Emaill.a.kelley@imperial.ac.uk
DescriptionQ95PX0
DateSat Apr 13 13:19:58 BST 2013
Unique Job ID957911be8e771a01

Detailed template information 

#Template Alignment Coverage3D Model Confidence% i.d. Template Information
1c2fo0A_



100.0 40 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
2c1k9aB_



100.0 32 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
3c2ablA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
4c1oplA_



100.0 42 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
5c1y57A_



100.0 40 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
6c3nhnA_



100.0 38 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
7c1x27F_



100.0 37 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
8c2h8hA_



100.0 40 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
9c2c0iA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
10c1g83A_



100.0 37 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
11c2lqnA_



100.0 18 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
12c1griA_



100.0 27 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
13c2l3sA_



100.0 18 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
14c2eyzA_



100.0 18 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
15c1ng2A_



100.0 26 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
16c2b3oA_



100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
17c2eo3A_



100.0 38 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
18c3ps5A_



100.0 22 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
19c1ov3A_



100.0 28 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
20c2shpA_



100.0 23 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
21c2eo6A_



not modelled 100.0 21 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
22c3hizB_



not modelled 99.9 34 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
23c2hdxB_



not modelled 99.9 27 PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
24c2kk6A_



not modelled 99.9 31 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
25c2ci8A_



not modelled 99.9 48 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
26d3c7ia1



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
27c2crhA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
28c2dcrA_



not modelled 99.9 28 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
29c2gsbA_



not modelled 99.9 33 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
30c2vifA_



not modelled 99.9 32 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
31d2shpa2



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
32d1fhsa_



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
33c2dlzA_



not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
34d2izva2



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
35d2eyva1



not modelled 99.9 37 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
36d1mila_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
37c2dlyA_



not modelled 99.9 33 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
38c1x6cA_



not modelled 99.9 32 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
39d1jwoa_



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
40c2c9wA_



not modelled 99.9 31 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
41d2oq1a1



not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
42d1rjaa_



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
43c2y3aB_



not modelled 99.9 25 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
44c2eobA_



not modelled 99.9 28 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
45c2oq1A_



not modelled 99.9 27 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
46c2hmhA_



not modelled 99.9 22 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
47d1pica_



not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
48d1a81e1



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
49d1opka2



not modelled 99.9 36 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
50d1a81a2



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
51c2izvA_



not modelled 99.9 27 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
52d2oq1a2



not modelled 99.9 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
53d1nrva_



not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
54c2lctA_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
55d1fu6a_



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
56d1k9aa2



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
57c1a81E_



not modelled 99.9 18 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
58d1a81e2



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
59c2augB_



not modelled 99.9 33 PDB header:signaling protein
Chain: B: PDB Molecule:growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
60d1r1qa_



not modelled 99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
61c3gqiB_



not modelled 99.9 25 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
62c1ka6A_



not modelled 99.9 29 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
63d1ayaa_



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
64d1blja_



not modelled 99.9 36 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
65d1a81a1



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
66c2ozoA_



not modelled 99.9 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
67d1d4ta_



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
68d2fcia1



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
69d1csya_



not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
70d1jyra_



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
71d2shpa3



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
72c2ysxA_



not modelled 99.9 26 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
73d1i3za_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
74d1qada_



not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
75d2cs0a1



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
76d1lkka_



not modelled 99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
77d1o48a_



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
78c4fl2A_



not modelled 99.9 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
79d2qmsa1



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
80d2c9wa2



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
81c2ge9A_



not modelled 99.9 29 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
82d1qcfa2



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
83c2el8A_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
84c2knoA_



not modelled 99.9 26 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
85d1f2fa_



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
86d1bkla_



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
87d1xa6a2



not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
88d1g83a2



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
89d1rpya_



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
90c1rqqC_



not modelled 99.9 28 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
91c2ekxA_



not modelled 99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
92c2cr4A_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
93c3mazA_



not modelled 99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
94d1luia_



not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
95c2dm0A_



not modelled 99.9 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
96c2dvjA_



not modelled 99.8 36 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
97d1cwea_



not modelled 99.8 41 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
98c3qwxX_



not modelled 99.8 36 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
99c3gxxB_



not modelled 99.8 25 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
100c3qwyA_



not modelled 99.8 36 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
101c2eyyA_



not modelled 99.8 35 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
102c2dybA_



not modelled 99.8 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: the crystal structure of human p40(phox)
103c2dx0B_



not modelled 99.8 34 PDB header:hydrolase
Chain: B: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
104c2yt6A_



not modelled 99.8 34 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
105c1mv3A_



not modelled 99.7 19 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
106d1udla_



not modelled 99.7 39 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
107d1ng2a2



not modelled 99.7 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
108c3or8A_



not modelled 99.7 24 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
109c1wx6A_



not modelled 99.7 35 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:cytoplasmic protein nck2;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2
110c2xp1A_



not modelled 99.7 17 PDB header:transcription
Chain: A: PDB Molecule:spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
111c2yuoA_



not modelled 99.7 28 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
112c2kymA_



not modelled 99.7 21 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
113c2yunA_



not modelled 99.7 35 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
114c1xa6A_



not modelled 99.7 24 PDB header:signaling protein
Chain: A: PDB Molecule:beta2-chimaerin;
PDBTitle: crystal structure of the human beta2-chimaerin
115c3jv3A_



not modelled 99.7 31 PDB header:protein binding
Chain: A: PDB Molecule:intersectin-1;
PDBTitle: structure of sh3e-dh unit of murine intersectin-1l
116c2dx1A_



not modelled 99.7 28 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
117c3nmzD_



not modelled 99.7 27 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
118c1x2qA_



not modelled 99.7 26 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
119d1k4us_



not modelled 99.7 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
120c2ekhA_



not modelled 99.7 25 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418