Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA0JNW5
DateFri May 25 09:57:59 BST 2012
Unique Job ID542c8aca34e6f95b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3ojaB_
Top template information
PDB header:protein binding
Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein
PDBTitle: crystal structure of lrim1/apl1c complex
Confidence and coverage
Confidence: 97.0% Coverage: 10%
146 residues ( 10% of your sequence) have been modelled with 97.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
272 residues ( 19%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
Warning: 57% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINK
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  VFCNKASIRIPWTKLKTHPICLSLDKVIMEMSTCEEPRSPNGPSPIATASGQSEYGFAEK
Secondary structure 
SS confidence 
Disorder 
?????????????????????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  VVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNAHWEHGDLRFTRIQDPQRGEVLTF
Secondary structure 
SS confidence 
Disorder 
?????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  KEINWQMIRIEADATQSSHLEIMCAPVRLITNQSKIRVTLKRRLKDCNVIATKLVLILDD
Secondary structure 
SS confidence 
Disorder 
???????????????
?
?
????????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  LLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSMAPEPTQSSTVVASAQQVKTTQTSNAP
Secondary structure 
SS confidence 
Disorder 
?????????????????
??????????????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  DVNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHAKEKESNRRITGGAMQLSFTQLTI
Secondary structure 
SS confidence 
Disorder  ??????
???????????????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  DYYPYHKAGDSCNHWMYFSDATKTKNGWANELLHEFECNVEMLKQAVKDHNVGSPPKSPT
Secondary structure 
SS confidence 
Disorder 
?
??
???????????????????
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  HASPQHTQTEKDYPLKGTCRTPSVLSQQSKAKLMSSSVVVRLADFNIYQVSTAEQCRSSP
Secondary structure 
SS confidence 
Disorder  ???????????????????????????????????
?
??????????
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  KSMICCNKKSLYLPQEMSAVYIEFTEYYYPDGKDFPIPSPNLYSQLNALQFTVDERSILW
Secondary structure 
SS confidence 
Disorder 
?????????????
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  LNQFLLDLKQSLNQFMAVYKLNDNSKSDEHVDVRVDGLMLKFVIPSEVKSECHQDQPRAI
Secondary structure 
SS confidence 
Disorder 
??????????????
???
???????????
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  SIQSSEMIATNTRHCPNCRHSDLEALFQDFKDCDFFSKTYTSFPKSCDNFNLLHPIFQRH
Secondary structure 
SS confidence 
Disorder 
????
??????????
?
????
?????
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  AHEQDTKMHEIYKGNITPQLNKNTLKTSAATDVWAVYFSQFWIDYEGMKSGKGRPISFVD
Secondary structure 
SS confidence 
Disorder 
?????????????????????
?
???
????
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  SFPLSIWICQPTRYAESQKEPQTCNQVSLNTSQSESSDLAGRLKRKKLLKEYYSTESEPL
Secondary structure 
SS confidence 
Disorder 
??
?????????????????????????????????????????????????
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  TNGGQKPSSSDTFFRFSPSSSEADIHLLVHVHKHVSMQINHYQYLLLLFLHESLILLSEN
Secondary structure 
SS confidence 
Disorder  ????????????????????????
?
??
Disorder confidence 
 
   .........850.........860.........870.........880.........890.........900
Sequence  LRKDVEAVTGSPASQTSICIGILLRSAELALLLHPVDQANTLKSPVSESVSPVVPDYLPT
Secondary structure 
SS confidence 
Disorder 
???
??????????
???
???????????????????????????
Disorder confidence 
 
   .........910.........920.........930.........940.........950.........960
Sequence  ENGDFLSSKRKQISRDINRIRSVTVNHMSDNRSMSVDLSHIPLKDPLLFKSASDTNLQKG
Secondary structure 
SS confidence 
Disorder  ????????????????????????????????????????????????????????????
Disorder confidence 
 
   .........970.........980.........990.........1000.........1010.........1020
Sequence  ISFMDYLSDKHLGKISEDESSGLVYKSGSGEIGSETSDKKDSFYTDSSSILNYREDSNIL
Secondary structure 
SS confidence 
Disorder  ????????????????????????????????????????????????????????????
Disorder confidence 
 
   .........1030.........1040.........1050.........1060.........1070.........1080
Sequence  SFDSDGNQNILSSTLTSKGNETIESIFKAEDLLPEAASLSENLDISKEETPPVRTLKSQS
Secondary structure 
SS confidence 
Disorder  ??????????????????????????????????
?????????????????????????
Disorder confidence 
 
   .........1090.........1100.........1110.........1120.........1130.........1140
Sequence  SLSGKPKERCPPNLAPLCVSYKNMKRSSSQMSLDTISLDSMILEEQLLESDGSDSHMFLE
Secondary structure 
SS confidence 
Disorder  ??????????????????????????????????????????????????????
?
???
Disorder confidence 
 
   .........1150.........1160.........1170.........1180.........1190.........1200
Sequence  KGNKKNSTTNYRGTAESVNAGANLQNYGETSPDAISTNSEGAQENHDDLMSVVVFKITGV
Secondary structure 
SS confidence 
Disorder  ??????????????????????????????????????????????????????
????
Disorder confidence 
 
   .........1210.........1220.........1230.........1240.........1250.........1260
Sequence  NGEIDIRGEDTEICLQVNQVTPDQLGNISLRHYLCNRPVGSDQKAVIHSKSSPEISLRFE
Secondary structure 
SS confidence 
Disorder  ???????????
???
?
?
???????????????????????
??
Disorder confidence 
 
   .........1270.........1280.........1290.........1300.........1310.........1320
Sequence  SGPGAVIHSLLAEKNGFLQCHIENFSTEFLTSSLMNIQHFLEDETVATVMPMKIQVSNTK
Secondary structure 
SS confidence 
Disorder  ???????????????
?????
?
?
?
???
Disorder confidence 
 
   .........1330.........1340.........1350.........1360.........1370.........1380
Sequence  INLKDDSPRSSTVSLEPAPVTVHIDHLVVERSDDGSFHIRDSHMLNTGNDLKENVKSDSV
Secondary structure 
SS confidence 
Disorder 
?????
?
????????????????????
Disorder confidence 
 
   .........1390.........1400.........1410.........1420.........1430.........1440
Sequence  LLTSGKYDLKKQRSVTQATQTSPGVPWPSQSANFPEFSFDFTREQLMEENESLKQELAKA
Secondary structure 
SS confidence 
Disorder  ????????????????????????????????????????????????
Disorder confidence 
 
   .........1450.........1460....
Sequence  KMALAEAHLEKDALLHHIKKMTVE
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3oja chain B

3D model

Region: 1319 - 1464
Aligned: 146
Modelled: 146
Confidence: 97.0%
Identity: 10%
PDB header:protein binding
Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein
PDBTitle: crystal structure of lrim1/apl1c complex

Phyre2

PDB 3dtp chain A

3D model

Region: 1348 - 1464
Aligned: 117
Modelled: 117
Confidence: 94.3%
Identity: 8%
PDB header:contractile protein
Chain: A: PDB Molecule:myosin 2 heavy chain chimera of smooth and
PDBTitle: tarantula heavy meromyosin obtained by flexible docking to2 tarantula muscle thick filament cryo-em 3d-map

Phyre2

PDB 1ei3 chain C

3D model

Region: 1341 - 1464
Aligned: 124
Modelled: 124
Confidence: 92.4%
Identity: 7%
PDB header:
PDB COMPND:

Phyre2

PDB 1deq chain F

3D model

Region: 1354 - 1459
Aligned: 106
Modelled: 106
Confidence: 92.3%
Identity: 8%
PDB header:
PDB COMPND:

Phyre2

PDB 2d3e chain D

3D model

Region: 1340 - 1464
Aligned: 125
Modelled: 125
Confidence: 91.8%
Identity: 7%
PDB header:contractile protein
Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1
PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin

Phyre2

PDB 1deq chain O

3D model

Region: 1358 - 1464
Aligned: 107
Modelled: 107
Confidence: 91.5%
Identity: 9%
PDB header:
PDB COMPND:

Phyre2

PDB 2efr chain B

3D model

Region: 1312 - 1462
Aligned: 151
Modelled: 151
Confidence: 91.4%
Identity: 6%
PDB header:contractile protein
Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain;
PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution

Phyre2

PDB 1bf5 chain A

3D model

Region: 1309 - 1464
Aligned: 156
Modelled: 156
Confidence: 91.0%
Identity: 8%
PDB header:gene regulation/dna
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: tyrosine phosphorylated stat-1/dna complex

Phyre2

PDB 3u59 chain C

3D model

Region: 1365 - 1464
Aligned: 100
Modelled: 100
Confidence: 90.9%
Identity: 13%
PDB header:contractile protein
Chain: C: PDB Molecule:tropomyosin beta chain;
PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta

Phyre2

PDB 2fxm chain B

3D model

Region: 1356 - 1464
Aligned: 109
Modelled: 109
Confidence: 90.9%
Identity: 7%
PDB header:contractile protein
Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform;
PDBTitle: structure of the human beta-myosin s2 fragment

Phyre2

PDB 1yvl chain B

3D model

Region: 1193 - 1460
Aligned: 268
Modelled: 268
Confidence: 90.6%
Identity: 6%
PDB header:signaling protein
Chain: B: PDB Molecule:signal transducer and activator of transcription
PDBTitle: structure of unphosphorylated stat1

Phyre2

PDB 3hiz chain B

3D model

Region: 1341 - 1464
Aligned: 124
Modelled: 124
Confidence: 90.0%
Identity: 6%
PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha

Phyre2

PDB 3q8t chain B

3D model

Region: 1370 - 1462
Aligned: 93
Modelled: 93
Confidence: 89.4%
Identity: 9%
PDB header:apoptosis
Chain: B: PDB Molecule:beclin-1;
PDBTitle: crystal structure of the coiled coil domain of beclin 1, an essential2 autophagy protein

Phyre2

PDB 2b9c chain A

3D model

Region: 1333 - 1462
Aligned: 130
Modelled: 130
Confidence: 87.5%
Identity: 11%
PDB header:contractile protein
Chain: A: PDB Molecule:striated-muscle alpha tropomyosin;
PDBTitle: structure of tropomyosin's mid-region: bending and binding2 sites for actin

Phyre2

PDB 1y4c chain A

3D model

Region: 1319 - 1462
Aligned: 142
Modelled: 144
Confidence: 87.4%
Identity: 8%
PDB header:de novo protein
Chain: A: PDB Molecule:maltose binding protein fused with designed
PDBTitle: designed helical protein fusion mbp

Phyre2

PDB 3ghg chain K

3D model

Region: 1351 - 1462
Aligned: 110
Modelled: 112
Confidence: 87.4%
Identity: 5%
PDB header:blood clotting
Chain: K: PDB Molecule:fibrinogen beta chain;
PDBTitle: crystal structure of human fibrinogen

Phyre2

PDB 1ei3 chain E

3D model

Region: 1351 - 1464
Aligned: 112
Modelled: 114
Confidence: 87.1%
Identity: 8%
PDB header:
PDB COMPND:

Phyre2

PDB 1ev0 chain A

3D model

Region: 5 - 42
Aligned: 37
Modelled: 38
Confidence: 86.4%
Identity: 22%
Fold: Cell division protein MinE topological specificity domain
Superfamily: Cell division protein MinE topological specificity domain
Family: Cell division protein MinE topological specificity domain

Phyre2

PDB 1c1g chain A

3D model

Region: 1196 - 1464
Aligned: 268
Modelled: 269
Confidence: 82.7%
Identity: 6%
PDB header:contractile protein
Chain: A: PDB Molecule:tropomyosin;
PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form

Phyre2

PDB 3cwg chain A

3D model

Region: 1337 - 1464
Aligned: 128
Modelled: 128
Confidence: 81.9%
Identity: 9%
PDB header:transcription
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: unphosphorylated mouse stat3 core fragment

Phyre2

PDB 1ete chain A

3D model

Region: 638 - 704
Aligned: 58
Modelled: 58
Confidence: 52.0%
Identity: 19%
Fold: 4-helical cytokines
Superfamily: 4-helical cytokines
Family: Short-chain cytokines

Phyre2
1
c3ojaB_
2
c3dtpA_
3
c1ei3C_
4
c1deqF_
5
c2d3eD_
6
c1deqO_
7
c2efrB_
8
c1bf5A_
9
c3u59C_
10
c2fxmB_
11
c1yvlB_
12
c3hizB_
13
c3q8tB_
14
c2b9cA_
15
c1y4cA_
16
c3ghgK_
17
c1ei3E_
18
d1ev0a_
19
c1c1gA_
20
c3cwgA_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
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40
41
d1etea_
42
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44
45
46
47
48
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54
55
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170



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3ojaB_
97.0 10 PDB header:protein binding
Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein
PDBTitle: crystal structure of lrim1/apl1c complex
2c3dtpA_
94.3 8 PDB header:contractile protein
Chain: A: PDB Molecule:myosin 2 heavy chain chimera of smooth and
PDBTitle: tarantula heavy meromyosin obtained by flexible docking to2 tarantula muscle thick filament cryo-em 3d-map
3c1ei3C_
92.4 7 PDB header:
PDB COMPND:
4c1deqF_
92.3 8 PDB header:
PDB COMPND:
5c2d3eD_
91.8 7 PDB header:contractile protein
Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1
PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin
6c1deqO_
91.5 9 PDB header:
PDB COMPND:
7c2efrB_
91.4 6 PDB header:contractile protein
Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain;
PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution
8c1bf5A_
91.0 8 PDB header:gene regulation/dna
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: tyrosine phosphorylated stat-1/dna complex
9c3u59C_
90.9 13 PDB header:contractile protein
Chain: C: PDB Molecule:tropomyosin beta chain;
PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta
10c2fxmB_
90.9 7 PDB header:contractile protein
Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform;
PDBTitle: structure of the human beta-myosin s2 fragment
11c1yvlB_
90.6 6 PDB header:signaling protein
Chain: B: PDB Molecule:signal transducer and activator of transcription
PDBTitle: structure of unphosphorylated stat1
12c3hizB_
90.0 6 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
13c3q8tB_
89.4 9 PDB header:apoptosis
Chain: B: PDB Molecule:beclin-1;
PDBTitle: crystal structure of the coiled coil domain of beclin 1, an essential2 autophagy protein
14c2b9cA_
87.5 11 PDB header:contractile protein
Chain: A: PDB Molecule:striated-muscle alpha tropomyosin;
PDBTitle: structure of tropomyosin's mid-region: bending and binding2 sites for actin
15c1y4cA_
87.4 8 PDB header:de novo protein
Chain: A: PDB Molecule:maltose binding protein fused with designed
PDBTitle: designed helical protein fusion mbp
16c3ghgK_
87.4 5 PDB header:blood clotting
Chain: K: PDB Molecule:fibrinogen beta chain;
PDBTitle: crystal structure of human fibrinogen
17c1ei3E_
87.1 8 PDB header:
PDB COMPND:
18d1ev0a_
86.4 22 Fold:Cell division protein MinE topological specificity domain
Superfamily:Cell division protein MinE topological specificity domain
Family:Cell division protein MinE topological specificity domain
19c1c1gA_
82.7 6 PDB header:contractile protein
Chain: A: PDB Molecule:tropomyosin;
PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form
20c3cwgA_
81.9 9 PDB header:transcription
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: unphosphorylated mouse stat3 core fragment
21c1jchC_
not modelled 80.1 9 PDB header:ribosome inhibitor, hydrolase
Chain: C: PDB Molecule:colicin e3;
PDBTitle: crystal structure of colicin e3 in complex with its immunity protein
22c3hnwB_
not modelled 77.1 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a basic coiled-coil protein of unknown function2 from eubacterium eligens atcc 27750
23c3vkgB_
not modelled 75.3 8 PDB header:motor protein
Chain: B: PDB Molecule:dynein heavy chain, cytoplasmic;
PDBTitle: crystal structure of an motor protein
24c3ol1A_
not modelled 74.8 9 PDB header:structural protein
Chain: A: PDB Molecule:vimentin;
PDBTitle: crystal structure of vimentin (fragment 144-251) from homo sapiens,2 northeast structural genomics consortium target hr4796b
25c2i1jA_
not modelled 73.3 11 PDB header:cell adhesion, membrane protein
Chain: A: PDB Molecule:moesin;
PDBTitle: moesin from spodoptera frugiperda at 2.1 angstroms resolution
26c2y3aB_
not modelled 70.5 9 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
27c3ojaA_
not modelled 68.0 6 PDB header:protein binding
Chain: A: PDB Molecule:leucine-rich immune molecule 1;
PDBTitle: crystal structure of lrim1/apl1c complex
28c1bg1A_
not modelled 67.4 9 PDB header:transcription/dna
Chain: A: PDB Molecule:protein (transcription factor stat3b);
PDBTitle: transcription factor stat3b/dna complex
29c2jeeA_
not modelled 64.1 22 PDB header:cell cycle
Chain: A: PDB Molecule:yiiu;
PDBTitle: xray structure of e. coli yiiu
30c3o0zD_
not modelled 63.5 12 PDB header:transferase
Chain: D: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of a coiled-coil domain from human rock i
31c4a55B_
not modelled 62.4 7 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha;
PDBTitle: crystal structure of p110alpha in complex with ish2 of p85alpha and2 the inhibitor pik-108
32c2kxoA_
not modelled 60.8 31 PDB header:cell cycle
Chain: A: PDB Molecule:cell division topological specificity factor;
PDBTitle: solution nmr structure of the cell division regulator mine protein2 from neisseria gonorrhoeae
33c1g8xB_
not modelled 60.3 6 PDB header:structural protein
Chain: B: PDB Molecule:myosin ii heavy chain fused to alpha-actinin 3;
PDBTitle: structure of a genetically engineered molecular motor
34c1wt6B_
not modelled 59.9 12 PDB header:transferase
Chain: B: PDB Molecule:myotonin-protein kinase;
PDBTitle: coiled-coil domain of dmpk
35c2gl2B_
not modelled 59.4 7 PDB header:cell adhesion
Chain: B: PDB Molecule:adhesion a;
PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada
36c2zvnF_
not modelled 57.8 12 PDB header:signaling protein/transcription
Chain: F: PDB Molecule:nf-kappa-b essential modulator;
PDBTitle: nemo cozi domain incomplex with diubiquitin in p2121212 space group
37c3n4xB_
not modelled 55.5 19 PDB header:replication
Chain: B: PDB Molecule:monopolin complex subunit csm1;
PDBTitle: structure of csm1 full-length
38c3ipkA_
not modelled 55.2 7 PDB header:cell adhesion
Chain: A: PDB Molecule:agi/ii;
PDBTitle: crystal structure of a3vp1 of agi/ii of streptococcus mutans
39c3r9jD_
not modelled 54.8 22 PDB header:cell cycle,hydrolase/cell cycle
Chain: D: PDB Molecule:cell division topological specificity factor;
PDBTitle: 4.3a resolution structure of a mind-mine(i24n) protein complex
40c2v4hA_
not modelled 54.7 12 PDB header:transcription
Chain: A: PDB Molecule:nf-kappa-b essential modulator;
PDBTitle: nemo cc2-lz domain - 1d5 darpin complex
41d1etea_
52.0 19 Fold:4-helical cytokines
Superfamily:4-helical cytokines
Family:Short-chain cytokines
42c3qh9A_
not modelled 48.3 13 PDB header:structural protein
Chain: A: PDB Molecule:liprin-beta-2;
PDBTitle: human liprin-beta2 coiled-coil
43c3vkhD_
not modelled 45.5 10 PDB header:motor protein
Chain: D: PDB Molecule:dynein heavy chain, cytoplasmic;
PDBTitle: crystal structure of an motor protein
44d1gsma2
not modelled 45.0 23 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Immunoglobulin
Family:I set domains
45c3a7pB_
not modelled 44.4 10 PDB header:protein transport
Chain: B: PDB Molecule:autophagy protein 16;
PDBTitle: the crystal structure of saccharomyces cerevisiae atg16
46c2rd0B_
not modelled 44.0 6 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha;
PDBTitle: structure of a human p110alpha/p85alpha complex
47c1ciiA_
not modelled 42.5 13 PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
48c1l8dB_
not modelled 41.9 10 PDB header:replication
Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: rad50 coiled-coil zn hook
49c2w6aB_
not modelled 41.2 24 PDB header:signaling protein
Chain: B: PDB Molecule:arf gtpase-activating protein git1;
PDBTitle: x-ray structure of the dimeric git1 coiled-coil domain
50c1debA_
not modelled 40.8 24 PDB header:structural protein
Chain: A: PDB Molecule:adenomatous polyposis coli protein;
PDBTitle: crystal structure of the n-terminal coiled coil domain from2 apc
51c2oevA_
not modelled 39.9 5 PDB header:protein transport
Chain: A: PDB Molecule:programmed cell death 6-interacting protein;
PDBTitle: crystal structure of alix/aip1
52c2eqbC_
not modelled 36.9 17 PDB header:endocytosis/exocytosis
Chain: C: PDB Molecule:rab guanine nucleotide exchange factor sec2;
PDBTitle: crystal structure of the rab gtpase sec4p, the sec2p gef2 domain, and phosphate complex
53d1pugb_
not modelled 35.4 28 Fold:YbaB-like
Superfamily:YbaB-like
Family:YbaB-like
54d1hn6a_
not modelled 34.9 11 Fold:Apical membrane antigen 1
Superfamily:Apical membrane antigen 1
Family:Apical membrane antigen 1
55c1deqD_
not modelled 34.6 9 PDB header:
PDB COMPND:
56c1ybxA_
not modelled 33.3 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein;
PDBTitle: conserved hypothetical protein cth-383 from clostridium thermocellum
57d1tlta2
not modelled 32.2 13 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Glucose 6-phosphate dehydrogenase-like
58d1xeaa2
not modelled 32.0 6 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Glucose 6-phosphate dehydrogenase-like
59c2v1yB_
not modelled 31.8 6 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha;
PDBTitle: structure of a phosphoinositide 3-kinase alpha adaptor-2 binding domain (abd) in a complex with the ish2 domain3 from p85 alpha
60c2x7aB_
not modelled 31.7 21 PDB header:immune system
Chain: B: PDB Molecule:bone marrow stromal antigen 2;
PDBTitle: structural basis of hiv-1 tethering to membranes by the2 bst2-tetherin ectodomain
61d1mvha_
not modelled 31.6 27 Fold:beta-clip
Superfamily:SET domain
Family:Histone lysine methyltransferases
62c1mvhA_
not modelled 31.6 27 PDB header:transferase
Chain: A: PDB Molecule:cryptic loci regulator 4;
PDBTitle: structure of the set domain histone lysine2 methyltransferase clr4
63d1kb0a1
not modelled 30.8 13 Fold:Cytochrome c
Superfamily:Cytochrome c
Family:Quinoprotein alcohol dehydrogenase, C-terminal domain
64c3c9jD_
not modelled 30.7 35 PDB header:membrane protein
Chain: D: PDB Molecule:proton channel protein m2, transmembrane segment;
PDBTitle: the crystal structure of transmembrane domain of m2 protein and2 amantadine complex
65d1pvga1
not modelled 30.7 33 Fold:Ribosomal protein S5 domain 2-like
Superfamily:Ribosomal protein S5 domain 2-like
Family:DNA gyrase/MutL, second domain
66c3c9jC_
not modelled 30.6 35 PDB header:membrane protein
Chain: C: PDB Molecule:proton channel protein m2, transmembrane segment;
PDBTitle: the crystal structure of transmembrane domain of m2 protein and2 amantadine complex
67c2rlfA_
not modelled 29.6 26 PDB header:proton transport
Chain: A: PDB Molecule:matrix protein 2;
PDBTitle: proton channel m2 from influenza a in complex with2 inhibitor rimantadine
68c2v71A_
not modelled 29.1 7 PDB header:nuclear protein
Chain: A: PDB Molecule:nuclear distribution protein nude-like 1;
PDBTitle: coiled-coil region of nudel
69c3vkhB_
not modelled 29.0 5 PDB header:motor protein
Chain: B: PDB Molecule:dynein heavy chain, cytoplasmic;
PDBTitle: crystal structure of an motor protein
70c3o0rC_
not modelled 27.8 19 PDB header:immune system/oxidoreductase
Chain: C: PDB Molecule:nitric oxide reductase subunit c;
PDBTitle: crystal structure of nitric oxide reductase from pseudomonas2 aeruginosa in complex with antibody fragment
71c3ddyA_
not modelled 27.8 27 PDB header:luminescent protein
Chain: A: PDB Molecule:lumazine protein;
PDBTitle: structure of lumazine protein, an optical transponder of luminescent2 bacteria
72c2wpqA_
not modelled 27.2 4 PDB header:membrane protein
Chain: A: PDB Molecule:trimeric autotransporter adhesin fragment;
PDBTitle: salmonella enterica sada 479-519 fused to gcn4 adaptors (2 sadak3, in-register fusion)
73c3m9hB_
not modelled 27.2 21 PDB header:chaperone
Chain: B: PDB Molecule:proteasome-associated atpase;
PDBTitle: crystal structure of the amino terminal coiled coil domain of the2 mycobacterium tuberculosis proteasomal atpase mpa
74d1ccra_
not modelled 27.2 16 Fold:Cytochrome c
Superfamily:Cytochrome c
Family:monodomain cytochrome c
75c2xzrA_
not modelled 27.1 8 PDB header:cell adhesion
Chain: A: PDB Molecule:immunoglobulin-binding protein eibd;
PDBTitle: escherichia coli immunoglobulin-binding protein eibd 391-438 fused2 to gcn4 adaptors
76c3f42A_
not modelled 27.0 39 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:protein hp0035;
PDBTitle: crystal structure of uncharacterized protein hp0035 from helicobacter2 pylori
77d2rspa_
not modelled 26.9 19 Fold:Acid proteases
Superfamily:Acid proteases
Family:Retroviral protease (retropepsin)
78d1an2a_
not modelled 26.8 6 Fold:HLH-like
Superfamily:HLH, helix-loop-helix DNA-binding domain
Family:HLH, helix-loop-helix DNA-binding domain
79d1puga_
not modelled 26.7 26 Fold:YbaB-like
Superfamily:YbaB-like
Family:YbaB-like
80d1j8ba_
not modelled 26.5 15 Fold:YbaB-like
Superfamily:YbaB-like
Family:YbaB-like
81c3c9jB_
not modelled 26.5 35 PDB header:membrane protein
Chain: B: PDB Molecule:proton channel protein m2, transmembrane segment;
PDBTitle: the crystal structure of transmembrane domain of m2 protein and2 amantadine complex
82d2cs3a1
not modelled 26.2 33 Fold:RING/U-box
Superfamily:RING/U-box
Family:Variant RING domain
83c4e61A_
not modelled 26.0 12 PDB header:cell cycle
Chain: A: PDB Molecule:protein bim1;
PDBTitle: crystal structure of the eb1-like motif of bim1p
84d2au5a1
not modelled 26.0 18 Fold:EF2947-like
Superfamily:EF2947-like
Family:EF2947-like
85c3a35B_
not modelled 26.0 33 PDB header:luminescent protein
Chain: B: PDB Molecule:lumazine protein;
PDBTitle: crystal structure of lump complexed with riboflavin
86d2b9ea1
not modelled 25.9 33 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
87c3na7A_
not modelled 25.8 12 PDB header:gene regulation, chaperone
Chain: A: PDB Molecule:hp0958;
PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874
88d1ynra1
not modelled 25.8 28 Fold:Cytochrome c
Superfamily:Cytochrome c
Family:monodomain cytochrome c
89c3mkxC_
not modelled 25.8 11 PDB header:antiviral protein
Chain: C: PDB Molecule:bone marrow stromal antigen 2;
PDBTitle: crystal structure of bst2/tetherin
90c3pbpL_
not modelled 25.7 45 PDB header:transport protein,structural protein
Chain: L: PDB Molecule:nucleoporin nup159;
PDBTitle: structure of the yeast heterotrimeric nup82-nup159-nup116 nucleoporin2 complex
91c2r3aA_
not modelled 25.6 25 PDB header:transferase
Chain: A: PDB Molecule:histone-lysine n-methyltransferase suv39h2;
PDBTitle: methyltransferase domain of human suppressor of variegation2 3-9 homolog 2
92c2zzsW_
not modelled 25.6 25 PDB header:electron transport
Chain: W: PDB Molecule:
PDBTitle: crystal structure of cytochrome c554 from vibrio2 parahaemolyticus strain rimd2210633
93c3idwA_
not modelled 25.6 18 PDB header:endocytosis
Chain: A: PDB Molecule:actin cytoskeleton-regulatory complex protein sla1;
PDBTitle: crystal structure of sla1 homology domain 2
94c2no2A_
not modelled 25.4 9 PDB header:cell adhesion
Chain: A: PDB Molecule:huntingtin-interacting protein 1;
PDBTitle: crystal structure of the dllrkn-containing coiled-coil2 domain of huntingtin-interacting protein 1
95c2v66C_
not modelled 25.4 10 PDB header:structural protein
Chain: C: PDB Molecule:nuclear distribution protein nude-like 1;
PDBTitle: crystal structure of the coiled-coil domain of ndel1 (a.a.2 58 to 169)c
96c3c9jA_
not modelled 25.2 35 PDB header:membrane protein
Chain: A: PDB Molecule:proton channel protein m2, transmembrane segment;
PDBTitle: the crystal structure of transmembrane domain of m2 protein and2 amantadine complex
97c2rd0A_
not modelled 25.1 11 PDB header:transferase/oncoprotein
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: structure of a human p110alpha/p85alpha complex
98c2wvrB_
not modelled 25.1 17 PDB header:replication
Chain: B: PDB Molecule:geminin;
PDBTitle: human cdt1:geminin complex
99c3oa7A_
not modelled 25.1 11 PDB header:structural protein
Chain: A: PDB Molecule:head morphogenesis protein, chaotic nuclear migration
PDBTitle: structure of the c-terminal domain of cnm67, a core component of the2 spindle pole body of saccharomyces cerevisiae
100c1ci6A_
not modelled 25.0 17 PDB header:transcription
Chain: A: PDB Molecule:transcription factor atf-4;
PDBTitle: transcription factor atf4-c/ebp beta bzip heterodimer
101c3u1aC_
not modelled 24.9 11 PDB header:contractile protein
Chain: C: PDB Molecule:smooth muscle tropomyosin alpha;
PDBTitle: n-terminal 81-aa fragment of smooth muscle tropomyosin alpha
102c2wxoA_
not modelled 24.8 13 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: the crystal structure of the murine class ia pi 3-kinase2 p110delta in complex with as5.
103c1kzlA_
not modelled 24.6 18 PDB header:transferase
Chain: A: PDB Molecule:riboflavin synthase;
PDBTitle: riboflavin synthase from s.pombe bound to2 carboxyethyllumazine
104d1e6ya1
not modelled 24.6 13 Fold:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
Superfamily:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
Family:Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
105d1m70a2
not modelled 24.6 25 Fold:Cytochrome c
Superfamily:Cytochrome c
Family:Two-domain cytochrome c
106c3kltB_
not modelled 23.9 16 PDB header:structural protein
Chain: B: PDB Molecule:vimentin;
PDBTitle: crystal structure of a vimentin fragment
107c1i8dB_
not modelled 23.9 36 PDB header:transferase
Chain: B: PDB Molecule:riboflavin synthase;
PDBTitle: crystal structure of riboflavin synthase
108c3h6lA_
not modelled 23.7 28 PDB header:transferase
Chain: A: PDB Molecule:histone-lysine n-methyltransferase setd2;
PDBTitle: methyltransferase domain of human set domain-containing protein 2
109c3bnwA_
not modelled 23.6 18 PDB header:transferase
Chain: A: PDB Molecule:riboflavin kinase, putative;
PDBTitle: crystal structure of riboflavin kinase from trypanosoma brucei
110d1mjsa_
not modelled 23.5 30 Fold:SMAD/FHA domain
Superfamily:SMAD/FHA domain
Family:SMAD domain
111c1gd2G_
not modelled 23.4 8 PDB header:transcription/dna
Chain: G: PDB Molecule:transcription factor pap1;
PDBTitle: crystal structure of bzip transcription factor pap1 bound2 to dna
112c3q0xA_
not modelled 23.4 15 PDB header:structural protein
Chain: A: PDB Molecule:centriole protein;
PDBTitle: n-terminal coiled-coil dimer domain of c. reinhardtii sas-6 homolog2 bld12p
113c2gk4A_
not modelled 23.4 35 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein;
PDBTitle: the crystal structure of the dna/pantothenate metabolism flavoprotein2 from streptococcus pneumoniae
114d1cc5a_
not modelled 23.2 31 Fold:Cytochrome c
Superfamily:Cytochrome c
Family:monodomain cytochrome c
115c2y3aA_
not modelled 23.0 15 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
116c2kqtD_
not modelled 23.0 33 PDB header:transport protein
Chain: D: PDB Molecule:m2 protein;
PDBTitle: solid-state nmr structure of the m2 transmembrane peptide of the2 influenza a virus in dmpc lipid bilayers bound to deuterated3 amantadine
117c2kqtB_
not modelled 23.0 33 PDB header:transport protein
Chain: B: PDB Molecule:m2 protein;
PDBTitle: solid-state nmr structure of the m2 transmembrane peptide of the2 influenza a virus in dmpc lipid bilayers bound to deuterated3 amantadine
118c2kqtA_
not modelled 23.0 33 PDB header:transport protein
Chain: A: PDB Molecule:m2 protein;
PDBTitle: solid-state nmr structure of the m2 transmembrane peptide of the2 influenza a virus in dmpc lipid bilayers bound to deuterated3 amantadine
119c2kqtC_
not modelled 23.0 33 PDB header:transport protein
Chain: C: PDB Molecule:m2 protein;
PDBTitle: solid-state nmr structure of the m2 transmembrane peptide of the2 influenza a virus in dmpc lipid bilayers bound to deuterated3 amantadine
120c2wt7B_
not modelled 22.9 12 PDB header:transcription
Chain: B: PDB Molecule:transcription factor mafb;
PDBTitle: crystal structure of the bzip heterodimeric complex2 mafb:cfos bound to dna

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