Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA0JLT2
DateTue Apr 3 15:10:21 BST 2012
Unique Job IDd2d26d79caee891d

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2gqba1
Top template information
Fold:RPA2825-like
Superfamily:RPA2825-like
Family:RPA2825-like
Confidence and coverage
Confidence: 23.3% Coverage: 18%
43 residues ( 18% of your sequence) have been modelled with 23.3% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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Warning: 65% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MENFTALFGAQADPPPPPTALGFGPGKPPPPPPPPAGGGPGTAPPPTAATAPPGADKSGA
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Disorder  ???????


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?
?????????????????????????????????????
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   .........70.........80.........90.........100.........110.........120
Sequence  GCGPFYLMRELPGSTELTGSTNLITHYNLEQAYNKFCGKKVKEKLSNFLPDLPGMIDLPG
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??????????















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???
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   .........130.........140.........150.........160.........170.........180
Sequence  SHDNSSLRSLIEKPPILSSSFNPITGTMLAGFRLHTGPLPEQCRLMHIQPPKKKNKHKHK
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Disorder  ??????????
???????????????????

?













?????????????
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   .........190.........200.........210.........220.........230.........240
Sequence  QSRTQDPVPPETPSDSDHKKKKKKKEEDPDRKRKKKEKKKKKNRHSPDHPGMGSSQASSS
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Disorder  ??????????????????????????????











??????????????????
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   ....
Sequence  SSLR
Secondary structure 



SS confidence 



Disorder  ????
Disorder confidence 



 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2gqb chain A domain 1

3D model

Region: 6 - 57
Aligned: 43
Modelled: 52
Confidence: 23.3%
Identity: 47%
Fold: RPA2825-like
Superfamily: RPA2825-like
Family: RPA2825-like

Phyre2

PDB 2grg chain A domain 1

3D model

Region: 104 - 154
Aligned: 49
Modelled: 51
Confidence: 15.8%
Identity: 24%
Fold: Profilin-like
Superfamily: YNR034W-A-like
Family: YNR034W-A-like

Phyre2

PDB 3kys chain C

3D model

Region: 76 - 103
Aligned: 28
Modelled: 28
Confidence: 9.4%
Identity: 32%
PDB header:transcription/protein binding
Chain: C: PDB Molecule:transcriptional enhancer factor tef-1;
PDBTitle: crystal structure of human yap and tead complex

Phyre2

PDB 3dbo chain A

3D model

Region: 2 - 14
Aligned: 13
Modelled: 13
Confidence: 9.3%
Identity: 62%
PDB header:toxin/antitoxin
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a member of the vapbc family of toxin-antitoxin2 systems, vapbc-5, from mycobacterium tuberculosis

Phyre2

PDB 1dxs chain A

3D model

Region: 158 - 164
Aligned: 7
Modelled: 7
Confidence: 9.1%
Identity: 57%
Fold: SAM domain-like
Superfamily: SAM/Pointed domain
Family: SAM (sterile alpha motif) domain

Phyre2

PDB 3q87 chain A

3D model

Region: 89 - 111
Aligned: 23
Modelled: 23
Confidence: 7.8%
Identity: 26%
PDB header:transferase activator/transferase
Chain: A: PDB Molecule:putative uncharacterized protein ecu08_1170;
PDBTitle: structure of eukaryotic translation termination complex2 methyltransferase mtq2-trm112

Phyre2

PDB 1kcf chain A domain 1

3D model

Region: 107 - 134
Aligned: 28
Modelled: 28
Confidence: 7.5%
Identity: 25%
Fold: LEM/SAP HeH motif
Superfamily: SAP domain
Family: SAP domain

Phyre2

PDB 3gn6 chain B

3D model

Region: 48 - 69
Aligned: 22
Modelled: 22
Confidence: 7.2%
Identity: 45%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:ct0912, orfan protein with a ferredoxin-like domain repeat;
PDBTitle: crystal structure of ct0912, orfan protein from chlorobium tepidum2 with a ferredoxin-like domain repeat (np_661805.1) from chlorobium3 tepidum tls at 1.80 a resolution

Phyre2

PDB 1k4z chain A

3D model

Region: 158 - 165
Aligned: 8
Modelled: 8
Confidence: 7.2%
Identity: 50%
Fold: Single-stranded right-handed beta-helix
Superfamily: C-terminal domain of adenylylcyclase associated protein
Family: C-terminal domain of adenylylcyclase associated protein

Phyre2

PDB 2eqo chain A

3D model

Region: 126 - 142
Aligned: 17
Modelled: 17
Confidence: 7.1%
Identity: 24%
PDB header:transcription
Chain: A: PDB Molecule:tnf receptor-associated factor 3-interacting
PDBTitle: solution structure of the stn_traf3ip1_nd domain of2 interleukin 13 receptor alpha 1-binding protein-1 [homo3 sapiens]

Phyre2

PDB 2h4o chain A domain 1

3D model

Region: 87 - 102
Aligned: 16
Modelled: 16
Confidence: 6.2%
Identity: 31%
Fold: YonK-like
Superfamily: YonK-like
Family: Yonk-like

Phyre2

PDB 2pw6 chain A domain 1

3D model

Region: 64 - 101
Aligned: 38
Modelled: 38
Confidence: 5.8%
Identity: 8%
Fold: Phosphorylase/hydrolase-like
Superfamily: LigB-like
Family: LigB-like

Phyre2

PDB 1k8f chain A

3D model

Region: 158 - 165
Aligned: 8
Modelled: 8
Confidence: 5.8%
Identity: 50%
Fold: Single-stranded right-handed beta-helix
Superfamily: C-terminal domain of adenylylcyclase associated protein
Family: C-terminal domain of adenylylcyclase associated protein

Phyre2

PDB 2b0r chain B

3D model

Region: 158 - 165
Aligned: 8
Modelled: 8
Confidence: 5.7%
Identity: 38%
PDB header:unknown function
Chain: B: PDB Molecule:possible adenyl cyclase-associated protein;
PDBTitle: crystal structure of cyclase-associated protein from2 cryptosporidium parvum

Phyre2

PDB 2j9w chain B

3D model

Region: 68 - 97
Aligned: 30
Modelled: 30
Confidence: 5.4%
Identity: 33%
PDB header:protein transport
Chain: B: PDB Molecule:vps28-prov protein;
PDBTitle: structural insight into the escrt-i-ii link and its role in2 mvb trafficking

Phyre2

PDB 1gzs chain B

3D model

Region: 49 - 66
Aligned: 18
Modelled: 18
Confidence: 5.2%
Identity: 50%
Fold: SopE-like GEF domain
Superfamily: SopE-like GEF domain
Family: SopE-like GEF domain

Phyre2
1

d2gqba1
2

d2grga1
3

c3kysC_
4

c3dboA_
5

d1dxsa_
6

c3q87A_
7

d1kcfa1
8

c3gn6B_
9

d1k4za_
10

c2eqoA_
11

d2h4oa1
12

d2pw6a1
13

d1k8fa_
14

c2b0rB_
15

c2j9wB_
16

d1gzsb_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2gqba1



23.3 47 Fold:RPA2825-like
Superfamily:RPA2825-like
Family:RPA2825-like
2d2grga1



15.8 24 Fold:Profilin-like
Superfamily:YNR034W-A-like
Family:YNR034W-A-like
3c3kysC_



9.4 32 PDB header:transcription/protein binding
Chain: C: PDB Molecule:transcriptional enhancer factor tef-1;
PDBTitle: crystal structure of human yap and tead complex
4c3dboA_



9.3 62 PDB header:toxin/antitoxin
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a member of the vapbc family of toxin-antitoxin2 systems, vapbc-5, from mycobacterium tuberculosis
5d1dxsa_



9.1 57 Fold:SAM domain-like
Superfamily:SAM/Pointed domain
Family:SAM (sterile alpha motif) domain
6c3q87A_



7.8 26 PDB header:transferase activator/transferase
Chain: A: PDB Molecule:putative uncharacterized protein ecu08_1170;
PDBTitle: structure of eukaryotic translation termination complex2 methyltransferase mtq2-trm112
7d1kcfa1



7.5 25 Fold:LEM/SAP HeH motif
Superfamily:SAP domain
Family:SAP domain
8c3gn6B_



7.2 45 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:ct0912, orfan protein with a ferredoxin-like domain repeat;
PDBTitle: crystal structure of ct0912, orfan protein from chlorobium tepidum2 with a ferredoxin-like domain repeat (np_661805.1) from chlorobium3 tepidum tls at 1.80 a resolution
9d1k4za_



7.2 50 Fold:Single-stranded right-handed beta-helix
Superfamily:C-terminal domain of adenylylcyclase associated protein
Family:C-terminal domain of adenylylcyclase associated protein
10c2eqoA_



7.1 24 PDB header:transcription
Chain: A: PDB Molecule:tnf receptor-associated factor 3-interacting
PDBTitle: solution structure of the stn_traf3ip1_nd domain of2 interleukin 13 receptor alpha 1-binding protein-1 [homo3 sapiens]
11d2h4oa1



6.2 31 Fold:YonK-like
Superfamily:YonK-like
Family:Yonk-like
12d2pw6a1



5.8 8 Fold:Phosphorylase/hydrolase-like
Superfamily:LigB-like
Family:LigB-like
13d1k8fa_



5.8 50 Fold:Single-stranded right-handed beta-helix
Superfamily:C-terminal domain of adenylylcyclase associated protein
Family:C-terminal domain of adenylylcyclase associated protein
14c2b0rB_



5.7 38 PDB header:unknown function
Chain: B: PDB Molecule:possible adenyl cyclase-associated protein;
PDBTitle: crystal structure of cyclase-associated protein from2 cryptosporidium parvum
15c2j9wB_



5.4 33 PDB header:protein transport
Chain: B: PDB Molecule:vps28-prov protein;
PDBTitle: structural insight into the escrt-i-ii link and its role in2 mvb trafficking
16d1gzsb_



5.2 50 Fold:SopE-like GEF domain
Superfamily:SopE-like GEF domain
Family:SopE-like GEF domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite