Phyre 2 Results for A0PK11

Email	l.a.kelley@imperial.ac.uk
Description	A0PK11
Date	Fri May 25 09:41:56 BST 2012
Unique Job ID	dadc965393d3d0c9

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2kncA_

Top template information

PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Confidence and coverage

Confidence:

43.2%

Coverage:

17%

39 residues ( 17% of your sequence) have been modelled with 43.2% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

Please note: You must be registered and logged in to use Phyrealarm.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M P G W F K K A W Y G L A S L L S F S S F I L I I V A L V V P H W L S G K I L C Q T G V D L V N A T D R E L V K F I G D

Secondary structure

SS confidence

Disorder ? ? ?
? ?
? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence I Y Y G L F R G C K V R Q C G L G G R Q S Q F T I F P H L V K E L N A G L H V M I L L L L F L A L A L A L V S M G F A I

Secondary structure

SS confidence

Disorder
?
? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence L N M I Q V P Y R A V S G P G G I C L W N V L A G G V V A L A I A S F V A A V K F H D L T E R I A N F Q E K L F Q F V V

Secondary structure

SS confidence

Disorder
?
? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . .

Sequence V E E Q Y E E S F W I C V A S A S A H A A N L V V V A I S Q I P L P E I K T K I E E A T V T A E D I L Y

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2knc chain A

Region: 190 - 228
Aligned: 39
Modelled: 39
Confidence: 43.2%
Identity: 15%
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2

PDB 2jo1 chain A

Region: 192 - 226
Aligned: 35
Modelled: 35
Confidence: 35.7%
Identity: 9%
PDB header:hydrolase regulator
Chain: A: PDB Molecule:phospholemman;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles

Phyre2

PDB 2jp3 chain A

Region: 192 - 223
Aligned: 32
Modelled: 32
Confidence: 28.7%
Identity: 6%
PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles

Phyre2

PDB 1rzh chain H domain 2

Region: 187 - 200
Aligned: 14
Modelled: 14
Confidence: 27.8%
Identity: 36%
Fold: Single transmembrane helix
Superfamily: Photosystem II reaction centre subunit H, transmembrane region
Family: Photosystem II reaction centre subunit H, transmembrane region

Phyre2

PDB 1l9b chain H domain 2

Region: 187 - 200
Aligned: 14
Modelled: 14
Confidence: 26.4%
Identity: 36%
Fold: Single transmembrane helix
Superfamily: Photosystem II reaction centre subunit H, transmembrane region
Family: Photosystem II reaction centre subunit H, transmembrane region

Phyre2

PDB 2l8s chain A

Region: 190 - 224
Aligned: 35
Modelled: 35
Confidence: 17.3%
Identity: 23%
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-1;
PDBTitle: solution nmr structure of transmembrane and cytosolic regions of2 integrin alpha1 in detergent micelles

Phyre2

PDB 2rcr chain H domain 2

Region: 187 - 200
Aligned: 14
Modelled: 14
Confidence: 17.3%
Identity: 36%
Fold: Single transmembrane helix
Superfamily: Photosystem II reaction centre subunit H, transmembrane region
Family: Photosystem II reaction centre subunit H, transmembrane region

Phyre2

PDB 3t47 chain A

Region: 119 - 127
Aligned: 9
Modelled: 9
Confidence: 12.9%
Identity: 44%
PDB header:immune system
Chain: A: PDB Molecule:scin-d;
PDBTitle: crystal structure of truncated form of staphylococcal complement2 inhibitor d (scin-d) at 1.3 angstrom

Phyre2

PDB 3hd6 chain A

Region: 107 - 228
Aligned: 103
Modelled: 103
Confidence: 10.8%
Identity: 15%
PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:ammonium transporter rh type c;
PDBTitle: crystal structure of the human rhesus glycoprotein rhcg

Phyre2

PDB 2k1a chain A

Region: 190 - 219
Aligned: 30
Modelled: 30
Confidence: 10.0%
Identity: 10%
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: bicelle-embedded integrin alpha(iib) transmembrane segment

Phyre2

PDB 2b2h chain A

Region: 108 - 228
Aligned: 110
Modelled: 121
Confidence: 9.8%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:ammonium transporter;
PDBTitle: ammonium transporter amt-1 from a. fulgidus (as)

Phyre2

PDB 3qnq chain D

Region: 186 - 228
Aligned: 43
Modelled: 43
Confidence: 9.4%
Identity: 14%
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Phyre2

PDB 1eys chain H domain 2

Region: 187 - 200
Aligned: 14
Modelled: 14
Confidence: 6.2%
Identity: 14%
Fold: Single transmembrane helix
Superfamily: Photosystem II reaction centre subunit H, transmembrane region
Family: Photosystem II reaction centre subunit H, transmembrane region

Phyre2

PDB 1pw4 chain A

Region: 93 - 222
Aligned: 106
Modelled: 108
Confidence: 5.4%
Identity: 12%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: Glycerol-3-phosphate transporter

Phyre2

PDB 2p7t chain C domain 1

Region: 15 - 33
Aligned: 17
Modelled: 19
Confidence: 5.2%
Identity: 35%
Fold: Voltage-gated potassium channels
Superfamily: Voltage-gated potassium channels
Family: Voltage-gated potassium channels

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	P	G	W	F	K	K	A	W	Y	G	L	A	S	L	L	S	F	S	S	F	I	L	I	I	V	A	L	V	V	P	H	W	L	S	G	K	I	L	C	Q	T	G	V	D	L	V	N	A	T	D	R	E	L	V	K	F	I	G	D
Secondary structure
SS confidence
Disorder	?	?	?																											?	?										?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	I	Y	Y	G	L	F	R	G	C	K	V	R	Q	C	G	L	G	G	R	Q	S	Q	F	T	I	F	P	H	L	V	K	E	L	N	A	G	L	H	V	M	I	L	L	L	L	F	L	A	L	A	L	A	L	V	S	M	G	F	A	I
Secondary structure
SS confidence
Disorder																													?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	L	N	M	I	Q	V	P	Y	R	A	V	S	G	P	G	G	I	C	L	W	N	V	L	A	G	G	V	V	A	L	A	I	A	S	F	V	A	A	V	K	F	H	D	L	T	E	R	I	A	N	F	Q	E	K	L	F	Q	F	V	V
Secondary structure
SS confidence
Disorder			?																																																			?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
Sequence	V	E	E	Q	Y	E	E	S	F	W	I	C	V	A	S	A	S	A	H	A	A	N	L	V	V	V	A	I	S	Q	I	P	L	P	E	I	K	T	K	I	E	E	A	T	V	T	A	E	D	I	L	Y
Secondary structure
SS confidence
Disorder																															?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence