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Job DescriptionO61768
Confidence100.00%DateSat Apr 13 13:04:39 BST 2013
Rank5Aligned Residues245
% Identity29%Templatec2h8hA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
Resolution2.20 Å
Model Dimensions (Å)X:64.138 Y:58.594 Z:41.528

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   4.....10.........20....... ..30.........40.........50..... ....60.........70....
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Query Sequence  KDLLHQKYYHGLLPREDIQEMLNK. . . . PGQFLLRTSEPVKGEKRQFVLSVVGEKK. . . . . TSANHFVVRESDHKVYVDK
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Template Sequence  DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGA. . . YCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSR
Template Known Secondary structure  TSGGGSTTB

S

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TT
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   141........150.........160.........170.........180... ......190.........200.........210.......
 
   75....80.........90.........100.... .....110.........120.........130.........140.........150.
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Query Sequence  IGFPTIIELVNHYVSTKESFSTKDGTVKAV. . . LKQAVERQKWELYHEDVELTKKLGEGAFGEVWKGKLLKILDANHQPV
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Template Sequence  TQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNG. . . . . . . TT
Template Known Secondary structure  SS

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SSSSTT
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   218.220.........230.........240.........250.........260.........270.........280........ .290
 
   152.......160.........170.........180.........190.........200.........210..... ....220........
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Query Sequence  LVAVKTAKLESMTKEQIKEIMREARLMRNLDHINVVKFFGVAAGTEPLYVIMELADGGALDSAL. . . GKLHFPMIKKYEL
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Template Sequence  RVAIKTLKPGTMSP. . . EAFLQEAQVMKKLRHEKLVQLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDM
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   291........300.... .....310.........320.........330 .........340.........350.........360......
 
   229230.........240.........250.........260..
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Query Sequence  IYQAANGLAYIHEKNLMHRDVAARNCLYGGGQVL
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Template Sequence  AAQIASGMAYVERMNYVHRDLRAANILVGENLVC
Template Known Secondary structure  TT


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SGGG
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   367..370.........380.........390.........400
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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