Emaill.a.kelley@imperial.ac.uk
DescriptionQ95XA9
DateSun Jun 30 11:04:27 BST 2013
Unique Job IDe743689df95aa392

Detailed template information 

#Template Alignment Coverage3D Model Confidence% i.d. Template Information
1c3bxjB_



100.0 17 PDB header:signaling protein
Chain: B: PDB Molecule:ras gtpase-activating protein syngap;
PDBTitle: crystal structure of the c2-gap fragment of syngap
2d1wera_



100.0 17 Fold:GTPase activation domain, GAP
Superfamily:GTPase activation domain, GAP
Family:p120GAP domain-like
3d1nf1a_



100.0 18 Fold:GTPase activation domain, GAP
Superfamily:GTPase activation domain, GAP
Family:p120GAP domain-like
4c2b3oA_



100.0 24 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
5c2shpA_



100.0 21 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
6c3fayA_



100.0 17 PDB header:membrane protein
Chain: A: PDB Molecule:ras gtpase-activating-like protein iqgap1;
PDBTitle: crystal structure of the gap-related domain of iqgap1
7c3gqiB_



100.0 23 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
8c3ps5A_



100.0 25 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
9c2oq1A_



100.0 19 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
10c1a81E_



100.0 20 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
11c4fl2A_



100.0 19 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
12c2ozoA_



99.9 18 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
13c2lqnA_



99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
14c2ablA_



99.9 15 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
15c2fo0A_



99.9 15 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
16c2eyyA_



99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
17c1x27F_



99.9 21 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
18c1k9aB_



99.9 19 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
19c3nhnA_



99.9 21 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
20c3qwyA_



99.9 18 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
21c2h8hA_



not modelled 99.9 20 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
22c1y57A_



not modelled 99.9 20 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
23c1oplA_



not modelled 99.9 14 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
24c1g83A_



not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
25c2dvjA_



not modelled 99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
26c3qwxX_



not modelled 99.9 16 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
27c2eyzA_



not modelled 99.9 30 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
28c2xp1A_



not modelled 99.8 17 PDB header:transcription
Chain: A: PDB Molecule:spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
29c2c0iA_



not modelled 99.8 20 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
30c3or8A_



not modelled 99.8 19 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
31c2gsbA_



not modelled 99.6 24 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
32c2eo3A_



not modelled 99.5 22 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
33c2hdxB_



not modelled 99.5 22 PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
34d2oq1a1



not modelled 99.5 18 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
35c2crhA_



not modelled 99.5 25 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
36d1fhsa_



not modelled 99.5 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
37c2vifA_



not modelled 99.5 21 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
38c2dcrA_



not modelled 99.5 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
39d1i3za_



not modelled 99.5 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
40c2dlyA_



not modelled 99.5 22 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
41d2oq1a2



not modelled 99.5 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
42c2ci8A_



not modelled 99.5 28 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
43d1a81a2



not modelled 99.5 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
44d1xa6a2



not modelled 99.5 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
45c2y3aB_



not modelled 99.5 23 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
46c2kk6A_



not modelled 99.5 28 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
47c3hizB_



not modelled 99.5 22 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
48d2shpa2



not modelled 99.5 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
49c2dlzA_



not modelled 99.5 23 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
50d3c7ia1



not modelled 99.5 18 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
51d1a81e2



not modelled 99.5 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
52d1csya_



not modelled 99.5 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
53c2eobA_



not modelled 99.5 22 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
54d1rjaa_



not modelled 99.5 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
55c2ysxA_



not modelled 99.5 17 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
56c1x6cA_



not modelled 99.4 26 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
57d1jwoa_



not modelled 99.4 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
58c2eo6A_



not modelled 99.4 20 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
59d1ayaa_



not modelled 99.4 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
60d2shpa3



not modelled 99.4 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
61d1k9aa2



not modelled 99.4 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
62d1r1qa_



not modelled 99.4 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
63c1ka6A_



not modelled 99.4 17 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
64d1a81a1



not modelled 99.4 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
65d1jyra_



not modelled 99.4 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
66d1opka2



not modelled 99.4 15 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
67d1pica_



not modelled 99.4 17 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
68d1blja_



not modelled 99.4 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
69c2lctA_



not modelled 99.4 31 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
70d1mila_



not modelled 99.4 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
71d2izva2



not modelled 99.4 19 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
72d2cs0a1



not modelled 99.4 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
73d1a81e1



not modelled 99.4 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
74d1nrva_



not modelled 99.4 18 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
75d1qada_



not modelled 99.4 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
76c2c9wA_



not modelled 99.4 23 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
77c2augB_



not modelled 99.4 31 PDB header:signaling protein
Chain: B: PDB Molecule:growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
78d2eyva1



not modelled 99.4 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
79c2el8A_



not modelled 99.4 17 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
80c1rqqC_



not modelled 99.4 27 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
81d2fcia1



not modelled 99.4 10 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
82d1rpya_



not modelled 99.3 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
83c2d9zA_



99.3 17 PDB header:signaling protein
Chain: A: PDB Molecule:protein kinase c, nu type;
PDBTitle: solution structure of the ph domain of protein kinase c, nu2 type from human
84d1o48a_



not modelled 99.3 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
85d1cwea_



not modelled 99.3 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
86d1lkka_



not modelled 99.3 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
87c1griA_



not modelled 99.3 24 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
88d1qcfa2



not modelled 99.3 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
89d1g83a2



not modelled 99.3 36 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
90c3fehA_



99.3 12 PDB header:hydrolase activator
Chain: A: PDB Molecule:centaurin-alpha-1;
PDBTitle: crystal structure of full length centaurin alpha-1
91d1bkla_



not modelled 99.3 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
92d1d4ta_



not modelled 99.3 17 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
93d2coaa1



99.3 12 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
94c2r09A_



99.3 16 PDB header:signaling protein
Chain: A: PDB Molecule:cytohesin-3;
PDBTitle: crystal structure of autoinhibited form of grp1 arf gtpase exchange2 factor
95c2knoA_



not modelled 99.3 25 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
96d2fjla1



99.3 16 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
97d2c9wa2



not modelled 99.3 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
98d1f2fa_



not modelled 99.3 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
99c2ge9A_



not modelled 99.3 20 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
100d1luia_



not modelled 99.3 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
101c2izvA_



not modelled 99.3 19 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
102c3mazA_



not modelled 99.3 14 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
103c2lulA_



99.2 17 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase tec;
PDBTitle: solution nmr structure of ph domain of tyrosine-protein kinase tec2 from homo sapiens, northeast structural genomics consortium (nesg)3 target hr3504c
104d2dyna_



not modelled 99.2 12 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
105c2dhiA_



not modelled 99.2 23 PDB header:signaling protein
Chain: A: PDB Molecule:pleckstrin homology domain-containing family b
PDBTitle: solution structure of the ph domain of evectin-2 from mouse
106c2d9vA_



not modelled 99.2 19 PDB header:membrane protein
Chain: A: PDB Molecule:pleckstrin homology domain-containing protein
PDBTitle: solution structure of the ph domain of pleckstrin homology2 domain-containing protein family b member 1 from mouse
107c3gxxB_



not modelled 99.2 22 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
108c2ekxA_



not modelled 99.2 20 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
109d2qmsa1



not modelled 99.2 16 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
110c2dm0A_



not modelled 99.2 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
111c2hmhA_



not modelled 99.2 23 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
112d1v88a_



not modelled 99.2 22 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
113d1fu6a_



not modelled 99.2 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
114c3a8qB_



not modelled 99.2 19 PDB header:signaling protein
Chain: B: PDB Molecule:t-lymphoma invasion and metastasis-inducing
PDBTitle: low-resolution crystal structure of the tiam2 phccex domain
115c1xa6A_



not modelled 99.2 24 PDB header:signaling protein
Chain: A: PDB Molecule:beta2-chimaerin;
PDBTitle: crystal structure of the human beta2-chimaerin
116d1u5ea1



not modelled 99.2 11 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
117d1wgqa_



not modelled 99.2 13 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
118c2dn6A_



not modelled 99.1 13 PDB header:signaling protein
Chain: A: PDB Molecule:kiaa0640 protein;
PDBTitle: solution structure of the ph domain of kiaa0640 protein2 from human
119d1xx0a1



not modelled 99.1 12 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
120d2cofa1



not modelled 99.1 15 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)