Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA0AVI2
DateWed May 9 17:44:31 BST 2012
Unique Job ID74f8e09f1a43eb2a

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1dqvA_
Top template information
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:synaptotagmin iii;
PDBTitle: crystal structure of synaptotagmin iii c2a/c2b
Confidence and coverage
Confidence: 99.9% Coverage: 11%
226 residues ( 11% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
674 residues ( 32%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLRLVVQSAKIDPPLAPLPRPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLEND
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   .........70.........80.........90.........100.........110.........120
Sequence  SFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQV
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   .........130.........140.........150.........160.........170.........180
Sequence  AHMSNQDIEKTGAEDHLGITAREAASQKLMVPGSTAHRALSSKPQHFQVRVKVFEARQLM
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   .........190.........200.........210.........220.........230.........240
Sequence  GNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILIQTDIGFIYH
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   .........250.........260.........270.........280.........290.........300
Sequence  SPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQKLLYGTDDTDIQIFKS
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   .........310.........320.........330.........340.........350.........360
Sequence  AVVPINMAYLQLFIYCAEDLHLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILTF
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   .........370.........380.........390.........400.........410.........420
Sequence  RIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRVY
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   .........430.........440.........450.........460.........470.........480
Sequence  SGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDST
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   .........490.........500.........510.........520.........530.........540
Sequence  IKDLSHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKPLV
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   .........550.........560.........570.........580.........590.........600
Sequence  SSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDTL
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   .........610.........620.........630.........640.........650.........660
Sequence  KSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLLQELAQK
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   .........670.........680.........690.........700.........710.........720
Sequence  AKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPA
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   .........730.........740.........750.........760.........770.........780
Sequence  GALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYA
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   .........790.........800.........810.........820.........830.........840
Sequence  EMYENQAKYKDQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLL
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   .........850.........860.........870.........880.........890.........900
Sequence  DIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVV
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   .........910.........920.........930.........940.........950.........960
Sequence  ELNHAVDSWEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELSHEQETLSFL
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   .........970.........980.........990.........1000.........1010.........1020
Sequence  QLGLAKGEEEGWEYDTFGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLAC
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   .........1030.........1040.........1050.........1060.........1070.........1080
Sequence  EGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDSKTWPWGLDRQFRDP
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   .........1090.........1100.........1110.........1120.........1130.........1140
Sequence  QRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQ
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   .........1150.........1160.........1170.........1180.........1190.........1200
Sequence  TLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMV
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   .........1210.........1220.........1230.........1240.........1250.........1260
Sequence  WLDLQDRILPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSVPWKNGAYTL
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   .........1270.........1280.........1290.........1300.........1310.........1320
Sequence  PKSIQPTIKRMAIEILAWGLRNMKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
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   .........1330.........1340.........1350.........1360.........1370.........1380
Sequence  LVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPT
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   .........1390.........1400.........1410.........1420.........1430.........1440
Sequence  LSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKV
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   .........1450.........1460.........1470.........1480.........1490.........1500
Sequence  YECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQF
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   .........1510.........1520.........1530.........1540.........1550.........1560
Sequence  LVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP
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   .........1570.........1580.........1590.........1600.........1610.........1620
Sequence  IFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYC
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   .........1630.........1640.........1650.........1660.........1670.........1680
Sequence  QSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGL
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   .........1690.........1700.........1710.........1720.........1730.........1740
Sequence  GPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNI
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   .........1750.........1760.........1770.........1780.........1790.........1800
Sequence  NPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKT
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   .........1810.........1820.........1830.........1840.........1850.........1860
Sequence  DIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDND
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   .........1870.........1880.........1890.........1900.........1910.........1920
Sequence  IFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWW
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   .........1930.........1940.........1950.........1960.........1970.........1980
Sequence  PCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLR
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   .........1990.........2000.........2010.........2020.........2030.........2040
Sequence  SPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF
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   .........2050.........2060.........2070.........2080.........2090...
Sequence  NIINSLNTSNASSSILPTQDPNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1dqv chain A

3D model

Region: 1510 - 1877
Aligned: 226
Modelled: 226
Confidence: 99.9%
Identity: 27%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:synaptotagmin iii;
PDBTitle: crystal structure of synaptotagmin iii c2a/c2b

Phyre2

PDB 2r83 chain B

3D model

Region: 1514 - 1877
Aligned: 223
Modelled: 223
Confidence: 99.9%
Identity: 26%
PDB header:endocytosis, exocytosis
Chain: B: PDB Molecule:synaptotagmin-1;
PDBTitle: crystal structure analysis of human synaptotagmin 1 c2a-c2b

Phyre2

PDB 3l9b chain A

3D model

Region: 1 - 128
Aligned: 121
Modelled: 121
Confidence: 99.8%
Identity: 15%
PDB header:membrane protein
Chain: A: PDB Molecule:otoferlin;
PDBTitle: crystal structure of rat otoferlin c2a

Phyre2

PDB 3nsj chain A

3D model

Region: 307 - 394
Aligned: 88
Modelled: 88
Confidence: 99.7%
Identity: 23%
PDB header:immune system
Chain: A: PDB Molecule:perforin-1;
PDBTitle: the x-ray crystal structure of lymphocyte perforin

Phyre2

PDB 2dmh chain A

3D model

Region: 1 - 131
Aligned: 131
Modelled: 131
Confidence: 99.6%
Identity: 34%
PDB header:lipid binding protein
Chain: A: PDB Molecule:myoferlin;
PDBTitle: solution structure of the first c2 domain of human myoferlin

Phyre2

PDB 3kwt chain A

3D model

Region: 308 - 473
Aligned: 115
Modelled: 115
Confidence: 99.6%
Identity: 22%
PDB header:metal binding protein
Chain: A: PDB Molecule:munc13-1;
PDBTitle: munc13-1 c2b-domain, calcium-free

Phyre2

PDB 1gmi chain A

3D model

Region: 1513 - 1610
Aligned: 95
Modelled: 95
Confidence: 99.6%
Identity: 21%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 2cjt chain A domain 1

3D model

Region: 307 - 472
Aligned: 118
Modelled: 118
Confidence: 99.6%
Identity: 25%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 1bdy chain A

3D model

Region: 1514 - 1603
Aligned: 84
Modelled: 84
Confidence: 99.6%
Identity: 15%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 1qas chain A domain 2

3D model

Region: 306 - 472
Aligned: 118
Modelled: 118
Confidence: 99.5%
Identity: 25%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 3jzy chain A

3D model

Region: 1513 - 1603
Aligned: 89
Modelled: 89
Confidence: 99.5%
Identity: 26%
PDB header:endocytosis
Chain: A: PDB Molecule:intersectin 2;
PDBTitle: crystal structure of human intersectin 2 c2 domain

Phyre2

PDB 2fk9 chain A

3D model

Region: 1508 - 1603
Aligned: 93
Modelled: 93
Confidence: 99.5%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, eta type;
PDBTitle: human protein kinase c, eta

Phyre2

PDB 2nq3 chain A

3D model

Region: 308 - 470
Aligned: 121
Modelled: 121
Confidence: 99.5%
Identity: 23%
PDB header:ligase
Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase;
PDBTitle: crystal structure of the c2 domain of human itchy homolog2 e3 ubiquitin protein ligase

Phyre2

PDB 2nq3 chain A domain 1

3D model

Region: 308 - 470
Aligned: 121
Modelled: 121
Confidence: 99.5%
Identity: 23%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 1dsy chain A

3D model

Region: 309 - 437
Aligned: 103
Modelled: 103
Confidence: 99.5%
Identity: 18%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: Synaptotagmin-like (S variant)

Phyre2

PDB 2cjs chain A domain 1

3D model

Region: 309 - 473
Aligned: 127
Modelled: 127
Confidence: 99.5%
Identity: 20%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 3m7f chain B

3D model

Region: 308 - 480
Aligned: 122
Modelled: 122
Confidence: 99.5%
Identity: 20%
PDB header:signaling protein/ligase
Chain: B: PDB Molecule:e3 ubiquitin-protein ligase nedd4;
PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex

Phyre2

PDB 1rlw chain A

3D model

Region: 1514 - 1603
Aligned: 89
Modelled: 89
Confidence: 99.5%
Identity: 27%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 2z0u chain B

3D model

Region: 1510 - 1631
Aligned: 109
Modelled: 108
Confidence: 99.4%
Identity: 18%
PDB header:lipid binding protein
Chain: B: PDB Molecule:ww domain-containing protein 1;
PDBTitle: crystal structure of c2 domain of kibra protein

Phyre2

PDB 1wfj chain A

3D model

Region: 1505 - 1728
Aligned: 129
Modelled: 129
Confidence: 99.4%
Identity: 27%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: Synaptotagmin-like (S variant)

Phyre2

PDB 2cm6 chain A

3D model

Region: 1462 - 1604
Aligned: 119
Modelled: 119
Confidence: 99.3%
Identity: 25%
PDB header:protein transport
Chain: A: PDB Molecule:rabphilin-3a;
PDBTitle: crystal structure of the c2b domain of rabphilin3a

Phyre2

PDB 2k2o chain A

3D model

Region: 840 - 947
Aligned: 108
Modelled: 108
Confidence: 98.9%
Identity: 39%
PDB header:membrane protein
Chain: A: PDB Molecule:myoferlin;
PDBTitle: solution structure of the inner dysf domain of human2 myoferlin

Phyre2

PDB 3hd7 chain A

3D model

Region: 1987 - 2017
Aligned: 31
Modelled: 31
Confidence: 92.9%
Identity: 16%
PDB header:exocytosis
Chain: A: PDB Molecule:vesicle-associated membrane protein 2;
PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1

Phyre2

PDB 1aab chain A

3D model

Region: 1956 - 1981
Aligned: 20
Modelled: 20
Confidence: 59.5%
Identity: 20%
PDB header:dna-binding
Chain: A: PDB Molecule:high mobility group protein;
PDBTitle: nmr structure of rat hmg1 hmga fragment

Phyre2

PDB 1aab chain A

3D model

Region: 1956 - 1981
Aligned: 20
Modelled: 20
Confidence: 59.5%
Identity: 20%
Fold: HMG-box
Superfamily: HMG-box
Family: HMG-box

Phyre2
1

c1dqvA_
2

c2r83B_
3

c3l9bA_
4

c3nsjA_
5

c2dmhA_
6

c3kwtA_
7

d1gmia_
8

d2cjta1
9

d1bdya_
10

d1qasa2
11

c3jzyA_
12

c2fk9A_
13

c2nq3A_
14

d2nq3a1
15

d1dsya_
16

d2cjsa1
17

c3m7fB_
18

d1rlwa_
19

c2z0uB_
20

d1wfja_
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c2cm6A_
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c2k2oA_
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c3hd7A_
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c1aabA_
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d1aaba_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1dqvA_



99.9 27 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:synaptotagmin iii;
PDBTitle: crystal structure of synaptotagmin iii c2a/c2b
2c2r83B_



99.9 26 PDB header:endocytosis, exocytosis
Chain: B: PDB Molecule:synaptotagmin-1;
PDBTitle: crystal structure analysis of human synaptotagmin 1 c2a-c2b
3c3l9bA_



99.8 15 PDB header:membrane protein
Chain: A: PDB Molecule:otoferlin;
PDBTitle: crystal structure of rat otoferlin c2a
4c3nsjA_



99.7 23 PDB header:immune system
Chain: A: PDB Molecule:perforin-1;
PDBTitle: the x-ray crystal structure of lymphocyte perforin
5c2dmhA_



99.6 34 PDB header:lipid binding protein
Chain: A: PDB Molecule:myoferlin;
PDBTitle: solution structure of the first c2 domain of human myoferlin
6c3kwtA_



99.6 22 PDB header:metal binding protein
Chain: A: PDB Molecule:munc13-1;
PDBTitle: munc13-1 c2b-domain, calcium-free
7d1gmia_



99.6 21 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
8d2cjta1



99.6 25 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
9d1bdya_



99.6 15 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
10d1qasa2



99.5 25 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
11c3jzyA_



99.5 26 PDB header:endocytosis
Chain: A: PDB Molecule:intersectin 2;
PDBTitle: crystal structure of human intersectin 2 c2 domain
12c2fk9A_



99.5 17 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, eta type;
PDBTitle: human protein kinase c, eta
13c2nq3A_



99.5 23 PDB header:ligase
Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase;
PDBTitle: crystal structure of the c2 domain of human itchy homolog2 e3 ubiquitin protein ligase
14d2nq3a1



99.5 23 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
15d1dsya_



99.5 18 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
16d2cjsa1



99.5 20 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
17c3m7fB_



99.5 20 PDB header:signaling protein/ligase
Chain: B: PDB Molecule:e3 ubiquitin-protein ligase nedd4;
PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex
18d1rlwa_



99.5 27 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
19c2z0uB_



99.4 18 PDB header:lipid binding protein
Chain: B: PDB Molecule:ww domain-containing protein 1;
PDBTitle: crystal structure of c2 domain of kibra protein
20d1wfja_



99.4 27 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
21d2ep6a1



not modelled 99.4 25 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
22c2d8kA_



not modelled 99.4 30 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:synaptotagmin vii;
PDBTitle: solution structure of the first c2 domain of synaptotagmin2 vii
23c3fbkB_



not modelled 99.4 17 PDB header:signaling protein
Chain: B: PDB Molecule:regulator of g-protein signaling 3;
PDBTitle: crystal structure of the c2 domain of the human regulator2 of g-protein signaling 3 isoform 6 (rgp3), northeast3 structural genomics consortium target hr5550a
24c2q3xA_



not modelled 99.4 27 PDB header:transport protein
Chain: A: PDB Molecule:regulating synaptic membrane exocytosis protein 1;
PDBTitle: the rim1alpha c2b domain
25d2r83a1



not modelled 99.4 27 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
26d1a25a_



not modelled 99.4 31 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
27c2jqzA_



not modelled 99.4 20 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2;
PDBTitle: solution structure of the c2 domain of human smurf2
28c2chdA_



not modelled 99.4 31 PDB header:protein transport
Chain: A: PDB Molecule:rabphilin-3a;
PDBTitle: crystal structure of the c2a domain of rabphilin-3a
29c2nsqA_



not modelled 99.4 25 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4-like protein;
PDBTitle: crystal structure of the c2 domain of the human e3 ubiquitin-protein2 ligase nedd4-like protein
30d1ugka_



not modelled 99.3 29 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
31c1djyB_



not modelled 99.3 27 PDB header:lipid degradation
Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c,
PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
32c2enpA_



not modelled 99.3 24 PDB header:transport protein
Chain: A: PDB Molecule:b/k protein;
PDBTitle: solution structure of the first c2 domain from human b/k2 protein
33d1v27a_



not modelled 99.3 24 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
34d2zkmx2



not modelled 99.3 26 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
35d1wfma_



not modelled 99.3 19 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
36d1rsya_



not modelled 99.3 29 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
37c2cm6A_



99.3 25 PDB header:protein transport
Chain: A: PDB Molecule:rabphilin-3a;
PDBTitle: crystal structure of the c2b domain of rabphilin3a
38d2cm5a1



not modelled 99.3 28 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
39d1dqva1



not modelled 99.2 31 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
40c2enjA_



not modelled 99.2 19 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c theta type;
PDBTitle: solution sturcture of the c2 domain from human protein2 kinase c theta
41c2b3rA_



not modelled 99.2 23 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4-phosphate 3-kinase c2 domain-
PDBTitle: crystal structure of the c2 domain of class ii phosphatidylinositide2 3-kinase c2
42c2dmgA_



not modelled 99.2 22 PDB header:lipid binding protein
Chain: A: PDB Molecule:kiaa1228 protein;
PDBTitle: solution structure of the third c2 domain of kiaa12282 protein
43d1rh8a_



not modelled 99.2 29 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
44d1dqva2



not modelled 99.2 26 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
45d2bwqa1



not modelled 99.2 25 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
46d1uowa_



not modelled 99.1 25 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
47c3n5aA_



not modelled 99.1 28 PDB header:protein transport
Chain: A: PDB Molecule:synaptotagmin-7;
PDBTitle: synaptotagmin-7, c2b-domain, calcium bound
48c1cjyB_



not modelled 99.1 15 PDB header:hydrolase
Chain: B: PDB Molecule:protein (cytosolic phospholipase a2);
PDBTitle: human cytosolic phospholipase a2
49d1byna_



not modelled 99.1 30 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
50c3fdwA_



not modelled 99.0 16 PDB header:lipid binding protein
Chain: A: PDB Molecule:synaptotagmin-like protein 4;
PDBTitle: crystal structure of a c2 domain from human synaptotagmin-2 like protein 4
51c2k2oA_



98.9 39 PDB header:membrane protein
Chain: A: PDB Molecule:myoferlin;
PDBTitle: solution structure of the inner dysf domain of human2 myoferlin
52c3qr0A_



not modelled 98.9 28 PDB header:hydrolase
Chain: A: PDB Molecule:phospholipase c-beta (plc-beta);
PDBTitle: crystal structure of s. officinalis plc21
53d1w15a_



not modelled 98.9 24 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
54c2fjuB_



not modelled 98.8 31 PDB header:signaling protein,apoptosis/hydrolase
Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: activated rac1 bound to its effector phospholipase c beta 2
55c3ohmB_



not modelled 98.7 17 PDB header:signaling protein / hydrolase
Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
56c2enqA_



not modelled 97.3 20 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase
PDBTitle: solution structure of the c2 domain from human pi3-kinase2 p110 subunit alpha
57c3pfqA_



not modelled 97.0 32 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
58d1e7ua2



not modelled 97.0 16 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
59c2wxoA_



not modelled 96.8 20 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: the crystal structure of the murine class ia pi 3-kinase2 p110delta in complex with as5.
60d1e8ya2



not modelled 96.2 19 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
61d1whna_



not modelled 94.7 23 Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
62c1e8zA_



not modelled 94.5 22 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol 3-kinase catalytic subunit;
PDBTitle: structure determinants of phosphoinositide 3-kinase2 inhibition by wortmannin, ly294002, quercetin, myricetin3 and staurosporine
63c2rd0A_



not modelled 94.5 19 PDB header:transferase/oncoprotein
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: structure of a human p110alpha/p85alpha complex
64c2y3aA_



not modelled 93.4 18 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
65c3hd7A_



92.9 16 PDB header:exocytosis
Chain: A: PDB Molecule:vesicle-associated membrane protein 2;
PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1
66c3l4cB_



not modelled 90.0 16 PDB header:cell adhesion, cell invasion, apoptosis
Chain: B: PDB Molecule:dedicator of cytokinesis protein 1;
PDBTitle: structural basis of membrane-targeting by dock180
67c1aabA_



59.5 20 PDB header:dna-binding
Chain: A: PDB Molecule:high mobility group protein;
PDBTitle: nmr structure of rat hmg1 hmga fragment
68d1aaba_



59.5 20 Fold:HMG-box
Superfamily:HMG-box
Family:HMG-box
69c3htxA_



not modelled 57.3 19 PDB header:transferase/rna
Chain: A: PDB Molecule:hen1;
PDBTitle: crystal structure of small rna methyltransferase hen1
70c3adlA_



not modelled 52.4 17 PDB header:gene regulation/rna
Chain: A: PDB Molecule:risc-loading complex subunit tarbp2;
PDBTitle: structure of trbp2 and its molecule implications for mirna processing
71d1di2a_



not modelled 51.4 19 Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
72d1q42a_



not modelled 50.0 22 Fold:Cystatin-like
Superfamily:NTF2-like
Family:NTF2-like
73d1d5ra1



not modelled 48.9 16 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
74d1of5b_



not modelled 46.3 22 Fold:Cystatin-like
Superfamily:NTF2-like
Family:NTF2-like
75c1q40C_



not modelled 45.2 22 PDB header:translation
Chain: C: PDB Molecule:mrna transport regulator mtr2;
PDBTitle: crystal structure of the c. albicans mtr2-mex67 m domain complex
76c2zv4O_



not modelled 43.6 25 PDB header:structural protein
Chain: O: PDB Molecule:major vault protein;
PDBTitle: the structure of rat liver vault at 3.5 angstrom resolution
77d1vf5b_



not modelled 42.7 16 Fold:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Superfamily:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Family:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
78c3nngA_



not modelled 39.3 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the f5/8 type c domain of q5lfr2_bacfn protein2 from bacteroides fragilis. northeast structural genomics consortium3 target bfr258e
79d2g3wa1



not modelled 38.3 24 Fold:Restriction endonuclease-like
Superfamily:Restriction endonuclease-like
Family:YaeQ-like
80d1q90d_



not modelled 38.1 15 Fold:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Superfamily:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Family:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
81c3ipdB_



not modelled 35.8 15 PDB header:exocytosis
Chain: B: PDB Molecule:syntaxin-1a;
PDBTitle: helical extension of the neuronal snare complex into the2 membrane, spacegroup i 21 21 21
82d2dixa1



not modelled 33.6 19 Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
83c1j3xA_



not modelled 33.0 24 PDB header:dna binding protein
Chain: A: PDB Molecule:high mobility group protein 2;
PDBTitle: solution structure of the n-terminal domain of the hmgb2
84d1j3xa_



not modelled 33.0 24 Fold:HMG-box
Superfamily:HMG-box
Family:HMG-box
85d1ekza_



not modelled 32.7 9 Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
86c2yvxD_



not modelled 32.3 8 PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
87c3dinD_



not modelled 31.4 18 PDB header:membrane protein, protein transport
Chain: D: PDB Molecule:preprotein translocase subunit sece;
PDBTitle: crystal structure of the protein-translocation complex formed by the2 secy channel and the seca atpase
88c2yewB_



not modelled 31.0 13 PDB header:virus
Chain: B: PDB Molecule:e1 envelope glycoprotein;
PDBTitle: modeling barmah forest virus structural proteins
89d2qpva1



not modelled 30.6 21 Fold:TBP-like
Superfamily:Bet v1-like
Family:Atu1531-like
90d1uhza_



not modelled 30.2 13 Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
91c3adjA_



not modelled 30.1 20 PDB header:gene regulation
Chain: A: PDB Molecule:f21m12.9 protein;
PDBTitle: structure of arabidopsis hyl1 and its molecular implications for mirna2 processing
92c3oc3B_



not modelled 29.4 15 PDB header:hydrolase/transcription
Chain: B: PDB Molecule:helicase mot1;
PDBTitle: crystal structure of the mot1 n-terminal domain in complex with tbp
93d2ot9a1



not modelled 29.3 21 Fold:Restriction endonuclease-like
Superfamily:Restriction endonuclease-like
Family:YaeQ-like
94d2cpna1



not modelled 28.7 26 Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
95d2e74b1



not modelled 26.3 12 Fold:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Superfamily:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Family:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
96c3llhB_



not modelled 25.6 35 PDB header:rna binding protein
Chain: B: PDB Molecule:risc-loading complex subunit tarbp2;
PDBTitle: crystal structure of the first dsrbd of tar rna-binding protein 2
97c3s9jA_



not modelled 25.5 24 PDB header:unknown function
Chain: A: PDB Molecule:member of duf4221 family;
PDBTitle: crystal structure of a member of duf4221 family (bvu_1028) from2 bacteroides vulgatus atcc 8482 at 1.75 a resolution
98c2yt4A_



not modelled 25.1 19 PDB header:rna binding protein
Chain: A: PDB Molecule:protein dgcr8;
PDBTitle: crystal structure of human dgcr8 core
99d2yrba1



not modelled 24.9 16 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
100d1x47a1



not modelled 24.8 19 Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
101d1pf4a2



not modelled 23.6 15 Fold:ABC transporter transmembrane region
Superfamily:ABC transporter transmembrane region
Family:ABC transporter transmembrane region
102c4drvA_



not modelled 23.4 21 PDB header:viral protein
Chain: A: PDB Molecule:outer capsid protein vp4;
PDBTitle: cell attachment protein vp8* of a human rotavirus specifically2 interacts with a-type histo-blood group antigen
103c3n0aA_



not modelled 23.1 7 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase auxilin;
PDBTitle: crystal structure of auxilin (40-400)
104c2l2nA_



not modelled 22.5 38 PDB header:rna binding protein, plant protein
Chain: A: PDB Molecule:hyponastic leave 1;
PDBTitle: backbone 1h, 13c, and 15n chemical shift assignments for the first2 dsrbd of protein hyl1
105d1j3da_



not modelled 22.5 32 Fold:HMG-box
Superfamily:HMG-box
Family:HMG-box
106d2aaib1



not modelled 22.5 8 Fold:beta-Trefoil
Superfamily:Ricin B-like lectins
Family:Ricin B-like
107d1stua_



not modelled 22.4 5 Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
108c2eqzA_



not modelled 22.0 11 PDB header:transcription
Chain: A: PDB Molecule:high mobility group protein b3;
PDBTitle: solution structure of the first hmg-box domain from high2 mobility group protein b3
109c2yrqA_



not modelled 20.3 22 PDB header:dna binding protein
Chain: A: PDB Molecule:high mobility group protein b1;
PDBTitle: solution structure of the tandem hmg box domain from human2 high mobility group protein b1
110d1z1ba1



not modelled 20.3 24 Fold:DNA-binding domain
Superfamily:DNA-binding domain
Family:lambda integrase N-terminal domain

Binding site prediction 

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