Job Description A2A4P0 Confidence 99.95% Date Wed Jul 10 14:06:11 BST 2013 Rank 21 Aligned Residues 529 % Identity 14% Template c4bgdA_ PDB info PDB header:transcription Chain: A: PDB Molecule:pre-mrna-splicing helicase brr2; PDBTitle: crystal structure of brr2 in complex with the jab1/mpn domain of prp8 Resolution 3.10 Å

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		593	.	.	.	.	.	.	600	.	.		.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.
Predicted Secondary structure												.
Query SS confidence												.
Query Sequence		K	L	K	E	Q	L	V	Q	A	V	.	H	D	N	Q	I	L	I	V	I	G	E	T	G	S	G	K	T	T	Q	I	T	Q	Y	L	A	E	A	G	Y	T	S	R	G	K	I	G	C	T	Q	P	R	R	V	A	A	M	S	V	A
Query Conservation												.
Alig confidence												.
Template Conservation
Template Sequence		K	I	Q	S	Q	V	F	E	S	L	Y	N	S	N	D	S	V	F	V	G	S	G	K	G	T	G	K	T	A	M	A	E	L	A	L	L	N	H	W	R	Q	N	K	G	R	A	V	Y	I	N	P	S	G	E	K	I	D	F	L	L
Template Known Secondary structure													T			S								T	T	S															T	T	T									S
Template Predicted Secondary structure
Template SS confidence
		1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400	.	.	.	.	.	.	.	.	.
		652	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.					.	.	680	.	.	.	.	.	.	.	.				.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.
Predicted Secondary structure																												.	.	.	.												.	.	.
Query SS confidence																												.	.	.	.												.	.	.
Query Sequence		K	R	V	S	E	E	F	G	C	C	L	G	Q	E	V	G	Y	T	I	R	F	E	D	C	T	S	.	.	.	.	P	E	T	V	I	K	Y	M	T	D	G	.	.	.	M	L	L	R	E	C	L	I	D	P	D	L	T	Q	Y	A
Query Conservation																												.	.	.	.												.	.	.
Alig confidence																												.	.	.	.												.	.	.
Template Conservation
Template Sequence		S	D	W	N	K	R	F	S	H	L	A	G	G	K	I	I	N	K	L	G	N	D	P	S	L	N	L	K	L	L	A	K	S	H	V	L	L	A	T	P	V	Q	F	E	L	L	S	R	R	W	R	Q	R	K	N	I	Q	S	L	E
Template Known Secondary structure									T	T	T	T	T								T	T													S														T	T	T	T	T						T
Template Predicted Secondary structure
Template SS confidence
		1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.
		705	.	.	.	.	710	.	.						.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.		.	.	.	.	.	.	.	.	740	.	.	.	.		.	.	.	.	.	750	.	.	.	.	.	.	.
Predicted Secondary structure										.	.	.	.	.																				.														.
Query SS confidence										.	.	.	.	.																				.														.
Query Sequence		I	I	M	L	D	E	A	H	.	.	.	.	.	E	R	T	I	H	T	D	V	L	F	G	L	L	K	K	T	V	Q	K	.	R	Q	D	M	K	L	I	V	T	S	A	T	L	.	D	A	V	K	F	S	Q	Y	F	Y	E	A	P
Query Conservation										.	.	.	.	.																				.														.
Alig confidence										.	.	.	.	.																				.														.
Template Conservation
Template Sequence		L	M	I	Y	D	D	A	H	E	I	S	Q	G	V	Y	G	A	V	Y	E	T	L	I	S	R	M	I	F	I	A	T	Q	L	E	K	K	I	R	F	V	C	L	S	N	C	L	A	N	A	R	D	F	G	E	W	A	G	M	T	K
Template Known Secondary structure						T	T	G	G	G	G	G	S	S																					T										S			S									T	T			G
Template Predicted Secondary structure
Template SS confidence
		1470	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.
						758	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780								.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.																								.	.	.	.	.	.	.
Query SS confidence		.	.	.	.																								.	.	.	.	.	.	.
Query Sequence		.	.	.	.	I	F	T	I	P	G	R	T	Y	P	V	E	I	L	Y	T	K	E	P	E	T	D	Y	.	.	.	.	.	.	.	L	D	A	S	L	I	T	V	M	Q	I	H	L	T	E	P	P	G	D	I	L	V	F	L	T	G
Query Conservation		.	.	.	.																								.	.	.	.	.	.	.
Alig confidence		.	.	.	.																								.	.	.	.	.	.	.														.	.
Template Conservation																																																	.	.
Template Sequence		S	N	I	Y	N	F	S	P	S	E	R	I	E	P	L	E	I	N	I	Q	S	F	K	D	V	E	H	I	S	F	N	F	S	M	L	Q	M	A	F	E	A	S	A	A	A	A	G	.	.	N	R	N	S	S	S	V	F	L	P	S
Template Known Secondary structure		G	G						G	G	G		S	S										T	T		T	T	S	S																			.	.	T	T								S	S
Template Predicted Secondary structure																																																	.	.
Template SS confidence
		1530	.	.	.	.	.	.	.	.	.	1540	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.	.	.	.	.	1560	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.			.	.	.	1580	.	.	.	.	.	.	.
		807	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.																								.	.	.	.	.	.	.	840	.	.	.
Predicted Secondary structure																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		Q	E	E	I	D	T	A	C	E	I	L	Y	E	R	M	K	S	L	G	P	D	V	P	E	L	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	L	P	V	Y	S	A	L	P	S	E
Query Conservation																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		R	K	D	C	M	E	V	A	S	A	F	M	K	F	S	K	A	I	E	W	D	M	L	N	V	E	E	E	Q	I	V	P	Y	I	E	K	L	T	D	G	H	L	R	A	P	L	K	H	G	V	G	I	L	Y	K	G	M	A	S	N
Template Known Secondary structure																		T	S	S					S	S		T	T	T						T	T		S	S	G	G	G					T	T	T						T	T
Template Predicted Secondary structure
Template SS confidence
		1588	.	1590	.	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610	.	.	.	.	.	.	.	.	.	1620	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.	.	.	.	1640	.	.	.	.	.	.	.
		844	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	Q	T	R	I	F	D	P	A	P	P	G	S	R	K	V	V	I	A	T	N	I	A	E	T	S	L	T	I	D	G	I	Y	Y	V	V	D	P	G	F	V	K	Q	K	V	Y	N	S	K	T	G	I	D	Q	L	V	V	T	P	I
Query Conservation
Alig confidence																									.													.	.	.	.												.	.	.	.
Template Conservation																									.													.	.	.	.												.	.	.	.
Template Sequence		D	E	R	I	V	K	R	L	Y	E	Y	G	A	V	S	V	L	L	I	S	K	D	C	.	S	A	F	A	C	K	T	D	E	V	I	I	.	.	.	.	L	G	T	N	L	Y	D	G	A	E	H	.	.	.	.	K	Y	M	P	Y
Template Known Secondary structure													T	S	S							T	G	G	.	G	G	S				B	S					.	.	.	.								T	T	T	T	.	.	.	.
Template Predicted Secondary structure																									.													.	.	.	.												.	.	.	.
Template SS confidence
		1648	.	1650	.	.	.	.	.	.	.	.	.	1660	.	.	.	.	.	.	.	.	.	1670		.	.	.	.	.	.	.	.	.	1680	.	.					.	.	.	.	.	.	.	1690	.	.	.					.	.	.	.	.
		904	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920			.	.	.	.	.	.	.	.			.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.			.	.	.	.	.	950	.	.	.	.	.	.	.
Predicted Secondary structure																			.	.									.	.																	.	.
Query SS confidence																			.	.									.	.																	.	.
Query Sequence		S	Q	A	Q	A	K	Q	R	A	G	R	A	G	R	T	G	P	.	.	G	K	C	Y	R	L	Y	T	.	.	E	R	A	Y	R	D	E	M	L	T	T	N	V	P	E	I	.	.	Q	R	T	N	L	A	S	T	V	L	S	L	K
Query Conservation																			.	.									.	.																	.	.
Alig confidence																			.	.									.	.																	.	.
Template Conservation
Template Sequence		T	I	N	E	L	L	E	M	V	G	L	A	S	G	N	D	S	M	A	G	K	V	L	I	L	T	S	H	N	M	K	A	Y	Y	K	K	F	L	I	E	P	L	P	T	E	S	Y	L	Q	Y	I	I	H	D	T	L	N	N	E	I
Template Known Secondary structure											T	T	B			S	T	T																					T	T	S								G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		1699	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740	.	.	.	.	.	.	.	.	.	1750	.	.	.	.	.	.	.	.
