Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP39023
DateThu Apr 26 09:26:30 BST 2012
Unique Job IDfe687422d43f91ad

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3iz5C_
Top template information
PDB header:ribosome
Chain: C: PDB Molecule:60s ribosomal protein l3 (l3p);
PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
Confidence and coverage
Confidence:100.0% Coverage: 96%
387 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREV
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Disorder  ??????????????







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   .........70.........80.........90.........100.........110.........120
Sequence  DRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYK
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Disorder 
?????????










































?




?
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   .........130.........140.........150.........160.........170.........180
Sequence  NWHKSKKKAFTKYCKKWQDEDGKKQLEKDFSSMKKYCQVIRVIAHTQMRLLPLRQKKAHL
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Disorder  ??
???????????
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   .........190.........200.........210.........220.........230.........240
Sequence  MEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKL
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Disorder 


?
?
?
?















































??
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   .........250.........260.........270.........280.........290.........300
Sequence  PRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIK
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Disorder  ????????



???







































?????
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   .........310.........320.........330.........340.........350.........360
Sequence  NNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRAL
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Disorder  ??
?
?????????

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????????
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   .........370.........380.........390.........400...
Sequence  EKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA
Secondary structure 

















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Disorder 













??
??????????





??????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3iz5 chain C

3D model

Region: 1 - 393
Aligned: 387
Modelled: 393
Confidence: 100.0%
Identity: 68%
PDB header:ribosome
Chain: C: PDB Molecule:60s ribosomal protein l3 (l3p);
PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome

Phyre2

PDB 4a1a chain B

3D model

Region: 2 - 401
Aligned: 386
Modelled: 386
Confidence: 100.0%
Identity: 63%
PDB header:ribosome
Chain: B: PDB Molecule:ribosomal protein l3;
PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 5s rrna,3 5.8s rrna and proteins of molecule 3.

Phyre2

PDB 3jyw chain C

3D model

Region: 5 - 375
Aligned: 362
Modelled: 371
Confidence: 100.0%
Identity: 67%
PDB header:ribosome
Chain: C: PDB Molecule:60s ribosomal protein l3;
PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution

Phyre2

PDB 2zkr chain B

3D model

Region: 7 - 351
Aligned: 345
Modelled: 345
Confidence: 100.0%
Identity: 98%
PDB header:ribosomal protein/rna
Chain: B: PDB Molecule:rna expansion segment es4;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map

Phyre2

PDB 1s1i chain C

3D model

Region: 8 - 375
Aligned: 359
Modelled: 359
Confidence: 100.0%
Identity: 67%
PDB header:ribosome
Chain: C: PDB Molecule:60s ribosomal protein l3;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1i,4 contains 60s subunit. the 40s ribosomal subunit is in file5 1s1h.

Phyre2

PDB 1vqo chain B domain 1

3D model

Region: 7 - 375
Aligned: 329
Modelled: 333
Confidence: 100.0%
Identity: 37%
Fold: Reductase/isomerase/elongation factor common domain
Superfamily: Translation proteins
Family: Ribosomal protein L3

Phyre2

PDB 2gyc chain B domain 1

3D model

Region: 43 - 352
Aligned: 205
Modelled: 214
Confidence: 100.0%
Identity: 25%
Fold: Reductase/isomerase/elongation factor common domain
Superfamily: Translation proteins
Family: Ribosomal protein L3

Phyre2

PDB 2zjr chain B domain 1

3D model

Region: 43 - 354
Aligned: 202
Modelled: 214
Confidence: 100.0%
Identity: 25%
Fold: Reductase/isomerase/elongation factor common domain
Superfamily: Translation proteins
Family: Ribosomal protein L3

Phyre2

PDB 2j01 chain E domain 1

3D model

Region: 43 - 352
Aligned: 200
Modelled: 212
Confidence: 100.0%
Identity: 29%
Fold: Reductase/isomerase/elongation factor common domain
Superfamily: Translation proteins
Family: Ribosomal protein L3

Phyre2

PDB 2ftc chain C

3D model

Region: 44 - 354
Aligned: 208
Modelled: 219
Confidence: 100.0%
Identity: 21%
PDB header:ribosome
Chain: C: PDB Molecule:mitochondrial 39s ribosomal protein l3;
PDBTitle: structural model for the large subunit of the mammalian mitochondrial2 ribosome

Phyre2

PDB 3bbo chain F

3D model

Region: 134 - 353
Aligned: 152
Modelled: 152
Confidence: 100.0%
Identity: 29%
PDB header:ribosome
Chain: F: PDB Molecule:ribosomal protein l3;
PDBTitle: homology model for the spinach chloroplast 50s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome

Phyre2

PDB 3ryk chain B

3D model

Region: 52 - 95
Aligned: 44
Modelled: 44
Confidence: 59.7%
Identity: 18%
PDB header:isomerase
Chain: B: PDB Molecule:dtdp-4-dehydrorhamnose 3,5-epimerase;
PDBTitle: 1.63 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 3,5-epimerase (rfbc) from bacillus anthracis str. ames with tdp and3 ppi bound

Phyre2

PDB 1ep0 chain A

3D model

Region: 51 - 95
Aligned: 45
Modelled: 45
Confidence: 46.8%
Identity: 13%
Fold: Double-stranded beta-helix
Superfamily: RmlC-like cupins
Family: dTDP-sugar isomerase

Phyre2

PDB 1upi chain A

3D model

Region: 52 - 95
Aligned: 44
Modelled: 44
Confidence: 42.7%
Identity: 14%
PDB header:epimerase
Chain: A: PDB Molecule:dtdp-4-dehydrorhamnose 3,5-epimerase;
PDBTitle: mycobacterium tuberculosis rmlc epimerase (rv3465)

Phyre2

PDB 1wlt chain A domain 1

3D model

Region: 52 - 95
Aligned: 44
Modelled: 44
Confidence: 41.9%
Identity: 20%
Fold: Double-stranded beta-helix
Superfamily: RmlC-like cupins
Family: dTDP-sugar isomerase

Phyre2

PDB 1dzr chain A

3D model

Region: 52 - 95
Aligned: 44
Modelled: 44
Confidence: 41.4%
Identity: 20%
Fold: Double-stranded beta-helix
Superfamily: RmlC-like cupins
Family: dTDP-sugar isomerase

Phyre2

PDB 1oi6 chain A

3D model

Region: 52 - 95
Aligned: 44
Modelled: 44
Confidence: 35.5%
Identity: 18%
Fold: Double-stranded beta-helix
Superfamily: RmlC-like cupins
Family: dTDP-sugar isomerase

Phyre2

PDB 2ixc chain A domain 1

3D model

Region: 51 - 95
Aligned: 45
Modelled: 45
Confidence: 34.9%
Identity: 13%
Fold: Double-stranded beta-helix
Superfamily: RmlC-like cupins
Family: dTDP-sugar isomerase

Phyre2

PDB 2qtx chain L

3D model

Region: 194 - 223
Aligned: 28
Modelled: 30
Confidence: 34.4%
Identity: 29%
PDB header:rna binding protein
Chain: L: PDB Molecule:uncharacterized protein mj1435;
PDBTitle: crystal structure of an hfq-like protein from methanococcus2 jannaschii

Phyre2

PDB 2c0z chain A

3D model

Region: 52 - 95
Aligned: 44
Modelled: 44
Confidence: 33.1%
Identity: 16%
PDB header:isomerase
Chain: A: PDB Molecule:novw;
PDBTitle: the 1.6 a resolution crystal structure of novw: a 4-keto-6-2 deoxy sugar epimerase from the novobiocin biosynthetic3 gene cluster of streptomyces spheroides

Phyre2
1

c3iz5C_
2

c4a1aB_
3

c3jywC_
4

c2zkrb_
5

c1s1iC_
6

d1vqob1
7

d2gycb1
8

d2zjrb1
9

d2j01e1
10

c2ftcC_
11

c3bboF_
12

c3rykB_
13

d1ep0a_
14

c1upiA_
15

d1wlta1
16

d1dzra_
17

d1oi6a_
18

d2ixca1
19

c2qtxL_
20

c2c0zA_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3iz5C_



100.0 68 PDB header:ribosome
Chain: C: PDB Molecule:60s ribosomal protein l3 (l3p);
PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
2c4a1aB_



100.0 63 PDB header:ribosome
Chain: B: PDB Molecule:ribosomal protein l3;
PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 5s rrna,3 5.8s rrna and proteins of molecule 3.
3c3jywC_



100.0 67 PDB header:ribosome
Chain: C: PDB Molecule:60s ribosomal protein l3;
PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution
4c2zkrb_



100.0 98 PDB header:ribosomal protein/rna
Chain: B: PDB Molecule:rna expansion segment es4;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
5c1s1iC_



100.0 67 PDB header:ribosome
Chain: C: PDB Molecule:60s ribosomal protein l3;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1i,4 contains 60s subunit. the 40s ribosomal subunit is in file5 1s1h.
6d1vqob1



100.0 37 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Translation proteins
Family:Ribosomal protein L3
7d2gycb1



100.0 25 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Translation proteins
Family:Ribosomal protein L3
8d2zjrb1



100.0 25 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Translation proteins
Family:Ribosomal protein L3
9d2j01e1



100.0 29 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Translation proteins
Family:Ribosomal protein L3
10c2ftcC_



100.0 21 PDB header:ribosome
Chain: C: PDB Molecule:mitochondrial 39s ribosomal protein l3;
PDBTitle: structural model for the large subunit of the mammalian mitochondrial2 ribosome
11c3bboF_



100.0 29 PDB header:ribosome
Chain: F: PDB Molecule:ribosomal protein l3;
PDBTitle: homology model for the spinach chloroplast 50s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome
12c3rykB_



59.7 18 PDB header:isomerase
Chain: B: PDB Molecule:dtdp-4-dehydrorhamnose 3,5-epimerase;
PDBTitle: 1.63 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 3,5-epimerase (rfbc) from bacillus anthracis str. ames with tdp and3 ppi bound
13d1ep0a_



46.8 13 Fold:Double-stranded beta-helix
Superfamily:RmlC-like cupins
Family:dTDP-sugar isomerase
14c1upiA_



42.7 14 PDB header:epimerase
Chain: A: PDB Molecule:dtdp-4-dehydrorhamnose 3,5-epimerase;
PDBTitle: mycobacterium tuberculosis rmlc epimerase (rv3465)
15d1wlta1



41.9 20 Fold:Double-stranded beta-helix
Superfamily:RmlC-like cupins
Family:dTDP-sugar isomerase
16d1dzra_



41.4 20 Fold:Double-stranded beta-helix
Superfamily:RmlC-like cupins
Family:dTDP-sugar isomerase
17d1oi6a_



35.5 18 Fold:Double-stranded beta-helix
Superfamily:RmlC-like cupins
Family:dTDP-sugar isomerase
18d2ixca1



34.9 13 Fold:Double-stranded beta-helix
Superfamily:RmlC-like cupins
Family:dTDP-sugar isomerase
19c2qtxL_



34.4 29 PDB header:rna binding protein
Chain: L: PDB Molecule:uncharacterized protein mj1435;
PDBTitle: crystal structure of an hfq-like protein from methanococcus2 jannaschii
20c2c0zA_



33.1 16 PDB header:isomerase
Chain: A: PDB Molecule:novw;
PDBTitle: the 1.6 a resolution crystal structure of novw: a 4-keto-6-2 deoxy sugar epimerase from the novobiocin biosynthetic3 gene cluster of streptomyces spheroides
21c3ejkA_



not modelled 31.0 27 PDB header:isomerase
Chain: A: PDB Molecule:dtdp sugar isomerase;
PDBTitle: crystal structure of dtdp sugar isomerase (yp_390184.1) from2 desulfovibrio desulfuricans g20 at 1.95 a resolution
22d2c0za1



not modelled 30.1 16 Fold:Double-stranded beta-helix
Superfamily:RmlC-like cupins
Family:dTDP-sugar isomerase
23d2ixha1



not modelled 27.8 25 Fold:Double-stranded beta-helix
Superfamily:RmlC-like cupins
Family:dTDP-sugar isomerase
24d1xhca3



not modelled 13.5 45 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
25d1ekga_



not modelled 11.9 24 Fold:N domain of copper amine oxidase-like
Superfamily:Frataxin/Nqo15-like
Family:Frataxin-like
26c1vbiA_



not modelled 8.3 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase;
PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8
27d1vqoq1



not modelled 8.1 22 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:Ribosomal proteins L24p and L21e
28c1htmB_



not modelled 7.5 43 PDB header:viral protein
Chain: B: PDB Molecule:hemagglutinin ha2 chain;
PDBTitle: structure of influenza haemagglutinin at the ph of membrane2 fusion
29d1inva_



not modelled 6.8 36 Fold:6-bladed beta-propeller
Superfamily:Sialidases
Family:Sialidases (neuraminidases)
30c3ij2B_



not modelled 6.7 16 PDB header:hormone/protein binding
Chain: B: PDB Molecule:beta-nerve growth factor;
PDBTitle: ligand-receptor structure
31c1s1iQ_



not modelled 6.7 20 PDB header:ribosome
Chain: Q: PDB Molecule:60s ribosomal protein l21-a;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1i,4 contains 60s subunit. the 40s ribosomal subunit is in file5 1s1h.
32d1bndb_



not modelled 6.7 14 Fold:Cystine-knot cytokines
Superfamily:Cystine-knot cytokines
Family:Neurotrophin
33c2zkrq_



not modelled 6.7 10 PDB header:ribosomal protein/rna
Chain: Q: PDB Molecule:rna expansion segment es31 part ii;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
34d1wwwv_



not modelled 6.5 21 Fold:Cystine-knot cytokines
Superfamily:Cystine-knot cytokines
Family:Neurotrophin
35d2gqfa1



not modelled 6.4 26 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:HI0933 N-terminal domain-like
36c1zuyB_



not modelled 6.4 7 PDB header:contractile protein
Chain: B: PDB Molecule:myosin-5 isoform;
PDBTitle: high-resolution structure of yeast myo5 sh3 domain
37c1a3qA_



not modelled 6.2 21 PDB header:transcription/dna
Chain: A: PDB Molecule:protein (nuclear factor kappa-b p52);
PDBTitle: human nf-kappa-b p52 bound to dna
38c2rqrA_



not modelled 6.0 0 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
39c2eg9B_



not modelled 5.8 14 PDB header:hydrolase
Chain: B: PDB Molecule:adp-ribosyl cyclase 1;
PDBTitle: crystal structure of the truncated extracellular domain of2 mouse cd38
40d1b7go1



not modelled 5.8 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
41c3hfkB_



not modelled 5.7 20 PDB header:isomerase
Chain: B: PDB Molecule:4-methylmuconolactone methylisomerase;
PDBTitle: crystal structure of 4-methylmuconolactone methylisomerase2 (h52a) in complex with 4-methylmuconolactone
42d1t11a3



not modelled 5.6 16 Fold:FKBP-like
Superfamily:FKBP-like
Family:FKBP immunophilin/proline isomerase
43d1jjga_



not modelled 5.5 8 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
44c3fq6A_



not modelled 5.4 45 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: the crystal structure of a methyltransferase domain from bacteroides2 thetaiotaomicron vpi
45c3iz5O_



not modelled 5.4 26 PDB header:ribosome
Chain: O: PDB Molecule:60s ribosomal protein l27a (l15p);
PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
46d1s1da_



not modelled 5.4 17 Fold:5-bladed beta-propeller
Superfamily:Apyrase
Family:Apyrase
47c3fyfA_



not modelled 5.2 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:protein bvu-3222;
PDBTitle: crystal structure of uncharacterized protein bvu_3222 from2 bacteroides vulgatus

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite