Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA0PK05
DateFri May 25 09:56:38 BST 2012
Unique Job ID7c7232123247cf01

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2zxeG_
Top template information
PDB header:hydrolase/transport protein
Chain: G: PDB Molecule:phospholemman-like protein;
PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state
Confidence and coverage
Confidence: 58.5% Coverage: 9%
26 residues ( 9% of your sequence) have been modelled with 58.5% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MQLQVFWTGLEYTCRLLGITTAAVLIGVGTETFLQGQFKSLAFYLLFTGAAVSICEGAYF
Secondary structure 






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   .........70.........80.........90.........100.........110.........120
Sequence  VAQLLAICFQCQPGSLADRVREKAHWLGCFQKFLAYLLLSVACFLHPVLVWHVTIPGSML
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   .........130.........140.........150.........160.........170.........180
Sequence  IITGLAYFLLSKRKKRKAAPEVLASPEQYTDPSSSAVSTTGSGDTEQTYTFHGALKEGPS
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????????







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?
??
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   .........190.........200.........210.........220.........230.........240
Sequence  SLFIHMKSILKGTKKPSALQPPNTLMELSLEPADSLAKKKQVHFEDNLVRIVPSLAEGLD
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??????????????????????????????????
?


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   .........250.........260.........270.....
Sequence  DGDSEPEETTSDTTPIIPPPQAPLFLSSLTATGLF
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Disorder  ?????????????






??


??
???????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2zxe chain G

3D model

Region: 11 - 36
Aligned: 26
Modelled: 26
Confidence: 58.5%
Identity: 38%
PDB header:hydrolase/transport protein
Chain: G: PDB Molecule:phospholemman-like protein;
PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state

Phyre2

PDB 2jp3 chain A

3D model

Region: 15 - 39
Aligned: 25
Modelled: 25
Confidence: 45.5%
Identity: 28%
PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles

Phyre2

PDB 2jo1 chain A

3D model

Region: 13 - 39
Aligned: 27
Modelled: 27
Confidence: 45.1%
Identity: 19%
PDB header:hydrolase regulator
Chain: A: PDB Molecule:phospholemman;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles

Phyre2

PDB 3n23 chain E

3D model

Region: 11 - 35
Aligned: 25
Modelled: 25
Confidence: 32.8%
Identity: 32%
PDB header:hydrolase
Chain: E: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of the high affinity complex between ouabain and the2 e2p form of the sodium-potassium pump

Phyre2

PDB 1v3a chain A

3D model

Region: 172 - 238
Aligned: 60
Modelled: 67
Confidence: 19.9%
Identity: 12%
Fold: (Phosphotyrosine protein) phosphatases II
Superfamily: (Phosphotyrosine protein) phosphatases II
Family: Dual specificity phosphatase-like

Phyre2

PDB 3mk7 chain F

3D model

Region: 111 - 149
Aligned: 39
Modelled: 39
Confidence: 19.3%
Identity: 21%
PDB header:oxidoreductase
Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p;
PDBTitle: the structure of cbb3 cytochrome oxidase

Phyre2

PDB 2hey chain R domain 1

3D model

Region: 66 - 74
Aligned: 9
Modelled: 9
Confidence: 16.8%
Identity: 44%
Fold: TNF receptor-like
Superfamily: TNF receptor-like
Family: TNF receptor-like

Phyre2

PDB 3kk4 chain B

3D model

Region: 4 - 41
Aligned: 38
Modelled: 38
Confidence: 16.6%
Identity: 26%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein bp1543;
PDBTitle: uncharacterized protein bp1543 from bordetella pertussis tohama i

Phyre2

PDB 1dzl chain A

3D model

Region: 135 - 161
Aligned: 27
Modelled: 27
Confidence: 15.3%
Identity: 30%
Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily: Group I dsDNA viruses
Family: Papovaviridae-like VP

Phyre2

PDB 1dzl chain A

3D model

Region: 135 - 161
Aligned: 27
Modelled: 27
Confidence: 15.3%
Identity: 30%
PDB header:virus
Chain: A: PDB Molecule:late major capsid protein l1;
PDBTitle: l1 protein of human papillomavirus 16

Phyre2

PDB 1u24 chain A

3D model

Region: 169 - 221
Aligned: 53
Modelled: 53
Confidence: 14.9%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:myo-inositol hexaphosphate phosphohydrolase;
PDBTitle: crystal structure of selenomonas ruminantium phytase

Phyre2

PDB 1vjq chain B

3D model

Region: 216 - 274
Aligned: 55
Modelled: 59
Confidence: 13.8%
Identity: 27%
PDB header:structural genomics, de novo protein
Chain: B: PDB Molecule:designed protein;
PDBTitle: designed protein based on backbone conformation of2 procarboxypeptidase-a (1aye) with sidechains chosen for maximal3 predicted stability.

Phyre2

PDB 2blc chain A

3D model

Region: 66 - 72
Aligned: 7
Modelled: 7
Confidence: 12.1%
Identity: 57%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase;
PDBTitle: sp21 double mutant p. vivax dihydrofolate reductase in2 complex with des-chloropyrimethamine

Phyre2

PDB 2eps chain A domain 1

3D model

Region: 177 - 194
Aligned: 18
Modelled: 18
Confidence: 11.0%
Identity: 22%
Fold: beta-beta-alpha zinc fingers
Superfamily: beta-beta-alpha zinc fingers
Family: Classic zinc finger, C2H2

Phyre2

PDB 3tre chain A

3D model

Region: 168 - 216
Aligned: 48
Modelled: 47
Confidence: 10.4%
Identity: 10%
PDB header:translation
Chain: A: PDB Molecule:elongation factor p;
PDBTitle: structure of a translation elongation factor p (efp) from coxiella2 burnetii

Phyre2

PDB 2r5i chain L

3D model

Region: 145 - 161
Aligned: 17
Modelled: 17
Confidence: 10.3%
Identity: 29%
PDB header:viral protein
Chain: L: PDB Molecule:l1 protein;
PDBTitle: pentamer structure of major capsid protein l1 of human2 papilloma virus type 18

Phyre2

PDB 1j3k chain A

3D model

Region: 66 - 72
Aligned: 7
Modelled: 7
Confidence: 10.1%
Identity: 57%
Fold: Dihydrofolate reductase-like
Superfamily: Dihydrofolate reductase-like
Family: Dihydrofolate reductases

Phyre2

PDB 3dg8 chain B

3D model

Region: 66 - 72
Aligned: 7
Modelled: 7
Confidence: 10.1%
Identity: 57%
PDB header:oxidoreductase, transferase
Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate
PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump

Phyre2

PDB 2kwz chain A

3D model

Region: 98 - 129
Aligned: 30
Modelled: 32
Confidence: 9.8%
Identity: 33%
PDB header:viral protein
Chain: A: PDB Molecule:protease ns2-3;
PDBTitle: solution structure of ns2 [60-99]

Phyre2

PDB 2kr6 chain A

3D model

Region: 93 - 140
Aligned: 48
Modelled: 48
Confidence: 9.7%
Identity: 29%
PDB header:hydrolase
Chain: A: PDB Molecule:presenilin-1;
PDBTitle: solution structure of presenilin-1 ctf subunit

Phyre2
1

c2zxeG_
2

c2jp3A_
3

c2jo1A_
4

c3n23E_
5

d1v3aa_
6

c3mk7F_
7

d2heyr1
8

c3kk4B_
9

d1dzla_
10

c1dzlA_
11

c1u24A_
12

c1vjqB_
13

c2blcA_
14

d2epsa1
15

c3treA_
16

c2r5iL_
17

d1j3ka_
18

c3dg8B_
19

c2kwzA_
20

c2kr6A_
21



22



23



24



25



26



27



28



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31



32



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35



36



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51



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53






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2zxeG_



58.5 38 PDB header:hydrolase/transport protein
Chain: G: PDB Molecule:phospholemman-like protein;
PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state
2c2jp3A_



45.5 28 PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles
3c2jo1A_



45.1 19 PDB header:hydrolase regulator
Chain: A: PDB Molecule:phospholemman;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles
4c3n23E_



32.8 32 PDB header:hydrolase
Chain: E: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of the high affinity complex between ouabain and the2 e2p form of the sodium-potassium pump
5d1v3aa_



19.9 12 Fold:(Phosphotyrosine protein) phosphatases II
Superfamily:(Phosphotyrosine protein) phosphatases II
Family:Dual specificity phosphatase-like
6c3mk7F_



19.3 21 PDB header:oxidoreductase
Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p;
PDBTitle: the structure of cbb3 cytochrome oxidase
7d2heyr1



16.8 44 Fold:TNF receptor-like
Superfamily:TNF receptor-like
Family:TNF receptor-like
8c3kk4B_



16.6 26 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein bp1543;
PDBTitle: uncharacterized protein bp1543 from bordetella pertussis tohama i
9d1dzla_



15.3 30 Fold:Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily:Group I dsDNA viruses
Family:Papovaviridae-like VP
10c1dzlA_



15.3 30 PDB header:virus
Chain: A: PDB Molecule:late major capsid protein l1;
PDBTitle: l1 protein of human papillomavirus 16
11c1u24A_



14.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:myo-inositol hexaphosphate phosphohydrolase;
PDBTitle: crystal structure of selenomonas ruminantium phytase
12c1vjqB_



13.8 27 PDB header:structural genomics, de novo protein
Chain: B: PDB Molecule:designed protein;
PDBTitle: designed protein based on backbone conformation of2 procarboxypeptidase-a (1aye) with sidechains chosen for maximal3 predicted stability.
13c2blcA_



12.1 57 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase;
PDBTitle: sp21 double mutant p. vivax dihydrofolate reductase in2 complex with des-chloropyrimethamine
14d2epsa1



11.0 22 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
15c3treA_



10.4 10 PDB header:translation
Chain: A: PDB Molecule:elongation factor p;
PDBTitle: structure of a translation elongation factor p (efp) from coxiella2 burnetii
16c2r5iL_



10.3 29 PDB header:viral protein
Chain: L: PDB Molecule:l1 protein;
PDBTitle: pentamer structure of major capsid protein l1 of human2 papilloma virus type 18
17d1j3ka_



10.1 57 Fold:Dihydrofolate reductase-like
Superfamily:Dihydrofolate reductase-like
Family:Dihydrofolate reductases
18c3dg8B_



10.1 57 PDB header:oxidoreductase, transferase
Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate
PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump
19c2kwzA_



9.8 33 PDB header:viral protein
Chain: A: PDB Molecule:protease ns2-3;
PDBTitle: solution structure of ns2 [60-99]
20c2kr6A_



9.7 29 PDB header:hydrolase
Chain: A: PDB Molecule:presenilin-1;
PDBTitle: solution structure of presenilin-1 ctf subunit
21c3oyyA_



not modelled 9.5 13 PDB header:translation
Chain: A: PDB Molecule:elongation factor p;
PDBTitle: structure of pseudomonas aeruginosa elongation factor p
22c2r5kE_



not modelled 9.3 30 PDB header:viral protein
Chain: E: PDB Molecule:major capsid protein l1;
PDBTitle: pentamer structure of major capsid protein l1 of human2 papilloma virus type 11
23c1q40C_



not modelled 8.2 44 PDB header:translation
Chain: C: PDB Molecule:mrna transport regulator mtr2;
PDBTitle: crystal structure of the c. albicans mtr2-mex67 m domain complex
24c2wl8D_



not modelled 8.1 27 PDB header:protein transport
Chain: D: PDB Molecule:peroxisomal biogenesis factor 19;
PDBTitle: x-ray crystal structure of pex19p
25c2voyB_



not modelled 8.1 32 PDB header:hydrolase
Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus
26c3iyjE_



not modelled 8.1 35 PDB header:virus
Chain: E: PDB Molecule:major capsid protein l1;
PDBTitle: bovine papillomavirus type 1 outer capsid
27c2y32C_



not modelled 7.9 25 PDB header:biotin-binding protein
Chain: C: PDB Molecule:blr5658 protein;
PDBTitle: crystal structure of bradavidin
28c2voyK_



not modelled 7.9 17 PDB header:hydrolase
Chain: K: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus
29d1oqdn_



not modelled 7.9 45 Fold:TNF receptor-like
Superfamily:TNF receptor-like
Family:BAFF receptor-like
30d1sg1x3



not modelled 7.6 30 Fold:TNF receptor-like
Superfamily:TNF receptor-like
Family:TNF receptor-like
31c2dlqA_



not modelled 7.6 22 PDB header:transcription
Chain: A: PDB Molecule:gli-kruppel family member hkr3;
PDBTitle: solution structure of the tandem four zf-c2h2 domain2 repeats of murine gli-kruppel family member hkr3
32d2ogqa2



not modelled 7.2 27 Fold:Polo-box domain
Superfamily:Polo-box domain
Family:Polo-box duplicated region
33d2dlqa3



not modelled 7.1 29 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
34c2y69Q_



not modelled 7.0 17 PDB header:electron transport
Chain: Q: PDB Molecule:cytochrome c oxidase subunit 4 isoform 1;
PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen
35c1etfB_



not modelled 6.6 13 PDB header:viral protein/rna
Chain: B: PDB Molecule:rev peptide;
PDBTitle: rev response element (rre) rna complexed with rev peptide,2 nmr, minimized average structure
36c1etgB_



not modelled 6.6 13 PDB header:viral protein/rna
Chain: B: PDB Molecule:rev peptide;
PDBTitle: rev response element (rre) rna complexed with rev peptide,2 nmr, 19 structures
37d2glia5



not modelled 6.5 86 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
38d2ogqa1



not modelled 6.3 20 Fold:Polo-box domain
Superfamily:Polo-box domain
Family:Polo-box duplicated region
39c3jsuA_



not modelled 6.2 57 PDB header:oxidoreductase, transferase
Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase;
PDBTitle: quadruple mutant(n51i+c59r+s108n+i164l) plasmodium falciparum2 dihydrofolate reductase-thymidylate synthase(pfdhfr-ts) complexed3 with qn254, nadph, and dump
40c1bkbA_



not modelled 6.2 15 PDB header:translation
Chain: A: PDB Molecule:translation initiation factor 5a;
PDBTitle: initiation factor 5a from archebacterium pyrobaculum2 aerophilum
41c3tdsC_



not modelled 6.1 27 PDB header:membrane protein
Chain: C: PDB Molecule:formate/nitrite transporter;
PDBTitle: crystal structure of hsc f194i
42d1v54d_



not modelled 6.0 17 Fold:Single transmembrane helix
Superfamily:Mitochondrial cytochrome c oxidase subunit IV
Family:Mitochondrial cytochrome c oxidase subunit IV
43c1wsoA_



not modelled 5.9 26 PDB header:neuropeptide
Chain: A: PDB Molecule:orexin-a;
PDBTitle: the solution structures of human orexin-a
44c3l60A_



not modelled 5.9 44 PDB header:oxidoreductase
Chain: A: PDB Molecule:branched-chain alpha-keto acid dehydrogenase;
PDBTitle: crystal structure of branched-chain alpha-keto acid2 dehydrogenase subunit e2 from mycobacterium tuberculosis
45c2kpaA_



not modelled 5.8 20 PDB header:hydrolase
Chain: A: PDB Molecule:arno(375-400);
PDBTitle: specific motifs of the v-atpase a2-subunit isoform interact2 with catalytic and regulatory domains of arno
46c2kpbA_



not modelled 5.8 20 PDB header:hydrolase
Chain: A: PDB Molecule:arno-p(375-400);
PDBTitle: specific motifs of the v-atpase a2-subunit isoform interact2 with catalytic and regulatory domains of arno
47c2eifA_



not modelled 5.8 10 PDB header:gene regulation
Chain: A: PDB Molecule:protein (eukaryotic translation initiation factor 5a);
PDBTitle: eukaryotic translation initiation factor 5a from methanococcus2 jannaschii
48d1dpba_



not modelled 5.5 44 Fold:CoA-dependent acyltransferases
Superfamily:CoA-dependent acyltransferases
Family:CAT-like
49d1b5sa_



not modelled 5.3 44 Fold:CoA-dependent acyltransferases
Superfamily:CoA-dependent acyltransferases
Family:CAT-like
50c2y69Z_



not modelled 5.2 17 PDB header:electron transport
Chain: Z: PDB Molecule:cytochrome c oxidase polypeptide 8h;
PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen
51c1dsjA_



not modelled 5.2 45 PDB header:viral peptide
Chain: A: PDB Molecule:vpr protein;
PDBTitle: nmr solution structure of vpr50_75, 20 structures
52c3b9yA_



not modelled 5.2 21 PDB header:transport protein
Chain: A: PDB Molecule:ammonium transporter family rh-like protein;
PDBTitle: crystal structure of the nitrosomonas europaea rh protein
53c2h2rB_



not modelled 5.1 22 PDB header:immune system
Chain: B: PDB Molecule:low affinity immunoglobulin epsilon fc receptor
PDBTitle: crystal structure of the human cd23 lectin domain, apo form

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite