitis vinifera) polyphenol2 oxidase
30c2l5gB_
not modelled 8.6 21 PDB header:transcription regulator
Chain: B: PDB Molecule:putative uncharacterized protein ncor2;
PDBTitle: co-ordinates and 1h, 13c and 15n chemical shift assignments for the2 complex of gps2 53-90 and smrt 167-207
31d1bt3a_
not modelled 8.6 0 Fold:Di-copper centre-containing domain
Superfamily:Di-copper centre-containing domain
Family:Catechol oxidase
32d1p37a_
not modelled 8.4 20 Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
33d1lpya_
not modelled 8.0 12 Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
34c2q7cC_
not modelled 8.0 28 PDB header:viral protein
Chain: C: PDB Molecule:fusion protein between yeast variant gcn4 and
PDBTitle: crystal structure of iqn17
35c2ka6B_
not modelled 7.8 29 PDB header:transcription regulator
Chain: B: PDB Molecule:signal transducer and activator of transcription
PDBTitle: nmr structure of the cbp-taz2/stat1-tad complex
36d1wpga2
not modelled 7.6 21 Fold:HAD-like
Superfamily:HAD-like
Family:Meta-cation ATPase, catalytic domain P
37d2asra_
not modelled 7.5 21 Fold:Four-helical up-and-down bundle
Superfamily:Aspartate receptor, ligand-binding domain
Family:Aspartate receptor, ligand-binding domain
38d176la_
not modelled 7.4 17 Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
39c2odmA_
not modelled 7.4 19 PDB header:unknown function
Chain: A: PDB Molecule:upf0358 protein mw0995;
PDBTitle: crystal structure of s. aureus ylan, an essential leucine rich protein2 involved in the control of cell shape
40c2y9xC_
not modelled 7.1 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:polyphenol oxidase;
PDBTitle: crystal structure of ppo3, a tyrosinase from agaricus bisporus, in2 deoxy-form that contains additional unknown lectin-like subunit,3 with inhibitor tropolone
41c3kyzA_
not modelled 7.1 30 PDB header:transferase
Chain: A: PDB Molecule:sensor protein pfes;
PDBTitle: the crystal structure of the sensor domain of two-component2 sensor pfes from pseudomonas aeruginosa pa01
42d1zl8a1
not modelled 6.9 19 Fold:L27 domain
Superfamily:L27 domain
Family:L27 domain
43c3uuxD_
not modelled 6.9 15 PDB header:apoptosis
Chain: D: PDB Molecule:mitochondrial division protein 1;
PDBTitle: crystal structure of yeast fis1 in complex with mdv1 fragment2 containing n-terminal extension and coiled coil domains
44d1hqz1_
not modelled 6.8 10 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
45d1udma_
not modelled 6.8 21 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
46c2f9jP_
not modelled 6.7 50 PDB header:rna binding protein
Chain: P: PDB Molecule:splicing factor 3b subunit 1;
PDBTitle: 3.0 angstrom resolution structure of a y22m mutant of the spliceosomal2 protein p14 bound to a region of sf3b155
47d1is1a_
not modelled 6.2 18 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Ribosome recycling factor, RRF
Family:Ribosome recycling factor, RRF
48d1y74a1
not modelled 6.2 19 Fold:L27 domain
Superfamily:L27 domain
Family:L27 domain
49c1u0iA_
not modelled 6.0 47 PDB header:de novo protein
Chain: A: PDB Molecule:iaal-e3;
PDBTitle: iaal-e3/k3 heterodimer
50d1xp8a2
not modelled 5.9 10 Fold:Anti-LPS factor/recA domain
Superfamily:RecA protein, C-terminal domain
Family:RecA protein, C-terminal domain
51c2w9yA_
not modelled 5.8 20 PDB header:lipid transport
Chain: A: PDB Molecule:fatty acid/retinol binding protein protein 7,
PDBTitle: the structure of the lipid binding protein ce-far-7 from2 caenorhabditis elegans
52c1x67A_
not modelled 5.8 13 PDB header:protein binding
Chain: A: PDB Molecule:drebrin-like protein;
PDBTitle: solution structure of the cofilin homology domain of hip-552 (drebrin-like protein)
53c3obhA_
not modelled 5.8 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: x-ray crystal structure of protein sp_0782 (7-79) from streptococcus2 pneumoniae. northeast structural genomics consortium target spr104
54d1ubea2
not modelled 5.5 8 Fold:Anti-LPS factor/recA domain
Superfamily:RecA protein, C-terminal domain
Family:RecA protein, C-terminal domain
55c2wg6L_
not modelled 5.5 21 PDB header:transcription,hydrolase
Chain: L: PDB Molecule:general control protein gcn4,
PDBTitle: proteasome-activating nucleotidase (pan) n-domain (57-134)2 from archaeoglobus fulgidus fused to gcn4, p61a mutant
56d2otaa1
not modelled 5.5 26 Fold:YejL-like
Superfamily:YejL-like
Family:YejL-like
57d1mo6a2
not modelled 5.4 10 Fold:Anti-LPS factor/recA domain
Superfamily:RecA protein, C-terminal domain
Family:RecA protein, C-terminal domain
58c1a3wB_
not modelled 5.4 24 PDB header:transferase
Chain: B: PDB Molecule:pyruvate kinase;
PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+
59c2rdcA_
not modelled 5.4 25 PDB header:lipid binding protein
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a putative lipid binding protein (gsu0061) from2 geobacter sulfurreducens pca at 1.80 a resolution
60c3t07D_
not modelled 5.3 22 PDB header:transferase/transferase inhibitor
Chain: D: PDB Molecule:pyruvate kinase;
PDBTitle: crystal structure of s. aureus pyruvate kinase in complex with a2 naturally occurring bis-indole alkaloid
61d1wiva_
not modelled 5.3 16 Fold:RuvA C-terminal domain-like
Superfamily:UBA-like
Family:UBA domain
62c1gk4A_
not modelled 5.2 14 PDB header:vimentin
Chain: A: PDB Molecule:vimentin;
PDBTitle: human vimentin coil 2b fragment (cys2)

Binding site prediction 

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If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite