Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionC1P618
DateWed Jan 25 15:20:08 GMT 2012
Unique Job IDa4c3a4e048d67f12

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2vogB_
Top template information
PDB header:apoptosis
Chain: B: PDB Molecule:bcl-2-modifying factor;
PDBTitle: structure of mouse a1 bound to the bmf bh3-domain
Confidence and coverage
Confidence: 40.5% Coverage: 23%
6 residues ( 23% of your sequence) have been modelled with 40.5% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20......
Sequence  MKIADQFHDELCRLAAINFEAHVLHG
Secondary structure 





SS confidence 

























Disorder  ????
















?????
Disorder confidence 

























 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2vog chain B

3D model

Region: 3 - 8
Aligned: 6
Modelled: 6
Confidence: 40.5%
Identity: 100%
PDB header:apoptosis
Chain: B: PDB Molecule:bcl-2-modifying factor;
PDBTitle: structure of mouse a1 bound to the bmf bh3-domain

Phyre2

PDB 2fz0 chain A

3D model

Region: 3 - 11
Aligned: 9
Modelled: 9
Confidence: 22.3%
Identity: 67%
PDB header:membrane protein
Chain: A: PDB Molecule:v-snare component of the vacuolar snare complex
PDBTitle: identification of yeast r-snare nyv1p as a novel longin2 domain protein

Phyre2

PDB 1xeq chain A domain 1

3D model

Region: 15 - 24
Aligned: 10
Modelled: 10
Confidence: 7.7%
Identity: 70%
Fold: S15/NS1 RNA-binding domain
Superfamily: S15/NS1 RNA-binding domain
Family: N-terminal, RNA-binding domain of nonstructural protein NS1

Phyre2
1

c2vogB_
2

c2fz0A_
3

d1xeqa1



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2vogB_



40.5 100 PDB header:apoptosis
Chain: B: PDB Molecule:bcl-2-modifying factor;
PDBTitle: structure of mouse a1 bound to the bmf bh3-domain
2c2fz0A_



22.3 67 PDB header:membrane protein
Chain: A: PDB Molecule:v-snare component of the vacuolar snare complex
PDBTitle: identification of yeast r-snare nyv1p as a novel longin2 domain protein
3d1xeqa1



7.7 70 Fold:S15/NS1 RNA-binding domain
Superfamily:S15/NS1 RNA-binding domain
Family:N-terminal, RNA-binding domain of nonstructural protein NS1

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0