Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionO75791
DateWed May 9 17:39:07 BST 2012
Unique Job ID98b238c746de9cd9

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1griA_
Top template information
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
Confidence and coverage
Confidence:100.0% Coverage: 63%
208 residues ( 63% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFH
Secondary structure 






































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Disorder  ??










?????




















?
??














??
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   .........70.........80.........90.........100.........110.........120
Sequence  EGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTE
Secondary structure 






















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Disorder  ????










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?






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   .........130.........140.........150.........160.........170.........180
Sequence  KFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEEIRP
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Disorder 




























???














?????????????
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   .........190.........200.........210.........220.........230.........240
Sequence  SMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPPQQRYLQHHHFHQERRGGSLDIN
Secondary structure 



























































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Disorder  ?
???
??????????????????????????????????????????????????????
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   .........250.........260.........270.........280.........290.........300
Sequence  DGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEV
Secondary structure 
















































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Disorder 
???????????????????????
?
?????













????









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   .........310.........320.........330
Sequence  LDSSNPSWWTGRLHNKLGLFPANYVAPMTR
Secondary structure 








SS confidence 





























Disorder 


























???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1gri chain A

3D model

Region: 1 - 330
Aligned: 208
Modelled: 212
Confidence: 100.0%
Identity: 60%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 2lqn chain A

3D model

Region: 1 - 328
Aligned: 165
Modelled: 165
Confidence: 100.0%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2l3s chain A

3D model

Region: 2 - 330
Aligned: 159
Modelled: 159
Confidence: 100.0%
Identity: 26%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 2eyz chain A

3D model

Region: 2 - 329
Aligned: 158
Modelled: 158
Confidence: 100.0%
Identity: 28%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 1ng2 chain A

3D model

Region: 2 - 328
Aligned: 123
Modelled: 123
Confidence: 100.0%
Identity: 32%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2

PDB 1ov3 chain A

3D model

Region: 2 - 326
Aligned: 121
Modelled: 121
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 1mv3 chain A

3D model

Region: 134 - 328
Aligned: 195
Modelled: 195
Confidence: 99.9%
Identity: 13%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 2eyy chain A

3D model

Region: 48 - 330
Aligned: 189
Modelled: 189
Confidence: 99.9%
Identity: 27%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i

Phyre2

PDB 1ng2 chain A domain 2

3D model

Region: 261 - 330
Aligned: 70
Modelled: 70
Confidence: 99.8%
Identity: 24%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 1k9a chain B

3D model

Region: 1 - 137
Aligned: 137
Modelled: 137
Confidence: 99.8%
Identity: 34%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 1opl chain A

3D model

Region: 3 - 164
Aligned: 162
Modelled: 162
Confidence: 99.8%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 2fo0 chain A

3D model

Region: 3 - 137
Aligned: 135
Modelled: 135
Confidence: 99.8%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 2c0i chain A

3D model

Region: 3 - 138
Aligned: 136
Modelled: 136
Confidence: 99.8%
Identity: 38%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 2dx1 chain A

3D model

Region: 275 - 329
Aligned: 55
Modelled: 55
Confidence: 99.8%
Identity: 44%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 1x27 chain F

3D model

Region: 3 - 137
Aligned: 135
Modelled: 135
Confidence: 99.8%
Identity: 38%
PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas

Phyre2

PDB 2dyb chain A

3D model

Region: 2 - 321
Aligned: 142
Modelled: 142
Confidence: 99.8%
Identity: 32%
PDB header:oxidoreductase
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: the crystal structure of human p40(phox)

Phyre2

PDB 2dvj chain A

3D model

Region: 48 - 329
Aligned: 188
Modelled: 188
Confidence: 99.8%
Identity: 29%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii

Phyre2

PDB 2cub chain A

3D model

Region: 258 - 330
Aligned: 73
Modelled: 73
Confidence: 99.8%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1

Phyre2

PDB 1y57 chain A

3D model

Region: 3 - 138
Aligned: 136
Modelled: 136
Confidence: 99.8%
Identity: 32%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 2h8h chain A

3D model

Region: 3 - 138
Aligned: 136
Modelled: 136
Confidence: 99.8%
Identity: 32%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2
1

c1griA_
2

c2lqnA_
3

c2l3sA_
4

c2eyzA_
5

c1ng2A_
6

c1ov3A_
7

c1mv3A_
8

c2eyyA_
9

d1ng2a2
10

c1k9aB_
11

c1oplA_
12

c2fo0A_
13

c2c0iA_
14

c2dx1A_
15

c1x27F_
16

c2dybA_
17

c2dvjA_
18

c2cubA_
19

c1y57A_
20

c2h8hA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1griA_



100.0 60 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
2c2lqnA_



100.0 25 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
3c2l3sA_



100.0 26 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
4c2eyzA_



100.0 28 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
5c1ng2A_



100.0 32 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
6c1ov3A_



100.0 33 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
7c1mv3A_



99.9 13 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
8c2eyyA_



99.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
9d1ng2a2



99.8 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
10c1k9aB_



99.8 34 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
11c1oplA_



99.8 33 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
12c2fo0A_



99.8 36 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
13c2c0iA_



99.8 38 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
14c2dx1A_



99.8 44 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
15c1x27F_



99.8 38 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
16c2dybA_



99.8 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: the crystal structure of human p40(phox)
17c2dvjA_



99.8 29 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
18c2cubA_



99.8 23 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
19c1y57A_



99.8 32 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
20c2h8hA_



99.8 32 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
21d1ov3a2



not modelled 99.8 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
22c3nmzD_



not modelled 99.8 36 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
23c2fpeB_



not modelled 99.8 25 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
24c2dmoA_



not modelled 99.8 29 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
25c2ed0A_



not modelled 99.8 25 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
26c2df6A_



not modelled 99.8 33 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
27c2ablA_



not modelled 99.8 37 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
28c2yunA_



not modelled 99.8 37 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
29d1sema_



not modelled 99.8 41 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
30c2xmfA_



not modelled 99.8 37 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
31c1zx6A_



not modelled 99.8 38 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
32c2yuoA_



not modelled 99.8 33 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
33c2yt6A_



not modelled 99.8 28 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
34c2rqrA_



not modelled 99.8 13 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
35d1utia_



not modelled 99.8 96 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
36c2bz8B_



not modelled 99.8 25 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
37d1gria2



not modelled 99.8 46 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
38d1oeba_



not modelled 99.8 92 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
39c2dlpA_



not modelled 99.8 27 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
40c3nhnA_



not modelled 99.8 38 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
41c2dl4A_



not modelled 99.8 30 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
42d1gcqa_



not modelled 99.8 48 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
43c1x2qA_



not modelled 99.8 41 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
44d1uuea_



not modelled 99.8 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
45d1wlpb2



not modelled 99.8 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
46c2nwmA_



not modelled 99.8 36 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
47c2dilA_



not modelled 99.8 28 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
48c2ct3A_



not modelled 99.8 32 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
49c2djqA_



not modelled 99.8 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
50c2oi3A_



not modelled 99.8 29 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
51d1pwta_



not modelled 99.8 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
52c2pqhA_



not modelled 99.8 28 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal
53c2csqA_



not modelled 99.8 24 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
54c2dl3A_



not modelled 99.8 29 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
55d1k4us_



not modelled 99.8 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
56c2l0aA_



not modelled 99.8 46 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
57d1udla_



not modelled 99.8 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
58c2kymA_



not modelled 99.8 31 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
59c2cudA_



not modelled 99.8 18 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
60c2epdA_



not modelled 99.8 24 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
61c2ysqA_



not modelled 99.8 32 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
62d1j3ta_



not modelled 99.8 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
63c2dnuA_



not modelled 99.8 25 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
64c2jxbA_



not modelled 99.8 24 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
65c2ebpA_



not modelled 99.8 26 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
66d1e6ga_



not modelled 99.8 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
67d1u06a1



not modelled 99.8 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
68d1ue9a_



not modelled 99.8 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
69c2drmB_



not modelled 99.8 40 PDB header:contractile protein
Chain: B: PDB Molecule:acanthamoeba myosin ib;
PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
70c1wi7A_



not modelled 99.8 27 PDB header:protein binding
Chain: A: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: solution structure of the sh3 domain of sh3-domain kinase2 binding protein 1
71c1x69A_



not modelled 99.8 29 PDB header:signaling protein
Chain: A: PDB Molecule:cortactin isoform a;
PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin
72c2eyxA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
73c2azsA_



not modelled 99.8 46 PDB header:signaling protein
Chain: A: PDB Molecule:sh2-sh3 adapter protein drk;
PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints)
74d1nega_



not modelled 99.8 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
75c1negA_



not modelled 99.8 28 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin
76d1ujya_



not modelled 99.8 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
77c2dl8A_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
78c2ekhA_



not modelled 99.8 20 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
79c1x2pA_



not modelled 99.7 25 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 2;
PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
80c2dbmA_



not modelled 99.7 35 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:sh3-containing grb2-like protein 2;
PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2
81c2egeA_



not modelled 99.7 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein kiaa1666;
PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
82c1w70A_



not modelled 99.7 32 PDB header:sh3 domain
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
83d1e6ha_



not modelled 99.7 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
84c2dbkA_



not modelled 99.7 20 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
85c2egaA_



not modelled 99.7 22 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein
86d1h8ka_



not modelled 99.7 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
87c1zlmA_



not modelled 99.7 45 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
88c2e5kA_



not modelled 99.7 21 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
89c1x43A_



not modelled 99.7 27 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
90c1x6bA_



not modelled 99.7 22 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
91c3rnjA_



not modelled 99.7 20 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)
92c2krnA_



not modelled 99.7 38 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: high resolution structure of the second sh3 domain of cd2ap
93c2i0nA_



not modelled 99.7 25 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
94c2yupA_



not modelled 99.7 26 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
95c2d1xD_



not modelled 99.7 37 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
96c2ed1A_



not modelled 99.7 33 PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
97d1ov3a1



not modelled 99.7 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
98c1x6gA_



not modelled 99.7 18 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
99c2eqiA_



not modelled 99.7 30 PDB header:immune system, hydrolase
Chain: A: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2
100d1uhfa_



not modelled 99.7 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
101c2cucA_



not modelled 99.7 30 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2
102c2o2oA_



not modelled 99.7 27 PDB header:protein binding
Chain: A: PDB Molecule:sh3-domain kinase-binding protein 1;
PDBTitle: solution structure of domain b from human cin85 protein
103c2rf0D_



not modelled 99.7 45 PDB header:transferase
Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10;
PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
104c1wyxA_



not modelled 99.7 36 PDB header:cell adhesion
Chain: A: PDB Molecule:crk-associated substrate;
PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
105d1uj0a_



not modelled 99.7 56 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
106d1wfwa_



not modelled 99.7 22 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
107c1g83A_



not modelled 99.7 37 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
108c2kbtA_



not modelled 99.7 32 PDB header:signaling protein
Chain: A: PDB Molecule:chimera of proto-oncogene vav, linker,
PDBTitle: attachment of an nmr-invisible solubility enhancement tag2 (inset) using a sortase-mediated protein ligation method
109c2dl7A_



not modelled 99.7 30 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:kiaa0769 protein;
PDBTitle: solution structure of the second sh3 domain of human2 kiaa0769 protein
110c1zukA_



not modelled 99.7 21 PDB header:contractile protein
Chain: A: PDB Molecule:myosin tail region-interacting protein mti1;
PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17
111c1bb9A_



not modelled 99.7 28 PDB header:transferase
Chain: A: PDB Molecule:amphiphysin 2;
PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2
112d1bb9a_



not modelled 99.7 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
113c3qwxX_



not modelled 99.7 25 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
114c3cqtA_



not modelled 99.7 44 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: n53i v55l mutant of fyn sh3 domain
115c3qwyA_



not modelled 99.7 26 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
116d1ug1a_



not modelled 99.7 18 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
117c2j6kE_



not modelled 99.7 27 PDB header:protein binding
Chain: E: PDB Molecule:cd2-associated protein;
PDBTitle: n-terminal sh3 domain of cms (cd2ap human homolog)
118c2jteA_



not modelled 99.7 31 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: third sh3 domain of cd2ap
119d1uhca_



not modelled 99.7 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
120c2ke9A_



not modelled 99.7 29 PDB header:protein binding
Chain: A: PDB Molecule:caskin-2;
PDBTitle: nmr solution structure of the caskin sh3 domain

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