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Job DescriptionQ95XA9
Confidence99.96%DateSun Jun 30 11:04:27 BST 2013
Rank10Aligned Residues200
% Identity20%Templatec1a81E_
PDB info PDB header:complex (transferase/peptide)Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
Resolution3.00 Å
Model Dimensions (Å)X:59.768 Y:47.584 Z:33.107

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   36...40.........50. ........60.... .....70.........80.........90.
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Query Sequence  WYHGELNEHDANHLLQ. . GTSPGAFLVRQTG. . QTRFYLSILDQDGYPKHLPIRQLTPPH
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Template Sequence  FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA. HHYTIERELNGT
Template Known Secondary structure  TSS

TTT

TT
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   15....20.........30.........40.........50.........60. ........70...
 
   92.. .....100.........110.........120.........130.........140.........150
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Query Sequence  YFF. EGKRFETLRDIVDAYQLAVIPVRKGGIMPINGEIQETKYLCVRRFEQREIDEMNSE
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Template Sequence  YAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRP. . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTS

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   74.....80.........90.........100.........110
 
   151........160.........170.........180.........190.........200.......
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Query Sequence  IGDILSVCETDETGWMLGRNETSGSVGIILRSHLEPLITEVADLSDLPYFYDTVSTD. . .
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . QGVQPKTPQLEKLIATTAHEKMPWFHGKISREESE
Template Known Secondary structure  .........................TT






TSGGG
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   111........120.........130.........140.....
 
   208.210.........220.........230.........240.........250......... 260...
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Query Sequence  . . . MVQYSPIGTFLLRRSSKGTDTYALLVKTQFDLVEKFLIVGCPSRGFSLAGRP. FPTI
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Template Sequence  QIVLIGSKTNGKFLIRAR. DNNGSYALCLLHE. GKVLHYRIDKDKTGKLSIPEGKKFDTL
Template Known Secondary structure  SS


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   180.........190....... ..200.........210 .........220.........230.......
 
   264.....270.........280......
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Query Sequence  GHVLTRYCDRAISGGVRLTHAVC
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Template Sequence  WQLVEHYSYKADGLLRVLTVPCQ
Template Known Secondary structure  TT

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   238.240.........250.........260
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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