Phyre 2 Results for Q5BN46

Email	l.a.kelley@imperial.ac.uk
Description	Q5BN46
Date	Thu Apr 26 09:38:59 BST 2012
Unique Job ID	c1094156034a8ea2

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template d1v0da_

Top template information

Fold:His-Me finger endonucleases
Superfamily:His-Me finger endonucleases
Family:Caspase-activated DNase, CAD (DffB, DFF40)

Confidence and coverage

Confidence:

10.5%

Coverage:

10%

13 residues ( 10% of your sequence) have been modelled with 10.5% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

Please note: You must be registered and logged in to use Phyrealarm.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M A E E C P R A C A E P V A P K A T A P P E R T S D Y Y R V S A D L P G R F N N P G W F R G Y R T Q K A V S V Y R T S N

Secondary structure

SS confidence

Disorder ? ? ? ? ? ?
?
? ? ? ? ? ? ? ?
? ?
? ?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence Q A Y G S R A P T V H E M P K V F Y P N S N K F S Q Q L A A G G M F R N N T L N V Y L E K S I V T G P D N C I T S C D R

Secondary structure

SS confidence

Disorder ?
?
? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . .

Sequence L N F H P S Y N I N R P S I C D

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1v0d chain A

Region: 37 - 49
Aligned: 13
Modelled: 13
Confidence: 10.5%
Identity: 38%
Fold: His-Me finger endonucleases
Superfamily: His-Me finger endonucleases
Family: Caspase-activated DNase, CAD (DffB, DFF40)

Phyre2

PDB 1v0d chain A

Region: 37 - 49
Aligned: 13
Modelled: 13
Confidence: 10.5%
Identity: 38%
PDB header:hydrolase
Chain: A: PDB Molecule:dna fragmentation factor 40 kda subunit;
PDBTitle: crystal structure of caspase-activated dnase (cad)

Phyre2

PDB 2dt7 chain A

Region: 104 - 121
Aligned: 18
Modelled: 18
Confidence: 8.7%
Identity: 28%
PDB header:rna binding protein
Chain: A: PDB Molecule:splicing factor 3a subunit 3;
PDBTitle: solution structure of the second surp domain of human2 splicing factor sf3a120 in complex with a fragment of3 human splicing factor sf3a60

Phyre2

PDB 4a4y chain A

Region: 92 - 98
Aligned: 7
Modelled: 7
Confidence: 6.5%
Identity: 43%
PDB header:protein binding
Chain: A: PDB Molecule:protein mxig;
PDBTitle: structure of the cytosolic domain of the shigella t3ss2 component mxig

Phyre2

PDB 3dv0 chain I

Region: 99 - 123
Aligned: 25
Modelled: 25
Confidence: 6.2%
Identity: 20%
PDB header:oxidoreductase/transferase
Chain: I: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase
PDBTitle: snapshots of catalysis in the e1 subunit of the pyruvate2 dehydrogenase multi-enzyme complex

Phyre2

PDB 3kz5 chain E

Region: 89 - 108
Aligned: 20
Modelled: 20
Confidence: 5.8%
Identity: 20%
PDB header:dna binding protein
Chain: E: PDB Molecule:protein sopb;
PDBTitle: structure of cdomain

Phyre2

PDB 1gwm chain A

Region: 25 - 65
Aligned: 41
Modelled: 41
Confidence: 5.8%
Identity: 17%
Fold: Galactose-binding domain-like
Superfamily: Galactose-binding domain-like
Family: Family 29 carbohydrate binding module, CBM29

Phyre2

PDB 1w4h chain A domain 1

Region: 99 - 123
Aligned: 25
Modelled: 25
Confidence: 5.7%
Identity: 20%
Fold: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
Superfamily: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
Family: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex

Phyre2

PDB 1wcu chain A

Region: 25 - 65
Aligned: 41
Modelled: 41
Confidence: 5.7%
Identity: 24%
PDB header:carbohydrate binding
Chain: A: PDB Molecule:non-catalytic protein 1;
PDBTitle: cbm29_1, a family 29 carbohydrate binding module from2 piromyces equi

Phyre2

PDB 1bal chain A

Region: 99 - 123
Aligned: 25
Modelled: 25
Confidence: 5.6%
Identity: 20%
Fold: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
Superfamily: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
Family: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	A	E	E	C	P	R	A	C	A	E	P	V	A	P	K	A	T	A	P	P	E	R	T	S	D	Y	Y	R	V	S	A	D	L	P	G	R	F	N	N	P	G	W	F	R	G	Y	R	T	Q	K	A	V	S	V	Y	R	T	S	N
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?				?		?	?	?	?	?	?	?	?		?	?																							?	?			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	Q	A	Y	G	S	R	A	P	T	V	H	E	M	P	K	V	F	Y	P	N	S	N	K	F	S	Q	Q	L	A	A	G	G	M	F	R	N	N	T	L	N	V	Y	L	E	K	S	I	V	T	G	P	D	N	C	I	T	S	C	D	R
Secondary structure
SS confidence
Disorder	?		?																?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.
Sequence	L	N	F	H	P	S	Y	N	I	N	R	P	S	I	C	D
Secondary structure
SS confidence
Disorder			?							?	?	?	?	?	?	?
Disorder confidence