Job Description A2A4P0 Confidence 100.00% Date Wed Jul 10 14:06:11 BST 2013 Rank 7 Aligned Residues 361 % Identity 17% Template c2wv9A_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:flavivirin protease ns2b regulatory subunit, flavivirin PDBTitle: crystal structure of the ns3 protease-helicase from murray2 valley encephalitis virus Resolution 2.75 Å Model Dimensions (Å) X:70.971 Y:60.042 Z:43.673

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		600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	A	V	H	D	N	Q	I	L	I	V	I	G	E	T	G	S	G	K	T	T	Q	I	T	Q	Y	L	A	E	A	G	Y	T	S	R	G	K	I	G	C	T	Q	P	R	R	V	A	A	M	S	V	A	K	R	V	S	E	E	F	G
Query Conservation
Alig confidence																																																										.	.	.	.
Template Conservation																																																										.	.	.	.
Template Sequence		E	M	L	K	K	R	Q	L	T	V	L	D	L	H	P	G	A	G	K	T	R	R	I	L	P	Q	I	I	K	D	A	I	Q	K	R	L	R	T	A	V	L	A	P	T	R	V	V	A	A	E	M	A	E	A	L	R	.	.	.	.
Template Known Secondary structure		G	G	G	S	T	T									T	T	T	T	T	T	T	T												T	T								S	S											T	T	.	.	.	.
Template Predicted Secondary structure																																																										.	.	.	.
Template SS confidence
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
		660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.			.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.
Predicted Secondary structure																								.	.
Query SS confidence																								.	.
Query Sequence		C	C	L	G	Q	E	V	G	Y	T	I	R	F	E	D	C	T	S	P	E	T	V	.	.	I	K	Y	M	T	D	G	M	L	L	R	E	C	L	I	D	P	D	L	T	Q	Y	A	I	I	M	L	D	E	A	H	E	R	T	I	H
Query Conservation																								.	.
Alig confidence		.	.	.	.	.	.	.																.	.
Template Conservation		.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	G	L	P	V	R	Y	L	T	P	R	E	H	S	G	N	E	I	V	D	V	M	C	H	A	T	L	T	H	R	L	M	S	P	L	R	V	P	N	Y	N	L	F	V	M	D	E	A	H	F	T	D	P	A
Template Known Secondary structure		.	.	.	.	.	.	.	T	S												S																		S	S	S						S						S	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.
Template SS confidence
									238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
		718	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	D	V	L	F	G	L	L	K	K	T	V	Q	K	R	Q	D	M	K	L	I	V	T	S	A	T	L	D	A	V	K	F	S	Q	Y	F	Y	E	A	P	I	F	T	I	P	G	R	T	Y	P	V	E	I	L	Y	T	K	E	P	E
Query Conservation
Alig confidence														.																												.																		.	.
Template Conservation														.																												.																		.	.
Template Sequence		S	I	A	A	R	G	Y	I	A	T	R	V	.	E	A	G	E	A	A	A	I	F	M	T	A	T	P	P	G	T	S	D	P	F	P	D	T	N	S	P	.	V	H	D	V	S	S	E	I	P	D	R	A	W	S	S	G	F	.	.
Template Known Secondary structure														.		T	T	S								S	S		T	T				S	S				S	S		.										S	S			S	S			.	.
Template Predicted Secondary structure														.																												.																		.	.
Template SS confidence
		294	.	.	.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.		.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.
		778	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	D	Y	L	D	A	S	L	I	T	V	M	Q	I	H	L	T	E	P	P	G	D	I	L	V	F	L	T	G	Q	E	E	I	D	T	A	C	E	I	L	Y	E	R	M	K	S	L	G	P	D	V	P	E	L	I	I	L	P	V	Y
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	E	W	I	T	D	Y	A	G	K	T	V	W	F	V	A	S	V	K	M	S	N	E	I	A	Q	C	L	Q	R	A	.	.	.	.	.	.	.	.	.	G	K	R	V	I	Q	L	N
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.					S			S							S	S													T	T	.	.	.	.	.	.	.	.	.	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.
Template SS confidence
															350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.										380	.	.	.	.	.	.	.
		838	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.			.	.	890	.	.	.	.	.
Predicted Secondary structure																																																				.	.
Query SS confidence																																																				.	.
Query Sequence		S	A	L	P	S	E	M	Q	T	R	I	F	D	P	A	P	P	G	S	R	K	V	V	I	A	T	N	I	A	E	T	S	L	T	I	D	G	I	Y	Y	V	V	D	P	G	F	V	K	Q	K	.	.	V	Y	N	S	K	T	G	I
Query Conservation																																																				.	.
Alig confidence													.	.	.	.																						.														.	.
Template Conservation													.	.	.	.																						.
Template Sequence		R	K	S	Y	D	T	E	Y	P	K	C	.	.	.	.	K	N	G	D	W	D	F	V	I	T	T	D	I	S	E	M	G	A	N	F	G	.	A	S	R	V	I	D	C	R	K	S	V	K	P	T	I	L	D	E	G	E	G	R	V
Template Known Secondary structure		S	S	S					G	G	G	G	.	.	.	.	G	T				S						G	G	G	G	T	T					.		S																S	T	T
Template Predicted Secondary structure													.	.	.	.																						.
Template SS confidence
		388	.	390	.	.	.	.	.	.	.	.					.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.		420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.
		896	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	Q	L	V	V	T	P	I	S	Q	A	Q	A	K	Q	R	A	G	R	A	G	R	T	G	P	G	K	C	Y	R	L	Y	T	E	R	A	Y	R	D	E	M	L	T	T	N	V	P	E	I	Q	R	T	N	L	A	S	T	V	L	S
Query Conservation
Alig confidence																																			.	.	.	.	.
Template Conservation																																			.	.	.	.	.
Template Sequence		I	L	S	V	P	S	A	I	T	S	A	S	A	A	Q	R	R	G	R	V	G	R	N	P	S	Q	I	G	D	E	Y	H	Y	.	.	.	.	.	G	G	G	T	S	E	D	D	T	M	L	A	H	W	T	E	A	K	I	L	L	D
Template Known Secondary structure						S													T	T	S	S			S	S									.	.	.	.	.		S							T	T	B
Template Predicted Secondary structure																																			.	.	.	.	.
Template SS confidence
		443	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.						.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.
		956	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.						1000	.	.	.	.	.	.	.	.	.	1010
Predicted Secondary structure																																														.	.	.	.	.
Query SS confidence																																														.	.	.	.	.
Query Sequence		L	K	A	M	G	I	N	D	L	L	S	F	D	F	M	D	A	P	P	M	E	T	L	I	T	A	M	E	Q	L	Y	T	L	G	A	L	D	D	E	G	L	L	T	R	.	.	.	.	.	L	G	R	R	M	A	E	F	P	L	E
Query Conservation																																														.	.	.	.	.
Alig confidence																					.	.	.	.	.	.	.	.	.	.	.	.	.													.	.	.	.	.
Template Conservation																					.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	I	H	L	P	N	G	L	V	A	Q	L	Y	G	P	E	R	D	K	.	.	.	.	.	.	.	.	.	.	.	.	.	T	Y	T	M	D	G	E	Y	R	L	R	G	E	E	R	K	T	F	L	E	L	I	K	T	A	D	L	P
Template Known Secondary structure		T	S		B	T	T	T	B						G	G	G	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.					T	T	T	T																T	S
Template Predicted Secondary structure																					.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		498	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.														.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.
		1011	.	.	.	.	.	.	.	.	1020
Predicted Secondary structure
Query SS confidence
Query Sequence		P	M	L	C	K	M	L	I	M	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	W	L	A	Y	K	V	A	S	N
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		545	.	.	.	.	550	.	.	.	.