		958	.	960	.																						.	.	.	.	.	.	.	.	970	.	.	.	.								.	.	.	.	.	980	.	.	.	.	.	.	.	.	.
Predicted Secondary structure						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.
Query SS confidence						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.
Query Sequence		A	M	G	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	D	L	L	S	F	D	F	M	D	A	P	P	.	.	.	.	.	.	.	M	E	T	L	I	T	A	M	E	Q	L	Y	T	L	G
Query Conservation						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.
Alig confidence						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	N	S	I	I	Q	S	K	Q	D	C	V	D	W	F	T	Y	S	Y	F	Y	R	R	I	H	V	N	P	S	Y	Y	G	V	R	D	T	S	P	H	G	I	S	V	F	L	S	N	L	V	E	T	C	L	N	D	L	V	E	S	S
Template Known Secondary structure			T	T	S			S	S									T	S														T		S	S		S																						T	T
Template Predicted Secondary structure
Template SS confidence
		1759	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.	1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.
		990	.				.	.	.	.	.	.			.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.			.	1040	.	.
Predicted Secondary structure				.	.	.							.	.																																										.	.
Query SS confidence				.	.	.							.	.																																										.	.
Query Sequence		A	L	.	.	.	D	D	E	G	L	L	.	.	T	R	L	G	R	R	M	A	E	F	P	L	E	P	M	L	C	K	M	L	I	M	S	V	H	L	G	C	S	E	E	M	L	T	I	V	S	M	L	S	V	.	.	Q	N	V	F
Query Conservation				.	.	.							.	.																																										.	.
Alig confidence				.	.	.							.	.																																										.	.
Template Conservation
Template Sequence		F	I	E	I	D	D	T	T	E	I	I	S	T	L	S	N	G	L	I	A	S	H	Y	G	V	S	F	F	T	I	Q	S	F	V	S	S	L	S	N	T	S	T	L	K	N	M	L	Y	V	L	S	T	A	V	E	F	E	S	V	P
Template Known Secondary structure		S																																						T	T												T		G	G	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1819	1820	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.	1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.
		1043	.	.	.	.	.	.	1050	.	.	.	.	.	.	.							.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.		.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.
Predicted Secondary structure																	.	.	.	.	.	.																				.
Query SS confidence																	.	.	.	.	.	.																				.
Query Sequence		Y	R	P	K	D	K	Q	A	L	A	D	Q	K	K	A	.	.	.	.	.	.	K	F	H	Q	T	E	G	D	H	L	T	L	L	A	V	Y	N	S	W	.	K	N	N	K	F	S	N	P	W	C	Y	E	N	F	I	Q	A	R	S
Query Conservation																	.	.	.	.	.	.																				.
Alig confidence																	.	.	.	.	.	.																				.													.	.	.
Template Conservation																																																							.	.	.
Template Sequence		L	R	K	G	D	R	A	L	L	V	K	L	S	K	R	L	P	L	R	F	P	E	H	T	S	S	G	S	V	S	F	K	V	F	L	L	L	Q	A	Y	F	S	R	L	E	L	P	V	D	F	Q	N	D	.	.	.	L	K	D	I
Template Known Secondary structure				T	T												S	S					T	T	S		S	S	S														T	T											.	.	.
Template Predicted Secondary structure																																																							.	.	.
Template SS confidence
		1894	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.	.	.	.	.	.	.	.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.				.	.	.	1950
		1096	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	R	A	Q	D	I	R	K	Q	M	L	G	I	M	D	R	H	K	L	D	V	V	S	C	G	K	S	T	V	R	V	Q	K	A	I	C	S	G	F	F	R	N
Query Conservation
Alig confidence																								.			.	.
Template Conservation																								.			.	.
Template Sequence		L	E	K	V	V	P	L	I	N	V	V	V	D	I	L	S	A	N	G	Y	L	N	.	A	T	.	.	T	A	M	D	L	A	Q	M	L	I	Q	G	V	W	D	V
Template Known Secondary structure																			T	T	B	T	T	.			.	.												T	S		S	S
Template Predicted Secondary structure																								.			.	.
Template SS confidence
		1951	.	.	.	.	.	.	.	.	1960	.	.	.	.	.	.	.	.	.	1970	.	.		.	.			.	.	.	.	.	1980	.	.	.	.	.	.	.	.	.	1990