BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (713 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q2M385 Macrophage-expressed gene 1 protein n=18 Tax=Mam...  1137   0.0  
UniRef50_Q7SXE0 Macrophage expressed 1 n=10 Tax=Clupeocephala Re...   669   0.0  
UniRef50_UPI0000EBD8A9 PREDICTED: similar to macrophage expresse...   506   e-141
UniRef50_UPI0000F2D8B8 PREDICTED: similar to Macrophage expresse...   495   e-138
UniRef50_Q80VB7 Mpeg1 protein (Fragment) n=1 Tax=Mus musculus Re...   480   e-134
UniRef50_UPI0001796D85 PREDICTED: similar to Macrophage-expresse...   470   e-130
UniRef50_Q6RYF9 Macrophage expressed protein n=5 Tax=Eumetazoa R...   460   e-128
UniRef50_A7SEK6 Predicted protein (Fragment) n=1 Tax=Nematostell...   456   e-126
UniRef50_B3F732 Macrophage expressed protein 1-like protein n=1 ...   442   e-122
UniRef50_Q4W1E5 Macrophage expressed protein n=1 Tax=Suberites d...   380   e-103
UniRef50_C4Q3P0 Expressed protein n=2 Tax=Schistosoma RepID=C4Q3...   276   3e-72
UniRef50_Q2XSC0 Macrophage expressed protein (Fragment) n=1 Tax=...   230   1e-58
UniRef50_Q5BVJ5 SJCHGC08097 protein (Fragment) n=1 Tax=Schistoso...    86   5e-15
UniRef50_O76288 Apextrin n=4 Tax=Echinoida RepID=O76288_HELER          47   0.002
UniRef50_UPI0000E49992 PREDICTED: similar to apextrin n=17 Tax=S...    47   0.003

>UniRef50_Q2M385 Macrophage-expressed gene 1 protein n=18 Tax=Mammalia
           RepID=MPEG1_HUMAN
          Length = 716

 Score = 1137 bits (2941), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 542/716 (75%), Positives = 621/716 (86%), Gaps = 3/716 (0%)

Query: 1   MNSFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMG 60
           MN+F A +L W   A A++ KP GE    G Q CKNALKLPVLEVLPGGGWDNLRNVDMG
Sbjct: 1   MNNFRATILFWAAAAWAKSGKPSGEMDEVGVQKCKNALKLPVLEVLPGGGWDNLRNVDMG 60

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA 120
           RVM+LTY+NC+TTEDGQYIIPDE++TIPQK+SNLEMNSE+LESW NYQS+TS SINTEL+
Sbjct: 61  RVMELTYSNCRTTEDGQYIIPDEIFTIPQKQSNLEMNSEILESWANYQSSTSYSINTELS 120

Query: 121 LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICD 180
           LFS+VNGKFSTEFQRMKTLQVKDQA+TTRVQVRN +YTVK  PT ELS GF K L+DI D
Sbjct: 121 LFSKVNGKFSTEFQRMKTLQVKDQAITTRVQVRNLVYTVKINPTLELSSGFRKELLDISD 180

Query: 181 QLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASA 240
           +LE NQT+MATYLAELL+LNYGTHV TSVDAGAAL+QEDH+R+SFL D+Q+S++ VTASA
Sbjct: 181 RLENNQTRMATYLAELLVLNYGTHVTTSVDAGAALIQEDHLRASFLQDSQSSRSAVTASA 240

Query: 241 GIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHL 300
           G+AF N VNFK E +Y SQ  LTK YLSNRTNSRVQS GGVPFYPGITL+ WQ+GITNHL
Sbjct: 241 GLAFQNTVNFKFEENYTSQNVLTKSYLSNRTNSRVQSIGGVPFYPGITLQAWQQGITNHL 300

Query: 301 VAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNF 360
           VAIDR+GLPLHFFI P+ LP LPGPLVKK+SKTVETAV+ YYTFNT+PGCT+++SPNFNF
Sbjct: 301 VAIDRSGLPLHFFINPNMLPDLPGPLVKKVSKTVETAVKRYYTFNTYPGCTDLNSPNFNF 360

Query: 361 QANMDDDSCDAKVTNFTFGGVYQECTELSGD---VLCQNLEQKNLLTGDFSCPPGYSPVH 417
           QAN DD SC+ K+TNF+FGGVYQECT+LSG+   +LCQ LEQKN LTGDFSCP GYSPVH
Sbjct: 361 QANTDDGSCEGKMTNFSFGGVYQECTQLSGNRDVLLCQKLEQKNPLTGDFSCPSGYSPVH 420

Query: 418 LLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFG 477
           LLSQ HEEGY+ LEC +KCTL +FCKTVCEDVF+VAKAEFRA+WCVA+ QVP+NSGLLFG
Sbjct: 421 LLSQIHEEGYNHLECHRKCTLLVFCKTVCEDVFQVAKAEFRAFWCVASSQVPENSGLLFG 480

Query: 478 GVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPL 537
           G+F+ K+INPMTNAQSCPAGY PL LFE+LKVCVS DYELG +F+VPFGGFFSC +GNPL
Sbjct: 481 GLFSSKSINPMTNAQSCPAGYFPLRLFENLKVCVSQDYELGSRFAVPFGGFFSCTVGNPL 540

Query: 538 VNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP 597
           V+   ++D+ APSLKKCPGGFSQH A+ISDGCQVSYCVK+G+FTGGSL P RLPP+T+PP
Sbjct: 541 VDPAISRDLGAPSLKKCPGGFSQHPALISDGCQVSYCVKSGLFTGGSLPPARLPPFTRPP 600

Query: 598 LMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGI 657
           LMSQ ATNTVIVTNSE ARSWIKD QT+QW+LGEP+ELRRAM VIHGD  G+SGG AAG+
Sbjct: 601 LMSQAATNTVIVTNSENARSWIKDSQTHQWRLGEPIELRRAMNVIHGDGGGLSGGAAAGV 660

Query: 658 TLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 713
           T+GVT  L +VITLAIYGTRK+KKK YQ IEE++SLV   A        E+  SPA
Sbjct: 661 TVGVTTILAVVITLAIYGTRKFKKKAYQAIEERQSLVPGTAATGDTTYQEQGQSPA 716


>UniRef50_Q7SXE0 Macrophage expressed 1 n=10 Tax=Clupeocephala RepID=Q7SXE0_DANRE
          Length = 718

 Score =  669 bits (1725), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 321/679 (47%), Positives = 449/679 (66%), Gaps = 29/679 (4%)

Query: 30  GFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQ 89
           G ++C+    L  LEVLPGGGWDNLRN+DMGRVM+L+Y+ C+TTEDG Y+IPDEV+ IPQ
Sbjct: 29  GLRLCRKNSSLTALEVLPGGGWDNLRNIDMGRVMNLSYSQCQTTEDGVYLIPDEVFVIPQ 88

Query: 90  KESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTR 149
           K S +E NSE++ SW+  +S+TS S+N +++ FS +N KFSTE QRMKT QVK+ +VT R
Sbjct: 89  KVSGVETNSEIIMSWLEQKSSTSSSVNADVSFFSVLNAKFSTENQRMKTHQVKEGSVTAR 148

Query: 150 VQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSV 209
           VQVRN +YTVK  P   L   F K   +I D +E NQT+ A YL+E L+L+YGTHVITSV
Sbjct: 149 VQVRNHLYTVKAYPDFTLDSRFAKQAEEIADAIENNQTRHANYLSEKLVLDYGTHVITSV 208

Query: 210 DAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSN 269
           DAGA LVQED+++ S++ ++Q+ +++V+ASAG  F + V F +  +    +S +  Y  N
Sbjct: 209 DAGATLVQEDYLKMSYISNSQSDKSSVSASAGANFFDKVKFDIGGNTSQGSSQSSSYQGN 268

Query: 270 RTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKK 329
            T S +QS GG  FYPGITL+ WQ+   N+L AIDR+GLPLH+F+ P   P LP P V K
Sbjct: 269 ITYSLIQSHGGALFYPGITLQKWQQSTLNNLAAIDRSGLPLHYFLNPSTFPDLPTPTVNK 328

Query: 330 LSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELS 389
           L+ TV  A   YY  NT PGC NVDSPNFNFQAN+DD SC+  +TN +FGG+YQ+CT L+
Sbjct: 329 LASTVRKAAERYYKVNTIPGCVNVDSPNFNFQANVDDASCEGPITNLSFGGIYQKCTPLT 388

Query: 390 --GDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT------LKIF 441
             G+++C    QKN  TG +SCP  Y+   L S+  E+G++  EC   C       L   
Sbjct: 389 PDGNIICDETAQKNPATGGYSCPQHYNTTLLHSEVVEKGFNHYECHTHCHSCGFLGLSTC 448

Query: 442 CKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPL 501
           C   C D + V +A+    WC +  + P+NSG LFGG+F     NP+T + SCP  Y   
Sbjct: 449 CDKTCGDSYHVRRAKLETLWCSSTHKTPENSGYLFGGLFGPGIQNPLTKSSSCPPSYFTQ 508

Query: 502 NLFES-LKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQ 560
               + + +C+S DYE+G +FSVPF GFFSC  GNPL N  +          +CP  FSQ
Sbjct: 509 RFLSNGMMICMSNDYEIGTRFSVPFAGFFSCQSGNPLSNGQS----------RCPPQFSQ 558

Query: 561 HLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIK 620
           HLA ISDGCQV YCV++G+F+GG L PVRLPP+T+PP++  +ATNTV V  +E  RSW++
Sbjct: 559 HLAAISDGCQVLYCVQSGVFSGGHLKPVRLPPFTRPPVVGMIATNTVAVM-TEGERSWVR 617

Query: 621 DPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYK 680
             +T  W+L +P ++++  +++  D++ MSGG+ AG+ +G+ + + +V+   +   ++  
Sbjct: 618 VGETKMWRLAKPGDIKQMQSIL--DASEMSGGKKAGVAIGIIVLVALVVAGTVVIMKRRN 675

Query: 681 K-------KEYQEIEEQES 692
           +       + Y+EI E+ +
Sbjct: 676 RFSSLKLNRGYEEISEERN 694


>UniRef50_UPI0000EBD8A9 PREDICTED: similar to macrophage expressed gene 1 n=1 Tax=Bos
           taurus RepID=UPI0000EBD8A9
          Length = 753

 Score =  506 bits (1304), Expect = e-141,   Method: Compositional matrix adjust.
 Identities = 267/714 (37%), Positives = 397/714 (55%), Gaps = 30/714 (4%)

Query: 25  ETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEV 84
           + G  GFQ CK  L + VL  LPG GWDNLRN+++G V+   Y+ C TTEDG+Y+IPD +
Sbjct: 35  DGGPWGFQGCKQQLNVSVLGALPGAGWDNLRNLELGLVLGRAYSQCLTTEDGEYLIPDGM 94

Query: 85  YTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQ 144
             +P++E+ ++  +++++SW+NY    + S+N E +  S +NGKFS E Q ++   ++ Q
Sbjct: 95  LAVPRRETVVQTRADLMDSWVNYTDAWAASVNAEFSFLSFLNGKFSAECQNVRRYSLQYQ 154

Query: 145 AVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTH 204
            +TTRVQ R+ IY+V+   T +    F + L+ + D LE NQT+ A YLAE+L+  YGTH
Sbjct: 155 TITTRVQRRHSIYSVRVRGTPDFHPDFRQRLLTLSDHLENNQTREAEYLAEMLVFAYGTH 214

Query: 205 VITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTK 264
           V+T V+ GA LVQED V    + +    +  VT +A + F   V       +  ++ L +
Sbjct: 215 VLTEVEVGATLVQEDQVSRELVGNEDKDRLNVTFAASVLFDRKVGVGDAVSWDKESQLVQ 274

Query: 265 DYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPG 324
            Y      S++ S GG PFY G+TL+ WQ+G+ N LVAI R+GLPL   ++P+ LP LP 
Sbjct: 275 AYQRGTVASKIHSRGGPPFYEGLTLQKWQEGVANRLVAIGRSGLPLPALLQPEALPELPA 334

Query: 325 PLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSC-DAKVTNFTFGGVYQ 383
           P V+++   V  A+  YY  N HPGC    +PNF+  AN+DD SC D +  NF+FGGV+Q
Sbjct: 335 PAVRRVEAAVSRAIGRYYEVNMHPGCVKRGAPNFDPLANVDDGSCTDGQHANFSFGGVFQ 394

Query: 384 ECTELS---GDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT--L 438
           EC  ++   G  LC+     N LTG  SCP  Y+   L S+         +C  +C    
Sbjct: 395 ECEAITGPEGGRLCKPYTILNPLTGQTSCPANYTASLLSSEVKVWSERSYQCWPQCQSCW 454

Query: 439 KIF--CKTVCEDVFRVAKAEFRAYWCVAAGQVPDNS-GLLFGGVFTDKTINPMTNAQSCP 495
            IF  C  +C ++         A WC  +G  P  + GLLFGG+++    NP T AQ+CP
Sbjct: 455 LIFTCCHRMCGNLEIQRVVRVNASWCAPSGATPTAAPGLLFGGLYSPGRPNPRTGAQACP 514

Query: 496 AGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLV------NSDTAKDVRAP 549
           + + PL L   LKVCVS D+ELG   +VPFGGFFSC +GNPL        S+  K+V   
Sbjct: 515 SSFFPLTLLGDLKVCVSSDWELGVAHAVPFGGFFSCQVGNPLAAQARGQGSEFLKEVFNL 574

Query: 550 SLK-----KCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP--LMSQV 602
           S+       CP G+SQH A +S GCQ+ YC++AG       L +RLPP+   P  L +  
Sbjct: 575 SVTMDHPMTCPAGYSQHPAYLSSGCQILYCLRAGFLLNPQQLMIRLPPFAARPSLLGNSS 634

Query: 603 ATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVT 662
                ++ ++   R+W+K   +++W+  +  +   A  +     +  S G   G  LG  
Sbjct: 635 GLGVSVLVDASGQRAWVKLQGSSRWRQADIHDPSVAAQLRDQGGSQPSAGAVVGACLGAV 694

Query: 663 IALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLN---GEEDPSPA 713
           + +  +     +G R+Y+K+ Y+ + E     G LA + TV       E P+P+
Sbjct: 695 LGVVALALGVTWGFRRYQKRGYRRLPE-----GILAEEQTVYGTAETAESPAPS 743


>UniRef50_UPI0000F2D8B8 PREDICTED: similar to Macrophage expressed gene 1 n=1
           Tax=Monodelphis domestica RepID=UPI0000F2D8B8
          Length = 1065

 Score =  495 bits (1274), Expect = e-138,   Method: Compositional matrix adjust.
 Identities = 245/567 (43%), Positives = 352/567 (62%), Gaps = 19/567 (3%)

Query: 67  YTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVN 126
           Y+ C+ TED +Y+IPD+V+ +P++ES LE +SE++  W  Y    SL+IN E +  S +N
Sbjct: 153 YSLCRVTEDREYLIPDQVHVVPRRESMLETHSEIIRDWRTYTDAFSLTINAEASFLSILN 212

Query: 127 GKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQ 186
           GKFS   QR K   V DQ +TTRVQ R  IY++   P   L+  F + L+ I + LE N+
Sbjct: 213 GKFSASSQRSKVHSVYDQTITTRVQARQHIYSLAAQPPWVLAEAFRQQLLHISEHLENNR 272

Query: 187 TKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLN 246
           ++ A+Y AELL+L YGTHV+T V+AGA+L+QED V+ + L +N   +  + ASA   F +
Sbjct: 273 SQQASYQAELLVLAYGTHVLTEVEAGASLMQEDQVKRALLDENSTKKVGIAASASAIFFS 332

Query: 247 IVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRA 306
            +          +     +Y+ N  +S++Q+ GG PFYPGITL+ WQ+ I N LVAI R+
Sbjct: 333 RIQLGANLTGQVRNQQQWEYVKNTVSSKIQNHGGEPFYPGITLQKWQQSIPNRLVAIGRS 392

Query: 307 GLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDD 366
           GLPL FFI P+ LP L  P V++L+ TV+ A++ YY  NT+PGC    + NFNFQAN+DD
Sbjct: 393 GLPLPFFITPEALPELQVPSVRRLALTVQKAIQQYYAVNTYPGCLQPKASNFNFQANVDD 452

Query: 367 DSCDAKVTNFTFGGVYQECTELSG---DVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTH 423
            SC+    +FTFGGV+Q+C  +SG   + LCQ     N LTG  SCP  YS + L S+  
Sbjct: 453 GSCEKAKHHFTFGGVFQKCQAVSGKGAETLCQPYRTANPLTGAASCPKNYSALLLNSELR 512

Query: 424 EEGYSRLECKKKCT----LKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVP-DNSGLLFGG 478
                ++EC+K+C+    L   CKTVC +    +     AYWC  AG       G LFGG
Sbjct: 513 SSNVPQMECRKQCSSCYWLFQCCKTVCGNREHPSVVSLSAYWCSPAGSPALSKPGFLFGG 572

Query: 479 VFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLV 538
           ++T+   NP+T AQ+CP  + PL LFE LKVCVS ++E+G   ++PFGGFFSC +GNPL 
Sbjct: 573 LYTNTQRNPLTKAQTCPHFFYPLVLFEDLKVCVSGNHEMGKSSAIPFGGFFSCRVGNPLA 632

Query: 539 ------NSDTAKDV---RAPSL--KKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLP 587
                 +    K+V    +P++   KCP G+SQH A +S+GCQ+ YC++AG      L+P
Sbjct: 633 GFLQGQSPGMLKEVFYRDSPTVYPMKCPPGYSQHQAYLSEGCQILYCLQAGALFAQQLVP 692

Query: 588 VRLPPYTKPPLMSQVATNTVIVTNSET 614
           + LPP+ +PPL+++  T+   + +S+ 
Sbjct: 693 IHLPPFIRPPLLNESYTDVDALVDSDA 719


>UniRef50_Q80VB7 Mpeg1 protein (Fragment) n=1 Tax=Mus musculus RepID=Q80VB7_MOUSE
          Length = 232

 Score =  480 bits (1236), Expect = e-134,   Method: Compositional matrix adjust.
 Identities = 231/232 (99%), Positives = 232/232 (100%)

Query: 482 DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD 541
           DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD
Sbjct: 1   DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD 60

Query: 542 TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ 601
           TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ
Sbjct: 61  TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ 120

Query: 602 VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV 661
           VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV
Sbjct: 121 VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV 180

Query: 662 TIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 713
           TIALG+VITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA
Sbjct: 181 TIALGVVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 232


>UniRef50_UPI0001796D85 PREDICTED: similar to Macrophage-expressed gene 1 protein precursor
           (Macrophage gene 1 protein) (Mpg-1) n=1 Tax=Equus
           caballus RepID=UPI0001796D85
          Length = 687

 Score =  470 bits (1209), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 264/684 (38%), Positives = 380/684 (55%), Gaps = 56/684 (8%)

Query: 23  LGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPD 82
           +G+ G  GFQ CK  L +PVL  LPGGGWDNLRNV++  V+   Y+ C TTE G+Y+I D
Sbjct: 19  MGDPGAPGFQGCKQTLNVPVLGALPGGGWDNLRNVELELVLRRYYSQCLTTEAGEYLIQD 78

Query: 83  EVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVK 142
           +++ +PQ+ES +E   E                     L + +NGK S + Q +K   ++
Sbjct: 79  QLHVVPQRESFVETRGE---------------------LINDLNGKSSIDCQNVKKYNLE 117

Query: 143 DQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYG 202
            Q VT RVQVR+ IY+VK     +    F + L+ + D LE +Q + A YLAE+L+L YG
Sbjct: 118 YQMVTARVQVRHSIYSVKAPEIPDFQPTFRQHLLALSDHLENDQIREAEYLAEMLVLWYG 177

Query: 203 THVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSL 262
           THV+T V+AGA LVQED VR   +      +N VT++A   F ++VNF     + +Q+ L
Sbjct: 178 THVLTDVEAGATLVQEDQVRRELVDSQAGERNNVTSTASAVFFHMVNFGDAASWQAQSQL 237

Query: 263 TKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL 322
            +DY+ N   S+++S GGVPFYPGITL+ WQ+GI+N LVAI R+ LPL   ++P+ LP L
Sbjct: 238 FQDYVRNTVASKMRSQGGVPFYPGITLQKWQEGISNRLVAIGRSELPLPALLQPEALPEL 297

Query: 323 PGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVY 382
           P P V++++  V  A+  YY  N  PGC    +P FN QAN++D SC    +NF+FGGV+
Sbjct: 298 PAPTVQRVAAAVRRAIHRYYAVNALPGCLRRGAPAFNPQANLEDGSCGGGRSNFSFGGVF 357

Query: 383 QECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKC-TLKIF 441
           QEC  +SG                   P  Y+   L S+       R EC+++C    +F
Sbjct: 358 QECEAVSGQT-----------------PTSYTASALHSELKTWSEPRPECQQQCRKCWLF 400

Query: 442 ---CKTVCEDVFRVAKAEFRAYWCV-AAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAG 497
              C+TVC    + +     A WCV +   +P  SG LFGG+++    NP T AQ+CP+ 
Sbjct: 401 FQCCQTVCATHEQRSVVRLAASWCVPSQASLPATSGFLFGGLYSPGNSNPFTKAQACPSY 460

Query: 498 YIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLV-----------NSDTAKDV 546
           +  L LF  LKVCVS D ELG   +VPFGGFFSC +GNPLV                +D 
Sbjct: 461 FYALTLFGDLKVCVSSDLELGAAQAVPFGGFFSCQVGNPLVGLLKGQSPGLLQEMFCQDS 520

Query: 547 RAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLM--SQVAT 604
                 KCP G+SQH A +S+GCQ+  C++AG   G     VR+PP+   P +  S  A 
Sbjct: 521 PTDHPMKCPAGYSQHQAYLSNGCQIFCCLRAGALLGQQQAAVRMPPFLPRPPLLNSSSAH 580

Query: 605 NTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIA 664
           +  ++ +S   R W++   ++ W+     +L  A  ++    +  S G  AG  +G  +A
Sbjct: 581 SLSVLVDSTGQRVWVRLQGSDCWQQANINDLSLAAKLLSQAGSKPSIGAIAGSWVGTLVA 640

Query: 665 LGIVITLAIYGTRKYKKKEYQEIE 688
           + +V     YG R+YKK  Y+ ++
Sbjct: 641 VVVVTLGISYGFRRYKKGGYKRLQ 664


>UniRef50_Q6RYF9 Macrophage expressed protein n=5 Tax=Eumetazoa RepID=Q6RYF9_HALCO
          Length = 730

 Score =  460 bits (1184), Expect = e-128,   Method: Compositional matrix adjust.
 Identities = 253/621 (40%), Positives = 359/621 (57%), Gaps = 36/621 (5%)

Query: 39  KLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNS 98
           KL   EVLPG GWDNLRNVD G V+   Y+ C+TTEDG+Y+IPD V TIP K S L + +
Sbjct: 42  KLERFEVLPGQGWDNLRNVDAGLVVVYNYSRCRTTEDGRYLIPDTVNTIPLKASKLNVYA 101

Query: 99  EVLESWMNYQSTTSLSINTELAL---FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNR 155
           E++  W +Y STT+  +N +  L     +V+GKFS+ ++ +K+ Q+ D++ TTRVQ+R  
Sbjct: 102 ELISHWSSYTSTTAHGVNVDAGLKYDSVQVSGKFSSGYESVKSKQIGDKSYTTRVQLRYV 161

Query: 156 IYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAAL 215
            Y+ K  P + L   F   L+ I   L+ N+T  A Y +ELL+ ++GTHV+TSVDAGAAL
Sbjct: 162 RYSAKLQPDASLHPTFKTRLLSIAGSLQLNKTDQARYDSELLVRDFGTHVVTSVDAGAAL 221

Query: 216 VQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTS--LTKDYLSNRTNS 273
           VQED V S F+   + ++N +TA A  +   I  F ++  Y S TS  + K Y  +R++S
Sbjct: 222 VQEDQVSSEFVNSRKFTKNQITAGASASLFGI--FSIDVSYHSSTSNEVKKAYEQSRSSS 279

Query: 274 RVQSFGGVPFYPG-ITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSK 332
           ++ + GG  F     T   W   + + LVA+DR+G PL F I    LP LP  ++ +L  
Sbjct: 280 QIDTLGGPMFKASNFTANDWTNEVDHELVAVDRSGDPLFFLINSASLPELPNSVLYQLQN 339

Query: 333 TVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDV 392
            VE  + HYY FNT+ GCT +DSPNF+  AN+DD +C +  TN TFGGVYQ C+  SG  
Sbjct: 340 LVEETILHYYEFNTYRGCTELDSPNFSPAANLDDGTCKSPYTNLTFGGVYQTCSMSSGSN 399

Query: 393 ---LCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDV 449
              LC  L+Q N  TG  +CP GY  V L +    +  S   C   C L   C   C D 
Sbjct: 400 NGDLCSGLDQVNPKTGGHTCPDGYESVELHTGRLSDSKSVHSC-HSCWLFFKC---CHDN 455

Query: 450 FRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKV 509
           +  ++A +  +WC A G V  +SG LFGG++T +  NP+T  ++CP  +    L + L +
Sbjct: 456 YYHSEATYIMHWCAATGPVSQDSGYLFGGLYTSQLNNPLTQGKTCPVNFYTRTLGKDLHI 515

Query: 510 CVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAK---DVRA--PSL-----------KK 553
           C+S DYELG K+S+PFGGF SC  GNPL  +   K   D+ +  PSL           K 
Sbjct: 516 CISDDYELGMKYSMPFGGFISCTTGNPLAMNPKPKSKGDMNSALPSLHSFFQGSKTWPKH 575

Query: 554 CPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSE 613
           CP G+SQHLA +  GC+++YC+ AG  +   L  +R PP+   PL+     N V+     
Sbjct: 576 CPKGYSQHLAYVDQGCEINYCLLAGSLSEVGLPKIRRPPFQTAPLLLPSTENHVVF--DP 633

Query: 614 TARSWIKDPQTNQW---KLGE 631
              +W K+ +  Q+   ++GE
Sbjct: 634 VTLTWRKNQEAMQFISARVGE 654


>UniRef50_A7SEK6 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
           RepID=A7SEK6_NEMVE
          Length = 583

 Score =  456 bits (1172), Expect = e-126,   Method: Compositional matrix adjust.
 Identities = 245/596 (41%), Positives = 339/596 (56%), Gaps = 25/596 (4%)

Query: 44  EVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLES 103
           EVLPGGGWDNLRN+ MG V  + Y+ C++++DG++++PD V+  P K+S +   +E  + 
Sbjct: 1   EVLPGGGWDNLRNLHMGAVSAMNYSLCRSSDDGKFLVPDNVFLYPVKKSKVNTFAEFYDH 60

Query: 104 WMNYQSTTSLSINTE---LALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVK 160
           W NY STT+ SIN E      F  V+G FS+E++ +K  QV+D+ VTTRVQ+R+  YT K
Sbjct: 61  WNNYSSTTTKSINAEAKASFGFGSVSGSFSSEYESVKKHQVEDKTVTTRVQLRHVFYTAK 120

Query: 161 TTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDH 220
             P S L   F   L++I   L+ N T  A++LA++L+ ++GTH ++SVDAGA L + DH
Sbjct: 121 LQPDSPLQPAFKDRLLEIASHLQHNNTAYASFLAQVLVRDFGTHYVSSVDAGAVLAKVDH 180

Query: 221 VRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG 280
           +   F+ D+   ++ +TASA  +F +           + T    +Y      S   ++GG
Sbjct: 181 LTKKFVADSNEDKSKITASASASFFHFFGASGSYSKSTDTKTLDEYTKATVYSTTYTYGG 240

Query: 281 VPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRH 340
            PF    T+  W+  + + LVA+DR+G PLH+ I P  LP L      +L+  V+ A++ 
Sbjct: 241 PPFRVNFTINEWEDKMLDELVAVDRSGDPLHYTITPGSLPELCEQATFQLAAVVKNAIKQ 300

Query: 341 YYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECT---ELSGDVLCQNL 397
           YY  NT  GCT +DSPNF+FQANMDD SC +   N+TFGGVYQ C      S D  C  L
Sbjct: 301 YYIHNTIKGCTKMDSPNFSFQANMDDGSCQSPTNNYTFGGVYQTCQTDGSPSSDP-CAPL 359

Query: 398 EQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEF 457
            QKN LT D++C PGY PV +      +G +   C K C         C    +     F
Sbjct: 360 AQKNPLTADYTCTPGYEPVLV-----HQGRTPQSCHKDCHRVWLFFKRCS--VQCGFGSF 412

Query: 458 RAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYEL 517
             YWCVA   VP NSG LFGG+++D   NP+T   SCP  +  L    ++KVCVS DYEL
Sbjct: 413 STYWCVAKSAVPANSGYLFGGLYSDVLKNPLTQDHSCPLKFYALKFGATMKVCVSDDYEL 472

Query: 518 GFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSL--KKCPGGFSQHLAVISDGCQVSYCV 575
           G++ S+PFGGFFSC  GNPL         + P    K CP GFSQHL  I   C++ YCV
Sbjct: 473 GYQQSLPFGGFFSCNAGNPLA-------FKKPPTGDKGCPTGFSQHLGAIEANCEIQYCV 525

Query: 576 KAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDP-QTNQWKLG 630
           K+ +F    L  VR PPY  PP +   +   ++V N +T + W K      QW L 
Sbjct: 526 KSNVFNLQGLPIVRRPPYLSPPAVYNYSVPMLLV-NEDTGQIWFKRAGNMPQWLLA 580


>UniRef50_B3F732 Macrophage expressed protein 1-like protein n=1 Tax=Crassostrea
           gigas RepID=B3F732_CRAGI
          Length = 621

 Score =  442 bits (1138), Expect = e-122,   Method: Compositional matrix adjust.
 Identities = 245/621 (39%), Positives = 350/621 (56%), Gaps = 41/621 (6%)

Query: 43  LEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLE 102
            EVLPG GWDNL+N D G ++   Y+ C+TT+DGQY+IPD VYT+P K S LE+  E+ +
Sbjct: 8   FEVLPGLGWDNLQNKDAGMLVQYNYSECRTTDDGQYLIPDGVYTVPLKSSKLEVFGELFQ 67

Query: 103 SWMNYQSTTSLSINTELALF---SRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTV 159
            W N+ STTS S+N E  L      ++GK+S E   ++  Q+ D++VTTRVQ R   Y+ 
Sbjct: 68  HWNNFTSTTSSSVNVEAGLHLGSFGISGKYSHESDSVRKHQIMDRSVTTRVQARYARYSA 127

Query: 160 KTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQED 219
              P + L+  F   L +I   ++ N+T MA Y ++LL+ +YGTHVI+SV    + +   
Sbjct: 128 LLQPDTPLNPAFRDRLRNIAYYIQTNKTNMARYQSQLLVRDYGTHVISSVQRVPSSLSLT 187

Query: 220 HVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFG 279
            +R   +      +  V           V    E  + + T +   YL NRT+S + + G
Sbjct: 188 RLRRRSVTVTAWDRRQVVGRGQCLVYERVYVGAEYKHSTSTEVIDQYLGNRTHSVINAIG 247

Query: 280 GVPFYPG-ITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAV 338
           G  F P   TL  W  G++  LVA+D++G P++  I    LP LP  ++  L +TV++AV
Sbjct: 248 GPVFQPNNFTLNQWASGLSGDLVAVDKSGYPIYELISAQTLPELPPSILFPLVQTVKSAV 307

Query: 339 RHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDV---LCQ 395
             YY FN + GCTN+DSPNF+F AN+DD +C++  TN+TFGGVYQ+C + SG +   LC 
Sbjct: 308 EEYYKFNIYRGCTNLDSPNFSFIANVDDGTCESPETNYTFGGVYQQCKQ-SGQLSQNLCN 366

Query: 396 NLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKA 455
            L QKN LTG  SCP GY  V L   T     SR  C     L +  +  C++      A
Sbjct: 367 GLVQKNPLTGAQSCPSGYESVLLNEGTRSATESRRRCHHCGFLGL--RHCCDNYNVYGSA 424

Query: 456 EFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDY 515
           +++++WCVA G V   SG  FGG++T+K  NP+T ++ CP  + PL L   ++VCVS DY
Sbjct: 425 KYQSFWCVAQGHVDQQSGFQFGGIYTNKIDNPLTQSRGCPLYFYPLKLGLGMQVCVSDDY 484

Query: 516 ELGFKFSVPFGGFFSCIMGNPL-VNSDTAKDVRAPSL---------------KKCPGGFS 559
           ELGF++SVPF G FSC+ GNPL V+ DT+   + P +               + CP G+S
Sbjct: 485 ELGFRYSVPFAGLFSCMTGNPLAVHQDTS--FKNPDMLHSLSSYLKASNNWPRGCPTGYS 542

Query: 560 QHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP----LMSQVATNTVIVTNSETA 615
            HLA I + C+++YCVKA  F+   L PVR PP+   P    + S ++   +I T  ET 
Sbjct: 543 MHLATIENSCEINYCVKANAFSDKGLPPVRRPPFMDLPGDAYVDSGISEEYMISTGGET- 601

Query: 616 RSWIKDPQTNQWKLGEPLELR 636
             W          LG P + R
Sbjct: 602 --WTD------LTLGGPAQFR 614


>UniRef50_Q4W1E5 Macrophage expressed protein n=1 Tax=Suberites domuncula
           RepID=Q4W1E5_SUBDO
          Length = 676

 Score =  380 bits (976), Expect = e-103,   Method: Compositional matrix adjust.
 Identities = 209/585 (35%), Positives = 319/585 (54%), Gaps = 68/585 (11%)

Query: 39  KLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNS 98
           KL +L+V+PG GWDNLRN + G +   +Y+ CK T D +Y+IPDE + IP K S ++  +
Sbjct: 70  KLNILQVVPGIGWDNLRNSETGILTSFSYSQCKVTYDRRYLIPDETFAIPIKTSTIDYQA 129

Query: 99  EVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYT 158
           E+ + W  Y+S TS SIN     F ++ G                               
Sbjct: 130 ELFDHWDAYKSVTSRSINAGFDFFGKIGG------------------------------- 158

Query: 159 VKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQE 218
                             +I   L+ N T+ A Y A++LI +YGTH ITS+DAGA L++E
Sbjct: 159 ------------------EILSLLKSNDTESADYAAQILIRDYGTHCITSIDAGAVLIKE 200

Query: 219 DHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQT--SLTKDYLSNRTNSRVQ 276
           D+++S+ + + +   ++++ +AG+ F +++  +    + S +  S  K Y  NRT+SR+ 
Sbjct: 201 DNLKSTIMSNYKGRADSLSTAAGVEFYDMLKLRASAGFSSYSGDSDLKAYRQNRTSSRLY 260

Query: 277 SFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFF-----IKPDKLPGLPGPLVKKLS 331
           ++GG P+  G+ L  W+  + N+LVA DR+G P H       +KP+        L+++L 
Sbjct: 261 TYGGPPYKLGMNLSRWENDLMNNLVATDRSGKPSHSLSTTQSLKPEVTTSQEVFLLRRL- 319

Query: 332 KTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDS-CDAKVTNFTFGGVYQECTELSG 390
             V++AV  YY +NTH GC N  +PN + Q N      C     N+TFGGV+Q C   +G
Sbjct: 320 --VKSAVSQYYHYNTHTGCKNPKAPNLDHQTNNGAPGVCKEPSANYTFGGVFQSCRS-NG 376

Query: 391 DVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLEC--KKKCTLKIF-CKTV-- 445
           + +C  L QKN LTG +SCP  +  + L   T      R  C  K+KCT  +F C  V  
Sbjct: 377 NDICGKLLQKNPLTGGYSCPKNFKALLLQLGTERSHKMRRVCVWKRKCTFFVFNCHDVDD 436

Query: 446 CEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFE 505
           C  V  V  A ++ YWC    + P   G +FGG++++   NP+T + SCP  ++PL + E
Sbjct: 437 CTFVPSVEIASYQTYWCAPNKKNPPKFGYMFGGIYSNDIQNPITRSCSCPTHFLPLRMGE 496

Query: 506 SLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPS--LKKCPGGFSQHLA 563
              VCVS DYELG +FS+PFGGFFSC+ GN L  + +++ +  P     +CPGGF+QHLA
Sbjct: 497 RATVCVSEDYELGHQFSLPFGGFFSCVSGNVLAGNGSSEFLNNPKDWPMRCPGGFTQHLA 556

Query: 564 VISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVI 608
           +   GC+V++CVKAG     S L + LPP+   P + + +T+ + 
Sbjct: 557 LTEKGCRVNFCVKAGSLLRASDLELVLPPFDPKPTLRKNSTSDLF 601


>UniRef50_C4Q3P0 Expressed protein n=2 Tax=Schistosoma RepID=C4Q3P0_SCHMA
          Length = 1103

 Score =  276 bits (705), Expect = 3e-72,   Method: Compositional matrix adjust.
 Identities = 185/527 (35%), Positives = 273/527 (51%), Gaps = 62/527 (11%)

Query: 43  LEVLPGGGWDNLRNVDMGRVMDL-TYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVL 101
           L VLPG GWDNL N + G ++D+  Y+ C+ + DG+++IPDE+   P K S ++++SEV 
Sbjct: 339 LSVLPGFGWDNLVNRERGPIIDVEKYSLCRRSVDGKFLIPDEITVQPIKNSEIKLSSEVY 398

Query: 102 ESWMNYQSTTSLSINT----ELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRV------- 150
           ES    +S  + SIN+    E + F R+NG FS++ + ++   VK   VT          
Sbjct: 399 ESISQCRSLVAYSINSAVGGEYSYF-RINGDFSSDKETLREKLVKHGNVTMETIELFNNG 457

Query: 151 ----QVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVI 206
                +RN +  V       LS G                   A YLA+L++ ++GTH I
Sbjct: 458 LIGNTLRNSLGIVTNDNFKSLSQGMN-----------------AFYLADLVVRDFGTHCI 500

Query: 207 TSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDY 266
            SV AG  L + D + ++ L   +  +  + ASA I+F N+ N K+        SL ++Y
Sbjct: 501 NSVYAGGVLAKIDTLDTNSLNTKKEDRWHLGASATISFANLFNVKLGGSANVNDSLIQNY 560

Query: 267 LSNRTNSRVQSFGG-VPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGP 325
            S  T S++ ++GG + +   + L  W+ G+ N LVAIDR+G P++  I    LP L   
Sbjct: 561 ESKITYSQILTYGGPIIYMSNVNLSLWESGLDNQLVAIDRSGQPIYELITDRSLPELSSH 620

Query: 326 LVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCD---AKVTNFTF--GG 380
           ++ +L  T+++AV  YY  NT  GC N  S  ++ +AN+    CD    ++TN T   GG
Sbjct: 621 MIVRLVATIKSAVERYYKANTVVGCMNPLSVFYDNEANVASPECDLQSKQITNTTLYLGG 680

Query: 381 VYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLK- 439
           VYQ+CT    D LC      N LTGD  C  GY  + LL Q   + YS   C +K   K 
Sbjct: 681 VYQKCT--GPDDLCLGETIPNPLTGDLFCSQGYVSIQLLPQQVRKCYSV--CDEKSWFKN 736

Query: 440 IFCKTVCEDVFRVAKAEFRAYWCVAAGQVPD---------NSGLLFGGVFTDKTINPMTN 490
             C T C        A   +YWC     +           +SG LFGG++TDK +N +T 
Sbjct: 737 PECTTQC--------AITESYWCSRDPSLSSSSSNILDNSDSGYLFGGLYTDKEVNSLTK 788

Query: 491 AQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPL 537
             +CP  Y P+ L   +++C+S D ELG K+S+PFGGF+SC  GNPL
Sbjct: 789 QYNCPQYYWPITLGRRMRICLSTDRELGGKYSLPFGGFYSCYSGNPL 835



 Score = 52.0 bits (123), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 11/87 (12%)

Query: 537 LVNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKP 596
            V +D ++   A   KKCP G++ HLA + D CQV+YCV+A          ++ PP+  P
Sbjct: 918 FVQNDFSQLFAALWPKKCPVGYTAHLAAMEDICQVNYCVQANFLKEQVRRQLKRPPFVLP 977

Query: 597 PLMSQVATNTVIVTNSETARSWIKDPQ 623
                      I TN E   S+  DP 
Sbjct: 978 -----------IYTNEEKLPSFSNDPH 993


>UniRef50_Q2XSC0 Macrophage expressed protein (Fragment) n=1 Tax=Mytilus edulis
           RepID=Q2XSC0_MYTED
          Length = 338

 Score =  230 bits (587), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 129/345 (37%), Positives = 193/345 (55%), Gaps = 17/345 (4%)

Query: 210 DAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSN 269
           D+GA++V+ DHV+   L D+   +  ++A+AG        F V+        +   YL++
Sbjct: 3   DSGASIVKVDHVKRELLQDDTIDKFQISAAAGAEL-----FGVQVGITIPAEVMTKYLAS 57

Query: 270 RTNSRVQSFGGVPFYP-GITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK 328
           +T+S + + GG  + P   T+  W K I  +LV++DR+G PLHF I     P L   +V 
Sbjct: 58  KTHSSILTHGGPLYLPVNFTINDWVKQIDQNLVSVDRSGDPLHFIINEYMFPELSISIVT 117

Query: 329 KLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKV--TNFTFGGVYQECT 386
             +  VE+A++ YY  NTH GCTN DSPN+N+ AN+DD +C+  +  TN  FGGV+Q C 
Sbjct: 118 DTAAAVESAIKTYYKMNTHRGCTNRDSPNYNYLANVDDGTCEYNLNATNTNFGGVFQTC- 176

Query: 387 ELSGDV--LCQNLEQKNLLTGDFSCPPGYSPVHL-LSQTHEEGYSRLECKKKCTLKIFCK 443
            ++G++  +C     KN LTGDFSCP G+  V L L   ++E     E  + C+  +   
Sbjct: 177 NVTGNIDGICDTFLSKNPLTGDFSCPNGFIAVPLFLGHDNKE-----EVHRTCSKYMIFW 231

Query: 444 TVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNL 503
           + CE    +  A +++YWC   G      G LFGG++T +  N +T  QSCP  +  + +
Sbjct: 232 SHCETTSNLGTASYQSYWCCPQGGNQSFPGYLFGGLYTTQLPNVVTQHQSCPQYFTAIGI 291

Query: 504 FESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRA 548
            E LK+CVS D E GF++S+PFGGFFSC   N L  +  A    A
Sbjct: 292 AEDLKICVSDDIENGFQYSIPFGGFFSCQNDNLLAANQNATHCHA 336


>UniRef50_Q5BVJ5 SJCHGC08097 protein (Fragment) n=1 Tax=Schistosoma japonicum
           RepID=Q5BVJ5_SCHJA
          Length = 205

 Score = 85.9 bits (211), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 38/88 (43%), Positives = 54/88 (61%), Gaps = 8/88 (9%)

Query: 459 AYWCVAAGQVP--------DNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVC 510
           +YWC     +         D +G LFGG++TDK +N +T   +CP  Y P+ L   +++C
Sbjct: 28  SYWCSRDPSLSSSPKVLDIDENGYLFGGLYTDKEVNSLTKQYNCPQYYWPIALGRRMRIC 87

Query: 511 VSLDYELGFKFSVPFGGFFSCIMGNPLV 538
           +S D ELG K+S+PFGGF+SC  GNPL 
Sbjct: 88  LSSDRELGGKYSLPFGGFYSCFSGNPLT 115


>UniRef50_O76288 Apextrin n=4 Tax=Echinoida RepID=O76288_HELER
          Length = 491

 Score = 47.4 bits (111), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 51/212 (24%), Positives = 89/212 (41%), Gaps = 19/212 (8%)

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEV------YTIPQKESNLEMNSEVLESWMNYQSTTSLS 114
           R+ +LTY N KTT D +Y +PDEV       +   KE++    ++     +++Q     S
Sbjct: 67  RIFELTYDNGKTTNDNEYRVPDEVEFQQRSSSFTSKETDTFYGTKSYAKKLSHQVQADAS 126

Query: 115 INTELALFSRVNGKFSTEFQRMKT-LQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTK 173
           +    A+F+ V    S  ++ +      K    ++   ++N  +    T  +E   GF  
Sbjct: 127 VE---AVFASVKFSASHRYESISNDASTKGYVYSSEQTIQNFGHMRYLTSLAEHD-GFEI 182

Query: 174 A---LMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAAL-VQEDHVRSSFLLDN 229
           A    +D+CD      T  AT      +  +GT V+T  D G    +     RSSF+ D 
Sbjct: 183 AREFRIDVCDL----PTTYATNTYMEFLSKWGTSVVTEADVGVRTGINSREDRSSFVKDA 238

Query: 230 QNSQNTVTASAGIAFLNIVNFKVETDYISQTS 261
               +   +  G   +   +  V+ D  SQ++
Sbjct: 239 STDMSNSVSVEGNYKIFSASLSVDMDRFSQSA 270


>UniRef50_UPI0000E49992 PREDICTED: similar to apextrin n=17 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E49992
          Length = 570

 Score = 47.0 bits (110), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 54/200 (27%), Positives = 83/200 (41%), Gaps = 22/200 (11%)

Query: 42  VLEVLPGGGWDNLRNVDMG-----RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEM 96
           +LE  P GG      VD G     R+ +L+Y   K + DG Y +PDEVY + +  +    
Sbjct: 43  ILEGNPEGGELGSGGVDPGLLVSRRIFELSYDESKVSSDGMYRVPDEVYFVSRDSAFTSS 102

Query: 97  NSEVLESWMNYQSTTSLSIN-------TELALFSRVNGKFSTEFQRMKTLQVKDQAVTTR 149
           +        +Y S  S  ++       T  +     + ++ T   RM +      A  T 
Sbjct: 103 SRTTFHGTESYASKLSAQVDVAGSYSGTFASAEFAASARYETISNRMASQGSVFFATQTI 162

Query: 150 VQVRN-RIYTVKTTPTS-ELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVIT 207
             + N R  T    P S  L+ GF   + D C     N    A Y+    + ++GTHV+T
Sbjct: 163 QNLGNARYLTELAQPNSYALNNGF---VSDACSL--PNSYNEADYMQ--FLESWGTHVVT 215

Query: 208 SVDAGAAL-VQEDHVRSSFL 226
            VD G  +    +  RSSF+
Sbjct: 216 EVDLGTRVGTNYEESRSSFV 235


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q2M385 Macrophage-expressed gene 1 protein n=18 Tax=Mam...  1107   0.0  
UniRef50_UPI0000EBD8A9 PREDICTED: similar to macrophage expresse...   959   0.0  
UniRef50_Q7SXE0 Macrophage expressed 1 n=10 Tax=Clupeocephala Re...   933   0.0  
UniRef50_UPI0001796D85 PREDICTED: similar to Macrophage-expresse...   849   0.0  
UniRef50_Q6RYF9 Macrophage expressed protein n=5 Tax=Eumetazoa R...   820   0.0  
UniRef50_UPI0000F2D8B8 PREDICTED: similar to Macrophage expresse...   801   0.0  
UniRef50_B3F732 Macrophage expressed protein 1-like protein n=1 ...   798   0.0  
UniRef50_A7SEK6 Predicted protein (Fragment) n=1 Tax=Nematostell...   794   0.0  
UniRef50_Q4W1E5 Macrophage expressed protein n=1 Tax=Suberites d...   692   0.0  
UniRef50_C4Q3P0 Expressed protein n=2 Tax=Schistosoma RepID=C4Q3...   575   e-162
UniRef50_Q2XSC0 Macrophage expressed protein (Fragment) n=1 Tax=...   456   e-126
UniRef50_Q80VB7 Mpeg1 protein (Fragment) n=1 Tax=Mus musculus Re...   383   e-104
UniRef50_Q5BVJ5 SJCHGC08097 protein (Fragment) n=1 Tax=Schistoso...   144   1e-32

Sequences not found previously or not previously below threshold:

UniRef50_Q23QV7 E1-E2 ATPase family protein n=4 Tax=Tetrahymena ...    70   3e-10
UniRef50_D2WL87 MAC/perforin-and kringle-domains-containing prot...    70   3e-10
UniRef50_A0T3F5 Apextrin n=1 Tax=Acropora millepora RepID=A0T3F5...    70   3e-10
UniRef50_Q23QV5 MAC/Perforin domain containing protein n=1 Tax=T...    68   1e-09
UniRef50_Q1CW76 Putative uncharacterized protein n=1 Tax=Myxococ...    65   1e-08
UniRef50_Q23QV6 MAC/Perforin domain containing protein n=2 Tax=T...    63   3e-08
UniRef50_O76288 Apextrin n=4 Tax=Echinoida RepID=O76288_HELER          60   4e-07
UniRef50_UPI0000E49992 PREDICTED: similar to apextrin n=17 Tax=S...    59   5e-07
UniRef50_B0R0K6 Novel protein n=10 Tax=Clupeocephala RepID=B0R0K...    57   3e-06
UniRef50_D0ZYB6 MAC/perforin domain protein n=1 Tax=Chlamydophil...    57   3e-06
UniRef50_P14222 Perforin-1 n=27 Tax=Mammalia RepID=PERF_HUMAN          56   5e-06
UniRef50_UPI00006A1994 UPI00006A1994 related cluster n=5 Tax=Xen...    55   1e-05
UniRef50_C4JX95 Predicted protein n=1 Tax=Uncinocarpus reesii 17...    55   1e-05
UniRef50_UPI00006CCD2A MAC/Perforin domain containing protein n=...    54   2e-05
UniRef50_Q9U0J9 MAC/Perforin, putative n=8 Tax=Plasmodium RepID=...    53   5e-05
UniRef50_UPI00006A16E1 Perforin 1 precursor (P1) (Lymphocyte por...    52   6e-05
UniRef50_UPI0000E48CEE PREDICTED: similar to apextrin n=1 Tax=St...    52   7e-05
UniRef50_C3PWZ7 Putative uncharacterized protein n=2 Tax=Bactero...    51   1e-04
UniRef50_B3L016 Sporozoite protein with MAC/Perforin domain n=1 ...    51   2e-04
UniRef50_Q23I78 MAC/Perforin domain containing protein n=2 Tax=T...    50   2e-04
UniRef50_Q254S3 Phospholipase D endonuclease n=13 Tax=Chlamydiac...    50   2e-04
UniRef50_A0BCZ0 Chromosome undetermined scaffold_10, whole genom...    50   3e-04
UniRef50_Q8I2S3 MAC/Perforin, putative n=9 Tax=Plasmodium RepID=...    50   4e-04
UniRef50_A7RF42 Predicted protein n=1 Tax=Nematostella vectensis...    50   4e-04
UniRef50_P07357 Complement component C8 alpha chain n=23 Tax=Amn...    49   6e-04
UniRef50_C0YM92 Putative uncharacterized protein n=1 Tax=Chryseo...    49   8e-04
UniRef50_B6Q8L9 Putative uncharacterized protein n=1 Tax=Penicil...    48   0.001
UniRef50_Q5TWT0 AGAP007256-PA n=4 Tax=Endopterygota RepID=Q5TWT0...    47   0.002
UniRef50_UPI000180CB36 PREDICTED: similar to complement componen...    47   0.003
UniRef50_B7FK63 Putative uncharacterized protein n=4 Tax=fabids ...    46   0.004
UniRef50_B2AER0 Predicted CDS Pa_5_1800 n=1 Tax=Podospora anseri...    46   0.004
UniRef50_UPI00005841B7 PREDICTED: similar to apextrin n=1 Tax=St...    46   0.006
UniRef50_Q4SUR7 Chromosome undetermined SCAF13844, whole genome ...    45   0.007
UniRef50_Q64VU4 Putative uncharacterized protein n=2 Tax=Bactero...    45   0.008
UniRef50_C3ZTX2 Putative uncharacterized protein n=4 Tax=Branchi...    44   0.028
UniRef50_Q2H1U9 Putative uncharacterized protein n=1 Tax=Chaetom...    42   0.056
UniRef50_A4QZP4 Predicted protein n=1 Tax=Magnaporthe grisea Rep...    42   0.058

>UniRef50_Q2M385 Macrophage-expressed gene 1 protein n=18 Tax=Mammalia
           RepID=MPEG1_HUMAN
          Length = 716

 Score = 1107 bits (2863), Expect = 0.0,   Method: Composition-based stats.
 Identities = 542/716 (75%), Positives = 621/716 (86%), Gaps = 3/716 (0%)

Query: 1   MNSFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMG 60
           MN+F A +L W   A A++ KP GE    G Q CKNALKLPVLEVLPGGGWDNLRNVDMG
Sbjct: 1   MNNFRATILFWAAAAWAKSGKPSGEMDEVGVQKCKNALKLPVLEVLPGGGWDNLRNVDMG 60

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA 120
           RVM+LTY+NC+TTEDGQYIIPDE++TIPQK+SNLEMNSE+LESW NYQS+TS SINTEL+
Sbjct: 61  RVMELTYSNCRTTEDGQYIIPDEIFTIPQKQSNLEMNSEILESWANYQSSTSYSINTELS 120

Query: 121 LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICD 180
           LFS+VNGKFSTEFQRMKTLQVKDQA+TTRVQVRN +YTVK  PT ELS GF K L+DI D
Sbjct: 121 LFSKVNGKFSTEFQRMKTLQVKDQAITTRVQVRNLVYTVKINPTLELSSGFRKELLDISD 180

Query: 181 QLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASA 240
           +LE NQT+MATYLAELL+LNYGTHV TSVDAGAAL+QEDH+R+SFL D+Q+S++ VTASA
Sbjct: 181 RLENNQTRMATYLAELLVLNYGTHVTTSVDAGAALIQEDHLRASFLQDSQSSRSAVTASA 240

Query: 241 GIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHL 300
           G+AF N VNFK E +Y SQ  LTK YLSNRTNSRVQS GGVPFYPGITL+ WQ+GITNHL
Sbjct: 241 GLAFQNTVNFKFEENYTSQNVLTKSYLSNRTNSRVQSIGGVPFYPGITLQAWQQGITNHL 300

Query: 301 VAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNF 360
           VAIDR+GLPLHFFI P+ LP LPGPLVKK+SKTVETAV+ YYTFNT+PGCT+++SPNFNF
Sbjct: 301 VAIDRSGLPLHFFINPNMLPDLPGPLVKKVSKTVETAVKRYYTFNTYPGCTDLNSPNFNF 360

Query: 361 QANMDDDSCDAKVTNFTFGGVYQECTELSGD---VLCQNLEQKNLLTGDFSCPPGYSPVH 417
           QAN DD SC+ K+TNF+FGGVYQECT+LSG+   +LCQ LEQKN LTGDFSCP GYSPVH
Sbjct: 361 QANTDDGSCEGKMTNFSFGGVYQECTQLSGNRDVLLCQKLEQKNPLTGDFSCPSGYSPVH 420

Query: 418 LLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFG 477
           LLSQ HEEGY+ LEC +KCTL +FCKTVCEDVF+VAKAEFRA+WCVA+ QVP+NSGLLFG
Sbjct: 421 LLSQIHEEGYNHLECHRKCTLLVFCKTVCEDVFQVAKAEFRAFWCVASSQVPENSGLLFG 480

Query: 478 GVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPL 537
           G+F+ K+INPMTNAQSCPAGY PL LFE+LKVCVS DYELG +F+VPFGGFFSC +GNPL
Sbjct: 481 GLFSSKSINPMTNAQSCPAGYFPLRLFENLKVCVSQDYELGSRFAVPFGGFFSCTVGNPL 540

Query: 538 VNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP 597
           V+   ++D+ APSLKKCPGGFSQH A+ISDGCQVSYCVK+G+FTGGSL P RLPP+T+PP
Sbjct: 541 VDPAISRDLGAPSLKKCPGGFSQHPALISDGCQVSYCVKSGLFTGGSLPPARLPPFTRPP 600

Query: 598 LMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGI 657
           LMSQ ATNTVIVTNSE ARSWIKD QT+QW+LGEP+ELRRAM VIHGD  G+SGG AAG+
Sbjct: 601 LMSQAATNTVIVTNSENARSWIKDSQTHQWRLGEPIELRRAMNVIHGDGGGLSGGAAAGV 660

Query: 658 TLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 713
           T+GVT  L +VITLAIYGTRK+KKK YQ IEE++SLV   A        E+  SPA
Sbjct: 661 TVGVTTILAVVITLAIYGTRKFKKKAYQAIEERQSLVPGTAATGDTTYQEQGQSPA 716


>UniRef50_UPI0000EBD8A9 PREDICTED: similar to macrophage expressed gene 1 n=1 Tax=Bos
           taurus RepID=UPI0000EBD8A9
          Length = 753

 Score =  959 bits (2480), Expect = 0.0,   Method: Composition-based stats.
 Identities = 265/715 (37%), Positives = 394/715 (55%), Gaps = 30/715 (4%)

Query: 24  GETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDE 83
            + G  GFQ CK  L + VL  LPG GWDNLRN+++G V+   Y+ C TTEDG+Y+IPD 
Sbjct: 34  ADGGPWGFQGCKQQLNVSVLGALPGAGWDNLRNLELGLVLGRAYSQCLTTEDGEYLIPDG 93

Query: 84  VYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKD 143
           +  +P++E+ ++  +++++SW+NY    + S+N E +  S +NGKFS E Q ++   ++ 
Sbjct: 94  MLAVPRRETVVQTRADLMDSWVNYTDAWAASVNAEFSFLSFLNGKFSAECQNVRRYSLQY 153

Query: 144 QAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGT 203
           Q +TTRVQ R+ IY+V+   T +    F + L+ + D LE NQT+ A YLAE+L+  YGT
Sbjct: 154 QTITTRVQRRHSIYSVRVRGTPDFHPDFRQRLLTLSDHLENNQTREAEYLAEMLVFAYGT 213

Query: 204 HVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLT 263
           HV+T V+ GA LVQED V    + +    +  VT +A + F   V       +  ++ L 
Sbjct: 214 HVLTEVEVGATLVQEDQVSRELVGNEDKDRLNVTFAASVLFDRKVGVGDAVSWDKESQLV 273

Query: 264 KDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLP 323
           + Y      S++ S GG PFY G+TL+ WQ+G+ N LVAI R+GLPL   ++P+ LP LP
Sbjct: 274 QAYQRGTVASKIHSRGGPPFYEGLTLQKWQEGVANRLVAIGRSGLPLPALLQPEALPELP 333

Query: 324 GPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSC-DAKVTNFTFGGVY 382
            P V+++   V  A+  YY  N HPGC    +PNF+  AN+DD SC D +  NF+FGGV+
Sbjct: 334 APAVRRVEAAVSRAIGRYYEVNMHPGCVKRGAPNFDPLANVDDGSCTDGQHANFSFGGVF 393

Query: 383 QECTELS---GDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT-- 437
           QEC  ++   G  LC+     N LTG  SCP  Y+   L S+         +C  +C   
Sbjct: 394 QECEAITGPEGGRLCKPYTILNPLTGQTSCPANYTASLLSSEVKVWSERSYQCWPQCQSC 453

Query: 438 --LKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVP-DNSGLLFGGVFTDKTINPMTNAQSC 494
             +   C  +C ++         A WC  +G  P    GLLFGG+++    NP T AQ+C
Sbjct: 454 WLIFTCCHRMCGNLEIQRVVRVNASWCAPSGATPTAAPGLLFGGLYSPGRPNPRTGAQAC 513

Query: 495 PAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLV------NSDTAKDVRA 548
           P+ + PL L   LKVCVS D+ELG   +VPFGGFFSC +GNPL        S+  K+V  
Sbjct: 514 PSSFFPLTLLGDLKVCVSSDWELGVAHAVPFGGFFSCQVGNPLAAQARGQGSEFLKEVFN 573

Query: 549 PS-----LKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP--LMSQ 601
            S        CP G+SQH A +S GCQ+ YC++AG       L +RLPP+   P  L + 
Sbjct: 574 LSVTMDHPMTCPAGYSQHPAYLSSGCQILYCLRAGFLLNPQQLMIRLPPFAARPSLLGNS 633

Query: 602 VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV 661
                 ++ ++   R+W+K   +++W+  +  +   A  +     +  S G   G  LG 
Sbjct: 634 SGLGVSVLVDASGQRAWVKLQGSSRWRQADIHDPSVAAQLRDQGGSQPSAGAVVGACLGA 693

Query: 662 TIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLN---GEEDPSPA 713
            + +  +     +G R+Y+K+ Y+ + E     G LA + TV       E P+P+
Sbjct: 694 VLGVVALALGVTWGFRRYQKRGYRRLPE-----GILAEEQTVYGTAETAESPAPS 743


>UniRef50_Q7SXE0 Macrophage expressed 1 n=10 Tax=Clupeocephala RepID=Q7SXE0_DANRE
          Length = 718

 Score =  933 bits (2412), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/697 (46%), Positives = 452/697 (64%), Gaps = 29/697 (4%)

Query: 30  GFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQ 89
           G ++C+    L  LEVLPGGGWDNLRN+DMGRVM+L+Y+ C+TTEDG Y+IPDEV+ IPQ
Sbjct: 29  GLRLCRKNSSLTALEVLPGGGWDNLRNIDMGRVMNLSYSQCQTTEDGVYLIPDEVFVIPQ 88

Query: 90  KESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTR 149
           K S +E NSE++ SW+  +S+TS S+N +++ FS +N KFSTE QRMKT QVK+ +VT R
Sbjct: 89  KVSGVETNSEIIMSWLEQKSSTSSSVNADVSFFSVLNAKFSTENQRMKTHQVKEGSVTAR 148

Query: 150 VQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSV 209
           VQVRN +YTVK  P   L   F K   +I D +E NQT+ A YL+E L+L+YGTHVITSV
Sbjct: 149 VQVRNHLYTVKAYPDFTLDSRFAKQAEEIADAIENNQTRHANYLSEKLVLDYGTHVITSV 208

Query: 210 DAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSN 269
           DAGA LVQED+++ S++ ++Q+ +++V+ASAG  F + V F +  +    +S +  Y  N
Sbjct: 209 DAGATLVQEDYLKMSYISNSQSDKSSVSASAGANFFDKVKFDIGGNTSQGSSQSSSYQGN 268

Query: 270 RTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKK 329
            T S +QS GG  FYPGITL+ WQ+   N+L AIDR+GLPLH+F+ P   P LP P V K
Sbjct: 269 ITYSLIQSHGGALFYPGITLQKWQQSTLNNLAAIDRSGLPLHYFLNPSTFPDLPTPTVNK 328

Query: 330 LSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELS 389
           L+ TV  A   YY  NT PGC NVDSPNFNFQAN+DD SC+  +TN +FGG+YQ+CT L+
Sbjct: 329 LASTVRKAAERYYKVNTIPGCVNVDSPNFNFQANVDDASCEGPITNLSFGGIYQKCTPLT 388

Query: 390 --GDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT------LKIF 441
             G+++C    QKN  TG +SCP  Y+   L S+  E+G++  EC   C       L   
Sbjct: 389 PDGNIICDETAQKNPATGGYSCPQHYNTTLLHSEVVEKGFNHYECHTHCHSCGFLGLSTC 448

Query: 442 CKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPL 501
           C   C D + V +A+    WC +  + P+NSG LFGG+F     NP+T + SCP  Y   
Sbjct: 449 CDKTCGDSYHVRRAKLETLWCSSTHKTPENSGYLFGGLFGPGIQNPLTKSSSCPPSYFTQ 508

Query: 502 NLFES-LKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQ 560
               + + +C+S DYE+G +FSVPF GFFSC  GNPL N  +          +CP  FSQ
Sbjct: 509 RFLSNGMMICMSNDYEIGTRFSVPFAGFFSCQSGNPLSNGQS----------RCPPQFSQ 558

Query: 561 HLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIK 620
           HLA ISDGCQV YCV++G+F+GG L PVRLPP+T+PP++  +ATNTV V  +E  RSW++
Sbjct: 559 HLAAISDGCQVLYCVQSGVFSGGHLKPVRLPPFTRPPVVGMIATNTVAVM-TEGERSWVR 617

Query: 621 DPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYK 680
             +T  W+L +P ++++  +++  D++ MSGG+ AG+ +G+ + + +V+   +   ++  
Sbjct: 618 VGETKMWRLAKPGDIKQMQSIL--DASEMSGGKKAGVAIGIIVLVALVVAGTVVIMKRRN 675

Query: 681 K-------KEYQEIEEQESLVGSLATDATVLNGEEDP 710
           +       + Y+EI E+ +               E+P
Sbjct: 676 RFSSLKLNRGYEEISEERNESSVEIEQEQNEAANENP 712


>UniRef50_UPI0001796D85 PREDICTED: similar to Macrophage-expressed gene 1 protein precursor
           (Macrophage gene 1 protein) (Mpg-1) n=1 Tax=Equus
           caballus RepID=UPI0001796D85
          Length = 687

 Score =  849 bits (2192), Expect = 0.0,   Method: Composition-based stats.
 Identities = 265/707 (37%), Positives = 383/707 (54%), Gaps = 61/707 (8%)

Query: 23  LGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPD 82
           +G+ G  GFQ CK  L +PVL  LPGGGWDNLRNV++  V+   Y+ C TTE G+Y+I D
Sbjct: 19  MGDPGAPGFQGCKQTLNVPVLGALPGGGWDNLRNVELELVLRRYYSQCLTTEAGEYLIQD 78

Query: 83  EVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVK 142
           +++ +PQ+ES +E   E++                     + +NGK S + Q +K   ++
Sbjct: 79  QLHVVPQRESFVETRGELI---------------------NDLNGKSSIDCQNVKKYNLE 117

Query: 143 DQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYG 202
            Q VT RVQVR+ IY+VK     +    F + L+ + D LE +Q + A YLAE+L+L YG
Sbjct: 118 YQMVTARVQVRHSIYSVKAPEIPDFQPTFRQHLLALSDHLENDQIREAEYLAEMLVLWYG 177

Query: 203 THVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSL 262
           THV+T V+AGA LVQED VR   +      +N VT++A   F ++VNF     + +Q+ L
Sbjct: 178 THVLTDVEAGATLVQEDQVRRELVDSQAGERNNVTSTASAVFFHMVNFGDAASWQAQSQL 237

Query: 263 TKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL 322
            +DY+ N   S+++S GGVPFYPGITL+ WQ+GI+N LVAI R+ LPL   ++P+ LP L
Sbjct: 238 FQDYVRNTVASKMRSQGGVPFYPGITLQKWQEGISNRLVAIGRSELPLPALLQPEALPEL 297

Query: 323 PGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVY 382
           P P V++++  V  A+  YY  N  PGC    +P FN QAN++D SC    +NF+FGGV+
Sbjct: 298 PAPTVQRVAAAVRRAIHRYYAVNALPGCLRRGAPAFNPQANLEDGSCGGGRSNFSFGGVF 357

Query: 383 QECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT----L 438
           QEC  +SG                   P  Y+   L S+       R EC+++C      
Sbjct: 358 QECEAVSGQT-----------------PTSYTASALHSELKTWSEPRPECQQQCRKCWLF 400

Query: 439 KIFCKTVCEDVFRVAKAEFRAYWCVA-AGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAG 497
              C+TVC    + +     A WCV     +P  SG LFGG+++    NP T AQ+CP+ 
Sbjct: 401 FQCCQTVCATHEQRSVVRLAASWCVPSQASLPATSGFLFGGLYSPGNSNPFTKAQACPSY 460

Query: 498 YIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLV-----------NSDTAKDV 546
           +  L LF  LKVCVS D ELG   +VPFGGFFSC +GNPLV                +D 
Sbjct: 461 FYALTLFGDLKVCVSSDLELGAAQAVPFGGFFSCQVGNPLVGLLKGQSPGLLQEMFCQDS 520

Query: 547 RAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLM--SQVAT 604
                 KCP G+SQH A +S+GCQ+  C++AG   G     VR+PP+   P +  S  A 
Sbjct: 521 PTDHPMKCPAGYSQHQAYLSNGCQIFCCLRAGALLGQQQAAVRMPPFLPRPPLLNSSSAH 580

Query: 605 NTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIA 664
           +  ++ +S   R W++   ++ W+     +L  A  ++    +  S G  AG  +G  +A
Sbjct: 581 SLSVLVDSTGQRVWVRLQGSDCWQQANINDLSLAAKLLSQAGSKPSIGAIAGSWVGTLVA 640

Query: 665 LGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPS 711
           + +V     YG R+YKK  Y+ ++      G L  +       E  +
Sbjct: 641 VVVVTLGISYGFRRYKKGGYKRLQ-----GGILTEEQGGYGTTETTA 682


>UniRef50_Q6RYF9 Macrophage expressed protein n=5 Tax=Eumetazoa RepID=Q6RYF9_HALCO
          Length = 730

 Score =  820 bits (2118), Expect = 0.0,   Method: Composition-based stats.
 Identities = 261/712 (36%), Positives = 381/712 (53%), Gaps = 38/712 (5%)

Query: 5   MALVLIWMIIACAEADKPLGETGTTGF-----QIC-KNALKLPVLEVLPGGGWDNLRNVD 58
           +  VL+  I+A     + L       F     + C  +  KL   EVLPG GWDNLRNVD
Sbjct: 2   LGFVLVVSIVASVSGGELLDSVKKPEFPKGDVRACYGDNKKLERFEVLPGQGWDNLRNVD 61

Query: 59  MGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTE 118
            G V+   Y+ C+TTEDG+Y+IPD V TIP K S L + +E++  W +Y STT+  +N +
Sbjct: 62  AGLVVVYNYSRCRTTEDGRYLIPDTVNTIPLKASKLNVYAELISHWSSYTSTTAHGVNVD 121

Query: 119 LAL---FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKAL 175
             L     +V+GKFS+ ++ +K+ Q+ D++ TTRVQ+R   Y+ K  P + L   F   L
Sbjct: 122 AGLKYDSVQVSGKFSSGYESVKSKQIGDKSYTTRVQLRYVRYSAKLQPDASLHPTFKTRL 181

Query: 176 MDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT 235
           + I   L+ N+T  A Y +ELL+ ++GTHV+TSVDAGAALVQED V S F+   + ++N 
Sbjct: 182 LSIAGSLQLNKTDQARYDSELLVRDFGTHVVTSVDAGAALVQEDQVSSEFVNSRKFTKNQ 241

Query: 236 VTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFY-PGITLETWQK 294
           +TA A  +   I +  V     +   + K Y  +R++S++ + GG  F     T   W  
Sbjct: 242 ITAGASASLFGIFSIDVSYHSSTSNEVKKAYEQSRSSSQIDTLGGPMFKASNFTANDWTN 301

Query: 295 GITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVD 354
            + + LVA+DR+G PL F I    LP LP  ++ +L   VE  + HYY FNT+ GCT +D
Sbjct: 302 EVDHELVAVDRSGDPLFFLINSASLPELPNSVLYQLQNLVEETILHYYEFNTYRGCTELD 361

Query: 355 SPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGD---VLCQNLEQKNLLTGDFSCPP 411
           SPNF+  AN+DD +C +  TN TFGGVYQ C+  SG     LC  L+Q N  TG  +CP 
Sbjct: 362 SPNFSPAANLDDGTCKSPYTNLTFGGVYQTCSMSSGSNNGDLCSGLDQVNPKTGGHTCPD 421

Query: 412 GYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDN 471
           GY  V L +    +  S   C   C L   C   C D +  ++A +  +WC A G V  +
Sbjct: 422 GYESVELHTGRLSDSKSVHSCH-SCWLFFKC---CHDNYYHSEATYIMHWCAATGPVSQD 477

Query: 472 SGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSC 531
           SG LFGG++T +  NP+T  ++CP  +    L + L +C+S DYELG K+S+PFGGF SC
Sbjct: 478 SGYLFGGLYTSQLNNPLTQGKTCPVNFYTRTLGKDLHICISDDYELGMKYSMPFGGFISC 537

Query: 532 IMGNPLVNSDTAK---DVRAP-------------SLKKCPGGFSQHLAVISDGCQVSYCV 575
             GNPL  +   K   D+ +                K CP G+SQHLA +  GC+++YC+
Sbjct: 538 TTGNPLAMNPKPKSKGDMNSALPSLHSFFQGSKTWPKHCPKGYSQHLAYVDQGCEINYCL 597

Query: 576 KAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLEL 635
            AG  +   L  +R PP+   PL+     N V+        +W K+ +  Q+      E 
Sbjct: 598 LAGSLSEVGLPKIRRPPFQTAPLLLPSTENHVVF--DPVTLTWRKNQEAMQFISARVGEA 655

Query: 636 RRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKKKEYQEI 687
             + T     +   +G  A   TLG  +   +++ L     R+     Y+ +
Sbjct: 656 TPSSTGSGMSAGAAAG-IAVVATLGCVVISTVIVVLIK--RRRKSSAGYRHL 704


>UniRef50_UPI0000F2D8B8 PREDICTED: similar to Macrophage expressed gene 1 n=1
           Tax=Monodelphis domestica RepID=UPI0000F2D8B8
          Length = 1065

 Score =  801 bits (2068), Expect = 0.0,   Method: Composition-based stats.
 Identities = 254/625 (40%), Positives = 364/625 (58%), Gaps = 28/625 (4%)

Query: 64  DLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFS 123
              Y+ C+ TED +Y+IPD+V+ +P++ES LE +SE++  W  Y    SL+IN E +  S
Sbjct: 150 GRNYSLCRVTEDREYLIPDQVHVVPRRESMLETHSEIIRDWRTYTDAFSLTINAEASFLS 209

Query: 124 RVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLE 183
            +NGKFS   QR K   V DQ +TTRVQ R  IY++   P   L+  F + L+ I + LE
Sbjct: 210 ILNGKFSASSQRSKVHSVYDQTITTRVQARQHIYSLAAQPPWVLAEAFRQQLLHISEHLE 269

Query: 184 KNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIA 243
            N+++ A+Y AELL+L YGTHV+T V+AGA+L+QED V+ + L +N   +  + ASA   
Sbjct: 270 NNRSQQASYQAELLVLAYGTHVLTEVEAGASLMQEDQVKRALLDENSTKKVGIAASASAI 329

Query: 244 FLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAI 303
           F + +          +     +Y+ N  +S++Q+ GG PFYPGITL+ WQ+ I N LVAI
Sbjct: 330 FFSRIQLGANLTGQVRNQQQWEYVKNTVSSKIQNHGGEPFYPGITLQKWQQSIPNRLVAI 389

Query: 304 DRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQAN 363
            R+GLPL FFI P+ LP L  P V++L+ TV+ A++ YY  NT+PGC    + NFNFQAN
Sbjct: 390 GRSGLPLPFFITPEALPELQVPSVRRLALTVQKAIQQYYAVNTYPGCLQPKASNFNFQAN 449

Query: 364 MDDDSCDAKVTNFTFGGVYQECTELSG---DVLCQNLEQKNLLTGDFSCPPGYSPVHLLS 420
           +DD SC+    +FTFGGV+Q+C  +SG   + LCQ     N LTG  SCP  YS + L S
Sbjct: 450 VDDGSCEKAKHHFTFGGVFQKCQAVSGKGAETLCQPYRTANPLTGAASCPKNYSALLLNS 509

Query: 421 QTHEEGYSRLECKKKC----TLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVP-DNSGLL 475
           +       ++EC+K+C     L   CKTVC +    +     AYWC  AG       G L
Sbjct: 510 ELRSSNVPQMECRKQCSSCYWLFQCCKTVCGNREHPSVVSLSAYWCSPAGSPALSKPGFL 569

Query: 476 FGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGN 535
           FGG++T+   NP+T AQ+CP  + PL LFE LKVCVS ++E+G   ++PFGGFFSC +GN
Sbjct: 570 FGGLYTNTQRNPLTKAQTCPHFFYPLVLFEDLKVCVSGNHEMGKSSAIPFGGFFSCRVGN 629

Query: 536 PLVN-----------SDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGS 584
           PL                 +D       KCP G+SQH A +S+GCQ+ YC++AG      
Sbjct: 630 PLAGFLQGQSPGMLKEVFYRDSPTVYPMKCPPGYSQHQAYLSEGCQILYCLQAGALFAQQ 689

Query: 585 LLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHG 644
           L+P+ LPP+ +PPL+++  T+   + +S+  +    D  T +   G   +          
Sbjct: 690 LVPIHLPPFIRPPLLNESYTDVDALVDSDANQISNLDDATKEALKGSGGD---------Q 740

Query: 645 DSNGMSGGEAAGITLGVTIALGIVI 669
           + +G      AG+ L + I+L IV 
Sbjct: 741 EHSGSGTWVTAGVWLPLVISLVIVA 765


>UniRef50_B3F732 Macrophage expressed protein 1-like protein n=1 Tax=Crassostrea
           gigas RepID=B3F732_CRAGI
          Length = 621

 Score =  798 bits (2062), Expect = 0.0,   Method: Composition-based stats.
 Identities = 240/623 (38%), Positives = 342/623 (54%), Gaps = 37/623 (5%)

Query: 39  KLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNS 98
            +   EVLPG GWDNL+N D G ++   Y+ C+TT+DGQY+IPD VYT+P K S LE+  
Sbjct: 4   NVARFEVLPGLGWDNLQNKDAGMLVQYNYSECRTTDDGQYLIPDGVYTVPLKSSKLEVFG 63

Query: 99  EVLESWMNYQSTTSLSINTELALF---SRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNR 155
           E+ + W N+ STTS S+N E  L      ++GK+S E   ++  Q+ D++VTTRVQ R  
Sbjct: 64  ELFQHWNNFTSTTSSSVNVEAGLHLGSFGISGKYSHESDSVRKHQIMDRSVTTRVQARYA 123

Query: 156 IYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAAL 215
            Y+    P + L+  F   L +I   ++ N+T MA Y ++LL+ +YGTHVI+SV    + 
Sbjct: 124 RYSALLQPDTPLNPAFRDRLRNIAYYIQTNKTNMARYQSQLLVRDYGTHVISSVQRVPSS 183

Query: 216 VQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRV 275
           +    +R   +      +  V           V    E  + + T +   YL NRT+S +
Sbjct: 184 LSLTRLRRRSVTVTAWDRRQVVGRGQCLVYERVYVGAEYKHSTSTEVIDQYLGNRTHSVI 243

Query: 276 QSFGGVPFYP-GITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTV 334
            + GG  F P   TL  W  G++  LVA+D++G P++  I    LP LP  ++  L +TV
Sbjct: 244 NAIGGPVFQPNNFTLNQWASGLSGDLVAVDKSGYPIYELISAQTLPELPPSILFPLVQTV 303

Query: 335 ETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELS--GDV 392
           ++AV  YY FN + GCTN+DSPNF+F AN+DD +C++  TN+TFGGVYQ+C +       
Sbjct: 304 KSAVEEYYKFNIYRGCTNLDSPNFSFIANVDDGTCESPETNYTFGGVYQQCKQSGQLSQN 363

Query: 393 LCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRV 452
           LC  L QKN LTG  SCP GY  V L   T     SR  C     L +  +  C++    
Sbjct: 364 LCNGLVQKNPLTGAQSCPSGYESVLLNEGTRSATESRRRCHHCGFLGL--RHCCDNYNVY 421

Query: 453 AKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVS 512
             A+++++WCVA G V   SG  FGG++T+K  NP+T ++ CP  + PL L   ++VCVS
Sbjct: 422 GSAKYQSFWCVAQGHVDQQSGFQFGGIYTNKIDNPLTQSRGCPLYFYPLKLGLGMQVCVS 481

Query: 513 LDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAP---------------SLKKCPGG 557
            DYELGF++SVPF G FSC+ GNPL         + P                 + CP G
Sbjct: 482 DDYELGFRYSVPFAGLFSCMTGNPLAVHQD-TSFKNPDMLHSLSSYLKASNNWPRGCPTG 540

Query: 558 FSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP----LMSQVATNTVIVTNSE 613
           +S HLA I + C+++YCVKA  F+   L PVR PP+   P    + S ++   +I T  E
Sbjct: 541 YSMHLATIENSCEINYCVKANAFSDKGLPPVRRPPFMDLPGDAYVDSGISEEYMISTGGE 600

Query: 614 TARSWIKDPQTNQWKLGEPLELR 636
           T   W          LG P + R
Sbjct: 601 T---WTDL------TLGGPAQFR 614


>UniRef50_A7SEK6 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
           RepID=A7SEK6_NEMVE
          Length = 583

 Score =  794 bits (2051), Expect = 0.0,   Method: Composition-based stats.
 Identities = 242/595 (40%), Positives = 337/595 (56%), Gaps = 23/595 (3%)

Query: 44  EVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLES 103
           EVLPGGGWDNLRN+ MG V  + Y+ C++++DG++++PD V+  P K+S +   +E  + 
Sbjct: 1   EVLPGGGWDNLRNLHMGAVSAMNYSLCRSSDDGKFLVPDNVFLYPVKKSKVNTFAEFYDH 60

Query: 104 WMNYQSTTSLSINTEL---ALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVK 160
           W NY STT+ SIN E      F  V+G FS+E++ +K  QV+D+ VTTRVQ+R+  YT K
Sbjct: 61  WNNYSSTTTKSINAEAKASFGFGSVSGSFSSEYESVKKHQVEDKTVTTRVQLRHVFYTAK 120

Query: 161 TTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDH 220
             P S L   F   L++I   L+ N T  A++LA++L+ ++GTH ++SVDAGA L + DH
Sbjct: 121 LQPDSPLQPAFKDRLLEIASHLQHNNTAYASFLAQVLVRDFGTHYVSSVDAGAVLAKVDH 180

Query: 221 VRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG 280
           +   F+ D+   ++ +TASA  +F +           + T    +Y      S   ++GG
Sbjct: 181 LTKKFVADSNEDKSKITASASASFFHFFGASGSYSKSTDTKTLDEYTKATVYSTTYTYGG 240

Query: 281 VPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRH 340
            PF    T+  W+  + + LVA+DR+G PLH+ I P  LP L      +L+  V+ A++ 
Sbjct: 241 PPFRVNFTINEWEDKMLDELVAVDRSGDPLHYTITPGSLPELCEQATFQLAAVVKNAIKQ 300

Query: 341 YYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELS--GDVLCQNLE 398
           YY  NT  GCT +DSPNF+FQANMDD SC +   N+TFGGVYQ C          C  L 
Sbjct: 301 YYIHNTIKGCTKMDSPNFSFQANMDDGSCQSPTNNYTFGGVYQTCQTDGSPSSDPCAPLA 360

Query: 399 QKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFR 458
           QKN LT D++C PGY PV +      +G +   C K C         C    +     F 
Sbjct: 361 QKNPLTADYTCTPGYEPVLVH-----QGRTPQSCHKDCHRVWLFFKRCS--VQCGFGSFS 413

Query: 459 AYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELG 518
            YWCVA   VP NSG LFGG+++D   NP+T   SCP  +  L    ++KVCVS DYELG
Sbjct: 414 TYWCVAKSAVPANSGYLFGGLYSDVLKNPLTQDHSCPLKFYALKFGATMKVCVSDDYELG 473

Query: 519 FKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSL--KKCPGGFSQHLAVISDGCQVSYCVK 576
           ++ S+PFGGFFSC  GNPL         + P    K CP GFSQHL  I   C++ YCVK
Sbjct: 474 YQQSLPFGGFFSCNAGNPLA-------FKKPPTGDKGCPTGFSQHLGAIEANCEIQYCVK 526

Query: 577 AGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQ-TNQWKLG 630
           + +F    L  VR PPY  PP +   +   +++ N +T + W K      QW L 
Sbjct: 527 SNVFNLQGLPIVRRPPYLSPPAVYNYSVP-MLLVNEDTGQIWFKRAGNMPQWLLA 580


>UniRef50_Q4W1E5 Macrophage expressed protein n=1 Tax=Suberites domuncula
           RepID=Q4W1E5_SUBDO
          Length = 676

 Score =  692 bits (1786), Expect = 0.0,   Method: Composition-based stats.
 Identities = 212/603 (35%), Positives = 324/603 (53%), Gaps = 74/603 (12%)

Query: 22  PLGETGTTGFQIC-KNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYII 80
           P G+      + C     KL +L+V+PG GWDNLRN + G +   +Y+ CK T D +Y+I
Sbjct: 57  PRGDP-----RNCLSGNPKLNILQVVPGIGWDNLRNSETGILTSFSYSQCKVTYDRRYLI 111

Query: 81  PDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQ 140
           PDE + IP K S ++  +E+ + W  Y+S TS SIN     F ++ G             
Sbjct: 112 PDETFAIPIKTSTIDYQAELFDHWDAYKSVTSRSINAGFDFFGKIGG------------- 158

Query: 141 VKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILN 200
                                               +I   L+ N T+ A Y A++LI +
Sbjct: 159 ------------------------------------EILSLLKSNDTESADYAAQILIRD 182

Query: 201 YGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQT 260
           YGTH ITS+DAGA L++ED+++S+ + + +   ++++ +AG+ F +++  +    + S +
Sbjct: 183 YGTHCITSIDAGAVLIKEDNLKSTIMSNYKGRADSLSTAAGVEFYDMLKLRASAGFSSYS 242

Query: 261 --SLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFF----- 313
             S  K Y  NRT+SR+ ++GG P+  G+ L  W+  + N+LVA DR+G P H       
Sbjct: 243 GDSDLKAYRQNRTSSRLYTYGGPPYKLGMNLSRWENDLMNNLVATDRSGKPSHSLSTTQS 302

Query: 314 IKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDS-CDAK 372
           +KP+        L+++L   V++AV  YY +NTH GC N  +PN + Q N      C   
Sbjct: 303 LKPEVTTSQEVFLLRRL---VKSAVSQYYHYNTHTGCKNPKAPNLDHQTNNGAPGVCKEP 359

Query: 373 VTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLEC 432
             N+TFGGV+Q C   +G+ +C  L QKN LTG +SCP  +  + L   T      R  C
Sbjct: 360 SANYTFGGVFQSCRS-NGNDICGKLLQKNPLTGGYSCPKNFKALLLQLGTERSHKMRRVC 418

Query: 433 --KKKCTLKIF-CKTV--CEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINP 487
             K+KCT  +F C  V  C  V  V  A ++ YWC    + P   G +FGG++++   NP
Sbjct: 419 VWKRKCTFFVFNCHDVDDCTFVPSVEIASYQTYWCAPNKKNPPKFGYMFGGIYSNDIQNP 478

Query: 488 MTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVR 547
           +T + SCP  ++PL + E   VCVS DYELG +FS+PFGGFFSC+ GN L  + +++ + 
Sbjct: 479 ITRSCSCPTHFLPLRMGERATVCVSEDYELGHQFSLPFGGFFSCVSGNVLAGNGSSEFLN 538

Query: 548 AP--SLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATN 605
            P     +CPGGF+QHLA+   GC+V++CVKAG     S L + LPP+   P + + +T+
Sbjct: 539 NPKDWPMRCPGGFTQHLALTEKGCRVNFCVKAGSLLRASDLELVLPPFDPKPTLRKNSTS 598

Query: 606 TVI 608
            + 
Sbjct: 599 DLF 601


>UniRef50_C4Q3P0 Expressed protein n=2 Tax=Schistosoma RepID=C4Q3P0_SCHMA
          Length = 1103

 Score =  575 bits (1483), Expect = e-162,   Method: Composition-based stats.
 Identities = 196/605 (32%), Positives = 296/605 (48%), Gaps = 70/605 (11%)

Query: 2   NSFMALVL---IWMIIACAEADKPLGETGTTGF-QICKNALKLPVLEVLPGGGWDNLRNV 57
           N+   L++      +I  + ++ P  +T +    + C        L VLPG GWDNL N 
Sbjct: 294 NNHHVLIITNIYSSVIEKSSSENPSDQTISYSLPKECTLFPNQKYLSVLPGFGWDNLVNR 353

Query: 58  DMGRVMDL-TYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSIN 116
           + G ++D+  Y+ C+ + DG+++IPDE+   P K S ++++SEV ES    +S  + SIN
Sbjct: 354 ERGPIIDVEKYSLCRRSVDGKFLIPDEITVQPIKNSEIKLSSEVYESISQCRSLVAYSIN 413

Query: 117 T----ELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRV-----------QVRNRIYTVKT 161
           +    E + F R+NG FS++ + ++   VK   VT               +RN +  V  
Sbjct: 414 SAVGGEYSYF-RINGDFSSDKETLREKLVKHGNVTMETIELFNNGLIGNTLRNSLGIVTN 472

Query: 162 TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHV 221
                LS G                   A YLA+L++ ++GTH I SV AG  L + D +
Sbjct: 473 DNFKSLSQGMN-----------------AFYLADLVVRDFGTHCINSVYAGGVLAKIDTL 515

Query: 222 RSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGV 281
            ++ L   +  +  + ASA I+F N+ N K+        SL ++Y S  T S++ ++GG 
Sbjct: 516 DTNSLNTKKEDRWHLGASATISFANLFNVKLGGSANVNDSLIQNYESKITYSQILTYGGP 575

Query: 282 P-FYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRH 340
             +   + L  W+ G+ N LVAIDR+G P++  I    LP L   ++ +L  T+++AV  
Sbjct: 576 IIYMSNVNLSLWESGLDNQLVAIDRSGQPIYELITDRSLPELSSHMIVRLVATIKSAVER 635

Query: 341 YYTFNTHPGCTNVDSPNFNFQANMDDDSCD---AKVTNFT--FGGVYQECTELSGDVLCQ 395
           YY  NT  GC N  S  ++ +AN+    CD    ++TN T   GGVYQ+CT    D LC 
Sbjct: 636 YYKANTVVGCMNPLSVFYDNEANVASPECDLQSKQITNTTLYLGGVYQKCT--GPDDLCL 693

Query: 396 NLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLK-IFCKTVCEDVFRVAK 454
                N LTGD  C  GY  + LL Q   + YS   C +K   K   C T C        
Sbjct: 694 GETIPNPLTGDLFCSQGYVSIQLLPQQVRKCYSV--CDEKSWFKNPECTTQC-------- 743

Query: 455 AEFRAYWC---------VAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFE 505
           A   +YWC          +      +SG LFGG++TDK +N +T   +CP  Y P+ L  
Sbjct: 744 AITESYWCSRDPSLSSSSSNILDNSDSGYLFGGLYTDKEVNSLTKQYNCPQYYWPITLGR 803

Query: 506 SLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVN----SDTAKDVRAPSLKKCPGGFSQH 561
            +++C+S D ELG K+S+PFGGF+SC  GNPL      + T K        + P  F   
Sbjct: 804 RMRICLSTDRELGGKYSLPFGGFYSCYSGNPLTALININQTDKIDSNEQHTRIPEWFKIQ 863

Query: 562 LAVIS 566
              +S
Sbjct: 864 QERMS 868



 Score =  101 bits (251), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 22/132 (16%)

Query: 538  VNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP 597
            V +D ++   A   KKCP G++ HLA + D CQV+YCV+A          ++ PP+  P 
Sbjct: 919  VQNDFSQLFAALWPKKCPVGYTAHLAAMEDICQVNYCVQANFLKEQVRRQLKRPPFVLP- 977

Query: 598  LMSQVATNTVIVTNSETARSWIKDPQ-----------TNQWKLGEPLELRRAMTVIHGDS 646
                      I TN E   S+  DP            ++ +KL +      + +    D 
Sbjct: 978  ----------IYTNEEKLPSFSNDPHGRSILTELSFDSHLFKLSDSNNFIESSSNELHDK 1027

Query: 647  NGMSGGEAAGIT 658
            NG    +  G  
Sbjct: 1028 NGNIIRKINGRW 1039


>UniRef50_Q2XSC0 Macrophage expressed protein (Fragment) n=1 Tax=Mytilus edulis
           RepID=Q2XSC0_MYTED
          Length = 338

 Score =  456 bits (1172), Expect = e-126,   Method: Composition-based stats.
 Identities = 127/344 (36%), Positives = 191/344 (55%), Gaps = 15/344 (4%)

Query: 210 DAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSN 269
           D+GA++V+ DHV+   L D+   +  ++A+AG        F V+        +   YL++
Sbjct: 3   DSGASIVKVDHVKRELLQDDTIDKFQISAAAGAEL-----FGVQVGITIPAEVMTKYLAS 57

Query: 270 RTNSRVQSFGGVPFYP-GITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK 328
           +T+S + + GG  + P   T+  W K I  +LV++DR+G PLHF I     P L   +V 
Sbjct: 58  KTHSSILTHGGPLYLPVNFTINDWVKQIDQNLVSVDRSGDPLHFIINEYMFPELSISIVT 117

Query: 329 KLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKV--TNFTFGGVYQECT 386
             +  VE+A++ YY  NTH GCTN DSPN+N+ AN+DD +C+  +  TN  FGGV+Q C 
Sbjct: 118 DTAAAVESAIKTYYKMNTHRGCTNRDSPNYNYLANVDDGTCEYNLNATNTNFGGVFQTC- 176

Query: 387 ELSGDV--LCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKT 444
            ++G++  +C     KN LTGDFSCP G+  V L         ++ E  + C+  +   +
Sbjct: 177 NVTGNIDGICDTFLSKNPLTGDFSCPNGFIAVPLFLG----HDNKEEVHRTCSKYMIFWS 232

Query: 445 VCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLF 504
            CE    +  A +++YWC   G      G LFGG++T +  N +T  QSCP  +  + + 
Sbjct: 233 HCETTSNLGTASYQSYWCCPQGGNQSFPGYLFGGLYTTQLPNVVTQHQSCPQYFTAIGIA 292

Query: 505 ESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRA 548
           E LK+CVS D E GF++S+PFGGFFSC   N L  +  A    A
Sbjct: 293 EDLKICVSDDIENGFQYSIPFGGFFSCQNDNLLAANQNATHCHA 336


>UniRef50_Q80VB7 Mpeg1 protein (Fragment) n=1 Tax=Mus musculus RepID=Q80VB7_MOUSE
          Length = 232

 Score =  383 bits (983), Expect = e-104,   Method: Composition-based stats.
 Identities = 231/232 (99%), Positives = 232/232 (100%)

Query: 482 DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD 541
           DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD
Sbjct: 1   DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD 60

Query: 542 TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ 601
           TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ
Sbjct: 61  TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ 120

Query: 602 VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV 661
           VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV
Sbjct: 121 VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV 180

Query: 662 TIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 713
           TIALG+VITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA
Sbjct: 181 TIALGVVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 232


>UniRef50_Q5BVJ5 SJCHGC08097 protein (Fragment) n=1 Tax=Schistosoma japonicum
           RepID=Q5BVJ5_SCHJA
          Length = 205

 Score =  144 bits (363), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 44/117 (37%), Positives = 61/117 (52%), Gaps = 17/117 (14%)

Query: 432 CKKKCTLKIF-CKTVCEDVFRVAKAEFRAYWCVAAGQVPDNS--------GLLFGGVFTD 482
           C +K   K   C T C        A   +YWC     +  +         G LFGG++TD
Sbjct: 8   CNEKSWFKSRDCTTNC--------AITESYWCSRDPSLSSSPKVLDIDENGYLFGGLYTD 59

Query: 483 KTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVN 539
           K +N +T   +CP  Y P+ L   +++C+S D ELG K+S+PFGGF+SC  GNPL  
Sbjct: 60  KEVNSLTKQYNCPQYYWPIALGRRMRICLSSDRELGGKYSLPFGGFYSCFSGNPLTG 116


>UniRef50_Q23QV7 E1-E2 ATPase family protein n=4 Tax=Tetrahymena thermophila
           RepID=Q23QV7_TETTH
          Length = 1982

 Score = 70.1 bits (170), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 56/302 (18%), Positives = 103/302 (34%), Gaps = 25/302 (8%)

Query: 72  TTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFST 131
            + D  Y IPD V    +K   +  +S+ + +  +YQ++ S  +N + +LF+  +   S 
Sbjct: 87  VSPDRAYFIPDGVRLTIEKSCLITFSSKDVSTLNDYQNSLSAQVNGKGSLFAA-SFSASA 145

Query: 132 EFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQL--EKNQTKM 189
           +FQ+M+    +              + +            +  L+D   QL    N T  
Sbjct: 146 DFQQMQDTLSQKDNQCIHSFATCSAFDLSFYNDPNSIPLLSLQLVDKIQQLYSYSNYTNE 205

Query: 190 ATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVN 249
             Y  +      GTHV TS+  G+          S     Q S     AS G +      
Sbjct: 206 REYYYDFFDSW-GTHVATSIKLGSLFGY--QFIMSSSSVQQQSNLGFDASVGASLY---G 259

Query: 250 FKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLP 309
            + +            + S+  +    S G  P    +    W     +  + I     P
Sbjct: 260 VQGKVSTDYSQQQLNSFQSSLKSWSSYSMGATP-NANLDASEWATQTLDTPMPIKTDLTP 318

Query: 310 LHFFIKP-DKLPGLP--GPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDD 366
           ++ FI      P +P     +  +   ++  +  Y        C +       FQ+N+D+
Sbjct: 319 IYEFISQYQNNPAIPIDSATLTYVVNAMQNYIIQY--------CYDR----LQFQSNLDN 366

Query: 367 DS 368
            S
Sbjct: 367 CS 368


>UniRef50_D2WL87 MAC/perforin-and kringle-domains-containing protein (Fragment) n=1
           Tax=Pomatoceros lamarckii RepID=D2WL87_9ANNE
          Length = 579

 Score = 70.1 bits (170), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 44/272 (16%), Positives = 83/272 (30%), Gaps = 18/272 (6%)

Query: 73  TEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQST--TSLSINTE-LALFSRVNGKF 129
           T D +Y IP     I          SE + S   ++ +  TS S+N          N  +
Sbjct: 123 TYDCKYFIPSGFEVISVPACQTSFTSEEMRSEQEFKQSLATSASVNGGGWGASFSANVDY 182

Query: 130 STEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKM 189
            +  + M++            Q      T+       L+  F KA+ D+         + 
Sbjct: 183 QSSMESMQSTNSIYMISQASCQSYQS--TLHILNPPPLNEFFVKAVEDLSQSEGSADEEE 240

Query: 190 ATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVN 249
             Y       ++GTH  T +D GA  + +  +        +   ++++ SA  ++  IV+
Sbjct: 241 KYYE---FFKDFGTHYPTKMDFGARYINKHKINRQ--AYRKLQDSSLSVSAQASYEGIVS 295

Query: 250 FKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLP 309
                   +      D       +   + G     P   + +W   I +  V I      
Sbjct: 296 VSGSASATTSQKSAVDNFKEMVETETITMGS---LPSGDMGSWAASIKSTAVPIKYKLES 352

Query: 310 LHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
           +                   L+  V   +  Y
Sbjct: 353 IENLFTATFFKSRSA-----LAAAVRAKIIEY 379


>UniRef50_A0T3F5 Apextrin n=1 Tax=Acropora millepora RepID=A0T3F5_ACRMI
          Length = 854

 Score = 70.1 bits (170), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 43/260 (16%), Positives = 97/260 (37%), Gaps = 15/260 (5%)

Query: 66  TYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFS-- 123
            Y +  TT DG++ +PD ++ +      +E NSE   S  +Y ++ +  + T+   F   
Sbjct: 264 NYDSGMTTSDGKWAVPDGLFFLITVSCVIEFNSEESRSSSSYMNSLTNEVGTDSKFFGAY 323

Query: 124 -RVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQL 182
            + N K S++ + +   +     V ++        ++      +L    T  ++    + 
Sbjct: 324 FKANVKVSSKNEEL--HEASYSYVKSQAVCSYYKGSI----FPDLPPRLTPQILATMKKC 377

Query: 183 EKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGI 242
             N T         L+  +GTH I     G+    E  + +    + Q++   V  +AG 
Sbjct: 378 SDNPTDDNF---NNLVEYFGTHYIAQGVMGSKFGSESKLSTEKYEELQSNGINVGTAAG- 433

Query: 243 AFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVA 302
            +  + +   + +  SQ    + + + R +    ++G      G +  TW    +   + 
Sbjct: 434 -YEGMFSAGYQQETDSQREQREAFENARESKFSYTYGTQMPADG-SANTWASQTSQTPMP 491

Query: 303 IDRAGLPLHFFIKPDKLPGL 322
           I+     +   +       L
Sbjct: 492 INIELTSISELLTDTFKTDL 511


>UniRef50_Q23QV5 MAC/Perforin domain containing protein n=1 Tax=Tetrahymena
           thermophila SB210 RepID=Q23QV5_TETTH
          Length = 518

 Score = 68.2 bits (165), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 62/323 (19%), Positives = 117/323 (36%), Gaps = 26/323 (8%)

Query: 62  VMDLTYTNCKTTE---DGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTE 118
           +++L Y N   T    D  Y +PD V    +K   +   S+ + S   Y+ + S S+  +
Sbjct: 77  ILELDYNNNLWTNINPDRSYYVPDNVSLTVEKSCIVSFQSQEVNSLSQYRDSLSSSVQFQ 136

Query: 119 LALFSRVNGKFS--TEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALM 176
              F+   GKFS  +++Q ++             Q R  I+ +    +   +   T  L 
Sbjct: 137 AKYFA---GKFSASSDYQEVQDGLNSANIQYIESQARCSIFQLDVYNSPSQNAQLTPQLQ 193

Query: 177 DICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTV 236
                L  NQT    Y     I  +GTHV+TSV+ G+    +  +       NQ +Q  V
Sbjct: 194 QALFTLAFNQTSQNDYYD--FIDTWGTHVVTSVNLGSRFGYKYQMDK--YQSNQLTQQGV 249

Query: 237 TASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGI 296
             S   ++ +           +Q    +++    T+    S G  P        +W +  
Sbjct: 250 NLSVSASYFSSSGSASGAYNQTQ---IQNFTQAMTSWSSYSIGATP-DANQDPLSWAQQT 305

Query: 297 TNHLVAIDRAGLPLHFFIKPDKLP--GLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVD 354
            +  + I+ + L    F+        GL    +  +   +   ++ Y        C N  
Sbjct: 306 LDTPMPINISILSFDDFLNKFSFSVNGLTSSQLNTVISNLSQYLQTY--------CANRL 357

Query: 355 SPNFNFQANMDDDSCDAKVTNFT 377
             N    A  D +   +++  ++
Sbjct: 358 LVNGKIDACADQEVSSSQIFQYS 380


>UniRef50_Q1CW76 Putative uncharacterized protein n=1 Tax=Myxococcus xanthus DK 1622
           RepID=Q1CW76_MYXXD
          Length = 1392

 Score = 64.7 bits (156), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 45/199 (22%), Positives = 68/199 (34%), Gaps = 55/199 (27%)

Query: 369 CDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYS 428
           C+    +  FGG +                  N  TG  SCP GY+       TH   +S
Sbjct: 755 CELPAKSLDFGGAF--------GFFNNGTLSPNPATGAASCPEGYTKTQAY-GTHGRDWS 805

Query: 429 RLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPM 488
              C +                            +  G    + G ++G V      NP+
Sbjct: 806 VHFCHRPS--------------------------LEGGAPLYDFGGMWGYVNNTLVRNPI 839

Query: 489 TNAQSCPAGYIPLNLFESLKVCVSLDYELGFKF-----SVP----FGGFFSCIMGNPLVN 539
           TN+ +CPAGY    L  + ++    D+EL   +     + P    FGG +  +   P+ N
Sbjct: 840 TNSANCPAGYADQRLLGTNRL----DHELHVCYRPHAANTPEMARFGGMYGTVQAAPVPN 895

Query: 540 SDTAKDVRAPSLKKCPGGF 558
             TA         +CP GF
Sbjct: 896 PATAT-------TECPSGF 907



 Score = 64.7 bits (156), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 46/208 (22%), Positives = 70/208 (33%), Gaps = 49/208 (23%)

Query: 398 EQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFC--------------- 442
             +N  TG  SCP G+    +L  TH   Y    C  + +   F                
Sbjct: 212 ATQNPATGAASCPEGFEQTQVL-GTHNVDYPLYFCMARASHWDFGGFIGTRNGGEPVLNP 270

Query: 443 ---KTVCEDVFRV------AKAEFRAYWCVAAGQVPDNSGLLFGGVFT----DKTINPMT 489
                 C D +           +   + C           L FGG++         NP T
Sbjct: 271 VTDTENCPDGYSRTQVLGTGAVDQPLHLCARPNWDGTEPELDFGGLWGFVNDTAVKNPYT 330

Query: 490 NAQSCPAGYIPLNLFESLKVCVSLDYEL---------GFKFSVPFGGFFSCIMGNPLVNS 540
           NAQ+CPAG+    +  ++      D+ L         G   ++PFGG +  + G+ + N 
Sbjct: 331 NAQNCPAGFTAQTVLGTM----GQDHNLHACYRPHVPGTGPTLPFGGMWGHVEGSQVPNP 386

Query: 541 DTAKDVRAPSLKKCPGGFSQHLAVISDG 568
            TA          CP GF+      + G
Sbjct: 387 VTAT-------ASCPKGFTPKQVFGTSG 407



 Score = 51.6 bits (122), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 38/179 (21%), Positives = 57/179 (31%), Gaps = 36/179 (20%)

Query: 395 QNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIF------------- 441
             L   N  TG  +CPPG     +L     +      C  +     F             
Sbjct: 549 NQLPVANPATGTTACPPGAVETQVLGTQGVDH-PVYYCMTRAPKWDFGGVFGYLNGGSPV 607

Query: 442 -----CKTVCEDVFRVAKAEFRA------YWCVAAGQVPDNSGLLFGGVF----TDKTIN 486
                  T C D +   + +  +      + C           L FGG++         N
Sbjct: 608 SNPATGATSCPDGYVQTQVQGSSTMDAPLFLCSRPSWDNAEPALDFGGMWGIVNGSWVNN 667

Query: 487 PMTNAQSCPAGYIPLNLFES------LKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVN 539
           P TN +SCPAG+  L +  +      L +C    +  G     PFGG +  +   P  N
Sbjct: 668 PYTNERSCPAGFAALKILGTAGQDSELHLCYRH-HAPGTVPPYPFGGMWGHVNDAPASN 725



 Score = 51.3 bits (121), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 39/191 (20%), Positives = 63/191 (32%), Gaps = 42/191 (21%)

Query: 370 DAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSR 429
           D       FGG++             +   KN  T   +CP G++   +L  T  + ++ 
Sbjct: 305 DGTEPELDFGGLW---------GFVNDTAVKNPYTNAQNCPAGFTAQTVL-GTMGQDHNL 354

Query: 430 LECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMT 489
             C +                            V         G ++G V   +  NP+T
Sbjct: 355 HACYRPH--------------------------VPGTGPTLPFGGMWGHVEGSQVPNPVT 388

Query: 490 NAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAP 549
              SCP G+ P  +F +  V  +L         + FGG F        +N+ T     A 
Sbjct: 389 ATASCPKGFTPKQVFGTSGVDAALHLCEPRSDVLDFGGAFG------RLNNGTLSPNPAT 442

Query: 550 SLKKCPGGFSQ 560
               CP G++Q
Sbjct: 443 GAASCPDGYTQ 453



 Score = 50.5 bits (119), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 41/240 (17%), Positives = 68/240 (28%), Gaps = 63/240 (26%)

Query: 369 CDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTH----- 423
           C  +   + FGGV+          L       N  TG  SCP GY    +   +      
Sbjct: 585 CMTRAPKWDFGGVF--------GYLNGGSPVSNPATGATSCPDGYVQTQVQGSSTMDAPL 636

Query: 424 --------------------------EEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEF 457
                                         +    ++ C        +     + +    
Sbjct: 637 FLCSRPSWDNAEPALDFGGMWGIVNGSWVNNPYTNERSCPAGFAALKILGTAGQDS---- 692

Query: 458 RAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPA----GYIPLNLFESLKVCVSL 513
             + C             FGG++      P +N  +       G+IP  +  +  +    
Sbjct: 693 ELHLCYRHHAPGTVPPYPFGGMWGHVNDAPASNPTTSTTSCPTGFIPRQILGTAHI---- 748

Query: 514 DY-----ELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDG 568
           D+     EL  K S+ FGG F         N+ T     A     CP G+++  A  + G
Sbjct: 749 DHPVYFCELPAK-SLDFGGAFG------FFNNGTLSPNPATGAASCPEGYTKTQAYGTHG 801



 Score = 46.3 bits (108), Expect = 0.004,   Method: Composition-based stats.
 Identities = 36/198 (18%), Positives = 59/198 (29%), Gaps = 50/198 (25%)

Query: 367 DSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEG 426
            S +     + FGG++             N   +N +T   +CP GY+   LL     + 
Sbjct: 812 PSLEGGAPLYDFGGMW---------GYVNNTLVRNPITNSANCPAGYADQRLLGTNRLDH 862

Query: 427 YSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKT-- 484
                        +  +    +   +A+                     FGG++      
Sbjct: 863 ELH----------VCYRPHAANTPEMAR---------------------FGGMYGTVQAA 891

Query: 485 --INPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDT 542
              NP T    CP+G+    +  +  V   L + +       FGGF   I G   V +  
Sbjct: 892 PVPNPATATTECPSGFEKTQVLGTSNVDHPLYFCMAHAPGWDFGGFIGSINGGETVPNPV 951

Query: 543 AKDVRAPSLKKCPGGFSQ 560
                      CP G  Q
Sbjct: 952 T------GTATCPDGHVQ 963


>UniRef50_Q23QV6 MAC/Perforin domain containing protein n=2 Tax=Tetrahymena
           thermophila SB210 RepID=Q23QV6_TETTH
          Length = 538

 Score = 63.2 bits (152), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 52/295 (17%), Positives = 104/295 (35%), Gaps = 33/295 (11%)

Query: 75  DGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKF--STE 132
           +  Y +P+ V+   QK   +   +  + S M+Y S+   S++ +   F    G+F  S +
Sbjct: 92  ERTYFVPNGVFLSQQKSCTMSFTARQVASMMDYTSSLEASVSIKGTFFG---GRFRASVD 148

Query: 133 FQRMKT--LQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGF-TKALMDICDQL-----EK 184
           +Q M+      + Q + +       ++ +    +      F    LMD  + +       
Sbjct: 149 YQDMQNDMESGEYQYIVSHSSC--SVFQLDLIDSPTYHAQFTNDILMDFQNLISIQGNSS 206

Query: 185 NQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF 244
           N    A Y        +GTHV++SV+ G+    +  + +S +    N    V+ASA I  
Sbjct: 207 NTEANAYYD---FFDKWGTHVVSSVNLGSLFGYKFQLLTSDIQSMNNQGIDVSASATI-- 261

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAID 304
               N +  T+   + +   ++  +       S G  P         W        + I 
Sbjct: 262 ---FNVRGRTNTQIEQNNLDNFSQSIQKWTSYSIGATPDVNNDPAN-WASQTLTKPMPIK 317

Query: 305 RAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPG--CTNVDSPN 357
            +  P H  +           +++         ++ YY    +    C+    PN
Sbjct: 318 SSITPYHEALN--IFTQGNNSILQS-----SQILQLYYKLRLYGNSYCSQRLLPN 365


>UniRef50_O76288 Apextrin n=4 Tax=Echinoida RepID=O76288_HELER
          Length = 491

 Score = 59.7 bits (143), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 50/240 (20%), Positives = 87/240 (36%), Gaps = 19/240 (7%)

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA 120
           R+ +LTY N KTT D +Y +PDEV    +  S     ++      +Y    S  +  + +
Sbjct: 67  RIFELTYDNGKTTNDNEYRVPDEVEFQQRSSSFTSKETDTFYGTKSYAKKLSHQVQADAS 126

Query: 121 ---LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGF---TKA 174
              +F+ V    S  ++ +         V +  Q       ++   +     GF    + 
Sbjct: 127 VEAVFASVKFSASHRYESISNDASTKGYVYSSEQTIQNFGHMRYLTSLAEHDGFEIAREF 186

Query: 175 LMDICDQLEKNQTK-MATYLAELLILNYGTHVITSVDAG---AALVQEDHVRSSFLLDNQ 230
            +D+CD      T     +L++     +GT V+T  D G       +ED  RSSF+ D  
Sbjct: 187 RIDVCDLPTTYATNTYMEFLSK-----WGTSVVTEADVGVRTGINSRED--RSSFVKDAS 239

Query: 231 NSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLE 290
              +   +  G     I +  +  D    +          T     + G   F   IT+ 
Sbjct: 240 TDMSNSVSVEGN--YKIFSASLSVDMDRFSQSASSEKKMGTEYTRYTIGSEEFNEPITIS 297


>UniRef50_UPI0000E49992 PREDICTED: similar to apextrin n=17 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E49992
          Length = 570

 Score = 59.3 bits (142), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 53/254 (20%), Positives = 93/254 (36%), Gaps = 24/254 (9%)

Query: 41  PVLEVLPGGGWDNLRNVDMGRVMDL-----TYTNCKTTEDGQYIIPDEVYTIPQKESNLE 95
            +LE  P GG      VD G ++       +Y   K + DG Y +PDEVY + +  +   
Sbjct: 42  NILEGNPEGGELGSGGVDPGLLVSRRIFELSYDESKVSSDGMYRVPDEVYFVSRDSAFTS 101

Query: 96  MNSEVLESWMNYQSTTSLSINTELALFS---RVNGKFSTEFQRMKTLQVKDQAVTTRVQ- 151
            +        +Y S  S  ++   +            S  ++ +        +V    Q 
Sbjct: 102 SSRTTFHGTESYASKLSAQVDVAGSYSGTFASAEFAASARYETISNRMASQGSVFFATQT 161

Query: 152 ---VRNRIY-TVKTTPTS-ELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVI 206
              + N  Y T    P S  L+ GF      +      N    A Y+    + ++GTHV+
Sbjct: 162 IQNLGNARYLTELAQPNSYALNNGFVSDACSLP-----NSYNEADYMQ--FLESWGTHVV 214

Query: 207 TSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDY 266
           T VD G  +        S  ++  ++Q + + SA  ++    +  +  +  S  S  +  
Sbjct: 215 TEVDLGTRVGTNYEESRSSFVEYASTQVSASLSASGSYAG-YSASIAVNMDSFNSGMESG 273

Query: 267 LS-NRTNSRVQSFG 279
            S   T S   + G
Sbjct: 274 SSFGSTYSS-YTVG 286


>UniRef50_B0R0K6 Novel protein n=10 Tax=Clupeocephala RepID=B0R0K6_DANRE
          Length = 517

 Score = 56.7 bits (135), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 52/264 (19%), Positives = 86/264 (32%), Gaps = 53/264 (20%)

Query: 126 NGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKN 185
            G  S   Q   +    D+A     ++    Y+ + T   ELS  F+K L  +       
Sbjct: 145 GGSRSDIAQFAHSQNTMDKATFALHEISCTYYSYRITDNPELSAEFSKHLQKLP------ 198

Query: 186 QTKMATYLAEL------LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTAS 239
               A Y A+        I  YGTH I  V  G  + +    R+        S+  +   
Sbjct: 199 ----AQYDAQTKPLYRRTIETYGTHYIRQVHLGGRVRRVTAFRTCLATLKGFSETDIKNC 254

Query: 240 AGIAFLNIVNF--KVETDYISQTSLTKD------YLSNRTNSRVQSFGGVPFYPGITLET 291
             +     + F     +     + + KD      Y    T+ + +  GG  ++P + L  
Sbjct: 255 LNVELKITLGFLPGNASLSNKCSQILKDNLSMGFYQGFMTH-KTEVLGGEKYFPDLVLSQ 313

Query: 292 --------WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYT 343
                   W   + N+   I  A  PLH  +     P         +S  ++ AV  Y  
Sbjct: 314 SPAEAYSNWMMSLHNNPDVISYAIFPLHHLVAD---PE--------VSSNLKIAVTEYIE 362

Query: 344 FNTH-------PGCTNVDSPNFNF 360
            N          GC+   +PN + 
Sbjct: 363 ENMISVDHKENQGCSQ--TPNLDH 384


>UniRef50_D0ZYB6 MAC/perforin domain protein n=1 Tax=Chlamydophila pneumoniae LPCoLN
           RepID=D0ZYB6_CHLPP
          Length = 818

 Score = 56.7 bits (135), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 36/230 (15%), Positives = 77/230 (33%), Gaps = 19/230 (8%)

Query: 118 ELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMD 177
           E +  S  +  FS EF  +K+   + +   T       +Y               K   +
Sbjct: 415 EASKDSAFSASFSYEF--VKSSTRESKNTVTHSTASRTLYI--LRQDCSYDPRALKVDDE 470

Query: 178 ICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVT 237
               +EK             +   GTH +TSV  G    Q   ++ S+L   +  +  ++
Sbjct: 471 FRYWVEKRLDAKNPDSLNAFVKEVGTHYVTSVTYGGIGFQV--LKMSYLQVEELEKEKIS 528

Query: 238 ---ASAGIAFLNIVNFKVE---TDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLET 291
              A+A     +  +   E   + Y S++S    +L       +Q          +  + 
Sbjct: 529 ISVAAASSLLKSKTSNATEKGYSSYQSESSAQTVFLGGTVLPDLQ-------QDKLDFKD 581

Query: 292 WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
           W + + N  + +  +   +   I P+  P     ++ +    +   + +Y
Sbjct: 582 WSESVPNEPIPLAISVSSITDLIIPELFPSEDAQVLSQKKSALGKVILNY 631


>UniRef50_P14222 Perforin-1 n=27 Tax=Mammalia RepID=PERF_HUMAN
          Length = 555

 Score = 55.9 bits (133), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 51/256 (19%), Positives = 76/256 (29%), Gaps = 37/256 (14%)

Query: 122 FSRVNGKFS--TEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDIC 179
              V G  S    F   KT Q +    T  V+ R   Y+     T  L   F +AL D+ 
Sbjct: 144 HVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECR--FYSFHVVHTPPLHPDFKRALGDLP 201

Query: 180 DQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTAS 239
                N +    YL   LI NYGTH I +V+ G  +     +R+  L     + N V   
Sbjct: 202 HHF--NASTQPAYLR--LISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDC 257

Query: 240 AGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSF--------GGVPFYPGITL-- 289
             +     +         ++    K      T S  Q++        GG        L  
Sbjct: 258 LTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFG 317

Query: 290 --------ETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
                     W   +      +D    PLH  +                 + +  A+  Y
Sbjct: 318 IQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQ----------DPRREALRRALSQY 367

Query: 342 YTFNT-HPGCTNVDSP 356
            T       C+    P
Sbjct: 368 LTDRARWRDCSRPCPP 383


>UniRef50_UPI00006A1994 UPI00006A1994 related cluster n=5 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI00006A1994
          Length = 520

 Score = 54.7 bits (130), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 69/392 (17%), Positives = 135/392 (34%), Gaps = 54/392 (13%)

Query: 25  ETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVM---------DLTYTNCKTTED 75
           + G+   + CK A  +P   +L G G D +     G  +         + T T C+   +
Sbjct: 5   KPGSP--EECKKASFVPGHTLL-GQGLDIVTMKKTGAFLLDMQIYQIPNKTCTLCENPYN 61

Query: 76  GQYIIPDEVYTI---PQKESNLEMNSEVLESWMNYQSTTSLSINTE-----------LAL 121
            + +    +  +   PQ      ++S ++ S ++  +  + ++  +           + +
Sbjct: 62  KKILEKLPISMVDWTPQTSCIRNIDSSLMRSKVSLANKEASNVQNDWKVGLDIPVKTVTV 121

Query: 122 FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQ 181
            + + G  S   +  ++  + DQ      ++    Y+ + +P + LS  F K L  + + 
Sbjct: 122 HTALAGSHSKLAEFAQSKTITDQYSFLSHELSCAFYSFRLSPDAPLSSYFAKDLRQLPN- 180

Query: 182 LEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAG 241
           L    TK   Y +   I  YGTH +T    G  + +   VR+  +  N    + V     
Sbjct: 181 LYNKNTKQ-KYRS--FISTYGTHYVTEAHVGGRIKEITAVRTCQVAMNSLKMSEVKDCLE 237

Query: 242 IAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQ---KGITN 298
           +     VN +          L+  +   + N+  Q   G  F+      T++      T 
Sbjct: 238 LEIAGSVNIEAA---DIGRGLSNKFCKEKANNINQ---GSDFHTSFNERTYEVKGGKATF 291

Query: 299 HLVAIDRAGLPLHFFIKPDKL---PGL------PGPLVKKL----SKTVETAVRHYYTFN 345
           +L      G P  F    + L   P L      P   + +L       V+ AV  Y    
Sbjct: 292 NLFDEKSGGKPEEFSAWMESLKTIPDLVAFSLSPIHNLVRLNGPQKNNVKKAVSDYINEK 351

Query: 346 THPGCTNVDSPNFNFQANMDDDSCDAKVTNFT 377
                        +  +   D SC    T ++
Sbjct: 352 ALR--MKCSCSGNSHPSRNGDCSCVCPATKYS 381


>UniRef50_C4JX95 Predicted protein n=1 Tax=Uncinocarpus reesii 1704
           RepID=C4JX95_UNCRE
          Length = 722

 Score = 54.7 bits (130), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 40/230 (17%), Positives = 71/230 (30%), Gaps = 37/230 (16%)

Query: 112 SLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGF 171
           S ++N     F+   G+FS  +     ++   +            Y      T    LGF
Sbjct: 281 SRTLNVGAD-FAGFGGEFSRTYDDSSKVETWKK------------YMATYHQTLIYRLGF 327

Query: 172 TKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQN 231
                      E       ++ AE +I  +GTH + S   G   +    + +SF      
Sbjct: 328 KDIDQAKTYLTETATEAFKSWSAEKIIHTFGTHYMISATFGGIRITSSSLDASFSGPETE 387

Query: 232 SQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLET 291
                                     S+    +  +S     R ++ GGV     +  + 
Sbjct: 388 ------------------LDANAKNSSKDQTVQQIMSKMELVRTRTIGGVADDSNV--QA 427

Query: 292 WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
           W+  + ++ V +D    P+   I    L G     VK     + TA + Y
Sbjct: 428 WRNSLYSNPVVVDYDIRPIWELIDDQNLAGQ----VKTQVNALLTAAQPY 473


>UniRef50_UPI00006CCD2A MAC/Perforin domain containing protein n=1 Tax=Tetrahymena
           thermophila RepID=UPI00006CCD2A
          Length = 387

 Score = 54.0 bits (128), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 41/263 (15%), Positives = 93/263 (35%), Gaps = 33/263 (12%)

Query: 100 VLESWMNYQSTTSLSINTELAL-FSRVNGK--FSTEFQRMKTLQVKDQAVTTRVQVRNRI 156
           V  S+ ++Q   + SI+ +  +    +     F+   + +     K+    T  Q     
Sbjct: 93  VYTSFTDFQKKLTESISIQGGIQIGDIKASLGFNHSLEEIYEKITKEGKSVTMSQSYWSK 152

Query: 157 YTVKTTPTS--ELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAA 214
           Y++  +P     L+  F +AL  + + ++  Q +        ++  YGTH ++S+  G  
Sbjct: 153 YSLTNSPAFLMPLNNQFKRALEYLNENVKIPQDQNGQTFYNQVVQAYGTHYVSSIVMGGT 212

Query: 215 LVQEDHVRSSFLL--DNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTN 272
                 + ++++   D Q  +N V         N +NF    +  ++ + +  Y  +  N
Sbjct: 213 AKILTLLNTTYVETHDFQEVKNQVNLEVNYIMSN-LNFDASFN-QTENTTSVVYQKDAEN 270

Query: 273 SRVQSFGGVPFYPGITLET-------WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGP 325
                   + F P ++          W+  +  +         P    I    L  L   
Sbjct: 271 Y-------IFFTPDLSHSKEEKAWDAWESRVPQN---------PQPVNITVSYLSDL-AS 313

Query: 326 LVKKLSKTVETAVRHYYTFNTHP 348
             K++ + +   + +Y      P
Sbjct: 314 SYKEVQQHLRDTIEYYLKNGDVP 336


>UniRef50_Q9U0J9 MAC/Perforin, putative n=8 Tax=Plasmodium RepID=Q9U0J9_PLAF7
          Length = 842

 Score = 52.8 bits (125), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 53/255 (20%), Positives = 88/255 (34%), Gaps = 30/255 (11%)

Query: 92  SNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQ 151
           S +E  +E   S  +Y  + S       + +   +   ST +        K    T  V+
Sbjct: 307 SRVESITEC-SSISDYTKSLSAEAKVSGSYWGIASFSASTGYSSFLHEVTKRSKKTFLVK 365

Query: 152 VRNRIYTVKTTP--TSELSLGFTKALMDI--------------CDQLEKNQTKMATYLAE 195
                YT+   P    + +  +  A+ ++               D  E+N+TK      E
Sbjct: 366 SNCVKYTIGLPPYIPWDKTTAYKNAVNELPAVFTGLDKESECPSDVYEENKTKS---NCE 422

Query: 196 LLILN------YGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVN 249
            + L       YGTH+I     G  + +  +V +S +   + +  +V A     F    +
Sbjct: 423 NVSLWMKFFDIYGTHIIYESQLGGKITKIINVSTSSIEQMKKNGVSVKAKIQAQF-GFGS 481

Query: 250 FKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFY---PGITLETWQKGITNHLVAIDRA 306
               TD  S  S   D  S   N ++   GG P         L  W K +TNH + I+  
Sbjct: 482 AGGSTDVNSSNSSANDEQSYDMNEQLIVIGGNPIKDVTKEENLFEWSKTVTNHPMPINIK 541

Query: 307 GLPLHFFIKPDKLPG 321
             P+      D L  
Sbjct: 542 LTPISDSFDSDDLKE 556


>UniRef50_UPI00006A16E1 Perforin 1 precursor (P1) (Lymphocyte pore forming protein) (PFP)
           (Cytolysin). n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI00006A16E1
          Length = 519

 Score = 52.4 bits (124), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 34/191 (17%), Positives = 71/191 (37%), Gaps = 24/191 (12%)

Query: 125 VNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEK 184
           + G  S   + +++   +D+    R Q++   Y+++ TP   LS  F K L D+    + 
Sbjct: 125 LAGSHSQLAKFVESKTNRDRYSFLRHQLKCLYYSLRLTPKPPLSNHFWKELQDLPKTYDT 184

Query: 185 NQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRS--SFLLDNQNS--QNTVTASA 240
             T+   Y     I  YGTH I+  + G  + +   +R+  + +        ++ ++  A
Sbjct: 185 G-TQQTFYR---FIRVYGTHYISQAEVGGQVSEVTAIRTCQATMDGLSLDELKDCLSLEA 240

Query: 241 GIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQ---KGIT 297
             +    +    E     + S               +  G  F+     + WQ     +T
Sbjct: 241 SASVTGKMEANAEAKTCKEMSQK-------------ATRGESFHKTFNEKDWQISGGKVT 287

Query: 298 NHLVAIDRAGL 308
             L++ D +  
Sbjct: 288 FDLLSFDVSKD 298


>UniRef50_UPI0000E48CEE PREDICTED: similar to apextrin n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E48CEE
          Length = 587

 Score = 52.0 bits (123), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 43/225 (19%), Positives = 75/225 (33%), Gaps = 48/225 (21%)

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKES-NLEMNSEVLESWMNYQSTTSLSINTEL 119
            ++ LTY   + T D +YI+PD+V   P+      E              T    I+ ++
Sbjct: 79  PILKLTYDENQLTSDREYIVPDQVLFSPRSSCVTTETQQTFYG-----TETYVEKISVDM 133

Query: 120 ALFSRVNGKFSTEF--------------QRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTS 165
               RV   FS                 +  + +  +D+ V    Q R     +      
Sbjct: 134 KESGRVKTIFSKHKFSKSSRYEEINRGVETNRYVYYEDRTVCNMGQARY-RSELAMYEQY 192

Query: 166 ELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSF 225
            L  GF  +   +   L  ++     +     I ++GTHV+T VD G             
Sbjct: 193 PLDTGFVYSACHLP--LTYDEETYMQF-----IDDWGTHVVTKVDLG------------- 232

Query: 226 LLDNQNSQNTVTASAGIA-FLNIVNFKVETDYISQTSLTKDYLSN 269
                 S++TV  +     F++    +VE     +T +   Y   
Sbjct: 233 ------SKSTVRFAESREDFVHFARTEVEGSVTFRTKIITGYRGA 271


>UniRef50_C3PWZ7 Putative uncharacterized protein n=2 Tax=Bacteroides sp. 9_1_42FAA
           RepID=C3PWZ7_9BACE
          Length = 491

 Score = 51.3 bits (121), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 29/159 (18%), Positives = 65/159 (40%), Gaps = 24/159 (15%)

Query: 178 ICDQLEKN-QTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTV 236
           +   L  N  + +  Y A+ ++  YGTHV+T++  G + +   + +S+ + +N  ++   
Sbjct: 173 LSRYLSSNFVSDLGKYSADQIVAKYGTHVLTNITVGGSYIA--YYKSAIIEENTGTEKKQ 230

Query: 237 TASAGIAF-LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFG--------------GV 281
           T SAG  + ++ V    +  + + T    +  ++     +Q  G              G 
Sbjct: 231 TVSAGAKYNMSKVGLDFDGTWSTTTITEANKKNSDWTCTIQCVGGTTSGTTITLAPNQGP 290

Query: 282 PFYPGITLETWQKGITN---HLVAID-RAGLPLHFFIKP 316
                I +  W + + +    LV +D  A  P++  +  
Sbjct: 291 T--TTINIGAWSQSVDDTHSRLVDVDWNATYPIYDLVSD 327


>UniRef50_B3L016 Sporozoite protein with MAC/Perforin domain n=1 Tax=Plasmodium
           knowlesi strain H RepID=B3L016_PLAKH
          Length = 844

 Score = 50.9 bits (120), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 60/352 (17%), Positives = 112/352 (31%), Gaps = 62/352 (17%)

Query: 43  LEVLPG-----GGWDNLRNVDMG--------------RVMDLTYTNCKTTEDGQYIIPDE 83
           L V PG      G+D+L    +G               +M+  ++N     D   + P  
Sbjct: 241 LSVFPGMYFAGIGYDSLFGNPLGESDSLTDPGYRGQIILMNWEFSNKGVANDLATLQPLN 300

Query: 84  VYTIPQKESNLEMNSEVL---ESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQ 140
            +    ++ N    +E +    S  +Y    +   +   +         ST +++     
Sbjct: 301 GW---IRKENACSRAESIKECSSISDYTKNLTAEASVSGSYMGFGAFSASTGYKKFLQET 357

Query: 141 VKDQAVTTRVQVRNRIYTVKTTPT--SELSLGFTKALMDI--------------CDQLEK 184
            K    T  ++     YTV   P    E +  F  A+  +               D  E+
Sbjct: 358 SKRTTKTYLIKSNCVKYTVGLPPYVHWEQTTAFKNAVDGLPPHFIGLEAESECASDVYEQ 417

Query: 185 NQTKM---ATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAG 241
            +T     + +        YGTH+I     G  + +   V ++ +   +    +V A   
Sbjct: 418 KKTSEECESVHAWITFFKTYGTHIIMEAQLGGKITKVVRVENTSVNQMKKDGISVKAQVK 477

Query: 242 IAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFY---PGITLETWQKGITN 298
             F    +    T+  S  S   +  +   + ++   GG P         L  W K ++ 
Sbjct: 478 AQF-GFASVGGSTNVSSDNSSKTNENNYEMSEQLVVIGGNPIKDVTKEENLYEWSKTVST 536

Query: 299 HLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY---YTFNTH 347
           +         P+   I    LP         L  + E A+ +Y   Y F+ H
Sbjct: 537 N---------PMP--INIRLLPISTIFESDDLKSSYEKALIYYTRLYGFSPH 577


>UniRef50_Q23I78 MAC/Perforin domain containing protein n=2 Tax=Tetrahymena
           thermophila SB210 RepID=Q23I78_TETTH
          Length = 681

 Score = 50.5 bits (119), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 44/252 (17%), Positives = 90/252 (35%), Gaps = 22/252 (8%)

Query: 44  EVLPGG-----GWD--NLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQ--KESNL 94
           E LPG      G+D   L N  +G+     +       +  + +  + Y +P   + + +
Sbjct: 20  ETLPGLDYIKSGYDGTKLLNDQLGQSKYPIFDLGPQNGESDFTVNGKTYKVPIMVQATQV 79

Query: 95  EMNSE-----VLESWMNYQSTTSLSINTELAL---FSRVNGKFSTEFQRMKTLQVKDQAV 146
            +  E     +  S+ ++Q   S SI+    L      ++   + E  +      ++   
Sbjct: 80  SLRKESQCEGIFYSFSDFQKKYSESISFSAGLGIENFSISLGINHELDQFHQEITQNNKA 139

Query: 147 TTRVQVRNRIYTVKTTPTS--ELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTH 204
            +  Q     Y++ T P     L+  F ++L  +    ++  T     +   +I ++GTH
Sbjct: 140 VSVSQSYWAQYSLTTAPAFLMPLNPMFKQSLDALNRMAKEPTTDTQQTIYNQVINSFGTH 199

Query: 205 VITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF-LNIVNFKVETDYISQTSLT 263
            +TS   G A      +  ++L      Q       GI F  N+  FK   +        
Sbjct: 200 YVTSAIMGGAAKIYTTLDQNYLKTVDIEQTK--TQIGINFSYNVFQFKFGFNSTDLAQKL 257

Query: 264 KDYLSNRTNSRV 275
            +     +N  +
Sbjct: 258 DENFKKNSNDII 269


>UniRef50_Q254S3 Phospholipase D endonuclease n=13 Tax=Chlamydiaceae
           RepID=Q254S3_CHLFF
          Length = 813

 Score = 50.5 bits (119), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 40/245 (16%), Positives = 84/245 (34%), Gaps = 23/245 (9%)

Query: 128 KFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTP---TSELSLGFTKALMDICDQLEK 184
             S  ++ ++    + +   T     + +Y +K        +L  GF   +     +L+ 
Sbjct: 416 SLSVTYEFVQKSTHQAKNTVTCSTAAHSLYILKEDEGNSQKKLDSGFQSWVET---KLKV 472

Query: 185 NQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF 244
           N         E  I  +GTH ITS   G    Q   +    + + Q+ + ++  +A  + 
Sbjct: 473 NDPSS----FEAFIQRFGTHYITSATYGGMGFQALKLSFQQVEELQSQKISLETAAANSL 528

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYP----GITLETWQKGITNHL 300
                 K       ++  +     + +++     GG          +    W + +    
Sbjct: 529 -----IKGSVSNQVESGYSSYDSKSSSHTVFL--GGTVLPSMKDEHLDFTEWSESVRLEP 581

Query: 301 VAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNF 360
           V I  + LP+   +  D  P      + +  K+++ AVR Y     H      +   F  
Sbjct: 582 VPIQVSLLPIADLLTTDFFPKENQDTLAQKKKSLKQAVRVYLK--KHKTSERKERAVFTS 639

Query: 361 QANMD 365
            AN++
Sbjct: 640 GANVN 644


>UniRef50_A0BCZ0 Chromosome undetermined scaffold_10, whole genome shotgun sequence
           n=2 Tax=Paramecium tetraurelia RepID=A0BCZ0_PARTE
          Length = 603

 Score = 50.1 bits (118), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 34/174 (19%), Positives = 64/174 (36%), Gaps = 11/174 (6%)

Query: 66  TYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTEL-ALFSR 124
           +Y+  + T DG++ IPD +  I +K       S V+++    Q+  S  I   L +    
Sbjct: 86  SYSKKQVTSDGRHKIPDNLNVITKKGCKYNFESFVIKNTEQIQNYMSSFIGVNLVSNIDI 145

Query: 125 VNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSEL---SLGFTKALMDICDQ 181
               F+   +     Q  +Q   T V         + T   EL      F   L  +   
Sbjct: 146 TPWAFTASSEFNHMQQKIEQTSATFVISMATCQIAQITQVPELAEFHQSFIDQLSALP-- 203

Query: 182 LEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT 235
           +E +  +   +L+     N+GTH  T +  G+ +     +  + + D    +  
Sbjct: 204 VEYSAPQYLEFLS-----NFGTHYATDIILGSKVGYVYTLPPAIVDDFDQKKFK 252


>UniRef50_Q8I2S3 MAC/Perforin, putative n=9 Tax=Plasmodium RepID=Q8I2S3_PLAF7
          Length = 821

 Score = 49.7 bits (117), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 93/504 (18%), Positives = 163/504 (32%), Gaps = 85/504 (16%)

Query: 20  DKPLGET---GTTGFQICKNALKLPVL-EVLPGGGWDNLRNVDMGRVMDLTYTNCKTTED 75
             P+G+       G++     L  P   E  P    DN  N++          +C  +E 
Sbjct: 251 GNPIGDPFLKVDPGYRDSIIKLTYPKSDEDYP----DNYMNINPNGSFVRNEISCNRSE- 305

Query: 76  GQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQR 135
                         KES +   SE  +       +   SI     LF   +     +   
Sbjct: 306 --------------KESEISTMSEYTKEL-----SVDASIGASYGLFGSFSASTGYKSVS 346

Query: 136 MKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAE 195
               + K +    +      + ++      +L+  F +A+  +      +  K  TY ++
Sbjct: 347 NTISKNKFRMFMLKSYCFKYVASLSQYSQWKLTDQFVRAISLLPSHF-NSLEKDGTYCSD 405

Query: 196 LLILN--------------------YGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT 235
               +                    +GTHV T +  G  + Q+  +  +       S  +
Sbjct: 406 EEFRDNRKSEKCGKSVTAWMYFFKNFGTHVSTLLHLGGKITQQVKISKNDYKAMTESGLS 465

Query: 236 VTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG-VPFYPG--ITLETW 292
           ++AS    F  +   K  T+  S  S   +  ++         GG   F P      E W
Sbjct: 466 ISASVSAGF-GLFKVKGSTNTESNESSNNESSTSSLEKETVIIGGTTIFDPNDPNNFEKW 524

Query: 293 QKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTN 352
            + I+ + + I     PL        LP        +LSK  E A+R Y + N  P    
Sbjct: 525 AESISENPMPIKGEYEPL-----SRILP-------TRLSKIYEEALRFYISVN-VPSNFG 571

Query: 353 VDSPNFNFQANMDDDSCDAKVTNFTFGG-VYQECTELSGDVLCQNLEQKNLLTGDFSCPP 411
             + N   Q N+ ++   A + + +  G V  EC E    +L  +L   N L        
Sbjct: 572 QITDNEIRQYNIKEELMKATMIHSSGTGLVVVECEEKQNFLLGFSLSIPNDL-------S 624

Query: 412 GYSPVHLLS--QTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAE---FRAYWCVAAG 466
                +L S  +  ++ YS++       +   CK      F              C    
Sbjct: 625 NLKDFYLNSCDEDSDKCYSKMSDNAYSYIFAMCKEEMIPFFEQKVKSGVGLLTLECSEKN 684

Query: 467 QVPDNSGLLFG-GVFTDKTINPMT 489
           QV     +LFG G+    T +P++
Sbjct: 685 QV-----ILFGFGISVLNTNDPIS 703


>UniRef50_A7RF42 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RF42_NEMVE
          Length = 967

 Score = 49.7 bits (117), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 40/208 (19%), Positives = 70/208 (33%), Gaps = 25/208 (12%)

Query: 80  IPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNG-------KFSTE 132
           +PD +      +++  M +    S   YQS          + F    G        FS+ 
Sbjct: 104 VPDTMNVHGIYDTSANMYT--FSSRSEYQSYLEKEAGVSGSYFGFYAGVKKAWGNSFSSN 161

Query: 133 FQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATY 192
            Q    L + D  V     VR  I+  +  P ++LS  F +  M++           A  
Sbjct: 162 VQSF--LSIFDIDV-----VRYEIFKDEVKP-ADLSQAFLQEFMNLPPSYFHPGAGQAY- 212

Query: 193 LAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKV 252
             +  IL +GTH I S   G  L      R +    +  ++   +      +  +     
Sbjct: 213 --QEFILRWGTHYIKSAKFGGEL----EFRKTLQGMSIATKEQASEVVEAEYKGLF-ASA 265

Query: 253 ETDYISQTSLTKDYLSNRTNSRVQSFGG 280
              Y S++       +  ++S V   GG
Sbjct: 266 GAKYESKSGQESKSENKFSSSSVVVQGG 293


>UniRef50_P07357 Complement component C8 alpha chain n=23 Tax=Amniota
           RepID=CO8A_HUMAN
          Length = 584

 Score = 48.9 bits (115), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 59/322 (18%), Positives = 96/322 (29%), Gaps = 59/322 (18%)

Query: 128 KFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQT 187
            F  E  +    +     + T+VQ  +            L  G  ++LM++ D  + N  
Sbjct: 274 SFLNELNKYNEKKFIFTRIFTKVQTAHFK---MRKDDIMLDEGMLQSLMELPD--QYNYG 328

Query: 188 KMATYLAELLILNYGTHVITSVDAGAA---LVQEDHVRSSFLLDNQNSQNT-VTASAGIA 243
             A +     I +YGTH ITS   G     ++  D  +   L        T    S GI 
Sbjct: 329 MYAKF-----INDYGTHYITSGSMGGIYEYILVIDKAKMESLGITSRDITTCFGGSLGIQ 383

Query: 244 FLNIVNFKVETDYI--------SQTSLTKDYLSNRTNSRVQSFGGVPF------YPGITL 289
           + + +N                      K        SRV+                IT 
Sbjct: 384 YEDKINVGGGLSGDHCKKFGGGKTERARKAMAVEDIISRVRGGSSGWSGGLAQNRSTITY 443

Query: 290 ETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY-YTFNTHP 348
            +W + +  + V ID    P+H  ++   L  L         + +  A+  Y   FN   
Sbjct: 444 RSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEAK-----RQNLRRALDQYLMEFNACR 498

Query: 349 GCTNVDSPNFNFQANMDDD-SCDAKVTNFTFGGVYQECTELSGD-----------VLCQN 396
            C     P FN    + +  SC  +    + G   ++                   +C+ 
Sbjct: 499 -C----GPCFNNGVPILEGTSCRCQCRLGSLGAACEQTQTEGAKADGSWSCWSSWSVCRA 553

Query: 397 LEQ--------KNLLTGDFSCP 410
             Q             G  SCP
Sbjct: 554 GIQERRRECDNPAPQNGGASCP 575


>UniRef50_C0YM92 Putative uncharacterized protein n=1 Tax=Chryseobacterium gleum
           ATCC 35910 RepID=C0YM92_9FLAO
          Length = 460

 Score = 48.6 bits (114), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 50/296 (16%), Positives = 93/296 (31%), Gaps = 63/296 (21%)

Query: 79  IIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA---LFSRVNGKFSTEFQR 135
           +I +  ++        E   E  E+  +Y    S  +N           ++  F++    
Sbjct: 88  LISENTFSQ-------EYTEEYGENAESYSKMVSTKVNATAGIPLFKKTLSVGFNSAVTT 140

Query: 136 MKTLQVKD--QAVTTRVQVRNRIYTVKTTPTSE-LSLGFTKALMDICDQLEKNQTKMATY 192
               + K    +    ++ +   +   T    + L+  F + L          QTK    
Sbjct: 141 NNKFEGKYIYGSYNLTIKQKRVRFNATTDMLGDYLTPEFAQDL----------QTKT--- 187

Query: 193 LAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKV 252
             + ++ +YGTHV   +  GA   + D +  +        +    A  G+       F V
Sbjct: 188 -PQQIVQDYGTHVAVDIYTGA---KLDVLFQAETRSQSRDR---AARIGVKVGMKDIFDV 240

Query: 253 ETDYISQTSLTK-DYLSNRTNSRVQSFGGVPFY------------PGITLETWQKGITNH 299
           +      TS +  +Y         ++ GG P              P I +  WQ      
Sbjct: 241 DVTNDVNTSESSMNYSKKLAY---KTRGGDPSKGLVGDLNLDQTNPKINISNWQNSSNAS 297

Query: 300 ---LVAIDRAGLP-LHFFIKPDKLPGLPGPLVKKLSKTVETAV---RHYYTFNTHP 348
              LV     GL  ++  +K             +L   V+  +   + Y  FNT P
Sbjct: 298 NSVLVDFGSNGLVIIYDLVKDAA-------KKAQLKAYVDQYLIDNKVYMEFNTIP 346


>UniRef50_B6Q8L9 Putative uncharacterized protein n=1 Tax=Penicillium marneffei ATCC
           18224 RepID=B6Q8L9_PENMQ
          Length = 784

 Score = 48.2 bits (113), Expect = 0.001,   Method: Composition-based stats.
 Identities = 30/238 (12%), Positives = 75/238 (31%), Gaps = 8/238 (3%)

Query: 90  KESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAV-TT 148
           K     + S +  +W +  ++ S+   ++    ++++ K +            ++    T
Sbjct: 243 KTVQFSVPSYLTMTWGSESTSFSIVGESKKEFTNKLSKKLNLGGDFFGFGGEFERTFDET 302

Query: 149 RVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITS 208
           R +   + Y  +       S+ F           +     M T+    ++ ++GTH    
Sbjct: 303 RTEETFKKYMARYNQEVVYSVSFKDEDNAAKYLSDDALVAMKTWTPAKIVASFGTHYTVQ 362

Query: 209 VDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLS 268
              G + +    + +    +   ++ +        F +           + TS T D   
Sbjct: 363 ATIGGSRILASSLDTR--DEFTETEMSTAIDLKAKFKDSKG-GDAGSINAGTSSTSDKSQ 419

Query: 269 NRTNSR----VQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL 322
               S       + GG        L +W++ +T +   I+    P+   +  D     
Sbjct: 420 KLFESLHTINTHTIGGTATDDNENLNSWRQSLTTNPALINYKLRPIEELVPADLTVEQ 477


>UniRef50_Q5TWT0 AGAP007256-PA n=4 Tax=Endopterygota RepID=Q5TWT0_ANOGA
          Length = 1171

 Score = 47.4 bits (111), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/108 (25%), Positives = 38/108 (35%), Gaps = 30/108 (27%)

Query: 367 DSCDAKVTNFTFG-GVYQECT-ELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHE 424
            SC+       FG G  + C+     +  C      N +TG +SCPPGY           
Sbjct: 633 PSCNEPCPKGFFGHGCMERCSGSAESNRTC------NPITGQYSCPPGYVG-PTCEHPCS 685

Query: 425 EGYSRLECKKKC---------------------TLKIFCKTVCEDVFR 451
            GY   +C+KKC                          C+TVCE ++ 
Sbjct: 686 SGYYGQDCQKKCPECRNGAECSHITGECQCTPGWKGPLCETVCEGMYY 733


>UniRef50_UPI000180CB36 PREDICTED: similar to complement component C6 n=3 Tax=Ciona
           intestinalis RepID=UPI000180CB36
          Length = 566

 Score = 46.6 bits (109), Expect = 0.003,   Method: Composition-based stats.
 Identities = 70/353 (19%), Positives = 124/353 (35%), Gaps = 71/353 (20%)

Query: 48  GGGWDNLRNVDMGRVMD-LTYT-NCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWM 105
           G G+D     ++G ++D   Y   C     G++   +E +  P    +    S+   S+ 
Sbjct: 207 GLGYDITLGEEIGTILDNRQYAGRCDRVRSGEH---EETFRKPANMQSFRFQSQATSSFT 263

Query: 106 --NYQSTT----SLSINTELALFSRVNGKFS---------TEFQRMKTLQVKDQAVTTRV 150
             +YQS+     S   N E  L +  +  FS         T+ +  KTL++ D+  ++ V
Sbjct: 264 AISYQSSKGFYESERSNMERKLQASASFSFSDMFGLSGSATKTRNSKTLRIIDRGTSSDV 323

Query: 151 QVRNRIYTVKTTPT------SELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTH 204
           +       +  +         +LS  F + L+++           A Y    LI +YGTH
Sbjct: 324 KYFRVFGEITLSRFRTIRRSFKLSHSFRQRLLELPQHY-----DYAKYSE--LIADYGTH 376

Query: 205 VITSVDAGAALVQEDHVRSSFLL----DNQNSQNTVTASAGIAFL-NIVNFKVETDYISQ 259
             +S   G           S L      ++  +N +T    + FL         T+  S 
Sbjct: 377 FYSSGVLGGRYEYIYRFSKSDLALSGLTDEEQKNCLTTETSMKFLKGFFGGSGGTNKCST 436

Query: 260 TSLTKDY-----------LSNRTNSRVQSFGGVPFY----PGITL-ETWQKGITNHLVAI 303
             L++ Y           +SN    +  +   + FY    P     E W + +      I
Sbjct: 437 NVLSRRYNGSFALAAKEAISNVIGGQSHTTSALTFYSSNGPNTAAYERWSRSVRVSPAII 496

Query: 304 DRAGLPLHFFIKP--DKLPGLPGPLVKKLSKTVETAVRHYY-TFNTHPGCTNV 353
           D       F + P    +P       +     +E A+  YY  +N +  CT  
Sbjct: 497 D-------FMLTPMSSVIPD------RNKQANMERALYDYYAKYNANK-CTGR 535


>UniRef50_B7FK63 Putative uncharacterized protein n=4 Tax=fabids RepID=B7FK63_MEDTR
          Length = 280

 Score = 46.3 bits (108), Expect = 0.004,   Method: Composition-based stats.
 Identities = 12/27 (44%), Positives = 16/27 (59%)

Query: 343 TFNTHPGCTNVDSPNFNFQANMDDDSC 369
             N  PGC +  SP ++  AN+DD SC
Sbjct: 244 ELNLVPGCIDPSSPLYDPMANVDDGSC 270


>UniRef50_B2AER0 Predicted CDS Pa_5_1800 n=1 Tax=Podospora anserina
           RepID=B2AER0_PODAN
          Length = 383

 Score = 46.3 bits (108), Expect = 0.004,   Method: Composition-based stats.
 Identities = 16/68 (23%), Positives = 31/68 (45%)

Query: 643 HGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDAT 702
              S+G+S G +AG+ +GVT+A+  V   A +  R+ ++     +E+ +        +  
Sbjct: 259 DAPSSGLSAGASAGMAVGVTVAVIAVGAGAFWLWRRKRRGGKLPVEDYQQPPTGPYGNGD 318

Query: 703 VLNGEEDP 710
           V      P
Sbjct: 319 VYAKVGAP 326


>UniRef50_UPI00005841B7 PREDICTED: similar to apextrin n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI00005841B7
          Length = 613

 Score = 45.9 bits (107), Expect = 0.006,   Method: Composition-based stats.
 Identities = 41/230 (17%), Positives = 84/230 (36%), Gaps = 20/230 (8%)

Query: 62  VMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL 121
           + +LTY   K ++D +Y +PDE   + +  +             +Y  T S  +    +L
Sbjct: 67  IFELTYDLGKKSKDNKYRVPDETEFLQRSSAFTTKEKSTFHGTKSYAKTLSSKVQESASL 126

Query: 122 ---FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGF---TKAL 175
              F+ V    S +++++   + K+  V    Q    + T++       +  F       
Sbjct: 127 DAVFASVKFAGSHDYKQISEDEKKEGYVYFTEQTIQNLGTIRYLDELARADQFEITRNFY 186

Query: 176 MDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSS----FLLDNQN 231
            D+C      +++   Y+    I  +GTHV+T +  G           S       + ++
Sbjct: 187 ADVCGLPVTYESQKKNYMD--FIDKWGTHVVTELQTGVRSGTTYRATRSSFVKLASEQRS 244

Query: 232 SQNTV-----TASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQ 276
              ++      ASA I+  N+  F    D  ++      Y + +  S   
Sbjct: 245 DSLSLEGHYKIASASISV-NMDKF--TEDKSAEKKFGSQYTTYKVGSETL 291


>UniRef50_Q4SUR7 Chromosome undetermined SCAF13844, whole genome shotgun sequence.
           (Fragment) n=7 Tax=Clupeocephala RepID=Q4SUR7_TETNG
          Length = 517

 Score = 45.5 bits (106), Expect = 0.007,   Method: Composition-based stats.
 Identities = 56/271 (20%), Positives = 96/271 (35%), Gaps = 37/271 (13%)

Query: 91  ESNLEMNSEVLESWMNYQSTTSLSINTELALFSR--VNGKFSTEFQRMKTLQVKDQAVTT 148
            S +  +S+ +    +   + S  +   L L     V G  S   Q   +   KD+   T
Sbjct: 97  SSKIFESSQEVMKEASSSLSVSWKVGLSLPLIGGAAVGGSHSRSSQFASSHSRKDKFSFT 156

Query: 149 RVQVRNRIYTVKTTPTSELSLGFTKALMDI-CDQLEKNQTKMATYLAELLILNYGTHVIT 207
              ++   YT +      LS  F ++L ++      KN +    +L+      YGTH I 
Sbjct: 157 THNLKCSYYTFRIHSRPPLSKEFEESLKNLPSTYDHKNTSAFTQFLS-----VYGTHFIR 211

Query: 208 SVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFL-NIVNFKVETDYI---SQTSLT 263
            V  G  +     +R+     +Q S  TV+    +    NI    V        +++S  
Sbjct: 212 RVRLGGHVNSITAIRTCQASMSQMSVQTVSNCLSVEAQANIKGVTVSAATQFCKTKSSKL 271

Query: 264 K---DYLSNRTNSRVQSFGG------VPFYPG--ITLETWQKGITNHLVAIDRAGLPLHF 312
           K    +    ++  ++  GG      V F        + W       L +I R    + +
Sbjct: 272 KTGATFRQAFSDRSIEVLGGDGDVGDVLFNSNGVAGFKKW-------LASIKRVPGLVWY 324

Query: 313 FIKPDKL--PGLPGPLVKKLSKTVETAVRHY 341
            I P  L  P  P      L +T+  A+ HY
Sbjct: 325 QISPLHLLVPDNPV-----LQETLSKAISHY 350


>UniRef50_Q64VU4 Putative uncharacterized protein n=2 Tax=Bacteroides fragilis
           RepID=Q64VU4_BACFR
          Length = 372

 Score = 45.1 bits (105), Expect = 0.008,   Method: Composition-based stats.
 Identities = 36/200 (18%), Positives = 72/200 (36%), Gaps = 50/200 (25%)

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
           +I +YGTHV+T +  G    +   +  S +  ++ +  TV A       N+ N  V+  Y
Sbjct: 181 IIQHYGTHVLTDITLGG---RITVLYRSSINTSKKTA-TVEAGCASGIKNMFNLSVDGHY 236

Query: 257 ISQTSLTKDYLSNRTNSRVQSFGGVPFY-------------PGITLETWQKGI-TNHLVA 302
             QT +  +          ++ GG P                 I + +WQ+    N++  
Sbjct: 237 D-QTLVKDNSEQEIVY---RTEGGDPSRALIGQLNYDSKNPSVIDISSWQQSCDDNNMTL 292

Query: 303 IDR---AGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFN 359
           +D    + +P++  +                   ++ AV +Y   +++            
Sbjct: 293 VDAEPGSLIPIYDLVSDMGKKEQ-----------LKLAVENYLKEHSYV----------- 330

Query: 360 FQANMDDDSCDAKVTNFTFG 379
              ++DD S    V N + G
Sbjct: 331 ---DIDDSSKGGAVRNNSRG 347


>UniRef50_C3ZTX2 Putative uncharacterized protein n=4 Tax=Branchiostoma floridae
           RepID=C3ZTX2_BRAFL
          Length = 1359

 Score = 43.6 bits (101), Expect = 0.028,   Method: Composition-based stats.
 Identities = 40/229 (17%), Positives = 79/229 (34%), Gaps = 25/229 (10%)

Query: 80  IPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTL 139
           +PD++      +S  +++S V E   +++           + +       S      K+ 
Sbjct: 271 VPDQMNVHGVYDS--DVSSRVFEGRESFRQFLQQKAGVSFSGWGFQGSVNSAWGGSSKSE 328

Query: 140 QVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLIL 199
           +    ++     +R  I+  +  PT +L+L F   L D     +      A  L E +I 
Sbjct: 329 KQMFMSLIEADIIRYEIFLDEVKPT-DLTLSF---LRDFLSLPKNFIIGKAK-LQEFIIR 383

Query: 200 NYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQ 259
            YGTH I S   G +      +  +       S  + + SA  ++  + +         +
Sbjct: 384 -YGTHYIKSAKFGGSF----QLYKTQEATKSESLESFSVSAQASYSGMFSAGAHYGRKEE 438

Query: 260 TSLTKDYLSNRTNSRVQSFGGVPFYPGI-----------TLETWQKGIT 297
           +       S+ T+  ++  GG     GI           T   W K + 
Sbjct: 439 SGSASSQKSSSTHLVIE--GGDQKVAGIVADFYTTSFKDTFTEWLKSVP 485


>UniRef50_Q2H1U9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
           RepID=Q2H1U9_CHAGB
          Length = 509

 Score = 42.4 bits (98), Expect = 0.056,   Method: Composition-based stats.
 Identities = 28/135 (20%), Positives = 42/135 (31%), Gaps = 4/135 (2%)

Query: 581 TGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMT 640
           T  SL P  LPP    P +   A  T +        +                       
Sbjct: 44  TSTSLPPAVLPPAISRPPLDD-ADATSLALAPVATTTAASTTLVVAETSTSTPSSSATAE 102

Query: 641 VIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKK---KEYQEIEEQESLVGSL 697
               DS  +SG   AGI +G    +  +  L        +K   +  Q+IE+ E + G  
Sbjct: 103 PSESDSGEISGAAKAGIVIGALAGILAIFVLVYLIFNSRRKKLARRRQQIEDDEKINGPF 162

Query: 698 ATDATVLNGEEDPSP 712
           A  A +       +P
Sbjct: 163 ADSAEIRPVPPAKAP 177


>UniRef50_A4QZP4 Predicted protein n=1 Tax=Magnaporthe grisea RepID=A4QZP4_MAGGR
          Length = 351

 Score = 42.4 bits (98), Expect = 0.058,   Method: Composition-based stats.
 Identities = 13/40 (32%), Positives = 26/40 (65%)

Query: 647 NGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKKKEYQE 686
           N +SGG  AGI +GV   + +++  A++  R+ ++K+ +E
Sbjct: 195 NELSGGAIAGIVVGVLAGVALIVAGALWFVRRERQKQQEE 234


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q2M385 Macrophage-expressed gene 1 protein n=18 Tax=Mam...   936   0.0  
UniRef50_UPI0000EBD8A9 PREDICTED: similar to macrophage expresse...   830   0.0  
UniRef50_Q7SXE0 Macrophage expressed 1 n=10 Tax=Clupeocephala Re...   812   0.0  
UniRef50_Q6RYF9 Macrophage expressed protein n=5 Tax=Eumetazoa R...   747   0.0  
UniRef50_UPI0000F2D8B8 PREDICTED: similar to Macrophage expresse...   728   0.0  
UniRef50_UPI0001796D85 PREDICTED: similar to Macrophage-expresse...   723   0.0  
UniRef50_B3F732 Macrophage expressed protein 1-like protein n=1 ...   698   0.0  
UniRef50_A7SEK6 Predicted protein (Fragment) n=1 Tax=Nematostell...   676   0.0  
UniRef50_Q4W1E5 Macrophage expressed protein n=1 Tax=Suberites d...   599   e-169
UniRef50_C4Q3P0 Expressed protein n=2 Tax=Schistosoma RepID=C4Q3...   528   e-148
UniRef50_Q2XSC0 Macrophage expressed protein (Fragment) n=1 Tax=...   385   e-105
UniRef50_Q80VB7 Mpeg1 protein (Fragment) n=1 Tax=Mus musculus Re...   359   3e-97
UniRef50_Q8I2S3 MAC/Perforin, putative n=9 Tax=Plasmodium RepID=...   268   4e-70
UniRef50_UPI00006A1994 UPI00006A1994 related cluster n=5 Tax=Xen...   207   1e-51
UniRef50_Q23QV5 MAC/Perforin domain containing protein n=1 Tax=T...   205   5e-51
UniRef50_Q23QV7 E1-E2 ATPase family protein n=4 Tax=Tetrahymena ...   203   2e-50
UniRef50_A0T3F5 Apextrin n=1 Tax=Acropora millepora RepID=A0T3F5...   190   1e-46
UniRef50_B3L016 Sporozoite protein with MAC/Perforin domain n=1 ...   189   2e-46
UniRef50_Q23QV6 MAC/Perforin domain containing protein n=2 Tax=T...   186   2e-45
UniRef50_D2WL87 MAC/perforin-and kringle-domains-containing prot...   183   2e-44
UniRef50_Q9U0J9 MAC/Perforin, putative n=8 Tax=Plasmodium RepID=...   181   1e-43
UniRef50_Q23I78 MAC/Perforin domain containing protein n=2 Tax=T...   166   3e-39
UniRef50_P07357 Complement component C8 alpha chain n=23 Tax=Amn...   164   9e-39
UniRef50_B0R0K6 Novel protein n=10 Tax=Clupeocephala RepID=B0R0K...   162   4e-38
UniRef50_UPI00006A16E1 Perforin 1 precursor (P1) (Lymphocyte por...   156   2e-36
UniRef50_O76288 Apextrin n=4 Tax=Echinoida RepID=O76288_HELER         156   3e-36
UniRef50_UPI0000E49992 PREDICTED: similar to apextrin n=17 Tax=S...   155   4e-36
UniRef50_Q1CW76 Putative uncharacterized protein n=1 Tax=Myxococ...   152   4e-35
UniRef50_Q5BVJ5 SJCHGC08097 protein (Fragment) n=1 Tax=Schistoso...   152   4e-35
UniRef50_P14222 Perforin-1 n=27 Tax=Mammalia RepID=PERF_HUMAN         152   5e-35
UniRef50_Q254S3 Phospholipase D endonuclease n=13 Tax=Chlamydiac...   150   3e-34
UniRef50_A0BCZ0 Chromosome undetermined scaffold_10, whole genom...   149   3e-34
UniRef50_C4JX95 Predicted protein n=1 Tax=Uncinocarpus reesii 17...   145   7e-33
UniRef50_B6Q8L9 Putative uncharacterized protein n=1 Tax=Penicil...   144   1e-32
UniRef50_UPI00006CCD2A MAC/Perforin domain containing protein n=...   144   1e-32
UniRef50_D0ZYB6 MAC/perforin domain protein n=1 Tax=Chlamydophil...   140   2e-31
UniRef50_UPI0000E48CEE PREDICTED: similar to apextrin n=1 Tax=St...   137   2e-30
UniRef50_A7RF42 Predicted protein n=1 Tax=Nematostella vectensis...   130   2e-28
UniRef50_C0YM92 Putative uncharacterized protein n=1 Tax=Chryseo...   105   8e-21
UniRef50_C3PWZ7 Putative uncharacterized protein n=2 Tax=Bactero...    91   1e-16

Sequences not found previously or not previously below threshold:

UniRef50_Q32N46 LOC495232 protein n=3 Tax=Xenopus RepID=Q32N46_X...   135   5e-30
UniRef50_UPI00005841B7 PREDICTED: similar to apextrin n=1 Tax=St...   135   5e-30
UniRef50_B5X1M0 Perforin-1 n=2 Tax=Salmoninae RepID=B5X1M0_SALSA      129   4e-28
UniRef50_UPI000176082E PREDICTED: similar to perforin 1 (pore fo...   129   5e-28
UniRef50_Q4SUR7 Chromosome undetermined SCAF13844, whole genome ...   127   2e-27
UniRef50_B5X3H3 Perforin-1 n=1 Tax=Salmo salar RepID=B5X3H3_SALSA     126   4e-27
UniRef50_Q7ZZH8 Perforin n=7 Tax=Clupeocephala RepID=Q7ZZH8_PAROL     124   1e-26
UniRef50_A7AVA8 MAC/perforin domain containing protein n=1 Tax=B...   124   1e-26
UniRef50_Q4N9F0 Putative uncharacterized protein n=2 Tax=Theiler...   123   2e-26
UniRef50_UPI00016E2000 UPI00016E2000 related cluster n=1 Tax=Tak...   119   3e-25
UniRef50_A1E348 Perforin-like protein 1 n=4 Tax=Toxoplasma gondi...   117   1e-24
UniRef50_A7RF41 Predicted protein n=1 Tax=Nematostella vectensis...   117   2e-24
UniRef50_Q4Y6N1 Putative uncharacterized protein n=2 Tax=Plasmod...   117   2e-24
UniRef50_Q6DBQ7 Complement component 8, alpha polypeptide n=10 T...   116   3e-24
UniRef50_A7AUQ4 Mac/perforin domain containing protein n=1 Tax=B...   114   1e-23
UniRef50_B6KDF3 Membrane-attack complex / perforin domain-contai...   112   4e-23
UniRef50_B3LCG2 MAC/Perforin domain, putative n=4 Tax=Plasmodium...   110   2e-22
UniRef50_UPI0001924DF1 PREDICTED: similar to conserved hypotheti...   110   2e-22
UniRef50_C3ZX08 Putative uncharacterized protein n=1 Tax=Branchi...   107   2e-21
UniRef50_Q4UDM0 Hypothetical membrane protein, conserved n=2 Tax...   106   2e-21
UniRef50_Q4U9X5 MAC/perforin, putative n=2 Tax=Theileria RepID=Q...   106   3e-21
UniRef50_C3YX95 Putative uncharacterized protein n=3 Tax=Branchi...   104   8e-21
UniRef50_Q498V9 LOC570832 protein (Fragment) n=9 Tax=Clupeocepha...   103   2e-20
UniRef50_UPI00006A16E2 Perforin 1 precursor (P1) (Lymphocyte por...   103   2e-20
UniRef50_UPI000180CB36 PREDICTED: similar to complement componen...   103   3e-20
UniRef50_UPI0000E46B2F PREDICTED: similar to apextrin, partial n...   101   9e-20
UniRef50_UPI0000521199 PREDICTED: similar to complement componen...   101   1e-19
UniRef50_B1NM18 Complement component 8 alpha polypeptide n=1 Tax...   101   1e-19
UniRef50_Q9PVW7 Complement component C8 beta chain n=11 Tax=Clup...   100   4e-19
UniRef50_UPI000180B7EE PREDICTED: similar to HyTSR1 protein n=4 ...    99   6e-19
UniRef50_Q8I5P0 MAC/Perforin, putative n=1 Tax=Plasmodium falcip...    98   8e-19
UniRef50_UPI0001924D14 PREDICTED: similar to apextrin n=4 Tax=Hy...    97   3e-18
UniRef50_P07358 Complement component C8 beta chain n=25 Tax=Eute...    96   4e-18
UniRef50_P13671 Complement component C6 n=27 Tax=Tetrapoda RepID...    96   6e-18
UniRef50_D0FYH7 Complement component C6 n=1 Tax=Mustelus manazo ...    94   2e-17
UniRef50_A7AM24 Predicted protein n=1 Tax=Babesia bovis RepID=A7...    94   2e-17
UniRef50_C3YIK1 Putative uncharacterized protein n=1 Tax=Branchi...    94   2e-17
UniRef50_P02748 Complement component C9b n=13 Tax=Theria RepID=C...    93   3e-17
UniRef50_UPI000180B791 PREDICTED: similar to thrombospondin type...    92   9e-17
UniRef50_B5X0R1 Complement component C7 n=8 Tax=Euteleostei RepI...    91   1e-16
UniRef50_A7RN26 Predicted protein (Fragment) n=1 Tax=Nematostell...    90   2e-16
UniRef50_B0JZ32 C9 protein (Fragment) n=5 Tax=Tetrapoda RepID=B0...    90   3e-16
UniRef50_A7AT92 Mac/perforin domain containing membrane protein ...    90   3e-16
UniRef50_C3ZTX2 Putative uncharacterized protein n=4 Tax=Branchi...    90   4e-16
UniRef50_P10643 Complement component C7 n=24 Tax=Tetrapoda RepID...    88   1e-15
UniRef50_Q969A3 Complement component C6 n=1 Tax=Branchiostoma be...    88   1e-15
UniRef50_B0S6X4 Novel protein similar to vertebrate complement c...    87   2e-15
UniRef50_UPI000180B792 PREDICTED: similar to complement componen...    87   2e-15
UniRef50_UPI0000E47361 PREDICTED: similar to apextrin, partial n...    87   2e-15
UniRef50_D2UX64 Predicted protein n=1 Tax=Naegleria gruberi RepI...    87   2e-15
UniRef50_B9X257 Similar to terminal complement component n=1 Tax...    86   4e-15
UniRef50_A7AT97 Mac/perforin domain containing protein n=1 Tax=B...    85   9e-15
UniRef50_UPI000196958C hypothetical protein BACCELL_01585 n=1 Ta...    85   1e-14
UniRef50_Q4T1D8 Chromosome undetermined SCAF10660, whole genome ...    85   1e-14
UniRef50_UPI000194DE7A PREDICTED: similar to complement protein ...    84   2e-14
UniRef50_UPI0001555301 PREDICTED: similar to Complement componen...    83   4e-14
UniRef50_Q4UAZ8 Perforin-related protein, putative n=4 Tax=Theil...    83   4e-14
UniRef50_B1ASJ8 Complement component 8, beta subunit n=3 Tax=Mur...    83   5e-14
UniRef50_UPI00015558C0 PREDICTED: similar to Perforin-1 precurso...    81   1e-13
UniRef50_Q6PFT2 Complement component 6 n=9 Tax=Clupeocephala Rep...    81   1e-13
UniRef50_P79755 Complement component C9 n=10 Tax=Euteleostei Rep...    81   2e-13
UniRef50_A5CTM8 Putative uncharacterized protein n=1 Tax=Claviba...    80   2e-13
UniRef50_D1B2B8 Membrane attack complex component/perforin/compl...    80   4e-13
UniRef50_C3ZX09 Putative uncharacterized protein n=1 Tax=Branchi...    80   5e-13
UniRef50_Q4U9X4 MAC/perforin, putative n=2 Tax=Theileria RepID=Q...    78   9e-13
UniRef50_Q6H964 Complement component C6 n=10 Tax=Clupeocephala R...    78   1e-12
UniRef50_D0FYI7 Complement component C8 beta subunit n=1 Tax=Chi...    78   2e-12
UniRef50_UPI0001556468 PREDICTED: similar to MAC/perforin, putat...    78   2e-12
UniRef50_C3ZKF3 Putative uncharacterized protein n=1 Tax=Branchi...    78   2e-12
UniRef50_A7V074 Putative uncharacterized protein n=2 Tax=Bactero...    77   3e-12
UniRef50_C3ZT44 Putative uncharacterized protein n=3 Tax=Branchi...    76   6e-12
UniRef50_Q4T0Y8 Chromosome 12 SCAF10787, whole genome shotgun se...    76   6e-12
UniRef50_C3ZT46 Putative uncharacterized protein n=3 Tax=Branchi...    75   1e-11
UniRef50_Q117U3 Membrane attack complex component/perforin/compl...    74   2e-11
UniRef50_Q6TNF0 Complement component C9 n=3 Tax=Clupeocephala Re...    73   5e-11
UniRef50_D2I7R7 Putative uncharacterized protein (Fragment) n=2 ...    73   5e-11
UniRef50_C3Z0X4 Putative uncharacterized protein n=2 Tax=Branchi...    72   8e-11
UniRef50_C3ZXW6 Putative uncharacterized protein n=2 Tax=Branchi...    72   8e-11
UniRef50_UPI0000F2BC28 PREDICTED: similar to complement componen...    72   1e-10
UniRef50_C3XW28 Putative uncharacterized protein n=3 Tax=Branchi...    70   4e-10
UniRef50_C2FV94 Putative uncharacterized protein (Fragment) n=1 ...    69   7e-10
UniRef50_A7SG86 Predicted protein n=3 Tax=Nematostella vectensis...    69   7e-10
UniRef50_A8GEE9 Membrane attack complex component/perforin/compl...    69   7e-10
UniRef50_Q64VU4 Putative uncharacterized protein n=2 Tax=Bactero...    68   1e-09
UniRef50_C3ZSP3 Putative uncharacterized protein n=1 Tax=Branchi...    68   2e-09
UniRef50_UPI000155C7F4 PREDICTED: similar to complement componen...    67   3e-09
UniRef50_C8V7Z0 SpoC1-C1C protein [Source:UniProtKB/TrEMBL;Acc:Q...    66   3e-09
UniRef50_C3YP09 Putative uncharacterized protein n=8 Tax=Deutero...    66   5e-09
UniRef50_C3ZTY9 Putative uncharacterized protein n=1 Tax=Branchi...    66   6e-09
UniRef50_Q5W9E8 Pleurotolysin B n=3 Tax=Agaricales RepID=Q5W9E8_...    66   6e-09
UniRef50_A3XM68 Guanosine polyphosphate pyrophosphohydrolase/syn...    66   6e-09
UniRef50_C3YVU9 Putative uncharacterized protein n=2 Tax=Branchi...    66   6e-09
UniRef50_UPI0000E466A5 PREDICTED: similar to apextrin n=2 Tax=St...    65   7e-09
UniRef50_C1MJU5 Predicted protein n=1 Tax=Micromonas pusilla CCM...    65   8e-09
UniRef50_B8A565 Complement component 9 n=5 Tax=Cyprinidae RepID=...    65   1e-08
UniRef50_C6IIH6 Putative uncharacterized protein n=1 Tax=Bactero...    65   1e-08
UniRef50_A7AM15 Putative uncharacterized protein n=1 Tax=Babesia...    65   1e-08
UniRef50_C3ZKZ8 Putative uncharacterized protein n=3 Tax=Branchi...    64   2e-08
UniRef50_D1K377 Putative uncharacterized protein n=1 Tax=Bactero...    63   4e-08
UniRef50_D2E8B6 ORF65 n=1 Tax=Anguillid herpesvirus 1 RepID=D2E8...    63   4e-08
UniRef50_C3ZSC8 Putative uncharacterized protein n=3 Tax=Branchi...    62   8e-08
UniRef50_A7RGY2 Predicted protein n=1 Tax=Nematostella vectensis...    61   1e-07
UniRef50_B6H8Y2 Pc16g03220 protein n=1 Tax=Penicillium chrysogen...    60   2e-07
UniRef50_Q54I05 Putative uncharacterized protein n=1 Tax=Dictyos...    60   2e-07
UniRef50_Q2GRU1 Putative uncharacterized protein n=1 Tax=Chaetom...    60   3e-07
UniRef50_UPI0000E45FB2 PREDICTED: similar to apextrin n=1 Tax=St...    60   3e-07
UniRef50_Q23JJ5 MAC/Perforin domain containing protein n=12 Tax=...    60   3e-07
UniRef50_UPI000180CCD0 PREDICTED: similar to complement componen...    60   3e-07
UniRef50_A7BVI9 Membrane attack complex component/perforin/compl...    60   3e-07
UniRef50_A2TUN8 Guanosine polyphosphate pyrophosphohydrolase/syn...    59   6e-07
UniRef50_C3ZP97 Putative uncharacterized protein n=2 Tax=Branchi...    59   7e-07
UniRef50_Q94J22 Os01g0748900 protein n=2 Tax=Magnoliophyta RepID...    59   8e-07
UniRef50_D2VPS9 Predicted protein n=2 Tax=Naegleria gruberi RepI...    58   1e-06
UniRef50_A5B4D4 Putative uncharacterized protein n=1 Tax=Vitis v...    58   1e-06
UniRef50_D2VJY2 Predicted protein n=1 Tax=Naegleria gruberi RepI...    57   2e-06
UniRef50_B9IGR8 Predicted protein n=10 Tax=Embryophyta RepID=B9I...    57   3e-06
UniRef50_C3ZA36 Putative uncharacterized protein n=1 Tax=Branchi...    56   3e-06
UniRef50_A3YG19 Putative uncharacterized protein n=1 Tax=Marinom...    56   4e-06
UniRef50_C3ZUI3 Putative uncharacterized protein n=2 Tax=Branchi...    56   4e-06
UniRef50_B3L1A1 Putative uncharacterized protein n=1 Tax=Plasmod...    56   5e-06
UniRef50_C3YBL0 Putative uncharacterized protein n=3 Tax=Branchi...    56   6e-06
UniRef50_C6I3S0 Putative uncharacterized protein n=3 Tax=Bactero...    55   8e-06
UniRef50_Q4MYN1 Putative uncharacterized protein n=2 Tax=Theiler...    55   1e-05
UniRef50_B6VN53 Putative uncharacterized protein n=2 Tax=Photorh...    55   1e-05
UniRef50_D2VN11 Predicted protein n=1 Tax=Naegleria gruberi RepI...    55   1e-05
UniRef50_UPI00005853E1 PREDICTED: similar to apextrin, partial n...    54   1e-05
UniRef50_B9HDI2 Predicted protein n=1 Tax=Populus trichocarpa Re...    54   1e-05
UniRef50_Q7RHP1 Putative uncharacterized protein PY03943 n=3 Tax...    54   1e-05
UniRef50_Q8IB29 MAC/Perforin, putative n=5 Tax=Plasmodium RepID=...    54   2e-05
UniRef50_Q940R0 At1g29690/F15D2_24 n=1 Tax=Arabidopsis thaliana ...    54   2e-05
UniRef50_D2VHQ5 Predicted protein n=1 Tax=Naegleria gruberi RepI...    54   2e-05
UniRef50_C3YPJ1 Putative uncharacterized protein n=1 Tax=Branchi...    54   2e-05
UniRef50_A7S1Q6 Predicted protein n=1 Tax=Nematostella vectensis...    54   2e-05
UniRef50_B6TJS6 MAC/Perforin domain containing protein n=4 Tax=M...    53   3e-05
UniRef50_A7S919 Predicted protein (Fragment) n=1 Tax=Nematostell...    53   3e-05
UniRef50_Q9SGN6 F3M18.18 n=37 Tax=Magnoliophyta RepID=Q9SGN6_ARATH     53   4e-05
UniRef50_D1HA82 Whole genome shotgun sequence of line PN40024, s...    53   5e-05
UniRef50_B2AFJ9 Predicted CDS Pa_5_11830 n=1 Tax=Podospora anser...    53   6e-05
UniRef50_C7XDV3 Predicted protein n=1 Tax=Parabacteroides sp. D1...    52   8e-05
UniRef50_Q9LQV3 F10B6.18 n=3 Tax=rosids RepID=Q9LQV3_ARATH             52   1e-04
UniRef50_UPI00006A1BED UPI00006A1BED related cluster n=1 Tax=Xen...    51   1e-04
UniRef50_UPI0001983FB0 PREDICTED: hypothetical protein n=2 Tax=V...    51   1e-04
UniRef50_D1IBJ9 Whole genome shotgun sequence of line PN40024, s...    51   1e-04
UniRef50_Q23JP5 MAC/Perforin domain containing protein n=13 Tax=...    51   1e-04
UniRef50_B3L199 MAC/perforin, putative n=1 Tax=Plasmodium knowle...    51   2e-04
UniRef50_D2UX93 Membrane-attack complex/perforin domain-containi...    51   2e-04
UniRef50_C3ZMB3 Putative uncharacterized protein n=5 Tax=Branchi...    51   2e-04
UniRef50_UPI0001554DA0 PREDICTED: similar to Complement componen...    51   2e-04
UniRef50_UPI0001969EAD hypothetical protein BACCELL_05502 n=1 Ta...    50   3e-04
UniRef50_A1CVR0 Putative uncharacterized protein n=1 Tax=Neosart...    49   6e-04
UniRef50_B9N3I8 Predicted protein (Fragment) n=1 Tax=Populus tri...    49   8e-04
UniRef50_A5K5Q5 MAC/Perforin domain containing protein n=1 Tax=P...    48   0.001
UniRef50_UPI000023E855 hypothetical protein FG01821.1 n=1 Tax=Gi...    48   0.001
UniRef50_A6G7F3 Hemopexin n=1 Tax=Plesiocystis pacifica SIR-1 Re...    48   0.001
UniRef50_B3C689 Putative uncharacterized protein n=4 Tax=Bactero...    48   0.002
UniRef50_Q8I497 Delta2 protein n=1 Tax=Cupiennius salei RepID=Q8...    47   0.002
UniRef50_C3ZVU2 Putative uncharacterized protein n=1 Tax=Branchi...    47   0.002
UniRef50_D1JPJ4 Putative uncharacterized protein n=2 Tax=Bactero...    47   0.003
UniRef50_C6QX82 Putative lipoprotein n=2 Tax=Bacteria RepID=C6QX...    47   0.003
UniRef50_UPI000186DD19 Neurogenic locus protein delta precursor,...    46   0.005
UniRef50_C4JS74 Predicted protein n=1 Tax=Uncinocarpus reesii 17...    46   0.005
UniRef50_Q4SU28 Chromosome undetermined SCAF14025, whole genome ...    46   0.006
UniRef50_D2VK21 Predicted protein n=1 Tax=Naegleria gruberi RepI...    46   0.006
UniRef50_A0ZVQ7 Delta n=2 Tax=Entelegynae RepID=A0ZVQ7_PARTP           46   0.007
UniRef50_Q7PR44 AGAP003027-PA (Fragment) n=1 Tax=Anopheles gambi...    45   0.010
UniRef50_Q5RGG6 Novel protein similar to vertebrate delta-like 4...    45   0.012
UniRef50_B7PT11 LIN-12 protein, putative n=2 Tax=Coelomata RepID...    45   0.013
UniRef50_C3YG94 Putative uncharacterized protein n=1 Tax=Branchi...    44   0.014
UniRef50_Q76B58 Protein FAM5C n=21 Tax=Euteleostomi RepID=FAM5C_...    44   0.016
UniRef50_B5B3T0 Delta protein n=2 Tax=Deuterostomia RepID=B5B3T0...    44   0.017
UniRef50_B3RTL5 Putative uncharacterized protein n=1 Tax=Trichop...    44   0.025
UniRef50_Q61483 Delta-like protein 1 n=31 Tax=Euteleostomi RepID...    43   0.033
UniRef50_Q2TXD5 Predicted protein n=2 Tax=Aspergillus RepID=Q2TX...    43   0.037
UniRef50_B8NXE5 Putative uncharacterized protein n=1 Tax=Aspergi...    42   0.076

>UniRef50_Q2M385 Macrophage-expressed gene 1 protein n=18 Tax=Mammalia
           RepID=MPEG1_HUMAN
          Length = 716

 Score =  936 bits (2418), Expect = 0.0,   Method: Composition-based stats.
 Identities = 542/716 (75%), Positives = 621/716 (86%), Gaps = 3/716 (0%)

Query: 1   MNSFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMG 60
           MN+F A +L W   A A++ KP GE    G Q CKNALKLPVLEVLPGGGWDNLRNVDMG
Sbjct: 1   MNNFRATILFWAAAAWAKSGKPSGEMDEVGVQKCKNALKLPVLEVLPGGGWDNLRNVDMG 60

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA 120
           RVM+LTY+NC+TTEDGQYIIPDE++TIPQK+SNLEMNSE+LESW NYQS+TS SINTEL+
Sbjct: 61  RVMELTYSNCRTTEDGQYIIPDEIFTIPQKQSNLEMNSEILESWANYQSSTSYSINTELS 120

Query: 121 LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICD 180
           LFS+VNGKFSTEFQRMKTLQVKDQA+TTRVQVRN +YTVK  PT ELS GF K L+DI D
Sbjct: 121 LFSKVNGKFSTEFQRMKTLQVKDQAITTRVQVRNLVYTVKINPTLELSSGFRKELLDISD 180

Query: 181 QLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASA 240
           +LE NQT+MATYLAELL+LNYGTHV TSVDAGAAL+QEDH+R+SFL D+Q+S++ VTASA
Sbjct: 181 RLENNQTRMATYLAELLVLNYGTHVTTSVDAGAALIQEDHLRASFLQDSQSSRSAVTASA 240

Query: 241 GIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHL 300
           G+AF N VNFK E +Y SQ  LTK YLSNRTNSRVQS GGVPFYPGITL+ WQ+GITNHL
Sbjct: 241 GLAFQNTVNFKFEENYTSQNVLTKSYLSNRTNSRVQSIGGVPFYPGITLQAWQQGITNHL 300

Query: 301 VAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNF 360
           VAIDR+GLPLHFFI P+ LP LPGPLVKK+SKTVETAV+ YYTFNT+PGCT+++SPNFNF
Sbjct: 301 VAIDRSGLPLHFFINPNMLPDLPGPLVKKVSKTVETAVKRYYTFNTYPGCTDLNSPNFNF 360

Query: 361 QANMDDDSCDAKVTNFTFGGVYQECTELSGD---VLCQNLEQKNLLTGDFSCPPGYSPVH 417
           QAN DD SC+ K+TNF+FGGVYQECT+LSG+   +LCQ LEQKN LTGDFSCP GYSPVH
Sbjct: 361 QANTDDGSCEGKMTNFSFGGVYQECTQLSGNRDVLLCQKLEQKNPLTGDFSCPSGYSPVH 420

Query: 418 LLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFG 477
           LLSQ HEEGY+ LEC +KCTL +FCKTVCEDVF+VAKAEFRA+WCVA+ QVP+NSGLLFG
Sbjct: 421 LLSQIHEEGYNHLECHRKCTLLVFCKTVCEDVFQVAKAEFRAFWCVASSQVPENSGLLFG 480

Query: 478 GVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPL 537
           G+F+ K+INPMTNAQSCPAGY PL LFE+LKVCVS DYELG +F+VPFGGFFSC +GNPL
Sbjct: 481 GLFSSKSINPMTNAQSCPAGYFPLRLFENLKVCVSQDYELGSRFAVPFGGFFSCTVGNPL 540

Query: 538 VNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP 597
           V+   ++D+ APSLKKCPGGFSQH A+ISDGCQVSYCVK+G+FTGGSL P RLPP+T+PP
Sbjct: 541 VDPAISRDLGAPSLKKCPGGFSQHPALISDGCQVSYCVKSGLFTGGSLPPARLPPFTRPP 600

Query: 598 LMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGI 657
           LMSQ ATNTVIVTNSE ARSWIKD QT+QW+LGEP+ELRRAM VIHGD  G+SGG AAG+
Sbjct: 601 LMSQAATNTVIVTNSENARSWIKDSQTHQWRLGEPIELRRAMNVIHGDGGGLSGGAAAGV 660

Query: 658 TLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 713
           T+GVT  L +VITLAIYGTRK+KKK YQ IEE++SLV   A        E+  SPA
Sbjct: 661 TVGVTTILAVVITLAIYGTRKFKKKAYQAIEERQSLVPGTAATGDTTYQEQGQSPA 716


>UniRef50_UPI0000EBD8A9 PREDICTED: similar to macrophage expressed gene 1 n=1 Tax=Bos
           taurus RepID=UPI0000EBD8A9
          Length = 753

 Score =  830 bits (2143), Expect = 0.0,   Method: Composition-based stats.
 Identities = 264/716 (36%), Positives = 393/716 (54%), Gaps = 30/716 (4%)

Query: 23  LGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPD 82
             + G  GFQ CK  L + VL  LPG GWDNLRN+++G V+   Y+ C TTEDG+Y+IPD
Sbjct: 33  RADGGPWGFQGCKQQLNVSVLGALPGAGWDNLRNLELGLVLGRAYSQCLTTEDGEYLIPD 92

Query: 83  EVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVK 142
            +  +P++E+ ++  +++++SW+NY    + S+N E +  S +NGKFS E Q ++   ++
Sbjct: 93  GMLAVPRRETVVQTRADLMDSWVNYTDAWAASVNAEFSFLSFLNGKFSAECQNVRRYSLQ 152

Query: 143 DQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYG 202
            Q +TTRVQ R+ IY+V+   T +    F + L+ + D LE NQT+ A YLAE+L+  YG
Sbjct: 153 YQTITTRVQRRHSIYSVRVRGTPDFHPDFRQRLLTLSDHLENNQTREAEYLAEMLVFAYG 212

Query: 203 THVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSL 262
           THV+T V+ GA LVQED V    + +    +  VT +A + F   V       +  ++ L
Sbjct: 213 THVLTEVEVGATLVQEDQVSRELVGNEDKDRLNVTFAASVLFDRKVGVGDAVSWDKESQL 272

Query: 263 TKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL 322
            + Y      S++ S GG PFY G+TL+ WQ+G+ N LVAI R+GLPL   ++P+ LP L
Sbjct: 273 VQAYQRGTVASKIHSRGGPPFYEGLTLQKWQEGVANRLVAIGRSGLPLPALLQPEALPEL 332

Query: 323 PGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSC-DAKVTNFTFGGV 381
           P P V+++   V  A+  YY  N HPGC    +PNF+  AN+DD SC D +  NF+FGGV
Sbjct: 333 PAPAVRRVEAAVSRAIGRYYEVNMHPGCVKRGAPNFDPLANVDDGSCTDGQHANFSFGGV 392

Query: 382 YQECTELS---GDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT- 437
           +QEC  ++   G  LC+     N LTG  SCP  Y+   L S+         +C  +C  
Sbjct: 393 FQECEAITGPEGGRLCKPYTILNPLTGQTSCPANYTASLLSSEVKVWSERSYQCWPQCQS 452

Query: 438 ---LKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVP-DNSGLLFGGVFTDKTINPMTNAQS 493
              +   C  +C ++         A WC  +G  P    GLLFGG+++    NP T AQ+
Sbjct: 453 CWLIFTCCHRMCGNLEIQRVVRVNASWCAPSGATPTAAPGLLFGGLYSPGRPNPRTGAQA 512

Query: 494 CPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLV------NSDTAKDVR 547
           CP+ + PL L   LKVCVS D+ELG   +VPFGGFFSC +GNPL        S+  K+V 
Sbjct: 513 CPSSFFPLTLLGDLKVCVSSDWELGVAHAVPFGGFFSCQVGNPLAAQARGQGSEFLKEVF 572

Query: 548 A-----PSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP--LMS 600
                      CP G+SQH A +S GCQ+ YC++AG       L +RLPP+   P  L +
Sbjct: 573 NLSVTMDHPMTCPAGYSQHPAYLSSGCQILYCLRAGFLLNPQQLMIRLPPFAARPSLLGN 632

Query: 601 QVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLG 660
                  ++ ++   R+W+K   +++W+  +  +   A  +     +  S G   G  LG
Sbjct: 633 SSGLGVSVLVDASGQRAWVKLQGSSRWRQADIHDPSVAAQLRDQGGSQPSAGAVVGACLG 692

Query: 661 VTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEED---PSPA 713
             + +  +     +G R+Y+K+ Y+ + E     G LA + TV    E    P+P+
Sbjct: 693 AVLGVVALALGVTWGFRRYQKRGYRRLPE-----GILAEEQTVYGTAETAESPAPS 743


>UniRef50_Q7SXE0 Macrophage expressed 1 n=10 Tax=Clupeocephala RepID=Q7SXE0_DANRE
          Length = 718

 Score =  812 bits (2096), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/697 (46%), Positives = 452/697 (64%), Gaps = 29/697 (4%)

Query: 30  GFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQ 89
           G ++C+    L  LEVLPGGGWDNLRN+DMGRVM+L+Y+ C+TTEDG Y+IPDEV+ IPQ
Sbjct: 29  GLRLCRKNSSLTALEVLPGGGWDNLRNIDMGRVMNLSYSQCQTTEDGVYLIPDEVFVIPQ 88

Query: 90  KESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTR 149
           K S +E NSE++ SW+  +S+TS S+N +++ FS +N KFSTE QRMKT QVK+ +VT R
Sbjct: 89  KVSGVETNSEIIMSWLEQKSSTSSSVNADVSFFSVLNAKFSTENQRMKTHQVKEGSVTAR 148

Query: 150 VQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSV 209
           VQVRN +YTVK  P   L   F K   +I D +E NQT+ A YL+E L+L+YGTHVITSV
Sbjct: 149 VQVRNHLYTVKAYPDFTLDSRFAKQAEEIADAIENNQTRHANYLSEKLVLDYGTHVITSV 208

Query: 210 DAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSN 269
           DAGA LVQED+++ S++ ++Q+ +++V+ASAG  F + V F +  +    +S +  Y  N
Sbjct: 209 DAGATLVQEDYLKMSYISNSQSDKSSVSASAGANFFDKVKFDIGGNTSQGSSQSSSYQGN 268

Query: 270 RTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKK 329
            T S +QS GG  FYPGITL+ WQ+   N+L AIDR+GLPLH+F+ P   P LP P V K
Sbjct: 269 ITYSLIQSHGGALFYPGITLQKWQQSTLNNLAAIDRSGLPLHYFLNPSTFPDLPTPTVNK 328

Query: 330 LSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELS 389
           L+ TV  A   YY  NT PGC NVDSPNFNFQAN+DD SC+  +TN +FGG+YQ+CT L+
Sbjct: 329 LASTVRKAAERYYKVNTIPGCVNVDSPNFNFQANVDDASCEGPITNLSFGGIYQKCTPLT 388

Query: 390 --GDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT------LKIF 441
             G+++C    QKN  TG +SCP  Y+   L S+  E+G++  EC   C       L   
Sbjct: 389 PDGNIICDETAQKNPATGGYSCPQHYNTTLLHSEVVEKGFNHYECHTHCHSCGFLGLSTC 448

Query: 442 CKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPL 501
           C   C D + V +A+    WC +  + P+NSG LFGG+F     NP+T + SCP  Y   
Sbjct: 449 CDKTCGDSYHVRRAKLETLWCSSTHKTPENSGYLFGGLFGPGIQNPLTKSSSCPPSYFTQ 508

Query: 502 NLFES-LKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQ 560
               + + +C+S DYE+G +FSVPF GFFSC  GNPL N  +          +CP  FSQ
Sbjct: 509 RFLSNGMMICMSNDYEIGTRFSVPFAGFFSCQSGNPLSNGQS----------RCPPQFSQ 558

Query: 561 HLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIK 620
           HLA ISDGCQV YCV++G+F+GG L PVRLPP+T+PP++  +ATNTV V  +E  RSW++
Sbjct: 559 HLAAISDGCQVLYCVQSGVFSGGHLKPVRLPPFTRPPVVGMIATNTVAVM-TEGERSWVR 617

Query: 621 DPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYK 680
             +T  W+L +P ++++  +++  D++ MSGG+ AG+ +G+ + + +V+   +   ++  
Sbjct: 618 VGETKMWRLAKPGDIKQMQSIL--DASEMSGGKKAGVAIGIIVLVALVVAGTVVIMKRRN 675

Query: 681 K-------KEYQEIEEQESLVGSLATDATVLNGEEDP 710
           +       + Y+EI E+ +               E+P
Sbjct: 676 RFSSLKLNRGYEEISEERNESSVEIEQEQNEAANENP 712


>UniRef50_Q6RYF9 Macrophage expressed protein n=5 Tax=Eumetazoa RepID=Q6RYF9_HALCO
          Length = 730

 Score =  747 bits (1928), Expect = 0.0,   Method: Composition-based stats.
 Identities = 260/732 (35%), Positives = 381/732 (52%), Gaps = 42/732 (5%)

Query: 5   MALVLIWMIIACAEADKPLGETGTTGF-----QIC-KNALKLPVLEVLPGGGWDNLRNVD 58
           +  VL+  I+A     + L       F     + C  +  KL   EVLPG GWDNLRNVD
Sbjct: 2   LGFVLVVSIVASVSGGELLDSVKKPEFPKGDVRACYGDNKKLERFEVLPGQGWDNLRNVD 61

Query: 59  MGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTE 118
            G V+   Y+ C+TTEDG+Y+IPD V TIP K S L + +E++  W +Y STT+  +N +
Sbjct: 62  AGLVVVYNYSRCRTTEDGRYLIPDTVNTIPLKASKLNVYAELISHWSSYTSTTAHGVNVD 121

Query: 119 LAL---FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKAL 175
             L     +V+GKFS+ ++ +K+ Q+ D++ TTRVQ+R   Y+ K  P + L   F   L
Sbjct: 122 AGLKYDSVQVSGKFSSGYESVKSKQIGDKSYTTRVQLRYVRYSAKLQPDASLHPTFKTRL 181

Query: 176 MDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT 235
           + I   L+ N+T  A Y +ELL+ ++GTHV+TSVDAGAALVQED V S F+   + ++N 
Sbjct: 182 LSIAGSLQLNKTDQARYDSELLVRDFGTHVVTSVDAGAALVQEDQVSSEFVNSRKFTKNQ 241

Query: 236 VTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFY-PGITLETWQK 294
           +TA A  +   I +  V     +   + K Y  +R++S++ + GG  F     T   W  
Sbjct: 242 ITAGASASLFGIFSIDVSYHSSTSNEVKKAYEQSRSSSQIDTLGGPMFKASNFTANDWTN 301

Query: 295 GITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVD 354
            + + LVA+DR+G PL F I    LP LP  ++ +L   VE  + HYY FNT+ GCT +D
Sbjct: 302 EVDHELVAVDRSGDPLFFLINSASLPELPNSVLYQLQNLVEETILHYYEFNTYRGCTELD 361

Query: 355 SPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSG---DVLCQNLEQKNLLTGDFSCPP 411
           SPNF+  AN+DD +C +  TN TFGGVYQ C+  SG     LC  L+Q N  TG  +CP 
Sbjct: 362 SPNFSPAANLDDGTCKSPYTNLTFGGVYQTCSMSSGSNNGDLCSGLDQVNPKTGGHTCPD 421

Query: 412 GYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDN 471
           GY  V L +    +  S   C   C L   C   C D +  ++A +  +WC A G V  +
Sbjct: 422 GYESVELHTGRLSDSKSVHSCH-SCWLFFKC---CHDNYYHSEATYIMHWCAATGPVSQD 477

Query: 472 SGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSC 531
           SG LFGG++T +  NP+T  ++CP  +    L + L +C+S DYELG K+S+PFGGF SC
Sbjct: 478 SGYLFGGLYTSQLNNPLTQGKTCPVNFYTRTLGKDLHICISDDYELGMKYSMPFGGFISC 537

Query: 532 IMGNPLVNSDTAKDV----------------RAPSLKKCPGGFSQHLAVISDGCQVSYCV 575
             GNPL  +   K                       K CP G+SQHLA +  GC+++YC+
Sbjct: 538 TTGNPLAMNPKPKSKGDMNSALPSLHSFFQGSKTWPKHCPKGYSQHLAYVDQGCEINYCL 597

Query: 576 KAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLEL 635
            AG  +   L  +R PP+   PL+     N V+        +W K+ +  Q+      E 
Sbjct: 598 LAGSLSEVGLPKIRRPPFQTAPLLLPSTENHVVF--DPVTLTWRKNQEAMQFISARVGEA 655

Query: 636 RRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVG 695
             + T     +   +G      TLG  +   +++ L     R+     Y+ +   + L+ 
Sbjct: 656 TPSSTGSGMSAGAAAGIAVV-ATLGCVVISTVIVVLIK--RRRKSSAGYRHLAIDDPLLS 712

Query: 696 SLATDATVLNGE 707
                 +     
Sbjct: 713 ----PQSNYGAT 720


>UniRef50_UPI0000F2D8B8 PREDICTED: similar to Macrophage expressed gene 1 n=1
           Tax=Monodelphis domestica RepID=UPI0000F2D8B8
          Length = 1065

 Score =  728 bits (1878), Expect = 0.0,   Method: Composition-based stats.
 Identities = 254/625 (40%), Positives = 363/625 (58%), Gaps = 28/625 (4%)

Query: 64  DLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFS 123
              Y+ C+ TED +Y+IPD+V+ +P++ES LE +SE++  W  Y    SL+IN E +  S
Sbjct: 150 GRNYSLCRVTEDREYLIPDQVHVVPRRESMLETHSEIIRDWRTYTDAFSLTINAEASFLS 209

Query: 124 RVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLE 183
            +NGKFS   QR K   V DQ +TTRVQ R  IY++   P   L+  F + L+ I + LE
Sbjct: 210 ILNGKFSASSQRSKVHSVYDQTITTRVQARQHIYSLAAQPPWVLAEAFRQQLLHISEHLE 269

Query: 184 KNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIA 243
            N+++ A+Y AELL+L YGTHV+T V+AGA+L+QED V+ + L +N   +  + ASA   
Sbjct: 270 NNRSQQASYQAELLVLAYGTHVLTEVEAGASLMQEDQVKRALLDENSTKKVGIAASASAI 329

Query: 244 FLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAI 303
           F + +          +     +Y+ N  +S++Q+ GG PFYPGITL+ WQ+ I N LVAI
Sbjct: 330 FFSRIQLGANLTGQVRNQQQWEYVKNTVSSKIQNHGGEPFYPGITLQKWQQSIPNRLVAI 389

Query: 304 DRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQAN 363
            R+GLPL FFI P+ LP L  P V++L+ TV+ A++ YY  NT+PGC    + NFNFQAN
Sbjct: 390 GRSGLPLPFFITPEALPELQVPSVRRLALTVQKAIQQYYAVNTYPGCLQPKASNFNFQAN 449

Query: 364 MDDDSCDAKVTNFTFGGVYQECTELSGD---VLCQNLEQKNLLTGDFSCPPGYSPVHLLS 420
           +DD SC+    +FTFGGV+Q+C  +SG     LCQ     N LTG  SCP  YS + L S
Sbjct: 450 VDDGSCEKAKHHFTFGGVFQKCQAVSGKGAETLCQPYRTANPLTGAASCPKNYSALLLNS 509

Query: 421 QTHEEGYSRLECKKKC----TLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQV-PDNSGLL 475
           +       ++EC+K+C     L   CKTVC +    +     AYWC  AG       G L
Sbjct: 510 ELRSSNVPQMECRKQCSSCYWLFQCCKTVCGNREHPSVVSLSAYWCSPAGSPALSKPGFL 569

Query: 476 FGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGN 535
           FGG++T+   NP+T AQ+CP  + PL LFE LKVCVS ++E+G   ++PFGGFFSC +GN
Sbjct: 570 FGGLYTNTQRNPLTKAQTCPHFFYPLVLFEDLKVCVSGNHEMGKSSAIPFGGFFSCRVGN 629

Query: 536 PLVN-----------SDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGS 584
           PL                 +D       KCP G+SQH A +S+GCQ+ YC++AG      
Sbjct: 630 PLAGFLQGQSPGMLKEVFYRDSPTVYPMKCPPGYSQHQAYLSEGCQILYCLQAGALFAQQ 689

Query: 585 LLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHG 644
           L+P+ LPP+ +PPL+++  T+   + +S+  +    D  T +   G   +          
Sbjct: 690 LVPIHLPPFIRPPLLNESYTDVDALVDSDANQISNLDDATKEALKGSGGD---------Q 740

Query: 645 DSNGMSGGEAAGITLGVTIALGIVI 669
           + +G      AG+ L + I+L IV 
Sbjct: 741 EHSGSGTWVTAGVWLPLVISLVIVA 765


>UniRef50_UPI0001796D85 PREDICTED: similar to Macrophage-expressed gene 1 protein precursor
           (Macrophage gene 1 protein) (Mpg-1) n=1 Tax=Equus
           caballus RepID=UPI0001796D85
          Length = 687

 Score =  723 bits (1866), Expect = 0.0,   Method: Composition-based stats.
 Identities = 265/707 (37%), Positives = 383/707 (54%), Gaps = 61/707 (8%)

Query: 23  LGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPD 82
           +G+ G  GFQ CK  L +PVL  LPGGGWDNLRNV++  V+   Y+ C TTE G+Y+I D
Sbjct: 19  MGDPGAPGFQGCKQTLNVPVLGALPGGGWDNLRNVELELVLRRYYSQCLTTEAGEYLIQD 78

Query: 83  EVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVK 142
           +++ +PQ+ES +E   E++                     + +NGK S + Q +K   ++
Sbjct: 79  QLHVVPQRESFVETRGELI---------------------NDLNGKSSIDCQNVKKYNLE 117

Query: 143 DQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYG 202
            Q VT RVQVR+ IY+VK     +    F + L+ + D LE +Q + A YLAE+L+L YG
Sbjct: 118 YQMVTARVQVRHSIYSVKAPEIPDFQPTFRQHLLALSDHLENDQIREAEYLAEMLVLWYG 177

Query: 203 THVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSL 262
           THV+T V+AGA LVQED VR   +      +N VT++A   F ++VNF     + +Q+ L
Sbjct: 178 THVLTDVEAGATLVQEDQVRRELVDSQAGERNNVTSTASAVFFHMVNFGDAASWQAQSQL 237

Query: 263 TKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL 322
            +DY+ N   S+++S GGVPFYPGITL+ WQ+GI+N LVAI R+ LPL   ++P+ LP L
Sbjct: 238 FQDYVRNTVASKMRSQGGVPFYPGITLQKWQEGISNRLVAIGRSELPLPALLQPEALPEL 297

Query: 323 PGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVY 382
           P P V++++  V  A+  YY  N  PGC    +P FN QAN++D SC    +NF+FGGV+
Sbjct: 298 PAPTVQRVAAAVRRAIHRYYAVNALPGCLRRGAPAFNPQANLEDGSCGGGRSNFSFGGVF 357

Query: 383 QECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT----L 438
           QEC  +SG                   P  Y+   L S+       R EC+++C      
Sbjct: 358 QECEAVSGQT-----------------PTSYTASALHSELKTWSEPRPECQQQCRKCWLF 400

Query: 439 KIFCKTVCEDVFRVAKAEFRAYWCVA-AGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAG 497
              C+TVC    + +     A WCV     +P  SG LFGG+++    NP T AQ+CP+ 
Sbjct: 401 FQCCQTVCATHEQRSVVRLAASWCVPSQASLPATSGFLFGGLYSPGNSNPFTKAQACPSY 460

Query: 498 YIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVN-----------SDTAKDV 546
           +  L LF  LKVCVS D ELG   +VPFGGFFSC +GNPLV                +D 
Sbjct: 461 FYALTLFGDLKVCVSSDLELGAAQAVPFGGFFSCQVGNPLVGLLKGQSPGLLQEMFCQDS 520

Query: 547 RAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLM--SQVAT 604
                 KCP G+SQH A +S+GCQ+  C++AG   G     VR+PP+   P +  S  A 
Sbjct: 521 PTDHPMKCPAGYSQHQAYLSNGCQIFCCLRAGALLGQQQAAVRMPPFLPRPPLLNSSSAH 580

Query: 605 NTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIA 664
           +  ++ +S   R W++   ++ W+     +L  A  ++    +  S G  AG  +G  +A
Sbjct: 581 SLSVLVDSTGQRVWVRLQGSDCWQQANINDLSLAAKLLSQAGSKPSIGAIAGSWVGTLVA 640

Query: 665 LGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPS 711
           + +V     YG R+YKK  Y+ ++      G L  +       E  +
Sbjct: 641 VVVVTLGISYGFRRYKKGGYKRLQ-----GGILTEEQGGYGTTETTA 682


>UniRef50_B3F732 Macrophage expressed protein 1-like protein n=1 Tax=Crassostrea
           gigas RepID=B3F732_CRAGI
          Length = 621

 Score =  698 bits (1801), Expect = 0.0,   Method: Composition-based stats.
 Identities = 239/622 (38%), Positives = 340/622 (54%), Gaps = 35/622 (5%)

Query: 39  KLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNS 98
            +   EVLPG GWDNL+N D G ++   Y+ C+TT+DGQY+IPD VYT+P K S LE+  
Sbjct: 4   NVARFEVLPGLGWDNLQNKDAGMLVQYNYSECRTTDDGQYLIPDGVYTVPLKSSKLEVFG 63

Query: 99  EVLESWMNYQSTTSLSINTELALF---SRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNR 155
           E+ + W N+ STTS S+N E  L      ++GK+S E   ++  Q+ D++VTTRVQ R  
Sbjct: 64  ELFQHWNNFTSTTSSSVNVEAGLHLGSFGISGKYSHESDSVRKHQIMDRSVTTRVQARYA 123

Query: 156 IYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAAL 215
            Y+    P + L+  F   L +I   ++ N+T MA Y ++LL+ +YGTHVI+SV    + 
Sbjct: 124 RYSALLQPDTPLNPAFRDRLRNIAYYIQTNKTNMARYQSQLLVRDYGTHVISSVQRVPSS 183

Query: 216 VQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRV 275
           +    +R   +      +  V           V    E  + + T +   YL NRT+S +
Sbjct: 184 LSLTRLRRRSVTVTAWDRRQVVGRGQCLVYERVYVGAEYKHSTSTEVIDQYLGNRTHSVI 243

Query: 276 QSFGGVPFYP-GITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTV 334
            + GG  F P   TL  W  G++  LVA+D++G P++  I    LP LP  ++  L +TV
Sbjct: 244 NAIGGPVFQPNNFTLNQWASGLSGDLVAVDKSGYPIYELISAQTLPELPPSILFPLVQTV 303

Query: 335 ETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELS--GDV 392
           ++AV  YY FN + GCTN+DSPNF+F AN+DD +C++  TN+TFGGVYQ+C +       
Sbjct: 304 KSAVEEYYKFNIYRGCTNLDSPNFSFIANVDDGTCESPETNYTFGGVYQQCKQSGQLSQN 363

Query: 393 LCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRV 452
           LC  L QKN LTG  SCP GY  V L   T     SR  C     L +  +  C++    
Sbjct: 364 LCNGLVQKNPLTGAQSCPSGYESVLLNEGTRSATESRRRCHHCGFLGL--RHCCDNYNVY 421

Query: 453 AKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVS 512
             A+++++WCVA G V   SG  FGG++T+K  NP+T ++ CP  + PL L   ++VCVS
Sbjct: 422 GSAKYQSFWCVAQGHVDQQSGFQFGGIYTNKIDNPLTQSRGCPLYFYPLKLGLGMQVCVS 481

Query: 513 LDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVR--------------APSLKKCPGGF 558
            DYELGF++SVPF G FSC+ GNPL                            + CP G+
Sbjct: 482 DDYELGFRYSVPFAGLFSCMTGNPLAVHQDTSFKNPDMLHSLSSYLKASNNWPRGCPTGY 541

Query: 559 SQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP----LMSQVATNTVIVTNSET 614
           S HLA I + C+++YCVKA  F+   L PVR PP+   P    + S ++   +I T  ET
Sbjct: 542 SMHLATIENSCEINYCVKANAFSDKGLPPVRRPPFMDLPGDAYVDSGISEEYMISTGGET 601

Query: 615 ARSWIKDPQTNQWKLGEPLELR 636
              W          LG P + R
Sbjct: 602 ---WTDL------TLGGPAQFR 614


>UniRef50_A7SEK6 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
           RepID=A7SEK6_NEMVE
          Length = 583

 Score =  676 bits (1744), Expect = 0.0,   Method: Composition-based stats.
 Identities = 241/593 (40%), Positives = 335/593 (56%), Gaps = 19/593 (3%)

Query: 44  EVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLES 103
           EVLPGGGWDNLRN+ MG V  + Y+ C++++DG++++PD V+  P K+S +   +E  + 
Sbjct: 1   EVLPGGGWDNLRNLHMGAVSAMNYSLCRSSDDGKFLVPDNVFLYPVKKSKVNTFAEFYDH 60

Query: 104 WMNYQSTTSLSINTELA---LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVK 160
           W NY STT+ SIN E      F  V+G FS+E++ +K  QV+D+ VTTRVQ+R+  YT K
Sbjct: 61  WNNYSSTTTKSINAEAKASFGFGSVSGSFSSEYESVKKHQVEDKTVTTRVQLRHVFYTAK 120

Query: 161 TTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDH 220
             P S L   F   L++I   L+ N T  A++LA++L+ ++GTH ++SVDAGA L + DH
Sbjct: 121 LQPDSPLQPAFKDRLLEIASHLQHNNTAYASFLAQVLVRDFGTHYVSSVDAGAVLAKVDH 180

Query: 221 VRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG 280
           +   F+ D+   ++ +TASA  +F +           + T    +Y      S   ++GG
Sbjct: 181 LTKKFVADSNEDKSKITASASASFFHFFGASGSYSKSTDTKTLDEYTKATVYSTTYTYGG 240

Query: 281 VPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRH 340
            PF    T+  W+  + + LVA+DR+G PLH+ I P  LP L      +L+  V+ A++ 
Sbjct: 241 PPFRVNFTINEWEDKMLDELVAVDRSGDPLHYTITPGSLPELCEQATFQLAAVVKNAIKQ 300

Query: 341 YYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELS--GDVLCQNLE 398
           YY  NT  GCT +DSPNF+FQANMDD SC +   N+TFGGVYQ C          C  L 
Sbjct: 301 YYIHNTIKGCTKMDSPNFSFQANMDDGSCQSPTNNYTFGGVYQTCQTDGSPSSDPCAPLA 360

Query: 399 QKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFR 458
           QKN LT D++C PGY PV +      +G +   C K C         C    +     F 
Sbjct: 361 QKNPLTADYTCTPGYEPVLVH-----QGRTPQSCHKDCHRVWLFFKRCS--VQCGFGSFS 413

Query: 459 AYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELG 518
            YWCVA   VP NSG LFGG+++D   NP+T   SCP  +  L    ++KVCVS DYELG
Sbjct: 414 TYWCVAKSAVPANSGYLFGGLYSDVLKNPLTQDHSCPLKFYALKFGATMKVCVSDDYELG 473

Query: 519 FKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAG 578
           ++ S+PFGGFFSC  GNPL              K CP GFSQHL  I   C++ YCVK+ 
Sbjct: 474 YQQSLPFGGFFSCNAGNPLAFKKPPTGD-----KGCPTGFSQHLGAIEANCEIQYCVKSN 528

Query: 579 IFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQ-TNQWKLG 630
           +F    L  VR PPY  PP +   +   +++ N +T + W K      QW L 
Sbjct: 529 VFNLQGLPIVRRPPYLSPPAVYNYSVP-MLLVNEDTGQIWFKRAGNMPQWLLA 580


>UniRef50_Q4W1E5 Macrophage expressed protein n=1 Tax=Suberites domuncula
           RepID=Q4W1E5_SUBDO
          Length = 676

 Score =  599 bits (1545), Expect = e-169,   Method: Composition-based stats.
 Identities = 211/600 (35%), Positives = 319/600 (53%), Gaps = 68/600 (11%)

Query: 22  PLGETGTTGFQIC-KNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYII 80
           P G+      + C     KL +L+V+PG GWDNLRN + G +   +Y+ CK T D +Y+I
Sbjct: 57  PRGDP-----RNCLSGNPKLNILQVVPGIGWDNLRNSETGILTSFSYSQCKVTYDRRYLI 111

Query: 81  PDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQ 140
           PDE + IP K S ++  +E+ + W  Y+S TS SIN     F ++ G             
Sbjct: 112 PDETFAIPIKTSTIDYQAELFDHWDAYKSVTSRSINAGFDFFGKIGG------------- 158

Query: 141 VKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILN 200
                                               +I   L+ N T+ A Y A++LI +
Sbjct: 159 ------------------------------------EILSLLKSNDTESADYAAQILIRD 182

Query: 201 YGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQT 260
           YGTH ITS+DAGA L++ED+++S+ + + +   ++++ +AG+ F +++  +    + S +
Sbjct: 183 YGTHCITSIDAGAVLIKEDNLKSTIMSNYKGRADSLSTAAGVEFYDMLKLRASAGFSSYS 242

Query: 261 --SLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDK 318
             S  K Y  NRT+SR+ ++GG P+  G+ L  W+  + N+LVA DR+G P H       
Sbjct: 243 GDSDLKAYRQNRTSSRLYTYGGPPYKLGMNLSRWENDLMNNLVATDRSGKPSHSLSTTQS 302

Query: 319 LPGL--PGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDD-DSCDAKVTN 375
           L         V  L + V++AV  YY +NTH GC N  +PN + Q N      C     N
Sbjct: 303 LKPEVTTSQEVFLLRRLVKSAVSQYYHYNTHTGCKNPKAPNLDHQTNNGAPGVCKEPSAN 362

Query: 376 FTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLEC--K 433
           +TFGGV+Q C   +G+ +C  L QKN LTG +SCP  +  + L   T      R  C  K
Sbjct: 363 YTFGGVFQSCRS-NGNDICGKLLQKNPLTGGYSCPKNFKALLLQLGTERSHKMRRVCVWK 421

Query: 434 KKCTLKIF-CKTV--CEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTN 490
           +KCT  +F C  V  C  V  V  A ++ YWC    + P   G +FGG++++   NP+T 
Sbjct: 422 RKCTFFVFNCHDVDDCTFVPSVEIASYQTYWCAPNKKNPPKFGYMFGGIYSNDIQNPITR 481

Query: 491 AQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAP- 549
           + SCP  ++PL + E   VCVS DYELG +FS+PFGGFFSC+ GN L  + +++ +  P 
Sbjct: 482 SCSCPTHFLPLRMGERATVCVSEDYELGHQFSLPFGGFFSCVSGNVLAGNGSSEFLNNPK 541

Query: 550 -SLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVI 608
               +CPGGF+QHLA+   GC+V++CVKAG     S L + LPP+   P + + +T+ + 
Sbjct: 542 DWPMRCPGGFTQHLALTEKGCRVNFCVKAGSLLRASDLELVLPPFDPKPTLRKNSTSDLF 601


>UniRef50_C4Q3P0 Expressed protein n=2 Tax=Schistosoma RepID=C4Q3P0_SCHMA
          Length = 1103

 Score =  528 bits (1359), Expect = e-148,   Method: Composition-based stats.
 Identities = 196/605 (32%), Positives = 296/605 (48%), Gaps = 70/605 (11%)

Query: 2   NSFMALVL---IWMIIACAEADKPLGETGTTGF-QICKNALKLPVLEVLPGGGWDNLRNV 57
           N+   L++      +I  + ++ P  +T +    + C        L VLPG GWDNL N 
Sbjct: 294 NNHHVLIITNIYSSVIEKSSSENPSDQTISYSLPKECTLFPNQKYLSVLPGFGWDNLVNR 353

Query: 58  DMGRVMDLT-YTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSIN 116
           + G ++D+  Y+ C+ + DG+++IPDE+   P K S ++++SEV ES    +S  + SIN
Sbjct: 354 ERGPIIDVEKYSLCRRSVDGKFLIPDEITVQPIKNSEIKLSSEVYESISQCRSLVAYSIN 413

Query: 117 T----ELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRV-----------QVRNRIYTVKT 161
           +    E + F R+NG FS++ + ++   VK   VT               +RN +  V  
Sbjct: 414 SAVGGEYSYF-RINGDFSSDKETLREKLVKHGNVTMETIELFNNGLIGNTLRNSLGIVTN 472

Query: 162 TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHV 221
                LS G                   A YLA+L++ ++GTH I SV AG  L + D +
Sbjct: 473 DNFKSLSQGM-----------------NAFYLADLVVRDFGTHCINSVYAGGVLAKIDTL 515

Query: 222 RSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGV 281
            ++ L   +  +  + ASA I+F N+ N K+        SL ++Y S  T S++ ++GG 
Sbjct: 516 DTNSLNTKKEDRWHLGASATISFANLFNVKLGGSANVNDSLIQNYESKITYSQILTYGGP 575

Query: 282 P-FYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRH 340
             +   + L  W+ G+ N LVAIDR+G P++  I    LP L   ++ +L  T+++AV  
Sbjct: 576 IIYMSNVNLSLWESGLDNQLVAIDRSGQPIYELITDRSLPELSSHMIVRLVATIKSAVER 635

Query: 341 YYTFNTHPGCTNVDSPNFNFQANMDDDSCD---AKVTNFTF--GGVYQECTELSGDVLCQ 395
           YY  NT  GC N  S  ++ +AN+    CD    ++TN T   GGVYQ+CT    D LC 
Sbjct: 636 YYKANTVVGCMNPLSVFYDNEANVASPECDLQSKQITNTTLYLGGVYQKCT--GPDDLCL 693

Query: 396 NLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLK-IFCKTVCEDVFRVAK 454
                N LTGD  C  GY  + LL Q   + YS   C +K   K   C T C        
Sbjct: 694 GETIPNPLTGDLFCSQGYVSIQLLPQQVRKCYSV--CDEKSWFKNPECTTQC-------- 743

Query: 455 AEFRAYWCVAAGQVPD---------NSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFE 505
           A   +YWC     +           +SG LFGG++TDK +N +T   +CP  Y P+ L  
Sbjct: 744 AITESYWCSRDPSLSSSSSNILDNSDSGYLFGGLYTDKEVNSLTKQYNCPQYYWPITLGR 803

Query: 506 SLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVN----SDTAKDVRAPSLKKCPGGFSQH 561
            +++C+S D ELG K+S+PFGGF+SC  GNPL      + T K        + P  F   
Sbjct: 804 RMRICLSTDRELGGKYSLPFGGFYSCYSGNPLTALININQTDKIDSNEQHTRIPEWFKIQ 863

Query: 562 LAVIS 566
              +S
Sbjct: 864 QERMS 868



 Score =  119 bits (297), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 22/132 (16%)

Query: 538  VNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPP 597
            V +D ++   A   KKCP G++ HLA + D CQV+YCV+A          ++ PP+  P 
Sbjct: 919  VQNDFSQLFAALWPKKCPVGYTAHLAAMEDICQVNYCVQANFLKEQVRRQLKRPPFVLP- 977

Query: 598  LMSQVATNTVIVTNSETARSWIKDPQ-----------TNQWKLGEPLELRRAMTVIHGDS 646
                      I TN E   S+  DP            ++ +KL +      + +    D 
Sbjct: 978  ----------IYTNEEKLPSFSNDPHGRSILTELSFDSHLFKLSDSNNFIESSSNELHDK 1027

Query: 647  NGMSGGEAAGIT 658
            NG    +  G  
Sbjct: 1028 NGNIIRKINGRW 1039


>UniRef50_Q2XSC0 Macrophage expressed protein (Fragment) n=1 Tax=Mytilus edulis
           RepID=Q2XSC0_MYTED
          Length = 338

 Score =  385 bits (989), Expect = e-105,   Method: Composition-based stats.
 Identities = 126/343 (36%), Positives = 185/343 (53%), Gaps = 13/343 (3%)

Query: 210 DAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSN 269
           D+GA++V+ DHV+   L D+   +  ++A+AG        F V+        +   YL++
Sbjct: 3   DSGASIVKVDHVKRELLQDDTIDKFQISAAAGAEL-----FGVQVGITIPAEVMTKYLAS 57

Query: 270 RTNSRVQSFGGVPFYP-GITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK 328
           +T+S + + GG  + P   T+  W K I  +LV++DR+G PLHF I     P L   +V 
Sbjct: 58  KTHSSILTHGGPLYLPVNFTINDWVKQIDQNLVSVDRSGDPLHFIINEYMFPELSISIVT 117

Query: 329 KLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAK--VTNFTFGGVYQECT 386
             +  VE+A++ YY  NTH GCTN DSPN+N+ AN+DD +C+     TN  FGGV+Q C 
Sbjct: 118 DTAAAVESAIKTYYKMNTHRGCTNRDSPNYNYLANVDDGTCEYNLNATNTNFGGVFQTCN 177

Query: 387 ELSGDV-LCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTV 445
                  +C     KN LTGDFSCP G+  V L         ++ E  + C+  +   + 
Sbjct: 178 VTGNIDGICDTFLSKNPLTGDFSCPNGFIAVPLFLG----HDNKEEVHRTCSKYMIFWSH 233

Query: 446 CEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFE 505
           CE    +  A +++YWC   G      G LFGG++T +  N +T  QSCP  +  + + E
Sbjct: 234 CETTSNLGTASYQSYWCCPQGGNQSFPGYLFGGLYTTQLPNVVTQHQSCPQYFTAIGIAE 293

Query: 506 SLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRA 548
            LK+CVS D E GF++S+PFGGFFSC   N L  +  A    A
Sbjct: 294 DLKICVSDDIENGFQYSIPFGGFFSCQNDNLLAANQNATHCHA 336


>UniRef50_Q80VB7 Mpeg1 protein (Fragment) n=1 Tax=Mus musculus RepID=Q80VB7_MOUSE
          Length = 232

 Score =  359 bits (920), Expect = 3e-97,   Method: Composition-based stats.
 Identities = 231/232 (99%), Positives = 232/232 (100%)

Query: 482 DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD 541
           DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD
Sbjct: 1   DKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSD 60

Query: 542 TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ 601
           TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ
Sbjct: 61  TAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQ 120

Query: 602 VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV 661
           VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV
Sbjct: 121 VATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGV 180

Query: 662 TIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 713
           TIALG+VITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA
Sbjct: 181 TIALGVVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA 232


>UniRef50_Q8I2S3 MAC/Perforin, putative n=9 Tax=Plasmodium RepID=Q8I2S3_PLAF7
          Length = 821

 Score =  268 bits (685), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 94/504 (18%), Positives = 163/504 (32%), Gaps = 85/504 (16%)

Query: 20  DKPLGET---GTTGFQICKNALKLPVL-EVLPGGGWDNLRNVDMGRVMDLTYTNCKTTED 75
             P+G+       G++     L  P   E  P    DN  N++          +C  +E 
Sbjct: 251 GNPIGDPFLKVDPGYRDSIIKLTYPKSDEDYP----DNYMNINPNGSFVRNEISCNRSE- 305

Query: 76  GQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQR 135
                         KES +   SE  +       +   SI     LF   +     +   
Sbjct: 306 --------------KESEISTMSEYTKEL-----SVDASIGASYGLFGSFSASTGYKSVS 346

Query: 136 MKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAE 195
               + K +    +      + ++      +L+  F +A+  +      +  K  TY ++
Sbjct: 347 NTISKNKFRMFMLKSYCFKYVASLSQYSQWKLTDQFVRAISLLPSHF-NSLEKDGTYCSD 405

Query: 196 L--------------------LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT 235
                                   N+GTHV T +  G  + Q+  +  +       S  +
Sbjct: 406 EEFRDNRKSEKCGKSVTAWMYFFKNFGTHVSTLLHLGGKITQQVKISKNDYKAMTESGLS 465

Query: 236 VTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG-VPFYPGI--TLETW 292
           ++AS    F  +   K  T+  S  S   +  ++         GG   F P      E W
Sbjct: 466 ISASVSAGF-GLFKVKGSTNTESNESSNNESSTSSLEKETVIIGGTTIFDPNDPNNFEKW 524

Query: 293 QKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTN 352
            + I+ + + I     PL        LP        +LSK  E A+R Y + N  P    
Sbjct: 525 AESISENPMPIKGEYEPL-----SRILP-------TRLSKIYEEALRFYISVN-VPSNFG 571

Query: 353 VDSPNFNFQANMDDDSCDAKVTNFTFGG-VYQECTELSGDVLCQNLEQKNLLTGDFSCPP 411
             + N   Q N+ ++   A + + +  G V  EC E    +L  +L   N L        
Sbjct: 572 QITDNEIRQYNIKEELMKATMIHSSGTGLVVVECEEKQNFLLGFSLSIPNDL-------S 624

Query: 412 GYSPVHLLS--QTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAE---FRAYWCVAAG 466
                +L S  +  ++ YS++       +   CK      F              C    
Sbjct: 625 NLKDFYLNSCDEDSDKCYSKMSDNAYSYIFAMCKEEMIPFFEQKVKSGVGLLTLECSEKN 684

Query: 467 QVPDNSGLLFG-GVFTDKTINPMT 489
           QV     +LFG G+    T +P++
Sbjct: 685 QV-----ILFGFGISVLNTNDPIS 703


>UniRef50_UPI00006A1994 UPI00006A1994 related cluster n=5 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI00006A1994
          Length = 520

 Score =  207 bits (527), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 65/392 (16%), Positives = 130/392 (33%), Gaps = 54/392 (13%)

Query: 25  ETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVM---------DLTYTNCKTTED 75
           + G+   + CK A  +P   +L G G D +     G  +         + T T C+   +
Sbjct: 5   KPGSP--EECKKASFVPGHTLL-GQGLDIVTMKKTGAFLLDMQIYQIPNKTCTLCENPYN 61

Query: 76  GQYIIPDEVYTI---PQKESNLEMNSEVLESWMNYQSTTSLSINTELAL----------- 121
            + +    +  +   PQ      ++S ++ S ++  +  + ++  +  +           
Sbjct: 62  KKILEKLPISMVDWTPQTSCIRNIDSSLMRSKVSLANKEASNVQNDWKVGLDIPVKTVTV 121

Query: 122 FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQ 181
            + + G  S   +  ++  + DQ      ++    Y+ + +P + LS  F K L  + + 
Sbjct: 122 HTALAGSHSKLAEFAQSKTITDQYSFLSHELSCAFYSFRLSPDAPLSSYFAKDLRQLPNL 181

Query: 182 LEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAG 241
             KN  +         I  YGTH +T    G  + +   VR+  +  N    + V     
Sbjct: 182 YNKNTKQK----YRSFISTYGTHYVTEAHVGGRIKEITAVRTCQVAMNSLKMSEVKDCLE 237

Query: 242 IAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQ---KGITN 298
           +     VN +          L+  +   + N+  Q   G  F+      T++      T 
Sbjct: 238 LEIAGSVNIEAA---DIGRGLSNKFCKEKANNINQ---GSDFHTSFNERTYEVKGGKATF 291

Query: 299 HLVAIDRAGLPLHFFIKPDKL---PGLPGPLVKKL----------SKTVETAVRHYYTFN 345
           +L      G P  F    + L   P L    +  +             V+ AV  Y    
Sbjct: 292 NLFDEKSGGKPEEFSAWMESLKTIPDLVAFSLSPIHNLVRLNGPQKNNVKKAVSDYINEK 351

Query: 346 THPGCTNVDSPNFNFQANMDDDSCDAKVTNFT 377
                        +  +   D SC    T ++
Sbjct: 352 ALR--MKCSCSGNSHPSRNGDCSCVCPATKYS 381


>UniRef50_Q23QV5 MAC/Perforin domain containing protein n=1 Tax=Tetrahymena
           thermophila SB210 RepID=Q23QV5_TETTH
          Length = 518

 Score =  205 bits (521), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 66/390 (16%), Positives = 135/390 (34%), Gaps = 35/390 (8%)

Query: 6   ALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLP--GGGWDNLR-------N 56
             ++  ++I   +A    G+  T  +    +   +  +  +   G G++           
Sbjct: 8   VFLVFILLIGQCQAGYLRGQDQTILWNNTIDPASIGYIPNVQYLGSGYNIYFANPHSTTG 67

Query: 57  VDMG----RVMDLTYTNCKTTE---DGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQS 109
           +D G     +++L Y N   T    D  Y +PD V    +K   +   S+ + S   Y+ 
Sbjct: 68  LDPGFTNSGILELDYNNNLWTNINPDRSYYVPDNVSLTVEKSCIVSFQSQEVNSLSQYRD 127

Query: 110 TTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSL 169
           + S S+  +   F+      S+++Q ++             Q R  I+ +    +   + 
Sbjct: 128 SLSSSVQFQAKYFAG-KFSASSDYQEVQDGLNSANIQYIESQARCSIFQLDVYNSPSQNA 186

Query: 170 GFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDN 229
             T  L      L  NQT    Y     I  +GTHV+TSV+ G+    +  +       N
Sbjct: 187 QLTPQLQQALFTLAFNQTSQNDYYD--FIDTWGTHVVTSVNLGSRFGYKYQMDK--YQSN 242

Query: 230 QNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITL 289
           Q +Q  V  S   ++ +           +     +++    T+    S G  P       
Sbjct: 243 QLTQQGVNLSVSASYFSSSGSASGAYNQT---QIQNFTQAMTSWSSYSIGATP-DANQDP 298

Query: 290 ETWQKGITNHLVAIDRAGLPLHFFIKPDKLP--GLPGPLVKKLSKTVETAVRHYYTFNTH 347
            +W +   +  + I+ + L    F+        GL    +  +   +   ++ Y      
Sbjct: 299 LSWAQQTLDTPMPINISILSFDDFLNKFSFSVNGLTSSQLNTVISNLSQYLQTY------ 352

Query: 348 PGCTNVDSPNFNFQANMDDDSCDAKVTNFT 377
             C N    N    A  D +   +++  ++
Sbjct: 353 --CANRLLVNGKIDACADQEVSSSQIFQYS 380


>UniRef50_Q23QV7 E1-E2 ATPase family protein n=4 Tax=Tetrahymena thermophila
           RepID=Q23QV7_TETTH
          Length = 1982

 Score =  203 bits (517), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 72/385 (18%), Positives = 131/385 (34%), Gaps = 49/385 (12%)

Query: 20  DKPLGETG-TTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQY 78
             PL  +G   GF+       LP +++L     DNL +                + D  Y
Sbjct: 57  GNPLSNSGIDPGFR------NLPTVDLLYQ---DNLWDS--------------VSPDRAY 93

Query: 79  IIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKT 138
            IPD V    +K   +  +S+ + +  +YQ++ S  +N + +LF+  +   S +FQ+M+ 
Sbjct: 94  FIPDGVRLTIEKSCLITFSSKDVSTLNDYQNSLSAQVNGKGSLFA-ASFSASADFQQMQD 152

Query: 139 LQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQL--EKNQTKMATYLAEL 196
              +              + +            +  L+D   QL    N T    Y  + 
Sbjct: 153 TLSQKDNQCIHSFATCSAFDLSFYNDPNSIPLLSLQLVDKIQQLYSYSNYTNEREYYYD- 211

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
              ++GTHV TS+  G+          S     Q S     AS G +       + +   
Sbjct: 212 FFDSWGTHVATSIKLGSLFGY--QFIMSSSSVQQQSNLGFDASVGASLYG---VQGKVST 266

Query: 257 ISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKP 316
                    + S+  +    S G  P    +    W     +  + I     P++ FI  
Sbjct: 267 DYSQQQLNSFQSSLKSWSSYSMGATP-NANLDASEWATQTLDTPMPIKTDLTPIYEFISQ 325

Query: 317 -DKLPGLP--GPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKV 373
               P +P     +  +   ++  +  Y        C +       FQ+N+D+ S     
Sbjct: 326 YQNNPAIPIDSATLTYVVNAMQNYIIQY--------CYDR----LQFQSNLDNCSGYVNS 373

Query: 374 TNFTFGGVYQECTELSGDVLCQNLE 398
           ++  + G  Q     S   +  NL 
Sbjct: 374 SSDPYVGSRQIMNTKSAKFVSYNLT 398


>UniRef50_A0T3F5 Apextrin n=1 Tax=Acropora millepora RepID=A0T3F5_ACRMI
          Length = 854

 Score =  190 bits (482), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 49/312 (15%), Positives = 101/312 (32%), Gaps = 19/312 (6%)

Query: 52  DNLRNVDMG----RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNY 107
           D     D G          Y +  TT DG++ +PD ++ +      +E NSE   S  +Y
Sbjct: 246 DPSTGTDPGIRIYPTFVTNYDSGMTTSDGKWAVPDGLFFLITVSCVIEFNSEESRSSSSY 305

Query: 108 QSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSEL 167
            ++ +  + T+   F     K + +         +      + Q     Y        +L
Sbjct: 306 MNSLTNEVGTDSKFFGAY-FKANVKVSSKNEELHEASYSYVKSQAVCSYYKGSI--FPDL 362

Query: 168 SLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLL 227
               T  ++    +   N T         L+  +GTH I     G+    E  + +    
Sbjct: 363 PPRLTPQILATMKKCSDNPTDDNF---NNLVEYFGTHYIAQGVMGSKFGSESKLSTEKYE 419

Query: 228 DNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGI 287
           + Q++   V  +AG  +  + +   + +  SQ    + + + R +    ++G      G 
Sbjct: 420 ELQSNGINVGTAAG--YEGMFSAGYQQETDSQREQREAFENARESKFSYTYGTQMPADG- 476

Query: 288 TLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK------KLSKTVETAVRHY 341
           +  TW    +   + I+     +   +       L    +       KL + +    +  
Sbjct: 477 SANTWASQTSQTPMPINIELTSISELLTDTFKTDLDEKQIDYETLRPKLVEYLTRYCQQL 536

Query: 342 YTFNTHPGCTNV 353
              N    C   
Sbjct: 537 VDENKAKDCMPP 548


>UniRef50_B3L016 Sporozoite protein with MAC/Perforin domain n=1 Tax=Plasmodium
           knowlesi strain H RepID=B3L016_PLAKH
          Length = 844

 Score =  189 bits (480), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 54/349 (15%), Positives = 109/349 (31%), Gaps = 56/349 (16%)

Query: 43  LEVLPG-----GGWDNLRNVDMG--------------RVMDLTYTNCKTTEDGQYIIPDE 83
           L V PG      G+D+L    +G               +M+  ++N     D   + P  
Sbjct: 241 LSVFPGMYFAGIGYDSLFGNPLGESDSLTDPGYRGQIILMNWEFSNKGVANDLATLQPLN 300

Query: 84  VYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKD 143
            +   +   +   + +   S  +Y    +   +   +         ST +++      K 
Sbjct: 301 GWIRKENACSRAESIKECSSISDYTKNLTAEASVSGSYMGFGAFSASTGYKKFLQETSKR 360

Query: 144 QAVTTRVQVRNRIYTVKTTPT--SELSLGFTKALMDICDQL-----------------EK 184
              T  ++     YTV   P    E +  F  A+  +                     + 
Sbjct: 361 TTKTYLIKSNCVKYTVGLPPYVHWEQTTAFKNAVDGLPPHFIGLEAESECASDVYEQKKT 420

Query: 185 NQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF 244
           ++   + +        YGTH+I     G  + +   V ++ +   +    +V A     F
Sbjct: 421 SEECESVHAWITFFKTYGTHIIMEAQLGGKITKVVRVENTSVNQMKKDGISVKAQVKAQF 480

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYP---GITLETWQKGITNHLV 301
               +    T+  S  S   +  +   + ++   GG P         L  W K ++ + +
Sbjct: 481 -GFASVGGSTNVSSDNSSKTNENNYEMSEQLVVIGGNPIKDVTKEENLYEWSKTVSTNPM 539

Query: 302 AIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY---YTFNTH 347
            I+   LP+                   L  + E A+ +Y   Y F+ H
Sbjct: 540 PINIRLLPIS-----------TIFESDDLKSSYEKALIYYTRLYGFSPH 577


>UniRef50_Q23QV6 MAC/Perforin domain containing protein n=2 Tax=Tetrahymena
           thermophila SB210 RepID=Q23QV6_TETTH
          Length = 538

 Score =  186 bits (473), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 59/350 (16%), Positives = 117/350 (33%), Gaps = 34/350 (9%)

Query: 40  LPVLEVLP--GGGWD-NLRNVDMGRVMDLTYTNC---KTTEDGQYIIPDEVYTIPQKESN 93
             +    P    G D   +N+     ++LTYT+        +  Y +P+ V+   QK   
Sbjct: 54  YNIFTSNPHSSQGLDPGYKNI---AAINLTYTDNLWQNVNPERTYFVPNGVFLSQQKSCT 110

Query: 94  LEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVR 153
           +   +  + S M+Y S+   S++ +   F     + S ++Q M+      +         
Sbjct: 111 MSFTARQVASMMDYTSSLEASVSIKGTFFGG-RFRASVDYQDMQNDMESGEYQYIVSHSS 169

Query: 154 NRIYTVKTTPTSELSLGFT-KALMDICDQL-----EKNQTKMATYLAELLILNYGTHVIT 207
             ++ +    +      FT   LMD  + +       N    A Y        +GTHV++
Sbjct: 170 CSVFQLDLIDSPTYHAQFTNDILMDFQNLISIQGNSSNTEANAYYD---FFDKWGTHVVS 226

Query: 208 SVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYL 267
           SV+ G+    +  + +S +    N    V+ASA I      N +  T+   + +   ++ 
Sbjct: 227 SVNLGSLFGYKFQLLTSDIQSMNNQGIDVSASATI-----FNVRGRTNTQIEQNNLDNFS 281

Query: 268 SNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLV 327
            +       S G  P         W        + I  +  P H  +           ++
Sbjct: 282 QSIQKWTSYSIGATPDVNNDPAN-WASQTLTKPMPIKSSITPYHEALN--IFTQGNNSIL 338

Query: 328 KKLSKTVETAVRHYYTFNTHPG--CTNVDSPNFNFQANMDDDSCDAKVTN 375
           +         ++ YY    +    C+    PN        +   D   + 
Sbjct: 339 QS-----SQILQLYYKLRLYGNSYCSQRLLPNGQIDQCNSNSQSDYNFSQ 383


>UniRef50_D2WL87 MAC/perforin-and kringle-domains-containing protein (Fragment) n=1
           Tax=Pomatoceros lamarckii RepID=D2WL87_9ANNE
          Length = 579

 Score =  183 bits (463), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 48/295 (16%), Positives = 94/295 (31%), Gaps = 17/295 (5%)

Query: 50  GWDNLRNVDMGRVMDLTYTNCKT-TEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQ 108
           G+     VD G  M +   N +T T D +Y IP     I          SE + S   ++
Sbjct: 99  GYPLAHGVDPGFTMPIFAANFETYTYDCKYFIPSGFEVISVPACQTSFTSEEMRSEQEFK 158

Query: 109 STTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIY--TVKTTPTSE 166
            + + S +     +   +   + ++Q          ++    Q   + Y  T+       
Sbjct: 159 QSLATSASVNGGGWG-ASFSANVDYQSSMESMQSTNSIYMISQASCQSYQSTLHILNPPP 217

Query: 167 LSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFL 226
           L+  F KA+ D+         +   Y       ++GTH  T +D GA  + +  +     
Sbjct: 218 LNEFFVKAVEDLSQSEGSADEEEKYY---EFFKDFGTHYPTKMDFGARYINKHKINRQAY 274

Query: 227 LDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPG 286
              +   ++++ SA  ++  IV+        +      D       +   + G     P 
Sbjct: 275 --RKLQDSSLSVSAQASYEGIVSVSGSASATTSQKSAVDNFKEMVETETITMGS---LPS 329

Query: 287 ITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
             + +W   I +  V I      +                   L+  V   +  Y
Sbjct: 330 GDMGSWAASIKSTAVPIKYKLESIENLFTATFFKSRSA-----LAAAVRAKIIEY 379


>UniRef50_Q9U0J9 MAC/Perforin, putative n=8 Tax=Plasmodium RepID=Q9U0J9_PLAF7
          Length = 842

 Score =  181 bits (458), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 84/490 (17%), Positives = 150/490 (30%), Gaps = 63/490 (12%)

Query: 48  GGGWDNLRNVDMGR--------------VMDLTYTNCKTTEDGQYIIPDEVYTIPQKES- 92
           G G++ L    +G               +M+   +      D   + P   +   +    
Sbjct: 248 GIGYNLLFGNPLGEADSLIDPGYRAQIYLMEWALSKEGIANDLSTLQPVNGWIRKENACS 307

Query: 93  NLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQV 152
            +E  +E   S  +Y  + S       + +   +   ST +        K    T  V+ 
Sbjct: 308 RVESITEC-SSISDYTKSLSAEAKVSGSYWGIASFSASTGYSSFLHEVTKRSKKTFLVKS 366

Query: 153 RNRIYTVKTTP--TSELSLGFTKALMDIC--------------DQLEKNQTK---MATYL 193
               YT+   P    + +  +  A+ ++               D  E+N+TK       L
Sbjct: 367 NCVKYTIGLPPYIPWDKTTAYKNAVNELPAVFTGLDKESECPSDVYEENKTKSNCENVSL 426

Query: 194 AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVE 253
                  YGTH+I     G  + +  +V +S +   + +  +V A     F    +    
Sbjct: 427 WMKFFDIYGTHIIYESQLGGKITKIINVSTSSIEQMKKNGVSVKAKIQAQF-GFGSAGGS 485

Query: 254 TDYISQTSLTKDYLSNRTNSRVQSFGGVPFYP---GITLETWQKGITNHLVAIDRAGLPL 310
           TD  S  S   D  S   N ++   GG P         L  W K +TNH + I+    P+
Sbjct: 486 TDVNSSNSSANDEQSYDMNEQLIVIGGNPIKDVTKEENLFEWSKTVTNHPMPINIKLTPI 545

Query: 311 HFFIKPDKLPGLPGPLVKKLSKTVETAVRHY---YTFNTHPGCTNVDSPNFNFQANMDDD 367
                 D            L ++ + A+ +Y   Y  + H      D        N D  
Sbjct: 546 SDSFDSD-----------DLKESYDKAIIYYSRLYGLSPHDTMQKDDKDIIKILTNAD-- 592

Query: 368 SCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGY 427
                VT  +   +  +C    G V+      K     + +   GY+     + ++    
Sbjct: 593 ----TVTKNSAPPINAQCPH--GKVVMFGFSLKQNFWDNTNALKGYNIEVCEAGSNSCTS 646

Query: 428 SRLECKKK--CTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTI 485
            +    K     L + C            +E  + +         +  L FG   +   I
Sbjct: 647 KQGSSNKYDTSYLYMECGDQPLPFSEQVISESTSTYNTVKCPNDYSILLGFGISSSSGRI 706

Query: 486 NPMTNAQSCP 495
           N      S P
Sbjct: 707 NSAEYVYSTP 716


>UniRef50_Q23I78 MAC/Perforin domain containing protein n=2 Tax=Tetrahymena
           thermophila SB210 RepID=Q23I78_TETTH
          Length = 681

 Score =  166 bits (420), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 50/333 (15%), Positives = 106/333 (31%), Gaps = 45/333 (13%)

Query: 44  EVLPGG-----GWDN--LRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQ--KESNL 94
           E LPG      G+D   L N  +G+     +       +  + +  + Y +P   + + +
Sbjct: 20  ETLPGLDYIKSGYDGTKLLNDQLGQSKYPIFDLGPQNGESDFTVNGKTYKVPIMVQATQV 79

Query: 95  EMNSE-----VLESWMNYQSTTSLSINTELAL---FSRVNGKFSTEFQRMKTLQVKDQAV 146
            +  E     +  S+ ++Q   S SI+    L      ++   + E  +      ++   
Sbjct: 80  SLRKESQCEGIFYSFSDFQKKYSESISFSAGLGIENFSISLGINHELDQFHQEITQNNKA 139

Query: 147 TTRVQVRNRIYTVKTTPTS--ELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTH 204
            +  Q     Y++ T P     L+  F ++L  +    ++  T     +   +I ++GTH
Sbjct: 140 VSVSQSYWAQYSLTTAPAFLMPLNPMFKQSLDALNRMAKEPTTDTQQTIYNQVINSFGTH 199

Query: 205 VITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF-LNIVNFKVETDYISQTSLT 263
            +TS   G A      +  ++L              GI F  N+  FK   +        
Sbjct: 200 YVTSAIMGGAAKIYTTLDQNYLK--TVDIEQTKTQIGINFSYNVFQFKFGFNSTDLAQKL 257

Query: 264 KDYLSNRTNSRVQSFGGVPFYPGITL-------ETWQKGITNHLVAIDRAGLPLHFFIKP 316
            +     +N  +       F P +          TW+  +      ++     +      
Sbjct: 258 DENFKKNSNDII------IFSPEVDHISDPKAWSTWESTVPEKPQPVNTTVSYISDL--A 309

Query: 317 DKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPG 349
            + P         +   +   +  Y      P 
Sbjct: 310 YEFPE--------VQAHLRKTIEFYLRNGRLPS 334



 Score = 92.6 bits (228), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 47/304 (15%), Positives = 105/304 (34%), Gaps = 17/304 (5%)

Query: 48  GGGWDNLRNVDMGRVMDLTYTNCKTTEDG----QYIIPDEVYTIPQKESNLEMNSEVLES 103
           G G+D     D   + DL   N + +       ++ +P+ ++ + + ES     + +  +
Sbjct: 359 GCGYDATSLSDKRCIFDLEGENYQWSNPNDPTIEFNVPEMLFVMNKPESITLNGTTIFST 418

Query: 104 WMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRN-RIYTVKTT 162
           + ++   T      +   F    GK           ++        + +R    YT+K  
Sbjct: 419 FNDFVKETFWETREDSHGFLGFGGKHKRTQYHEYYEKIYQNYQKLALNLRQITWYTLKVP 478

Query: 163 --PTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDH 220
             P   L+  F +++  +    E N+     +     I  +GTHV+   D G  +  ED 
Sbjct: 479 TFPKPPLNKIFEQSIKMLP--TEFNEQNSQFF--NQFIEAFGTHVVIEGDFGGLVYAEDW 534

Query: 221 VRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG 280
             S  L  +   +  +       +     F+ ++   +            +       GG
Sbjct: 535 FESCLLNMH--DEIWIREEISKRYDPFGCFRKDSTKQTDVKQISVEFKQNSEFHALLLGG 592

Query: 281 VPFYPGITLETWQKGITNHLVAIDRAGLPLHFFI----KPDKLPGLPGPLVKKLSKTVET 336
               P    + W   +  +  A++R  +PL  F+    + D L      + ++ +   E+
Sbjct: 593 TDSIPLSDWDKWVPSVKYNPKALNRKLVPLTNFVPNGPQKDALSAAILAIRQQAASEQES 652

Query: 337 AVRH 340
            + +
Sbjct: 653 YISY 656


>UniRef50_P07357 Complement component C8 alpha chain n=23 Tax=Amniota
           RepID=CO8A_HUMAN
          Length = 584

 Score =  164 bits (415), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 71/459 (15%), Positives = 132/459 (28%), Gaps = 101/459 (22%)

Query: 32  QICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTY--TNCKTTEDGQ------------ 77
           + C     +P  +     G++ L   D   V D +Y    C+T  +G+            
Sbjct: 138 EDCSQYEPIPGSQK-AALGYNILTQEDAQSVYDASYYGGQCETVYNGEWRELRYDSTCER 196

Query: 78  -YIIPDEVYTIPQKE---------SNLEMNSEVLESWMNY--------QSTTSLSIN--- 116
            Y   DE Y               ++  ++SE  ++  +           +  ++I    
Sbjct: 197 LYYGDDEKYFRKPYNFLKYHFEALADTGISSEFYDNANDLLSKVKKDKSDSFGVTIGIGP 256

Query: 117 ------TELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLG 170
                   + +    +  F  E  +    +     + T+VQ  +            L  G
Sbjct: 257 AGSPLLVGVGVSHSQDTSFLNELNKYNEKKFIFTRIFTKVQTAHFK---MRKDDIMLDEG 313

Query: 171 FTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQ 230
             ++LM++ D       +    +    I +YGTH ITS   G        +  + +    
Sbjct: 314 MLQSLMELPD-------QYNYGMYAKFINDYGTHYITSGSMGGIYEYILVIDKAKMESLG 366

Query: 231 NSQNTVTAS----AGIAFLNIVNFKVETDYI--------SQTSLTKDYLSNRTNSRVQSF 278
            +   +T       GI + + +N                      K        SRV+  
Sbjct: 367 ITSRDITTCFGGSLGIQYEDKINVGGGLSGDHCKKFGGGKTERARKAMAVEDIISRVRGG 426

Query: 279 GGVPF------YPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSK 332
                         IT  +W + +  + V ID    P+H  ++   L  L         +
Sbjct: 427 SSGWSGGLAQNRSTITYRSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEA-----KRQ 481

Query: 333 TVETAVRHY-YTFNTHPGCTNVDSPNFNFQANMDDD-SCDAKVTNFTFGGVYQECTELSG 390
            +  A+  Y   FN          P FN    + +  SC  +    + G   ++      
Sbjct: 482 NLRRALDQYLMEFNACR-----CGPCFNNGVPILEGTSCRCQCRLGSLGAACEQTQTEGA 536

Query: 391 D-----------VLCQNLEQ--------KNLLTGDFSCP 410
                        +C+   Q             G  SCP
Sbjct: 537 KADGSWSCWSSWSVCRAGIQERRRECDNPAPQNGGASCP 575


>UniRef50_B0R0K6 Novel protein n=10 Tax=Clupeocephala RepID=B0R0K6_DANRE
          Length = 517

 Score =  162 bits (410), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 68/373 (18%), Positives = 122/373 (32%), Gaps = 61/373 (16%)

Query: 33  ICKNALKLPVLEVLPGGGWDNLRNVDMGRVM--------DLTYTNCKTTEDGQYIIPDEV 84
            C+ A  +P    L G G+D ++    G  +        + T T CK    G  +     
Sbjct: 34  ECEKAPFVPGYN-LAGEGFDVVKMRRKGAFLINVKSHIDNGTCTICKNRFQGGQMQKLPS 92

Query: 85  YTI---PQKESNLEMNSEVLESWMNYQSTTSLSINTELALF--------SRVNGKFSTEF 133
             +   P    + +++S +  S  +   +++  +N    +             G  S   
Sbjct: 93  AVLDWRPFSRCSKQLSSALHHSVDSLMKSSTSLVNNNWEMDLSLDDMGKVIFGGSRSDIA 152

Query: 134 QRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYL 193
           Q   +    D+A     ++    Y+ + T   ELS  F+K L  +  Q +         L
Sbjct: 153 QFAHSQNTMDKATFALHEISCTYYSYRITDNPELSAEFSKHLQKLPAQYD----AQTKPL 208

Query: 194 AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNF--K 251
               I  YGTH I  V  G  + +    R+        S+  +     +     + F   
Sbjct: 209 YRRTIETYGTHYIRQVHLGGRVRRVTAFRTCLATLKGFSETDIKNCLNVELKITLGFLPG 268

Query: 252 VETDYISQTSLTKD------YLSNRTNSRVQSFGGVPFYPGITLET--------WQKGIT 297
             +     + + KD      Y    T+ + +  GG  ++P + L          W   + 
Sbjct: 269 NASLSNKCSQILKDNLSMGFYQGFMTH-KTEVLGGEKYFPDLVLSQSPAEAYSNWMMSLH 327

Query: 298 NHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTH-------PGC 350
           N+   I  A  PLH  +     P         +S  ++ AV  Y   N          GC
Sbjct: 328 NNPDVISYAIFPLHHLVAD---PE--------VSSNLKIAVTEYIEENMISVDHKENQGC 376

Query: 351 TNVDSPNFNFQAN 363
           +   +PN +    
Sbjct: 377 SQ--TPNLDHNCC 387


>UniRef50_UPI00006A16E1 Perforin 1 precursor (P1) (Lymphocyte pore forming protein) (PFP)
           (Cytolysin). n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI00006A16E1
          Length = 519

 Score =  156 bits (394), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 53/381 (13%), Positives = 121/381 (31%), Gaps = 59/381 (15%)

Query: 33  ICKNALKLPVLEVLPGGGWDNLRNVDMGRVM---------DLTYTNCKTT--EDGQYIIP 81
            C  +  +P   +L G G+D +        +         +     C      + +  +P
Sbjct: 11  ECIKSTFIPGHSLL-GIGFDIVTLKRTEAYVIDMHRFSGKNKKCRVCNNPHKNNARQKLP 69

Query: 82  DEV-YTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA-----------LFSRVNGKF 129
             +    P    + ++ S+V  S ++     S  +  +             + + + G  
Sbjct: 70  LAIADWRPYSSCSRKITSDVSRSSVSLAEDASSGVQNDWKAGLELQAPVGNVKAVLAGSH 129

Query: 130 STEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKM 189
           S   + +++   +D+    R Q++   Y+++ TP   LS  F K L D+    +   T+ 
Sbjct: 130 SQLAKFVESKTNRDRYSFLRHQLKCLYYSLRLTPKPPLSNHFWKELQDLPKTYDTG-TQQ 188

Query: 190 ATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNS----QNTVTASAGIAFL 245
             Y     I  YGTH I+  + G  + +   +R+     +  S    ++ ++  A  +  
Sbjct: 189 TFYR---FIRVYGTHYISQAEVGGQVSEVTAIRTCQATMDGLSLDELKDCLSLEASASVT 245

Query: 246 NIVNFKVETDYISQTSLT----KDYLSNRTNSRVQSFGGVPFYPGITL-----------E 290
             +    E     + S      + +         Q  GG   +  ++             
Sbjct: 246 GKMEANAEAKTCKEMSQKATRGESFHKTFNEKDWQISGGKVTFDLLSFDVSKDGSTAAFG 305

Query: 291 TWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGC 350
            W + + +H   +  +   +H  ++                + +  A+  Y         
Sbjct: 306 EWMESLKSHPDIVTYSLESVHNLVR----------FKGPQKENLRKAISDYIMEKALR-- 353

Query: 351 TNVDSPNFNFQANMDDDSCDA 371
            N   P   +     + SC  
Sbjct: 354 KNCSCPGGTYPNQGAECSCVC 374


>UniRef50_O76288 Apextrin n=4 Tax=Echinoida RepID=O76288_HELER
          Length = 491

 Score =  156 bits (394), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 53/294 (18%), Positives = 99/294 (33%), Gaps = 18/294 (6%)

Query: 7   LVLIWM--IIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMG---- 60
           L+L  +  +I+   +  P+              +   +++  P G       VD G    
Sbjct: 12  LILFSLLPVISLGASTLPIPNPMKY------IGIGYNIIDGNPEGDNRVAGGVDPGLLVS 65

Query: 61  -RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTEL 119
            R+ +LTY N KTT D +Y +PDEV    +  S     ++      +Y    S  +  + 
Sbjct: 66  RRIFELTYDNGKTTNDNEYRVPDEVEFQQRSSSFTSKETDTFYGTKSYAKKLSHQVQADA 125

Query: 120 A---LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALM 176
           +   +F+ V    S  ++ +         V +  Q       ++   +     GF  A  
Sbjct: 126 SVEAVFASVKFSASHRYESISNDASTKGYVYSSEQTIQNFGHMRYLTSLAEHDGFEIARE 185

Query: 177 DICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTV 236
              D  +   T  AT      +  +GT V+T  D G           S  + + ++  + 
Sbjct: 186 FRIDVCDLPTT-YATNTYMEFLSKWGTSVVTEADVGVRTGINSREDRSSFVKDASTDMSN 244

Query: 237 TASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLE 290
           + S    +  I +  +  D    +          T     + G   F   IT+ 
Sbjct: 245 SVSVEGNYK-IFSASLSVDMDRFSQSASSEKKMGTEYTRYTIGSEEFNEPITIS 297


>UniRef50_UPI0000E49992 PREDICTED: similar to apextrin n=17 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E49992
          Length = 570

 Score =  155 bits (392), Expect = 4e-36,   Method: Composition-based stats.
 Identities = 57/332 (17%), Positives = 106/332 (31%), Gaps = 48/332 (14%)

Query: 40  LPVLEVLPGGGWDNLRNVDMG-----RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNL 94
             +LE  P GG      VD G     R+ +L+Y   K + DG Y +PDEVY + +  +  
Sbjct: 41  YNILEGNPEGGELGSGGVDPGLLVSRRIFELSYDESKVSSDGMYRVPDEVYFVSRDSAFT 100

Query: 95  EMNSEVLESWMNYQSTTSLSINTELALFSR---VNGKFSTEFQRMKTLQVKDQAVTTRVQ 151
             +        +Y S  S  ++   +            S  ++ +        +V    Q
Sbjct: 101 SSSRTTFHGTESYASKLSAQVDVAGSYSGTFASAEFAASARYETISNRMASQGSVFFATQ 160

Query: 152 VRNRIYTVKT------TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHV 205
               +   +         +  L+ GF      +      N    A Y+    + ++GTHV
Sbjct: 161 TIQNLGNARYLTELAQPNSYALNNGFVSDACSLP-----NSYNEADYM--QFLESWGTHV 213

Query: 206 ITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKD 265
           +T VD G  +        S  ++  ++Q + + SA  ++    +  +  +  S  S  + 
Sbjct: 214 VTEVDLGTRVGTNYEESRSSFVEYASTQVSASLSASGSYAG-YSASIAVNMDSFNSGMES 272

Query: 266 YLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL--- 322
             S  +     + G                       I    L +H     D    L   
Sbjct: 273 GSSFGSTYSSYTVGSASLNE----------------PIKLELLGMHEVFDEDYWTLLSSY 316

Query: 323 -------PGPLVKKLSKTVETAVRHYYTFNTH 347
                         +   V TA++ Y  + + 
Sbjct: 317 LDSGHCTSSFQRSSVGSNVLTAMQGYANYRSI 348


>UniRef50_Q1CW76 Putative uncharacterized protein n=1 Tax=Myxococcus xanthus DK 1622
           RepID=Q1CW76_MYXXD
          Length = 1392

 Score =  152 bits (384), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 45/209 (21%), Positives = 71/209 (33%), Gaps = 55/209 (26%)

Query: 369 CDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYS 428
           C+    +  FGG +                  N  TG  SCP GY+       TH   +S
Sbjct: 755 CELPAKSLDFGGAF--------GFFNNGTLSPNPATGAASCPEGYTKTQAY-GTHGRDWS 805

Query: 429 RLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPM 488
              C +                            +  G    + G ++G V      NP+
Sbjct: 806 VHFCHRPS--------------------------LEGGAPLYDFGGMWGYVNNTLVRNPI 839

Query: 489 TNAQSCPAGYIPLNLFESLKVCVSLDYELGFKF-----SVP----FGGFFSCIMGNPLVN 539
           TN+ +CPAGY    L  + ++    D+EL   +     + P    FGG +  +   P+ N
Sbjct: 840 TNSANCPAGYADQRLLGTNRL----DHELHVCYRPHAANTPEMARFGGMYGTVQAAPVPN 895

Query: 540 SDTAKDVRAPSLKKCPGGFSQHLAVISDG 568
             TA         +CP GF +   + +  
Sbjct: 896 PATAT-------TECPSGFEKTQVLGTSN 917



 Score =  109 bits (271), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 47/218 (21%), Positives = 69/218 (31%), Gaps = 57/218 (26%)

Query: 369 CDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYS 428
           C+ +     FGG +          L       N  TG  SCP GY+   +L  T    + 
Sbjct: 415 CEPRSDVLDFGGAF--------GRLNNGTLSPNPATGAASCPDGYTQTQVL-GTWGRDWD 465

Query: 429 RLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPM 488
              C++                                    + G ++G V     +NP+
Sbjct: 466 VHICQRPSR--------------------------EGSPPLYDFGGMWGYVNAQPVVNPI 499

Query: 489 TNAQSCPAGYIPLNLFESLKVCVSLDYELGFKF--SVP-------FGGFFSCIMGNPLVN 539
           T A  CPAGY    L  +     + DY L   +   VP       FGG    +   P+ N
Sbjct: 500 TQAARCPAGYTAQQLLGT----YNQDYGLHLCYRPHVPGRIPENRFGGIHGHVNQLPVAN 555

Query: 540 SDTAKDVRAPSLKKCPGGFSQHLAVISDGCQ--VSYCV 575
             T           CP G  +   + + G    V YC+
Sbjct: 556 PATGT-------TACPPGAVETQVLGTQGVDHPVYYCM 586



 Score =  102 bits (253), Expect = 6e-20,   Method: Composition-based stats.
 Identities = 46/226 (20%), Positives = 71/226 (31%), Gaps = 49/226 (21%)

Query: 380 GVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLEC--KKKCT 437
           GV                  +N  TG  SCP G+    +L  TH   Y    C  +    
Sbjct: 194 GVLSGYRFGGAHGFVNAAATQNPATGAASCPEGFEQTQVL-GTHNVDYPLYFCMARASHW 252

Query: 438 LKIFC----------------KTVCEDVFRV------AKAEFRAYWCVAAG----QVPDN 471
                                   C D +           +   + C        +   +
Sbjct: 253 DFGGFIGTRNGGEPVLNPVTDTENCPDGYSRTQVLGTGAVDQPLHLCARPNWDGTEPELD 312

Query: 472 SGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKF---------S 522
            G L+G V      NP TNAQ+CPAG+    +  ++      D+ L   +         +
Sbjct: 313 FGGLWGFVNDTAVKNPYTNAQNCPAGFTAQTVLGTM----GQDHNLHACYRPHVPGTGPT 368

Query: 523 VPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDG 568
           +PFGG +  + G+ + N  TA          CP GF+      + G
Sbjct: 369 LPFGGMWGHVEGSQVPNPVTATAS-------CPKGFTPKQVFGTSG 407



 Score = 96.9 bits (239), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 42/202 (20%), Positives = 59/202 (29%), Gaps = 55/202 (27%)

Query: 376 FTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKK 435
             FGG +          L       N  TG  SCP GY+   +L  T    +    C++ 
Sbjct: 82  LDFGGAF--------GRLNNGTLSPNPATGAASCPEGYTQTQVL-GTWGRDWDVHICQRP 132

Query: 436 CTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCP 495
                                              + G ++G V     +NP+T A  CP
Sbjct: 133 SQ--------------------------EGSPPLYDFGGMWGDVNAQPAVNPITQATRCP 166

Query: 496 AGYIPLNLFESLKVCVSLDYELGFKF--SVP-------FGGFFSCIMGNPLVNSDTAKDV 546
            GY    L  +     + DY L   +   VP       FGG    +      N  T    
Sbjct: 167 DGYTAQQLLGT----YNQDYGLHLCYRPHVPGVLSGYRFGGAHGFVNAAATQNPATGAAS 222

Query: 547 RAPSLKKCPGGFSQHLAVISDG 568
                  CP GF Q   + +  
Sbjct: 223 -------CPEGFEQTQVLGTHN 237



 Score = 88.4 bits (217), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 45/218 (20%), Positives = 70/218 (32%), Gaps = 57/218 (26%)

Query: 362  ANMDDDS--CDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLL 419
            +N+D     C A    + FGG            +       N +TG  +CP G+    + 
Sbjct: 916  SNVDHPLYFCMAHAPGWDFGGFI--------GSINGGETVPNPVTGTATCPDGHVQTQV- 966

Query: 420  SQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGV 479
            S T    +    C +                                +   + G L+G V
Sbjct: 967  SGTDSVDWPLSVCTRPNW--------------------------GDTEPALDFGGLWGYV 1000

Query: 480  FTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKF--SVP-------FGGFFS 530
              +   NP TNAQ+CPAG+    +  +       DY+L   +   VP       F G + 
Sbjct: 1001 NHNAVNNPYTNAQACPAGFQSQKVLGTH----GQDYDLHACYRPHVPGQRSPYAFAGMWG 1056

Query: 531  CIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDG 568
             + G    N  T+          CP GF+      + G
Sbjct: 1057 HVNGVQAPNPTTSAVS-------CPRGFAPTQVSGAQG 1087



 Score = 83.8 bits (205), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 37/180 (20%), Positives = 54/180 (30%), Gaps = 48/180 (26%)

Query: 369 CDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYS 428
           C  +   + FGGV+          L       N  TG  SCP GY    +   +      
Sbjct: 585 CMTRAPKWDFGGVF--------GYLNGGSPVSNPATGATSCPDGYVQTQVQ-GSSTMDAP 635

Query: 429 RLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPM 488
              C +                                +   + G ++G V      NP 
Sbjct: 636 LFLCSRPSW--------------------------DNAEPALDFGGMWGIVNGSWVNNPY 669

Query: 489 TNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFS---------VPFGGFFSCIMGNPLVN 539
           TN +SCPAG+  L +  +       D EL   +           PFGG +  +   P  N
Sbjct: 670 TNERSCPAGFAALKILGTA----GQDSELHLCYRHHAPGTVPPYPFGGMWGHVNDAPASN 725


>UniRef50_Q5BVJ5 SJCHGC08097 protein (Fragment) n=1 Tax=Schistosoma japonicum
           RepID=Q5BVJ5_SCHJA
          Length = 205

 Score =  152 bits (383), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 51/154 (33%), Positives = 69/154 (44%), Gaps = 23/154 (14%)

Query: 424 EEGYSRLECKKKCTLKIF-CKTVCEDVFRVAKAEFRAYWCVAAGQVPDNS--------GL 474
              YS   C +K   K   C T C        A   +YWC     +  +         G 
Sbjct: 2   RRCYSV--CNEKSWFKSRDCTTNC--------AITESYWCSRDPSLSSSPKVLDIDENGY 51

Query: 475 LFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMG 534
           LFGG++TDK +N +T   +CP  Y P+ L   +++C+S D ELG K+S+PFGGF+SC  G
Sbjct: 52  LFGGLYTDKEVNSLTKQYNCPQYYWPIALGRRMRICLSSDRELGGKYSLPFGGFYSCFSG 111

Query: 535 NPLV----NSDTAKDVRAPSLKKCPGGFSQHLAV 564
           NPL      + T K          P  F Q    
Sbjct: 112 NPLTGLINGNVTNKMDAEGKHAGMPEWFKQQQGR 145


>UniRef50_P14222 Perforin-1 n=27 Tax=Mammalia RepID=PERF_HUMAN
          Length = 555

 Score =  152 bits (383), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 53/313 (16%), Positives = 85/313 (27%), Gaps = 46/313 (14%)

Query: 90  KESNLEMNSEVLESWMNYQSTTSLSINTELAL------------FSRVNGKFSTEFQRMK 137
                 +    + S        + SI  +  +               V G  S       
Sbjct: 100 SGCQRHVTRAKVSSTEAVARDAARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAA 159

Query: 138 TLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELL 197
               +DQ   +   V  R Y+     T  L   F +AL D+      N +    YL   L
Sbjct: 160 QKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPDFKRALGDLPHHF--NASTQPAYL--RL 215

Query: 198 ILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYI 257
           I NYGTH I +V+ G  +     +R+  L     + N V     +     +         
Sbjct: 216 ISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAE 275

Query: 258 SQTSLTKDYLSNRTNSRVQSF--------GGVPFYPGITL----------ETWQKGITNH 299
           ++    K      T S  Q++        GG        L            W   +   
Sbjct: 276 AKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGS 335

Query: 300 LVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNT-HPGCTNVDSPNF 358
              +D    PLH  +                 + +  A+  Y T       C+    P  
Sbjct: 336 PGLVDYTLEPLHVLLDSQ----------DPRREALRRALSQYLTDRARWRDCSRPCPPGR 385

Query: 359 NFQANMDDDSCDA 371
             ++  D   C  
Sbjct: 386 Q-KSPRDPCQCVC 397


>UniRef50_Q254S3 Phospholipase D endonuclease n=13 Tax=Chlamydiaceae
           RepID=Q254S3_CHLFF
          Length = 813

 Score =  150 bits (377), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 41/257 (15%), Positives = 87/257 (33%), Gaps = 23/257 (8%)

Query: 116 NTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTP---TSELSLGFT 172
            ++  L        S  ++ ++    + +   T     + +Y +K        +L  GF 
Sbjct: 404 ESDGDLAQGAAFSLSVTYEFVQKSTHQAKNTVTCSTAAHSLYILKEDEGNSQKKLDSGFQ 463

Query: 173 KALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNS 232
             +     +L+ N         E  I  +GTH ITS   G    Q   +    + + Q+ 
Sbjct: 464 SWVET---KLKVNDPS----SFEAFIQRFGTHYITSATYGGMGFQALKLSFQQVEELQSQ 516

Query: 233 QNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPF----YPGIT 288
           + ++  +A  +       K       ++  +     + +++     GG          + 
Sbjct: 517 KISLETAAANSL-----IKGSVSNQVESGYSSYDSKSSSHTVF--LGGTVLPSMKDEHLD 569

Query: 289 LETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHP 348
              W + +    V I  + LP+   +  D  P      + +  K+++ AVR Y     H 
Sbjct: 570 FTEWSESVRLEPVPIQVSLLPIADLLTTDFFPKENQDTLAQKKKSLKQAVRVYLK--KHK 627

Query: 349 GCTNVDSPNFNFQANMD 365
                +   F   AN++
Sbjct: 628 TSERKERAVFTSGANVN 644


>UniRef50_A0BCZ0 Chromosome undetermined scaffold_10, whole genome shotgun sequence
           n=2 Tax=Paramecium tetraurelia RepID=A0BCZ0_PARTE
          Length = 603

 Score =  149 bits (376), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 43/287 (14%), Positives = 95/287 (33%), Gaps = 14/287 (4%)

Query: 62  VMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTEL-A 120
           +   +Y+  + T DG++ IPD +  I +K       S V+++    Q+  S  I   L +
Sbjct: 82  IFLTSYSKKQVTSDGRHKIPDNLNVITKKGCKYNFESFVIKNTEQIQNYMSSFIGVNLVS 141

Query: 121 LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSEL---SLGFTKALMD 177
                   F+   +     Q  +Q   T V         + T   EL      F   L  
Sbjct: 142 NIDITPWAFTASSEFNHMQQKIEQTSATFVISMATCQIAQITQVPELAEFHQSFIDQLSA 201

Query: 178 ICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT-- 235
           +   +E +  +   +L+      +GTH  T +  G+ +     +  + + D    +    
Sbjct: 202 LP--VEYSAPQYLEFLSN-----FGTHYATDIILGSKVGYVYTLPPAIVDDFDQKKFKEI 254

Query: 236 -VTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQK 294
            +  +A I    +     +     +         ++ +++  +    P     T + W +
Sbjct: 255 DLKQAATITSALLKGVIGQQILPKEQEAKAYSDVSKLSTQSFTIEIGPQSTENTPKDWLR 314

Query: 295 GITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
                   I      +   +   K         +K+ + ++ A+  Y
Sbjct: 315 ETELEPTPIRYTLKSISELVSEGKGQLSSVKEYQKIGQNLKKALTDY 361


>UniRef50_C4JX95 Predicted protein n=1 Tax=Uncinocarpus reesii 1704
           RepID=C4JX95_UNCRE
          Length = 722

 Score =  145 bits (364), Expect = 7e-33,   Method: Composition-based stats.
 Identities = 45/269 (16%), Positives = 82/269 (30%), Gaps = 39/269 (14%)

Query: 73  TEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTE 132
           + D  Y +P  +       S     +   E+   +    S ++N     F+   G+FS  
Sbjct: 244 SGDSTYTVPGYMTFSWASTSTSMTIA--GETKTKFIQELSRTLNVGAD-FAGFGGEFSRT 300

Query: 133 FQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATY 192
           +     ++   +            Y      T    LGF           E       ++
Sbjct: 301 YDDSSKVETWKK------------YMATYHQTLIYRLGFKDIDQAKTYLTETATEAFKSW 348

Query: 193 LAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKV 252
            AE +I  +GTH + S   G   +    + +SF                           
Sbjct: 349 SAEKIIHTFGTHYMISATFGGIRITSSSLDASFSGPETE------------------LDA 390

Query: 253 ETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHF 312
                S+    +  +S     R ++ GGV     +  + W+  + ++ V +D    P+  
Sbjct: 391 NAKNSSKDQTVQQIMSKMELVRTRTIGGVADDSNV--QAWRNSLYSNPVVVDYDIRPIWE 448

Query: 313 FIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
            I    L G     VK     + TA + Y
Sbjct: 449 LIDDQNLAGQ----VKTQVNALLTAAQPY 473


>UniRef50_B6Q8L9 Putative uncharacterized protein n=1 Tax=Penicillium marneffei ATCC
           18224 RepID=B6Q8L9_PENMQ
          Length = 784

 Score =  144 bits (363), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 34/260 (13%), Positives = 82/260 (31%), Gaps = 13/260 (5%)

Query: 90  KESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAV-TT 148
           K     + S +  +W +  ++ S+   ++    ++++ K +            ++    T
Sbjct: 243 KTVQFSVPSYLTMTWGSESTSFSIVGESKKEFTNKLSKKLNLGGDFFGFGGEFERTFDET 302

Query: 149 RVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITS 208
           R +   + Y  +       S+ F           +     M T+    ++ ++GTH    
Sbjct: 303 RTEETFKKYMARYNQEVVYSVSFKDEDNAAKYLSDDALVAMKTWTPAKIVASFGTHYTVQ 362

Query: 209 VDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLS 268
              G + +    + +    +   ++ +        F +           + TS T D   
Sbjct: 363 ATIGGSRILASSLDTR--DEFTETEMSTAIDLKAKFKDSKG-GDAGSINAGTSSTSDKSQ 419

Query: 269 NRTNSR----VQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL-- 322
               S       + GG        L +W++ +T +   I+    P+   +  D       
Sbjct: 420 KLFESLHTINTHTIGGTATDDNENLNSWRQSLTTNPALINYKLRPIEELVPADLTVEQGK 479

Query: 323 ---PGPLVKKLSKTVETAVR 339
                P++      V+ A R
Sbjct: 480 DDTGKPVMASKRGLVKKAAR 499


>UniRef50_UPI00006CCD2A MAC/Perforin domain containing protein n=1 Tax=Tetrahymena
           thermophila RepID=UPI00006CCD2A
          Length = 387

 Score =  144 bits (362), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 41/282 (14%), Positives = 96/282 (34%), Gaps = 19/282 (6%)

Query: 74  EDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL-FSRVNGK--FS 130
           E   Y +   V    +          V  S+ ++Q   + SI+ +  +    +     F+
Sbjct: 67  EGKTYKVSQVVQATSELTRKEVTCENVYTSFTDFQKKLTESISIQGGIQIGDIKASLGFN 126

Query: 131 TEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTS--ELSLGFTKALMDICDQLEKNQTK 188
              + +     K+    T  Q     Y++  +P     L+  F +AL  + + ++  Q +
Sbjct: 127 HSLEEIYEKITKEGKSVTMSQSYWSKYSLTNSPAFLMPLNNQFKRALEYLNENVKIPQDQ 186

Query: 189 MATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLL--DNQNSQNTVTASAGIAFLN 246
                   ++  YGTH ++S+  G        + ++++   D Q  +N V         N
Sbjct: 187 NGQTFYNQVVQAYGTHYVSSIVMGGTAKILTLLNTTYVETHDFQEVKNQVNLEVNYIMSN 246

Query: 247 IVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRA 306
            +NF    +  ++ + +  Y  +  N    +            + W+  +  +   ++  
Sbjct: 247 -LNFDASFN-QTENTTSVVYQKDAENYIFFTPDLSHSKEEKAWDAWESRVPQNPQPVN-- 302

Query: 307 GLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHP 348
                  I    L  L     K++ + +   + +Y      P
Sbjct: 303 -------ITVSYLSDL-ASSYKEVQQHLRDTIEYYLKNGDVP 336


>UniRef50_D0ZYB6 MAC/perforin domain protein n=1 Tax=Chlamydophila pneumoniae LPCoLN
           RepID=D0ZYB6_CHLPP
          Length = 818

 Score =  140 bits (351), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 34/250 (13%), Positives = 80/250 (32%), Gaps = 19/250 (7%)

Query: 100 VLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTV 159
           +  S          S   E +  S  +  FS  ++ +K+   + +   T       +Y +
Sbjct: 397 LGSSSEEDDDPMDESDGEEASKDSAFSASFS--YEFVKSSTRESKNTVTHSTASRTLYIL 454

Query: 160 KTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQED 219
           +            K   +    +EK             +   GTH +TSV  G    Q  
Sbjct: 455 R--QDCSYDPRALKVDDEFRYWVEKRLDAKNPDSLNAFVKEVGTHYVTSVTYGGIGFQVL 512

Query: 220 HVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSF- 278
            +    + + +  + +++ +A  +              +  +  K Y S ++ S  Q+  
Sbjct: 513 KMSYLQVEELEKEKISISVAAASSL---------LKSKTSNATEKGYSSYQSESSAQTVF 563

Query: 279 -GGVPF----YPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKT 333
            GG          +  + W + + N  + +  +   +   I P+  P     ++ +    
Sbjct: 564 LGGTVLPDLQQDKLDFKDWSESVPNEPIPLAISVSSITDLIIPELFPSEDAQVLSQKKSA 623

Query: 334 VETAVRHYYT 343
           +   + +Y  
Sbjct: 624 LGKVILNYLE 633


>UniRef50_UPI0000E48CEE PREDICTED: similar to apextrin n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E48CEE
          Length = 587

 Score =  137 bits (344), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 51/326 (15%), Positives = 102/326 (31%), Gaps = 42/326 (12%)

Query: 20  DKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMG-----RVMDLTYTNCKTTE 74
            +PL     TG +     +   +++  P GG   L  VD G      ++ LTY   + T 
Sbjct: 36  GEPL--PTPTGIRNFIG-VGYNIIDGNPEGGDIYLGGVDPGLLVTRPILKLTYDENQLTS 92

Query: 75  DGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTEL---ALFSRVNGKFST 131
           D +YI+PD+V   P+         +       Y    S+ +        +FS+     S+
Sbjct: 93  DREYIVPDQVLFSPRSSCVTTETQQTFYGTETYVEKISVDMKESGRVKTIFSKHKFSKSS 152

Query: 132 EF-------QRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEK 184
            +       +  + +  +D+ V    Q R     +       L  GF  +   +   L  
Sbjct: 153 RYEEINRGVETNRYVYYEDRTVCNMGQARY-RSELAMYEQYPLDTGFVYSACHLP--LTY 209

Query: 185 NQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF 244
           ++           I ++GTHV+T VD G+             +    ++   + +     
Sbjct: 210 DEETYMQ-----FIDDWGTHVVTKVDLGSKSTVRFAESREDFVHFARTEVEGSVTFRTKI 264

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAID 304
           +      ++ D     +         ++    + GG                      I 
Sbjct: 265 ITGYRGALKVDTDVFETGLSTGQKFGSHLSNFTSGGDEL----------------PEPIA 308

Query: 305 RAGLPLHFFIKPDKLPGLPGPLVKKL 330
              + +H     D        + ++L
Sbjct: 309 VELIGMHEVFDKDFWQEYSDYIKRRL 334


>UniRef50_Q32N46 LOC495232 protein n=3 Tax=Xenopus RepID=Q32N46_XENLA
          Length = 532

 Score =  135 bits (340), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 65/424 (15%), Positives = 126/424 (29%), Gaps = 59/424 (13%)

Query: 33  ICKNALKLPVLEVLPGGGWDNLRNVDMGRVM--------DLTYTNCKTTEDGQ--YIIPD 82
            C  A  +P    LP  G D +     G ++        + T   C+ ++D    + +P 
Sbjct: 33  QCLKASFVPGHN-LPARGIDIVTMKSAGNILFNTQQYMKNNTCKLCQDSQDKDKWWKLPR 91

Query: 83  EVY-TIPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL-----------FSRVNGKFS 130
            +     Q      M S+VL+S +      +  +  +                 + G  S
Sbjct: 92  ALEQWNMQSSCRRTMVSKVLQSPVLVAKEVASRVQNDWTNDLNLTCTELQGNVAMAGAQS 151

Query: 131 TEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMA 190
              Q        D+      +     Y+ + +    LS  F KAL+ + +    N     
Sbjct: 152 KMVQFAFEKLHLDKYTFLSHKFECEYYSFQMSRHWNLSPHFLKALVQLPNYY--NSRSNV 209

Query: 191 TYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNF 250
            Y  + LI +YGTH IT    G  L +   +R+  +  + ++   V        +  V  
Sbjct: 210 QY--QQLIASYGTHYITDATMGGQLQEVTALRTCEVALSDSTMQLVKDCREAEIMAAV-- 265

Query: 251 KVETDYISQTSL----------TKDYLSNRTNSRVQSFGGVPFYPGITL----ETWQKGI 296
            V  +    + +            ++         +  GG   +           W K  
Sbjct: 266 -VGPNNTMLSQICVPSTRKYIYVGNFHQGFNERFREVAGGNAMFDLHNHLSGENKWLKST 324

Query: 297 TNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSP 356
                 ++ + +P+H  I                 +++  A+  Y    +          
Sbjct: 325 EKDPALLNYSLMPIHTLINSRS----------PKRESLRIALSEYIKKRSLK--IECPCS 372

Query: 357 NFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDF-SCPPGYSP 415
              + +  +D SC    + +T        T      L   +     L GD+ S    Y  
Sbjct: 373 GNTYPSQREDCSCSCSPSKYTNSDCCP--TRKGLAKLIIEIRSATGLNGDYFSSTDSYVN 430

Query: 416 VHLL 419
            +  
Sbjct: 431 FYFN 434


>UniRef50_UPI00005841B7 PREDICTED: similar to apextrin n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI00005841B7
          Length = 613

 Score =  135 bits (340), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 43/263 (16%), Positives = 86/263 (32%), Gaps = 20/263 (7%)

Query: 40  LPVLEVLPGGGWDNLRNVDMGR-----VMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNL 94
              +   P G   N   VD G      + +LTY   K ++D +Y +PDE   + +  +  
Sbjct: 40  YNFIMGNPEGDSLNSGGVDPGLLASRNIFELTYDLGKKSKDNKYRVPDETEFLQRSSAFT 99

Query: 95  EMNSEVLESWMNYQSTTSLSINTELAL---FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQ 151
                      +Y  T S  +    +L   F+ V    S +++++   + K+  V    Q
Sbjct: 100 TKEKSTFHGTKSYAKTLSSKVQESASLDAVFASVKFAGSHDYKQISEDEKKEGYVYFTEQ 159

Query: 152 VRNRIYTVKTT------PTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHV 205
               + T++           E++  F   +  +    E  +           I  +GTHV
Sbjct: 160 TIQNLGTIRYLDELARADQFEITRNFYADVCGLPVTYESQKKNYMD-----FIDKWGTHV 214

Query: 206 ITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKD 265
           +T +  G           S  +   + Q + + S    +  I +  +  +    T     
Sbjct: 215 VTELQTGVRSGTTYRATRSSFVKLASEQRSDSLSLEGHYK-IASASISVNMDKFTEDKSA 273

Query: 266 YLSNRTNSRVQSFGGVPFYPGIT 288
                +       G    +  I+
Sbjct: 274 EKKFGSQYTTYKVGSETLHEPIS 296


>UniRef50_A7RF42 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RF42_NEMVE
          Length = 967

 Score =  130 bits (326), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 47/305 (15%), Positives = 88/305 (28%), Gaps = 29/305 (9%)

Query: 74  EDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEF 133
            DG   +PD +      +++  M +    S   YQS          + F    G      
Sbjct: 99  YDGD-QVPDTMNVHGIYDTSANMYT--FSSRSEYQSYLEKEAGVSGSYFGFYAGVKKAWG 155

Query: 134 QRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYL 193
               +      ++     VR  I+  +  P ++LS  F +  M++           A   
Sbjct: 156 NSFSSNVQSFLSIFDIDVVRYEIFKDEVKP-ADLSQAFLQEFMNLPPSYFHPGAGQA--- 211

Query: 194 AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVE 253
            +  IL +GTH I S   G  L      R +    +  ++   +      +  +      
Sbjct: 212 YQEFILRWGTHYIKSAKFGGEL----EFRKTLQGMSIATKEQASEVVEAEYKGLF-ASAG 266

Query: 254 TDYISQTSLTKDYLSNRTNSRVQSFGG---------VPFYPGI--TLETWQKGITNHLVA 302
             Y S++       +  ++S V   GG           + P      ++W   I  +  A
Sbjct: 267 AKYESKSGQESKSENKFSSSSVVVQGGSQEIAAILSDEYSPTFKEEFKSWLNSIQQYPKA 326

Query: 303 IDRAGLPLHFFIK---PDKLPGLPGPLVKKLSKTVE---TAVRHYYTFNTHPGCTNVDSP 356
                 P+   +     D  P            ++E        Y        C      
Sbjct: 327 FKFHMAPITDLVNFRAGDLFPEEDTVGCDVNGNSLEIDDNNQPFYMKEGKKVTCPFKSRS 386

Query: 357 NFNFQ 361
           + + Q
Sbjct: 387 DLDSQ 391


>UniRef50_B5X1M0 Perforin-1 n=2 Tax=Salmoninae RepID=B5X1M0_SALSA
          Length = 589

 Score =  129 bits (323), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 75/450 (16%), Positives = 132/450 (29%), Gaps = 66/450 (14%)

Query: 33  ICKNALKLPVLEVLPGGGWDNLRNVDMGRVM---------DLTYTNCKTTE--DGQYIIP 81
            CK A   P    L G G+D  +    G  +         D T T C+       +  +P
Sbjct: 31  ECKEAEFAPG-TNLAGEGFDITKMKRKGAFVIDMNVWKRKDKTCTLCENPYLEGKKQRLP 89

Query: 82  DEV-YTIPQKESNLEMNSEVLESW------------MNYQSTTSLSINTELALFSRVNGK 128
             V    P  + +++++S++  S              N+Q    L   ++   F  + G 
Sbjct: 90  LAVVDWRPNHQCSMKVSSKLHRSSESLVSSSSSSVENNWQVNLELEKGSKSGKF-MLAGT 148

Query: 129 FSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTK 188
            S   +        D+   T   V    Y+ + +   +L   F  A+ ++    +  Q  
Sbjct: 149 NSKLAEYSMEKTKSDKFSFTSHSVSCGYYSYRVSGQPKLHREFKTAVKNLPKIYQ--QEN 206

Query: 189 MATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTAS----AGIAF 244
              Y    LI N+GTH IT V  G  +     +          S   V       A  + 
Sbjct: 207 KQRYY--KLIDNFGTHYITKVSLGGTVQSVTSIMQCQASLQGLSAEEVKMCLDVEATASV 264

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRTNS----RVQSFGGVPFYPGITLE---------T 291
            +  + K E  +  +     +  ++ ++       +  GG    P +             
Sbjct: 265 GDSNSLKTEFKHCQEDKSKTESKASFSSVFNDRFTEVKGGHTTEPELLFSAEKDPASYKQ 324

Query: 292 WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNT-HPGC 350
           W   +  +   +  +   LH  +          P      K +  A+  Y   N     C
Sbjct: 325 WLDSLPRYPDIVSYSLESLHELL----------PTTNPARKHLRKAISDYILENALWKNC 374

Query: 351 TNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQEC--TELSGDVLCQNLEQKNLLTGDF- 407
           +               DSC     N    GV  +C  T      +   +++   L GD  
Sbjct: 375 SEPCQTGIKSDHR---DSCVCSCHNNP--GVSADCCPTRKGLARVIITVQRGANLWGDHT 429

Query: 408 SCPPGYSPVHLLSQTHEEGYSRLECKKKCT 437
           +   GY  V     T               
Sbjct: 430 TATDGYVKVAFAGLTIGRTRVIYNNNNPSW 459


>UniRef50_UPI000176082E PREDICTED: similar to perforin 1 (pore forming protein) n=6
           Tax=Clupeocephala RepID=UPI000176082E
          Length = 933

 Score =  129 bits (323), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 65/401 (16%), Positives = 123/401 (30%), Gaps = 59/401 (14%)

Query: 7   LVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMG--RVMD 64
           L++ W ++  A +    GE      + C+NA  +P    L G G+D +     G   +  
Sbjct: 367 LLVFWAMLLIAIS----GEVEIGTLKECENAHFVPGYN-LAGEGFDVVTLERKGTYVINT 421

Query: 65  LTYTNCKTTED---GQYI------IPDEV-YTIPQKESNLEMNSEVLESWMNYQSTTSLS 114
             +     T +    QY+      +P  V +     + +++++ ++ ES       +S +
Sbjct: 422 EKWDLGNGTCNMRTNQYMNGIKQKLPAAVDFWRTLPKCSMKVSGQIFESSEAVVEESSSA 481

Query: 115 INTELALF-------SRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSEL 167
           I+ +           + V G  S E +       +D+   T+ QV    Y         L
Sbjct: 482 ISGDWKADLSVKLSGATVGGTHSREAKFAMQKSKRDKYSFTKHQVECNFYRYHVVQKPPL 541

Query: 168 SLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLL 227
              F +A+  +    +        +    LI  YGTH  TSV  G  +     +++    
Sbjct: 542 HAEFLQAIKLLPASYD-------KFAYRSLISTYGTHYTTSVMLGGHMKAITAIKTCEAS 594

Query: 228 DNQNSQNTVTASAGIAFLNIVN---FKVETDYISQTSLT----KDYLSNRTNSRVQSFGG 280
               S   +     +    I      + E     +            S  +  + +  GG
Sbjct: 595 IGGLSDTAIKDCLDVEASGIYKALTVEAEARLCRELKQKLGTNLKMSSKFSERQTEIIGG 654

Query: 281 VPFYPGITLE---------TWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLS 331
                 +             W + + +    +     PLHF +                 
Sbjct: 655 KINGEDLLFSGSSHKNALKGWLESLKSVPDVVQYTLKPLHFLLSDK----------HPAR 704

Query: 332 KTVETAVRHYYTFNTHPG-CTNVDSPNFNFQANMDDDSCDA 371
           K ++ AV  Y   N     C+          A  D   C  
Sbjct: 705 KGLKKAVEEYIIENALRKVCSEPCKLGKKSSAR-DPCVCVC 744


>UniRef50_Q4SUR7 Chromosome undetermined SCAF13844, whole genome shotgun sequence.
           (Fragment) n=7 Tax=Clupeocephala RepID=Q4SUR7_TETNG
          Length = 517

 Score =  127 bits (318), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 66/378 (17%), Positives = 115/378 (30%), Gaps = 52/378 (13%)

Query: 30  GFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMD--LTY------TNCKTTED----GQ 77
            F  C+ A  +P   ++ G G+D +     G  +     Y       NC    +      
Sbjct: 18  SFTECQQAPFVPGHSLV-GEGFDVVTMKSSGASVVDVKNYMVGGAQGNCTVCHNPLLNQT 76

Query: 78  YIIPDEVYTIPQKE-SNLEMNSEVLESWMNYQSTTSLSINTELALF--------SRVNGK 128
             +P  V     K      ++S++ ES        S S++    +         + V G 
Sbjct: 77  QKLPVSVLDWRVKVMCQRSLSSKIFESSQEVMKEASSSLSVSWKVGLSLPLIGGAAVGGS 136

Query: 129 FSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTK 188
            S   Q   +   KD+   T   ++   YT +      LS  F ++L ++    +   T 
Sbjct: 137 HSRSSQFASSHSRKDKFSFTTHNLKCSYYTFRIHSRPPLSKEFEESLKNLPSTYDHKNTS 196

Query: 189 MATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFL-NI 247
                    +  YGTH I  V  G  +     +R+     +Q S  TV+    +    NI
Sbjct: 197 ----AFTQFLSVYGTHFIRRVRLGGHVNSITAIRTCQASMSQMSVQTVSNCLSVEAQANI 252

Query: 248 VNFKVETDYISQTSLTKD------YLSNRTNSRVQSFGG------VPFYPGIT--LETWQ 293
               V        + +        +    ++  ++  GG      V F        + W 
Sbjct: 253 KGVTVSAATQFCKTKSSKLKTGATFRQAFSDRSIEVLGGDGDVGDVLFNSNGVAGFKKWL 312

Query: 294 KGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNV 353
             I      +     PLH  +     P  P      L +T+  A+ HY +          
Sbjct: 313 ASIKRVPGLVWYQISPLHLLV-----PDNPV-----LQETLSKAISHYISTRA-RSLKCP 361

Query: 354 DSPNFNFQANMDDDSCDA 371
            +     Q       C  
Sbjct: 362 AACQSGHQNRNCACHCKG 379


>UniRef50_B5X3H3 Perforin-1 n=1 Tax=Salmo salar RepID=B5X3H3_SALSA
          Length = 597

 Score =  126 bits (315), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 64/413 (15%), Positives = 121/413 (29%), Gaps = 66/413 (15%)

Query: 9   LIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYT 68
           L+W+  A          TG      CK AL  P    L G G+D +   +  +   +   
Sbjct: 11  LLWLWGAWLSPVLSSCTTGRPA--ECKAALSAPG-TNLAGEGFDVVTM-ERKQAYVIDVD 66

Query: 69  NCKTTEDGQYIIPDEVYT--------------IPQKESNLEMNSEVLESWMNYQSTTSLS 114
             + T +G   +    +                P ++ N+++ S V +S   + S++   
Sbjct: 67  TWRKTGNGTCTLCVNPFMDRQAQRLPAAVVDWRPSQKCNMKLASMVYDSSEAFVSSSQTE 126

Query: 115 INTELAL-----------FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTP 163
           ++    +              V G  S   + + +   KD+    +  +    Y+ +   
Sbjct: 127 VDVSWKIGLDIMTPQAKGSVMVGGTHSRAAKTVMSQSKKDKYSFIKQDIHCSYYSYRLLD 186

Query: 164 TSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRS 223
              L   F+++L  +        T          + N+GTH I  V  G  +     +R 
Sbjct: 187 DPPLHPEFSRSLGLLPPLY----TDKTKVDYRRFLDNFGTHFIKKVLLGGRVKSVTSLRV 242

Query: 224 SFLLDNQNSQNTVTASAGIAF-----LNIVNFKVETDYISQT----SLTKDYLSNRTNSR 274
                +  ++N V                  FK ET +  +          + S      
Sbjct: 243 CQAALSGYNENEVKDCLEAEASVATSTGSAEFKTETKFCKKDLKKRDTKDRFSSTFQERF 302

Query: 275 VQSFGGVPF-YPGITLE----------TWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLP 323
            +  GG     P +              W   +      I+ +  PLH  +K        
Sbjct: 303 TEVVGGETDGTPDLLFSQTGGNSKAFADWASSLKTIPDVINYSLHPLHLLVKQGS----- 357

Query: 324 GPLVKKLSKTVETAVRHYY-TFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTN 375
                     ++ AV  Y         C+       +  A+ D   C  K + 
Sbjct: 358 ------KRAGLKKAVEDYILGHALVKRCSGKCKGGSSSSAH-DSCQCVCKASK 403


>UniRef50_Q7ZZH8 Perforin n=7 Tax=Clupeocephala RepID=Q7ZZH8_PAROL
          Length = 587

 Score =  124 bits (310), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 57/321 (17%), Positives = 99/321 (30%), Gaps = 38/321 (11%)

Query: 125 VNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEK 184
           + G  S   +       KD+   T   +    Y+ + + T +L   F KA+  +  +   
Sbjct: 145 LAGAHSKVAEYSMEKTKKDKFSFTSQSISCEYYSYRVSNTPKLHKEFKKAVKQLPKEYSS 204

Query: 185 NQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF 244
            ++K   Y    LI N+GTH IT V  G ++     +R         S   V        
Sbjct: 205 -ESKQQFY---NLIDNFGTHYITKVKLGGSVESVTSIRQCQASLEGLSVEEVQMCLEAEA 260

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRTNSR------VQSFGGVPFYPGITLE-------- 290
                 +V+              S  + S        +  GG    P +           
Sbjct: 261 SATFVVEVKAQNKFCKRDANKMESKSSFSSHFGDRFTEIKGGHTTEPDLLFSADKDPSAY 320

Query: 291 -TWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYY-TFNTHP 348
             W   +  H   +  +   LH  +          P    L K + +A+ HY        
Sbjct: 321 KEWLTTLPEHPDILSYSLKSLHELL----------PRNPPLQKNLRSAISHYILEKGLLR 370

Query: 349 GCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQEC--TELSGDVLCQNLEQKNLLTGD 406
            C+          +   D  C  +  N     V Q C  T +    +   +++   L GD
Sbjct: 371 NCSESCRAGIKSGS--KDP-CVCQCHNDP--AVNQNCCPTRVGMAQVIITVQRATGLWGD 425

Query: 407 F-SCPPGYSPVHLLSQTHEEG 426
             +   GY  V L ++  ++ 
Sbjct: 426 HTTSTDGYVKVSLDTKLVQQS 446


>UniRef50_A7AVA8 MAC/perforin domain containing protein n=1 Tax=Babesia bovis
           RepID=A7AVA8_BABBO
          Length = 978

 Score =  124 bits (310), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 41/339 (12%), Positives = 97/339 (28%), Gaps = 43/339 (12%)

Query: 35  KNALKLPVLEVLPGGGWDNLRNVDMG------------RVMDLTYTNCKTTEDGQ-YIIP 81
           +    L       G G+D +    +G             V+ L ++      DG     P
Sbjct: 319 RLNPGLAAAMRYLGSGYDIIYGNPLGDPVIMVDPGYRHPVLRLDWSEKYYNNDGANMKEP 378

Query: 82  DEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQV 141
              +  P+       + + + +  +Y+   S+       +    +   S  ++ M     
Sbjct: 379 KGGWIRPELSCRQSESVDHINTMDDYKKELSVDAKMSADMPLYFSFSASAGYKNMVRTLA 438

Query: 142 KDQAVTTRVQVRNRIYTVKTTPTSELSL--GFTKALMDICDQLEKNQTKMATYLAE---- 195
            ++     ++     Y         +     F   +  + ++    +  +  Y  +    
Sbjct: 439 TNETKNYILKTYCLRYVAGIQDFLNIEPTESFVYDVSQLPEKFHDGECLLEVYRNDPEDE 498

Query: 196 ----------LLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFL 245
                          YGTH  T +  G  +  +  +    +   Q     +        +
Sbjct: 499 KCASVVRPWMKFFQKYGTHFTTVIHLGGKVTNQIQIDKKDVAKLQKDGYNIDVMIKSGSI 558

Query: 246 NIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPG---ITLETWQKGITNHLVA 302
           + V       +  +   + ++ S +T   V   GG     G    T+  W K +    + 
Sbjct: 559 SPVKVGGGFSHEKKEESSSNFSSLQTEKLVIVIGGDVPTDGTDKTTMLEWTKSLYRKPMP 618

Query: 303 IDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
           I      +   I              +  K+ +TA+++Y
Sbjct: 619 IKVNIESIKTLIDG-----------HEKKKSFDTALKYY 646


>UniRef50_Q4N9F0 Putative uncharacterized protein n=2 Tax=Theileria
           RepID=Q4N9F0_THEPA
          Length = 1182

 Score =  123 bits (308), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 43/324 (13%), Positives = 102/324 (31%), Gaps = 36/324 (11%)

Query: 25  ETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMG------------RVMDLTYTNCKT 72
           +      Q+  N   L       G G+D +    +G             V+ L + +   
Sbjct: 570 DPRDP--QMDWNNSGLAASMRYLGSGYDIIFGNPLGDPVVMMDQGYRNPVIRLNWEDEYL 627

Query: 73  TEDGQYI-IPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFST 131
            +DG  +  P   +  P+         + + +  +++   S+       +    +   ST
Sbjct: 628 NKDGANLKEPRGSWIRPEYSCRQSETIDHVNTVDDFKKELSVDAQASYGIPYFFSFSAST 687

Query: 132 EFQRMKTLQVKDQAVTTRVQVRNRIYTVKT--TPTSELSLGFTKALMDICDQLEKNQTKM 189
            ++        ++  T   +     Y        + + +  F KA+  + D+ + +   +
Sbjct: 688 GYKNFVKSTATNKVRTYITKTYCLRYVGGIVDYHSLDTTDEFKKAVEALPDKFDSHSCTI 747

Query: 190 ATYLAE--------------LLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT 235
            T+ +                 I  +GTH  T V  G  +  +  +  S +L  Q +   
Sbjct: 748 ETFKSNEDDSICAETVLPWMQFIKMFGTHFTTIVHLGGKITHQVQIDKSDVLHMQQNGIN 807

Query: 236 VTASAGIAFLNIV--NFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGIT---LE 290
           V A+   +   ++  + +      S+ +      + + + +V   GG           L 
Sbjct: 808 VDAAVKASISPVMVDSLQGGFASTSEKASLSQSNNLKYDKQVLVIGGDGLVDSKNANSLN 867

Query: 291 TWQKGITNHLVAIDRAGLPLHFFI 314
            W K +    + I      +   +
Sbjct: 868 NWAKELYKRPMPIKIKLESIKSLL 891


>UniRef50_UPI00016E2000 UPI00016E2000 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E2000
          Length = 588

 Score =  119 bits (299), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 71/450 (15%), Positives = 137/450 (30%), Gaps = 65/450 (14%)

Query: 32  QICKNALKLPVLEVLPGGGWDNLRNVDMGRVM---------DLTYTNCKTTEDGQYIIPD 82
           + C +A   P    L G G+D  +    G  +         D T T C            
Sbjct: 30  KECLDAEFAPG-SNLAGEGFDITKLERKGAFVIDMNQWKHKDRTCTLCSNPYLENKKQKL 88

Query: 83  EVYTI---PQKESNLEMNSEVLESW------------MNYQSTTSLSINTELALFSRVNG 127
            V  +    +    +++ S++  S              N+Q+   +    + A    + G
Sbjct: 89  PVSVVDWRSKASCTMQITSKLHRSSESLVTSSSSSVDNNWQTNLDIQKGNKAASM-MLAG 147

Query: 128 KFSTEFQRMKTLQVKDQAVTTRVQVRNRIY-TVKTTPTSELSLGFTKALMDICDQLEKNQ 186
             S   +        D+   T   +    Y +++ + + +LS  F +A+  +       +
Sbjct: 148 THSKLAEYSMEKTKNDKFSFTSQGMSCTFYRSLRVSDSPKLSNEFLRAVRGLPKTY-SPE 206

Query: 187 TKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSS--FLLDNQNSQNTVTASAGIAF 244
            K   Y    LI N+GTH IT V  G +      +R     L      +  +   A  + 
Sbjct: 207 YKARFY---KLIDNFGTHYITKVRLGGSAHSVTSIRQCQASLQGLSTEEVQMCLEAEASA 263

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRT----NSRVQSFGGVPFYPGITLE---------T 291
                 K E  +  + +   ++ ++ +    +   +  GG    P +             
Sbjct: 264 TVKATMKSEMKHCKKDTEKMEFKTSFSGLFNDRFTEIKGGQTTEPDLLFSADKNPAAYKE 323

Query: 292 WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYY-TFNTHPGC 350
           W   +  +   +  +   LH  ++ D              K + +A+ HY         C
Sbjct: 324 WLNTLPLNPDIVSYSLNSLHELLQVD----------HPARKNLRSAISHYILERGLWKNC 373

Query: 351 TNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQEC--TELSGDVLCQNLEQKNLLTGDF- 407
           +          +    D C  +  N     V QEC  T      +   +E+ + L GD  
Sbjct: 374 SEPCRAGVKSDSR---DPCVCQCHNDP--AVNQECCPTRKGMARVIITVERGSGLWGDHT 428

Query: 408 SCPPGYSPVHLLSQTHEEGYSRLECKKKCT 437
           +   GY  V   +   +             
Sbjct: 429 TATDGYVKVFFNNVMFQRTRVIYNNNDPHW 458


>UniRef50_A1E348 Perforin-like protein 1 n=4 Tax=Toxoplasma gondii
           RepID=A1E348_TOXGO
          Length = 1150

 Score =  117 bits (293), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 48/349 (13%), Positives = 100/349 (28%), Gaps = 53/349 (15%)

Query: 35  KNALKLPVLEVLPGGGWDNLRNVDMG------------RVMDLTYTNCK--TTEDGQYII 80
           K    +P +  L G G+D++R   +G             V+  TY   +   + D   + 
Sbjct: 458 KATKTVPAINYL-GAGYDHVRGNPVGDPSSMGDPGIRPPVLRFTYAQNEDGVSNDLTVLQ 516

Query: 81  PDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL-FSRVNGKFSTEFQRMKTL 139
           P   Y               L +  +YQ+  S+  + +        +   ST ++     
Sbjct: 517 PLGGYVRQYVACRQSETISELSNLSDYQNELSVDASLQGGDPIGLNSFSASTGYRDFAKE 576

Query: 140 QVKDQAVTTRVQVRNRIYTVKTTPT----SELSLGFTKALMDICDQLE------------ 183
             K    T  ++     Y      +      ++L F   +  + D  +            
Sbjct: 577 VSKKDTRTYMLKNYCMRYEAGVAQSNHFKWNVTLAFAAGVSQLPDVFDAHNPECACSAEQ 636

Query: 184 -------KNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTV 236
                  +  TK    +    I  +GTH +  + AG  +  +   + S +   +N    V
Sbjct: 637 WRQDQNAEACTKTNVPIWISFIEQFGTHFLVRLFAGGKMTYQVTAKRSEVEKMRNMGIDV 696

Query: 237 TASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGIT--LETWQK 294
                +    +     +     +   + +Y  N     +   G  P        L  W  
Sbjct: 697 KTQLKMQLGGVSGGAGQGTSSKKNQSSSEYQMNVQKETLVIGGRPPGNVSDPAALAAWAD 756

Query: 295 GITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYT 343
            +    + +     PL+  +  +              +  + AV  Y  
Sbjct: 757 TVEELPMPVKFEVQPLYHLLPVE------------KQEAFKQAVTFYSK 793


>UniRef50_A7RF41 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RF41_NEMVE
          Length = 1175

 Score =  117 bits (293), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 46/302 (15%), Positives = 97/302 (32%), Gaps = 33/302 (10%)

Query: 46  LPGGGWDNLRNVDMGRVMDLTYTN---CKTTEDGQY--IIPDEVYTIPQKESNLEMNSEV 100
            PGG    + N  +       Y+    C +  + +    +PD +      +++  M +  
Sbjct: 146 YPGG---FIGNAILNGCFGTNYSQGDPCYSPAETKTQCRVPDTMNVHGIYDTSASMFT-- 200

Query: 101 LESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVK 160
             S   YQS          + F    G          T +    +V      R  I+  +
Sbjct: 201 FSSRSEYQSFLQREAGVSGSYFGFYAGVTKAWGSSTSTNKQMFLSVFDIGVSRYEIFKDE 260

Query: 161 TTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDH 220
             P  +LS  F K  +++       +   A    +  I+ +GTH I S   G  L     
Sbjct: 261 VKPQ-DLSQAFLKEFINLPPSYYTPR---APIAYQDFIMRWGTHYIKSATFGGQL----E 312

Query: 221 VRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG 280
           +R      +  ++  V     + + ++  +     Y S+   ++   +  +++ +++ GG
Sbjct: 313 LRKLMQGSSTATKTEVAEEMEVEYKSLF-WSAGAKYGSRKGTSQRSETKTSSTSLEAQGG 371

Query: 281 ---------VPFYPGI--TLETWQKGITNHLVAIDRAGLPLHFFIK---PDKLPGLPGPL 326
                      + P      ++W + I +   A       +   +     D  P      
Sbjct: 372 SQEIAAILSDMYSPTFKGEFKSWLQSIPDFPKAFKFQMGSVADLVNFRYSDLFPDDEKSD 431

Query: 327 VK 328
            K
Sbjct: 432 KK 433


>UniRef50_Q4Y6N1 Putative uncharacterized protein n=2 Tax=Plasmodium (Vinckeia)
           RepID=Q4Y6N1_PLACH
          Length = 990

 Score =  117 bits (292), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 84/588 (14%), Positives = 171/588 (29%), Gaps = 93/588 (15%)

Query: 20  DKPLGET---GTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDG 76
             P G+       GF+     + +    +      DN+   +  +       N K + + 
Sbjct: 376 GNPEGDPLLNVDPGFRAPVIQINITDTGINNNN--DNVEEHEDSQDSHSNTGNIKHSSNK 433

Query: 77  QYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRM 136
           + IIP   + IP+   N   N E ++S   Y       +          +   S  ++  
Sbjct: 434 KKIIP---WIIPEHSCNQSKNVEEIKSLEEYTLELLSDVKVSTPSIFPYSFSASAGYKNA 490

Query: 137 KTLQVKDQAVTTRVQVRNRIY---TVKTTPTSELSLGFTKALMDICDQL----EKNQTKM 189
                   ++   +++    Y      TT T E +  F  AL  + +      E N+   
Sbjct: 491 LKKLKIQNSIIFMMKIYCLRYYTGISTTTNTWEFTNNFRNALNKLPNTFDGLKEDNECTY 550

Query: 190 ATYL--------------AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT 235
             Y+                     +GTHV   +  G  ++ + ++        + +   
Sbjct: 551 EYYITKSHSPQCEKNVNKWMTFFKLHGTHVAHEMYLGGKIIIKVNIEKEEYNKMKETNLD 610

Query: 236 VTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGIT----LET 291
           +       + + +          +    + +++    S+  S  G      I      E 
Sbjct: 611 MKTVFDF-YFHKMGLSA-----RKNRRIQKFINKMHGSKTVSILGGHPGLNIDDPSFFEK 664

Query: 292 WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLV-------------KKLSKTVETAV 338
           W   I  + + I    LP  FF+    +       +             ++    VE  +
Sbjct: 665 WINSIDKNSMPIRTKLLPFSFFMDDPNMIKAYNDALMFYGLTYGIQIFDQQQYNNVEIPI 724

Query: 339 RHYYTFNTHPGCTNVDSPNF-----------NFQANMD-------------------DDS 368
             Y   N+     +   P              F  N+D                    +S
Sbjct: 725 GDYLE-NSIQQIYHGSPPGLLTCPIGTTILMGFSLNLDFYKNQSLNEIIGINPCEQLKES 783

Query: 369 CDAK--VTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYS---PVHLLSQTH 423
           C     +  ++   ++  C+E +   + Q +EQ        +CP  Y       L+    
Sbjct: 784 CSGNGFINKYSDIRIWGLCSEKTLYFIKQVVEQNETTKTTATCPGNYVILFGFALMKGIG 843

Query: 424 EEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDK 483
               + ++     T +  C  + ++        + A  CV    +   S   F  V    
Sbjct: 844 RSSANAVDLYPCRTGQNSCSAILQNQKFKQSMIYIA--CVDKATIGLESLQTFTKVKNLG 901

Query: 484 TINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSC 531
           +++   N Q+   GY+ L   E+  +      E    F      F  C
Sbjct: 902 SVDS-NNYQN--DGYLDLECPENSTLVFGFAMEFHTNFQKARDNFIKC 946


>UniRef50_Q6DBQ7 Complement component 8, alpha polypeptide n=10 Tax=Clupeocephala
           RepID=Q6DBQ7_DANRE
          Length = 478

 Score =  116 bits (290), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 70/462 (15%), Positives = 138/462 (29%), Gaps = 84/462 (18%)

Query: 25  ETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTY--TNCKTTEDGQ----- 77
           E    G   C+  L +P        G++ L    + RV+D  Y    C+   +G+     
Sbjct: 33  EAINRGENKCEGMLIIPG-ADKATLGYNALTGSFVSRVLDPNYVGGVCEYIYNGEWRKLT 91

Query: 78  ----------------YIIPDE-VYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA 120
                           Y  P   +      +++ E +S+  E  +++        +    
Sbjct: 92  FDPFCEHLSYDDAEKYYRKPYNFLSFQIMAQASTEESSDYYEDAVSFLRAKHSENSFNFG 151

Query: 121 L-----FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTP---TSELSLGFT 172
           +     F     +FS EF  +  +          VQ+ ++I T +         L     
Sbjct: 152 IKPQIGFVEFGVEFSAEFMFLNNISKYTNKEMGFVQLMSKIQTSQFKMRSKDLVLDEDML 211

Query: 173 KALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNS 232
            AL D+ D                    YGTH +T    G  +     V  + + +NQ +
Sbjct: 212 WALSDLPDHYHFGAYSQ-------FFNEYGTHYVTEGTMGGLMDYVAVVNINEMEENQMT 264

Query: 233 QNTVTASAGIAFLNIVNFKVETDYISQTS---LTKDYLSNRTNSRVQ------------- 276
              + +  G +F  +   K++     ++     + +  S+ ++S ++             
Sbjct: 265 GQMIGSCIGGSFGLVFMEKIKATVKGKSCGKFTSNEKTSDESHSAIKDVFGFVKGGNTAS 324

Query: 277 SFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVET 336
           S G +      + + W K +  +   I+   LP++  ++           +      V+ 
Sbjct: 325 SAGSLGIKDAKSYKDWGKSLKYNPALIEFEILPIYELLRLSTAAEQLSSKLP----HVKM 380

Query: 337 AVRHYY-TFNTHPGCTNVDSPNFNFQANMDDDS-CDAKVTNFTFGGVYQECTELSGDVLC 394
           A   Y   FN         +P  N    +   + C     N   G   +E          
Sbjct: 381 AWEEYMQNFNPCR-----CAPCLNNGVPVLSGTACSCLCKNGYTGAACEETERKG----- 430

Query: 395 QNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKC 436
                     G +SC   +S      +T         C    
Sbjct: 431 -------PTDGVWSCWSTWSSCLFGKKTRSRD-----CNNPS 460


>UniRef50_A7AUQ4 Mac/perforin domain containing protein n=1 Tax=Babesia bovis
           RepID=A7AUQ4_BABBO
          Length = 752

 Score =  114 bits (284), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 47/326 (14%), Positives = 95/326 (29%), Gaps = 41/326 (12%)

Query: 48  GGGWDNLRNVDMG---RVMDLTY-----------TNCKTTEDGQYIIPDEVYTIPQKES- 92
           G G+D L+   MG    ++D  Y                +    +I P   +  P     
Sbjct: 426 GAGYDLLKGNPMGDTIILLDPGYRASVVQMHWRDDAEGLSNSRHFIQPKGAWVRPYTSCH 485

Query: 93  NLEMNSEVLESWMNYQSTTSLSINTELALFS-RVNGKFSTEFQRMKTLQVKDQAVTTRVQ 151
             E  SEV ++  +  +  S   +   +L   +     S  +  +K         T   +
Sbjct: 486 KGETISEVAKT-QSLDNVLSADASVSASLPGDKFKFAASVNYNNIKKAYDSKGVNTYVSR 544

Query: 152 VRNRIYTVKTTPT--SELSLGFTKALMDICDQLEK-------------------NQTKMA 190
                +      +   + +  F  AL  +    ++                      ++ 
Sbjct: 545 SYCFNFVAGIPMSIKWDTTQAFQAALKGLPKTFQEEGNGLVCHPYDYLVHPRSQACKELG 604

Query: 191 TYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNF 250
                     +GTHV T V  G  ++     +SS   D +     V A   +    +   
Sbjct: 605 VTAWMQFFTVFGTHVTTKVYLGGKMLTIIETKSSQEADLKKKGIDVKAELSVQ-AEVATV 663

Query: 251 KVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITL--ETWQKGITNHLVAIDRAGL 308
               +  + +   +D  S  T   +   GG  +  G T+    W   +  + + I     
Sbjct: 664 DASVNASTSSLHNRDTESLDTKKSMFVIGGDIYGDGNTIVFNDWAATVPENSMPIKAEYT 723

Query: 309 PLHFFIKPDKLPGLPGPLVKKLSKTV 334
           PL   +  + +       +     +V
Sbjct: 724 PLAMIMGHEYMKAYNDAYLFYGKVSV 749


>UniRef50_B6KDF3 Membrane-attack complex / perforin domain-containing protein n=3
           Tax=Toxoplasma gondii RepID=B6KDF3_TOXGO
          Length = 854

 Score =  112 bits (280), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 40/298 (13%), Positives = 80/298 (26%), Gaps = 42/298 (14%)

Query: 48  GGGWDNLRNVDMG--------------RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESN 93
           G G+D+++   +G               V          T D  Y+ P   +T P     
Sbjct: 237 GVGYDSIKGNPIGDPDMMVDPGLRSPIIVFSFQQDPDGVTNDLNYLQPLGAFTRPFSACR 296

Query: 94  LEMNSEVLESWMNYQSTTSLSINT-ELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQV 152
              N   L++  +YQ   S+             +   ST ++            +  ++ 
Sbjct: 297 QSENVNELDTLSDYQKVLSVDAALHGGDSLGINSFSGSTGYKEFAQDVSSKANKSFMLKT 356

Query: 153 RNRIYTVKTTPT----SELSLGFTKALMDICDQLEKNQTKM----ATYLAE--------- 195
               Y      T       +L F  A+  +    + N+         + A+         
Sbjct: 357 YCIRYEAGLAQTDSFKWNYTLAFDDAVAHLPVTFDGNERDTPCSVQQWRADHMADGCQQT 416

Query: 196 ------LLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVN 249
                   I  +GTH    + AG  +  +  ++SS +   +     V A   +      +
Sbjct: 417 NIPIWMAFIEQFGTHYTARLYAGGKMTYQVTMKSSDVKALKKKGVDVKAEVKLMLGG-FS 475

Query: 250 FKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGIT---LETWQKGITNHLVAID 304
               +   +         S          GG P         +  W   +    + + 
Sbjct: 476 AGASSQVKTNQDSASQLRSLNVEKEALVIGGKPPADVSDPKAIAAWANSVDALPMPVK 533


>UniRef50_B3LCG2 MAC/Perforin domain, putative n=4 Tax=Plasmodium RepID=B3LCG2_PLAKH
          Length = 1102

 Score =  110 bits (274), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 79/569 (13%), Positives = 158/569 (27%), Gaps = 103/569 (18%)

Query: 20   DKPLGET---GTTGFQICKNALKLPVLEVLPGGGWD-----NLRNVDM--GRVMDLTYTN 69
              P G+       GF+     + +  + V      D     +L   D+  G +     T 
Sbjct: 477  GNPEGDPTINVDPGFRGPVLQINIEEMRVNKDISGDLNGTTSLYGSDIRGGGLPYRESTL 536

Query: 70   CKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKF 129
                   ++      + IP+   +   N E +++   Y+      +          +   
Sbjct: 537  MGDYTIEEHKTKLTPWVIPEHSCSQSKNVEEIQNLEQYKMELLSDVKVSTPSIFPYSFSA 596

Query: 130  STEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT--SELSLGFTKALMDICDQL----E 183
            S E++           V   +++    Y      T     +  F  AL  +        E
Sbjct: 597  SAEYKNAIKKLKVQNNVIFMMKIYCLRYYTGIPTTTSWRFTDNFRNALKKLPRTFDGLKE 656

Query: 184  KNQTKMATYL--------------AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDN 229
             +Q     Y+                +    +GTHV   +  G  ++ + ++        
Sbjct: 657  DSQCSYEYYINKIHTPECEENVNKWMMFFRLHGTHVAHEIYLGGKIIIKMNMEKDEYNKL 716

Query: 230  QNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGIT- 288
            +++  ++       + + +         +Q    K     RT+  +   GG P       
Sbjct: 717  KDNNISIKTFFN-LYFHKMGLSGGYSKHTQ----KLVKKFRTSEDISILGGNPGLNIENS 771

Query: 289  --LETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK-------------KLSKT 333
               E W   I  + + I    LP  FF+    +       +              +    
Sbjct: 772  TFFEKWVNSINKNSMPIRTKLLPFSFFMDDPYMIQAYKDALTFYGLTYGVQIFDHEKYSH 831

Query: 334  VETAVRHYYTFNTHPGCTNVD---------------------SPNFNFQAN------MDD 366
            V  ++  Y        CT                        S N +F  N         
Sbjct: 832  VVLSIGEYLE-----KCTQKLYAGPPPGLLTCPLGSSLLMGFSLNLDFYKNKDLSSTNGM 886

Query: 367  DSCDAKVTNFTFGG---------VYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYS--- 414
             SC+    + +  G         ++  C+E   D + Q ++Q        SCP       
Sbjct: 887  ASCEQMKESCSGNGFGKKYSDIRIWGLCSEKPLDFITQVVQQGESPKITASCPGNLVILF 946

Query: 415  PVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQV------ 468
               L+        ++++     T +  C  V ++        + A  CV           
Sbjct: 947  GFALMKGKGSSSANKVDIYPCRTGQSSCSAVLQNNKIKQSMIYIA--CVDKSTNGLGNIQ 1004

Query: 469  PDNSGLLFGGVFTDKTINPMTNAQSCPAG 497
              +     G V +DK  N  + + +CP  
Sbjct: 1005 TYSKVKNMGYVNSDKDENDTSLSFACPKN 1033


>UniRef50_UPI0001924DF1 PREDICTED: similar to conserved hypothetical protein n=1 Tax=Hydra
           magnipapillata RepID=UPI0001924DF1
          Length = 684

 Score =  110 bits (274), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 63/402 (15%), Positives = 115/402 (28%), Gaps = 68/402 (16%)

Query: 1   MNSFMALVLI-----WMIIACAEADKPLGETGTTGFQICKNALKL-------PVLEVLPG 48
           M+ F+ L+L        ++  +E+  P+    ++  +               P  E  P 
Sbjct: 26  MHHFLILLLAYPCMCSELVTQSESKPPISN--SSEEKNIVINPTYCNADWCDPSHEPYPN 83

Query: 49  G-----GWDNLRN--------VDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLE 95
                 G++ L+         VD G      +     T DG Y +   +      + +L 
Sbjct: 84  IVSIMTGYNILKGNPFTTTQSVDPGFSTGYIFAPIARTADGTYALDSGITVRQTLQCSLT 143

Query: 96  MNSEVLESWMNYQSTTSLSINTELALFSRV---------------------------NGK 128
            +SE + +  NY        +      S +                           +  
Sbjct: 144 SSSETITTLENYVKKVQSKSSEGGTFTSNLEFEVTGEVEKGGVKGSVSTKIPPLVQSSFS 203

Query: 129 FSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKT--TPTSELSLGFTKALMDICDQLEKNQ 186
            S +++  K    K + V T        Y+V          S  F  AL ++ D +   Q
Sbjct: 204 SSNDYKNNKDFFEKTKGVMTLRDATCATYSVVVSSYKPPPFSDAFKDALKELND-VTNKQ 262

Query: 187 TKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLN 246
            K      +  +  +GTH +     GA               + + Q     S     + 
Sbjct: 263 KKGRKRAFKKFVREFGTHFLEQATMGARTAVTRRYTQKEFRHSTDEQIQ-KCSEQRLLVT 321

Query: 247 IVNFKVETDYISQT----SLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVA 302
           I    V     S      S      +      V S+G     P   L  W K      + 
Sbjct: 322 IAGVGVGKSSESCNNIDMSSNNYNFNGAERESVTSYGS---KPAENLYEWSKQKFESPLP 378

Query: 303 IDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTF 344
           I     P+      + +  LP    K++   ++  +  YY +
Sbjct: 379 IAMKLSPIINLFSKNYMKNLPDIKYKEI---LKYFIPLYYNY 417


>UniRef50_C3ZX08 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZX08_BRAFL
          Length = 1195

 Score =  107 bits (266), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 42/305 (13%), Positives = 91/305 (29%), Gaps = 49/305 (16%)

Query: 80  IPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTL 139
           IPD +      +   +  SE   S  +Y+ +         + +     + S       + 
Sbjct: 234 IPDNMNVHGIYD--TDTKSETFNSRQSYRQSLQQKAGVSASGWG---FQASVNAAWGGSQ 288

Query: 140 QVKDQAVTTRVQVRNRIYTVKTTPTSE--LSLGFTKALMDICDQLEKNQTKMATYLAELL 197
           + + Q   + ++     Y +         LSL F +  + +       + K      +  
Sbjct: 289 KSEKQVFMSLIEADVIRYEIFLDEVKPDDLSLDFLRDFLSLPKNFILGKAK-----LQDF 343

Query: 198 ILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYI 257
           I+ YGTH I S   G A      +  +   ++  S ++ + SA  ++  + +        
Sbjct: 344 IIRYGTHFIKSAKFGGAF----RLFKTQEAESGESLSSFSVSAQASYNGMFSAGGHYGRK 399

Query: 258 SQTSLTKDYLSNRTNSRVQ-------SFGGVPFYPGI--TLETWQKGITNHLVAIDRAGL 308
            ++       ++ T+  ++       +     +  G   T + W K I ++   ID    
Sbjct: 400 EESGAKSSEKTSSTHVVIEGGDQKVGAIVADFYTTGFKDTFQEWLKSIPSYPKPIDMFMG 459

Query: 309 PLHFFIK---PDKLP---------------------GLPGPLVKKLSKTVETAVRHYYTF 344
            L   +        P                           + K    +E A+  Y   
Sbjct: 460 TLSELLNLNFKTLFPFDMSDAADGCFSKKYCDDSSIEEFQLSMDKKRLALERAISVYMEE 519

Query: 345 NTHPG 349
              P 
Sbjct: 520 GPIPT 524


>UniRef50_Q4UDM0 Hypothetical membrane protein, conserved n=2 Tax=Theileria
           RepID=Q4UDM0_THEAN
          Length = 817

 Score =  106 bits (265), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 71/471 (15%), Positives = 137/471 (29%), Gaps = 66/471 (14%)

Query: 35  KNALKLPVLEVLPGGGWDNLRNVDMG---RVMDLTYTNC-----------KTTEDGQYII 80
           K       LE L G G+D ++   +G    ++D  Y +              +   +++ 
Sbjct: 339 KRFKTPSGLEYL-GAGYDLIKGNPLGDSVTLLDPGYKSSVIQMHWSKNIENISNSLRFLQ 397

Query: 81  PDEVYTIPQKES-NLEMNSEVLESWMNYQSTTSLSINTELALFSR-VNGKFSTEFQRMKT 138
           P   +  P      +E  +E ++S  +   + S   +  L+L         S +F++++ 
Sbjct: 398 PIGGWIRPYSSCHKVETVTE-IKSSKSLLKSLSADASVSLSLPGDDFKFSASAKFKKLED 456

Query: 139 LQVKDQAVTTRVQVRNRIYTVKTTP--TSELSLGFTKALMDICDQLE------------- 183
                 +     +     Y    +     +L+LGF  +L  +  + +             
Sbjct: 457 ASKSRNSKVYINKSYCFKYVAGISTSLNWDLTLGFQSSLKRLSTEFKGFEKNSMCRPYIY 516

Query: 184 ------KNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVT 237
                 +N  ++       L   +GTHV T +  G  +     V+ +      +    V 
Sbjct: 517 REDPKNENCEELGVSDWMELFNTFGTHVATKIYLGGKIFTTLEVKKNQEKKLSDQGLDVK 576

Query: 238 ASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPF--YPGITLETWQKG 295
           A       + +      +  +  S         T       GG  +     I    W + 
Sbjct: 577 AILSAKIKD-IGIDSNVEVSTIKSKNSLDHLLDTKKSTFVLGGDIYGHGKTIEFGEWARS 635

Query: 296 ITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDS 355
           + +H + I     P+  FI             KKLS+T   A  +Y            +S
Sbjct: 636 VADHSMPIKAEFTPISHFID------------KKLSETYNKAYLYYADVVLESDFLRYES 683

Query: 356 -PNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLT--------GD 406
                 +  +DD   +    N   G V   C +         +      T          
Sbjct: 684 QVELTPEELIDDVEIE---HNQGSGDVKVSCKDGKSIQFGFMILSLKDNTYEVRECPIHA 740

Query: 407 FSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEF 457
             C  G       S        +     +  L    K  CE+ F +    +
Sbjct: 741 TECSSGSDEKIGYSSLWIACRVQNIVNLRQILTTDKKPSCENGFHIFLGSY 791


>UniRef50_Q4U9X5 MAC/perforin, putative n=2 Tax=Theileria RepID=Q4U9X5_THEAN
          Length = 514

 Score =  106 bits (264), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 55/386 (14%), Positives = 109/386 (28%), Gaps = 67/386 (17%)

Query: 10  IWMIIACAEADK---------PLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMG 60
           I+ +I   +  +          L E  +  F+  K  + L  L    G G+D ++   MG
Sbjct: 34  IYSLIEKNDGGERGRQKTGVDVLQENDSINFKTTKIVVGLEYL----GAGYDIIKANTMG 89

Query: 61  RV--------------MDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMN 106
                                T+   T     + P   +  P+       N   +ES  N
Sbjct: 90  DSEQGEDLGYRAPVIDFAWAQTDVGVTNSLDSLQPVGGWVRPKVSCGESENVTEIESISN 149

Query: 107 YQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTP--T 164
            +  T   +  ++ + +   G  +T++Q +K      +            Y     P   
Sbjct: 150 LKDVTESDVQVDVKVPNVGTGSLNTQYQELKADSENRKNKLYTNTYYCFTYAAGIPPTLD 209

Query: 165 SELSLGFTKALMDICDQLEKNQTKMATYL------------AELLILNYGTHVITSVD-- 210
              +  F  ++ ++  +++  +                          +GTHV+  V   
Sbjct: 210 WNTTEDFNLSVSELPKKIKDYEKCTPEGYKKRIKECKDLVKWMEFFSEFGTHVVVQVHLG 269

Query: 211 --------AGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSL 262
                    G  L +   V SS +    N    V A  G      V   +          
Sbjct: 270 EQRINQYILGGKLTRYLSVPSSIIESLSNKGFDVNAVIGAVISG-VKTDISVGASKSDES 328

Query: 263 TKDYLSNRTNSRVQSFGGVPFYPGI---TLETWQKGITNHLVAIDRAGLPLHFFIKPDKL 319
               L   +  +    GG+     I   ++  W+  +  + + I      +  F+     
Sbjct: 329 EIKQLKKSSKLKFSVLGGIHPDRQISPSSIRNWKSTVPRYPMPIKIDVETISTFLPRSYY 388

Query: 320 PGLPGPLVKKLSKTVETAVRHYYTFN 345
                        + + A+  Y T N
Sbjct: 389 ------------NSFKEALNFYITLN 402


>UniRef50_C0YM92 Putative uncharacterized protein n=1 Tax=Chryseobacterium gleum
           ATCC 35910 RepID=C0YM92_9FLAO
          Length = 460

 Score =  105 bits (261), Expect = 8e-21,   Method: Composition-based stats.
 Identities = 48/296 (16%), Positives = 89/296 (30%), Gaps = 63/296 (21%)

Query: 79  IIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA---LFSRVNGKFSTEFQR 135
           +I +  ++        E   E  E+  +Y    S  +N           ++  F++    
Sbjct: 88  LISENTFSQ-------EYTEEYGENAESYSKMVSTKVNATAGIPLFKKTLSVGFNSAVTT 140

Query: 136 MKTLQVKD--QAVTTRVQVRNRIYTVKTTPTSE-LSLGFTKALMDICDQLEKNQTKMATY 192
               + K    +    ++ +   +   T    + L+  F + L                 
Sbjct: 141 NNKFEGKYIYGSYNLTIKQKRVRFNATTDMLGDYLTPEFAQDLQTKT------------- 187

Query: 193 LAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKV 252
             + ++ +YGTHV   +  GA L   D +  +        +    A  G+       F V
Sbjct: 188 -PQQIVQDYGTHVAVDIYTGAKL---DVLFQAETRSQSRDR---AARIGVKVGMKDIFDV 240

Query: 253 ETDYISQTSLTK-DYLSNRTNSRVQSFGGVPFY------------PGITLETWQKGITNH 299
           +      TS +  +Y          + GG P              P I +  WQ      
Sbjct: 241 DVTNDVNTSESSMNYSKKLAYK---TRGGDPSKGLVGDLNLDQTNPKINISNWQNSSNAS 297

Query: 300 ---LVAIDRAGLP-LHFFIKPDKLPGLPGPLVKKLSKTVETAV---RHYYTFNTHP 348
              LV     GL  ++  +K             +L   V+  +   + Y  FNT P
Sbjct: 298 NSVLVDFGSNGLVIIYDLVKD-------AAKKAQLKAYVDQYLIDNKVYMEFNTIP 346


>UniRef50_C3YX95 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
           RepID=C3YX95_BRAFL
          Length = 722

 Score =  104 bits (260), Expect = 8e-21,   Method: Composition-based stats.
 Identities = 72/456 (15%), Positives = 133/456 (29%), Gaps = 67/456 (14%)

Query: 20  DKPLGETGTTGFQICKNALKLPVLE---VLPGGGWDNLRNVDMGRVMDLT-YT-NCKTTE 74
                E      Q       +  L     + G G++ L     G V+D + Y   C+T  
Sbjct: 184 GDQSDEQECPDVQNLCEGKTVEGLIPNIDIAGSGYNVLTEELSGLVLDNSKYGGQCRTAY 243

Query: 75  DGQ----YIIPDEVYTIP-QKESNLEMNSEVLESWMN-YQSTTS-------LSINTELAL 121
            G     + +P        Q  ++    +E   S    YQ TT+          + E ++
Sbjct: 244 SGDHGKTFRLPHNTQFYRFQVVADTSFRAEQFSSSKQFYQDTTANKQRDIHAGASAEFSV 303

Query: 122 FSRVNGKFSTEF----QRMKTLQVKDQAVTTRV-QVRNRIYTVKTTPTSELSLGFTKALM 176
           FS      S++       +K+ Q  D A+ T   Q+    + +       L+  F +AL 
Sbjct: 304 FSASGEVASSQSHGNHDVIKSSQSSDSALFTVSNQIELAQFRMNGDNNFILTDSFYRALE 363

Query: 177 DICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTV 236
           ++       +        + LI+++GTH +++   G             L ++  S    
Sbjct: 364 ELPVVYSYAE-------YKKLIVDFGTHYVSAGRLGGQYRYAYRYNRRNLTESGLSDEQQ 416

Query: 237 TASAGIAFLNIV---NFKVETDYISQTSLTKDYLSNRTN----SRVQSFGGVPFYPG--- 286
            +   +                      L++    + T     S     GG     G   
Sbjct: 417 KSCLSVEAKASFLGIGISGGYKNCQDNRLSQQTAGSFTLAARDSVSFVKGGTSETAGSLA 476

Query: 287 -------ITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVR 339
                     + W   + N+   I     PL   +    L  +         + +  A+ 
Sbjct: 477 YTNQPMTDKYQAWLDDVKNNPAVISVELYPLSELVAGVSLAPV-------KKRHLARALV 529

Query: 340 HYYTFNTHPGCTNVDSPNFNFQANMDDDS-CDAKVTNFTFGGVYQECTELSGDVLCQNLE 398
            Y     HP C    +P  N    +   + C+      T+G   +         +     
Sbjct: 530 QYLDE-FHP-C--KCAPCRNNGKAVLIGTACECVCAEGTYGASCET--------VADPSL 577

Query: 399 QKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKK 434
               + G +SC  G+S           G  R     
Sbjct: 578 AVKDVDGSWSCWTGWSACTSRCGGGSSGRKRACDNP 613


>UniRef50_Q498V9 LOC570832 protein (Fragment) n=9 Tax=Clupeocephala
           RepID=Q498V9_DANRE
          Length = 829

 Score =  103 bits (257), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 56/376 (14%), Positives = 103/376 (27%), Gaps = 56/376 (14%)

Query: 36  NALKLPVLEVLPGGGWDNLRN-VDMGRVMDLTYT-NCKTTEDGQ----YIIPDEVYTIP- 88
           +  K P    L G G+D L   +  G +   ++   C+    G     Y +P  +     
Sbjct: 131 DKQKPPPNSDLTGRGFDELTGELRAGVINTRSFGGQCRKVFSGDHREFYRLPQNLLRYSF 190

Query: 89  QKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAV-- 146
           Q     +   +  +S  +Y                        + +       +D+    
Sbjct: 191 QVSVENDFTDDYYDSSWSYMRDEKQRRIIRGG----------HDHKTFHNQLKQDKTYHL 240

Query: 147 -TTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHV 205
              R +V    +         LS  F K L  +    E +          L I  YGTH 
Sbjct: 241 LIIRNEVEVAQFQNNAPEYLPLSEDFWKDLSALPITYEPSA-------YRLFIQRYGTHY 293

Query: 206 ITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKD 265
           +     G        + ++++++   ++             +   K  T  +      ++
Sbjct: 294 MEEGSLGGQYRALLELDANYMMEMSRTETDFHQCITRVKRRLFYKKKTTKCVKLMKTIEN 353

Query: 266 YLSNRTNS---RVQSFGG--------------VPFYPGITLETWQKGITNHLVAIDRAGL 308
           +  NR +    +    GG               P         W   +      I +   
Sbjct: 354 FSENRNHKMPIKTDIIGGNSAYIAGLSLLDLENPDNNKQMYTKWAGSVKEFPKVIKQKLR 413

Query: 309 PLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQ-ANMDDD 367
           PLH  +K     GL           ++ A+  Y    +   C     P  N   A + + 
Sbjct: 414 PLHELVKEVACAGL-------KKVHLKRALEAYLEEQSPCHC----RPCQNNGMAVLSEG 462

Query: 368 SCDAKVTNFTFGGVYQ 383
            C       T G   Q
Sbjct: 463 VCTCVCRPGTSGNACQ 478


>UniRef50_UPI00006A16E2 Perforin 1 precursor (P1) (Lymphocyte pore forming protein) (PFP)
           (Cytolysin). n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI00006A16E2
          Length = 304

 Score =  103 bits (256), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 38/280 (13%), Positives = 86/280 (30%), Gaps = 41/280 (14%)

Query: 92  SNLEMNSEVLESWMNYQSTTSLSINTELALFSR----------VNGKFSTEFQRMKTLQV 141
              E+ S+ L S ++     +  +  +  + +           + G  S   +       
Sbjct: 39  CKTEIESKTLRSTVSMAKEAASIVQNKWDMMNLTSATTQGSLLLAGSHSKITEFALEKCH 98

Query: 142 KDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNY 201
            D+    + Q+   +Y+ + +   E+S  F +AL  +      N TK++ +    LI  Y
Sbjct: 99  FDKYTFIKHQLECELYSFQLSKDYEVSHHFMEALEQLPGDYNAN-TKVSYF---NLISTY 154

Query: 202 GTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTS 261
           GTH I+    G    +   VR+  +  +  +               V+        S+  
Sbjct: 155 GTHFISKATIGGRAQEIAAVRTCEVALSGMTMEQTKGCLDEEVATAVHNMGSPSLGSKEC 214

Query: 262 L--------TKDYLSNRTNSRVQSFGGVPFYPGITLET---------WQKGITNHLVAID 304
                     +++    +    Q  GG   +  + +           W          + 
Sbjct: 215 ADLAVKYNFIRNFHQAFSERIWQVTGGNSTFNLLDINAGANQDAATRWINSTERFPDLLR 274

Query: 305 RAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTF 344
            + +P+   +  +  P             ++ A+R Y   
Sbjct: 275 YSLIPIDALLDSES-PE---------KYNLKMAIRDYIKE 304


>UniRef50_UPI000180CB36 PREDICTED: similar to complement component C6 n=3 Tax=Ciona
           intestinalis RepID=UPI000180CB36
          Length = 566

 Score =  103 bits (256), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 65/382 (17%), Positives = 109/382 (28%), Gaps = 67/382 (17%)

Query: 48  GGGWDNLRNVDMGRVM-DLTYT-NCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWM 105
           G G+D     ++G ++ +  Y   C     G++   +E +  P    +    S+   S+ 
Sbjct: 207 GLGYDITLGEEIGTILDNRQYAGRCDRVRSGEH---EETFRKPANMQSFRFQSQATSSFT 263

Query: 106 --NYQST----TSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTV 159
             +YQS+     S   N E  L +  +  FS  F    +      + T R+  R     V
Sbjct: 264 AISYQSSKGFYESERSNMERKLQASASFSFSDMFGLSGSATKTRNSKTLRIIDRGTSSDV 323

Query: 160 KT---------------TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTH 204
           K                  + +LS  F + L+++    +  +          LI +YGTH
Sbjct: 324 KYFRVFGEITLSRFRTIRRSFKLSHSFRQRLLELPQHYDYAKYSE-------LIADYGTH 376

Query: 205 VITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIA-----FLNIVNFKVETDYISQ 259
             +S   G           S L  +  +                          T+  S 
Sbjct: 377 FYSSGVLGGRYEYIYRFSKSDLALSGLTDEEQKNCLTTETSMKFLKGFFGGSGGTNKCST 436

Query: 260 TSLTKDYLSNRT----NSRVQSFGG--------VPFYPGIT----LETWQKGITNHLVAI 303
             L++ Y  +       +     GG          +          E W + +      I
Sbjct: 437 NVLSRRYNGSFALAAKEAISNVIGGQSHTTSALTFYSSNGPNTAAYERWSRSVRVSPAII 496

Query: 304 DRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQAN 363
           D    P+   I                   +E A+  YY       CT     N      
Sbjct: 497 DFMLTPMSSVIPDRN-----------KQANMERALYDYYAKYNANKCTGR-CENGGRAVV 544

Query: 364 MDDDS-CDAKVTNFTFGGVYQE 384
           + D S C    T    G   Q 
Sbjct: 545 VKDGSECKCLCTPGHSGPSCQS 566


>UniRef50_UPI0000E46B2F PREDICTED: similar to apextrin, partial n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E46B2F
          Length = 348

 Score =  101 bits (252), Expect = 9e-20,   Method: Composition-based stats.
 Identities = 46/321 (14%), Positives = 92/321 (28%), Gaps = 46/321 (14%)

Query: 40  LPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSE 99
             +LE  P  G D++  +D G +   T+     T D      +EV+   +          
Sbjct: 45  YNILEGNPE-GEDSIGGLDPGLLT--THHVIDLTYDPGNPEANEVHYAERSGDLETSWKT 101

Query: 100 VLESWMNYQSTTSLSINTELALFSRVN---GKFSTEFQRMKTLQVKDQAVTTRVQVRNRI 156
                 +Y       +     + + ++      ST + R+K     +++V          
Sbjct: 102 TYYGTSSYAKKLDHYVEVTGEMNTELSSSRFGASTGYNRVKQKTETEESVFFDRTTVRNR 161

Query: 157 YTVKTT------PTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVD 210
            +++            L  GF      +      N    + Y+    I  +GTHV+T V+
Sbjct: 162 GSLRLKTALARADQFRLDRGFVTTACSLP-----NTWDESDYM--TFIDTWGTHVVTYVE 214

Query: 211 AGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNR 270
            G     +     S  +   +     + SAG  +    +  +  D     S   +     
Sbjct: 215 VGILESFKRKEERSSFVTYASKNFASSVSAGGEYNG-YSASLAVDMEKFNSDEVEEDEFG 273

Query: 271 TNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKL 330
           ++    + G        TL             I      +H   + +        +   L
Sbjct: 274 SSETSYTIGSE------TLNE----------PIKIRLKSMHEIFEDEFWTRSAEYITDDL 317

Query: 331 SKT----------VETAVRHY 341
                        V  A+ +Y
Sbjct: 318 CSNSWRRSVVQGLVLNAIENY 338


>UniRef50_UPI0000521199 PREDICTED: similar to complement component C6 n=3 Tax=Ciona
           intestinalis RepID=UPI0000521199
          Length = 569

 Score =  101 bits (251), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 66/371 (17%), Positives = 116/371 (31%), Gaps = 62/371 (16%)

Query: 46  LPGGGWDNLRNVDMGRVMDLTYTNCK----TTEDGQ--YIIPDEV-YTIPQKESNLEMNS 98
           L G G+D       G+++D    N +     + D    Y  P  + Y   Q   +    +
Sbjct: 212 LAGAGYDITTGKMAGKILDNHQYNGRCVKVVSGDHNQIYRQPANIQYYRFQVSVDSTFTT 271

Query: 99  EVLESWMNY----QSTTSLSINTELAL---------FSRVNGKFSTEFQRMKTLQVKDQA 145
           +   S  +Y    +   S  ++  ++           S   G  ST+    +      Q 
Sbjct: 272 KAYSSAKDYVEDQRKAMSTKVSASVSYGTAFFSASVSSSYTGSKSTKQVVQQASNNDAQF 331

Query: 146 VTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHV 205
            T   +++   +         LS  F + L D+             YL   +I +YGTH 
Sbjct: 332 FTVTSEIKLAQFR-TVRGNYILSHNFRRRLRDLPSHY-----DFMKYL--QVIADYGTHF 383

Query: 206 ITSVDAGAALVQEDHVRSSFLLDNQNSQNT----VTASAGIAFLNIVNFKVETDYISQTS 261
            +S   G           + L  +  S++     ++  A   ++  V+    T   S  S
Sbjct: 384 YSSGVLGGKYDYTYRYSKNELRSSGLSESDQKHCLSLEASARYMG-VSASASTSGCSSNS 442

Query: 262 LTKDYLSNRTNSRVQSF-----GGVPFYPGITLET---------WQKGITNHLVAIDRAG 307
           L+K + S+ T S  +       G       +T            W K +  +   ID   
Sbjct: 443 LSKKHGSSFTKSASEVISKVVGGSSSAAASLTFGKNPDSSKYDAWVKTVKANPTMIDFQL 502

Query: 308 LPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY---YTFNTHPG-CTNVDSPNFNFQAN 363
            P+   I                 + ++ A+ HY   Y +NT  G C N           
Sbjct: 503 TPISAVIPDSA-----------KRRNMQQALYHYMSKYDYNTCKGTCYNGAGKIITNAGK 551

Query: 364 MDDDSCDAKVT 374
                C +  T
Sbjct: 552 TCTCLCKSPYT 562


>UniRef50_B1NM18 Complement component 8 alpha polypeptide n=1 Tax=Ginglymostoma
           cirratum RepID=B1NM18_GINCI
          Length = 589

 Score =  101 bits (250), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 51/353 (14%), Positives = 106/353 (30%), Gaps = 54/353 (15%)

Query: 103 SWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTT 162
           + M +  +   ++  ++++  +    F      ++ +        + V+VR +I T    
Sbjct: 247 TAMKHTDSFDFAVGVQVSV-VKAAIAFGEYSTFIRNVSRFQGKDVSFVRVRTKIQTAHFK 305

Query: 163 P---TSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQED 219
                  L    T++LM + D       +    +    I +YGTH   S   G       
Sbjct: 306 MRRYNLLLDEDMTQSLMKLPD-------EYNYGMYAKFIADYGTHYYASGTMGGVYEFIL 358

Query: 220 HVRSSFLLDNQNSQNTVTASAGIAF-----LNIVNFKVETDYISQTSLTKDYLSNRTNSR 274
            +    L ++  + +        +         ++              +    +  +  
Sbjct: 359 VLNKKALAESDLTASEAGFCVAGSLGVVVSKGTMDVGGSVKAKGCRRKLEQNEPSEKSRS 418

Query: 275 V------QSFGGVPFYPGITL----------ETWQKGITNHLVAIDRAGLPLHFFIKPDK 318
           +         GG        L            W K +      ID   +P++  +   K
Sbjct: 419 LVEDVLPHVLGGDLKSSAGLLGHGIPDVKMYRHWGKSLKYLPAVIDFELMPIYDLVARSK 478

Query: 319 LPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQ-ANMDDDSCDAKVTNFT 377
           L       V+   + ++ A+  Y     HP C       +N   A + D+ C        
Sbjct: 479 L-----QSVEIKQQNLKRAMEEYL-VEFHP-C--RCPVCYNNGKAVLLDNVCTC------ 523

Query: 378 FGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRL 430
                 EC        CQ+ ++K    G++SC  G+S     S+      +  
Sbjct: 524 ------ECLPGYEGKACQDTKRKGPTNGNWSCWSGWSSCQNGSKQRTRSCNHP 570


>UniRef50_Q9PVW7 Complement component C8 beta chain n=11 Tax=Clupeocephala
           RepID=CO8B_PAROL
          Length = 588

 Score = 99.6 bits (246), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 61/399 (15%), Positives = 118/399 (29%), Gaps = 70/399 (17%)

Query: 33  ICKNALKLPVLEVLPGGGWDNL------RNVDM-GRVMDLTY--TNCKTTE--DGQYIIP 81
            CK   K    E     G +NL       N ++ G V+D  Y   +C      D ++  P
Sbjct: 150 GCKKVPKPCRQEAEEYWGIENLAKGINILNSNLEGLVLDNRYYAGSCLPQYIQDVRFRKP 209

Query: 82  DEV--YTIPQKESNLEMNSEVLESWMNYQSTTSLS------INTELALFSRVNGKFSTEF 133
             +  YT+  K S  + N +  ES+ +Y   +         ++   A+       F+   
Sbjct: 210 HNLQQYTLETKGS-YDFNVQSFESYSDYMDYSMRERMTQTIVSIGFAIPGIAEFGFNYNN 268

Query: 134 QRM--------KTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKN 185
            ++        +     +  V+ + ++    Y ++ +    L   F + L  +       
Sbjct: 269 AKVTRSIQKIRRASSKINSFVSAKAELELAQYMLR-SDDLMLHPEFLQRLRSLPQAYVYG 327

Query: 186 QTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQ------NSQNTVTAS 239
           + +        +  +YGTH IT    G        +    L           S       
Sbjct: 328 EYRQ-------IYRDYGTHYITEAALGGEYEHTIILDKEKLAKTDYSLEDYKSCTQAGLK 380

Query: 240 AGIAFLNIVNFKVETDYISQTSLTKDY-----LSNRTNSRVQSFGGVPFYP--------- 285
            G      V      +  S   L  +      + +     V    G              
Sbjct: 381 IGANIYG-VYVSAGIEGGSCNGLLNEMGEDTAIGSSVEDFVAVVRGGSSESITGLVSKKL 439

Query: 286 --GITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYT 343
                +  W +G+  +   I +   PL+  +               L + ++ A+  Y  
Sbjct: 440 PTPQLMRLWGEGVRFNPDFIRKTTRPLYELVTSKDF-----SHDATLKRNLKRALSEYLA 494

Query: 344 FNTHPGCTNVDSPNFNFQANMDDDS-CDAKV-TNFTFGG 380
            ++   C    +P  N    +   + CD    T +T  G
Sbjct: 495 ESS--SC--RCAPCHNNGVAVLRGTRCDCVCPTGYTGRG 529


>UniRef50_UPI000180B7EE PREDICTED: similar to HyTSR1 protein n=4 Tax=Ciona intestinalis
            RepID=UPI000180B7EE
          Length = 1108

 Score = 98.8 bits (244), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 49/378 (12%), Positives = 108/378 (28%), Gaps = 49/378 (12%)

Query: 33   ICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEV-----YTI 87
              +   K+P + +  G G+D  +  + G +MD    N +    G + IP  +     + +
Sbjct: 745  GSRLFKKIPGINIT-GSGFDITKLREEGIIMDNERYNGRCLTVGGFRIPANMLFYWFHVL 803

Query: 88   PQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKD---- 143
                  ++     +  + + +S+    + +  +    ++ K S+    +KT  V D    
Sbjct: 804  VNPSFIIKSYESSMNYFQDERSSFRQKLGSSSSHTKILSAK-SSGSNSIKTRMVIDFGTD 862

Query: 144  ---QAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILN 200
               +       V    +++       LS  F + L  + +  + ++          +I +
Sbjct: 863  SDSKFFKISNTVEVARFSM-FGQKLLLSFEFQQRLEQLPNNFDYSKYAQ-------VISD 914

Query: 201  YGTHVITSVDAGAALVQEDHVRSSFLLDNQ----NSQNTVTASAGIAFLNI-VNFKVETD 255
            +GTH  +    G             L  +       ++ +   A  +F            
Sbjct: 915  FGTHFYSRGVLGGKYEYVYRYSKKALNQSGLTDFEQKSCLEQEAKASFQGSGFGNSKCLS 974

Query: 256  YISQTSLTKDYLSNRTNSRVQSFGGVP------------FYPGITLETWQKGITNHLVAI 303
                      +    TN      GG                     + W K + ++   I
Sbjct: 975  NTLSQKHKGSFTRAATNFVSNVVGGTSEKAAALSFFSGKTPKKSDYDEWVKTVKHNPAMI 1034

Query: 304  DRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQAN 363
            D    P+   +                   +E A+  Y     +  C    +        
Sbjct: 1035 DYKLTPISSAVPLSS---------YNKRINLERALVLYLKEYDYSKCKGKCAHGAAVVVV 1085

Query: 364  MDDDSCDAKVTNFTFGGV 381
             D   C        +GG+
Sbjct: 1086 NDGKLCKCLCA-ANYGGI 1102


>UniRef50_Q8I5P0 MAC/Perforin, putative n=1 Tax=Plasmodium falciparum 3D7
           RepID=Q8I5P0_PLAF7
          Length = 1073

 Score = 98.4 bits (243), Expect = 8e-19,   Method: Composition-based stats.
 Identities = 57/392 (14%), Positives = 106/392 (27%), Gaps = 89/392 (22%)

Query: 20  DKPLGET---GTTGFQICKNALKLPVLEVLPGGGWDNLRNVD--MGRVMDLTYTNCKTTE 74
             P G+       GF+     + L  + +     +DN +N D  M   +     N   ++
Sbjct: 414 GNPEGDPTLNVDPGFRGPVLQINLKEISLN---SYDNHKNDDNHMNDDIHKNDDNHMNSD 470

Query: 75  DGQ---YIIPDEV--------------------------------------YTIPQKESN 93
           + +   Y   DE                                       + IP+   +
Sbjct: 471 NHKNDEYHKNDEYHKNDEDHNDDNYDNHADGDKRSKERKSKIQTTNESMKPWVIPEHSCS 530

Query: 94  LEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVR 153
              N E + +   Y+      +          +   S EF+           V   +++ 
Sbjct: 531 QSKNVEEIRNLEQYKLELLSDVKVSTPSSFPYSFSASAEFKNALKKLKVQNNVIFLMKIY 590

Query: 154 NRIYTVKTT---PTSELSLGFTKALMDICDQL----EKNQTKMATYL------------- 193
              Y         + + S  F  AL  +        E ++     Y+             
Sbjct: 591 CLRYYTGIPITTTSYKFSENFKNALSKLPKYFDGLREDSKCSYEYYINKLNSPECEENVN 650

Query: 194 -AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKV 252
              L    +GTHV   +  G  ++ + ++        + +   V       F NI   K+
Sbjct: 651 KWMLFFKLHGTHVAYEIYLGGKIIIKININKEEYNKMKENNINVKT-----FFNIYFHKM 705

Query: 253 ETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGIT---LETWQKGITNHLVAIDRAGLP 309
                 Q    K     R +  +   GG P          E W   I  + + I    LP
Sbjct: 706 GLSSAFQKEAQKILNKFRISKHIAILGGNPGLNVNNTSFFEKWVHSINTNSMPIRTKLLP 765

Query: 310 LHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
             FF+               + +  + A+  Y
Sbjct: 766 FSFFMDD-----------NDMIQAYKDALIFY 786


>UniRef50_UPI0001924D14 PREDICTED: similar to apextrin n=4 Tax=Hydra magnipapillata
           RepID=UPI0001924D14
          Length = 657

 Score = 96.9 bits (239), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 66/417 (15%), Positives = 113/417 (27%), Gaps = 70/417 (16%)

Query: 41  PVLEVLPGG-----GWDNLRNV--------DMGRVMDLTYTNCKTTEDGQYIIPDEVYTI 87
           P  E  P       G++ L+          D G      +     T  G Y++   V   
Sbjct: 68  PGHEPYPNIVSIMTGYNILQGNPFTSSHTSDPGFSTGYIFVPTYKTSSGSYVLHGGVTVR 127

Query: 88  PQKESNLEMNSEVLESWMNY--------------QSTTSLSINTELALFS---------R 124
              + +L   S+ + +  +Y               S     ++ EL              
Sbjct: 128 QTVQCSLSSISDTITTLNDYAKKIGSKSSQGTMFTSNLEFEVSAELKGVGVKTTVPPLVD 187

Query: 125 VNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTP--TSELSLGFTKALMDICDQL 182
                S E++  +    + + V T        YTV+ +P      S GF  +L+ + +  
Sbjct: 188 AAFSSSNEYRNNELFFSQKRGVLTLRDATCATYTVRISPFDPPPFSNGFVNSLIRLNNTD 247

Query: 183 EKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGI 242
           E N+      +    I  +GTH +     GA         +     + + Q        +
Sbjct: 248 ESNRAS----VVNDFIREFGTHFLQQTTMGARTAITRRYSADEFKLSTDDQIQKCNEDRL 303

Query: 243 AFLNIVNFKVETDYISQTSLTKDYLSNRTN----SRVQSFGGVPFYPGITLETWQKGITN 298
               I    V     S   +     S+  +      V S+G     P   L +W +    
Sbjct: 304 KLT-IAGVGVGRTSQSCNDIANSASSSSVDGFEREAVTSYGS---KPATDLVSWSQQKFE 359

Query: 299 HLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHP---------- 348
               I      L        +   P    K + K +   +  Y   N             
Sbjct: 360 SPSPIKMELSSLLNLFTATHMKNHPSINYKGILKWLGPLMYDYCEKNKVELGIKSCNPQT 419

Query: 349 --------GCTNVDSPNFNFQANMDDDSCDAKVTNF--TFGGVYQECTELSGDVLCQ 395
                    C        N   N+    C  K +      GG  Q+ T+ S    C 
Sbjct: 420 KNSCGWNDNCIPRQQVCNNNPNNIGYTCCTPKCSLLPCKNGGSCQDITDSSCTFRCS 476


>UniRef50_P07358 Complement component C8 beta chain n=25 Tax=Euteleostomi
           RepID=CO8B_HUMAN
          Length = 591

 Score = 96.1 bits (237), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 54/407 (13%), Positives = 114/407 (28%), Gaps = 69/407 (16%)

Query: 50  GWDNLRNVDMGRVMDLTYTNCKTTE----DGQYIIPDEVYT-IPQKESNLEMNSEVLESW 104
           G +   N   G V+D  Y     +     + ++  P  V +  PQ +   E   +  ES+
Sbjct: 178 GINLFTNSFEGPVLDHRYYAGGCSPHYILNTRFRKPYNVESYTPQTQGKYEFILKEYESY 237

Query: 105 MNYQSTTSLSINTELALFS--RVNGKFSTEFQRMKTLQVKD----------QAVTTRVQV 152
            +++   +  + ++       ++ G F                        ++V    + 
Sbjct: 238 SDFERNVTEKMASKSGFSFGFKIPGIFELGISSQSDRGKHYIRRTKRFSHTKSVFLHARS 297

Query: 153 RNRIYTVKTTP-TSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDA 211
              +   K  P +  L   F + +  +  +    + +        L  ++GTH IT    
Sbjct: 298 DLEVAHYKLKPRSLMLHYEFLQRVKRLPLEYSYGEYRD-------LFRDFGTHYITEAVL 350

Query: 212 GAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFL-----NIVNFKVETDYISQTSLTKDY 266
           G        +    +     + N V A A   F        V   +         +  + 
Sbjct: 351 GGIYEYTLVMNKEAMERGDYTLNNVHACAKNDFKIGGAIEEVYVSLGVSVGKCRGILNEI 410

Query: 267 LSNRTNSR------VQSFGGVPFYPG----------ITLETWQKGITNHLVAIDRAGLPL 310
                         V   GG   +              ++ W   +  +   I     PL
Sbjct: 411 KDRNKRDTMVEDLVVLVRGGASEHITTLAYQELPTADLMQEWGDAVQYNPAIIKVKVEPL 470

Query: 311 HFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDS-C 369
           +  +               + + ++ A+  +        C    +P       +   S C
Sbjct: 471 YELVTATDF-----AYSSTVRQNMKQALEEFQKE--VSSCH--CAPCQGNGVPVLKGSRC 521

Query: 370 DAKVTNFTFGGVYQECTELSGDVLCQNLEQKN-LLTGDFSCPPGYSP 415
           D              C   S  + C+   +KN  + G ++C   +S 
Sbjct: 522 DC------------ICPVGSQGLACEVSYRKNTPIDGKWNCWSNWSS 556


>UniRef50_P13671 Complement component C6 n=27 Tax=Tetrapoda RepID=CO6_HUMAN
          Length = 934

 Score = 95.7 bits (236), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 71/459 (15%), Positives = 132/459 (28%), Gaps = 102/459 (22%)

Query: 18  EADKPLGETGTTGFQICKNALKLPVLEVLP-------GGGWDNLRNVDMGRVMDLTYT-- 68
             +   G+      + C     +   +  P       G G+  L     G V+D ++T  
Sbjct: 159 NGENDCGDNSDE--RDCGRTKAVCTRKYNPIPSVQLMGNGFHFLAGEPRGEVLDNSFTGG 216

Query: 69  NCKTTEDGQ----YIIPDEVYTIP--QKESNLEMNSEVLESWMN---------------- 106
            CKT +  +    Y +P  +  +    + +  ++ ++  +   +                
Sbjct: 217 ICKTVKSSRTSNPYRVPANLENVGFEVQTAEDDLKTDFYKDLTSLGHNENQQGSFSSQGG 276

Query: 107 --------YQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYT 158
                   Y S  S +IN   A    +      +   ++  +V      T          
Sbjct: 277 SSFSVPIFYSSKRSENINHNSAFKQAIQASHKKDSSFIRIHKVMKVLNFT---------- 326

Query: 159 VKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQE 218
                   LS  F KAL  +   LE N       L   +  ++GTH  TS   G      
Sbjct: 327 -TKAKDLHLSDVFLKALNHLP--LEYNSA-----LYSRIFDDFGTHYFTSGSLGGVYDLL 378

Query: 219 DHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTK-------DYLSNRT 271
               S  L ++  ++        I     V F  +T    + +  K        ++    
Sbjct: 379 YQFSSEELKNSGLTEEEAKHCVRIETKKRVLFAKKTKVEHRCTTNKLSEKHEGSFIQGAE 438

Query: 272 NSRVQSFGGVPFY-------------PGITLETWQKGITNHLVAIDRAGLPLHFFIKPDK 318
            S     GG   Y                T   W + +  +   ID    P+   ++   
Sbjct: 439 KSISLIRGGRSEYGAALAWEKGSSGLEEKTFSEWLESVKENPAVIDFELAPIVDLVR--- 495

Query: 319 LPGLPGPLVKKLSKTVETAVRHY-YTFNTHPGCTNVDSPNFNFQANMDDDS-CDAKVTNF 376
                 P        +  A++ Y   F+         +P  N        + C     + 
Sbjct: 496 ----NIPCAVTKRNNLRKALQEYAAKFDPC-----QCAPCPNNGRPTLSGTECLCVCQSG 546

Query: 377 TFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSP 415
           T+G   + C + S D       + N + G + C   +S 
Sbjct: 547 TYG---ENCEKQSPDY------KSNAVDGQWGCWSSWST 576


>UniRef50_D0FYH7 Complement component C6 n=1 Tax=Mustelus manazo RepID=D0FYH7_9CHON
          Length = 958

 Score = 94.2 bits (232), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 71/452 (15%), Positives = 129/452 (28%), Gaps = 78/452 (17%)

Query: 32  QICKNA---LKLPVLEVLPGG-----GWDNLRNVDMGRVMDLTY--TNCKTTEDG----Q 77
           + CK       L  ++ LPG      G++ L     G V++ TY    C T   G     
Sbjct: 192 EGCKIKRDPPCLRKVQPLPGAQLIGSGYNVLAGEMGGEVLNNTYYGKECVTMRSGIIGEL 251

Query: 78  YIIPDEVYTIPQKESNLE--MNSEVLESWMNYQSTTSLSINTELALFSRVN--------- 126
           Y +P  +  I    S+LE  + SE      +Y+S  S S        S  N         
Sbjct: 252 YRVPSNLENITFTVSDLEDDVTSEFYSDPSDYESKISSSSQHYGDHTSSFNIPILFGRRK 311

Query: 127 ---GKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT-SELSLGFTKALMDICDQL 182
               + ++ F  +     +  +   RV     +   +        S  F +AL ++  + 
Sbjct: 312 SKKTRRTSSFSEIIKASAQKDSAFVRVHKTIAVSEFRMNENKLHASETFLEALSNLPLEY 371

Query: 183 EKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGI 242
                     +   +  ++GTH  T+   G             +  +  +Q  +      
Sbjct: 372 HYA-------MYSRIFQDFGTHYFTAGKTGGVYDVLYQYDREEINSSGLTQAEMKECVKT 424

Query: 243 AFLNIVNF-KVETDYISQT------SLTKDYLSNRTNSRVQSFGG------------VPF 283
             +  V F KV       T            L     S     GG               
Sbjct: 425 ETVTRVLFIKVRRTKTKCTQNHMTEQTKGSILEAAEKSVSMVRGGRAEFAAALAWQKGKS 484

Query: 284 YPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYT 343
           +P    + W+  + ++   +D    P+   +K         P      + +E A+  Y  
Sbjct: 485 FPTEQYQHWKLSVQHNPTVVDFELRPILGLVK-------GIPCAVTKRRHLERAMMEYME 537

Query: 344 FNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLL 403
                 C+    PN      +++ SC       T+G   +   +     +          
Sbjct: 538 NFDPCRCS--PCPNNAKTVMVEN-SCVCVCKAGTYGDSCEHRVQGYHSTV---------Q 585

Query: 404 TGDFSCPPGYSPVHLLSQTHEEGYSRLECKKK 435
            G +SC   ++                 C   
Sbjct: 586 DGAWSCWSSWT----HCDASHRRTRSRRCNNP 613


>UniRef50_A7AM24 Predicted protein n=1 Tax=Babesia bovis RepID=A7AM24_BABBO
          Length = 1272

 Score = 93.8 bits (231), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 61/339 (17%), Positives = 103/339 (30%), Gaps = 45/339 (13%)

Query: 40   LPVLEVLPGGGWDNLRNVDM---GRVMDLTYTN-----------CKTTEDGQYI-IPDEV 84
            +P +E L G G+D L    +   G ++D  Y N            K  +D +Y  IP   
Sbjct: 941  IPAIEYL-GCGYDILYGNPLADDGTLVDPGYRNPIISFTLAHHKSKGKKDLKYANIP-GA 998

Query: 85   YTIPQKESNLEMNSEVLESWMNYQSTTSLSINTE-LALFSRVNGKFSTEFQRMKTLQVKD 143
            +  P         + +++S  +YQ   S+        +        S E           
Sbjct: 999  WIRPLVACQRSDETSIVKSISDYQKALSVDSEVGIGTVDESAKFALSAEITVFCWKLRCP 1058

Query: 144  QAVTTRVQVR-----NRIYTVKTTP-TSELSLGFTKALMDICDQLEKNQTKMATYL---- 193
               +++++V+        +       T EL   F KA  +          +         
Sbjct: 1059 STESSKLEVKQGKRVCSAFKKSFQNATKELKPNFKKAATECTTIRYAINPEYPDCKEVKP 1118

Query: 194  AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVE 253
               L   +GTH   ++  G  L +   V  +       + N+V A A     N + F   
Sbjct: 1119 WMQLFEMFGTHFTYNIKIGGRLTKISQVNLN--KKTNTNMNSVNAGATTQVRNEL-FGAS 1175

Query: 254  TDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLET---WQKGITNHLVAIDRAGLPL 310
                     TKD   N + + V   GG              W   I  H + I     PL
Sbjct: 1176 AGVGLSKGSTKDNTENISFTYVNVLGGRTIGNVEDENEYLEWINSIPEHPMPIRNQLAPL 1235

Query: 311  HFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPG 349
                  +           +L +T + A+ +Y   N    
Sbjct: 1236 AKLFDSE-----------ELKETYDDAMEYYVELNGLKT 1263



 Score = 78.8 bits (192), Expect = 7e-13,   Method: Composition-based stats.
 Identities = 46/295 (15%), Positives = 93/295 (31%), Gaps = 38/295 (12%)

Query: 39  KLPVLEVLPGGGWDNLRNVDMG---RVMDLTYTN--------CKTTEDGQYIIPDEVYTI 87
            +  LE L G G+D+ +++  G     +D  YT         C+        +P  V+  
Sbjct: 133 SVKGLEYL-GCGYDSTKSMPFGDEESFLDSGYTQPVVNFQWPCRNRS-KINPMPIGVWIR 190

Query: 88  PQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMK----TLQVKD 143
            +   +      ++++     S  S  +    +     N   +   Q  +       VK 
Sbjct: 191 QEPSCHRGHEKRMIKNKETLVSILSEDVE---SFLGIANFGVNYVMQNKEIAGMEDIVKK 247

Query: 144 QAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMAT-YLAELLILNYG 202
               TR                       K   D  ++   +        L +   +NYG
Sbjct: 248 HMNVTRAFENATKEIESYPD---------KEKCDTQEKYLSDAECKNYCELWKKFFMNYG 298

Query: 203 THVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSL 262
           THVI+ +  G  ++Q D + ++   + +++      S  +            +  +    
Sbjct: 299 THVISRITMGGKILQMDEMENTANENAESNDKKHNISVNVGV-----LSGSFNLNNTNEK 353

Query: 263 TKDYLSNRTNSRVQSFGGVPFYPGIT---LETWQKGITNHLVAIDRAGLPLHFFI 314
            +     + N +    GG  F P  T      W   I  + + I+    P+  F+
Sbjct: 354 QQKEKVKKKNGKFFIMGGDTFIPVDTPEGFRDWVDSIKENSMPINVELTPMSQFM 408



 Score = 71.4 bits (173), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 76/524 (14%), Positives = 152/524 (29%), Gaps = 87/524 (16%)

Query: 66  TYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRV 125
            YT     +D        ++   +   ++     V+++    ++    S +   +   + 
Sbjct: 445 NYTLG-VNKDNDSYDKMGIWLSNEFVCDVSYERTVVDTKQKLKTIMLSSKSEGGSGIFKS 503

Query: 126 NGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKN 185
           N K       +     K + V  R       Y +K          F  A       +E  
Sbjct: 504 NHKTVNTRDDIYNKLKKSRNVLVR------KYRLKECQG-----DFKVADCPTEKYVENM 552

Query: 186 QTKMAT---YLAELLILNYGTHVITSVDAGAALVQEDHVR-SSFLLDNQNSQNTVTASAG 241
             +  +           +YGTHV   +  G    +  +V       D    + T+  S+ 
Sbjct: 553 DDESCSGCISSWMRFFADYGTHVTRRISMGGIFRRFSNVSNRESKRDASKQKTTIKKSSS 612

Query: 242 IAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRV-QSFGGVPFYPGI---TLETWQKGIT 297
                  +   +    +++S +K     + +  V  + G  P    +     E W + + 
Sbjct: 613 -----WFHLVKKKSKKTKSSSSKVSSEGKEHDLVQYTVGPEPHNESMAPDVFEDWVRDVA 667

Query: 298 NHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPN 357
            + V ID    PL   +           +  +       A+ +Y                
Sbjct: 668 LNPVPIDVEYQPLSEIM-----------MENQAKNLYAKAIEYYTKLKGI---------- 706

Query: 358 FNFQANMDDDSCDAKVTNF--TFGGVYQECTELSGDVLCQN-----------LEQKNLLT 404
            + +  +  ++ ++ +++       V  +        +C             L +K  + 
Sbjct: 707 -DIKEKVSTETIESPISHLLKELTMVAVDGNPRVNQDICSGNSKIVVGFGVNLNEKKQIL 765

Query: 405 GDFSCPPGY--SPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWC 462
           G  +C  G   S   L+          L    K T+ I       +   V K        
Sbjct: 766 GLRTCHSGLLVSAYLLILYKRNSCILDLNKDVKSTIVIALCGESPNYDIVQKVTKGTSIL 825

Query: 463 VAAGQV--PDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFK 520
               +V  P+N  + FG +   +  NP     SCP G            C       G+ 
Sbjct: 826 DRYNEVQCPNNMVVGFGAI--IQFTNPFA-IVSCPKGGST---------C-------GYA 866

Query: 521 FSVPFGGFF-SCIMGNPLVNSDT---AKDVRAPSLKKCPGGFSQ 560
              P G  + SC   N    +     ++ +R+    +C  GF  
Sbjct: 867 HLGPHGLIWASCFPKNTRGLNLFDTKSRIIRSGKTLECDPGFKM 910


>UniRef50_C3YIK1 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3YIK1_BRAFL
          Length = 949

 Score = 93.8 bits (231), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 68/486 (13%), Positives = 130/486 (26%), Gaps = 88/486 (18%)

Query: 45  VLPGGGWDNLRNVDMGRVM-DLTYT-NCKTTEDGQ----YIIPDEV-YTIPQKESNLEMN 97
              G G++ L     G+V+ +  Y   C T   G     + +P+ +     Q  ++    
Sbjct: 228 AFAGSGYNILSGEVAGKVLENRLYGGTCNTVYSGDHGKSFRLPENLQNYRFQVLADNSFA 287

Query: 98  SEVLESWMNYQSTTSL------SINTELALFS-RVNGKFSTEFQRMKTLQVKDQAVTTRV 150
           +    S   Y   T         +    + F  + +G  S   Q   T +V + A     
Sbjct: 288 ATAYNSAEEYYRETRSNSQRNVKVGGSGSFFVIKASGGVSHS-QSRMTHEVIESAQKIDS 346

Query: 151 QVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVD 210
           +    + TV+         G   + + +    +             LI ++GTH  +S  
Sbjct: 347 KYFKVVNTVELAQFKMRRNGLNPSDIFLRRMKDLPVY-YNYLDYSFLIEDFGTHYFSSGS 405

Query: 211 AGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY---ISQTSLTKDYL 267
            G           + L  +  ++    +               +       + +L++   
Sbjct: 406 LGGQYEYVYRYSRADLSHSGLTEEEQKSCLSAEAKASFFSFSGSSSGSRCKENALSQRNS 465

Query: 268 SNRT----NSRVQSFGGV-------PFYPGITLET---WQKGITNHLVAIDRAGLPLHFF 313
            + T     S     GG         F  G   +    W + +  +   I     P+   
Sbjct: 466 GSFTLSASESFSHVKGGSSESAGQLAFANGPNPQKYEAWIQDVKRNPAIISYEITPISEL 525

Query: 314 IKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKV 373
           +       +  P      + +E A+  Y  F  +  C   +S   N QA M    C    
Sbjct: 526 L-------VGIPYADIKRRNMEKALVEYLHF--YHSC-KCNSCQNNGQAIMIGTECVCVC 575

Query: 374 TNFTFGGVYQ-------ECTELSGDVLC-------------------QNLEQKNLLTGDF 407
              T+G   +         T + G+  C                   +            
Sbjct: 576 KAGTYGISCELGTQVDNVGTAVHGNWACWGSWAPCSKSCGSGQRVRRRTCSNPTPRNNGQ 635

Query: 408 SCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQ 467
           +CP              +      C  +      C T C+  +      +       AG 
Sbjct: 636 TCP-------------GQDSETETCNSQ-----PCLTQCQPGYYSRTG-YAPCRACPAGA 676

Query: 468 VPDNSG 473
                G
Sbjct: 677 FQTLPG 682


>UniRef50_P02748 Complement component C9b n=13 Tax=Theria RepID=CO9_HUMAN
          Length = 559

 Score = 93.0 bits (229), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 43/329 (13%), Positives = 80/329 (24%), Gaps = 49/329 (14%)

Query: 85  YTIPQKESNLE------MNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKT 138
             I +K SN                       T+ SI+       R +   +  +Q   +
Sbjct: 226 SIIQEKTSNFNAAISLKFTPTETNKAEQCCEETASSISLHGKGSFRFSYSKNETYQLFLS 285

Query: 139 LQVKDQAVTTRVQVRNRIYTVKTTP-TSELSLGFTKALMDICDQLEKNQTKMATYLAELL 197
              K + +   V+    +           L+  F   +  +    EK       Y A   
Sbjct: 286 YSSKKEKMFLHVKGEIHLGRFVMRNRDVVLTTTFVDDIKALPTTYEK-----GEYFA--F 338

Query: 198 ILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF-----LNIVNFKV 252
           +  YGTH  +S   G        +  + +         +    G         + ++   
Sbjct: 339 LETYGTHYSSSGSLGGLYELIYVLDKASMKRKGVELKDIKRCLGYHLDVSLAFSEISVGA 398

Query: 253 ETDYISQTSLTKDYLSNRTNS------RVQSFGGVPFYPGI--------------TLETW 292
           E +        +    N T+            GG   Y                     W
Sbjct: 399 EFNKDDCVKRGEGRAVNITSENLIDDVVSLIRGGTRKYAFELKEKLLRGTVIDVTDFVNW 458

Query: 293 QKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTN 352
              I +  V I +   P++  +                 + +E A+  Y    +   C  
Sbjct: 459 ASSINDAPVLISQKLSPIYNLVPVKM------KNAHLKKQNLERAIEDYINEFSVRKCHT 512

Query: 353 VDSPNFNFQANMDDDSCDAKVTNFTFGGV 381
             +             C      F F G+
Sbjct: 513 CQN-GGTVILMDGKCLCACP---FKFEGI 537


>UniRef50_UPI000180B791 PREDICTED: similar to thrombospondin type 1 repeat containing protein
            n=2 Tax=Ciona intestinalis RepID=UPI000180B791
          Length = 1167

 Score = 91.9 bits (226), Expect = 9e-17,   Method: Composition-based stats.
 Identities = 55/385 (14%), Positives = 115/385 (29%), Gaps = 50/385 (12%)

Query: 33   ICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTN--CKTTE----DGQYIIPDEVY- 85
             C++  K+P  EV+ G G D    V    ++D +  N  C T      D  Y +P  +  
Sbjct: 793  ECEDETKIPNAEVV-GEGLDVATLVKTVPLLDNSKNNGYCDTVYYKDDDVTYQMPYNLET 851

Query: 86   TIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSR-------------VNGKFSTE 132
             +P +        +  +S          +I  +                        ++ 
Sbjct: 852  FLPVEHEITSFEVKSQKSLAALLEDMQENIQNKHEYAGTSEQLPLIHEAVPYATAGNNSL 911

Query: 133  FQRM--KTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMA 190
             +++   +   + +  + R       + +K      L+  F  +L ++   +E N+    
Sbjct: 912  IEKLILGSHDNEYKYFSIRAVAIIAEFKLK-DNDLILNPEFKSSLDNLP--VEYNEKMYM 968

Query: 191  TYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDN----QNSQNTVTASAGIAFLN 246
                  ++  YGTH  T    G           + L D+    +  +  +   A I FL 
Sbjct: 969  D-----ILNQYGTHYYTKGIIGGKYEYIYEYSEAALDDSGLTDKEQRKCLENEARIEFLG 1023

Query: 247  IVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVP-FYPGITLE-------TWQKGITN 298
                       +       + +  T++     GG P     + +         W   I +
Sbjct: 1024 EDASIRNIKCSNLGKSRTLFTNAATSAVSFVSGGNPVIAETLNINSGAKKFVKWMNSIPS 1083

Query: 299  HLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNF 358
            +   ++    P+   + P               + +E A+ HY        C      N 
Sbjct: 1084 NPAILNYKISPISELVGPR------VSHANVTRQNLEMALLHYMQEYNPTSCAEQVCHNG 1137

Query: 359  NFQANMDDD-SCDAKVTNFTFGGVY 382
              +  ++   SC     +  +G   
Sbjct: 1138 AMKKVVNTGKSCLCVCLDGWYGSQC 1162


>UniRef50_C3PWZ7 Putative uncharacterized protein n=2 Tax=Bacteroides sp. 9_1_42FAA
           RepID=C3PWZ7_9BACE
          Length = 491

 Score = 91.5 bits (225), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 40/262 (15%), Positives = 92/262 (35%), Gaps = 44/262 (16%)

Query: 105 MNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT 164
            N++ + +  ++ +       +G  S  F+         +    + +V           T
Sbjct: 111 SNFKGSVAA-MDIKKDAEGFFSGTLSAGFKSASKYSYSSKYSFAKAEV-----------T 158

Query: 165 SELSLGFTKALMDI-CDQLEKN-QTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVR 222
            +    F  A +++    L  N  + +  Y A+ ++  YGTHV+T++  G + +     +
Sbjct: 159 KKQRKYFVDADVELLSRYLSSNFVSDLGKYSADQIVAKYGTHVLTNITVGGSYIAYY--K 216

Query: 223 SSFLLDNQNSQNTVTASAGIAF-LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGV 281
           S+ + +N  ++   T SAG  + ++ V    +  + + T    +  ++     +Q  GG 
Sbjct: 217 SAIIEENTGTEKKQTVSAGAKYNMSKVGLDFDGTWSTTTITEANKKNSDWTCTIQCVGGT 276

Query: 282 P------------FYPGITLETWQKGITNH---LVAID-RAGLPLHFFIKPDKLPGLPGP 325
                            I +  W + + +    LV +D  A  P++  +           
Sbjct: 277 TSGTTITLAPNQGPTTTINIGAWSQSVDDTHSRLVDVDWNATYPIYDLVSDPV------- 329

Query: 326 LVKKLSKTVETAVRHYYTFNTH 347
                   ++ AV  Y      
Sbjct: 330 ----KKADLKLAVEKYINSKKI 347


>UniRef50_B5X0R1 Complement component C7 n=8 Tax=Euteleostei RepID=B5X0R1_SALSA
          Length = 845

 Score = 91.5 bits (225), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 66/414 (15%), Positives = 121/414 (29%), Gaps = 62/414 (14%)

Query: 31  FQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMD-LTYT-NCKTTEDGQYIIPDEVYTIP 88
           F +C N    P +E L G G+D +     G V++  +Y   C+    G   +   +Y +P
Sbjct: 128 FPVCNNDKPPPNVEQL-GLGFDAVTGKQRGSVINTKSYGGQCRAVFSGDNKV---LYRLP 183

Query: 89  QKESNLEMNSEVLESWMN--YQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAV 146
           Q         +V   + +  Y S+ S + +      +         +   +T +      
Sbjct: 184 QSTLRYNFEVKVQNDFSDEFYTSSWSYAKDEVKRETTTGTTTGYKNYDFHQTEEKNRNNH 243

Query: 147 TTRVQ--VRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTH 204
              V+  V    +         LS  F K L  +    +    +M       ++  +GTH
Sbjct: 244 LLVVKNDVEVAQFQNNAPGYLSLSEEFWKVLATLPTVYDYATYRM-------VVERFGTH 296

Query: 205 VITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTK 264
            ++    G        +                         +    V            
Sbjct: 297 YLSEGTLGGYFHALLSIDQETAKQMAKVTWKYNECTKTKHRILF---VSWTTEKCRKDEN 353

Query: 265 DY--------LSNRTNSRVQSFGG--------------VPFYPGITLETWQKGITNHLVA 302
            Y          + T  +V   GG               P       + W + +      
Sbjct: 354 KYTLPNPPSISRSDTVKKVDVEGGATAHIAALKALDLNTPGKNWDMYKNWAESVRTFPAV 413

Query: 303 IDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQA 362
           I R   PL+  +K      +    VK+    ++ A+  Y     HP C     P  N   
Sbjct: 414 IKRKMRPLYELVK-----EVQCAGVKRF--HLKRAIEQYLNER-HP-C--RCQPCRNNGL 462

Query: 363 NMDDD-SCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSP 415
            +     C       T G   ++  E+ G        Q+ ++ G +SC  G++ 
Sbjct: 463 VVMAGDKCSCICKPGTDGLACEKGKEVEG--------QEGVIHGSWSCWSGWTS 508


>UniRef50_A7RN26 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
           RepID=A7RN26_NEMVE
          Length = 198

 Score = 90.3 bits (222), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 34/202 (16%), Positives = 70/202 (34%), Gaps = 20/202 (9%)

Query: 40  LPVLEVLPGGGWDNLRNVDMG-----RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNL 94
             +L   P G  +    +D G     RV+ L + + KT+ DG+++I DEV    ++    
Sbjct: 6   YNILSGNPEG--EQTAQIDPGLMPKRRVLQLHFRHNKTSVDGKFLIADEVAFDYRRSCVD 63

Query: 95  EMNSEVLESWMNYQSTTSLSINTELA---LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQ 151
              + ++     YQ+  +  IN       + +      S  F+ +    + D  V    +
Sbjct: 64  VTETSIITGTEGYQTKLAAQINITGTANHVLADFAFSQSQRFKIIHRKTIIDHEVLYEEK 123

Query: 152 VRNRIYTVKT---TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITS 208
               +  V+      ++ L+  FT A+  +                   I  +GTH++  
Sbjct: 124 TTCSLGRVRYLLGRASTPLTQAFTDAVCRLPQLYS-------AIDYVTFIDKWGTHIVIG 176

Query: 209 VDAGAALVQEDHVRSSFLLDNQ 230
           +  G   ++             
Sbjct: 177 LQVGKQQIKRYKTTRREFARFS 198


>UniRef50_B0JZ32 C9 protein (Fragment) n=5 Tax=Tetrapoda RepID=B0JZ32_XENTR
          Length = 598

 Score = 89.9 bits (221), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 69/459 (15%), Positives = 128/459 (27%), Gaps = 81/459 (17%)

Query: 48  GGGWDNLRNVDMGRVMDLTYTN--CKTTEDGQ--YIIPDEVYTIPQKE-SNLEMNSEVLE 102
           G G + L         D  Y N  C    DG+  +  P  V  +  K  ++    +E   
Sbjct: 161 GDGLNILGMKPKRNPFDNEYFNGICDRVRDGKTYFRKPWNVAALVYKTRADKSFTTETYH 220

Query: 103 SWMNYQSTTSL--SINTELALFSRV----------NGKFSTEFQRMKTLQVKDQAVTTRV 150
              +  S      ++N + +L  ++                 + + K++Q   Q   T+ 
Sbjct: 221 DAKSVMSKIIEGLTVNVDASLSLKITPTEQKNLTVGASAGLGYSKNKSVQRLRQYSETKD 280

Query: 151 QVR-NRIYTVKTTPT------SELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGT 203
           +       TV+          + LS  F + +  +           A Y +  ++  YGT
Sbjct: 281 KTYMRVSGTVQLASFQMRTRGAMLSPTFIEDIKSLPRDY-----DKAEYFS--ILEMYGT 333

Query: 204 HVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTAS----AGIAFLNIVN-FKVETDYIS 258
           H   S   G        + S  +     +   VT      AG       N  KV+ +   
Sbjct: 334 HYTVSGTVGGKYDLVYVLDSIVMKSLDITTEDVTDCLKLNAGANIGGTENGAKVDVNPNV 393

Query: 259 QTSLTKDYLSNRTNSRVQSF------------GG---------------VPFYPGITLET 291
           +T +             ++             GG                P         
Sbjct: 394 KTDICNKGGGETETEPRRTQKPVIESIISFVDGGSVEYVTALEEKLNKKEPVADVDDYIQ 453

Query: 292 WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCT 351
           W   + +    I+    P+   I  D             ++ +E A+  Y   ++   C 
Sbjct: 454 WASSLKDSPTVINSKSNPIISLIPTD------IKDAYIKTRNLERAIEEYLDEHSVCKC- 506

Query: 352 NVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSC-- 409
                         +  C   +    + GV   C  +  D+       K  + G + C  
Sbjct: 507 QPCQNGGKVMVIDGECICKCTLH---YEGV--ACQNIKSDLFSTP---KQPIDGGWGCWT 558

Query: 410 -PPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCE 447
             P      +++    +     E  K C  +   K  CE
Sbjct: 559 ISPNCVDGEIIATRKCDNPVPQEGGKPCHGQQTKKIPCE 597


>UniRef50_A7AT92 Mac/perforin domain containing membrane protein n=1 Tax=Babesia
           bovis RepID=A7AT92_BABBO
          Length = 559

 Score = 89.9 bits (221), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 41/312 (13%), Positives = 83/312 (26%), Gaps = 52/312 (16%)

Query: 52  DNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTT 111
           D+L +           ++   T   +++ P   +  P         SE + +  + QST 
Sbjct: 81  DDLGHRSPIVDFYWAKSDVGVTNSLKWLQPLGGWVRPITACG---ESETV-TVGSQQSTN 136

Query: 112 SLSINTELALF----SRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTP--TS 165
             S   +   F       +G     +  +        +           Y     P    
Sbjct: 137 EESTQFDFGGFAMSSGLGSGALRAGYTDISGKTQHISSKQYTNSYYCFTYAAGMPPYFNW 196

Query: 166 ELSLGFTKALMDICDQLEKNQTKMATYLAEL------------LILNYGTHVITSVDAGA 213
           E +  F  AL ++  +++           +               L +GTHV T +  G 
Sbjct: 197 ETTSDFDIALNELPKEVKSFDQCTVELYKKKSKKCGSISKWVDFFLQFGTHVTTEIQLGG 256

Query: 214 ALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNS 273
            +++   + ++ +     S   V  +        +  +V     S+       L      
Sbjct: 257 KIIRLLTIPNNAMDSFLKSGLNVDVAVKAVISGAL-LEVNEKLNSEQQKAIKELQ----- 310

Query: 274 RVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKT 333
                         +L  W+  +    + I     PL  FI                 + 
Sbjct: 311 ------------DDSLLKWKSTVPIFPMPIRTIYAPLDMFIHSSY------------KEA 346

Query: 334 VETAVRHYYTFN 345
              A+  Y   N
Sbjct: 347 YRNALNFYIKLN 358


>UniRef50_C3ZTX2 Putative uncharacterized protein n=4 Tax=Branchiostoma floridae
           RepID=C3ZTX2_BRAFL
          Length = 1359

 Score = 89.5 bits (220), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 54/365 (14%), Positives = 111/365 (30%), Gaps = 56/365 (15%)

Query: 26  TGTTGFQICK-NALKLPVLEV--LPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYI--- 79
            G   ++  +     L ++E     G G+D  R          T    K +   +Y    
Sbjct: 212 PGDPCYKAKRPLPPCLNLMEGCYYIGVGFDG-RGEYSSVSRRKTVIQRKCSLKKKYHGEE 270

Query: 80  IPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTL 139
           +PD++      +S++   S V E   +++           + +       S      K+ 
Sbjct: 271 VPDQMNVHGVYDSDVS--SRVFEGRESFRQFLQQKAGVSFSGWGFQGSVNSAWGGSSKSE 328

Query: 140 QVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLIL 199
           +    ++     +R  I+  +  PT +L+L F +  + +       + K      +  I+
Sbjct: 329 KQMFMSLIEADIIRYEIFLDEVKPT-DLTLSFLRDFLSLPKNFIIGKAK-----LQEFII 382

Query: 200 NYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQ 259
            YGTH I S   G +      +  +       S  + + SA  ++  + +         +
Sbjct: 383 RYGTHYIKSAKFGGSF----QLYKTQEATKSESLESFSVSAQASYSGMFSAGAHYGRKEE 438

Query: 260 TSLTKDYLSNRTNSRVQSFGGVPFYPGI-----------TLETWQKGITNHLVAIDRAGL 308
           +       S+ T+  ++  GG     GI           T   W K + ++   I+    
Sbjct: 439 SGSASSQKSSSTHLVIE--GGDQKVAGIVADFYTTSFKDTFTEWLKSVPSYPKPIEMFMG 496

Query: 309 PLHFFIK------------------------PDKLPGLPGPLVKKLSKTVETAVRHYYTF 344
            L   +                          D         + K    +E A+  Y   
Sbjct: 497 TLSELLNLNFKLLFPFDVSDAADGCFSKKYCDDTSVEEFQLSMDKKRLALERAIAVYMEE 556

Query: 345 NTHPG 349
              P 
Sbjct: 557 GPIPT 561


>UniRef50_P10643 Complement component C7 n=24 Tax=Tetrapoda RepID=CO7_HUMAN
          Length = 843

 Score = 88.4 bits (217), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 85/479 (17%), Positives = 147/479 (30%), Gaps = 76/479 (15%)

Query: 34  CKNALKLPVLEVLPGGGWDNLRNVDMGRVMD-LTYT-NCKT--TEDGQ--YIIPDEVYTI 87
           C      P +E L G G++ L      RV++  ++   C+   + DG+  Y +   V + 
Sbjct: 128 CDIDKPPPNIE-LTGNGYNELTGQFRNRVINTKSFGGQCRKVFSGDGKDFYRLSGNVLSY 186

Query: 88  P-QKESNLEMNSEVLESWMNYQSTTSLS------INTELALFSRVNGKFSTEFQRMKTLQ 140
             Q + N + N E   S  +Y   TS          +     S  +  +++    +   +
Sbjct: 187 TFQVKINNDFNYEFYNSTWSYVKHTSTEHTSSSRKRSFFRSSSSSSRSYTSHTNEIHKGK 246

Query: 141 VKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILN 200
              Q +     V    +        +L+  F K L  +    + +           LI  
Sbjct: 247 S-YQLLVVENTVEVAQFINNNPEFLQLAEPFWKELSHLPSLYDYSA-------YRRLIDQ 298

Query: 201 YGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQT 260
           YGTH + S   G       +V S  L  N  +           +      K  +    + 
Sbjct: 299 YGTHYLQSGSLGGEYRVLFYVDSEKLKQNDFNSVEEKKCKSSGWH--FVVKFSSHGCKEL 356

Query: 261 SLTKDYLSNRTNSRVQS-----FGGVPFYPGIT-------------LETWQKGITNHLVA 302
                  S   N+ ++       GG  F  G++                W + +TN    
Sbjct: 357 ENALKAASGTQNNVLRGEPFIRGGGAGFISGLSYLELDNPAGNKRRYSAWAESVTNLPQV 416

Query: 303 IDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQA 362
           I +   PL+  +K      +P   VKKL   ++ A+  Y        C     P  N   
Sbjct: 417 IKQKLTPLYELVK-----EVPCASVKKL--YLKWALEEYLDEFDPCHC----RPCQNGGL 465

Query: 363 NMDDDS-CDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQ 421
              + + C      +TFG   ++   +          Q   + G +SC   +SP      
Sbjct: 466 ATVEGTHCLCHCKPYTFGAACEQGVLVGN--------QAGGVDGGWSCWSSWSPC----- 512

Query: 422 THEEGYSRLECK--------KKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNS 472
              +     EC         + C  +    T CED           + C     VP   
Sbjct: 513 VQGKKTRSRECNNPPPSGGGRSCVGETTESTQCEDEELEHLRLLEPH-CFPLSLVPTEF 570


>UniRef50_Q969A3 Complement component C6 n=1 Tax=Branchiostoma belcheri
           RepID=Q969A3_BRABE
          Length = 921

 Score = 88.0 bits (216), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 68/478 (14%), Positives = 134/478 (28%), Gaps = 89/478 (18%)

Query: 46  LPGGGWDNLRNVDMGRVM-DLTYT-NCKTTEDGQ----YIIPDEV----YTIPQKESNLE 95
             G G++ L     G+V+ +  Y   C T   G     + +P+ +    + +    S   
Sbjct: 205 FAGSGYNILSGEVAGKVLENRLYGGTCNTVYSGDHGKSFRLPENLQNYRFQVLADNSFAT 264

Query: 96  M---NSEVLESWMNYQSTTSLSINTELALFS-RVNGKFSTEFQRMKTLQVKDQAVTTRVQ 151
               ++E         S  ++ +    + F  + +G  S   Q   T +V + A     +
Sbjct: 265 TAYNSAEEYYRETRSNSQRNVKVGGSGSFFVIKASGGVSHS-QSRMTHEVIESAQKIDSK 323

Query: 152 VRNRIYTVKTTPT----SELSLG--FTKALMDICDQLEKNQTKMATYLAELLILNYGTHV 205
               + TV+        S+L+    F + + D+                  LI ++GTH 
Sbjct: 324 YFKVMNTVELAQFKMRRSDLNPSDIFLRRMKDLPVY-------YNYLDYSFLIEDFGTHY 376

Query: 206 ITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY---ISQTSL 262
            +S   G           + L  +  ++    +               +       + +L
Sbjct: 377 FSSGSLGGQYEYVYRYSRADLSHSGLTEEEQKSCLSAEAKASFFSFSGSSSGSRCKENAL 436

Query: 263 TKDYLSNRT----NSRVQSFGGVPFYPG----------ITLETWQKGITNHLVAIDRAGL 308
           ++    + T     S     GG     G             E W + +  +   I     
Sbjct: 437 SQRNSGSFTLSASESFSHVKGGSSESAGQLAFANGPNPEKYEAWIQDVKRNPAIISYEIT 496

Query: 309 PLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDS 368
           P+   +       +  P      + +E A+  Y  F  +  C   +S   N QA M    
Sbjct: 497 PISELV-------VGIPYADIKRRNMEKALVEYLHF--YHSC-KCNSCQNNGQAIMIGTE 546

Query: 369 CDAKVTNFTFGGVYQ-------ECTELSGDVLC-------------------QNLEQKNL 402
           C       T+G   +         T + G+  C                   +       
Sbjct: 547 CVCVCKAGTYGISCELGTQVDNVGTAVHGNWACWGSWAPCSKSCGSGQRVRRRTCSNPTP 606

Query: 403 LTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAY 460
                +CP           +  E  +   C  +C    + +T            F+  
Sbjct: 607 RNNGQTCPG--------QDSETETCNSHPCLTQCQPGYYSRTGYAPCRACPPGAFQTL 656


>UniRef50_B0S6X4 Novel protein similar to vertebrate complement component 7 (C7)
           (Fragment) n=3 Tax=Danio rerio RepID=B0S6X4_DANRE
          Length = 867

 Score = 87.2 bits (214), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 77/472 (16%), Positives = 140/472 (29%), Gaps = 63/472 (13%)

Query: 34  CKNALKLPVLEVLP-----GGGWDNLRNVDMGRVMD-LTYT-NCKTTEDGQ----YIIPD 82
           CK +    + +  P     G G+D  +    G V++  ++   C+ T  G     Y +P 
Sbjct: 152 CKISENTNLQKPPPNVEITGQGFDAAKREARGTVINTKSFGGLCQKTFSGDHKDFYRLPQ 211

Query: 83  EVYTIP-QKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQV 141
            V +   Q  +  +   E   S  +Y         T    +   +  F  E  + K+  +
Sbjct: 212 SVLSYSFQVTAKNDFTDESFASSWHYLHHYEKHEKTTGTDYGHDDYVFHDELSQSKSKNL 271

Query: 142 KDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNY 201
                  +  V    +  K      LS  F KAL+ +    +             ++  +
Sbjct: 272 M----IIKSDVEVGQFKNKDPEYLPLSEDFWKALVALPVVYDYAA-------YRNVLERF 320

Query: 202 GTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTS 261
           GTH I+    G             +   ++ +         +   +   +  T      +
Sbjct: 321 GTHYISEGSLGGHFKLYLMASEDVISKLKSEKRDYEDCVVTSHSVMFFIRWSTKTCKTDT 380

Query: 262 --LTKDYLSNRTNSRVQS--FGGVP--------FYPGI------TLETWQKGITNHLVAI 303
              TK +  +   S +++   GG P        FY         T   W   +  +   I
Sbjct: 381 IDETKTFYKSIPESDMKTDIIGGDPGFIAKLSMFYKYDVKENARTFSQWSGSLKYYPRII 440

Query: 304 DRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQAN 363
                 LH  +K      +P   +K+    ++ A+  Y T      C        N    
Sbjct: 441 KSKLRSLHELVK-----EVPCAGLKRF--LLKRAIETYLTEKHSCQCRECQ----NNGLR 489

Query: 364 MDDD-SCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQT 422
           + D   C       T G   Q C   +        EQ  ++ GD++C   +S      ++
Sbjct: 490 VLDGNVCKCVCKPGTSG---QACEYGTAYD-----EQPGVIHGDWACWSSWSSCSGGQKS 541

Query: 423 HEEG--YSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNS 472
                        + C      +T CED   +         C      P  S
Sbjct: 542 RRRSCTRPAPSGGRDCIGNTEERTACEDEEELNHLRSMEPHCFDDSIKPRES 593


>UniRef50_UPI000180B792 PREDICTED: similar to complement component C6 n=1 Tax=Ciona
            intestinalis RepID=UPI000180B792
          Length = 1045

 Score = 87.2 bits (214), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 50/307 (16%), Positives = 86/307 (28%), Gaps = 33/307 (10%)

Query: 91   ESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRV 150
            +S +E   E   S   Y  + S  +     L     G  + + ++M      D      V
Sbjct: 749  KSVIEAIQESFRSMQEYADS-SAELTQMSQLVGHAAGGDNAKLEKMIKDGYSDDYKYFSV 807

Query: 151  QVRNRIYTVKTTPT-SELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSV 209
            +    +   +       L+  F + L ++             YL   L+  YGTH  T  
Sbjct: 808  KTVITVAMFQMRDDNLLLNEDFEEDLNELHSWY-----DKVEYL--RLLEKYGTHYYTEG 860

Query: 210  DAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNI-VNFKVETDYISQTSLTKDYLS 268
              G         R + L+    +                +   V+ +       +K + +
Sbjct: 861  TLGGQYKFIYKFRKADLVKADLTDTEQRQCLEDDAKIKLLGADVDIN-DRCNFNSKSFTN 919

Query: 269  NRTNSRVQSFGGV--------PFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLP 320
            N   S     GG               +L  W   +  H   ++    PL   I    + 
Sbjct: 920  NAVQSVSFVDGGEANAVSSLSVNSDEKSLTEWTNSVIMHPAIVEYKIAPLSQLIDSRIIQ 979

Query: 321  GLPGPLVKKLSKTVETAVRHYY-TFNTHPGCT----NVDSPNFNFQANMDD---DSCDAK 372
            G      KK    +ETA+ H+   F      +         N   Q  + D     C   
Sbjct: 980  G------KKKKANMETALLHFMKKFEPIRCNSFNAGVKRCRNGAKQKVVKDGRECVCLCP 1033

Query: 373  VTNFTFG 379
               +  G
Sbjct: 1034 AGLYGAG 1040


>UniRef50_UPI0000E47361 PREDICTED: similar to apextrin, partial n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E47361
          Length = 436

 Score = 87.2 bits (214), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 40/265 (15%), Positives = 82/265 (30%), Gaps = 28/265 (10%)

Query: 26  TGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVY 85
           T   G Q     +   +++  P GG  N   VD G      Y          Y IPD+V 
Sbjct: 43  TSPPGVQN-FLGVGYDIIDGNPEGGEINNGGVDPGLKGIEMYG---------YAIPDQVS 92

Query: 86  TIPQKESNLEMNSEVLESWMNYQSTTSLSINT-ELALFSRVNGKFSTEFQRMKTLQVKDQ 144
            + ++ S    + ++     +Y        N  +               +    +  +++
Sbjct: 93  YVDRQSSVSTSSRDIFHGTQSYVQKLEKESNIRDYE-------SIQAGVEYRGLVYYENK 145

Query: 145 AVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTH 204
            V    + R   + +       L  GF      +     +  T    +L        GTH
Sbjct: 146 TVALEAEARYN-WELAEQEQYPLDNGFVVEACSLPASYHE--TNYMQFLQRR-----GTH 197

Query: 205 VITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTK 264
           V+TSV+ G+  ++     +   +         + S    F+   +  +  D     +   
Sbjct: 198 VVTSVNLGSRKIERYEEETQGFVHYARENVAKSTSLRAGFMG-YSIGLAVDMEEFKANLG 256

Query: 265 DYLSNRTNSRVQSFGG-VPFYPGIT 288
             +   + +   + G   P + G+ 
Sbjct: 257 AGMKFGSKTHTFTSGSFEPIHTGLD 281


>UniRef50_D2UX64 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2UX64_NAEGR
          Length = 708

 Score = 86.8 bits (213), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 44/278 (15%), Positives = 83/278 (29%), Gaps = 35/278 (12%)

Query: 77  QYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALF-------SRVNGKF 129
           ++ +PD +       +N+   S+ +ES        + S +   ++        + +N  F
Sbjct: 90  KFKVPDAIEVYDYVTTNVTKTSDTMESMSESLKYEASSYSFSFSVNVGVVGVSAGLNTSF 149

Query: 130 STEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT--SELSLGFTKALMDICDQLEKNQT 187
               Q       +         +R  IY     P    E +  F +AL  I +       
Sbjct: 150 GHIHQTF----AQSNLFMATGSIRGTIYQATLEPPTFLEQNPYFKRALAAIPNTPTAADL 205

Query: 188 KMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQN----SQNTVTASAGIA 243
                    LI  +G   ++    G        V    L         +Q ++T S G  
Sbjct: 206 DK----INTLIKYFGVSYVSKGVFGGKFNLITKVSDKILKSYDKSWCITQLSLTFSYGAY 261

Query: 244 FLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAI 303
              +  FK +TD         D+ +N         G        TL+ W + I      I
Sbjct: 262 SFGMSGFKNKTDIHVNN----DFANNAKTDMFFVGGDFTLQSNETLKEWYQSIPGQPSLI 317

Query: 304 DRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
                 +   +  + +            K +E  +++Y
Sbjct: 318 GGEFNLISDLVDNNAV----------KKKNLEAILKNY 345



 Score = 68.7 bits (166), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 48/337 (14%), Positives = 97/337 (28%), Gaps = 49/337 (14%)

Query: 45  VLPGGGWDNLRNVDMGRVMDLTYTNCKTT------EDGQYIIPDEVYTIPQKESNLEMNS 98
            L G G+D         +      +  TT      +D Q+ +P  V      ES    ++
Sbjct: 381 ALIGSGFDTFTLTPRLSLFKQAPDSKATTWTNPIYKDIQFAVPGNVLVRNNAESYYANST 440

Query: 99  EVLESWM----NYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRN 154
            V  +       Y+  +S S    L+  SR    ++  ++        + +       R 
Sbjct: 441 FVALTKQEYEYQYREHSSKSGMFGLSHHSRDVFIYNYRYEF-------EDSYQLNTFRRI 493

Query: 155 RIYTVKTTPT--SELSLGFTKALMDICDQLEKNQTKMAT--YLAELLILNYGTHVITSVD 210
             Y +   P    +L+         + D L              +  I  YGT V+T   
Sbjct: 494 SWYDLSLDPLCLFDLNNRLEPFAKRMIDSLPATGGDQKEVRDKYKKFIDYYGTAVVTKTT 553

Query: 211 AGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKV-------ETDYISQTSLT 263
            G  +  + + +         S + +   +G +FL+I   K        +         +
Sbjct: 554 MGGGIFFKVNFKKDLTK--TLSIHEIHEQSGWSFLHIFGEKSTHDFYLKKLSQQFIQHSS 611

Query: 264 KDYLSNRTNSRVQSFGGVPFYPG-----------ITLETWQKGITNHLVAIDRAGLPLHF 312
            ++ +   +   +  G  P  P            ++ E +   I      ++    P+H 
Sbjct: 612 VEFNTQGGSWTPEINGVRPTGPNALNIIDSPEGYMSWEDYANSIKYDPYPVNYELQPIHT 671

Query: 313 FIKPDK--------LPGLPGPLVKKLSKTVETAVRHY 341
                         L         +   +   A + Y
Sbjct: 672 IFADKAKQGIMKSVLDEYLQEKYNQKPASFSRAGKEY 708


>UniRef50_B9X257 Similar to terminal complement component n=1 Tax=Halocynthia
           roretzi RepID=B9X257_HALRO
          Length = 585

 Score = 86.5 bits (212), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 64/415 (15%), Positives = 126/415 (30%), Gaps = 65/415 (15%)

Query: 42  VLEVLPGG-----GWDNLRNVDMGRVMDLT-YTNCKTT-----EDGQYIIPDEVYTIPQK 90
            L  +PG      G+D L     G  + +  + +C+        D  Y +P  V +  Q+
Sbjct: 159 YLMGIPGIERFSSGFDILTGNLKGETLSMNPFGSCRRVLKSGETDTYYRLPGNVNSFTQE 218

Query: 91  ESNLEMNSEVLESWMNYQSTTSLS----------INTELALFSRVNGKFSTEFQ-RMKTL 139
            S  +    ++ +     ++              I  ++A+      K    +       
Sbjct: 219 FSISQTGGTIVTNASGLITSLQNQLLENPYVGGVIGGDVAMVGLNQEKHIQNYILESDRT 278

Query: 140 QVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLIL 199
           Q K  +V T   VR    ++K      L   F K L ++      ++         LLI 
Sbjct: 279 QNKFVSVMTGTNVRVFKVSLKEASQLNLGTAFMKRLYELPANYSYSRD-------ILLIQ 331

Query: 200 NYGTHVITSVDAGAALVQEDHVRSSFLLD-------NQNSQNTVTASAGIAFLNIVNFKV 252
           ++GTH I S   G +  Q       +L D       N + ++ +       F   +N   
Sbjct: 332 DFGTHYIASATLGGSYGQTSKYSRCWLEDGYEFDFENNDWKDNLVTCEKENFKQQMNPNF 391

Query: 253 ETDYISQTSLTKDYLSNRTNSRVQSFGGVP--------FYPGITLETWQKGITNHL--VA 302
               I  +   +  +       ++  GG                  TW   + +    + 
Sbjct: 392 TPSGICLSKSGEKLVDQADGITIKIVGGSVSVASTLKTSLNTQNWITWINSVVSSPSLLP 451

Query: 303 ID-RAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYT-FNTHPGCTNVDSPNF-- 358
            D     P+   +    L  +     K++   +  A++ Y   +N    C++ +   +  
Sbjct: 452 FDNFVLQPISSLVDVSSL-QIDQNKKKQVKTNINQAIQDYLKPYNATLYCSDSNISEYCV 510

Query: 359 -----------NFQANMDDDSCDAKVTNFTFGGVYQ---ECTELSGDVLCQNLEQ 399
                          N D      +    T G  Y+    C  + G  +C  +  
Sbjct: 511 SKCGSGDVVLIKNGTNADPAYNSLRYLTGTGGSQYKCICLCNSIPGFDVCSGIRT 565


>UniRef50_A7AT97 Mac/perforin domain containing protein n=1 Tax=Babesia bovis
           RepID=A7AT97_BABBO
          Length = 420

 Score = 84.9 bits (208), Expect = 9e-15,   Method: Composition-based stats.
 Identities = 39/316 (12%), Positives = 84/316 (26%), Gaps = 40/316 (12%)

Query: 48  GGGWDNLRNVDMG------------RVMDLTY--TNCKTTEDGQYIIPDEVYTIPQKESN 93
           G G+D ++   MG             +++  +  +    +     + P   +  P     
Sbjct: 82  GIGYDAIKGNTMGGEESLLDPGYRAPIINFNWRKSAEGYSPSLNAVYPLYGWVRPVYSCG 141

Query: 94  LEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVR 153
                + +E+    +   S + + +      V    S +++         +         
Sbjct: 142 RSSKIQEIENLDELKKVFSANASIKGD-IPAVAFSASAKYKNASEKLA-HKTERMDTTSS 199

Query: 154 NRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGA 213
                    P  +       A   I D  +     +  ++       +GTH +  +  G 
Sbjct: 200 FMEAMKSLEPLPDTVKKMCSAHDMIDDMTKSECIPLKKWI--KFFEMFGTHYVHQLLLGG 257

Query: 214 ALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYL-SNRTN 272
            L+Q   + +S L   +N    V        +        +  +    +   Y       
Sbjct: 258 KLIQTLKINASKLQALKNDSIDVDL------VVSSVLGSSSASLLADKVVNKYKLDELGA 311

Query: 273 SRVQSFGGVPFYPGITLET---WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKK 329
             +   GG      IT      W   +  + + I   G  L   +             K 
Sbjct: 312 KSITVIGGNMPNTPITDAEYAIWGNSVAENPMPIGIVGDSLKNLMD------------KN 359

Query: 330 LSKTVETAVRHYYTFN 345
           L  +   A+  Y   N
Sbjct: 360 LRDSYSLAIHKYAELN 375


>UniRef50_UPI000196958C hypothetical protein BACCELL_01585 n=1 Tax=Bacteroides
           cellulosilyticus DSM 14838 RepID=UPI000196958C
          Length = 397

 Score = 84.5 bits (207), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 37/282 (13%), Positives = 90/282 (31%), Gaps = 44/282 (15%)

Query: 87  IPQKESNLEMNSEVLESWMNYQSTTSLSINT---ELALFSRVNGKFSTEFQRMKTLQVKD 143
           +  +      +++   S +   +  S S+ +   +       +G  +T F+         
Sbjct: 87  VIDQRCFAGADAQSFLSQIITDTNFSGSVGSLPEKKDKEGFFSGTITTGFKTSSKYFYSS 146

Query: 144 QAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDIC-DQLEKNQTKMATYLAELLILNYG 202
           +    R +V  +                   +  +    L      +  Y A+ ++  YG
Sbjct: 147 KYSFARAEVFKKQRRYLLNTD----------IETLSKYLLSSFVEDLNKYSADKIVEMYG 196

Query: 203 THVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF-LNIVNFKVETDYISQTS 261
           THV+T++  G         +S+ + +N +++ T   SAG  + L+ +       +     
Sbjct: 197 THVLTNITVGGKYTAYY--KSAIIEENSSTEKTEIVSAGAKYNLSNIGLDAHGSWSKTEV 254

Query: 262 LTKDYLSNRTNSRVQSFGGVPFYPG------------ITLETWQKGITN---HLVAID-R 305
             ++  ++     +++ GG                  I L  W + + +    L  ++  
Sbjct: 255 EERNKKNSNWECYIKALGGSTSGTTITLAPEQGPSFSINLGAWTESVDDQHSRLFDVNWN 314

Query: 306 AGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTH 347
           A  P++  I                 + ++ AV  Y      
Sbjct: 315 ATYPIYDLISDPI-----------KKQEMKEAVFRYIDSKKI 345


>UniRef50_Q4T1D8 Chromosome undetermined SCAF10660, whole genome shotgun sequence.
           (Fragment) n=16 Tax=Clupeocephala RepID=Q4T1D8_TETNG
          Length = 584

 Score = 84.5 bits (207), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 66/386 (17%), Positives = 118/386 (30%), Gaps = 50/386 (12%)

Query: 30  GFQICKNALKLPVLEVLPGGGWDNLRNV-DMGRVMDLTYT-NCKTTEDGQ----YIIPDE 83
           G +   +  K P    L G G+D L      G +  +++   C+    G     Y +P  
Sbjct: 138 GSRSSCDLDKTPPNSDLVGKGYDILTGDLRAGVINTVSFGGQCRKVFSGDHKILYRLPQN 197

Query: 84  VYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKD 143
           +    +    + +N E  +       +   SI +   L+     KF       +      
Sbjct: 198 IL---RYNFEVTVNDEESDESFESSWSYMQSIQSNA-LWGHDRRKFHKTVTESRAH---- 249

Query: 144 QAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGT 203
           + +  + +V    +         L+ GF +AL  +    +    +        L   YGT
Sbjct: 250 RLIILKNKVELAQFQNTAPEYLTLAEGFWRALSSLPTTYDYAAYRQ-------LFQTYGT 302

Query: 204 HVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYIS-QTSL 262
           H  +    G        +    L     +               +  KV+T      +S 
Sbjct: 303 HYFSEGSLGGEYQALLELTQHALATTSTTSREYERCWRKVKRRFLRKKVKTVCEKLTSST 362

Query: 263 TKDYLSNRTNS--RVQSFGGVP----FYPGITLE----------TWQKGITNHLVAIDRA 306
              Y ++  N   +V   GG P    F   + LE           W   + +    I++ 
Sbjct: 363 AASYGTSMRNVPIKVDVVGGNPGLKRFLSILDLENPEENGRKYDDWASSVKDFPQIIEQK 422

Query: 307 GLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDD 366
             PL+  +K      +    +KKL   ++ A+  Y +   HP C     P  N    +  
Sbjct: 423 VRPLYELVK-----EVECAGLKKL--HMKQALEEYLSAE-HP-C--RCRPCHNNGRPLLL 471

Query: 367 DS-CDAKVTNFTFGGVYQECTELSGD 391
            S C       T G   Q    +   
Sbjct: 472 GSQCVCVCRLGTSGAACQSGAAVGEQ 497


>UniRef50_UPI000194DE7A PREDICTED: similar to complement protein C9 n=1 Tax=Taeniopygia
           guttata RepID=UPI000194DE7A
          Length = 618

 Score = 83.8 bits (205), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 66/458 (14%), Positives = 124/458 (27%), Gaps = 85/458 (18%)

Query: 48  GGGWDNLRNVDMGRVMDLTYTN--CKTTEDGQ----YIIPDEVYTIPQKESNLEMNSEVL 101
           G G + L    M    D  + N  C+   DG     Y  P  V  +       +  S V 
Sbjct: 185 GHGINVLGMQPMASPFDNDFFNGLCERVRDGNTRTYYRKPWNVAVLTYDTKADKTFSSVY 244

Query: 102 ES---------WMNYQSTTSLSIN-----TELALFSRVNGKFSTEFQRMKTLQVKDQAVT 147
                      ++  Q   S+  +     T+ +  +   G F  ++++        Q+ T
Sbjct: 245 YHDRVKMLREVYIEKQKYFSVDASLKYTPTDGSNKNASEGHFKYDYRKNYAFGSILQSYT 304

Query: 148 TRVQVRNR--------IYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLIL 199
            R Q             + +++     L+  F   L  +       +     Y     + 
Sbjct: 305 ERNQTFLHVNGQIQLGRFQIRSR-DVRLTDSFLDDLKFLP-----AEYDKGEYF--KFLE 356

Query: 200 NYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIV---NFKVETDY 256
           +YGTH   S   G        + +  +     +   V    G      +   N +   + 
Sbjct: 357 DYGTHYAVSGTVGGRYELVYVLDNYAMSRLGITVEDVKKCLGYHLDANIVYKNIQANFNV 416

Query: 257 ISQTSLTKDYLSNRTNSRVQSF--------GGVPFYP---------------GITLETWQ 293
            S              +             GG   +                      W 
Sbjct: 417 DSGKCENIYSREKSEANDNAVIDDVLSLVEGGKIDFSVKIKEMLLRGAKAVDVEDYIEWA 476

Query: 294 KGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNV 353
           K + +  V I +   P+H  +       +         + +E A+  Y T  +   C   
Sbjct: 477 KSLVDAPVVIQQRPSPIHTLV------PVKIRDAYLKKQNLERAIEDYITEYSVCKCE-- 528

Query: 354 DSPNFNFQANMD-DDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPG 412
             P  N    +  D  C    +++  G   Q         + ++   K +  G +SC   
Sbjct: 529 --PCKNGGTLVLVDGVCTCLCSSYFKGLACQ---------IPKSTLVKVVTDGGWSCWSA 577

Query: 413 YSPVHLLSQTHEEGYSRL---ECKKKCTLKIFCKTVCE 447
           +S       T     +        + C  +   K  CE
Sbjct: 578 WSACINGESTRTRQCNNPAPGSDGRPCQGESIEKRPCE 615


>UniRef50_UPI0001555301 PREDICTED: similar to Complement component 8, alpha polypeptide,
           partial n=1 Tax=Ornithorhynchus anatinus
           RepID=UPI0001555301
          Length = 517

 Score = 83.0 bits (203), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 66/412 (16%), Positives = 120/412 (29%), Gaps = 73/412 (17%)

Query: 22  PLGETGTTGFQICKNALKLPVLE-VLPGGGWDNLRNVDMGRVMDLTYT-NCKT----TED 75
           P  E  T GF +      LPVL+    GG  +++ N   G+  +  Y   C+      +D
Sbjct: 114 PGAEAVTLGFNVLTQESALPVLDPTFFGGRCESVYN---GQWREFRYDPACERLHYGDDD 170

Query: 76  GQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQST-----------------------TS 112
             +  P  V        +    ++   SW  Y+                           
Sbjct: 171 KYFRKPHNVLFY-----HFTAQADSGFSWETYEDVSHLISALETDKSRNLGVTVGVGLVK 225

Query: 113 LSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFT 172
             +  E+ L          +  +    +V+   V T VQ               L     
Sbjct: 226 NPVTVEVGLGLSDGVNLLKKLAKYSEQEVEFIRVVTTVQTARFR---MRRDDLVLDEDLL 282

Query: 173 KALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNS 232
           +AL ++ D  +         L   L+  +GTH +TS   G        +    +     +
Sbjct: 283 QALEELPDHYDSG-------LYSRLLHRFGTHYVTSGTVGGVFEFILVLNKDKMEKIGIT 335

Query: 233 QNTVTAS----AGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNS------RVQSFGGV- 281
           + TV++      G+ + N V+   +          +    N            +  GG  
Sbjct: 336 RETVSSCFGGSLGLTYSNKVDLNGKLKGNLCQKDGEKSKENVLKELGVEDVISRVRGGNL 395

Query: 282 -------PFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTV 334
                            W + +  +   +D    PL   ++   L G P P  ++L + +
Sbjct: 396 GPASGLLDLQSQHLYRAWGRSLKYNPALVDFELRPLGEVVRRASL-GFPEPRRRRLGRHL 454

Query: 335 ETAVRHYYT-FNTHPGCTNVDSPNFNFQANMDDDS-CDAKVTNFTFGGVYQE 384
           + A+  +   FN          P  N    +   + C         G   QE
Sbjct: 455 DRALEAFLADFNACR-----CGPCLNGGRPLLLGTRCACLCPAAFRGPACQE 501


>UniRef50_Q4UAZ8 Perforin-related protein, putative n=4 Tax=Theileria
            RepID=Q4UAZ8_THEAN
          Length = 1219

 Score = 83.0 bits (203), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 42/355 (11%), Positives = 92/355 (25%), Gaps = 65/355 (18%)

Query: 20   DKPLGET---GTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDG 76
              PL +       GF+              P   +  +   +      ++Y+N       
Sbjct: 904  GNPLSDPELLVDPGFRD-------------PIISYSIMFKKEK-LFRKISYSNIT----- 944

Query: 77   QYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTS--LSINTELALFSRVNGKFSTEFQ 134
                    +  P  E     +  V++S   Y+   S    I    ++        S  + 
Sbjct: 945  ------NAWIRPLIECKRSNSRSVVDSMEKYKDMISVDSDIGVS-SIDESAKFSLSANYS 997

Query: 135  RMKT--LQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMA-- 190
             +       K++    +         +    + +++  F  A+  +      +       
Sbjct: 998  EINDLLKNNKNKIYVDKSYCFLLEAALPIHNSLKITKSFATAMNKLSKDFSNHTKDCNPI 1057

Query: 191  TYLAEL-------------LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVT 237
             Y  +              L   +GTH   ++  G  +        S   + + ++ +  
Sbjct: 1058 KYTDDKNSKDCKEIKKWMDLFEQFGTHFSYNIKLGGRITYITQEEGS--KEEKENEKSGG 1115

Query: 238  ASAGIAF-LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVP---FYPGITLETWQ 293
            A  G     +     +E +        K    N +       GG+P            W 
Sbjct: 1116 AKIGHKLQKDNKGIGIEGNVQLIFGNKKGENKNLSFKYTNILGGLPVSDINKESEYVKWI 1175

Query: 294  KGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHP 348
            K +  + + I     P+    K   L             + + A R Y   +   
Sbjct: 1176 KSVYKYPMPIRTQFAPISKIFKSKALKD-----------SYDEAFRFYLNTSKVK 1219



 Score = 68.4 bits (165), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 48/309 (15%), Positives = 97/309 (31%), Gaps = 45/309 (14%)

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA 120
            V+    +     +  +  +P  V+   +        S V++S  +     +  I TE  
Sbjct: 36  PVISFENSTSVVGKGSEINLPLGVWIRNESLCYR--TSSVIKSEND---KVNSKIFTEDI 90

Query: 121 LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICD 180
             + VN ++  E + +  L  ++     ++        +  +    L       L  I +
Sbjct: 91  KLNMVNYEYKLENKSLNKLLTRNNLRIKKINCSIHTSGMIISYQWNLKKSILILLNKIQN 150

Query: 181 QL------------EKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLD 228
           +L            + NQ  +  Y   +    YGTHV+T +  G  +++           
Sbjct: 151 KLVNDSGHSSSNNSQLNQKNIEKYWYNIF-NTYGTHVLTKITLGGKVIEI---------- 199

Query: 229 NQNSQNTVTASAGIAFLNIVNFKV-ETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPG- 286
           N    +  T      F N  +    +T   S +    + L      ++  FGG       
Sbjct: 200 NTADGSENTTKDTSIFGNKFDLNFFKTSLNSISKDNIENLDKNEQEKIMIFGGNAITTNR 259

Query: 287 --------------ITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSK 332
                         +  + W + I  + V I     PL +FI           L +K   
Sbjct: 260 KRTNNYGEINYVKKLDKQKWIETIKYNPVPIKFELTPLSYFIY-QNFSSSNPQLNEKEGN 318

Query: 333 TVETAVRHY 341
            +   +++Y
Sbjct: 319 KLNLIIKNY 327



 Score = 65.7 bits (158), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 24/167 (14%), Positives = 51/167 (30%), Gaps = 18/167 (10%)

Query: 194 AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVE 253
                 +YGT +   +  G  + +  +++      N+  +   T      F ++  +K E
Sbjct: 517 WVQFFKDYGTSLTKQITMGGVINKFYNLKRYDGSMNKEYKKK-TVKESSTFFHLSKYKSE 575

Query: 254 TDYISQTSLTKDYLSNRTNSRVQSFGGVPF---YPGITLETWQKGITNHLVAIDRAGLPL 310
           +     +  +             + G  P         +  W + +  +   ID   +PL
Sbjct: 576 SMEEKNSGESDKEELEEVY--TLTIGPEPPGNVANSNVISDWLEKVIQNPTPIDFELVPL 633

Query: 311 HFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPN 357
              I    L            K  E A+++Y           V++ N
Sbjct: 634 IQIIPDKYL------------KVYENALKYYQKLYNISDLNGVNTVN 668


>UniRef50_B1ASJ8 Complement component 8, beta subunit n=3 Tax=Murinae
           RepID=B1ASJ8_MOUSE
          Length = 523

 Score = 82.6 bits (202), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 51/390 (13%), Positives = 114/390 (29%), Gaps = 61/390 (15%)

Query: 69  NCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGK 128
           NC+          ++ + I +  S + + +   E  +      +             N +
Sbjct: 153 NCRRIYKNCQREMEQYWAIDRLASGINLFTNTFEGPVLDHRYYA--GGCSPHYILDTNFR 210

Query: 129 FSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTK 188
                +     Q K     + ++V +     +   +  L   F + +  +  +    + +
Sbjct: 211 KPYNVESYTPQQSKFLHARSVLEVAHYKLKSR---SLMLHYEFLQRVKSLPLEYSYGEYR 267

Query: 189 MATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF---- 244
                   L+ ++GTH IT    G        +    +     + + VTA AG +F    
Sbjct: 268 D-------LLRDFGTHFITEAVLGGIYEYTLIMNKDAMEQGDYTLSHVTACAGGSFGIGG 320

Query: 245 -------LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFY----------PGI 287
                     V+ K  +D + + +      +   +  V   GG                 
Sbjct: 321 MVYKVYVKVGVSAKKCSDIMKEINERNKRSTMVEDLVVLVRGGTSEDITALAYKELPTPE 380

Query: 288 TLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTH 347
            +E W   +  +   I     PL+  +               + + ++ A+  + +    
Sbjct: 381 LMEAWGDAVKYNPAIIKIKAEPLYELVTATDF-----AYSSTVKQNLKKALEEFQSE--V 433

Query: 348 PGCTNVDSPNFNFQANMDDDS-CDAKVTNFTFGGVYQECTELSGDVLCQNLEQKN-LLTG 405
             C    +P       +   S C+         G +Q          C+   +K+  + G
Sbjct: 434 SSC--RCAPCRGNGVPVLKGSRCECICP-----GGFQ-------GTACEVTYRKDIPIDG 479

Query: 406 DFSCPPGYSPVHLLSQTHEEGYSRLECKKK 435
            +SC   +S     S  H+      +C   
Sbjct: 480 KWSCWSDWSAC---SGGHKT--RHRQCNNP 504


>UniRef50_UPI00015558C0 PREDICTED: similar to Perforin-1 precursor (P1) (Lymphocyte
           pore-forming protein) (PFP) (Cytolysin), partial n=1
           Tax=Ornithorhynchus anatinus RepID=UPI00015558C0
          Length = 511

 Score = 81.5 bits (199), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 36/225 (16%), Positives = 61/225 (27%), Gaps = 29/225 (12%)

Query: 168 SLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLL 227
           S   ++AL  +    + N T    Y +  LI  +GTH  TSV  G  +     +R     
Sbjct: 160 SPALSQALSSLPP--QYNLTSRGGYRS--LIQTFGTHYATSVRLGGRVRLVTALRLCLAT 215

Query: 228 DNQNSQNTVTASAGIAF-LNIVNFKVETDYISQTSLTKDYL----SNRTNSRVQSFGG-- 280
            +  S   + A          +  +   +   +      +          S  ++ GG  
Sbjct: 216 LDGVSPEALRACLSEEAREGWLQAQGAGNSSCRALPLGGFRGPFYGAYHESHEEAVGGSQ 275

Query: 281 --------VPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSK 332
                    P         W K + +    I     PLH  + P               +
Sbjct: 276 RGVDGLLVPPVANDTDFAAWMKSLHSVPGVISSTVAPLHTLLDPR----------DPQRE 325

Query: 333 TVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFT 377
            +  AV  Y    +         P     +  +   C    T  T
Sbjct: 326 ALRLAVTDYVAEESLDPGCPGGCPGGGAWSPREPCVCRCPGTEST 370


>UniRef50_Q6PFT2 Complement component 6 n=9 Tax=Clupeocephala RepID=Q6PFT2_DANRE
          Length = 885

 Score = 81.5 bits (199), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 62/413 (15%), Positives = 107/413 (25%), Gaps = 88/413 (21%)

Query: 48  GGGWDNLRNVDMGRVMDLTY--TNCKTTEDGQ--YIIPDEVYTIPQKESNLEMNSEVLES 103
           G G+D       G V+D ++  +NC   +  +  Y I   +     K          +E+
Sbjct: 177 GFGFDAAAEQMRGAVLDNSFMGSNCTVEKQKRNFYRISANIERYEVK----------VET 226

Query: 104 WMNYQSTTSLSINTELA----LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTV 159
             ++Q   + S   +LA        V      +    +  QV     T +V+        
Sbjct: 227 LEDFQPKETKSQKIDLANEPLYREAVKASQQKDSVFYRVHQVIA-TSTFKVKSS------ 279

Query: 160 KTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQED 219
                  LS  F + L  +   LE N       L   +   +GTH  +S   G       
Sbjct: 280 ----DLYLSDPFLQFLNSLP--LEYNYA-----LYRHIFQLFGTHYFSSGTLGGKYDLLF 328

Query: 220 HVRSSFLLDNQNSQNTVTASAG---IAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQ 276
                 L      ++                 N   + +     S+   Y  +   +  +
Sbjct: 329 QFDREELKTFGLKESDSEYCLSDDDTLVTFFYNRHKQRNTCGNISMKTKYEGSMVKASER 388

Query: 277 SF----GG--------VPFYPGITLE-----TWQKGITNHLVAIDRAGLPLHFFIKPDKL 319
                 GG             G++ +      W K    + V I+   LPL   ++    
Sbjct: 389 CITSVQGGRTEFAAALAWEKKGVSPQSTVYTDWIKSTIENPVVINYELLPLVNLVR---- 444

Query: 320 PGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFG 379
                       +    A+  Y T      C     PN    A +    C       T+G
Sbjct: 445 ---GISCAVTKRRHFHRALEEYQTE--FDSCKCAPCPNNARPA-LSGTECLCICQTGTYG 498

Query: 380 GVYQE----------------------CTELSGDVLCQNLEQKNLLTGDFSCP 410
              ++                      C         +         G   CP
Sbjct: 499 SNCEKRAPDYTSVEVDGHWSCWSSWSPCDATLKKHRSRTCSNPAPQRGGKPCP 551


>UniRef50_P79755 Complement component C9 n=10 Tax=Euteleostei RepID=CO9_TAKRU
          Length = 586

 Score = 80.7 bits (197), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 53/414 (12%), Positives = 113/414 (27%), Gaps = 68/414 (16%)

Query: 83  EVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL----------FSRVNGKFSTE 132
              T+ ++ ++ E+  +            S+ ++  L+            + +    S E
Sbjct: 197 NYQTLVEETASREIYEDSYSLLREMLKEMSIKVDAGLSFKFKSTEPSMSNNSLKLDASLE 256

Query: 133 FQ------RMKTLQVKDQAVTTRVQVRNRIYTVKTT-PTSELSLGFTKALMDICDQLEKN 185
           ++       +  L         RV+ R ++ T +      +++  F   +  +  + EK 
Sbjct: 257 YEKKTMIKDVSELTNIKNKSFMRVKGRLQLSTYRMRSHQLQVADEFVAHVKSLPLEYEKG 316

Query: 186 QTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFL 245
                  +    + +YGTH   +  +G        +    +     ++  +     I   
Sbjct: 317 -------IYYAFLEDYGTHYTKNGKSGGEYELVYVLNQDTIKAKNLTERKIQECLKIGIE 369

Query: 246 NIVNF------KVETDYISQTSLTKDYL----------------SNRTNSRVQSFGGVPF 283
                      K          +T                       +     +      
Sbjct: 370 AEFATTSVQDGKAHAKLNKCDDVTTKSQGDVEGKAVVDNVMTSVKGGSLESAVTMRAKLN 429

Query: 284 YPGI----TLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVR 339
             G+    T + W + I +    I+    P++  I  D       P        ++ A  
Sbjct: 430 KEGVMDIATYQNWARTIASAPALINSEPEPIYMLIPTD------IPGANSRIANLKQATA 483

Query: 340 HYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQ 399
            Y     +  C      N    A + D  C    +N  F G+   C    GD       +
Sbjct: 484 DYVAE--YNVCKCRPCHNGGTLA-LLDGKCICMCSNL-FEGL--GCQNFKGDKARVPAAR 537

Query: 400 KN-LLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRV 452
                 G++SC   +S      Q  +   +R  C  +  L   C+         
Sbjct: 538 PAVTQEGNWSCWSSWS----NCQGQKRSRTRY-CNTEGVLGAECRGEIRSEEYC 586


>UniRef50_A5CTM8 Putative uncharacterized protein n=1 Tax=Clavibacter michiganensis
           subsp. michiganensis NCPPB 382 RepID=A5CTM8_CLAM3
          Length = 470

 Score = 80.3 bits (196), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 45/275 (16%), Positives = 100/275 (36%), Gaps = 28/275 (10%)

Query: 61  RVMDLTYTNCKTTEDG--QYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTE 118
           ++ D +     TTE    +Y IP  +       S  E  S    +   YQ + + S+   
Sbjct: 40  QIFDWSKAEWGTTEINGTEYRIPKLMNAEGVAGS--EYVSIYGNTVEEYQQSLAASVAVS 97

Query: 119 LALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSL----GFTKA 174
            +         S E Q   +   + +   +RV+   +++++   P+ +L       F +A
Sbjct: 98  GSNMF---FSGSLETQFGSSSMRRSENAFSRVEQVVKLWSIGLPPSKKLRELLSGSFLEA 154

Query: 175 LMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQN 234
           L  +      +  + A Y  +  +  +G   ++ +  G        + +S +      + 
Sbjct: 155 LDGLPAAASTS-EEQAEY--KGFLDTWGAFYLSGMLIGGK-----TLFTSSVNKLTVDRT 206

Query: 235 -TVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVP------FYPGI 287
            +++ +A +++ ++       D I   S    + S+ +N+   +FGG P      F   +
Sbjct: 207 LSISVTADLSYKSVTGQISNEDKIKYASQLSQFASS-SNTVKNAFGGNPALASRVFDGRV 265

Query: 288 TLETWQKGITNHLVAIDRAGL-PLHFFIKPDKLPG 321
             + W   +  + V +   G  PL         P 
Sbjct: 266 QYDEWSASVAQNPVIVRFDGTRPLTGVWTLCSTPE 300


>UniRef50_D1B2B8 Membrane attack complex component/perforin/complement C9 n=1
           Tax=Sulfurospirillum deleyianum DSM 6946
           RepID=D1B2B8_SULD5
          Length = 466

 Score = 79.5 bits (194), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 38/277 (13%), Positives = 87/277 (31%), Gaps = 46/277 (16%)

Query: 89  QKESNLEMNSEVL--ESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAV 146
           +K+     +++V+  E+ M Y S  +  +  + +     +G  S +F             
Sbjct: 62  EKKIGTSSDTKVVVAENAMEYCSKLTAKLAVDASYKKVFSGALSLKFD--------YANS 113

Query: 147 TTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVI 206
            +        + +    +  L      A         +    + T   E LI  YGTH++
Sbjct: 114 CSSKYSFGSFFLIMRKASLSL---VVDANDLKPYVKAQFLEDVQTKSCETLIRLYGTHLM 170

Query: 207 TSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDY 266
           +++  G  L     V    +++++  + ++      +   IVN   E  Y      +   
Sbjct: 171 SNITLGGRL----EVLCRSIVEDERKEYSIEVGVKASVKKIVNVSSELSYD----ESVVS 222

Query: 267 LSNRTNSRVQSFGGVPFYPGI--------------TLETWQKGITNHLVAI----DRAGL 308
            +      +++ GG P    I                  WQ  + +  + +      + +
Sbjct: 223 KNKELTVNIETIGGDPSKCMIDSFDYTKASSELKSDFSAWQNSLNDENMTLVDMAKGSLI 282

Query: 309 PLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFN 345
            +   I  D        +     + +  A+  Y   N
Sbjct: 283 SIADLIPNDA-------VYASKKEALVLAIDRYLQEN 312


>UniRef50_C3ZX09 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZX09_BRAFL
          Length = 1320

 Score = 79.5 bits (194), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 48/355 (13%), Positives = 94/355 (26%), Gaps = 73/355 (20%)

Query: 48  GGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYI---IPDEVYTIPQKESNLEMNSEVLESW 104
           G G+D  R          T    K +   +Y    +PD +      ++     S V ES 
Sbjct: 259 GVGFDG-RGEYSSVSRRKTVIQRKCSLQKKYHKEELPDNMNVQGVYDTK--TTSLVFESR 315

Query: 105 MNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT 164
            +Y+ +         + +     + S       + + + Q   + ++      +   +  
Sbjct: 316 QSYRQSLQQKAGVSASGWG---FQASVNAAWGGSQKSEKQMFMSLIEADVISPSSIVSQE 372

Query: 165 SELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSS 224
             L                         +AE  I+ YGTH I S   G A      +  +
Sbjct: 373 KCLP------------------------VAEDFIIRYGTHFIKSAKFGGAF----RLFKT 404

Query: 225 FLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQ-------S 277
                  S  + + SA  ++  + +         ++       S  T   ++       +
Sbjct: 405 QEAAKSESLTSFSVSAQASYNGMFSAGGHYGRNEESGAASSEQSASTRVMIEGGDQKVGA 464

Query: 278 FGGVPFYPGI--TLETWQKGITNHLVAIDRAGLPLHFFIK-------------------- 315
                +  G   T   W K I ++   I+     L   +                     
Sbjct: 465 IVADFYTTGFKDTFLEWLKSIPSYPKPIEMFMGTLSELLNLNFKMLFPFDMSDAADGCFS 524

Query: 316 -----PDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMD 365
                   +      +  K    +E A+  Y      P  T+   P        D
Sbjct: 525 KNYCEDSSITEFQLSM-DKKRLALERAIAVYMEEGPVPT-TDFSLPGGKPGCQTD 577


>UniRef50_Q4U9X4 MAC/perforin, putative n=2 Tax=Theileria RepID=Q4U9X4_THEAN
          Length = 603

 Score = 78.4 bits (191), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 47/374 (12%), Positives = 94/374 (25%), Gaps = 72/374 (19%)

Query: 25  ETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGR---VMDLTY------------TN 69
           + G  G  I        +     G G+D++    +G    ++D  Y            + 
Sbjct: 11  DHGCPGLGIYSLYPFYVI--DYLGVGYDSIYANSVGGDSTLLDPGYRAPIIEFAWRKNSE 68

Query: 70  CKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTEL-----ALFSR 124
             +   G  + P   +  P    +       + +    + + S S          +    
Sbjct: 69  GYSPTLGS-LHPVGGWVRPVFSCSRSTKINEISNLEELKDSLSASTKLNGDIPENSFTGS 127

Query: 125 VNGK-----FSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT--SELSLGFTKALMD 177
           +  K            +   + K Q +  + +     Y V        E +  F   +  
Sbjct: 128 LEYKNAVMNSKYACNFLHDFRSKRQKIYNKTEQ-CVRYQVGIPLNLKWEYTEYFNHIVSK 186

Query: 178 IC----DQLEKNQTKMATYLAE----------LLILNYGTHVITSVDAG-------AALV 216
           +       +E         L++               +GTH    +  G         + 
Sbjct: 187 LPVLSSKLIENCNIDNKLNLSDEECKSIKPWIKFFEVFGTHFNNQLTLGIYIVVYCGKIN 246

Query: 217 QEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQ 276
           Q     SS L   +     + A       +              S +K  L      ++ 
Sbjct: 247 QTMVFDSSTLEGLKKKGIDIEAEVRTELGSE-----NGKLNLDMSGSKARLDEIGQKKMY 301

Query: 277 SFGGVPFYPGITLET---WQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKT 333
             GG      +       W + +  + + I      L   IKP   P            +
Sbjct: 302 VIGGKMPNFPMDDNEFAHWAETVAENPMPIGVVSTSLKTLIKPALHP------------S 349

Query: 334 VETAVRHYYTFNTH 347
            + A+  Y   N  
Sbjct: 350 YDQALHQYAILNGI 363


>UniRef50_Q6H964 Complement component C6 n=10 Tax=Clupeocephala RepID=Q6H964_ONCMY
          Length = 941

 Score = 78.0 bits (190), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 60/445 (13%), Positives = 111/445 (24%), Gaps = 76/445 (17%)

Query: 22  PLGETGTTGFQICKNALKLPVLEVLPGGGWDNLR-------NVDMGRVMDLTYT--NCKT 72
           P+ +    G           + E + G   DN+        N   G    L Y       
Sbjct: 181 PVEKRVVPGA-DLIGNGFDAMAEAMRGAVLDNMFMGDTCNLNRSRGSSYRLYYRVPANVE 239

Query: 73  TEDGQYIIPDEV--YTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFS 130
           + + +  IPD+      P     + + S  + +  +  S  S SI   +          S
Sbjct: 240 SFEIKVEIPDDFKQEPQPVYSETVNLASPPVSTRSDSSSGDSSSIWVPIFFVGSRRHHQS 299

Query: 131 TE---FQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQT 187
                 Q +   +  D       QV              L+  F + L  +   LE N  
Sbjct: 300 NTDTFKQAISASKKTDSQFFRVHQVLPVSRFRVKDSDLYLTEPFLQFLTSLP--LEYNYA 357

Query: 188 KMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNI 247
                L   +  ++GTH   S   G             L ++  ++              
Sbjct: 358 -----LYREIFKHFGTHYFASGTLGGHYDLLYQYSRLELKNSGLTEEHTKGCLKSESSMF 412

Query: 248 VNFKVETD-------YISQTSLTKDYLSNRTNSRVQSFGG-------------VPFYPGI 287
           +    ++                  ++ +   S     GG                    
Sbjct: 413 IIIYSQSSNVVRCSDNTMTQKHEGSFVQSSEKSFSMVRGGRTGEAAALAWEQKGAAPDST 472

Query: 288 TLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTH 347
           T + W K + ++   ++   LP+   +K         P      + +  A+  Y      
Sbjct: 473 TYKNWAKSLIDNPAVVEYELLPIINLVK-------GIPCAATKRRHLTRALVEYLE--DF 523

Query: 348 PGCTNVDSPNFNFQANMDDDS-CDAKVTNFTFGGVYQE------CTELSGDVLCQNLEQ- 399
             C    +P  N    +   + C       T+G   ++         + G   C      
Sbjct: 524 DSC--KCAPCPNNARAVLSGTDCQCICQTGTYGPNCEQRAQDYTSEAVDGYWSCWGTWSA 581

Query: 400 ---------------KNLLTGDFSC 409
                             L G   C
Sbjct: 582 CDASMKRHRTRECNNPAPLRGGKLC 606


>UniRef50_D0FYI7 Complement component C8 beta subunit n=1 Tax=Chimaera phantasma
           RepID=D0FYI7_9CHON
          Length = 582

 Score = 77.6 bits (189), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 46/367 (12%), Positives = 110/367 (29%), Gaps = 58/367 (15%)

Query: 48  GGGWDNLRNVDMGRVMDLTYTNCKTTE----DGQYIIPDEVYTI-PQKESNLEMNSEVLE 102
           G G++ L     G V+D  Y           + ++  P  +    P+ +++ + + +  +
Sbjct: 166 GSGFNILTESLEGPVLDNRYYAGSCAPHYIKNVRFRKPHNLDLHNPETKADYQFSLQKYD 225

Query: 103 SWMNYQ----STTSLSINTELALFSRVNGKFSTEFQRMKTL--------QVKDQAVTTRV 150
           S+ ++      T+  S++ +L L      +    ++                 +      
Sbjct: 226 SYSSFNENRFKTSEKSVSFKLELKIPDIFEIGVNYENNNYRKMASRFLDSSGSKRSMYHA 285

Query: 151 QVRNRIYTVKTTP-TSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSV 209
           Q+  ++   +  P    L   F + + ++        T         +  +YGTH ++  
Sbjct: 286 QMTLQVGRFQFKPRDLMLHHEFFRRISELP-------TTYNYGEYREIYKDYGTHFMSEG 338

Query: 210 DAGAALVQEDHVRSSFLLDNQNSQNTVTAS--AGIAFLNIVN---FKVETDYISQTSLTK 264
             G        + S+ +  +  S +    +   G      +N        +Y       K
Sbjct: 339 LLGGTYEYLWVLNSTQMEKDGYSLSDAANAMKVGAHLGGSINGVYVSGGFNYGQADKRLK 398

Query: 265 DYLSNRTNSR------VQSFGGVPFY----------PGITLETWQKGITNHLVAIDRAGL 308
           +      +S+      V   GG   +              ++ W + +      I    L
Sbjct: 399 EKGVGIASSKYTEDFIVFVRGGASQHVTALSHKDPPTEQLMQEWGEAVEYSPEVIKFKPL 458

Query: 309 PLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQA---NMD 365
           PL+  +             + +   ++ A+  + T   +  C    +P  N  A      
Sbjct: 459 PLYQLVTGQTF-----YNSRAIKANMKRALDEFLTE--YSLC--RCAPCHNNGAVFFTGT 509

Query: 366 DDSCDAK 372
              C   
Sbjct: 510 HCGCVCP 516


>UniRef50_UPI0001556468 PREDICTED: similar to MAC/perforin, putative, partial n=1
           Tax=Ornithorhynchus anatinus RepID=UPI0001556468
          Length = 360

 Score = 77.6 bits (189), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 45/298 (15%), Positives = 88/298 (29%), Gaps = 44/298 (14%)

Query: 48  GGGWDNLRNVDMGRV--------------MDLTYTNCKTTEDGQYIIPDEVYTIPQKESN 93
           G G+D      +G                     ++   T     + P   +  P++   
Sbjct: 74  GTGYDIFNANTLGESQGGEDLGYRAPIVDFSWEQSDIGVTNALDILQPIGGWIRPKQSCG 133

Query: 94  LEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVR 153
              +   + S  + +S  +  ++ +            T+++++     K +         
Sbjct: 134 ESESVTEITSTEDIKSLINADVSIDAHADDVGTVALGTKYKQLAKNLQKKENK------- 186

Query: 154 NRIYTVKTTPTSELSLGFTKALMDICDQ--------LEKNQTKMATYLAE--------LL 197
             +Y       +  +  F  A+  +              N+ K      E         +
Sbjct: 187 --LYANVYYCFTNYTNEFGDAISKLSKSTGIDGFKGCSVNKFKEKASSPECKHISPWMYM 244

Query: 198 ILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYI 257
              +GTHV+T V  G  L +   V  S +   Q+    V A+ G A   I    V     
Sbjct: 245 FSEFGTHVVTEVHLG-KLTRFLSVPVSSIKKLQDQGYNVDATIGAAIRGIEG-DVSLKVG 302

Query: 258 SQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETW---QKGITNHLVAIDRAGLPLHF 312
            Q     D  +  T       GG+ +   I+ ++    +  I    + I     PL F
Sbjct: 303 GQEKTNLDDFAKTTTLNFSVLGGIHYSKTISPQSLLKKKSSIPKAPMPIKTIVKPLKF 360


>UniRef50_C3ZKF3 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZKF3_BRAFL
          Length = 1305

 Score = 77.6 bits (189), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 55/366 (15%), Positives = 103/366 (28%), Gaps = 84/366 (22%)

Query: 60  GRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTS------- 112
           G V+    T C ++   +Y +PD +       ++ E  +    S   Y+           
Sbjct: 78  GYVLLYEETVCYSSY-KEYHVPDIMTVQGIYNTDAETYT--FYSIEEYRQYLEDKSAVNK 134

Query: 113 LSINTELALFSRVNGKFSTEF------------------QRMKTLQVKDQAVTTRVQVRN 154
            S +    L   +     + F                     +  +         V++  
Sbjct: 135 ASGHAGGGLVFGLVASAGSGFAAQFGGDNQASSVQASSQASAQLSETSTTTFMAMVELNV 194

Query: 155 RIYT--VKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAG 212
             Y   +       L+L F +  + +           A    +  IL +GTH ITS   G
Sbjct: 195 FRYEIFLDFVGPQNLNLAFLRDFLALPGTYFAIG---ADKEFQKFILRWGTHYITSAKFG 251

Query: 213 AALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSL---------- 262
             L     +  +    +Q+SQ T   +A   F  + +        S++S           
Sbjct: 252 GQL----KIIKTKEASSQDSQQTFATAAQSDFKKLFSTYSAQQTQSKSSSWWGGHEKKDE 307

Query: 263 ---------------------TKDYLSNRTNSRVQSFGG--------VPFYP---GITLE 290
                                 +      +N  ++  GG          FY    G +L+
Sbjct: 308 SAVSTGTASSGTEQSESVSEREQQSEYEFSNEVLEVQGGDQKIAAAITEFYTTSFGNSLK 367

Query: 291 TWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK-----KLSKTVETAVRHYYTFN 345
            W + I     A +   L +   +  +     P  +V      +   T +     YY  +
Sbjct: 368 DWLESIEEFPKAFEFRMLTITDLLDMNYDSFFPHGVVDYGCFGRKILTEDETGHKYYVED 427

Query: 346 THPGCT 351
              G T
Sbjct: 428 MVDGNT 433


>UniRef50_A7V074 Putative uncharacterized protein n=2 Tax=Bacteroides
           RepID=A7V074_BACUN
          Length = 656

 Score = 76.8 bits (187), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 50/363 (13%), Positives = 111/363 (30%), Gaps = 56/363 (15%)

Query: 1   MNSFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKL-PVLEVLPGGGWDNLRNVDM 59
           M      +   M+I    AD+ + E  +  F    N       +  + G G+D       
Sbjct: 1   MKKLFLFMSWVMLILSGCADEDIIERNSPSFPQSVNTRSAGDGVYDILGYGYDI-----T 55

Query: 60  GRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTEL 119
           G  +D   +     +  + +  ++    P K           +  +++ +  S S+    
Sbjct: 56  GPYLDTKSSRAIVFDTNKLL--EKGLITPYKLEESRFRYSSGKDVIDFTTNMSSSLQMST 113

Query: 120 ALFSRVNGKFSTEFQR--MKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMD 177
               +V G  S                      Q  +  Y +     + L    TK  ++
Sbjct: 114 PGILKVIGGASLNIAFGGNSHYNSDYSFAYCTQQYIDSRYRISEADINVLKTCLTKQFIE 173

Query: 178 ICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVT 237
                     +++TY  E ++  YGTHV+  +  GA        +S+          ++ 
Sbjct: 174 ----------RLSTYTPEQIVEEYGTHVLKDIYLGAKFEVYYMAKSTSSSKK----ESIN 219

Query: 238 ASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPF-----------YPG 286
           A  G +  ++     +  Y  ++    +   +       + GG P             P 
Sbjct: 220 AGLGASLFSLFKMDGKFQYD-ESLAITNKEQSLYY---FTIGGDPAVGVQGSLNPENSPS 275

Query: 287 ITLETWQKGI-TNHLVAIDR-----AGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRH 340
           I +  W   + ++    ID      + +P++  +                 +T++  + +
Sbjct: 276 IDIGKWMASVKSSTPKFIDVDNNSQSFIPIYELVTD-----------PTKKQTLKAYIDN 324

Query: 341 YYT 343
           Y  
Sbjct: 325 YIK 327


>UniRef50_C3ZT44 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
           RepID=C3ZT44_BRAFL
          Length = 1455

 Score = 75.7 bits (184), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 31/195 (15%), Positives = 63/195 (32%), Gaps = 22/195 (11%)

Query: 132 EFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMAT 191
           ++      +   Q    + + +  I+     P   LSL F +  +D+ +  +  + K   
Sbjct: 489 DYSSASRKKNLVQRFC-KNKRKYEIFLDDVRPD-TLSLDFLRDFLDLPESFKTGKQKK-- 544

Query: 192 YLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFK 251
              +  I+ YGTH I S   G +      V  +       S    +  A  ++  + +  
Sbjct: 545 -QLQKFIIRYGTHYIKSAKFGGSF----RVFKTQEASKTQSLTEFSVEAQASYSGMFSAG 599

Query: 252 VETDYISQTSLTKDYLSNRTNSRVQSFGGV--------PFYPG---ITLETWQKGITNHL 300
                   +   +   S   ++RV + GG          FY      T   W K I  + 
Sbjct: 600 ASFGMKGSSESAQ--SSKTASTRVTAEGGHQEVAAVVADFYTTGFKDTFSQWLKTIPTYP 657

Query: 301 VAIDRAGLPLHFFIK 315
             ++     +   + 
Sbjct: 658 KPVEMFMGTITELLN 672


>UniRef50_Q4T0Y8 Chromosome 12 SCAF10787, whole genome shotgun sequence. (Fragment)
           n=1 Tax=Tetraodon nigroviridis RepID=Q4T0Y8_TETNG
          Length = 809

 Score = 75.7 bits (184), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 54/454 (11%), Positives = 112/454 (24%), Gaps = 93/454 (20%)

Query: 34  CKNALKLPVLEVLPGGGWDNLRNVDMGRVMD-LTYT-NCKTTEDGQYIIPDEVYTIPQKE 91
           C  +   P +E+L G G+D +       V++  ++   C+T   G +     +Y +P   
Sbjct: 101 CTQSTLPPNVELL-GLGFDVVSEQTRASVINTKSFGGQCRTIYSGVH---QTIYRLPVST 156

Query: 92  SNLEMNSEVLESWMNYQST----TSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVT 147
                  +V   + +   +     + SI           G  + +F+  +      + + 
Sbjct: 157 LQYSFMVKVQNDFSDEMFSSKWHYAKSIVQRERASGTTTGYRNYDFRETEDRTRMQKLLV 216

Query: 148 TRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVIT 207
            + ++    +   +     LS    KAL+ +    +             ++  +GTH ++
Sbjct: 217 LKNEIEVAQFQSNSPQYIPLSEELWKALVKLPSVYDYAA-------YRKVLERFGTHYLS 269

Query: 208 SVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYL 267
               G        +        +   +         +  +  F          S    + 
Sbjct: 270 EGSLGGTFKVVAKIDEETQRYMRTESSEYNECEETKYWILF-FSFTRKTCRSGSSNSRFS 328

Query: 268 SNRTN----SRVQSFGGVP-----------FYPGIT---LETWQKGITNHLVAIDRAGL- 308
           +   +    SRV   GG               P         W   + +      +    
Sbjct: 329 TGTRSGNHLSRVDVVGGGVQHSAALSTMSLDDPNKNWEMYSNWADSVRSFPQVTKQKVRE 388

Query: 309 ---------------------------PLHFFIKPDKLPGL--PGPLVKKLSKTVETAVR 339
                                      P    ++   L  L             +  A+ 
Sbjct: 389 TQPNGISKVMLDLPVNVPARLDLENVIPTPACVQLRPLSELVKEVQCAGVKKMYLRRAIE 448

Query: 340 HYYTFNTHPGCTNVDSPNFNFQANMDDD-SCDAKVTNFTFGGVYQECTELSGD------- 391
            Y + +    C     P  N      D  +C       T G   ++ TE+ G        
Sbjct: 449 QYLSESDPCHCQ----PCRNNGLVFTDGNTCKCVCKPGTSGLACEQGTEIEGQQGVIQGS 504

Query: 392 -------VLCQN--------LEQKNLLTGDFSCP 410
                    C                  G   C 
Sbjct: 505 WACWSTWSSCNGARRSRSRSCSNPAPQNGGQYCS 538


>UniRef50_C3ZT46 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
           RepID=C3ZT46_BRAFL
          Length = 776

 Score = 74.5 bits (181), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 31/195 (15%), Positives = 63/195 (32%), Gaps = 24/195 (12%)

Query: 132 EFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMAT 191
           ++      +   Q    + + +  I+     P   LSL F +  + + D  +  + +   
Sbjct: 111 DYSSASRKKNLVQRFC-KNKRKYEIFLDDVRPD-TLSLDFLRDFLALPDSFKTGKQE--- 165

Query: 192 YLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFK 251
              +  I+ YGTH I S   G +      V  +       S    +  A  ++  + +  
Sbjct: 166 --LQKFIIRYGTHYIKSAKFGGSF----RVFKTQEASKTQSLTEFSVEAQASYSGMFSAG 219

Query: 252 VETDYISQTSLTKDYLSNRTNSRVQSFGGV--------PFYPG---ITLETWQKGITNHL 300
                   +   +   S  +N+RV + GG          FY      T   W K I  + 
Sbjct: 220 ASFGMKGSSESAQ--SSKTSNTRVTAEGGHQEVAAVVADFYTTGFKDTFSQWLKTIPTYP 277

Query: 301 VAIDRAGLPLHFFIK 315
             ++     +   + 
Sbjct: 278 KPVEMFMGTITELLN 292


>UniRef50_Q117U3 Membrane attack complex component/perforin/complement C9 n=1
           Tax=Trichodesmium erythraeum IMS101 RepID=Q117U3_TRIEI
          Length = 453

 Score = 74.1 bits (180), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 34/247 (13%), Positives = 67/247 (27%), Gaps = 37/247 (14%)

Query: 85  YTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQ 144
           Y    + +  E    + +S   Y    S++    +       G+    F        K  
Sbjct: 47  YVDLLRATTYESEVIIGKSMQEYIKKLSINAGISVGY--AFLGEIENRFDMSDDKSSKRT 104

Query: 145 AVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTH 204
                  + N +Y +       LS  F + L  +               A  L   YGTH
Sbjct: 105 NEYISYDINNTLYRITLKGNVPLSEQFQEDLNSL--------------DATTLFEKYGTH 150

Query: 205 VITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTK 264
            + S   G  +     + +  + D+   +        +      N+   +D         
Sbjct: 151 YLKSTWIGGRISFSTTIDTYGMTDDMRKKFAFVTKRKVG-----NWTGTSDVELTREEKD 205

Query: 265 DYLSNRTNSRVQSFGGVP------------FYPGITLETWQKGITNHLVAIDRA----GL 308
                ++NS V+ +GG P                   + W + +       D       +
Sbjct: 206 ISEKMKSNSIVRVWGGDPKLGRDIERAIQGHTVSDIYQQWGQTVEERPYISDFDHGQGLV 265

Query: 309 PLHFFIK 315
           P++    
Sbjct: 266 PIYELAT 272


>UniRef50_Q6TNF0 Complement component C9 n=3 Tax=Clupeocephala RepID=Q6TNF0_CTEID
          Length = 650

 Score = 72.6 bits (176), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 38/296 (12%), Positives = 82/296 (27%), Gaps = 46/296 (15%)

Query: 117 TELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT-SELSLGFTKAL 175
              ++      + +   +++  +    +    RV+ R  + T +      E+S  F   +
Sbjct: 314 ISGSVEFDTKTEKNNIIKQLSEITTTKRKTFMRVKGRVELATYRMRQRGLEVSSTFLDDV 373

Query: 176 MDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT 235
             +    EK       Y A   + +YGTH   +  +G        +    L   + +++T
Sbjct: 374 DALPLTYEK-----GQYFA--FLEDYGTHFTKNGKSGGEYELIYVMNEDILKQKKVTEST 426

Query: 236 VTASAGIAFLNIVNFK------------VETDYISQTSLTKDYLSNRTNSRVQSFGGVPF 283
           +     +     + F                D I+             +  + +  G   
Sbjct: 427 IKDCVEVGIKGSIQFSKIAEAERHVKPVGNCDTITDKPTDDRDTRGVIDKVLIAVRGGSP 486

Query: 284 YPGITLE---------------TWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK 328
              + ++                W K ++     I     P++  I       L  P  +
Sbjct: 487 ATAVAMKSQLTKDGILDYTQYVEWAKTVSALPALIHSDPEPIYNAI------PLDFPDAQ 540

Query: 329 KLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMD-DDSCDAKVTNFTFGGVYQ 383
                +  A+  Y    +   C     P  N    +  D  C       + G   Q
Sbjct: 541 PRRDNLRRAIDDYVAEYSVCKCQ----PCQNGGTVIQIDGECKCMCLPGSEGVACQ 592


>UniRef50_D2I7R7 Putative uncharacterized protein (Fragment) n=2 Tax=Amniota
           RepID=D2I7R7_AILME
          Length = 438

 Score = 72.6 bits (176), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 42/299 (14%), Positives = 85/299 (28%), Gaps = 48/299 (16%)

Query: 50  GWDNLRNVDMGRVMDLTYTNCKTTE----DGQYIIPDEVYTI-PQKESNLEMNSEVLESW 104
           G +   N   G V+D  Y     +     + ++  P  V +  PQ +   E      ES+
Sbjct: 148 GINLFTNRFEGPVLDHRYYAGGCSPHYILNTRFRKPYNVDSYDPQTQGKYEFALTEYESY 207

Query: 105 MNYQSTTS---LSINTELALFSRVNGKFSTEF--------QRMKTLQVKDQAVTTRVQVR 153
            +++   +    S++       ++ G F   F        Q +   +      +T +  R
Sbjct: 208 SDFEHNVTETRASVS-SFGFGFKIPGIFELGFNTASGNGKQFISRTKRFSHTKSTFLHAR 266

Query: 154 NRIYTVKTTPTS---ELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVD 210
           + +   +         L   F + +  +  +    + +        L  ++GTH IT   
Sbjct: 267 SDLEIARYKLKPRSLMLHYEFLQRVKALPLEYSYGEYRD-------LFRDFGTHYITEAV 319

Query: 211 AGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFL-----NIVNFKVETDYISQTSLTK- 264
            G        +    +     S   V A A   F       +V  K+         +   
Sbjct: 320 LGGVYEYTLVMNKEAMERADYSLKDVRACAQNGFRIGIGIEVVYVKLGVSVDICRGILNE 379

Query: 265 ----DYLSNRTNSRVQSFGGVPFY----------PGITL-ETWQKGITNHLVAIDRAGL 308
               +  +   +  V    G              P   L + W   +  +   I     
Sbjct: 380 IGDRNKRNTMVDDLVVLVRGGASEHITTLAYKELPTADLMQEWGDAVQYNPDIIKIKVQ 438


>UniRef50_C3Z0X4 Putative uncharacterized protein n=2 Tax=Branchiostoma floridae
           RepID=C3Z0X4_BRAFL
          Length = 1339

 Score = 71.8 bits (174), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 49/375 (13%), Positives = 96/375 (25%), Gaps = 96/375 (25%)

Query: 58  DMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINT 117
             G  +   Y     + D    +PD +      +    + S    S   Y+   +     
Sbjct: 197 PPGWEIRHKYKYKDDSYDRN-EVPDSMTVQGIYD--TNVGSYTFSSTEEYRQYLAEKSAV 253

Query: 118 ------------ELALFSRVNGKFSTEFQRMKTLQVKD---------------------- 143
                       + +    V G F   F        +                       
Sbjct: 254 TSAKAMFQEEINKASGHVAVGGLFGIGFSVGGGKSSQSGTSSQSSDSSASSSASAQLSEQ 313

Query: 144 --QAVTTRVQVRNRIYTVKTTPTSE--LSLGFTKALMDICDQLEKNQTKMATYLAELLIL 199
             Q     +++    Y +     +   L++GF +  + + +         A  + +   L
Sbjct: 314 HAQTYMAMLEINIFRYEIFMDDVTPDRLNVGFLRDFISLPESYFSPG---AEIIFQNFYL 370

Query: 200 NYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVN---------- 249
            +GTH I S   G  L     +  +       S +     A   +   ++          
Sbjct: 371 RWGTHYIKSAKFGGQL----KIIKTKQATKDLSMSEFATRAEADWKMTMSTFSALASQTK 426

Query: 250 ----------------FKVETDYISQTS-----LTKDYLSNRTNSRVQSFGG-------- 280
                            K +    S +        +      +N  ++  GG        
Sbjct: 427 SSSWLDEDETKTESKEAKGQAASDSDSQANREQQKQASSQEYSNEVLEVQGGDQQIAAAI 486

Query: 281 -VPFYPGIT--LETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLV------KKLS 331
              +   +T  L+ W + I ++         P+   +    +   P   V      K+  
Sbjct: 487 TEMYTTALTTELKDWLESINDYPKPFSFVLRPVPDLLNIPFVTLFPAGDVDYGCFGKRDL 546

Query: 332 KTVETAVRHYYTFNT 346
           KT E   R YYT  T
Sbjct: 547 KTEEGTGRKYYTHTT 561


>UniRef50_C3ZXW6 Putative uncharacterized protein n=2 Tax=Branchiostoma floridae
           RepID=C3ZXW6_BRAFL
          Length = 1244

 Score = 71.8 bits (174), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 39/250 (15%), Positives = 71/250 (28%), Gaps = 47/250 (18%)

Query: 137 KTLQVKDQAVTTRVQVRNRIYTVKTTPTSE--LSLGFTKALMDICDQLEKNQTKMATYLA 194
           K    + Q+  + +Q     Y +     +   LSL F +  + +     + + K      
Sbjct: 325 KESSSQKQSFMSLIQCDVIRYEIFLDEITPDTLSLPFLRDFLALPKNFIEGKAK-----L 379

Query: 195 ELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVET 254
           +  I+ YGTH I S   G +      +  +       S    +  A  ++ ++  F    
Sbjct: 380 QRFIIRYGTHFIKSAKFGGSF----RLFKTQEASKSESMEDFSIQAQASYNSLF-FNAGG 434

Query: 255 DYISQTSLTKDYLSNRTNSRVQSFGGV--------PFYPG---ITLETWQKGITNHLVAI 303
            +    S      S  +N+ V   GG          FY      T   W K I  +   I
Sbjct: 435 HFGMGMSSGSSQSSKTSNTHVTVEGGDQEVASIVADFYSTGFKDTFVEWLKSIPAYPKPI 494

Query: 304 DRAGLPLHFFIKPDK---LP---------------------GLPGPLVKKLSKTVETAVR 339
           +     +   +  +     P                           + K    +E A+ 
Sbjct: 495 EMFMGTMSELLDMNYKLLFPFDISDAADGCFSEKYCDFTSVDKFQEGLDKKRLALERAIV 554

Query: 340 HYYTFNTHPG 349
            Y      P 
Sbjct: 555 MYMEEGPVPT 564


>UniRef50_UPI0000F2BC28 PREDICTED: similar to complement component C8 beta subunit n=1
           Tax=Monodelphis domestica RepID=UPI0000F2BC28
          Length = 631

 Score = 71.8 bits (174), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 52/424 (12%), Positives = 113/424 (26%), Gaps = 68/424 (16%)

Query: 32  QICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTY--TNCK--TTEDGQYIIPDEVYTI 87
           ++C+ +            G +   N   G V D  Y   NC     +  +Y +P  +   
Sbjct: 201 KLCQGSKNQYWGTGSLASGINIFTNALEGVVFDNNYYGGNCNAFVIDQDKYRLPSNLERY 260

Query: 88  PQK-ESNLEMNSEVLESWMNYQSTT------SLSINTELALFSRVNGKFSTEFQRMKT-- 138
             +     E   +  ES+  ++ +          +  +L + + ++  ++ E Q ++   
Sbjct: 261 SIEVRGYYEFVYKEYESYAAFERSVIREGMKDKKMGPDLHILNWIDIGYNFESQSLRRFL 320

Query: 139 ----LQVKDQAVTTRVQVRNRIYTVKTTPTS-ELSLGFTKALMDICDQLEKNQTKMATYL 193
                  + ++    VQ    I   K           F   +  +        +  +   
Sbjct: 321 SKIRRATQSKSKILHVQCTIDIGRYKMKSKLLMFDYEFLMRVGRLP-------SDYSYGE 373

Query: 194 AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFK-- 251
               I  YGTH+I+    G        +    +     + + + +    A+ +       
Sbjct: 374 YRDFIRAYGTHIISDAIIGGVYEYALILNPDGMDSEGYTFDDIKSCTQEAYHSSDITNRD 433

Query: 252 -----------------VETDYISQT----SLTKDYLSNRTNSRVQSFGGVPFYPGITLE 290
                                   +          +L   T   + S           +E
Sbjct: 434 FVGMRMDQRCHVLLDQIANLGKTEEDVPIVEDLAVFLRGGTIPSITSLAYKRLPNKELME 493

Query: 291 TWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGC 350
            W          +    +P+H                  L   + +AV+ YY       C
Sbjct: 494 KWGDAAKLFPEVLKIKVIPMHEMWTGQNF-----INRLHLKNNMRSAVKEYYEETHVCHC 548

Query: 351 TNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCP 410
                  F     + D  C+              C   +  + C+    +   TG +SC 
Sbjct: 549 APCLGNGFPI---IRDSYCEC------------LCGMGTCGISCELGTSEGDATGSWSCW 593

Query: 411 PGYS 414
             ++
Sbjct: 594 TSWT 597


>UniRef50_C3XW28 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
           RepID=C3XW28_BRAFL
          Length = 1503

 Score = 69.5 bits (168), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 37/180 (20%), Positives = 60/180 (33%), Gaps = 16/180 (8%)

Query: 62  VMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL 121
           V+     N  T  D    +PD +      +   E+ S V ES  +Y+    +        
Sbjct: 339 VVQRNCKNLATYHDED--VPDNMNVHGIFD--TEVASFVFESRESYRHYIQMKAGMS--- 391

Query: 122 FSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSE--LSLGFTKALMDIC 179
           FS    K + +        V  Q   + +Q     Y +     S   LSL F +  + + 
Sbjct: 392 FSSFVFKAAVDTVYGSKTSVSKQQFMSLIQCNVVRYEIFLDEISPDTLSLAFLRDFLSLP 451

Query: 180 DQLEKNQTKMATYLAELLILNYGTHVITSVDAGA--ALVQEDHVRSSFLLDNQNSQNTVT 237
                    M     +  IL YGTH I S   G    L +      + +     S+ +V+
Sbjct: 452 FNFV-----MGKAKLQKFILRYGTHFIKSAKFGGSFRLFKTQEASKAAVDTVYGSKTSVS 506



 Score = 65.7 bits (158), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 45/271 (16%), Positives = 67/271 (24%), Gaps = 38/271 (14%)

Query: 112 SLSINTELALFSRVNGK-FSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSE--LS 168
           S        LF        + +        V  Q   + +Q     Y +     S   LS
Sbjct: 475 SAKFGGSFRLFKTQEASKAAVDTVYGSKTSVSKQQFMSLIQCNVVRYEIFLDEISPDTLS 534

Query: 169 LGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLD 228
           L F +  + +          M     +  IL YGTH I S   G +        +S +  
Sbjct: 535 LAFLRDFLSLPFNFV-----MGKAKLQKFILRYGTHFIKSAKFGGSFRLFKTQEASKVSS 589

Query: 229 NQNSQNTVTASAGIAFLN-IVNFKVETDYISQTSLTKDYLSNRTN---SRVQSFGGVPFY 284
            Q       AS    F N    F +E+   S  S                V S     + 
Sbjct: 590 FQEFSEKSEASLNAIFANAKAEFGLESSSGSSQSSKTSGTHVTVEGGDQEVASIVADFYS 649

Query: 285 PGI--TLETWQKGITNHLVAIDRAGLPLHFFIKPDK---LP------------------- 320
                T   W K I      I+     +   +  +     P                   
Sbjct: 650 TSFKDTFAEWLKSIPKFPKPIEMFMGTMSELLDMNYKLLFPFDIKDAADGCFSKTYCEFT 709

Query: 321 --GLPGPLVKKLSKTVETAVRHYYTFNTHPG 349
                   + K    +E A+  Y      P 
Sbjct: 710 SAEKFEEAMDKKRLALERAIAVYMEEGPVPT 740


>UniRef50_C2FV94 Putative uncharacterized protein (Fragment) n=1
           Tax=Sphingobacterium spiritivorum ATCC 33300
           RepID=C2FV94_9SPHI
          Length = 308

 Score = 68.7 bits (166), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 50/329 (15%), Positives = 104/329 (31%), Gaps = 45/329 (13%)

Query: 3   SFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRV 62
           + +  ++   ++        + +       + K A  +     L G G+D       GR 
Sbjct: 5   NLIYTLIASTLLLTNCKKNEITQEKLPNNNLEKQASSMDNKLDLLGYGYDA-----TGRY 59

Query: 63  MDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALF 122
            ++  +  +  +  ++   D  +             +   +   Y  + S+      + F
Sbjct: 60  ANIESSRLQVIDAEKFYNLDRSHVGIIAGVEDFFEYKFANNAREYSDSLSVKATGGFSAF 119

Query: 123 SRVNGKFSTEF---QRMKTLQVKDQAVTTRVQVRNRIY-TVKTTPTSELSLGFTKALMDI 178
                + +T F   +  K       A    VQ R     +++    + LS  F   L  +
Sbjct: 120 GLFKAEINTSFGNSEAFKGSYSLANATKYIVQKRLNFSTSIQNLRDNYLSASFVNDLNRL 179

Query: 179 CDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTA 238
                          A+ ++  YGTHV T++  GA          S+  +  +S+   + 
Sbjct: 180 S--------------AQEIVSYYGTHVCTNIVLGA------KFSFSYRTETSSSKKRESL 219

Query: 239 SAGIAFLNIVNF-KVETDYISQTSLTKDYLSNRTNSRVQSFGGV-----------PFYPG 286
           +AG+A   +        D+    S  K   + + N R     G                 
Sbjct: 220 AAGLAVNGLAKVWSATADFTYNASDAKANYNQQVNYRSVGGDGTQGLIGEISLDYSTPTK 279

Query: 287 ITLETWQKGI-TNHLVAIDR---AGLPLH 311
           I++  WQ      + + ID      +PL+
Sbjct: 280 ISINQWQSTCKPQNAILIDFGNGGLVPLY 308


>UniRef50_A7SG86 Predicted protein n=3 Tax=Nematostella vectensis RepID=A7SG86_NEMVE
          Length = 483

 Score = 68.7 bits (166), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 31/253 (12%), Positives = 64/253 (25%), Gaps = 19/253 (7%)

Query: 100 VLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTV 159
             E      +  + ++     L      K S +          +    T V+V +   + 
Sbjct: 76  YFEDTRQMYNFLNSNVKIGADLAGTFTFKTSLDAVTNSMTATNESIKGTVVRVSDYSMSQ 135

Query: 160 KTTPTS----ELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAAL 215
                     +    F      +  ++ + +   +       I  YGTH++T V  GA++
Sbjct: 136 TLAKDCLNEIDFKEKFINDFKKLPSEISRPEDSWSWKDYSHFIKTYGTHIVTGVTYGASI 195

Query: 216 VQEDHVRSSFLLDNQNSQNTVTASAG-----IAFLNIVNFKVETDYISQTSLTKDYLSNR 270
                   S     +     + A               N  V       T  T       
Sbjct: 196 -YSYAFSRSDTHYTKED-FKIQACLSLLGPAALKYLKGNLNVSVCSGVNTKDTDRISRFH 253

Query: 271 TNSRVQSFGGVPF--------YPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL 322
            N++V   GG                +E + K        +  +   +   +        
Sbjct: 254 MNNKVVIRGGKAETRAKLLYKREPELVEQFLKEGRETPSPVQYSFTSIWDALSSRFYATE 313

Query: 323 PGPLVKKLSKTVE 335
               V+ L +  +
Sbjct: 314 YYAKVRNLEQFFK 326


>UniRef50_A8GEE9 Membrane attack complex component/perforin/complement C9 n=1
           Tax=Serratia proteamaculans 568 RepID=A8GEE9_SERP5
          Length = 489

 Score = 68.7 bits (166), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 61/408 (14%), Positives = 117/408 (28%), Gaps = 63/408 (15%)

Query: 22  PLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTN-CKTTEDGQ-YI 79
           P       G   C     L   +           +  +  ++D + +   + T +GQ Y 
Sbjct: 25  PSDTLPGVGIIGCGYNPFLAYADA----------SAVLHPILDWSKSQFNEITMNGQQYQ 74

Query: 80  IPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTL 139
           +PD +  +    SN    S   +S  +Y +  + SI              S   +   + 
Sbjct: 75  LPDVLQAVWL--SNQSYASVTGKSLQSYLTELANSIKVSGNYGF---FSASATNEFSDSS 129

Query: 140 QVKDQAVTTRVQVRNRIYTVKTTPTSE-----LSLGFTKALMDICDQLEKNQTKMATYLA 194
             K +   +R Q    ++++            +S  F K +  I           +    
Sbjct: 130 LRKSENEFSRCQQSFDLWSISIPADIARLQNYVSDDFIKLINAINP--------ESKDSI 181

Query: 195 ELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVET 254
             +   YG+HV+ S   G       HV +S        +  ++      +  + + ++  
Sbjct: 182 ATVFNVYGSHVLMSGVMGGKA----HVSASANKLTLTQKFEMSTIVQAKYEQLTS-QLSV 236

Query: 255 DYISQTSLTKDYLSNRTNSRVQSFGGVPF------------YPGITLETWQKGITNHLVA 302
           +   + S   D  S   +      GG P                  L+ W + I++  V 
Sbjct: 237 EDKLKYSEAFDSFSESGSYTYDILGGSPSLGALVFKNNSQGSSDDNLKNWIQSISSMPVL 296

Query: 303 IDR----AGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNF 358
                  + +P+    +                   + AV      N     T V   N 
Sbjct: 297 TKFIDQTSLMPVWLLCEDKTKADALKKYYDNTWSKSQMAVAS-LRANYIDELTFVLGDNS 355

Query: 359 NFQANMDDDSCDAKV-TNFTFGGVYQECTELSGDVLCQNLEQKNLLTG 405
           +  A +        +  N   GG Y          LC +  Q   + G
Sbjct: 356 DIPAPV--GYTKVPIDLNSDAGGKYV--------YLCYHEAQFTPVNG 393


>UniRef50_Q64VU4 Putative uncharacterized protein n=2 Tax=Bacteroides fragilis
           RepID=Q64VU4_BACFR
          Length = 372

 Score = 68.0 bits (164), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 45/296 (15%), Positives = 90/296 (30%), Gaps = 66/296 (22%)

Query: 103 SWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTT 162
           +  +Y    +  +    AL        S+             A  T    R R++   +T
Sbjct: 99  TAQDYTRNVTSKVKLGGALSLFSGSLSSSFSSTQHYTSKYSIADYTSFIRRRRLFLTAST 158

Query: 163 PTSE--LSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDH 220
                 L+  F   L                     +I +YGTHV+T +  G  +     
Sbjct: 159 ELLSKYLTKMFVDDLSKQSPSF--------------IIQHYGTHVLTDITLGGRI---TV 201

Query: 221 VRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG 280
           +  S +  ++ +       A     N+ N  V+  Y  QT +  +          ++ GG
Sbjct: 202 LYRSSINTSKKTATVEAGCASG-IKNMFNLSVDGHYD-QTLVKDNSEQEIVY---RTEGG 256

Query: 281 VPFY-------------PGITLETWQKGITNHLV----AIDRAGLPLHFFIKPDKLPGLP 323
            P                 I + +WQ+   ++ +    A   + +P++  +         
Sbjct: 257 DPSRALIGQLNYDSKNPSVIDISSWQQSCDDNNMTLVDAEPGSLIPIYDLVSDMGKKEQ- 315

Query: 324 GPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFG 379
                     ++ AV +Y   +++               ++DD S    V N + G
Sbjct: 316 ----------LKLAVENYLKEHSY--------------VDIDDSSKGGAVRNNSRG 347


>UniRef50_C3ZSP3 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZSP3_BRAFL
          Length = 992

 Score = 67.6 bits (163), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 53/361 (14%), Positives = 101/361 (27%), Gaps = 60/361 (16%)

Query: 138 TLQVKDQAVTTRVQVRNRIYTVKTTPTSE--LSLGFTKALMDICDQLEKNQTKMATYLAE 195
           +   + Q   + ++     Y +     +   LSL F +  + +     + + K      +
Sbjct: 251 SSSSEKQKFMSLIKCDVIRYEIFLDEVTPDSLSLAFLRDFLSLPKNFIQGKAK-----LQ 305

Query: 196 LLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETD 255
             I+ YGTH I S   G +      +  +       S    +  +  ++ ++  F     
Sbjct: 306 DFIIRYGTHFIKSAKFGGSF----KLFQTQEATKTESLEDFSVQSEASYSSLF-FSGGGH 360

Query: 256 YISQTSLTKDYLSNRTNSRVQSFGGV--------PFYPG---ITLETWQKGITNHLVAID 304
           Y ++ S      S  +++ +   GG          FY      T   W K + ++   I+
Sbjct: 361 YSNEESSGNTASSQTSSTHLMIEGGDQEVAAIVADFYTTSFKETFTEWLKSVPSYPKPIE 420

Query: 305 ------------RAGLPLHFFIKPDKLP------------GLPGPLVKKLSKTVETAVRH 340
                          L   F I                        + K    +E A+  
Sbjct: 421 MFMGTMSELLNLNFKLLFPFDISDAADGCFSKKYCDVSSIEQFQKSMDKKRLALERAIAV 480

Query: 341 YYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFG--GVYQEC--TELSGDVLCQN 396
           Y      P          +F        C  +      G  G  Q      ++GD     
Sbjct: 481 YMEEGPIPTT--------DFHLQGGKPGCQTEALTVKGGEKGASQPSWLELINGDTYKYL 532

Query: 397 LEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAE 456
            E  N   G       Y      SQ++    + +  +  CT+K       +      K  
Sbjct: 533 GELPNDYVGMIVGRAEYISPLEHSQSNSVALASI-VQAPCTVKWSNSYQIKPAEEGGKCL 591

Query: 457 F 457
           +
Sbjct: 592 Y 592


>UniRef50_UPI000155C7F4 PREDICTED: similar to complement component 9 n=1
           Tax=Ornithorhynchus anatinus RepID=UPI000155C7F4
          Length = 430

 Score = 66.8 bits (161), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 41/300 (13%), Positives = 73/300 (24%), Gaps = 52/300 (17%)

Query: 113 LSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFT 172
             + + +          +      K  +     V   VQ+      +  +    L+  F 
Sbjct: 34  SELQSNMVFRFSKAKSINKINSYSKDTKKSFLHVKGEVQLGRF---LMRSRDVMLTTTFL 90

Query: 173 KALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNS 232
             L  +    E     M  Y A   +  YGTH  +S + G A      +    +      
Sbjct: 91  DDLKALPLDYE-----MGEYFA--FLETYGTHFSSSGNLGGAYELIYVLDDIAMKKQGFE 143

Query: 233 QNTVTASAGIAFLNIVNFKVE-----TDYISQTSLT--------KDYLSNRTNSRVQSF- 278
            N V    G  F   +                + +T             N     +    
Sbjct: 144 VNDVQRCLGFNFGITLKVSDSEVKPEFTSSRCSQITVKHGDGRRSGINHNNVIDDIIVMI 203

Query: 279 -GGVPFY------------PGITLE---TWQKGITNHLVAIDRAGLPLHFFIKPDKLPGL 322
            GG                  +       W   + +  V I +   P++  +        
Sbjct: 204 KGGTIEQAAKLREKLMRGATAVDASYFVDWAASLQDAPVLIHQKPSPIYNLVPVKM---- 259

Query: 323 PGPLVKKLSKTVETAVRHYY-TFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGV 381
                +   K +E A+  Y   FN    C               + +C   +    F GV
Sbjct: 260 --KDAQIRKKNLERAIEDYIVEFNVCK-C-QPCQNGGTVMLVDGECTCSCSLH---FEGV 312


>UniRef50_C8V7Z0 SpoC1-C1C protein [Source:UniProtKB/TrEMBL;Acc:Q00785] n=3
           Tax=Emericella nidulans RepID=C8V7Z0_EMENI
          Length = 456

 Score = 66.4 bits (160), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 63/405 (15%), Positives = 132/405 (32%), Gaps = 70/405 (17%)

Query: 42  VLEVLPGGGW----DNLRNVDMGRVMDLTYTNCKTT---EDGQYIIPDEVYTIPQKESNL 94
            + + PG       + L  V+  ++++    N  TT    + QY++P++V+ +P   +  
Sbjct: 17  GITLFPGSNLFDYLEILGGVEKVQLLNFNLNNKPTTVPGSNKQYLVPEDVFILP---AGT 73

Query: 95  EMNSE--VLESWMNYQSTTSLSINTELALFSRV---NGKFSTEFQRMKTLQVKDQAVTTR 149
           E+ +E  +  +     +  +++ +     F      NGK              D+ +   
Sbjct: 74  EIIAENLLCTTGAALANELAINPSMAYRYFGISAERNGKIGYRVSFN------DRYLFGL 127

Query: 150 VQVRNRIYTVKTTPTSE---LSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVI 206
             + +  YTV+    S    ++  F  A   +    E +    A          +GTHV 
Sbjct: 128 WSIGDLNYTVQFDMQSLERCINADFIWAARRLPCWDEND--ASARDAFAKFFATWGTHVT 185

Query: 207 TSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDY 266
           T    GA       ++ +    +  S+          + +++           T+  ++Y
Sbjct: 186 TGCCLGAR----YQLQVTRPDASDESKKNFHEHIETEYSSVLGINGG---TRDTAQYREY 238

Query: 267 LSNRTNSRVQSFGGVPF-------YPGIT--LETWQKGI--TNHLVAIDRAGLPLHFFIK 315
           L  R  S+    GG P         P  +     W + I  +     I      ++ F+ 
Sbjct: 239 LGRR-ESKCSVMGGHPQLKRSLSRDPTNSRLFSQWIRSIGASGTQDVIHVLADSIYNFLL 297

Query: 316 PDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPG----------------CTNVDSPNFN 359
                  P P  K++   ++ A R +  F T  G                C    +P  +
Sbjct: 298 RS-----PNPEHKEIGDKIQRASRFHSKFITATGVFKVKGIGGATGRVSSCEVRGAPGIS 352

Query: 360 FQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLT 404
            Q      +  + ++   F    +       ++ C  +     LT
Sbjct: 353 LQVIPRRGTAASSLSKIKF----EALQLSGDEIECDVIMSAPPLT 393


>UniRef50_C3YP09 Putative uncharacterized protein n=8 Tax=Deuterostomia
            RepID=C3YP09_BRAFL
          Length = 2374

 Score = 65.7 bits (158), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 42/257 (16%), Positives = 83/257 (32%), Gaps = 47/257 (18%)

Query: 131  TEFQRMKTLQVKDQAVTTRVQVRNRIYT--VKTTPTSELSLGFTKALMDICDQLEKNQTK 188
              +  ++       AVT         Y   +      +L+L F +  + + +        
Sbjct: 799  YRYVFLRLQVSLTPAVTGESFTCGHRYEIFLDFVNPEDLNLAFMRDFLSLPNSYFSVG-- 856

Query: 189  MATYLAELLILNYGTHVITSVDAGAAL-VQEDHVRSSFLLDNQNSQN------------- 234
             A    +  I  +GTH ITS   G  L + +    +  + +   SQ              
Sbjct: 857  -ADREYQWFIQRWGTHYITSAKFGGQLKIIKTKEITEEVSEESFSQAAQSDFKKLLSTYS 915

Query: 235  -TVTASAGIAFLN-------IVNFKVETDYISQTSLTKDYLSNR-----TNSRVQSFGG- 280
               T +   ++ +         +   E    + +  + + L++R     +N  +++ GG 
Sbjct: 916  AQQTQTKSSSWFHSHETKNERQSASGEQSQDTTSETSTEELASRNRMEFSNEVLKAQGGS 975

Query: 281  -------VPFYP---GITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKK- 329
                     FY    G  L+ W + I     A +    PL   +  +     P  +    
Sbjct: 976  QRISAAITEFYTTSFGNLLKEWLESINEFPKAFEFTMQPLPDLLNMNLDSLFPSGITDYG 1035

Query: 330  ---LSKTVETAVRHYYT 343
                S + ++A R YYT
Sbjct: 1036 CFGSSLSTDSAGRRYYT 1052


>UniRef50_C3ZTY9 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZTY9_BRAFL
          Length = 1337

 Score = 65.7 bits (158), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 36/203 (17%), Positives = 68/203 (33%), Gaps = 36/203 (17%)

Query: 113 LSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFT 172
            S+N             S++F++   + + +  V     +R  I+  + TP   LSL F 
Sbjct: 307 ASVNAAWGG--------SSKFEKQMFMSLIETDV-----IRYEIFLDEITPD-SLSLSFL 352

Query: 173 KALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNS 232
           +  + +       + K      +  I+ YGTH I S   G +      +  +       S
Sbjct: 353 RDFLSLPKNFILGKAK-----LQDFIIRYGTHFIKSAKFGGSF----RLFKTQEAAKSES 403

Query: 233 QNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGV--------PFY 284
             + + SA  ++  + +         ++       S  T+  +   GG          FY
Sbjct: 404 LTSFSVSAQASYSGMFSAGGHYGRNEESGSASSSKSASTH--IVVEGGDQKVASIVADFY 461

Query: 285 PG---ITLETWQKGITNHLVAID 304
                 T   W K I ++   I 
Sbjct: 462 TTSFKDTFTEWLKSIPSYPKPIQ 484


>UniRef50_Q5W9E8 Pleurotolysin B n=3 Tax=Agaricales RepID=Q5W9E8_PLEOS
          Length = 523

 Score = 65.7 bits (158), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 45/257 (17%), Positives = 74/257 (28%), Gaps = 21/257 (8%)

Query: 52  DNLRNVDMGRVMDLTYTNCKTTEDGQYII-PDEVYTIPQKESNLEMN---SEVLESWMNY 107
           DN  N+  G +M             + I+ PD +  I    + +E     +E  E+ M  
Sbjct: 71  DN--NLLKGIIMGRD---GPVPSSRELIVRPDTLRAIINNRATIETTTMEAEFTETLME- 124

Query: 108 QSTTSLSINTELALFSRVN-GKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTV---KTTP 163
            +  S S+       +  +    S+ F+  +T +    +           +T        
Sbjct: 125 SNYNSASVKVSAPFITANSEYSESSSFKNTETEKSMYTSSRYLFPQGRIDFTTPDSGFDD 184

Query: 164 TSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVI-TSVDAGAALVQEDHVR 222
             +LS  FT  +      L K          + L   YG HV  T V  G  L       
Sbjct: 185 VIKLSPQFTSGVQAA---LAKATGTEKREALQNLFQEYG-HVFRTKVHIGGVLSAHTMET 240

Query: 223 SSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVP 282
            S   +    +  V A    A              +Q ++T     NR  +      G  
Sbjct: 241 FSRSENETEVKQDVKAGLEGAVKGWGGGATAGHGNTQGTITT--SQNRKLNVKYIVNGGD 298

Query: 283 FYPGITLETWQKGITNH 299
           +      E W       
Sbjct: 299 YTKIQNTEEWVASTNQS 315


>UniRef50_A3XM68 Guanosine polyphosphate pyrophosphohydrolase/synthetase-like
           protein n=1 Tax=Leeuwenhoekiella blandensis MED217
           RepID=A3XM68_9FLAO
          Length = 1098

 Score = 65.7 bits (158), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 36/249 (14%), Positives = 83/249 (33%), Gaps = 34/249 (13%)

Query: 95  EMNSEVLESWMNYQST-TSLSI-NTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQV 152
           E+  E +++  +++ T  S       ++       K + + ++                +
Sbjct: 50  ELRFEFIQTAHDFEHTILSTQAEGLPVSAHFSQAYKGTADAEKNNKQLYVY-------TL 102

Query: 153 RNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAG 212
           R +    K  P   LS GF  A+M +   +           AE  +  +GTH  T V  G
Sbjct: 103 RKKALFAKKLPKIALSEGFKDAVMRLGRDVT----------AEGFLSWFGTHYTTEVTYG 152

Query: 213 AALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTN 272
              +  + + S+  +++ +S+                 ++      +  +  D       
Sbjct: 153 GFFLTRNSINSTDFINSPHSEEVFKT----------KLRIAIGEQQRGEVLTDPYIPLGE 202

Query: 273 SRVQSFGGVPFYPGITLETWQKGI-TNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLS 331
            +  + GG P       + W++ +   + V I      L   +     P +    ++K  
Sbjct: 203 PQRFTRGGNP--NEFWDKRWEQTLNPKNAVIIAAQYAELSELLTVQNFPEIE--DLQKKK 258

Query: 332 KTVETAVRH 340
             ++ A+ H
Sbjct: 259 ALLQKAIDH 267


>UniRef50_C3YVU9 Putative uncharacterized protein n=2 Tax=Branchiostoma floridae
           RepID=C3YVU9_BRAFL
          Length = 1490

 Score = 65.7 bits (158), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 49/364 (13%), Positives = 94/364 (25%), Gaps = 91/364 (25%)

Query: 62  VMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTT---SLSINTE 118
           ++  + +N +T  + +  +PD +      ++ +E  S    S   Y+      S   + +
Sbjct: 252 IIQRSCSNLQTYGENE--VPDTMTIQGIYDTKVE--SYTFSSTEEYRQYLAEKSAVTSAK 307

Query: 119 LALFSRVN------------------------------------GKFSTEFQRMKTLQVK 142
                 +N                                       S   Q  +     
Sbjct: 308 AMFQEEINKASGHGAGGGPFGFLFSVGGGKSSQSGTSSQSSGFTAASSARAQLSEQQTQT 367

Query: 143 DQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYG 202
             A+      R  I+    TP  +L++GF +  + +           A  + +   L +G
Sbjct: 368 FMAMLEMDIFRYEIFMDDVTPD-QLNVGFLRDFISLPKSYFSPG---AEIIFQNFYLRWG 423

Query: 203 THVITSVDAGAALVQEDH------VRSSFLLDNQNSQNTV---TASAGIAFLNIVN---- 249
           TH I S   G  L           +  S       +   +   T SA  +     +    
Sbjct: 424 THYIKSAKFGGQLKIIKTKQATKDLSMSEFATRAEADWKMTMSTFSAQASQTKSSSWWHE 483

Query: 250 --------------FKVETDYISQTSLTKDYLSNRTNSRVQSFGG---------VPFYPG 286
                                 +     K      +N  +   GG           +   
Sbjct: 484 HETKSESKQATGQAASGSESQTNNRQEEKISSQEYSNEMLVVQGGDQQIAAAITEMYTTS 543

Query: 287 IT--LETWQKGITNHLVAIDRAGLPLHFFIK---PDKLPGLPGP---LVKKLSKTVETAV 338
           +T  L+ W + I ++          +   +        P        L K   KT +   
Sbjct: 544 LTTELKDWLESIKDYPKPFSFVLRRVTDVLNVPFDSLFPAGEVDYGCLGKTHLKTEKETG 603

Query: 339 RHYY 342
           R YY
Sbjct: 604 RRYY 607


>UniRef50_UPI0000E466A5 PREDICTED: similar to apextrin n=2 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E466A5
          Length = 422

 Score = 65.3 bits (157), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 21/135 (15%), Positives = 43/135 (31%), Gaps = 11/135 (8%)

Query: 40  LPVLEVLPGGGWDNLRNVDMGRVMDL-----TYTNCKTTEDGQYIIPDEVYTIPQKESNL 94
             +++  P GG  N   VD G ++       TY   K T D    IPDEV  + Q+    
Sbjct: 44  YNIIDGNPEGGDLNTGGVDPGLLLSRKIFKLTYDEGKKTFDQSSRIPDEVSYLKQQSPYS 103

Query: 95  EMNSEVLESWMNYQSTTSLSINTELALFSR-----VNGKFSTEFQRMKTLQVKDQAVTTR 149
           + +        +Y +  +  +    ++ +       +   S + +   +           
Sbjct: 104 KSSLSTFFGTKSYAAKLAAQVEVSGSIQASGVYDGFSASVSVDMESFNSAMDS-GTKFGS 162

Query: 150 VQVRNRIYTVKTTPT 164
              +  I +      
Sbjct: 163 SYSKYAIGSQDLNEP 177


>UniRef50_C1MJU5 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MJU5_9CHLO
          Length = 445

 Score = 65.3 bits (157), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 20/122 (16%), Positives = 37/122 (30%), Gaps = 4/122 (3%)

Query: 194 AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVE 253
                  +GTH + ++  G  +     + S      +     V       +   V+  VE
Sbjct: 7   WNNFFTEFGTHFVNTLTLGGRMSTTVTMDSKATRKLEEKNVDVAMMVKGEY-GPVSASVE 65

Query: 254 TDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGIT---LETWQKGITNHLVAIDRAGLPL 310
               S  S   ++   + +S+    GG P            W   + +H V +     PL
Sbjct: 66  ASASSDKSSKNEFNDAKKDSKTIISGGTPPKSRADPERFREWAVSVPDHPVPVKYTLKPL 125

Query: 311 HF 312
             
Sbjct: 126 TE 127


>UniRef50_B8A565 Complement component 9 n=5 Tax=Cyprinidae RepID=B8A565_DANRE
          Length = 673

 Score = 64.5 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 43/298 (14%), Positives = 78/298 (26%), Gaps = 54/298 (18%)

Query: 123 SRVNGKFSTEFQR--------MKTLQVKDQAVTTRVQVRNRIYTVKTTPT-SELSLGFTK 173
             ++G     +++        +  L    +    RV+ R  + T +      E+S  F  
Sbjct: 335 FGISGSAGANYKQTTTNIIKQLSELTTTKRKTFMRVKGRVELATYRMRQRGLEVSSTFLD 394

Query: 174 ALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDH----VRSSFLLDN 229
            +  +  Q EK       Y +   +  YGTH   +  +G            +R    +  
Sbjct: 395 DVDALPLQYEK-----GQYFS--FLEEYGTHFTKNGKSGGEYQLVYVMNEDIRKQKHVTE 447

Query: 230 QNSQNTVTASAGIAFLNIVNFKVET---------DYISQTSLTKDYLSNRTNSRVQSFGG 280
              +          F      +               +  +  K+         ++  GG
Sbjct: 448 ATVKKCFELGLKADFQLTPAAEGGGEVKPLNDCNSLTNTDTDEKNNKGVIDKVLIEVKGG 507

Query: 281 VP----------FYPGI----TLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPL 326
                          GI        W K IT     I     P++  I P   P      
Sbjct: 508 SAASAVAMKSQLTKDGILDYNQYVEWAKTITILPALIQSEPEPIYNAI-PLSFPD----- 561

Query: 327 VKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMD-DDSCDAKVTNFTFGGVYQ 383
            +     ++ A+  Y    +   C     P  N    +  D  C       + G   Q
Sbjct: 562 AQPRRDNLKRALDEYVAEYSVCKCQ----PCQNGGTVIQIDGQCKCMCLPGSEGVACQ 615


>UniRef50_C6IIH6 Putative uncharacterized protein n=1 Tax=Bacteroides sp. 1_1_6
           RepID=C6IIH6_9BACE
          Length = 493

 Score = 64.5 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 42/236 (17%), Positives = 79/236 (33%), Gaps = 37/236 (15%)

Query: 124 RVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLE 183
              G FS   +     ++  +       +   +  ++   + ++   F      + D+ +
Sbjct: 132 SFTGSFSK--ENFTRHELSTKYSYASADICKDVRWLRLAESVDVLSNF------LTDKFK 183

Query: 184 KNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIA 243
           ++ + M     E  + +YGTHV+  +  G  L       SS + ++   + T    AG+ 
Sbjct: 184 RDISNM--TSPEQFVKDYGTHVLADITIGGVLRVMY--SSSIIKEDDQEKKTKVIKAGLK 239

Query: 244 -FLNIVNFKVETDYIS-QTSLTKDYLSNRTNSRVQ----SFGGV----PFYPGITLETWQ 293
             L  +    + D    +   T     NRT           GG       YP I   +W+
Sbjct: 240 GVLAKIGLSADVDKTVIENVSTSAENINRTLHLEYKGGDGVGGTYNLETGYPTIDKYSWE 299

Query: 294 KGITNH---LVAIDRAG-LPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFN 345
           K +T     L  I+     P++ FI                   V+ AV  Y   +
Sbjct: 300 KSVTAANAGLTKINWDKAYPIYEFISDPVKREQ-----------VKKAVIKYINDS 344


>UniRef50_A7AM15 Putative uncharacterized protein n=1 Tax=Babesia bovis
           RepID=A7AM15_BABBO
          Length = 512

 Score = 64.5 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 44/337 (13%), Positives = 91/337 (27%), Gaps = 66/337 (19%)

Query: 20  DKP---LGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDG 76
             P   LG+   +G++        P+LE       D  ++ +   +     + C      
Sbjct: 8   GNPFGSLGQDKDSGYRN-------PILETHVTISGDKTKSSEQNGLWVRELSTC------ 54

Query: 77  QYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRM 136
              I D    +   E   E+ +E            S SIN+              + +  
Sbjct: 55  --WISDTHDDVGDDELVRELQNEFTVEGSENSELLSASINSMA------------DDKPT 100

Query: 137 KTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMAT----- 191
               V  +   +   +R     +    T ++S  F K +  +    E             
Sbjct: 101 SKHTVNYRIAKSFCAIRES--GIMVPFTGKISSVFIKEVEALPSINEDYGPCTPDVFIVD 158

Query: 192 ---------YLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGI 242
                    +        YGTH+ + +  G  ++  D +    +   + ++   T   G 
Sbjct: 159 PLKSDCSSMHQWVKFFKRYGTHMTSHITIGGQIISIDRM----VEGEKITKMVKTLGGGE 214

Query: 243 AFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPF-----YPGITLETWQKGIT 297
           +   +            +S+       R + ++   GG  F             W K + 
Sbjct: 215 SIYKV--------TDKFSSVMT---GKRESHQMLILGGYYFSGLESNDSKAFNRWSKSVW 263

Query: 298 NHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTV 334
              + I      L  F+              +  + V
Sbjct: 264 ERPMPIRANFTSLEHFMGDKSKSYQHAVRFYRGVQNV 300


>UniRef50_C3ZKZ8 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
           RepID=C3ZKZ8_BRAFL
          Length = 1238

 Score = 63.7 bits (153), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 42/296 (14%), Positives = 78/296 (26%), Gaps = 55/296 (18%)

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA 120
            VM L Y   +T     Y +PD +      ++++E N+    S   Y+            
Sbjct: 188 LVMHLRYHR-RTARYEDYEVPDSMTVQGVYDTDVESNT--FSSMEGYRQYLEQK------ 238

Query: 121 LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICD 180
                    +  FQ          A      +      +     ++L+L F    + +  
Sbjct: 239 ---SAVTSATAMFQEELNKASGYGAGGGAFGLGWYEIFMDDVKPADLNLAFLWDFLRLPV 295

Query: 181 QLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSF---------LLDNQN 231
                         +  IL YGTH I S   G  L       +S                
Sbjct: 296 SYFSIGADTKF---QNFILRYGTHYIQSAKFGGQLKIIKTKEASSDLSVQAFSERAQTDW 352

Query: 232 SQNTVTASAGIAF-------------LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSF 278
            +   T SA  +                  N + E    ++ + + ++ +          
Sbjct: 353 KKTFSTFSAEASMTKSSSWFHKHETKEESENSEGEASQDTEKTSSFEFSNELM----VVQ 408

Query: 279 GG---------VPFYPGIT--LETWQKGITNHLVAIDRAGLPLHFFIK---PDKLP 320
           GG           +   +   L+ W   I ++  A      P+   +        P
Sbjct: 409 GGDQQIAAAITEMYTSSLNTELKAWLDSIKDYPKAFSFVMKPITAALDINFDSLFP 464


>UniRef50_D1K377 Putative uncharacterized protein n=1 Tax=Bacteroides sp. 3_1_33FAA
           RepID=D1K377_9BACE
          Length = 453

 Score = 63.0 bits (151), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 35/265 (13%), Positives = 71/265 (26%), Gaps = 52/265 (19%)

Query: 97  NSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRI 156
            +        Y      +         ++ G  +  F ++       Q     ++  N +
Sbjct: 84  RAYYASDSEEYIKKIGANATLGYNDTLKLTGTITNNFDKISYS---KQYSWASLEKLNTL 140

Query: 157 YTVKTTPTSE-----LSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDA 211
             V    +       L+  F K L                Y    LI  YGTH++T +  
Sbjct: 141 RHVHLDQSVSVLRGYLTSEFVKDLD--------------MYSDIELIQKYGTHILTDISI 186

Query: 212 GAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDY-LSNR 270
           G  L      R+  +  ++           +   ++       +Y   T+L         
Sbjct: 187 GGKLSLLY--RTYAMDTHKEQTVKAGFETALRHYSLT-----ANYDINTTLINKNREQLL 239

Query: 271 TNSRVQSFGGVPFY-------PGITLETWQKGIT-NHLVAIDR---AGLPLHFFIKPDKL 319
               +   GG+          P + +  W K +  +    ID      +P++  +     
Sbjct: 240 VCETIGGTGGIISKINLETGMPDLDINNWDKTVDISTSGVIDVNWKKLIPIYELVSNTS- 298

Query: 320 PGLPGPLVKKLSKTVETAVRHYYTF 344
                         ++ AV  Y   
Sbjct: 299 ----------KRAKLKKAVERYIED 313


>UniRef50_D2E8B6 ORF65 n=1 Tax=Anguillid herpesvirus 1 RepID=D2E8B6_9VIRU
          Length = 750

 Score = 63.0 bits (151), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 45/320 (14%), Positives = 81/320 (25%), Gaps = 27/320 (8%)

Query: 43  LEVLPGGGWDNLRNVDMGRVMDLT--YTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSE- 99
           +E+ P G    L  +    V  L   +  CK ++ G+Y IP             E +   
Sbjct: 428 MEMYPMGMAVGLNGIMASHVAALNGPFHRCK-SQRGRY-IPGNTDLSTALSCTQEYHETK 485

Query: 100 ----VLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNR 155
                  S      T   S       F+      S   +   T +VK        Q  + 
Sbjct: 486 RSAAATHSENKETETRDNSGGGGSVGFAVAAFSGSASAEVDVTKEVKHAISAQVSQSTST 545

Query: 156 IYTVKTTPTSELSLGFT--KALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGA 213
              +     +   LGF+  K +         N         +     +G   +  V+ G 
Sbjct: 546 TAIIAEYKCTVGRLGFSGGKTVYTHAFLSAANALNAKEITLDEFTDLWGVGFVAHVEMGG 605

Query: 214 ALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNI-----VNFKVETDYISQTSLTKDYLS 268
              +   V +           T+       F        V  +        +  +     
Sbjct: 606 MFYRIMTVGTCDAESASRLDETMQDCFKSEFAASGGGWGVTAEAHGHVDKCSGKSSATEK 665

Query: 269 NRTNS-------RVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPG 321
               S        +Q  GG        +  WQ  + +   A+    +P            
Sbjct: 666 GIKLSKFTKNMFTLQIGGGTVST---DMSDWQHSLKDDPKALQYKLVPYTMLKDVFSAKV 722

Query: 322 LPG-PLVKKLSKTVETAVRH 340
           +     V +  + V  A+  
Sbjct: 723 IDQMKKVPRKIEGVLEAIST 742


>UniRef50_C3ZSC8 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
           RepID=C3ZSC8_BRAFL
          Length = 1707

 Score = 62.2 bits (149), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 31/216 (14%), Positives = 59/216 (27%), Gaps = 44/216 (20%)

Query: 153 RNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAG 212
           R  I+    TP  +L++GF +  + + +         A  + +   L +GTH I S   G
Sbjct: 623 RYAIFMDDVTPD-QLNVGFLRDFISLPESYFSPG---AELIFQNFYLRWGTHYIKSAKFG 678

Query: 213 AALVQEDH------VRSSFLLDNQNSQNTVTAS----------------------AGIAF 244
             L           +  S           +T S                           
Sbjct: 679 GQLKIIKTKQATKDLSMSEFATKAERDWKMTMSTFSALATQTKSSSWWHEHETKTESKQA 738

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG---------VPFYPGIT--LETWQ 293
              V+   E+         ++     +N  ++  GG           +   +T  L+ W 
Sbjct: 739 TGQVDAGSESQANRG-QQKQESAQEYSNEMLEVQGGDQKIAAAITEMYTTALTTELKDWL 797

Query: 294 KGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKK 329
           + I ++         P+   +        P   V  
Sbjct: 798 ESINDYPKPFSFVLRPVPDLLDIPFATLFPAGEVDY 833


>UniRef50_A7RGY2 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RGY2_NEMVE
          Length = 485

 Score = 61.0 bits (146), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 44/345 (12%), Positives = 94/345 (27%), Gaps = 39/345 (11%)

Query: 52  DNLRNVDMGRVMDLTYT--NCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQS 109
           D +  + +  + +  Y   +C    +      + +Y    KE         + + +   +
Sbjct: 82  DMMTEIPLEGLYNSDYIAESCIRESNRDTSTKETIYFRSTKE---------VYTTLARTT 132

Query: 110 TTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSL 169
                +  +  L + ++        +            T  ++   I +         S 
Sbjct: 133 AVDEELAADQVLKASLDAVAGDISAKTTESLTGYSIEMTAERLSRGI-SADCLSDFSFSS 191

Query: 170 GFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQED--HVRSSFLL 227
           GF      +      N   +        +   GTH I SV  GA++          SF  
Sbjct: 192 GFMNDFQSLPRVYSNNNRYVFFEKYLRFLKTRGTHFIKSVTFGASVRHYSFGKASQSFSQ 251

Query: 228 DNQNSQNTVTASAGIAFL-NIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGV----- 281
           ++   ++ +  +       + ++ K      ++ +   +      +SRV   GG      
Sbjct: 252 NDFRIKSCIKLAELAKTTVDELDIKDCRGVTAEDTARVN--KMAISSRVVIRGGTLDSRI 309

Query: 282 --PFYPGIT-LETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVE--- 335
              F P    + T+       +V I    + +   +K            K L    +   
Sbjct: 310 NLLFTPTDDKIRTFLDAGYWEVVPISYTMVEIWELLKIKFFGTPNYARAKNLEDYFKGVL 369

Query: 336 ----------TAVRHYYTFNTHPGCTNVDSPN-FNFQANMDDDSC 369
                       +   Y  +T               Q  MDD  C
Sbjct: 370 MFECSQIVINGYIMQRYVRSTWSSDDRPSYECQLRSQGCMDDGDC 414


>UniRef50_B6H8Y2 Pc16g03220 protein n=1 Tax=Penicillium chrysogenum Wisconsin
           54-1255 RepID=B6H8Y2_PENCW
          Length = 760

 Score = 60.3 bits (144), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 35/231 (15%), Positives = 69/231 (29%), Gaps = 18/231 (7%)

Query: 84  VYTIPQKESNLEMNSEVLESWMNYQSTTSLS--------INTELALFS---RVNGKFSTE 132
           +Y  P      +    V E+     ++ + S         +    LF       G FS  
Sbjct: 255 LYKYPLYTVTDDSYVNVFETANALSNSLASSNFSSMDVEASIGGGLFGYSAAAKGGFSKS 314

Query: 133 FQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT-SELSLGFTKALMDICDQLEKNQTK--M 189
                    + +  T  +        +       EL+ G  +AL  I    E  +     
Sbjct: 315 DSDALATSEQSKQRTMNITYNFPRVVLHLDNDTLELTKGCKEALDHIIKLREDPKVASWQ 374

Query: 190 ATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLN-IV 248
                      +G    T+V+ G  L  ++   SS +       N +  SA ++F + +V
Sbjct: 375 ERRAIIKFYQKFGHFFATNVELGGKLFSKEEFSSSDVGKTAEKSNAMKISAALSFSSPVV 434

Query: 249 NFKVETDYISQTSLTKDYLSNRTNSRV--QSFGGVPFYPGITLETWQKGIT 297
                    SQ++      ++  +  +  ++ GG           W   + 
Sbjct: 435 QASASYSQESQSASGSASQTSNMSKALSWEAVGGDTTLCN-NPPEWSSTVK 484


>UniRef50_Q54I05 Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum
           RepID=Q54I05_DICDI
          Length = 340

 Score = 60.3 bits (144), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 37/219 (16%), Positives = 73/219 (33%), Gaps = 20/219 (9%)

Query: 99  EVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYT 158
           E ++   N     S  ++  L++ + V  KFS   + +     K+  +T+ V V    + 
Sbjct: 9   ESIDQKSNQTDIGSFKLD-SLSISAEVKSKFSK--ESLDVKVGKEVYLTSSVSVPRLEFC 65

Query: 159 VKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQE 218
           +      +LS  F   L ++    E             +   YG         G  +   
Sbjct: 66  I-NPLKVKLSDEFYSKLNNVETHGE----------LIKVFKEYGEFYPKRYILGGMITNH 114

Query: 219 DHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSF 278
           +  + + + + ++   +++A    A    V         S T   K   +   +S+    
Sbjct: 115 ETQKFTTIENLESKLLSLSAGVNAAI-GPVKVGGSVGGESATDEKKSKQNEENSSKKDVI 173

Query: 279 GGVPFYPGITLETWQKGIT--NHLVAIDRAGLPLHFFIK 315
           GG P   G     W   ++  N+   I     P+   IK
Sbjct: 174 GGDPSKTG---SEWVSSLSDINNWGIIGIDVYPIMDLIK 209


>UniRef50_Q2GRU1 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
           RepID=Q2GRU1_CHAGB
          Length = 924

 Score = 60.3 bits (144), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 38/260 (14%), Positives = 73/260 (28%), Gaps = 19/260 (7%)

Query: 71  KTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTS----LSINTELALFSRVN 126
            T ED    IP ++  +P    N     EV      +Q + +     S + E ++     
Sbjct: 301 LTAEDVNAPIPAKLGAVPSYVVNDRSRIEVTTVMSEFQESMAKNHFSSTSVEASVSGGYA 360

Query: 127 GKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKAL----MDICDQL 182
           G FS        +  +  +  +          + +     +S+           ++ D L
Sbjct: 361 G-FSVGVT--GGVASESSSGQSSSNKTYSKRMIASYMFPRVSVFLRPEDLEPTQELRDAL 417

Query: 183 EKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGI 242
           E  +      +   L   +G     +   G  L     V  +        + +  AS G+
Sbjct: 418 EAVRKTKNINMLRNLYQTFGHLFCYTATLGGCLQTTKIVTGNEQTQQSKEKESFKASVGV 477

Query: 243 AFLNIVNFKVETDYISQTSLTKDYLSNRTNS----RVQSFGGVPFYPGITLETWQKGI-- 296
           A               +T  + D     +N+      ++ GG           W   +  
Sbjct: 478 AVSTPFGVGGSVKASHETQDSSDSFQRTSNTSEAMTFEATGGNSILAA-NPPAWSSSVAD 536

Query: 297 -TNHLVAIDRAGLPLHFFIK 315
             N  V       P+   I 
Sbjct: 537 FNNWRVIEQSDLHPISETIS 556


>UniRef50_UPI0000E45FB2 PREDICTED: similar to apextrin n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E45FB2
          Length = 151

 Score = 60.3 bits (144), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%)

Query: 40  LPVLEVLPGGGWDNLRNVDMG-----RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNL 94
             +L   P GG      VD G     R++DLTY N + + DGQY +PD+V  +P+     
Sbjct: 44  YNILTGDPDGGDVTNGGVDPGLMVTRRILDLTYHNGELSLDGQYQVPDQVTFVPRDSC-- 101

Query: 95  EMNSEVLESWMNYQSTTSLSINTE---LALFSRVNGKFS 130
             +S++  +   YQ   +  +  +     LF+      S
Sbjct: 102 NHDSQLFHNARTYQEKLARDVELDDDLRKLFAGFEFSKS 140


>UniRef50_Q23JJ5 MAC/Perforin domain containing protein n=12 Tax=Tetrahymena
           thermophila SB210 RepID=Q23JJ5_TETTH
          Length = 744

 Score = 60.3 bits (144), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 29/270 (10%), Positives = 83/270 (30%), Gaps = 44/270 (16%)

Query: 74  EDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEF 133
            D Q+I+ DE   I  ++  L+ + ++ ++     +    +       +       S + 
Sbjct: 160 SDNQFIVADE---IQIEQIELQPDIKIFQNEQELSNVWIQAAQN--GYWLGGQYSHSQDL 214

Query: 134 QRMKTLQVKDQAVTTRVQVRNRIYTVKTTPT-SELSLGFTKALMDICDQLEKNQTKMATY 192
            ++     +     +  Q+   +  +        L+    +A+  +         + +  
Sbjct: 215 NQIFEKFFQGDQEMSVSQMAKNVLRLTFKSDNLSLNKYAQRAVNALPQ-------EYSPE 267

Query: 193 LAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVN--- 249
           +    + ++GTH+      G  + +    +S               +A  +F   ++   
Sbjct: 268 VYNDFLESWGTHISVDTYIGGMIEKVSAFKSC-------------VNASPSFNGGLSPQQ 314

Query: 250 FKVETDYISQTSLTKDYLSNRTNSRV-QSFGGVPFYPGITLETWQKGITNHLVAIDRAGL 308
            +   +     +    Y + R    V   FGG P         W+  I+ +   +     
Sbjct: 315 VEQALNNELNGNPADGYFAARRKIAVDHRFGGNP----ENQSNWENTISQNPALLKINKF 370

Query: 309 PLHFFIKPDKLPGLPGPLVKKLSKTVETAV 338
                +  D           ++ + ++ A+
Sbjct: 371 VSWDSLVAD----------VQVKQNLQQAI 390


>UniRef50_UPI000180CCD0 PREDICTED: similar to complement component C6 n=1 Tax=Ciona
           intestinalis RepID=UPI000180CCD0
          Length = 592

 Score = 59.9 bits (143), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 50/316 (15%), Positives = 94/316 (29%), Gaps = 42/316 (13%)

Query: 75  DGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFST--- 131
           D  Y IP  V +  Q    +    ++ ES  N  +TT  S+N  L    +V G       
Sbjct: 223 DAYYRIPANVASFRQLYEIILSTPKIYESGANLLNTTKDSLNYNLNFGGQVLGVAGNAGL 282

Query: 132 ------EFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSL--GFTKALMDICDQLE 183
                 E   + ++Q +       ++       V      +L     F   +M++ D   
Sbjct: 283 TQNSLIENVVIDSVQNEQMNTYVSMKAAVNTAQVTLQDPEDLEPTTSFMSRVMELPD--- 339

Query: 184 KNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT-------V 236
              +  +       + +YGTH + S   G    +       +L     S  T       +
Sbjct: 340 ---SGFSYDKYMSFVADYGTHYVASGKLGGMYEETQVYSRCWLDSKSFSVYTPKEWSEVL 396

Query: 237 TASAGIAFL-----NIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPG----- 286
              A  +F          F     +I  T          +   V   GG           
Sbjct: 397 QDCATQSFYYNLDPTTTTFTDTCKHIDSTGQANFLTDEISRKLVYVTGGSIATSSDLKLS 456

Query: 287 ---ITLETWQKGITNHLVAID--RAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
               T + W + ++             P+   I    +P +     + L+  ++ A+  +
Sbjct: 457 FVKETWDAWIQSVSTGPTLNTDLFHLRPISDLIYSTHIP-IDRKRREILAGFIDQAIELH 515

Query: 342 YT-FNTHPGCTNVDSP 356
            T ++ +  C     P
Sbjct: 516 LTPYDGYTQC-EPCRP 530


>UniRef50_A7BVI9 Membrane attack complex component/perforin/complement C9 n=1
           Tax=Beggiatoa sp. PS RepID=A7BVI9_9GAMM
          Length = 526

 Score = 59.9 bits (143), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 35/271 (12%), Positives = 85/271 (31%), Gaps = 41/271 (15%)

Query: 64  DLTYTNCKTTEDGQYIIPDEVYT-----IPQKESNLEMNSEVLESWMNYQSTTSLSINTE 118
           +  + + +T     Y++PD         IP  +S  ++  E  +SW  ++   ++     
Sbjct: 55  NRVFDSVETA--KTYLVPDGYEVNESPPIPADKSQCQLIVE--DSWEEFEKHLNIDAQVA 110

Query: 119 LALFSRVNGKFSTEFQRMKTLQV--KDQAVTTRVQVRNRIYTVKTTPTSELSL--GFTKA 174
            +        FS + +  +T  +  ++ +           +T+     ++      F + 
Sbjct: 111 ASHNV-----FSVDVKTGQTKPLRPEEDSYYALRTFFIPFWTLYLPDVTDFEDKKAFKQ- 164

Query: 175 LMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQN 234
             +I    +    K      E     YGTH I     G   +    +  S  +  Q+ + 
Sbjct: 165 --NIPTPFQHRHRKE----YEKFFDRYGTHYIKRAWIGGKAMLIFSIAKSTGMTKQDIRK 218

Query: 235 TVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFY-------PGI 287
            + A   +    ++          + SL+K  L   +   V + GG              
Sbjct: 219 GLNACYALTNEQML-------ADIKESLSK--LHKHSECLVLAQGGEATKLGALSLLDEA 269

Query: 288 TLETWQKGITNHLVAIDRAGLPLHFFIKPDK 318
               W   +  +   ++     +   ++ + 
Sbjct: 270 RYSEWLATVKENPKVVEFEAAGIWTLLRDEN 300


>UniRef50_A2TUN8 Guanosine polyphosphate pyrophosphohydrolase/synthetase-like
           protein n=1 Tax=Dokdonia donghaensis MED134
           RepID=A2TUN8_9FLAO
          Length = 1102

 Score = 59.1 bits (141), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 29/240 (12%), Positives = 68/240 (28%), Gaps = 24/240 (10%)

Query: 84  VYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKD 143
           ++      S +  +  V   ++         +    +L S      S  +         D
Sbjct: 36  LFKGGSSTSKITSSPAVSYHFVTTPYEYEKELLRTDSLDSPFQAINSHAYYEAFEADGSD 95

Query: 144 QAVTTRVQVRN--RIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNY 201
           + +    Q R      +++T+ T  L          +   +            E  I  Y
Sbjct: 96  KLLFVYTQKRKPIERKSLRTSSTKTLDSAMVADFSRLGRDIT----------PEGFIHRY 145

Query: 202 GTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTS 261
           GTH    V  G   ++ + ++++  + +   ++                K      +  S
Sbjct: 146 GTHYADQVVYGGIFLKRNLIKNTDYIYSPYEKDEFQQQV---------VKDIIATHTGAS 196

Query: 262 LTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPG 321
               Y++    S   + GG       T   W+  ++ +   I+          +   +P 
Sbjct: 197 DPDPYINAGQ-SNTYTIGGNKDAQWFT--DWEGTVSQNSKPIEVTLQTFSELFRTVSMPE 253


>UniRef50_C3ZP97 Putative uncharacterized protein n=2 Tax=Branchiostoma floridae
           RepID=C3ZP97_BRAFL
          Length = 631

 Score = 58.7 bits (140), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 27/163 (16%), Positives = 58/163 (35%), Gaps = 11/163 (6%)

Query: 131 TEFQRMKTLQVKDQAVTTRVQVRNRIYT--VKTTPTSELSLGFTKALMDICDQLEKNQTK 188
             +  ++       AVT         Y   +      +L+L F +  + + +        
Sbjct: 420 YRYVFLRLQVSLTPAVTGESFTCGHRYEIFLDFVNPEDLNLAFMRDFLSLPNSYFSVG-- 477

Query: 189 MATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIV 248
            A    +  I  +GTH ITS   G  L     +++  + +   S+ + + +A   F  ++
Sbjct: 478 -ADREYQWFIQRWGTHYITSAKFGGQLKI---IKTKEITEE-VSEESFSQAAQSDFKKLL 532

Query: 249 NFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLET 291
           +        +QT  +  + S+ T +  QS  G       +  +
Sbjct: 533 STYSAQ--QTQTKSSSWFHSHETKNERQSASGEQSQDTTSETS 573


>UniRef50_Q94J22 Os01g0748900 protein n=2 Tax=Magnoliophyta RepID=Q94J22_ORYSJ
          Length = 553

 Score = 58.7 bits (140), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 28/150 (18%), Positives = 43/150 (28%), Gaps = 21/150 (14%)

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
            I NYGTH+ITSV  G      D V       +Q S+               +       
Sbjct: 173 FIENYGTHIITSVTVGGK----DEVYIKQHSSSQLSELEFRNYVKEIGSERFSDGDS--- 225

Query: 257 ISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKP 316
               +   +Y         +  GG           W K + +    I    LP+   +  
Sbjct: 226 -KLNATPINYSEKDMTVIFRRRGGCDLVQNFN--DWIKTVQSAPDVIGMTFLPIVSLVGD 282

Query: 317 DKLPGLPGPLVKKLSKTVETAVRHYYTFNT 346
             +PG          K +  A+  Y  +  
Sbjct: 283 --MPG---------KKHLARAIELYLKYKP 301


>UniRef50_D2VPS9 Predicted protein n=2 Tax=Naegleria gruberi RepID=D2VPS9_NAEGR
          Length = 519

 Score = 58.3 bits (139), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 51/359 (14%), Positives = 101/359 (28%), Gaps = 51/359 (14%)

Query: 1   MNSFMALVLIWMII-------ACAEADKPLGET-GTTGFQICKNAL-KLPVLE----VLP 47
           MN+    VLI+ +I       A + + K           Q   N +  + VL       P
Sbjct: 1   MNTLNLFVLIFALILGMLINKANSSSLKLRALPNVKLQIQEQINKMGNICVLSMSGLDCP 60

Query: 48  GGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNY 107
           G   D   N     +   + +  + T D   II    Y+      NL +      + ++ 
Sbjct: 61  GKAQD--MNFKTSII--RSASGERLTVDNLPIIAGVGYSRADNSINLPILKSTQATTVSG 116

Query: 108 QSTTSLSINTELALFSRVN------------GKFSTEFQRMKTLQVKDQAVTTRVQVRNR 155
             T + SIN+    F+ ++              +      M   +     +      +  
Sbjct: 117 SQTLTRSINSATDYFNLLHPGDGAEITNTGLYSYGQTATDMIFKKFFQGNLKGYNIQKQF 176

Query: 156 IYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAAL 215
                     E +  F + +  +          M   L  ++I ++G  + T +  G  +
Sbjct: 177 YTHRVEISNIEPTDDFKRIIDLLP-------ENMDQDLYMMVINSFGDSIATKITYGGIV 229

Query: 216 VQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLT-KDYLSNRTNSR 274
                VRS +   +      +     I            +  + T      YL  +    
Sbjct: 230 DMTTTVRSCYNDPSMEQYLDIQLQMSI------------NGDTDTKKLPNGYLRYQRVGS 277

Query: 275 VQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKT 333
           +   GG P    I   T  +    + V +    +P+               +    +  
Sbjct: 278 LDIIGGNPQLSNINQRT--QTFAKNPVPVKMEIIPIWRAFPAGIKQENMKKVYTDYAAA 334


>UniRef50_A5B4D4 Putative uncharacterized protein n=1 Tax=Vitis vinifera
           RepID=A5B4D4_VITVI
          Length = 301

 Score = 58.0 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 20/133 (15%), Positives = 35/133 (26%), Gaps = 13/133 (9%)

Query: 196 LLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETD 255
           + I  +GTHVI  V  G           S  L     Q  +   A   F +      +  
Sbjct: 26  MFIEKFGTHVIVGVKMGGKDTVYVKQLYSSTLQPTEVQKQLKDIADKRFSDAPGSYGKVS 85

Query: 256 YIS-----------QTSLTKDYLSNRTNSRVQS--FGGVPFYPGITLETWQKGITNHLVA 302
                          TS +  Y +  +          G      +    W   ++     
Sbjct: 86  REKFEIKEHGMPFMDTSTSSAYSNKESQDITFISKRRGGSSKTNLPHSAWIPTVSFEPDV 145

Query: 303 IDRAGLPLHFFIK 315
           I  + +P+   + 
Sbjct: 146 ISMSLVPITSLLS 158


>UniRef50_D2VJY2 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VJY2_NAEGR
          Length = 495

 Score = 57.2 bits (136), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 35/216 (16%), Positives = 73/216 (33%), Gaps = 32/216 (14%)

Query: 128 KFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQT 187
             ++  + +     K   V    Q +   + V+ T T +++  F + +  + +       
Sbjct: 141 SHNSGAENIYQNYFKGDMVVMDAQQQYITHQVE-TNTIQVTEDFQRIIDILPN------- 192

Query: 188 KMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNI 247
            M   L  L+I ++G  ++TSV+ G  +     VRS F   N  S   +     +     
Sbjct: 193 AMDRDLYNLVITSFGDSILTSVNYGGVVDMVVSVRSCFSDANMKSYLDIQLQLSVD---- 248

Query: 248 VNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAG 307
                  +    +SL   Y+     +++   GG P      ++   K    + V +    
Sbjct: 249 -------NNTDTSSLPTGYIRYNKVAQLDIVGGNPQI--FNVKERVKTFEQNPVPVKFLS 299

Query: 308 LPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYT 343
           +P+         P  P        + ++T    Y  
Sbjct: 300 IPIW-----RAFPAGP------KQENMKTVYNEYVN 324


>UniRef50_B9IGR8 Predicted protein n=10 Tax=Embryophyta RepID=B9IGR8_POPTR
          Length = 560

 Score = 57.2 bits (136), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 42/273 (15%), Positives = 72/273 (26%), Gaps = 54/273 (19%)

Query: 87  IPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL-FSRVNGKFSTEFQRMKTLQVKDQA 145
           I ++ S +    E++E +           N    L     N  FS               
Sbjct: 67  IGRQSSGVCTFHEMVEYFNQ-------KANLSGGLPLGSFNSAFS--------------- 104

Query: 146 VTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAE-----LLILN 200
             T  +  +   T   +            L      L +N  +      +       I N
Sbjct: 105 -FTGSKHIDAAATKTLSMDGYYIPLAKVQLKRSPLVLHENVIRAVPTFWDPPSLASFIEN 163

Query: 201 YGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQT 260
           +GTHVITSV  G   V       S  L     ++ V       F +      E    S  
Sbjct: 164 FGTHVITSVTIGGKDVIYVKQHQSSPLSTMEIKHYVQDIGNQRFSDT-----EGHMSSGP 218

Query: 261 SLTKDYLSNRTNS-------RVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFF 313
              KD  S   +          +  GG           W + + +    I+   +P+   
Sbjct: 219 MKLKDKASPMISPYFFDVTVIFRRRGG--DDLEQNHIRWARTVESSPDVIEMTFVPIADL 276

Query: 314 IKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNT 346
           +           +     + +  A+  Y  +  
Sbjct: 277 L-----------VGVPGKEHLSRAIALYLEYKP 298


>UniRef50_C3ZA36 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZA36_BRAFL
          Length = 390

 Score = 56.4 bits (134), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 40/282 (14%), Positives = 83/282 (29%), Gaps = 51/282 (18%)

Query: 55  RNVDMGRVMDLTYTNCKTT-EDGQYI---IPDEVYTIPQKESNLEMNS----EVLESWMN 106
           R  + G          + T E  +Y    +PD++      +++LE+ +    E    ++ 
Sbjct: 116 RGSNTGDTFSPPSQEVRMTFEHREYKDFHVPDQMTVQGVYDTDLELYTFSGVEEYRHYLE 175

Query: 107 YQSTTSL-----------------------SINTELALFSRVNGKFSTEFQRMKTLQVKD 143
            +S  +                         + +     S+  G  S             
Sbjct: 176 DKSAVTSAKGMFQQEMNKVQGHGGGGGLFGFVASAGGGQSKQTGSDSQTSNTQSNSLAGA 235

Query: 144 QAVTTRVQV----------RNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYL 193
           Q   T  +           R  I+     P  +L LG  +  + +           A   
Sbjct: 236 QLTETSTETYISMLELNVFRYEIFLDSVRPQ-DLELGILRDFLTLPTSYFSIGADRAF-- 292

Query: 194 AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVE 253
            +  IL +GTH ITS   G  L     +  +     + S+ +   +A   F  + +    
Sbjct: 293 -QNFILRHGTHYITSAKLGGQL----KMIKTKTATAEVSKESFAQAAQSDFKKVFST-FS 346

Query: 254 TDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKG 295
               + T  +  +  + T +  Q+  G       +  + +  
Sbjct: 347 AK-QTMTKSSSWFHDHETKNEKQTSSGQETQDTASQSSNENQ 387


>UniRef50_A3YG19 Putative uncharacterized protein n=1 Tax=Marinomonas sp. MED121
           RepID=A3YG19_9GAMM
          Length = 588

 Score = 56.4 bits (134), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 42/297 (14%), Positives = 77/297 (25%), Gaps = 40/297 (13%)

Query: 102 ESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKT 161
            S ++Y  + S   +T+ +      G  S+ F+ +++                 + T+  
Sbjct: 78  SSEVSYLKSISNLFSTQYSG-VIFKGSISSTFKSVESNNN--NNYFITETRNRSLGTLSF 134

Query: 162 TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHV 221
                    F   L                     +   YG + I S + G  L     V
Sbjct: 135 NGD------FKDYLSAKARDF----INDNDISPVDVFAKYGIYFIKSFEVGGRL----SV 180

Query: 222 RSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGV 281
            ++        Q         A+  +     ET+  ++   T   L++ ++    + GG 
Sbjct: 181 DAASEQSQYTKQTEFNLEVKAAYKAL-----ETENNTEIQKTIKKLASNSSYSFYAEGGD 235

Query: 282 PF------YPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVE 335
                         + W K I +         L     +    +P        K    ++
Sbjct: 236 LDIISSQSPSSDEFQLWLKSIASSP------TLTWFNNLDDALVPIWTLAKNDKRQAQLK 289

Query: 336 TAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDV 392
           +    YY  N   G                D   D   TN     VY  C       
Sbjct: 290 S----YYQ-NKITGGYLRSMYFIAHTRKEGDGYSD-PDTNTPSKNVYITCKNYGQKD 340


>UniRef50_C3ZUI3 Putative uncharacterized protein n=2 Tax=Branchiostoma floridae
           RepID=C3ZUI3_BRAFL
          Length = 783

 Score = 56.0 bits (133), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 32/214 (14%), Positives = 66/214 (30%), Gaps = 42/214 (19%)

Query: 153 RNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAG 212
           R  I+     P ++L+L F +  +++       +        +  I+ YGTH I S   G
Sbjct: 107 RYEIFMDDVKP-ADLNLAFLRDFLNLPVSYFSIRADQ---YFQNFIIRYGTHYIKSAKFG 162

Query: 213 AALVQED------HVRSSFLLDNQNSQNT-----VTASAGIAFLNIVNFKVETDYISQTS 261
             L           +      +   ++        +A A     + +  + ET   SQ +
Sbjct: 163 GQLKIIKTKEASKELSIQSFSEKAQTEWKKAFSTFSAEASQTKSSSLWHEHETKTESQNA 222

Query: 262 LTKDYLSNR----------------TNSRVQSFGG---------VPFYPGIT--LETWQK 294
             +    +                 +N  +   GG           +   ++  L+TW +
Sbjct: 223 EGEASEGSDAAAKQSQTENLHSFEFSNEMIVVQGGDQRIAAAITEMYTTSLSTELKTWLE 282

Query: 295 GITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK 328
            I ++  A      P+   +  +     P   V 
Sbjct: 283 SIKDYPKAFSFIMKPITAVLDINFDSIFPNGAVD 316


>UniRef50_B3L1A1 Putative uncharacterized protein n=1 Tax=Plasmodium knowlesi strain
           H RepID=B3L1A1_PLAKH
          Length = 663

 Score = 56.0 bits (133), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 86/564 (15%), Positives = 145/564 (25%), Gaps = 120/564 (21%)

Query: 20  DKPLGET---GTTGFQICKNALKLPVLEVLP-GGGWDNLRNVDMGRVMDLTYTNCKTTED 75
             PLG+       G++      KL              L     G    L+YT C  T  
Sbjct: 59  GNPLGDPLYAVDMGYRRYVLRNKLNTRSDQECEENEHPLSENHGGNQDSLSYTACMRTN- 117

Query: 76  GQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTT-SLSINTELALFSRVNGKFSTEFQ 134
                          + +      ++    +      +    T+  +         + + 
Sbjct: 118 --------------VKCSSGKEMHIINGLDDINKVYKTYKFETQYDIHPFNA----SNYY 159

Query: 135 RMKTLQVKDQAVTTRVQVRNRIYTVKTTP--TSELSLGFTKALMDICDQLEK-------- 184
           RM   ++         +     Y V  +      L   F   L ++ +  +         
Sbjct: 160 RMLVERINKGDSIILRKEICVKYLVSLSEGGDDMLDPFFVNMLSELGNNYQNIGGDKYKC 219

Query: 185 --NQTKMATYLAE---------LLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQ 233
                +   Y  +              YGTH I+ V  G  ++    V + +L  +    
Sbjct: 220 DVQSYRNNKYSQDCLKTVTPWMTFFNLYGTHFISGVYYGGRVINNLFVENDYLPKDGRKI 279

Query: 234 NTVTASA-------------GIAFLNIVNFKVETDYISQTSLTKD--YLSNRTNSRVQS- 277
              T                GI F   V    +  +I+Q  +  +     +     +Q+ 
Sbjct: 280 RLYTKRLNPFGGVSKRGHHRGILFFGSVISSEKVRHIAQRVVMVEGGGEGDVEIPSMQTG 339

Query: 278 ----FGGVPFYPGITLETWQKGITNHLV-AIDRAGLPLHFFIKPDKLPGLPGPLVKKLSK 332
                 G       + + W+  I    V  +     P   FIK                 
Sbjct: 340 EDNPQAGKNNIRNFSHKKWKNSIKGSSVKPVKLILKPFSDFIKS-----------ADEKN 388

Query: 333 TVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKV---------TNFTFGGVYQ 383
               A+  Y   N      N     + FQ N  +   D             N  F  V  
Sbjct: 389 AYYKALEFY--SNLTYTNYNP----YPFQLNRSEGDLDKMHIKRWHQYIDKNINFN-VMP 441

Query: 384 ECTE----LSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLK 439
           +C +    LSG ++       +       CP        LS+    G +    K      
Sbjct: 442 KCKKGEKILSGFIITNKKRLYDDNNVMHVCP--------LSRECSSGMNIESDKSFEFGW 493

Query: 440 IFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFG-----GVFTDKTINPM-TNAQS 493
           + C           K   +    V         G  F      GV T+  I P  +N  S
Sbjct: 494 VLCSRENPQEIHQMKKLVQGNNTVITCPSNMKIGFGFSLTMQKGVHTNMNIEPCGSNVAS 553

Query: 494 C---------PAGYIPLNLFESLK 508
           C         P G++ +N   S K
Sbjct: 554 CGLSPKVGESPQGFLWVNCLPSNK 577


>UniRef50_C3YBL0 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
           RepID=C3YBL0_BRAFL
          Length = 1491

 Score = 55.6 bits (132), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 46/348 (13%), Positives = 95/348 (27%), Gaps = 93/348 (26%)

Query: 62  VMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTT---SLSINTE 118
           ++  +    +T ED +  +PD +      ++++E N+    S   Y+      S   + +
Sbjct: 325 IVQRSCNGLQTYEDHE--VPDTLTVQGLYDTDVESNT--FASMEGYREYLEQKSAVTSAK 380

Query: 119 LALFSRVNGKF----------------------------STEFQRMKTLQVKDQAVTTRV 150
                 +N                               S+ FQ     + +     T+ 
Sbjct: 381 AMFQQELNKAAGHGAGGGIFGLGYSAGGGGSNQNARSDQSSNFQAGSQAEGRLSDKNTQT 440

Query: 151 QV--------RNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYG 202
            +        R  I+     P  +L+L F +  + +                +  I+ YG
Sbjct: 441 YMALLEMNVFRYEIFMDDVEPD-DLNLSFLRDFLKLPVSYFSIGADQ---DFQNFIIRYG 496

Query: 203 THVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVN-FKVETDYI---- 257
           TH I S   G  L     +  +     + +    +  A   +    + F  E        
Sbjct: 497 THYIKSAKFGGQL----KIIKTKEASKELTIQAFSERAQTEWKKAFSTFSAEASQTKSSS 552

Query: 258 --------------------------SQTSLTKDYLSNRTNSRVQSFGG---------VP 282
                                     +QT     +    +N  +   GG           
Sbjct: 553 WWHEHETRKESQKAEGEASAGSEAAATQTQAENLHSFEFSNEVIVVQGGNQRIAAAITEM 612

Query: 283 FYPGIT--LETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVK 328
           +   ++  L+TW   I ++  A      P+   +  +     P   V 
Sbjct: 613 YTTSLSTELKTWLDSIKDYPKAFSFIMKPITAVLDINFDSIFPNGAVD 660


>UniRef50_C6I3S0 Putative uncharacterized protein n=3 Tax=Bacteroides
           RepID=C6I3S0_9BACE
          Length = 486

 Score = 55.3 bits (131), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 34/240 (14%), Positives = 65/240 (27%), Gaps = 29/240 (12%)

Query: 76  GQYIIPDEVYTIPQKESNL------EMNSEVLESWMNYQSTTSLSINTELALFSRVNGKF 129
              I  DE+   P K +        +       S          ++N +  + +++   F
Sbjct: 78  RDQITKDELSFTPAKINEAILHGRAQSRIAYGTSIDKLTKKL--NVNVKTKIGTKILKVF 135

Query: 130 STEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKM 189
           S + +           + +  +V     T + T            L D      +    +
Sbjct: 136 SLDLEATINQNSTSNNLNSFYKVDALKTTRRLTLPYTSPSRLKYFLSD------EFLADL 189

Query: 190 ATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVN 249
                + +I  YGTHV+T +  G         +          +    ++       + +
Sbjct: 190 KELSGQEIIQKYGTHVMTDILLGGNFSAFYTGKYESTDQFNEQEFKAKSN-----FLLSS 244

Query: 250 FKVETDYI----SQTSLTKDY---LSNRTNSR---VQSFGGVPFYPGITLETWQKGITNH 299
            K  T Y             Y        NS     QS  GV     I    W   ++ +
Sbjct: 245 VKAGTKYDRTLFKSFKQVNVYIKTQGGTVNSSAIISQSPDGVLDNVSIDYTGWINSVSQN 304


>UniRef50_Q4MYN1 Putative uncharacterized protein n=2 Tax=Theileria
           RepID=Q4MYN1_THEPA
          Length = 348

 Score = 54.9 bits (130), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 31/223 (13%), Positives = 56/223 (25%), Gaps = 43/223 (19%)

Query: 138 TLQVKDQAVTTRVQVRNRIYTVKTTPTS--ELSLGFTKALMDICDQLEKNQ--------- 186
                +++    V+    +Y          EL   F + +  + + +E  +         
Sbjct: 139 NDITFNKSKFKIVKCYCSLYESGLITPFHGELRGEFVEMVGKLPNTVESTECPIDIFITE 198

Query: 187 --TKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAF 244
             +     +   L   YGTH+ T    G   +  + V +  L    +      A      
Sbjct: 199 LESCKNLRIWINLFKTYGTHITTYAMTGGKFINMESVVNINLQARDSDIKNTKAKRT--- 255

Query: 245 LNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGIT------LETWQKGITN 298
                   E          +    N+    +   GG  F   +          W K I  
Sbjct: 256 -------GEASSEFSEIFRRRIKGNKIKKHLWVIGGS-FVNNLEQIDPKMFSKWVKTIDK 307

Query: 299 HLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
             + I      L         P           +T   AV +Y
Sbjct: 308 RPMPIKARFSEL-----SMFFPE--------KHETYMKAVEYY 337


>UniRef50_B6VN53 Putative uncharacterized protein n=2 Tax=Photorhabdus
           RepID=B6VN53_PHOAA
          Length = 513

 Score = 54.9 bits (130), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 26/216 (12%), Positives = 56/216 (25%), Gaps = 37/216 (17%)

Query: 127 GKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQ 186
              S             +   +R+Q    +Y +K++    L     +++    D+ +  +
Sbjct: 131 FSASLRVDFDTDSLTAFENAFSRIQYTYDLYILKSSAE-ALKEFLKESVKTALDKADTEE 189

Query: 187 TKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLN 246
                     L   +G+H ++ V  G                     N+    A  +F  
Sbjct: 190 DM------NDLFNTWGSHFLSGVIMGGCAQYASSTNKYTSNLT----NSFDVVAAASFAG 239

Query: 247 IVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVP--FYP------------------G 286
            +     T    Q  + K    + +N +  + GG    F P                   
Sbjct: 240 FIGLSARTANSFQEDIKK--FRSTSNIKTHAIGGDLSRFDPFGGATSAEQPSAEEIAAAK 297

Query: 287 ITLETWQKGITNHLVAIDRA----GLPLHFFIKPDK 318
              E W+  + N    ++         +        
Sbjct: 298 KAFEDWKASVPNAPELVNFTDSNPLTGIWELCSDRT 333


>UniRef50_D2VN11 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VN11_NAEGR
          Length = 544

 Score = 54.9 bits (130), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 31/218 (14%), Positives = 60/218 (27%), Gaps = 22/218 (10%)

Query: 102 ESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTR-VQVRNRIYTVK 160
             +   +   +   N        V    + E  +     +         V  +   Y+VK
Sbjct: 137 MHFSKVRDFYNHVYNMNSTSHVAVLYSDTLENAKQTFTTLFKSKTDIHAVDTKYAHYSVK 196

Query: 161 TTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDH 220
           TT   + +  F   L  +              + E  I  +G+ V+TSV  G  + Q   
Sbjct: 197 TTKQLQFTTSFQTILQKLPMSYHSK-------IYERFINIFGSQVMTSVLYGGLVGQTSI 249

Query: 221 VRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG 280
           ++S +            +S      +    +      S   +   +L           GG
Sbjct: 250 IKSCY------------SSESAVKYSQARLQKLMTGTSDVDIPNTFLKYSKIISSDIIGG 297

Query: 281 VPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDK 318
            P    I  +        +   I    +P+   I  + 
Sbjct: 298 NPEISSI--KKRVSTFPKNSSPIKFQTVPIWKLIPEEN 333


>UniRef50_UPI00005853E1 PREDICTED: similar to apextrin, partial n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI00005853E1
          Length = 131

 Score = 54.5 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 27/126 (21%), Positives = 46/126 (36%), Gaps = 15/126 (11%)

Query: 7   LVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGR----- 61
           L+L+W   A         +      +         +LE  PGG   N   +D G      
Sbjct: 9   LMLVWRAAA--------AQPKHPNVKFLGIG--YNILEGNPGGKGLNEGGLDPGLKVTKK 58

Query: 62  VMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL 121
           ++ L+Y   K T+D +  +PDEV    +  S+       +    +YQ+     I  E  +
Sbjct: 59  IVSLSYDEEKLTDDNESSVPDEVIYHKRGGSSAGCRVHSVYGAKSYQTELKTQIKFEGGV 118

Query: 122 FSRVNG 127
              + G
Sbjct: 119 AKVLKG 124


>UniRef50_B9HDI2 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HDI2_POPTR
          Length = 597

 Score = 54.5 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 54/381 (14%), Positives = 100/381 (26%), Gaps = 83/381 (21%)

Query: 76  GQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELAL-FSRVNGKFSTEFQ 134
           G +++P+    I      +   S  + ++       +   N    L     N  FS    
Sbjct: 60  GGFVVPNVSRDIKNSLVPIGRQSSGVRTFQEMVEYFNQKANLSGGLPLGCFNSAFS---- 115

Query: 135 RMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLA 194
                        T  +  +   +   +            LM     L +N  +      
Sbjct: 116 ------------FTGSKHIDAAVSKTLSMDGYYIPLAKVQLMRSPLVLHENVKRAVPTCW 163

Query: 195 E-----LLILNYGTHVITSVDAGAALVQEDHVRSS----------FLLDNQNSQNT---- 235
           +       I N+GTHVITSV  G   V       S          ++ D  N + +    
Sbjct: 164 DPPSLASFIENFGTHVITSVTIGGKDVIYVKQHQSSPLSTLEIKHYVQDIGNQRFSDMEG 223

Query: 236 --------VTASAGIAFLNIVNFKVETDYISQ----TSLTKDYLSNRTNSRVQSFGGVPF 283
                   +   A               + SQ       +  YL+ + +  V        
Sbjct: 224 HTSSGPMKLKDKASPRIFPYFFGGDSGIFNSQGIYPQPTSAPYLTGKEHVTVIFCRRGGD 283

Query: 284 YPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYT 343
                   W + + +    I+ + +P+   +           +     + +  A+  Y  
Sbjct: 284 DLEQNHIKWARTVQSSPDVIEMSFVPITDLL-----------VGAPGKEHLCRAIALYLE 332

Query: 344 FNT------------HPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGG----VYQEC-- 385
           +               P        NF       +  C      F+  G    V QE   
Sbjct: 333 YKPQIEELRYFLEFQIPRIWAPVQDNF-PGHQRKEPVC--PSLQFSMMGQKLYVSQEQIS 389

Query: 386 ---TELSGDVLCQNLEQKNLL 403
                ++G  LC    ++N L
Sbjct: 390 VGRKPVTGLRLCMEGAKQNRL 410


>UniRef50_Q7RHP1 Putative uncharacterized protein PY03943 n=3 Tax=Plasmodium
           (Vinckeia) RepID=Q7RHP1_PLAYO
          Length = 685

 Score = 54.5 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 38/260 (14%), Positives = 73/260 (28%), Gaps = 47/260 (18%)

Query: 130 STEFQRMKTLQVKDQAVTTRVQVRNRIY--TVKTTPTSELSLGFTKALMDIC-------- 179
           S+ + RM   +++        +     Y   +K    S+L   F   L D+         
Sbjct: 177 SSNYYRMLVERIEKGYSIIIDKKICSKYFVALKNVDNSKLDPFFISMLNDLEKNYNNINI 236

Query: 180 -------DQLEKNQTKMA----TYLAELLILNYGTHVITSVDAGAALVQEDHV------- 221
                     +KN+                  YGTH+++ V  G  ++   +        
Sbjct: 237 NKYKCGVHSYKKNKYDKNCLRTITPWITFFNLYGTHLVSEVYYGGKIINILYSDYYNNIN 296

Query: 222 RSSFLLDNQNSQNTVTA--SAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFG 279
            S  +   +   N  T+    G  +   +  K ++      +        +  + +   G
Sbjct: 297 DSEQVQIYKKRLNPFTSGNKLGSFYFGSIISKKQSSTNKNQNNDNMLTYIKEKNTIYDGG 356

Query: 280 ----------GVPFYPGITLETWQKGITNHLV-AIDRAGLPLHFFIKPDKLPGLPGPLVK 328
                     G         E W++ I       I     P   FIK D         ++
Sbjct: 357 IDIKEYKDGEGKVLMTNGIEEEWERTINGKYAKPIKLILRPFSDFIKTDDGKVAYYKALE 416

Query: 329 KLSKTVETAVRHYYTFNTHP 348
             S         Y+ +N +P
Sbjct: 417 YYSS------ITYFDYNKYP 430


>UniRef50_Q8IB29 MAC/Perforin, putative n=5 Tax=Plasmodium RepID=Q8IB29_PLAF7
          Length = 654

 Score = 54.5 bits (129), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 40/334 (11%), Positives = 87/334 (26%), Gaps = 58/334 (17%)

Query: 35  KNALKLPVLEVLPGGGWDNLRNVDM---GRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKE 91
            +     +     G G+D L    +     + D  +   +   D Q  I D +       
Sbjct: 32  TDEKTNEIFSKYLGKGYDILFGYPLPNNELIDDPGF--KEVIIDTQLSI-DNISNYI--- 85

Query: 92  SNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQ 151
              E   +V+E   +        IN +           S  ++         +      Q
Sbjct: 86  CKKEEYVDVIEDINDIGYLGMQKINIDDLDNRIKPFSASMPYKSYFADLEIKKKKYALAQ 145

Query: 152 VRNRI----YTVKTTPTSELSLGFTKALMDICDQLEKNQT--------------KMATYL 193
               +    Y +K +    ++  F   +  +    +                        
Sbjct: 146 NMCVLNYATYDLKESGN-NINKDFVLDIEKLPILTKNQMKLCTKVLYMNNNLHCSEGIKS 204

Query: 194 AELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNT--------VTASAGIAFL 245
                  YGTHV+ S   G        +    + + +  +          +      +  
Sbjct: 205 WMKFFEKYGTHVVLSAHFGGMSFNTMEITKRKIEEIKIYKYKYSLWNNPYLNIFKSGSLF 264

Query: 246 NIVNFKVETDYIS------------QTSLTKDYLSNRT-------NSRVQSFGGVPFYP- 285
             ++  V+    +            +      Y+ N         N  ++  GG  F   
Sbjct: 265 QDLSINVDGHKENKKNNSNNNINIDEKKKNDAYIKNDVLIEQYRDNINLEIRGGNNFDEK 324

Query: 286 --GITLETWQKGITNHLVAIDRAGLPLHFFIKPD 317
              +T   W+  I +++V I      L+ F+  +
Sbjct: 325 WRNLTYLVWKNSIYSNIVPIHLDLYSLNTFMPIE 358


>UniRef50_Q940R0 At1g29690/F15D2_24 n=1 Tax=Arabidopsis thaliana RepID=Q940R0_ARATH
          Length = 383

 Score = 54.1 bits (128), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 31/150 (20%), Positives = 47/150 (31%), Gaps = 21/150 (14%)

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
            I NYGTH++TSV  G   V       S  L     +N V       F        E + 
Sbjct: 177 FIENYGTHIVTSVTIGGRDVVYIRQHQSSPLPVSEIENYVNDMIKHRFH-------EAES 229

Query: 257 ISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKP 316
            S T   K Y         +  GG       +   W + +      I+    P+   +  
Sbjct: 230 QSITGPLK-YKDKDITVIFRRRGG--DDLEQSHARWAETVPAAPDIINMTFTPIVSLL-- 284

Query: 317 DKLPGLPGPLVKKLSKTVETAVRHYYTFNT 346
           + +PGL           +  A+  Y  +  
Sbjct: 285 EGVPGLW---------HLTRAIELYLEYKP 305


>UniRef50_D2VHQ5 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VHQ5_NAEGR
          Length = 457

 Score = 54.1 bits (128), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 37/279 (13%), Positives = 83/279 (29%), Gaps = 32/279 (11%)

Query: 61  RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELA 120
               + Y +   T   Q +  + V  +     N  ++  + ++   Y     +S      
Sbjct: 42  LFAGMGYDSYAHTVKPQILNSNTVNVLSSPSVN-SISVTMTDARQFYSQVYPISGQQSTF 100

Query: 121 LFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICD 180
                    +     + T   + +      Q +   +    T   +++ GF++ +  + +
Sbjct: 101 YNGLYT--HNGGADEIFTKFFEGKLNVLNAQQQYTTHQTSVTNAMDITSGFSRIVEILPN 158

Query: 181 QLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASA 240
                  +M   + E +I  +G  V+T V+ G  +     VR  +   N  +      S 
Sbjct: 159 -------EMNQEMYEKIIEFFGDSVMTLVNFGGVVDSTVSVRGCYSDPNMENYVKTQLSG 211

Query: 241 GIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHL 300
            I   +     V   +          +     S +   GG P    I      +    + 
Sbjct: 212 IIQGYD---ADVPVGW----------VKYHKISELDIAGGNPEIDNIPRR--VETFHLNP 256

Query: 301 VAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVR 339
           V I    +P+         P  P      +    ++ V+
Sbjct: 257 VPIRFDTIPIW-----QVFPEGP--KRNNMKAVYDSYVQ 288


>UniRef50_C3YPJ1 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3YPJ1_BRAFL
          Length = 1264

 Score = 54.1 bits (128), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 27/178 (15%), Positives = 49/178 (27%), Gaps = 47/178 (26%)

Query: 289 LETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHP 348
            E W + +  +   I     P+   +       +  P   +  + +E A+  Y   N++ 
Sbjct: 390 YEAWIQDVKRNPAIIRYEITPISELV-------VGIPQADRKRRNLEQALVDYL--NSYH 440

Query: 349 GCTNVDSPNFNFQANMDDDS-CDAKVTNFTFGGVYQECTEL--------------SGDVL 393
            C    SP  N    +   + C       TFG   ++ T++                   
Sbjct: 441 SC--KCSPCQNNGQALLIGTDCVCVCKAGTFGISCEQGTQIDNVGAAIHGNWACWGPWTA 498

Query: 394 CQNL-------------EQKNLLTGDFSCPP--------GYSPVHLLSQTHEEGYSRL 430
           C                       G  +CP          Y   +LL  TH+    + 
Sbjct: 499 CSAESDGSGQRTRQRTCTNPAPQNGGQACPGQDSETETCNYIAQNLLQGTHKLIKRQH 556


>UniRef50_A7S1Q6 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7S1Q6_NEMVE
          Length = 424

 Score = 53.7 bits (127), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 34/237 (14%), Positives = 61/237 (25%), Gaps = 36/237 (15%)

Query: 100 VLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTL---------QVKDQAVTTRV 150
            + S   +    +   N E  L      K + +   +            Q   +  T  +
Sbjct: 74  FIRSKTAFYRLLAERFNIESDLVGDYFFKATEQSLFLLRHGESMMGTIEQFFKKTSTRVI 133

Query: 151 QVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVD 210
                         + LS G      ++  ++ K +   +    +  I  YGTHVI SV 
Sbjct: 134 TRSCLR-------DASLSEGIENDFKNLPAKISKPKHAKSWDSYKNFITKYGTHVIKSVS 186

Query: 211 AGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNR 270
            GA  +       +    +Q    ++                       TSL        
Sbjct: 187 YGAKFL-IFAFAKASKNYSQKDFKSIVCK-----FMKDGPDCRVTSEIDTSLLDIKQ--- 237

Query: 271 TNSRVQSFGGV--------PFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKL 319
               V + GG                ++      T H V +      +   +K   L
Sbjct: 238 ---IVIAIGGSKESRQALITSPNKKAIDKLMSEATEHAVPVSYEFEAIWNILKLKFL 291


>UniRef50_B6TJS6 MAC/Perforin domain containing protein n=4 Tax=Magnoliophyta
           RepID=B6TJS6_MAIZE
          Length = 558

 Score = 53.3 bits (126), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 28/150 (18%), Positives = 42/150 (28%), Gaps = 21/150 (14%)

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
            I NYGTH+I SV  G      D V       +Q S+      A            + + 
Sbjct: 178 FIENYGTHIIISVTVGGK----DEVYIKQHSLSQLSELEFKNYAREIGRERF---ADVEN 230

Query: 257 ISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKP 316
            S  S   +Y         +  GG           W+  + +    I    L +   +  
Sbjct: 231 KSNASSI-NYSEKDMTVIFRRRGGCDLVQSF--SDWRGTVASAPDVIGITFLSIVSLVDD 287

Query: 317 DKLPGLPGPLVKKLSKTVETAVRHYYTFNT 346
                          K +  AV  Y T+  
Sbjct: 288 -----------IPGKKHLARAVELYLTYKP 306


>UniRef50_A7S919 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
           RepID=A7S919_NEMVE
          Length = 367

 Score = 53.3 bits (126), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 26/163 (15%), Positives = 43/163 (26%), Gaps = 13/163 (7%)

Query: 164 TSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRS 223
             + +         +   + K    ++    E  +  +GTHV+TS   G+ + Q    R 
Sbjct: 112 EPKFTADLLGRFKALPSTVPKPYKSVSWTEYEDFVKRFGTHVVTSALLGSFICQYAFARG 171

Query: 224 SFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPF 283
                       V A A     +     +                   NS+    GG   
Sbjct: 172 D--KRYSMDDLKVKACA---LFSKDPDGIPACRRVTEDQLGKVNGMEMNSKTVIRGGTVD 226

Query: 284 --------YPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDK 318
                        LET++    N    I     PL   +K   
Sbjct: 227 TRSKLLFSRTKELLETFKSEAKNSTSPISYILSPLWRLLKMKF 269


>UniRef50_Q9SGN6 F3M18.18 n=37 Tax=Magnoliophyta RepID=Q9SGN6_ARATH
          Length = 612

 Score = 53.3 bits (126), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 49/306 (16%), Positives = 93/306 (30%), Gaps = 57/306 (18%)

Query: 48  GGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYII------------PDEVYTIPQKESNLE 95
           G G+D           D+ ++ CKTT DG  ++            P  +       S   
Sbjct: 23  GLGYD--------LCSDVRFSACKTTPDGSRLVEIDPTRNRDLIFPGGIVVNNVSSSIKC 74

Query: 96  MNSEVLESWMNYQS--TTSLSINTELALFSRV-NGKFSTEFQRMKTLQVKDQAVTTRVQV 152
              E      +  S    S   N ++ L  ++ +G F+  F   K       +V T    
Sbjct: 75  DKGERTRLRSDILSFNQMSEKFNQDMCLSGKIPSGMFNNMFAFSKCWPKDASSVKTLAYD 134

Query: 153 RN--RIYTVKT-TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSV 209
                +Y+V+       L     + +       +              I  YGTHV+  V
Sbjct: 135 GWFISLYSVEIVRKQLTLRDEVKREV---PSSWDSAA-------LAGFIEKYGTHVVVGV 184

Query: 210 DAGAA-LVQEDHVRSSFLLDNQNSQ------------NTVTASAGIAFL-------NIVN 249
             G   ++    +R S     +  +            + V + +  +         N++ 
Sbjct: 185 TMGGKDVIHVKQMRKSNHEPEEIQKMLKHWGDERFCVDPVESKSPASVYSGKPKEENLLQ 244

Query: 250 FKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLP 309
           + ++    S +S    +  N    RV    G     G + E W   ++     I    +P
Sbjct: 245 WGLQPFGTSVSSAVVMHTKNEEIMRVCIRRGGV-DLGQSHERWLSTVSQAPNVISMCFVP 303

Query: 310 LHFFIK 315
           +   + 
Sbjct: 304 ITSLLS 309


>UniRef50_D1HA82 Whole genome shotgun sequence of line PN40024,
           scaffold_58.assembly12x (Fragment) n=1 Tax=Vitis
           vinifera RepID=D1HA82_VITVI
          Length = 623

 Score = 52.6 bits (124), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 41/282 (14%), Positives = 71/282 (25%), Gaps = 51/282 (18%)

Query: 89  QKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVN-GKFSTEFQRMKTLQVKDQAVT 147
            K S  E     +   +++        N +  L   V  G F+  F     L+  D A T
Sbjct: 107 IKNSQ-ETKGREISGVLSFPEMVEYF-NKKANLSGNVPLGSFNAAF-SFTGLKHMDSATT 163

Query: 148 TRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAE-----LLILNYG 202
                            +         L++    L++N  +      +       I N+G
Sbjct: 164 K-----------SLYMDAFFISLAKVQLVNSPLVLQENVKRAVPSCWDPPSLASFIENFG 212

Query: 203 THVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSL 262
           THVITSV  G   V       S  L     +N V       F +  +         +   
Sbjct: 213 THVITSVTIGGKDVIYVKQHQSSPLSTMEIKNYVQDIGNQRFSDTESNASSGPMKLKDKS 272

Query: 263 TKDYL------------------SNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAID 304
               L                          +  GG       +   W   + +    I+
Sbjct: 273 VDPCLFNSQGIYPQPTSAPILTGKEDVTVIFRRRGG--DDLEQSHTQWATSVRSSPDVIE 330

Query: 305 RAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNT 346
               P+   +                 + +  A+  Y  +  
Sbjct: 331 MTFFPITALL-----------EGVTGKEHLAHAIGLYLEYKP 361


>UniRef50_B2AFJ9 Predicted CDS Pa_5_11830 n=1 Tax=Podospora anserina
           RepID=B2AFJ9_PODAN
          Length = 612

 Score = 52.6 bits (124), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 33/217 (15%), Positives = 64/217 (29%), Gaps = 19/217 (8%)

Query: 90  KESNLEMNSEVLESWMNYQ-STTSLSINTELALFS---RVNGKFSTEFQRMKTLQVKDQA 145
           K +  E  +    S      S+T++  N   + F      +   S E    K    ++  
Sbjct: 274 KVTVTETRTAFQRSMAREGFSSTAIEANASGSPFGKSISASAALSDENSYSKKSLTEETD 333

Query: 146 VTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTK-MATYLAELLILNYGTH 204
            T  V  +     +      +LS  + +    + D+ E+      + Y     I +YG  
Sbjct: 334 FTLEVAYKFPRVAI------DLSPRYLQ----LSDECEEAIKNIKSDYDKVQFINDYGDA 383

Query: 205 VITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLN---IVNFKVETDYISQTS 261
             T V  G  L     V          ++     +AG++F +                T+
Sbjct: 384 FPTKVVLGGFLRSSRQVIVKTNEQLDAAKEETKKAAGLSFASPQVSFGVNYAKTTSDTTT 443

Query: 262 LTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITN 298
            T+           ++ GG           W   + +
Sbjct: 444 TTQGQTIGNAALTWEARGGDTVLCS-NPSAWASTVKD 479


>UniRef50_C7XDV3 Predicted protein n=1 Tax=Parabacteroides sp. D13
           RepID=C7XDV3_9PORP
          Length = 746

 Score = 52.2 bits (123), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 36/253 (14%), Positives = 66/253 (26%), Gaps = 34/253 (13%)

Query: 125 VNGKFSTEFQRMKTLQVKDQA-----VTTRVQVRNRIYTVKTTPTSEL-------SLGFT 172
            +G F+  FQ  +T   + +      V   V++        T    ++       +  F 
Sbjct: 260 FSGSFNERFQHNRTSSNRFEYHVDVHVKPMVELHMATAIYTTDNDPDVFLPYLTATAQFL 319

Query: 173 KALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNS 232
             +           TK   Y    L   YGTHV+     G +       + +   D    
Sbjct: 320 LNVSHDDLYKRYPNTKEGIYD---LYDTYGTHVLVGGVFGGSYTYIYSRKENMYYDETVL 376

Query: 233 QNTVTASAGIA------------FLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGG 280
                 SA  A            +  ++                +   + +   +    G
Sbjct: 377 AAEAELSAKSASPAGENENWLQTYYRVMGTHGGKIGAGGGYTKSELNEHMSEESIMIITG 436

Query: 281 VPFYPGITLETWQKGITN-----HLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVE 335
                 +  E+W   I +     HLV     G   + F+ P             L + + 
Sbjct: 437 G--NASVDFESWDNSIADENSNLHLVRYGPKGDSTNCFMIPLYYLTKDSARKNALKEHLN 494

Query: 336 TAVRHYYTFNTHP 348
             V  +      P
Sbjct: 495 AYVEEHSKLEKEP 507


>UniRef50_Q9LQV3 F10B6.18 n=3 Tax=rosids RepID=Q9LQV3_ARATH
          Length = 645

 Score = 51.8 bits (122), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 48/281 (17%), Positives = 76/281 (27%), Gaps = 55/281 (19%)

Query: 94  LEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVR 153
               SE      +       S N     F   +G ++T+   +K+L +    VT      
Sbjct: 86  FNKMSEYFNQRSSVTGKI-PSGNFNAT-FGFQSGSWATDAANVKSLGLDASVVTL----- 138

Query: 154 NRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGA 213
              + +     + L    T  + +        Q      L    I  YGTHVIT V  G 
Sbjct: 139 ---FNLHIHNPNRL--RLTDRVRNAVPSSWDPQ------LLARFIERYGTHVITGVSVGG 187

Query: 214 ALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLN--------------------IVNFKVE 253
             V       S  LDN   ++ +       F                             
Sbjct: 188 QDVVVVRQDKSSDLDNDLLRHHLYDLGDQLFTGSCLLSTRRLNKAYHHSHSQPKFPEAFN 247

Query: 254 TDYISQTSLTKDYLSNRTNSRVQS---FGGVPFYPGITLETWQKGITNHLVAIDRAGLPL 310
                QT    ++  N  N         GG       +   W   + +   AI+   +P+
Sbjct: 248 VFDDKQTVAFNNFSINSQNGITVICAKRGGDGRAK--SHSEWLITVPDKPDAINFNFIPI 305

Query: 311 HFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCT 351
              +K     GL           +  A+  Y   N +  C 
Sbjct: 306 TSLLKDVPGSGL-----------LSHAMSLYLRCN-YSSCL 334


>UniRef50_UPI00006A1BED UPI00006A1BED related cluster n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI00006A1BED
          Length = 335

 Score = 51.4 bits (121), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 40/253 (15%), Positives = 81/253 (32%), Gaps = 24/253 (9%)

Query: 90  KESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNG-KFSTEFQRMKTLQVKDQAVTT 148
           ++       E++   +  +   SLS +   A          S+E   +     +   V T
Sbjct: 3   QKEFTCHEEELVFQRIVEKIGLSLSGSITAAFLGFGPRDSKSSESDTISKQPSEHVYVCT 62

Query: 149 RVQVRNRIYTVKTTPT-SELSLGFTKALMDICDQLEKNQTKMA-TYLAELLILNYGTHV- 205
                  + +   T     LS     AL  I   +  N T+            ++G+HV 
Sbjct: 63  TRYNFIPLASCHFTEDQLRLSEPALNALKFIEKLITNNSTEQMLATKCAEFFQSFGSHVN 122

Query: 206 ITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVE------TDYISQ 259
           +  +  G  L  +  +    + D +N++  ++ +    F   V +         +   SQ
Sbjct: 123 LGPIHFGGILWWKASMEGGEVGDLRNAKEMISEALN--FYASVGYDGSERDIDLSAIDSQ 180

Query: 260 T----SLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGI-----TNHLVAIDRAGLPL 310
           +    S    +      S  ++ GG       +L  W+ GI     T  ++      +P+
Sbjct: 181 SSMDLSKISTFKEYIQVSVTKT-GGP--SEADSLSQWKTGIVTSEKTWSVIDRGFQLMPI 237

Query: 311 HFFIKPDKLPGLP 323
              I  +     P
Sbjct: 238 WKIIVDNHKDEFP 250


>UniRef50_UPI0001983FB0 PREDICTED: hypothetical protein n=2 Tax=Vitis vinifera
           RepID=UPI0001983FB0
          Length = 1169

 Score = 51.4 bits (121), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 29/150 (19%), Positives = 48/150 (32%), Gaps = 21/150 (14%)

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
            I NYGTH++TS   G       +VR   L    +S             +I + +     
Sbjct: 186 FIENYGTHIVTSATIGGR--DVVYVRQHQLSPLSSSD------IENYVKDIGDQRFLDPK 237

Query: 257 ISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKP 316
              T+    Y         +  GG       +   W + +      I+   +P+   +  
Sbjct: 238 SQPTAAPLKYKDKDVTVIFRRRGG--DDLEQSHAKWSETVELAPDVINMKFVPIVSLL-- 293

Query: 317 DKLPGLPGPLVKKLSKTVETAVRHYYTFNT 346
           D +PGL         K +  AV  Y  +  
Sbjct: 294 DSVPGL---------KHLARAVDLYLEYKP 314


>UniRef50_D1IBJ9 Whole genome shotgun sequence of line PN40024,
           scaffold_3.assembly12x (Fragment) n=1 Tax=Vitis vinifera
           RepID=D1IBJ9_VITVI
          Length = 1252

 Score = 51.4 bits (121), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 29/150 (19%), Positives = 48/150 (32%), Gaps = 21/150 (14%)

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
            I NYGTH++TS   G       +VR   L    +S             +I + +     
Sbjct: 186 FIENYGTHIVTSATIGGR--DVVYVRQHQLSPLSSSD------IENYVKDIGDQRFLDPK 237

Query: 257 ISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKP 316
              T+    Y         +  GG       +   W + +      I+   +P+   +  
Sbjct: 238 SQPTAAPLKYKDKDVTVIFRRRGG--DDLEQSHAKWSETVELAPDVINMKFVPIVSLL-- 293

Query: 317 DKLPGLPGPLVKKLSKTVETAVRHYYTFNT 346
           D +PGL         K +  AV  Y  +  
Sbjct: 294 DSVPGL---------KHLARAVDLYLEYKP 314


>UniRef50_Q23JP5 MAC/Perforin domain containing protein n=13 Tax=Tetrahymena
           thermophila SB210 RepID=Q23JP5_TETTH
          Length = 530

 Score = 51.4 bits (121), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 28/273 (10%), Positives = 75/273 (27%), Gaps = 50/273 (18%)

Query: 74  EDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQST-TSLSINTELALFSRVNGKFSTE 132
              Q+I+ DE      ++ NL+ +  V ++     +     + N +      + G++S  
Sbjct: 119 SSRQFIVADET---SIEQVNLDADIRVFKNEFELTNIWLDATQNGQW-----LGGEYSQS 170

Query: 133 FQRMKTLQVKDQAVTTRVQVRNRIYTVKTT---PTSELSLGFTKALMDICDQLEKNQTKM 189
                               +     ++ T    + +L+    +A+  +           
Sbjct: 171 KDLNDVYTRFFTNNQQTSIAQQSKNVIRMTFKTDSLKLNRFAQRAIDALP-------EDY 223

Query: 190 ATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQ----NTVTASAGIAFL 245
              +    +  +GTH+      G  + ++   +       Q +       V  +      
Sbjct: 224 QVDVYNEFLNAWGTHISVDTFVGGMIEKQTVFKDCVFFTPQFTGGYSAEQVNEALRNELQ 283

Query: 246 NIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDR 305
                               + + R  +    FGG P      +  W++ I+ +   +  
Sbjct: 284 GNPAEGF-------------FTARRQVTLDHKFGGNP----EDVANWEQTISQNPALLKI 326

Query: 306 AGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAV 338
                        L         ++   ++ A+
Sbjct: 327 N----------RFLSWDNMAANPQVKANLQQAI 349


>UniRef50_B3L199 MAC/perforin, putative n=1 Tax=Plasmodium knowlesi strain H
           RepID=B3L199_PLAKH
          Length = 685

 Score = 51.0 bits (120), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 46/355 (12%), Positives = 93/355 (26%), Gaps = 72/355 (20%)

Query: 43  LEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLE 102
                G G+D L    +    +L        E       + +  I Q   + +     +E
Sbjct: 53  FSKYIGKGYDILFGYPL-PNNELVEDPGFRNEIFDTR--NSLDIINQVACHRDEYFNFVE 109

Query: 103 SWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNR----IYT 158
              +       +IN E    S +    S  ++         +     VQ         Y 
Sbjct: 110 GINDVTHLAMDNINVEDVNSSVIPFSASMPYKSYFADLEIGRKKYLVVQNNCVHKYVTYN 169

Query: 159 VKTTPTSELSLGFTKALMDICDQLEKNQTKM---ATYL--------------AELLILNY 201
           ++   T  ++  F      +    +K+  K      Y                      Y
Sbjct: 170 LR-DTTRHINREFLLETDKLPILEKKDNQKECLKGRYRHSGKNERCAEIIKPWIDFFKKY 228

Query: 202 GTHVITSVDAGAALVQEDHVRSSFLLDNQN----------SQNTVTASAGIAFLNIVNFK 251
           GTH++ S   G        V    + + +           +   V  +A +   +     
Sbjct: 229 GTHLVLSAHFGGQSFNSLEVSRRTMEEAKIYSYKYPLSNVTNLDVFRTALLLQGDTKEAG 288

Query: 252 VETDYISQTSLTKDYLS----------------------NRTNSRVQSFGGVPFYPG--- 286
            + +           L                           + + + GG   Y G   
Sbjct: 289 KDGNVSDVRRGRDHILKDPHNELHDEPLNEPPRMREKSMGEKTASLDTRGGNQTYNGWKQ 348

Query: 287 ITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHY 341
            T   W+  I  +L+ +    + L  F++            K+  ++ E A+ +Y
Sbjct: 349 QTYAVWKDSIYANLLPVHLDLISLSSFMR------------KEKKESYEKALVYY 391


>UniRef50_D2UX93 Membrane-attack complex/perforin domain-containing protein n=1
           Tax=Naegleria gruberi RepID=D2UX93_NAEGR
          Length = 644

 Score = 51.0 bits (120), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 34/266 (12%), Positives = 82/266 (30%), Gaps = 34/266 (12%)

Query: 77  QYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRM 136
            + I  ++   PQ +   +  ++ L    + +         +           ++    +
Sbjct: 93  DHTIKPQIVKSPQAKKVTQTVTKFLNVMDSAERFFDYVYPGDGVPIYNGLYSHNSGAAEI 152

Query: 137 KTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAEL 196
            T   K   +    Q +   + V      E++  F + L  +   L+++       L  L
Sbjct: 153 FTNYFKGNMMVMDAQQQYVTHAVSV-DKVEVTEDFQRILDILPSTLDRD-------LYNL 204

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
           +I ++G  ++  V+ G  +     VRS F   N  +   +                    
Sbjct: 205 VISSFGDSILYQVEYGGVVDLTVSVRSCFNDANMKNYLDLELQMAA-------------G 251

Query: 257 ISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKP 316
            +  +L   Y+     S++   GG P      ++      + + V +    +P+      
Sbjct: 252 DAPNTLPSGYIRYHKVSQLDIVGGNPELS--DIKQRVNTFSLNPVPVKFLSVPIW----- 304

Query: 317 DKLPGLPGPLVKKLSKTVETAVRHYY 342
              P  P        + ++   + Y 
Sbjct: 305 RAFPNGP------KQENMKKVYQEYL 324


>UniRef50_C3ZMB3 Putative uncharacterized protein n=5 Tax=Branchiostoma floridae
           RepID=C3ZMB3_BRAFL
          Length = 1592

 Score = 50.6 bits (119), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 44/289 (15%), Positives = 75/289 (25%), Gaps = 94/289 (32%)

Query: 76  GQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQR 135
            ++ +PD +      +   +M S    S   Y+S                          
Sbjct: 221 KEFHVPDTMTVQGIYD--TDMESYTFSSLEEYRSYL------------------------ 254

Query: 136 MKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLA- 194
                 +D++  T  +                   F + +      L         + A 
Sbjct: 255 ------EDKSAVTSAKSI-----------------FQQEMDKAQGHLAGGGAFGLIWSAG 291

Query: 195 -ELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFK-- 251
            E  IL +GTH ITS   G   ++    R + + D+Q S      S      +  + +  
Sbjct: 292 GENFILRWGTHYITSAKFG-RQLKIIKTREASVTDSQESFAKAAQSDFHKLFSTYSAQQT 350

Query: 252 -------------------VETDYISQTSLTKDYLSNRTNSRVQ-------SFGG----- 280
                                    S+TS           S+ Q         GG     
Sbjct: 351 QTKSSSFWHDSESTEESSSSSGQGNSETSSEDALSEKAALSQTQYSNEVMEVQGGDQKIA 410

Query: 281 ---VPFYP---GITLETWQKGITNHLVAIDRAGLPLHFFIK---PDKLP 320
                FY    G +L+ W + I     A +   LP+   +        P
Sbjct: 411 AAITEFYTTSFGNSLKDWLESIEEFPKAFEFRMLPITDLLDMNYDSFFP 459


>UniRef50_UPI0001554DA0 PREDICTED: similar to Complement component 7, partial n=1
           Tax=Ornithorhynchus anatinus RepID=UPI0001554DA0
          Length = 646

 Score = 50.6 bits (119), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 48/331 (14%), Positives = 86/331 (25%), Gaps = 62/331 (18%)

Query: 103 SWMNYQSTTSLSINTELALFSRVNG-KFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKT 161
           S+  Y S+ +   +++ +  S     K +       +   +   V   V+V    +    
Sbjct: 54  SYEFYNSSWAYVKHSQTSFTSNTGTRKMNQNVNNNNSKSSQIMVVQNSVEVAQ--FINNR 111

Query: 162 TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHV 221
                L+  F K L  +    E +           LI  YGTH + S   G       +V
Sbjct: 112 PEFLTLAEPFWKELSHLPSVYEYSA-------YRRLIEQYGTHYLQSGSLGGQYKVLFYV 164

Query: 222 RSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGV 281
            +  +     +   +       +       V       T L      +       S GG+
Sbjct: 165 DTEKMKREGFNILHMKECVTSGWSLFF---VRKKKTECTKLEDVLKWSSDPDLGVSEGGL 221

Query: 282 PFYPGITLE------TWQKGITNHLVAIDRA-----GLPLHFFIKPDK------------ 318
              PG  L        ++  +         +     G P      P              
Sbjct: 222 SAGPGKPLRPVSPGPAFRSEVPVSPAPPGSSGNELRGDPYIEGGNPAFVAGLSYLDLNNP 281

Query: 319 ----------------LPGLPGPLVKKLSKTVE----TAVRHYYTFNTHPGCTN-----V 353
                            P +    +  LS+ V+     AV+   +   H G         
Sbjct: 282 AGNSARYSSWAGSVKDFPYIIKQKLAHLSELVKEVPCEAVKRAVSEARHRGVLQEQDPCR 341

Query: 354 DSPNFNFQANMDDDS-CDAKVTNFTFGGVYQ 383
             P  N    +   + C      +TFG   +
Sbjct: 342 CQPCQNGGEPIVLGTNCHCSCRPYTFGPACE 372


>UniRef50_UPI0001969EAD hypothetical protein BACCELL_05502 n=1 Tax=Bacteroides
           cellulosilyticus DSM 14838 RepID=UPI0001969EAD
          Length = 476

 Score = 49.9 bits (117), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 60/378 (15%), Positives = 113/378 (29%), Gaps = 73/378 (19%)

Query: 2   NSFMALVLIWMIIACAEAD--KPLGE-TGTTGFQICKNALKLPV-LEVLP-------GGG 50
           N F  ++ I  + AC+      P  E   ++ F   K      V  +  P       G G
Sbjct: 3   NLFYFIISICTLYACSSDSDFNPEDENPTSSDFYELKAIPDKKVIFKAYPANMKQILGAG 62

Query: 51  WDNLRN-VDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQS 109
           +D   + +    +        K          DE Y    K ++ E      E+   + +
Sbjct: 63  YDVTADHLSPEAIKAPIIDLEKLEN------SDEDYIYRMKATSSEPRDYAGENATTFLT 116

Query: 110 TTSLS-----INTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTR---VQVRNRI---YT 158
             + S     IN+  AL      K   EF+       +    ++       R      YT
Sbjct: 117 DITNSLILGDINSRNALSVGTILKH-KEFESDYNHSSQYSFASSEQLFTAERWYFSFFYT 175

Query: 159 VKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAAL--V 216
           ++      L+  F   +  +               AE +I  YGTH++  V  GA    +
Sbjct: 176 LEKYKYRYLTQEFENDVTSLA--------------AEDIINKYGTHLLVDVGIGARFRGL 221

Query: 217 QEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY------ISQTSLTKDYLSNR 270
               V ++    +      ++A   I    +        +           L  ++    
Sbjct: 222 YRTAVPTATSATSTTKITLLSALEKIGQQGLFTGSGAGGWEEEVAQSIGGQLILEFYGGN 281

Query: 271 TN---SRVQSFGGVPFYPGITLETWQ-KGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPL 326
           T+   S+  + G   ++     + +    IT + V      LP++  I            
Sbjct: 282 TSLLTSQPITDGFNAWWNSFNEKNYTLTKITQNKV------LPIYELIADATKKEQ---- 331

Query: 327 VKKLSKTVETAVRHYYTF 344
                  V+ A+  Y + 
Sbjct: 332 -------VKDAIEKYISN 342


>UniRef50_A1CVR0 Putative uncharacterized protein n=1 Tax=Neosartorya fischeri NRRL
           181 RepID=A1CVR0_NEOFI
          Length = 764

 Score = 49.1 bits (115), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 41/273 (15%), Positives = 89/273 (32%), Gaps = 32/273 (11%)

Query: 77  QYIIPDE--VYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQ 134
           ++++ D+  +     K S  +  ++   S   +    S  ++     F    G     ++
Sbjct: 308 RFLVQDDSYINVSENKTSVADAIAD--SSLSEH----SAEVSVGGGAFGVTAG-VKVGYK 360

Query: 135 RMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLA 194
                  + +  T      +      T     + L      +DI D+ +K+   ++T  A
Sbjct: 361 S------QAEVKTASNTTSDSKRMTITYNFPRVVLELDGDSLDISDECKKDLENISTPEA 414

Query: 195 ELLILN-YGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIV---NF 250
                  YGT   + V+ G  L   +   S      +     +  SA  +F +     + 
Sbjct: 415 VQFFRRKYGTFFASRVELGGRLHSSESSDSFAEGKVEERARALKISAAASFSSTYVQGSA 474

Query: 251 KVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGI---------TLETWQKGITNHLV 301
               +  S  S  +   S  TN   ++ GG                +   W+    + L+
Sbjct: 475 SGSYEDSSNHSSNRQNSSLSTNLAWEAKGGDTLLCNNPPAWCATVASYYNWRISKQDDLL 534

Query: 302 AID--RAGLPLHFFIKPDK--LPGLPGPLVKKL 330
           +++   + +P + ++K     L  L    V K 
Sbjct: 535 SMEDMISLIPGYEYVKQKFNNLAPLKESEVTKK 567


>UniRef50_B9N3I8 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
           RepID=B9N3I8_POPTR
          Length = 563

 Score = 48.7 bits (114), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 45/295 (15%), Positives = 84/295 (28%), Gaps = 39/295 (13%)

Query: 48  GGGWDNLRNVDMG----RVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLES 103
           G G+D  +++ +      +          T + + ++P  V              E    
Sbjct: 11  GFGYDLTKDIRLSYCKPGLFGSRLIKLDLTRNQELVVPGGVVVQNVPNGIKCDKGERTRF 70

Query: 104 WMNYQS--TTSLSINTELALFSRV-NGKFSTEFQRMKTLQVKDQAVTTRVQVRN--RIYT 158
             +  S    S   N EL L  ++ +G F+T F    + Q    +  +         +Y 
Sbjct: 71  LSDVLSFNQMSEKFNQELCLSGKIPSGLFNTMFNFRGSWQKDAASAKSLAFDGWFITLYN 130

Query: 159 VKT-TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQ 217
           ++       LS    + +           T          I  YGTH++  V  G   V 
Sbjct: 131 IELERSHITLSEKVKREV----------PTTWDPVALAEFIEKYGTHIVVGVRMGGKDVI 180

Query: 218 EDHVRSSFLLDNQNSQNTVTASAGIAFLNIV-----------------NFKVETDYISQT 260
               +    L+    Q  +   A   F   V                 +F     +  + 
Sbjct: 181 HMKQQQKSNLEPPEVQKLLKEYADKLFFGDVDPAELSGKPKDEHVMPWDFNGVFAHSMRP 240

Query: 261 SLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIK 315
            +     +    S     GGV    G +   W   I+     I  + +P+   + 
Sbjct: 241 PVITSIKNEDITSICIRRGGV--DVGQSHNQWLPTISQSPNVISMSLVPITSLLN 293


>UniRef50_A5K5Q5 MAC/Perforin domain containing protein n=1 Tax=Plasmodium vivax
           RepID=A5K5Q5_PLAVI
          Length = 668

 Score = 48.3 bits (113), Expect = 0.001,   Method: Composition-based stats.
 Identities = 47/371 (12%), Positives = 93/371 (25%), Gaps = 89/371 (23%)

Query: 43  LEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLE 102
                G G+D L    +    +L        E       + +  I Q   + +     +E
Sbjct: 27  FSKYVGKGYDILFGYPL-PNNELVEDPGFRNEIFDTR--NSLDIISQVACHRDEYFSFIE 83

Query: 103 SWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNR----IYT 158
              +       +IN E    S +    S  ++         +      Q         Y 
Sbjct: 84  GINDVAHLAMDNINVEDVNTSIIPFSASMPYKSYFADLEIGRKKYLVAQNSCVHKYVTYN 143

Query: 159 VKTTPTSELSLGFTKALMDICDQLEKNQTK---MATYL--------------AELLILNY 201
           ++   T  ++  F      +    +K   K      Y                      Y
Sbjct: 144 LR-DSTRHINREFLLETEKLPILEKKANGKDFLQGEYPHREGNQQCAGSIKPWMDFFQKY 202

Query: 202 GTHVITSVDAGAALVQEDHVRSSFLLDNQN--------------------------SQNT 235
           GTH++ S   G        V    + + +                            +  
Sbjct: 203 GTHLVLSAHFGGRSFNALEVSRRTMEEAKIYSYKYALGSVPSLDVFRAAWLQQGGPKRGG 262

Query: 236 VTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTN----------------------S 273
              SAG +   + +        S  S   D L+   N                       
Sbjct: 263 TEGSAG-SVDGVDSVDGIDSVDSVASGGDDILNQPNNQLHDQPLNQPPRTRENALGGRAP 321

Query: 274 RVQSFGGVPFYPG---ITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKL 330
            + + GG   + G   +T   W+  I  +L+ +    + L  F++               
Sbjct: 322 SLDTRGGNQTFDGWNQLTYAVWKDSIYANLLPVHLELISLSSFMR------------TGK 369

Query: 331 SKTVETAVRHY 341
            ++ + A+ +Y
Sbjct: 370 KESYDKALVYY 380


>UniRef50_UPI000023E855 hypothetical protein FG01821.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023E855
          Length = 817

 Score = 48.3 bits (113), Expect = 0.001,   Method: Composition-based stats.
 Identities = 47/313 (15%), Positives = 101/313 (32%), Gaps = 27/313 (8%)

Query: 86  TIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQ-VKDQ 144
            +P    N     +V+ S   +Q++ + +  +  +  + + G +      +   Q     
Sbjct: 160 VLPDFSVNDNSRIDVVVSSHEFQTSMATNDFSASSTSASLGGSYGPISASVSYSQDSMHS 219

Query: 145 AVTTRVQVRNRIYTVKTTPTSELSLGFTKAL---MDICDQLEKNQTKMATYLAELLILNY 201
           + T+          +       + L   + L     +   ++K +          L  +Y
Sbjct: 220 SSTSNTSDTYHKTMIAKYLFPRVDLSLDECLEPTDGLMKAIQKVEATKNIKDLRQLRQDY 279

Query: 202 GTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTS 261
           G    TS+  G  L  +  +  +     Q  + ++  S G++  +         +  ++ 
Sbjct: 280 GYLFCTSLTIGGRLQTQSIMTDTEKTSEQEQKQSMKTSVGLSVASP-EASASISHTQESG 338

Query: 262 LTKDYLSNRT----NSRVQSFGGVPFYPGITLETWQKGI--TNHLVAIDRAGLPLHFFIK 315
                    +    +   ++ GG        L  W   +   N+   I+R GL     + 
Sbjct: 339 SANSQSQATSDKYESHAFEAMGGDTLLASNPLS-WIPTVGNYNNWRIINRDGL----ILM 393

Query: 316 PDKLPGLPGPLVKKLSKTVETAV---RHYYTFNT---HPGCTNVDSPNFNFQANMDDDSC 369
            D + GL G  ++ +    E AV     Y  F+          + SPN N   +    S 
Sbjct: 394 SDMISGLSG--LEHVRSWFEQAVPTSSKYIEFSDKLVKKIRLRLMSPNHNLCLSYKSGSD 451

Query: 370 DAKVT---NFTFG 379
           +       N+ FG
Sbjct: 452 EEDFAFPPNYYFG 464


>UniRef50_A6G7F3 Hemopexin n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G7F3_9DELT
          Length = 516

 Score = 47.9 bits (112), Expect = 0.001,   Method: Composition-based stats.
 Identities = 29/223 (13%), Positives = 60/223 (26%), Gaps = 22/223 (9%)

Query: 102 ESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKT 161
           ESW  +  + +L         +      S     +++         +       +Y    
Sbjct: 88  ESWERFSRSRALDYGLAAGWMTFNVDASSHLGNELRSDHESYYGSRSSFVALWSVY---- 143

Query: 162 TPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHV 221
                        + D+         +      E     YGTH +     G        V
Sbjct: 144 LEDPSQPTHALP-VDDLPAPYSPAHRR----AYEAFFDRYGTHFVKRAWVGGKA----EV 194

Query: 222 RSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGV 281
                   + S+  + A    +F  I+          + S +++ L +R    V   GG 
Sbjct: 195 LFCVAKSGKMSREDIYAGLRASF--ILPNSPSPKVGRELSRSQEALMSRAQCTVVGRGGD 252

Query: 282 -------PFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPD 317
                      G T + W K I ++   ++     +   +  +
Sbjct: 253 ELALASLSSLDGGTYDAWLKTIKDNPQTVELGLAGIWTLVVDE 295


>UniRef50_B3C689 Putative uncharacterized protein n=4 Tax=Bacteroides
           RepID=B3C689_9BACE
          Length = 559

 Score = 47.6 bits (111), Expect = 0.002,   Method: Composition-based stats.
 Identities = 32/251 (12%), Positives = 77/251 (30%), Gaps = 28/251 (11%)

Query: 90  KESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTE-FQRMKTLQVKDQAVTT 148
           + S    +      + +   T     +  L  FS    K +TE F+       +      
Sbjct: 127 QSSFAYYDFNNYTHFSSISKTVKSGFSLNLGFFSIGKKKTTTETFRTFINESKEQAYGEM 186

Query: 149 RVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITS 208
            +   +  +T+ ++  S  +  F +    +      N           +I +YG  V+  
Sbjct: 187 NILFAHGKFTLLSSNGS--NKVFARQF--LRRSFINNLYTSP---ISSIIDSYGDFVVVG 239

Query: 209 VDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFL---NIVNFKVETDYISQTSLTKD 265
              G     +    +    + +    ++  +   + +   + +N     +    T  +  
Sbjct: 240 YYTGGRAFAQYMGNADSNTNVEQKTKSLEKNINASLVYKGDSLNGSFGFNGKDGTFDSTV 299

Query: 266 YLSNRTNSRVQSFGGVPF------------YPGITLETWQKGITNH-----LVAIDRAGL 308
           Y       RV++ GG+                 I L++W+K + +      +  I+    
Sbjct: 300 YKRQDIFIRVKTLGGIQDETGVVNTTMALKDININLQSWRKSLNDSKNHTVIDLIEEGLY 359

Query: 309 PLHFFIKPDKL 319
           P+  F+     
Sbjct: 360 PMSDFVLERNF 370


>UniRef50_Q8I497 Delta2 protein n=1 Tax=Cupiennius salei RepID=Q8I497_CUPSA
          Length = 438

 Score = 47.2 bits (110), Expect = 0.002,   Method: Composition-based stats.
 Identities = 53/264 (20%), Positives = 78/264 (29%), Gaps = 52/264 (19%)

Query: 323 PGPLVKKLSKTVETAVRHYYTFNTH-PGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGV 381
               +     T++   R Y   N + P C N+  P  +            K  ++T    
Sbjct: 168 TQDELSTNQSTLKLMYRVYCATNYYGPNCGNLCRPRDD------------KFGHYT---- 211

Query: 382 YQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECK-KKCTLKI 440
              C E  G  LC+             C         L   H       ECK +   L  
Sbjct: 212 ---CKED-GQKLCKPGWS------GSYC----DKALCLPGCHGTCDLPDECKCRPGWLGK 257

Query: 441 FCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIP 500
           FC T C              W     Q   + G  +GG+F D  +N  TN + C  G   
Sbjct: 258 FCDT-CTRYPGCIHGTCNQPW-----QCNCDEG--WGGLFCDHDLNYCTNHKPCQNGGTC 309

Query: 501 LNLFESLKVCVSLDYELGFKFSV---PFGGFFSCIMGNPLVNSDTAKDVRAPSLK-KCPG 556
            N  +    C   +  +G   ++   P      C   NP  N+   ++         C  
Sbjct: 310 TNTGQGSYTCNCTEEFMGVNCNILKNP------CQK-NPCRNNGICENSSQGQYTCTCAP 362

Query: 557 GF-SQHLAVISDGCQVSYCVKAGI 579
           GF   H    +  C  + C   G 
Sbjct: 363 GFYGPHCETTASICTKNPCENGGS 386


>UniRef50_C3ZVU2 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZVU2_BRAFL
          Length = 278

 Score = 47.2 bits (110), Expect = 0.002,   Method: Composition-based stats.
 Identities = 18/90 (20%), Positives = 31/90 (34%), Gaps = 6/90 (6%)

Query: 173 KALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNS 232
            ++ +    LE      +    E  IL YGTH  TS   G  L     +  +     + S
Sbjct: 161 SSVEEYRHYLEDKSAMTSQT--ESFILRYGTHYTTSAKFGGQL----KIIKTKEASEEAS 214

Query: 233 QNTVTASAGIAFLNIVNFKVETDYISQTSL 262
           Q     +A   F  + +        +++S 
Sbjct: 215 QENFAQAAQSDFKKVFSTYSAQQTQTKSSS 244


>UniRef50_D1JPJ4 Putative uncharacterized protein n=2 Tax=Bacteroides
           RepID=D1JPJ4_9BACE
          Length = 506

 Score = 47.2 bits (110), Expect = 0.003,   Method: Composition-based stats.
 Identities = 43/242 (17%), Positives = 72/242 (29%), Gaps = 49/242 (20%)

Query: 112 SLSINTELALFSRVNGKFSTEFQRM---KTLQVKDQAVTTRVQVRNRIYTVKTTP-TSEL 167
           S     +L        +FS E+      K      +    R   R  + +         L
Sbjct: 151 SAKGKLKLGFLPWGGIQFSAEYDSNFETKDEYSFYKMDIIRNVRRLYLSSSSIERLKYFL 210

Query: 168 SLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLL 227
           +  F  AL                     +I +YGTHV+     G  L       +S + 
Sbjct: 211 TDEFRYALKHASGT--------------EIINDYGTHVLVDFVLGGKLSVV----TSAID 252

Query: 228 DNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFG-------- 279
            + N       S  I       FK+ +   S +    +YL N + + +Q+ G        
Sbjct: 253 HSDNKDELFKFSTKI-------FKIISASASSSISKSNYLKNTSLTILQAGGSEIQAVKR 305

Query: 280 -----GVPFYPGITLETWQKGITNH---LVAID-RAGLPLHFFIKPDKLPGLPGPLVKKL 330
                G         + W K I      LVA D +  + +         P +   ++ +L
Sbjct: 306 YIEEDGTINSDIFNYKEWIKSINKETSVLVASDTKKMIGIWELTDD---PKIKTKILAEL 362

Query: 331 SK 332
            K
Sbjct: 363 EK 364


>UniRef50_C6QX82 Putative lipoprotein n=2 Tax=Bacteria RepID=C6QX82_9ACTO
          Length = 586

 Score = 46.8 bits (109), Expect = 0.003,   Method: Composition-based stats.
 Identities = 38/292 (13%), Positives = 76/292 (26%), Gaps = 54/292 (18%)

Query: 91  ESNLEMNSEVLESWMNYQSTTSLSINTEL---ALFSRVNGKFSTEFQRMKTLQVKDQAVT 147
            +    NS        Y +  +  I+ ++         +  FS+ F   +          
Sbjct: 122 NTFASDNSFRSSMAKKYSNVFTAGIDFKIFKIGYERTFSSAFSSTFDFKERHV----YAE 177

Query: 148 TRVQVRNRIYTVKTTPTSE-------LSLGFTKALMDICDQLEKNQTKMATYLAELLILN 200
             V  +   YT++ +   +       LS  F   L +   Q     T             
Sbjct: 178 LNVLCQEARYTLERSKDLDNIIQNRYLSDAFRSNLYNTPFQKLFPSTG-----------R 226

Query: 201 YGTHVITSVDAGAALVQEDH----VRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDY 256
           YG+ V+T    G              ++        +N + AS  I      +       
Sbjct: 227 YGSLVVTQYILGGKANFLYQGMSKEETNETKLESEIRNKIDASCTIT-KGSFSITPSVGN 285

Query: 257 ISQTSLTKDYLSNRTNSRVQ----SFGG--------VPFYPGI--TLETWQKGITNH--- 299
            +  S +    S      ++    + GG           +  +      W   + +    
Sbjct: 286 NNGNSNSSSSSSTDFFESLRVVYETIGGAFAMGFSAPMKFDNLKVDFAPWVNSLNDKSTH 345

Query: 300 -LVAIDRAGL-PLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPG 349
            L+ I R GL P+  F++ +                 ++    Y        
Sbjct: 346 VLIDIPRGGLTPISEFVQEENFSKRIVYE-----AYNKSFSEPYMEIRLGRN 392


>UniRef50_UPI000186DD19 Neurogenic locus protein delta precursor, putative n=2 Tax=Neoptera
           RepID=UPI000186DD19
          Length = 684

 Score = 46.0 bits (107), Expect = 0.005,   Method: Composition-based stats.
 Identities = 41/190 (21%), Positives = 60/190 (31%), Gaps = 28/190 (14%)

Query: 403 LTGDFSCPPGYSPVHLL--------SQTHEEGYSRLECK-KKCTLKIFCKTVCEDVFRVA 453
           L+G   C  G+   +          S+ H       +C         FC   CE      
Sbjct: 103 LSGARVCLSGWKGDYCDQPKCLPGCSEEHGHCEQPNQCLCHNGWQGKFCNE-CERYPGCL 161

Query: 454 KAEFRAYW---CVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVC 510
               +  W   C             +GG+F ++ +N  TN + C  G    N  E    C
Sbjct: 162 HGTCQKQWDCNCEEG----------WGGLFCNQDLNYCTNHKPCKNGGTCFNTGEGSYTC 211

Query: 511 VSLDYELGFKFSVPFGGFFSCIM-GNPLVNSDTAKDVRAPSLKKCPGGF-SQHLAVISDG 568
                E GF          SC    NP  N     D+       CP GF   H  +++  
Sbjct: 212 SC---EPGFTGRDCEHMLDSCTTHQNPCQNGGKCNDLGKGYTCDCPKGFHGNHCEIVTVT 268

Query: 569 CQVSYCVKAG 578
           C+ + C+  G
Sbjct: 269 CKDTTCLNGG 278


>UniRef50_C4JS74 Predicted protein n=1 Tax=Uncinocarpus reesii 1704
           RepID=C4JS74_UNCRE
          Length = 421

 Score = 46.0 bits (107), Expect = 0.005,   Method: Composition-based stats.
 Identities = 29/249 (11%), Positives = 59/249 (23%), Gaps = 46/249 (18%)

Query: 78  YIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMK 137
           + +PD V        N E +     +     S      +      + V+   S  +   K
Sbjct: 58  WTVPDNVNVAA-DAGNSETSQTSYTNGSVAASNLEADASLSGQYLA-VSAGASANYSISK 115

Query: 138 TLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDI-CDQLEKNQTKMA-----T 191
           T     Q                          F + L+++  +   +NQ + A      
Sbjct: 116 TFHSSYQYFMFN---------------------FRQVLLEVGLENFAENQYQRACMAHVV 154

Query: 192 YLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFK 251
              +     +G+HV+T    G+   Q                     +A   F   +   
Sbjct: 155 KTYKTFFGTFGSHVVTGTTYGSRF-QLAQFN--------------GLTASGNFDASIKTT 199

Query: 252 VETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGI--TLETWQKGITNHLVAIDRAGLP 309
            +      +            S        P    +  +  +W K        +    + 
Sbjct: 200 DQYKTFETSVQKNCSCQGGDTSIGTKIASDPTTTDVYTSYASWTKSSQTTPGVMTMQTMS 259

Query: 310 LHFFIKPDK 318
           L   +    
Sbjct: 260 LWELMTAAM 268


>UniRef50_Q4SU28 Chromosome undetermined SCAF14025, whole genome shotgun sequence.
           (Fragment) n=8 Tax=Eumetazoa RepID=Q4SU28_TETNG
          Length = 1957

 Score = 45.6 bits (106), Expect = 0.006,   Method: Composition-based stats.
 Identities = 37/189 (19%), Positives = 51/189 (26%), Gaps = 27/189 (14%)

Query: 385 CTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKK--CTLKIFC 442
           C       +  +       +   SCP GY+  H  S  +   Y    C  +  CTL  F 
Sbjct: 22  CLNGGNCSVSTSAGVPVPGSATCSCPLGYTGQHCQSPQNSTCYPNNPCANRGVCTLLPFN 81

Query: 443 KTVCE------DVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPA 496
           K  CE            + +  +  C   G     SG  F                SCP 
Sbjct: 82  KYKCECARGWTGTGCEYEDKCLSSPCANGGTCSSVSGGSF--------------TCSCPP 127

Query: 497 GYIPLNLFESLKVCV---SLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKK 553
           GY           C    S+    G   + P  G + C+                 S   
Sbjct: 128 GYAGARCLNDTNECAATPSICQNEGGCINTP--GSYKCVCTPGFTGKHCESSYIPCSPSP 185

Query: 554 CPGGFSQHL 562
           C  G + H 
Sbjct: 186 CLNGGTCHQ 194


>UniRef50_D2VK21 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VK21_NAEGR
          Length = 452

 Score = 45.6 bits (106), Expect = 0.006,   Method: Composition-based stats.
 Identities = 36/222 (16%), Positives = 63/222 (28%), Gaps = 51/222 (22%)

Query: 103 SWMNYQSTTSLSINTELALFSRVNGKF---STEFQRMKTLQVKDQAVTTRVQVRNRIYTV 159
           S   Y    S +   +L       G+F   +++ Q +      +                
Sbjct: 88  SSKVYNGLYSHNEGVDLIFSKYFQGEFTVYNSQKQFVSHHVESEGTSIV----------- 136

Query: 160 KTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQED 219
                     GF K +  +  Q + +       L  L++  +G  V+TSVD G  +    
Sbjct: 137 ---------SGFEKIIEFLPGQYDAD-------LYNLVLSYFGDSVLTSVDYGGVVDLTS 180

Query: 220 HVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFG 279
            VRS F             S             +    +  S+   Y      S++   G
Sbjct: 181 SVRSCFSDGRIQQFVQSELS-------------DIVGQAAESMPDSYARYHKVSQMDIVG 227

Query: 280 GVPFYPGITLETWQKGITN---HLVAIDRAGLPLHFFIKPDK 318
           G P    I     ++ I     + V I    +P+        
Sbjct: 228 GNPEISDI-----RQRIPTFSANPVPIFFTTIPIWQAFPAGS 264


>UniRef50_A0ZVQ7 Delta n=2 Tax=Entelegynae RepID=A0ZVQ7_PARTP
          Length = 785

 Score = 45.6 bits (106), Expect = 0.007,   Method: Composition-based stats.
 Identities = 47/239 (19%), Positives = 75/239 (31%), Gaps = 44/239 (18%)

Query: 370 DAKVTNFTFGGVYQECTELSGDVLCQNLEQK-NLLTGDFSC-PPG-----------YSPV 416
               T F++  +   C +      C+ L +  N   G ++C P G           Y  V
Sbjct: 167 KTNHTAFSY-AIRVRCLDNYYGDNCEKLCRPRNDKFGHYTCSPTGDKVCYRGWTGEYCTV 225

Query: 417 HLLS----QTHEEGYSRLECK-KKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDN 471
            +      + H       EC+ +       C   C              W     Q   +
Sbjct: 226 AVCLPGCHEEHGYCEEPNECRCRLGWQGSHC-NQCIRYPGCLHGTCNQPW-----QCNCD 279

Query: 472 SGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSC 531
            G  +GG+F ++ +N  TN + C  G    N  +    C  +D   G           +C
Sbjct: 280 EG--WGGLFCNQDLNYCTNHKPCKHGGTCTNTGQGSYTCTCIDGYSGK----------NC 327

Query: 532 I------MGNPLVNSDTAKDVRAPSLKKCPGG-FSQHLAVISDGCQVSYCVKAGIFTGG 583
                  +  P +N  T K +      +CP G F QH    +  C  + C   G    G
Sbjct: 328 EKQADDCVNQPCLNGATCKSLGKNYTCECPLGFFGQHCETAASTCTENPCQNGGTCVDG 386


>UniRef50_Q7PR44 AGAP003027-PA (Fragment) n=1 Tax=Anopheles gambiae
           RepID=Q7PR44_ANOGA
          Length = 474

 Score = 45.2 bits (105), Expect = 0.010,   Method: Composition-based stats.
 Identities = 26/134 (19%), Positives = 35/134 (26%), Gaps = 19/134 (14%)

Query: 350 CTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQN------------L 397
           C      N +         C         G  +  C   + + LC               
Sbjct: 315 CEGACGVNADCNLRGLTPVCSCPRDMT--GDPFISCRPFTKEDLCSPNPCGTNAVCTPGY 372

Query: 398 EQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLEC--KKKCTLKIF---CKTVCEDVFRV 452
           ++ N      +CPPGY+   L S    E  S  EC   K C        C   C    + 
Sbjct: 373 DRSNQERPVCTCPPGYTGNALSSCVRGECQSDAECADHKACIAYQCVDPCSGQCGVGAQC 432

Query: 453 AKAEFRAYWCVAAG 466
                 A     AG
Sbjct: 433 QAKRHLAVCTCPAG 446


>UniRef50_Q5RGG6 Novel protein similar to vertebrate delta-like 4 (Drosophila)
           (DLL4) (Fragment) n=1 Tax=Danio rerio RepID=Q5RGG6_DANRE
          Length = 645

 Score = 44.9 bits (104), Expect = 0.012,   Method: Composition-based stats.
 Identities = 49/261 (18%), Positives = 67/261 (25%), Gaps = 66/261 (25%)

Query: 350 CTNVDS-PNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFS 408
           CT   + P            C+ K     +GG++  C +  G   C              
Sbjct: 225 CTECKTYPACKHGTCHLPGQCNCKE---GWGGLF--CDQGQGSYTCI------------- 266

Query: 409 CPPGYSPVHLLSQTHEEGYSRLE------CKKKCTLKIFCKTVCEDVFRVAKAEFRAYWC 462
           C PGY+ V+   Q  E   S  +         K                 +        C
Sbjct: 267 CRPGYTGVNCELQVRECDSSPCKNGGLCTDHDKSYTCTCLPDFEGTHCEHSLLTCADSPC 326

Query: 463 VAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVS----LDYELG 518
              G+  +               N  + A  CP GY  LN    +  C S     D   G
Sbjct: 327 FHKGRCHEK-------------DNGRSYACECPLGYTGLNCERRMDKCTSMLCAND---G 370

Query: 519 FKFSVPFGGFFSCIMG---------------NPLVNSDTAKDVRAPSLKKCPGGFSQHLA 563
               +      SC  G               NP  N  T  D     +  CP G+     
Sbjct: 371 LCLILGGKRICSCRAGFTGQRCEININDCANNPCANGGTCYDRINEYVCSCPPGYK---- 426

Query: 564 VISDGCQVSYCVKAGIFTGGS 584
                C    C+      GGS
Sbjct: 427 --GRNCDRPSCLSTPCLNGGS 445


>UniRef50_B7PT11 LIN-12 protein, putative n=2 Tax=Coelomata RepID=B7PT11_IXOSC
          Length = 2298

 Score = 44.9 bits (104), Expect = 0.013,   Method: Composition-based stats.
 Identities = 43/221 (19%), Positives = 57/221 (25%), Gaps = 40/221 (18%)

Query: 363 NMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQT 422
           N    +C A  T    G + Q          C++      L   + C            T
Sbjct: 501 NSFSCNCHAGYT----GLLCQTQINECLSSPCRHGGTCEDLVNGYQC-------RCRPGT 549

Query: 423 HEEG--YSRLEC-KKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGV 479
                 Y+  EC    C     C    +       A F    C        ++    GGV
Sbjct: 550 SGVDCEYNVNECFSNPCRHGAKCIDGIDSYTCDCLAGFTGIHCETNINECASNPCSNGGV 609

Query: 480 FTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVN 539
            TD           CP GY        +  C S                      NP  N
Sbjct: 610 CTDLVNG---FKCDCPRGYFDARCLSDVNECAS----------------------NPCQN 644

Query: 540 SDTAKDVRAPSLKKCPGGFSQHLAVIS-DGCQVSYCVKAGI 579
             T +D     +  CP G+  H      D CQ + C   G 
Sbjct: 645 GGTCEDEVNRFVCHCPPGYGGHRCEQDIDECQSNPCQHGGS 685


>UniRef50_C3YG94 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
            RepID=C3YG94_BRAFL
          Length = 2219

 Score = 44.5 bits (103), Expect = 0.014,   Method: Composition-based stats.
 Identities = 40/263 (15%), Positives = 65/263 (24%), Gaps = 40/263 (15%)

Query: 346  THPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNL-LT 404
            T   C +  S       + D         +F+  G+ Q C     +         N    
Sbjct: 1069 TCLACPDSKSTVGMNSTSQDQCISHCLAGHFSPTGL-QPCEPCPLNTYN-----PNPGRR 1122

Query: 405  GDFSCPPGYSPVHLLSQTHEEGYSRLECKK-KCTLKIFCKTVCEDVFRVAKAEFRAYWCV 463
            G   CP       L + +  + ++   C    C     C+ +           +    C 
Sbjct: 1123 GCVDCPGTQETFFLGATSPNDCFANDNCHSNPCQNGATCEDLVGGYLCHCAPGYNGTDCE 1182

Query: 464  AAGQVPDNSGLLFGGVFTDKTINPMTNA------QSCPAGYIPLNLFESLKVCVSLDYEL 517
                             T    N            +C +GY        +  C S   + 
Sbjct: 1183 QDVDDCA---------STPCNNNGTCQDLINGFNCTCVSGYTGDTCQMEVNECASSPCQH 1233

Query: 518  GF----------KFSVPFGGFFSCIM------GNPLVNSDTAKDVRAPSLKKCPGGFS-Q 560
            G            + +P     SC         +P ++  +  D        CP GF+  
Sbjct: 1234 GGTCIDLFNTYQCYCLPGYAGHSCQQEIDECDSSPCLSGASCVDEVDGYRCDCPPGFTGD 1293

Query: 561  HLAVISDGCQVSYCVKAGIFTGG 583
            H     D CQ   C   G     
Sbjct: 1294 HCDREIDECQSQPCQNGGTCNDQ 1316


>UniRef50_Q76B58 Protein FAM5C n=21 Tax=Euteleostomi RepID=FAM5C_HUMAN
          Length = 766

 Score = 44.5 bits (103), Expect = 0.016,   Method: Composition-based stats.
 Identities = 23/136 (16%), Positives = 43/136 (31%), Gaps = 12/136 (8%)

Query: 128 KFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQT 187
            FST ++  +            V+ RN + +        L+  F + +  +  +    Q 
Sbjct: 70  GFSTRYKIYREFGRWKVN-NLAVERRNFLGS-----PLPLAPEFFRNIRLLGRRPTLQQ- 122

Query: 188 KMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNI 247
                + E LI  YGTH + S   G        V    L       ++ T S+ +    +
Sbjct: 123 -----ITENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSKRAEGSDSTTNSSSVTLETL 177

Query: 248 VNFKVETDYISQTSLT 263
                       ++L 
Sbjct: 178 HQLAASYFIDRDSTLR 193


>UniRef50_B5B3T0 Delta protein n=2 Tax=Deuterostomia RepID=B5B3T0_SACKO
          Length = 895

 Score = 44.1 bits (102), Expect = 0.017,   Method: Composition-based stats.
 Identities = 49/263 (18%), Positives = 79/263 (30%), Gaps = 52/263 (19%)

Query: 347 HPGCTNVD-SPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTG 405
           H  C N     N N   N+   +C    T        +   +   D  CQN    N L  
Sbjct: 311 HKPCKNGGTCSNGNSGGNLYTCTCPPGFTGTD----CEVEIDDCIDNPCQNGGVCNDLIN 366

Query: 406 DFSC--PPGYSPVHLLSQTHEEGYSRLECK---KKCTLKIFCKTVCEDVFRVAKAEFRAY 460
           +++C  PP ++ V    +   E  S   C+               C D +   + E    
Sbjct: 367 NYACQCPPAFTGV--HCEILIESCSEHPCQNGATCVENGADFICTCSDGYTGHRCEQEID 424

Query: 461 WCVAAGQ-------VPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSL 513
           +C +          +   SG +                  C  G+        L+ C   
Sbjct: 425 YCSSEPCQNGATCIIDQQSGFI----------------CQCAPGFEGTACENQLEFCDPD 468

Query: 514 DYELG-FKFSVPFGGFFSCIMGN---------------PLVNSDTAKDVRAPSLKKCPGG 557
             + G    + P+  +  C+ G                P  N  T  D+      +CP G
Sbjct: 469 PCQNGATCHNGPYNFYCDCVPGYIGDLCENDFDECLLLPCSNGGTCSDLVNNFHCECPAG 528

Query: 558 FSQHLAVIS-DGCQVSYCVKAGI 579
           F+     ++ D CQ + C   GI
Sbjct: 529 FTGKDCSVAVDLCQSNPCHNGGI 551


>UniRef50_B3RTL5 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
            RepID=B3RTL5_TRIAD
          Length = 7710

 Score = 43.7 bits (101), Expect = 0.025,   Method: Composition-based stats.
 Identities = 40/238 (16%), Positives = 69/238 (28%), Gaps = 36/238 (15%)

Query: 355  SPNFNFQANMDDDSCD-AKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGY 413
             P+ ++QA     +C       +    V     +     L   +    +    + CP G 
Sbjct: 4103 CPSGSYQAFAGQGNCTVCPDGYYCDATVAVLEKQSGPSSLTHGVVTPAICPVGYYCPEGT 4162

Query: 414  SPVHLLS------QTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQ 467
               +  +             ++ EC   CT   +C              +  Y+C     
Sbjct: 4163 KSSYENACPAGTYSNKTSIKTKHEC-LSCTPGYYCAGTANT--EPDGKCYAGYYCAMNAT 4219

Query: 468  VPDNSGLLFGGVFTDKTINPMTNA--QSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPF 525
             P  +  L G +    +  P+ ++    CP+G    +L  + +V    D   G     P 
Sbjct: 4220 SPSPTEGLTGDICPQGSYCPLGSSWPTPCPSGTYGASLGLT-QVTQCTDCPPGMACQTP- 4277

Query: 526  GGFF----SCIMG----------NPLVN-------SDTAKDVRAPSLKKCPGGFSQHL 562
             G      SC  G          NPL               + + +   CP G  Q L
Sbjct: 4278 -GLIQPSSSCQSGYYCILKAILPNPLGESYGSICPPGAYCPINSSAPTLCPPGTYQPL 4334


>UniRef50_Q61483 Delta-like protein 1 n=31 Tax=Euteleostomi RepID=DLL1_MOUSE
          Length = 722

 Score = 43.3 bits (100), Expect = 0.033,   Method: Composition-based stats.
 Identities = 47/236 (19%), Positives = 73/236 (30%), Gaps = 44/236 (18%)

Query: 347 HPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVY--QECTELSGDVLCQNLEQ-KNLL 403
           +PGC                  C+ +     +GG++  Q+    +    C+N     N  
Sbjct: 259 YPGCL--------HGTCQQPWQCNCQE---GWGGLFCNQDLNYCTHHKPCRNGATCTNTG 307

Query: 404 TGDFSCP--PGYSPVHLLSQTHEEGYSRLECKKKCT-LKIFCKTVCEDVFRVAKAEFRAY 460
            G ++C   PGY+  +   +  E   S  +    CT L+      C   F     E  A 
Sbjct: 308 QGSYTCSCRPGYTGANCELEVDECAPSPCKNGASCTDLEDSFSCTCPPGFYGKVCELSAM 367

Query: 461 WCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFK 520
            C              GG  +D      T    CP G+   N  + + +C S     G K
Sbjct: 368 TCADGPCFN-------GGRCSDNPDGGYT--CHCPLGFSGFNCEKKMDLCGSSPCSNGAK 418

Query: 521 FSVPFGGFFSCI-----------------MGNPLVNSDTAKDVRAPSLKKCPGGFS 559
             V  G  + C                    +P  N  T +D        CP G++
Sbjct: 419 -CVDLGNSYLCRCQAGFSGRYCEDNVDDCASSPCANGGTCRDSVNDFSCTCPPGYT 473


>UniRef50_Q2TXD5 Predicted protein n=2 Tax=Aspergillus RepID=Q2TXD5_ASPOR
          Length = 557

 Score = 43.3 bits (100), Expect = 0.037,   Method: Composition-based stats.
 Identities = 34/234 (14%), Positives = 66/234 (28%), Gaps = 21/234 (8%)

Query: 68  TNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQ-STTSLSINTELALFSR-- 124
           ++ +   + Q+ IP  V          E  S V  +      S+     + E   F    
Sbjct: 62  SDSEVKIEQQFHIPRFVVADDSYVDTFETKSSVATAMARSSFSSIEAEASIEGGAFGFSA 121

Query: 125 -VNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTP-TSELSLGFTKALMDICDQL 182
            V+  FS+      + Q   ++ T  +        +     +  LS   ++ L+ + D  
Sbjct: 122 AVSAGFSSSESNALSKQSTAESSTMNITYNFPRVVLHLDEYSLALSDECSQDLIRVKDVN 181

Query: 183 EKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGI 242
                             YG    T V+ G  L   +   +        +   +  SA  
Sbjct: 182 S----------LIAFHHKYGHFFATRVELGGRLFSSEKFSTLGTSSESEATKQMKISASA 231

Query: 243 AFLNIVNFKVETDYISQTSLT---KDYLSNRTNSRV-QSFGGVPFYPGITLETW 292
           +  +         Y  +   +    D   +  +S   Q+ GG           W
Sbjct: 232 S-FSSKFVSGSASYSQENGQSGQDSDARRSMQSSISWQAQGGDTLLCN-NPPAW 283


>UniRef50_B8NXE5 Putative uncharacterized protein n=1 Tax=Aspergillus flavus
           NRRL3357 RepID=B8NXE5_ASPFN
          Length = 736

 Score = 42.2 bits (97), Expect = 0.076,   Method: Composition-based stats.
 Identities = 28/246 (11%), Positives = 67/246 (27%), Gaps = 19/246 (7%)

Query: 78  YIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMK 137
           + I D+ Y    +E+     +    S   + ++ ++         +  +  +        
Sbjct: 265 FRIEDDSYVEQFEETKSVSRAVAASSMSQFDASLAIEGGA-FGFSASASASYGDTSSSSD 323

Query: 138 TLQVKDQAVTTRVQVRNRIYTVKT-TPTSELSLGFTKALMDICDQLEKNQTKMATYLAEL 196
           +    ++     +       T+     + +LS      L  +    +           E 
Sbjct: 324 SSSSNEENKVMNITYNFPRVTIDFDHQSLDLSNQCKADLKAVSTAADI----------ES 373

Query: 197 LILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLN-IVNFKVETD 255
               YG      V  G  L   +   +    +      +  A+A ++F +  V       
Sbjct: 374 FKNKYGRLFAMRVQLGGRLHAAEESTARTSAEKAEHAKSQRAAAALSFKSPYVQASANVS 433

Query: 256 YISQTSLTKDYLSNRTNSRV--QSFGGVPFYPGITLETWQ---KGITNHLVAIDRAGLPL 310
             S    +    ++ +N  +  ++ GG           W        N  V    + L +
Sbjct: 434 KSSAEDSSSATQNSSSNKSMCWEAKGGDTLLCN-DPPAWAYTVGSFYNWRVVKQSSVLAI 492

Query: 311 HFFIKP 316
              I  
Sbjct: 493 EDVISS 498


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.305    0.117    0.308 

Lambda     K      H
   0.267   0.0363    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,573,536,556
Number of Sequences: 3077464
Number of extensions: 134271126
Number of successful extensions: 387756
Number of sequences better than 1.0e-01: 246
Number of HSP's better than  0.1 without gapping: 108
Number of HSP's successfully gapped in prelim test: 221
Number of HSP's that attempted gapping in prelim test: 386838
Number of HSP's gapped (non-prelim): 581
length of query: 713
length of database: 1,040,396,356
effective HSP length: 136
effective length of query: 577
effective length of database: 621,861,252
effective search space: 358813942404
effective search space used: 358813942404
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 96 (41.8 bits)
